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HS Code |
514809 |
| Cas Number | 110-64-5 |
| Chemical Formula | C4H10S2 |
| Molecular Weight | 122.25 g/mol |
| Iupac Name | Butane-1,4-dithiol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 192-194 °C |
| Melting Point | -58 °C |
| Density | 1.114 g/mL at 25 °C |
| Flash Point | 90 °C (closed cup) |
| Solubility In Water | Slightly soluble |
| Odor | Strong, unpleasant (thiol-like) |
| Refractive Index | 1.539 at 20 °C |
| Vapor Pressure | 0.4 mmHg at 25 °C |
As an accredited 1,4-Butanedithiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 1,4-Butanedithiol is packaged in a 100 mL amber glass bottle with a secure screw cap and hazard labeling. |
| Shipping | 1,4-Butanedithiol should be shipped in tightly sealed containers, protected from light, heat, and moisture. It must be labeled as a flammable and toxic liquid, compliant with applicable hazardous material transport regulations. Use secondary containment and ensure proper ventilation to prevent the buildup of vapors during transit. Handle with care. |
| Storage | **1,4-Butanedithiol** should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from heat, sparks, and open flames. Keep it separated from strong oxidizers, acids, and bases. Due to its strong odor, containers should be sealed and stored in a fume hood or well-ventilated chemical storage cabinet, with appropriate spill containment measures in place. |
Applications of 1,4-Butanedithiol in Industrial ManufacturingAs a direct producer of 1,4-butanedithiol, we serve specialized industrial customers seeking reliable quality for dedicated applications in polymer synthesis, pharmaceutical intermediates, electronics, and fine chemical manufacturing. Our material meets stringent process and compliance standards tailored for real-world integration across advanced downstream industries. 1. Polymer Crosslinking for High-Performance ElastomersLeading elastomer manufacturers incorporate 1,4-butanedithiol as a bifunctional crosslinker for producing heat- and chemical-resistant rubber materials, targeting applications where superior flexibility and durability are critical. Our clients optimize the balance of crosslinking density and mechanical profile for use in seals, gaskets, and automotive parts that demand elevated stability in aggressive chemical environments. Industry compliance standards
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2. Pharmaceutical Intermediate SynthesisSelected pharmaceutical process houses utilize 1,4-butanedithiol as a sulfur source or key thiol reagent for synthesizing intermediates in the preparation of antibiotics, antithrombotic agents, or custom molecule scaffolds. Its high functional group tolerance and reactivity enable precise transformations required for critical API precursor construction. Industry compliance standards
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3. Electroplating Additive for Copper and Precious Metal DepositionElectronic component manufacturers depend on 1,4-butanedithiol as a grain refiner and leveling agent in acid copper and gold electroplating baths. It modulates deposit morphology, controls grain growth, and improves adhesion in the fabrication of printed circuit boards and microelectronic connectors. Industry compliance standards
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4. Thiol-Functionalized Monomer for Specialty PolymersFunctional polymer producers employ 1,4-butanedithiol as a co-monomer or chain extender in syntheses where pendant thiol groups enhance polymer reactivity, adhesion, or crosslinking potential, especially in coatings designed for metal adhesion or chemically resistant films. Industry compliance standards
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5. Chemical Reducing Agent in Specialty Fine Chemical ProductionProducers of fine chemicals rely on the reducing properties of 1,4-butanedithiol for selective reduction of disulfide bonds in target molecules or as a mild reductant in controlled organic syntheses, supporting production of flavors, fragrances, and specific specialty intermediates. Industry compliance standards
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6. Curing Agent in Modified Epoxy and Resin SystemsManufacturers of advanced composite resins select 1,4-butanedithiol for its difunctional thiol reactivity, enabling controlled curing and modification of epoxy matrices, which is critical in aerospace, electronics encapsulation, and chemically resistant flooring. Industry compliance standards
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1,4-Butanedithiol reflects decades of close attention to both process optimization and user requirements on the factory floor. Few understand the quirks and strengths of this chemical the way our operators and chemists do, having produced it batch after batch. We see every step, from raw materials arriving at daybreak to the final drum’s seal—so we see and solve the real-world issues customers face. Our 1,4-Butanedithiol comes off the line at high purity, thanks to a continuously refined process, and runs clear, with a characteristic odor expected from a genuine dithiol.
Quality here is more than a number on a spec sheet. Our quality department takes samples from every lot, running them through gas chromatography systems tuned for sulfur compounds. This lets us catch trace byproducts and avoid sending out a product with impurities that could sabotage the next steps in your application, especially in sensitive catalyst systems or fine organic syntheses. We don’t keep secrets about how product quality shifts batch to batch, nor do we change our manufacturing practice just for the sake of cost—it’s not uncommon for our technical staff to pick up the phone and explain to a customer what they’ll see if they push the material past the recommended storage temperature.
Many buyers ask about “model,” but we focus more on the manufacturing route and process controls than fancy packaging or part numbers. Our plant sticks with the butadiene and sodium hydrogen sulfide route, monitored closely to minimize odd-chain dithiols and maintain consistent boiling range. This method offers another benefit—not much extraneous thiol content appears, so what you order is what you get: 1,4-Butanedithiol, and little else. Typically, we ship in corrosion-resistant drums; smaller pack sizes are available for R&D. High-purity chromatograms—often 99% or higher, depending on downstream use—stand as our standard.
A curious thing customers notice is the product’s pungent sulfurous odor, even detectable in very small leaks or container openings. We have taken steps to ensure drums are vapor tight and use only gaskets that do not degrade on contact with thiols—an issue that plagued old-style packaging. This practical attention to containment pays dividends later for those working with the material in enclosed synthesis cabinets or pilot plants.
Downstream, 1,4-Butanedithiol finds use in three main areas: as a cross-linker in polymer chemistry, as a building block for organic synthesis, and as a ligand in catalyst systems. We see repeat orders from major elastomer producers who modify rubbers for toughness or flexibility, using our dithiol’s terminal SH groups to form reliable bridges in the polymer backbone. It’s also a common sight in custom synthesis projects—many of them confidential—where its clean dithiol structure saves synthetic routes from extra purification steps.
Manufacturing experience tells us that not all applications need ultra-high purity. For polymer cross-linking, trace levels of higher sulfur analogs rarely interfere with performance, so we often offer a cost-effective technical grade for volume users. In precious metal catalyst laboratories, even a half-percent impurity can throw off activity, so our high-purity offering gets extra scrubbing and fractionation. We make these decisions after real feedback—what worked, what clogged a customer’s reactors, what products needed changing after years of use. Mistakes and fixes on our end help us preempt headaches on yours.
Over time, we’ve seen smaller pharma and specialty chemical labs struggle with the practicalities of handling dithiols. The strong and persistent odor attracts unwanted attention unless strict containment measures are followed. We advise our buyers early about double-sealing protocols and supply matched PTFE-lined caps to mitigate odor release in small container use. Having walked through industrial sites large and small, our technical advisors provide support for everything from fume scrubber troubleshooting to rapid neutralization techniques in spill situations. While safety data is always available, our best insights come from years of fielding emergency calls and seeing firsthand what works under pressure.
A question that comes in every month: why choose 1,4-Butanedithiol over similar compounds like 1,2-ethanedithiol, 1,6-hexanedithiol, or even monothiols like 1-butanethiol? The answer has always been chemical structure dictating function. Our product’s 1,4-linkage—the four-carbon alkyl spacer—hits a sweet spot for cross-linking and molecular assembly tasks. With shorter dithiols like 1,2-ethanedithiol, spatial constraints sometimes prevent the formation of larger, well-ordered networks. Extended dithiols can add unwanted flexibility or reduce cross-link density. The four-carbon backbone of our material often delivers the right blend of flexibility without sacrificing mechanical strength in polymers.
Monothiols, though sharing the familiar scent and some reactivity, simply cannot link polymer chains or coordinate metals in the same fashion. Higher molecular weight dithiols—longer chains—bring handling headaches: higher viscosity, slower mixing, and more expensive purification steps. Through customer collaborations, we’ve collected performance data showing how 1,4-Butanedithiol helps maintain tensile strength and elasticity in specialty elastomers, or how it bonds homogeneously in certain epoxy systems. A few decades ago, early users favored more available short-chain dithiols, but as synthesis routes matured, we found the four-carbon variant outperforms its neighbors on key industry benchmarks.
In catalysis research, we see a similar story. The symmetric BDT molecule fits compactly into complex structures, enabling precise ligand engineering around metal centers. Substituting with uneven chain lengths often disrupts symmetry and binding, so custom catalyst developers stay loyal to 1,4-Butanedithiol—sometimes after expensive trials with alternatives that failed to deliver predicted activity.
In shipping and storage, the lessons that stick don’t come from manuals—they come from field complaints and accident reports. 1,4-Butanedithiol, by nature, reacts slowly with air and light, but over time, oxidation can creep in. We store drums under nitrogen blanketing in cool warehouses, avoiding metal shelves where corrosion could leach into the product. Leakage reports spark changes in container design—double gaskets, leak-tested closures, and site-specific secondary containment advice for high-throughput customers. Having seen a single leaky drum stench up an entire loading dock, we push for secondary seals and run odor checks before every outbound load.
The shelf life in sealed containers regularly goes beyond a year under proper storage, though frequent drum opening shortens active life. Refrigeration, though not officially required, often extends working stability. Some customers ask about freezing or inert gas transfers for high-purity specifications, and from experience, we advise only where critically required—our staff can estimate risk trade-offs and share data from other users facing similar constraints.
Emergency response isn’t left to chance. Facilities using bulk 1,4-Butanedithiol count on our guidance for spill kits, air handling tweaks, and disposal best practices. Smaller users may only need reminders about local ventilation or neutralizer keeping. Either way, our support comes from taking calls at 2am and troubleshooting warehouse incidents with buyers, not just from paperwork.
Recently, new rules from downstream customer countries have pressed our team to revise every MSDS and double-check batch-to-batch residuals. We’ve responded with process improvements, better waste capture, and transparent disclosures on trace contaminants. We track evolving trends: pressure for lower sulfur releases to air, new restrictions on thiol handling, audits focused on chemical traceability, and the rapid advance of environmental accreditation. Smaller customers may not get targeted in regulatory sweeps, but the major manufacturers—those scaling 1,4-Butanedithiol usage—have already told us stricter documentation requirements are now non-negotiable.
Our plant integrates capture and abatement for thiol vapors. Scrubber maintenance cycles grew shorter after a spike in regional inspections, and we share both data and improvement logs with manufacturers who adopt similar compliance measures. This sort of response keeps the product viable for sensitive markets and reduces the need for last-minute reformulations or rushed supplier switches. The regulatory landscape keeps shifting, but our process engineers track each change with the same hands-on approach as our production chemists—one foot in the lab, one on the factory floor.
As sustainability expectations climb, we examine feedstock origins, energy intensity, and believe in honest reporting of our carbon footprint—even when those reports spark tough conversations with customers seeking “greener” alternatives to classic dithiols. Most alternatives fail on cost or function, but together with research collaborators, we keep looking for routes that reduce waste and energy input step by step, instead of promising the world then walking it back.
In real operation, few buyers care just about the price per kilo. Questions center on how readily our 1,4-Butanedithiol fits known processes and whether new users can swap it in without slowdowns or extra clean-ups. Compatibility with established workflows means more than just ticking boxes—customers measure purity by how often their reactors need cleaning or catalyst lifetimes drop. We get honest feedback from veteran plant managers and lab techs frustrated by off-grade shipments or shifting upstream feedstock sources.
Manufacturing, storage, and delivery process improvements are driven not just by quarterly targets, but by the cost of callbacks and production interruptions. The product’s chemistry creates value only if its handling at each site matches customer routines. Knowing the impact of a five-degree swing in loading dock temperature or the knock-on effect if a pump seals fails isn’t something learned from textbooks, but from standing next to a customer during maintenance day.
Nobody producing chemicals at scale gets it right every time. Our worst months result in more field visits and follow-ups, not fewer. Continual tuning of the process based on new demands, unforeseen impurities, and fresh applications underpins every lot shipped. We ask customers for unvarnished reports when things go sideways, logging every incident for tech meetings, and translating recurring issues into actionable process changes. Instead of hiding batch numbers, our team tracks them through to end-use customers, so tracing any problem doesn’t stop short at sales.
Engineers and plant operators reach out with specific questions: How often does high-purity BDT sludge up peristaltic lines? Can sodium byproducts from less-refined BDT batches be reclaimed safely? We field those calls because we stand behind every drum and share honestly what our production reality looks like.
Doubt in a product’s suitability often arises from lack of visibility into manufacturing realities. Our buyers—many with years of hands-on synthesis experience—insist on seeing not only reams of analytical data but evidence of consistent, repeatable quality. Our production team delivers daily proof through stringent process logging, hands-on sampling, and direct troubleshooting. Purchasing from the manufacturer closes that critical loop—you see the continuous improvement as regulations tighten, applications broaden, and global supply chains twist in unexpected ways.
We recognize the need for absolute reliability in bulk chemical shipments and nimble response for R&D scale-ups. If a new catalytic application calls for a tighter impurity profile or shipping logistics impose time limits on cold-chain storage, our manufacturing team brings up the practical considerations: changes in logistics, the cost of additional packaging, or reformulating based on the latest feedback from major users.
Our work with 1,4-Butanedithiol reveals much about the broader business of chemical manufacturing. Each drum represents the sum of raw material supply, operator diligence, and honest communication with the end user. Chemical structure gives the material its broader usefulness, but day-to-day handling makes its reputation. We recognize this not in abstract accolades or generic praise, but in long-term partnerships with users who depend on the product to keep their lines running and their innovations moving.
For anyone questioning the finer points of 1,4-Butanedithiol specification or best use, our door is always open. As those who see every detail, from base feedstock to broken gaskets, we know each improvement we make upstream simplifies the work of users downstream. In the culture of direct manufacturing, real expertise doesn’t come from outside consultants or market trends, but from the lived experience of producing chemicals day after day, learning from problems, and staying accountable.
Real trust in a product like this grows from how consistently it performs with the demands of production realities. Our 1,4-Butanedithiol stands as the result of accumulated adjustments—by a team who knows what’s at stake when a customer opens the drum, sets up the reactor, and puts another batch into production.