Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

1-(4-Bromophenyl)Octane

    • Product Name 1-(4-Bromophenyl)Octane
    • Alias 4-Bromo-1-phenyloctane
    • Einecs 68411-48-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    901022

    Cas Number 61347-62-4
    Chemical Name 1-(4-Bromophenyl)octane
    Molecular Formula C14H21Br
    Molecular Weight 269.22 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 338.1°C at 760 mmHg
    Density 1.13 g/cm³ at 25°C
    Refractive Index 1.511
    Purity Typically >98%
    Smiles CCCCCCCC1=CC=C(C=C1)Br
    Synonyms 4-Bromophenyloctane
    Solubility Insoluble in water, soluble in organic solvents
    Flash Point 163°C
    Storage Conditions Store at room temperature, keep container tightly closed

    As an accredited 1-(4-Bromophenyl)Octane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 1-(4-Bromophenyl)octane is supplied in a tightly sealed amber glass bottle with a tamper-evident cap for safety.
    Shipping 1-(4-Bromophenyl)Octane is shipped in sealed, secure containers to prevent leaks or contamination. It is packed according to chemical transport regulations, with clear labeling and safety documentation. The packaging ensures stability during transit and protects against moisture, heat, and mechanical damage. Handle carefully and store in a cool, dry place.
    Storage Store 1-(4-Bromophenyl)octane in a tightly sealed container, away from direct sunlight, heat sources, and incompatible materials such as strong oxidizers. Keep it in a cool, dry, well-ventilated area. Ensure the storage area is equipped with spill containment measures. Clearly label containers and restrict access to authorized personnel. Handle with appropriate personal protective equipment to prevent exposure.
    Application of 1-(4-Bromophenyl)Octane

    Applications of 1-(4-Bromophenyl)Octane in Industrial Manufacturing

    1-(4-Bromophenyl)Octane serves as a specialized halogenated intermediate in several advanced chemical manufacturing contexts. Our proprietary synthesis and purification expertise ensures consistent quality for demanding formulation and integration processes across multiple downstream sectors.

    1. Pharmaceutical Intermediate Synthesis

    Pharmaceutical manufacturers use 1-(4-Bromophenyl)Octane as a key building block for the assembly of complex molecular structures in the synthesis of certain targeted APIs, especially brominated, alkylated aromatic compounds. Its linear octyl chain and brominated phenyl group allow for selective further substitution, crucial during late-stage functionalization steps. Typical usage occurs during Grignard or palladium-catalyzed cross-coupling reactions, where precise stoichiometry and impurity control influence both yield and qualification for further clinical development or commercial formulation.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 211 (Manufacturing, Processing, Packaging, or Holding of Drugs)
    • European Pharmacopeia standards for synthetic intermediates
    • ISO 9001:2015 Quality Management for chemical production

    Typical usage ratio

    • 5–20% molar equivalent in cross-coupling or alkylation stages, adjusted based on desired API yield and side product suppression

    Downstream process integration

    • Direct addition in late-stage intermediate coupling as a reactive substrate
    • Batchwise input into automated reactor systems for scale-up API manufacture
    • Input for bromine-atom transfer polymerization catalyst pre-mixing
    • Isolation via solvent extraction and purification for onward reaction

    Final product types

    • Brominated pharmaceutical intermediates
    • Final active pharmaceutical ingredients for oncology or CNS applications
    • Regulated research and development samples
    • Registered custom API intermediates for CRO/CDMO clients

    2. Specialty Agrochemical Synthesis

    Researchers and formulators in the crop protection sector utilize 1-(4-Bromophenyl)Octane during the synthesis of certain halogenated pesticide and fungicide bases. Its aromatic-bromo moiety provides a platform for electrophilic aromatic substitution, particularly when preparing long-chain hydrophobic derivatives intended for controlled soil or foliar application. Inclusion is typically in the core step where selective alkylation impacts bioactivity spectrum and field persistence.

    Industry compliance standards

    • FAO/WHO Technical Grade Pesticide Specifications
    • EPA 40 CFR Part 158 (Data Requirements for Pesticides)
    • OECD Principles of Good Laboratory Practice (GLP)
    • ISO 17025:2017 Laboratory standards for pesticide analysis

    Typical usage ratio

    • 8–15% w/w as a precursor in batch synthesis, with adjustments according to the required halogen content of the target molecule

    Downstream process integration

    • Entry into closed reactor vessels for aromatic substitution with nitrogen or sulfur-containing secondary reactants
    • Integration after catalyst charging for selective halogen preservation
    • Post-reaction distillation and phase separation before formulation blending
    • Output to crystallization or purification prior to technical concentrate manufacture

    Final product types

    • Brominated fungicide intermediates (e.g., for cereals and viticulture)
    • Precursor chemicals for selective herbicide products
    • Custom agrochemical actives for regional registration
    • Tool compounds in pest resistance management research

    3. Electronic Materials Intermediate

    Manufacturers of specialty monomers and advanced electronic materials integrate 1-(4-Bromophenyl)Octane during the production of organic semiconductors and functionalized aryl compounds. Its alkyl-bromide functionality supports Suzuki-Miyaura and Stille-type cross-coupling, essential for constructing π-conjugated architectures in thin-film transistors and light-emitting devices. Real-world process design involves high-purity handling and controlled input to maintain the electronic grade of the final product.

    Industry compliance standards

    • IPC-4101: Specifications for Base Materials for Printed Boards
    • RoHS Directive 2011/65/EU restriction checks for residuals
    • ISO 14001:2015 Environmental Management for materials supply
    • Internal QC protocols for low ionic/halide contamination

    Typical usage ratio

    • 1–5% w/w as functional monomer feedstock, adjusted for polymer chain length and film morphology

    Downstream process integration

    • Mixed with aryl boronic acids or stannanes under controlled anhydrous conditions
    • Continuous-fed into CVD (Chemical Vapor Deposition) reactors for thin-film polymer assembly
    • Batchwise addition to specialty organic electronic ink formulations
    • Final purification via vacuum sublimation to meet display/semiconductor purity

    Final product types

    • Organic light-emitting diode (OLED) intermediates
    • Semiconductive polymers for flexible electronics
    • Photoresist ingredients
    • Custom organic dielectrics

    4. Fine Fragrance and Flavor Intermediate

    Certain fine chemical houses employ 1-(4-Bromophenyl)Octane in the development of advanced aromatic ingredients intended for luxury fragrance bases and specialized flavor modifiers. The long-chain alkyl benzene motif mimics high-value musks and ambergris analogs, with the bromine atom facilitating downstream functionalization or masking. Formulators utilize it predominantly during the core one or two synthetic steps preceding macrocyclic ketone or ester finalization, under tightly controlled purity standards for olfactive end-use.

    Industry compliance standards

    • IFRA (International Fragrance Association) Code of Practice
    • US FDA 21 CFR Part 172 (Direct Food Additives Permitted for Human Consumption) for flavor chemicals
    • FEMA GRAS (Flavor and Extract Manufacturers Association)
    • ISO 9235 for definition of natural and chemically modified raw materials

    Typical usage ratio

    • 0.5–2% w/w as an intermediate in batch or semi-batch synthesis, adjusted for strength and desired volatility

    Downstream process integration

    • Introduction after initial aromatic acylation or alkylation
    • Processing through reductive debromination or oxidation prior to bulk olfactive blending
    • Pre-concentration by vacuum purification before re-entry into macrocyclic ring closure steps
    • QC sampling for trace residuals prior to IFRA/FEMA certification

    Final product types

    • High-value musk and woody note fragrance ingredients
    • Specialty flavor enhancers and masking agents for beverages
    • Custom aroma chemicals for perfumery houses
    • Olfactive reference molecules for sensory evaluation

    5. Advanced Polymer Additives

    Additives manufacturers in the high-performance plastics industry incorporate 1-(4-Bromophenyl)Octane during the formulation of tailored polymer modifiers where brominated hydrophobes yield niche fire retardancy or surface property adjustments. The aromatic and alkyl components synergize in impact modifier blends or niche copolymer segments, especially in co-extrusion or masterbatch production for applications where low halogen release is a requirement.

    Industry compliance standards

    • UL 94 Flammability Standards for plastics
    • REACH Regulation (EC) No 1907/2006 for registration and source traceability
    • ISO 11357 for polymer thermal analysis
    • ASTM D2863 Oxygen Index Testing for fire-retardant polymers

    Typical usage ratio

    • 2–7% w/w in compound formulas, with adjustment based on desired LOI (Limiting Oxygen Index) and physical properties of the finished part

    Downstream process integration

    • Dry blending during masterbatch production before melt compounding
    • Addition inline with reactive extrusion equipment for engineered plastics
    • Dispersed in monomer or oligomer feed for in-situ copolymerization
    • End-use testing in injection-molded or extruded goods

    Final product types

    • Fire-retardant polyolefins or styrenics
    • Specialty elastomers with hydrophobic and aromatic modifications
    • Polymer masterbatches for automotive interior parts
    • Electronics housing grades with targeted thermal resistance
    Free Quote

    Competitive 1-(4-Bromophenyl)Octane prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing 1-(4-Bromophenyl)Octane: Reliable Building Block from an Experienced Manufacturer

    Our Experience with 1-(4-Bromophenyl)Octane

    Over years on the production floor, we’ve worked hands-on transforming raw materials into specialty intermediates that help customers branch into new synthesis pathways. Among these materials, 1-(4-Bromophenyl)Octane stands out for its versatility and performance. Chemists who seek to build more complex molecules often rely on robust aryl alkane frameworks, especially brominated chains like ours. Our team handles every batch ourselves—from the purification columns to the reactor temperature checks. The hands-on knowledge we gain each day guides process refinements and helps us troubleshoot for customers who push the boundaries with their research.

    Core Features Shaped by Customer Feedback

    The molecule’s backbone, with a bromine atom attached to the para position of a phenyl ring and an octyl chain extending from it, gives it substantial value in both research and advanced manufacturing. We kept purity above 98% consistent, because every lab and plant that works with substituted aromatic alkyls expects reproducibility. Over years, customers pushed us to develop clean, stable batches without persistent by-product tails that could disrupt synthesis downstream. We took their feedback, upgraded our filtering process, and invested in better analytical tracking, ensuring that each drum shipped reflects expectations at scale—not just on a spec sheet.

    What Sets Our 1-(4-Bromophenyl)Octane Apart

    Consistency matters the most. Color, flow, and shelf life come up in every discussion with R&D chemists. We listen closely when they report on reaction outcomes, and we use these stories to optimize each production run. Unlike generic grades sometimes found in the market, our product matches the requirements for sensitive coupling reactions and long synthesis sequences. A fresher product means a higher yield, fewer purifications, and better reproducibility from bench to pilot plant. Batch records and continuous NMR, HPLC, and GC evaluations back every claim we make. If a solvent system change advances product performance, our team adjusts protocols long before customers notice.

    Practical Applications and Their Challenges

    This molecule gets used as a key intermediate to introduce the aryl and bromine moieties into longer carbon frameworks. Organic chemists and pharmaceutical developers use it to build custom functional groups, often aiming to create new candidates or fine-tune bulk material properties. In actual production runs, coupling and substitution reactions involving this compound require steady hands at every stage—from controlling temperatures during alkylation to watching for trace impurities that can ruin whole batches. We face similar challenges, so we understand how small problems in a feedstock can balloon in subsequent steps.

    Customers in agrochemicals, pharma intermediates, and materials science reach for this compound for one reason: the bromine accelerates further modifications under straightforward reaction conditions. Based on weekly calls with process chemists, we noticed that chain extension reactions and site-specific substitutions depend heavily on the absence of moisture and reliable bromine introduction. Our systems focus on limiting water load and minimizing by-product formation. Even after years of operation, we keep dye tracing and moisture analysis in the routine, ensuring the chemistry flows as intended.

    How Our Production Philosophy Benefits Users

    Our production process starts with careful raw material selection. As the team works with both small and bulk orders, we keep close tabs on the physical consistency of every shipment. A batch of 1-(4-Bromophenyl)Octane should arrive as a near colorless liquid, stable at room temperature, and without odorous artifacts. Years of dialogue with buyers taught us that trace impurities—sometimes invisible without very sensitive equipment—affect downstream processes. So, before a batch leaves our hands, it faces a round of GC and NMR checks, and these controls reduce the risk of surprises once the chemical reaches a reactor.

    Every time we update synthetic methodology, senior chemists in our group review process safety, substance stability under various logistics conditions, and impact on overall throughput. The industry faces tighter controls on batch reproducibility, and we share these concerns. By tracking each process parameter and maintaining full traceability, we bridge trust between our facility and each project that uses our product. Our formulation approach aims at stability for extended storage, even when faced with variable global shipping temperatures.

    Supporting Diverse Synthesis Routes

    Manufacturers and researchers use 1-(4-Bromophenyl)Octane in numerous functionalization and cross-coupling applications. The compound’s strong carbon-bromine bond and long alkyl tail open the door to preparations of arylalkanes and further halogenations. Our years of customer support revealed an ongoing demand for high selectivity and minimal isomerization. When the team troubleshoots with a partner lab, most of the conversation centers on reactivity control and minimizing decomposition under catalytic conditions. Every improvement we roll out in our plant reflects these field experiences.

    Pharmaceutical companies searching for synthesis routes to new scaffolds often cite the need for clean mono-substituted aryl bromides. By maintaining a steady supply and ensuring lot-to-lot reliability, our operations help streamline their research and process scale-up. Similarly, developers in advanced materials use this compound for rigidifying alkyl-aryl polymers. These cycles run for months, so process interruptions can cause significant costs. Tight feedback loops between chemists in our production line and external project teams help everyone hit deadlines without sacrificing chemical integrity.

    Troubleshooting: Addressing Real-World Manufacturing Issues

    Typical issues that come up during use involve moisture contamination, by-product retention, or solvent mismatch. On several occasions, we’ve fielded late-night calls from process engineers whose reactions paused due to either gas evolution from residual solvent or odd color changes. Years ago, a mishap with incomplete drying forced us to overhaul our final filtration and vacuum handling. Now, drying cycles synchronize with downstream process needs, and sample lots see stricter release standards. Our plant team recognizes the stakes—a problematic intermediate sets back days or weeks of effort, not to mention the material costs.

    Customers sometimes require product in volumes higher than usual. Scaling up requires extra diligence because impurities that are negligible at gram or kilogram scale might cause significant issues at several tons. Through trial, error, and steady communication with user sites, we’ve refined a system that controls run-to-run variation and ensures consistent product flow. If a refinement in purification or new impurity triggers concern for a major user, our response is swift, and we share full analytical results so all parties understand the problem and solution. Our ongoing goal: anticipate problems before they reach the customer’s plant.

    Spotting the Differences from Similar Products

    Compared to other aryl bromides and long-chain phenylalkanes, 1-(4-Bromophenyl)Octane combines a balance of reactivity and manageable physical properties. Shorter-chain analogs have higher volatility and sometimes complicate handling in large-scale synthesis. In longer, more substituted compounds, solubility and processability pose challenges for both bench chemistry and manufacturing. Our product gives a comfortable boiling range for typical solvent systems and resists decomposition better under common reaction conditions found in laboratory and pilot-scale setups.

    Structurally, bromine in the para position ensures more predictable orientation for cross-coupling reactions. End-users have shared, in feedback sessions, that ortho- and meta-substituted analogs introduce steric hindrance, reducing yield especially in Suzuki or Grignard reactions. The alkyl tail in 1-(4-Bromophenyl)Octane adds hydrophobicity for targeted material applications, particularly in surface coatings and advanced polymers, where other similar molecules fall short. Our focus on pure para-isomer means projects that demand accurate regioselectivity can proceed without worrying about unexpected by-products or isomeric drift.

    Common Misconceptions and Lessons from the Field

    The notion that all aryl bromides perform interchangeably doesn’t hold in practice. Even small variances in purity or branching affect both the kinetics and outcome of multistep synthesis. In our early years, some batches with trace halide by-products led to customer complaints, which we now guard against with extra purification passes. Documentation of these cases guides our training for new workers, ensuring each generation understands real-world consequences of slack process controls.

    We’ve seen examples where labs switch between suppliers on price alone, only to run into downstream quality issues—often more expensive than the immediate savings. Data from collaborative projects demonstrated that mismatched product quality leads to additional recrystallizations, more solvent waste, and failed experiments. Our philosophy remains: predictable behavior in every reaction matters more than cutting a corner for short-term gain.

    Upholding E-E-A-T in Our Everyday Practice

    Extensive experience and daily oversight drive our confidence in this compound’s performance. Every production run involves close monitoring of yield, impurity profile, and storage stability. Data generated by our own teams, in combination with feedback from industrial and academic users, informs every improvement. Our technical staff logs all process adjustments and shares best practice advice with customers regularly. Such transparency supports decisions that impact both safety and efficiency in downstream work.

    We rely on robust evidence, derived from both in-house and third-party analysis, to back up every claim about product quality and suitability. No shortcuts are taken with documentation, and all technical bulletins reflect real production experience, not sales commitments or theories. Our senior chemists, with years at the reactor line, personally handle complex queries and breakdowns, ensuring users have access to trustworthy guidance rather than automated responses or generic call sheets.

    Building Solutions, Not Just Supplying a Product

    Challenges in chemical manufacturing come from every direction: raw material fluctuation, transport delays, unique application scenarios, and regulatory changes. Our role goes beyond mixing, distilling, and packaging. We work to anticipate user needs through constant improvement, tracking real performance data in partner labs and internal R&D. We keep direct lines open for technical discussion, because half the value lies in sharing lessons learned from our own successes and setbacks, not just sending out COAs.

    Quality cannot rely on final inspection alone. We trace sources, understand reaction bottlenecks, and talk frankly about risks, especially when clients propose new applications. Every process change—whether to enhance purification or bolster safety—runs through full validation with pilot trials, and every member of the production team engages in the review. We share sample data sets, highlight production quirks, and remain accessible for site-specific troubleshooting, striving to make every project that uses 1-(4-Bromophenyl)Octane more predictable from start to finish.

    The Path Ahead: Addressing Changing Industry Needs

    Evolving regulatory standards and rising product scrutiny force us to stay agile. Feedback cycles run tight and continuous improvement remains a priority. By working closely with buyers and end users, we adjust protocols quickly to meet emerging expectations on everything from purity to packaging sustainability. As new synthetic pathways are published and customer applications shift, we match our expertise to the requirement—whether it is tighter impurity specs or different delivery formats. Our on-the-ground knowledge, built through years of refinement, separates us from copycat suppliers who lack direct manufacturing insight.

    Risk management stands front and center in decisions around each production run. Unexpected moisture incursion, temporary process upsets, or odd-ball test results all see immediate review. Each time a team flags a challenge, senior staff revisits variables, sometimes pausing work to check new analytical results or compare with customer feedback. This loop builds a culture of learning and commitment, connecting every member of our workforce with user satisfaction and product reliability.

    Summary and Ongoing Commitment

    Supplying high-quality 1-(4-Bromophenyl)Octane is not just a process—it is a commitment to our partners’ trust. By building expertise over hands-on manufacturing and long-term collaboration, we deliver more than a chemical. Each year, updated production controls, data feedback, and open communication with users help us refine quality, predictability, and applicability. Our customers push us to new heights, and in facing their real-world challenges, we grow our own experience—and pass those lessons on in the form of better products and reliable support. We look forward to supporting even the most demanding projects that rely on a foundation of technical integrity, transparency, and continuous learning.