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1,4,5,8-Tetrahydroxyanthraquinone

    • Product Name 1,4,5,8-Tetrahydroxyanthraquinone
    • Alias quinizarin
    • Einecs 208-559-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    642145

    Cas Number 81-64-1
    Molecular Formula C14H8O6
    Molecular Weight 272.21 g/mol
    Iupac Name 1,4,5,8-Tetrahydroxyanthracene-9,10-dione
    Appearance Yellow to orange powder
    Melting Point 310-312 °C (decomposes)
    Solubility In Water Slightly soluble
    Density 1.8 g/cm³ (estimated)
    Pubchem Cid 11293
    Synonyms Quinalizarin, Solvent Blue 10
    Pka 6.4 (for one of the phenolic groups)
    Smiles C1=CC2=C(C(=C1O)O)C(=O)C3=C(C2=O)C=CC(=C3)O
    Inchi InChI=1S/C14H8O6/c15-7-1-3-9-11(5-7)13(17)8-2-4-10(6-12(8)16)14(9)18/h1-6,15-18H
    Color Index Number 58000

    As an accredited 1,4,5,8-Tetrahydroxyanthraquinone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging consists of a 25g amber glass bottle with a secure screw cap, labeled "1,4,5,8-Tetrahydroxyanthraquinone, analytical grade."
    Shipping 1,4,5,8-Tetrahydroxyanthraquinone is shipped in tightly sealed containers to prevent moisture and contamination. The packaging complies with chemical safety regulations, including proper labeling and hazard identification. Transport is typically via ground or air, depending on the destination, and must adhere to relevant local, national, and international shipping guidelines for laboratory chemicals.
    Storage 1,4,5,8-Tetrahydroxyanthraquinone should be stored in a tightly sealed container, in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers. Protect from light and moisture. Store at room temperature and avoid excessive heat. Proper labeling and handling precautions should be followed to prevent accidental contact, ingestion, or inhalation. Use secondary containment if necessary.
    Application of 1,4,5,8-Tetrahydroxyanthraquinone

    Applications of 1,4,5,8-Tetrahydroxyanthraquinone in Industrial Manufacturing

    As a direct chemical raw material producer, we supply 1,4,5,8-tetrahydroxyanthraquinone for critical uses across multiple downstream manufacturing sectors. Below, we detail its specific industrial applications and integration profiles based on actual end-user demand and regulatory compliance requirements.

    1. Vat Dyes for Textile Industry

    Textile dye manufacturers incorporate this material as a primary intermediate in the synthesis of vat dyes, especially for cellulosic fibers. This compound enables the creation of vibrant, wash-fast colors required by leading apparel and home textile brands. Our product meets rigorous purity benchmarks to support dye makers’ strict quality control and coloration consistency from batch to batch.

    Industry compliance standards

    • OEKO-TEX Standard 100
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals Manufacturing Restricted Substances List)
    • REACH Regulation (EC) 1907/2006
    • ISO 9001:2015 Quality Management System

    Typical usage ratio

    • 5–12% by weight in dye formulation, adjusted for shade depth and fiber type
    • Careful monitoring required to balance hue intensity against fiber reactivity

    Downstream process integration

    • Used in the oxidative condensation phase of vat dye synthesis
    • Introduced prior to leuco compound formation and dye paste preparation
    • Critical to both batch and continuous dye manufacturing lines

    Final product types

    • Denim indigo vat dyes
    • Brilliant orange and red textile dyes for cotton
    • High-fastness black dyes for industrial fabrics
    • Heat-transfer printing inks for textiles

    2. Synthesis of Quinizarin Pigments for Coatings

    Industrial pigment producers use this raw material to synthesize quinizarin derivatives, which go into high-performance organic pigments needed for coatings and plastics. The resulting colorants deliver strong light stability and heat resistance, meeting automotive, industrial, and packaging standards. Our stringent processing controls help pigment makers ensure batch reproducibility and regulatory traceability.

    Industry compliance standards

    • EN 71-3 Safety of Toys – Migration of Certain Elements (for pigments in toy coatings)
    • ASTM D4236 (Labeling of Art Materials)
    • ISO 1248 (Pigments -- Specifications and methods of test)
    • RoHS Directive (2011/65/EU, as relevant for electronics coatings)

    Typical usage ratio

    • 6–18% by weight as precursor in pigment couplings
    • Dosage optimized per product line target shade and opacity

    Downstream process integration

    • Enters the diazotization and coupling stage for pigment synthesis
    • Filtered and milled to required particle size distribution for coating dispersibility
    • Direct introduction to aqueous and solvent-based pigment processing lines

    Final product types

    • Quinizarin violet and magenta pigments for metal coatings
    • Organic pigment concentrates for PVC and polyolefin plastics
    • Automotive refinish paints (heat-resistant)
    • High-grade printing ink colorants

    3. Electrochemical Battery Materials

    Battery manufacturers increasingly utilize this compound as an organic cathode material or redox-active additive in rechargeable battery systems, particularly for emerging aqueous and non-aqueous flow batteries. The molecular structure contributes to enhanced cycling stability and output capacity in specialty energy storage products. Our advanced purity controls address critical supply chain needs for electronics and grid-scale battery projects.

    Industry compliance standards

    • IEC 62660-2:2018 (Secondary lithium-ion cells for the propulsion of electric road vehicles — Safety requirements)
    • UN Manual of Tests and Criteria – Battery Transportation (UN 38.3)
    • ISO 9001:2015 and ISO 14001:2015 (Quality and Environmental Management)

    Typical usage ratio

    • 3–8% by mass in organic cathode blend formulations for flow batteries
    • Tested and customized depending on battery cell configuration and capacity demands

    Downstream process integration

    • Dissolved and blended as electrode active component in cathode slurry preparation
    • Pre-treated to remove any residual metallic and anionic impurities
    • Integrated into both pilot and commercial-scale battery cell assembly processes

    Final product types

    • Aqueous organic redox flow batteries for grid storage
    • Specialty batteries for renewable energy installations
    • Prototype lithium/organic hybrid battery cells
    • Low-voltage backup power modules

    4. Photographic and Imaging Chemicals

    Producers of traditional photographic materials and imaging chemicals apply this raw material in fine-tuned oxidation-reduction formulations, such as color developer solutions and photographic dye couplers. Its clean structure and specific reactivity support precision color formation in film and paper processing, meeting archival and production standards in the imaging industry.

    Industry compliance standards

    • ISO 18902:2013 (Imaging materials — Processed imaging materials — Photographic film and prints)
    • ANSI/NAPM IT9.15 (Photographic Activity Test)
    • National Environmental Health and Safety codes for chemical processing labs

    Typical usage ratio

    • 1–5% by weight in developer solutions, carefully titrated for desired color balance
    • Adjusted per processing line speed and desired image density

    Downstream process integration

    • Added to developer concentrate batches prior to dilution
    • Filtered for high-purity requirements in archival imaging workflows
    • Integrated on fully automated film and print processing lines

    Final product types

    • Color negative and reversal photographic films
    • High-resolution color inkjet imaging papers
    • Archival-quality silver halide paper
    • Specialty art reproduction materials

    5. Analytical Chemistry Reagents

    Producers of laboratory-grade diagnostic and analytical reagents use this molecule in chromogenic and redox reactions. It enables sensitive colorimetric detection and trace analysis in environmental monitoring and clinical diagnostics. Our manufacturing ensures batch consistency, supported by documentation for quality system traceability.

    Industry compliance standards

    • ISO 17034:2016 (General requirements for the competence of reference material producers)
    • United States Pharmacopeia (USP) for Analytical Reagents
    • CLSI EP25-A (Evaluation of stability of in vitro diagnostic reagents)

    Typical usage ratio

    • Typically 0.1–2% in reagent formulation, precisely defined by detection protocol
    • Dependent on target analyte sensitivity and matrix compatibility

    Downstream process integration

    • Formulated into chromogenic reagent kits or test blends
    • Quality controlled under GMP or ISO standards for lab use
    • Distributed as bulk component to custom reference material producers

    Final product types

    • Environmental trace metal detection kits
    • Clinical biochemistry test reagents
    • Preparative chemistry colored standards
    • Industrial process monitoring test kits
    Free Quote

    Competitive 1,4,5,8-Tetrahydroxyanthraquinone prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    1,4,5,8-Tetrahydroxyanthraquinone: Meeting Industry Needs with Reliable Quality

    Understanding 1,4,5,8-Tetrahydroxyanthraquinone from the Manufacturer’s Perspective

    Working on the factory floor gives a special view into the production and use of 1,4,5,8-Tetrahydroxyanthraquinone. Often called quinizarin tetrahydroxy or quinizarin tetrahydroquinone in the laboratory, this compound has earned trust in several industries because of its balanced properties and consistent performance. We have spent years refining the synthesis process, tightening quality controls, and listening to downstream users to ensure reliable output batch after batch.

    Our team has witnessed how even small changes in pH, temperature, or crystallization process can affect the properties of 1,4,5,8-Tetrahydroxyanthraquinone. We understand how rough spots in crystal size, residual trace metals, or too much organic solvent can deeply impact its suitability for large-scale applications. Bringing this compound to market takes more than chemistry know-how; it takes attention to detail, a willingness to verify each raw material, and keeping records to trace every step through production.

    Features and Specifications Backed by Experience

    Production runs often highlight just how crucial purity levels matter to the types of industries we serve. Our typical material falls in the 98% purity range, as measured by high-performance liquid chromatography. While some research labs can test new routes with lower-grade inputs, coatings and dyes require every gram to stay inside defined specifications—for color stability, solubility, and chemical reactivity. We run tests for moisture content, heavy metals, and specific contaminants like benzoquinone derivatives, since these can affect reaction outcomes or color brightness. Customers working with high-performance pigments frequently request certificates showing trace analysis and lot-to-lot reproducibility. Meeting these expectations requires continuous monitoring, not just batch-to-batch spot checks.

    Granular or microcrystalline versions appeal to large-scale users needing a dust-free material that moves smoothly through production lines. Finer fractions, on the other hand, benefit chemists needing rapid and homogeneous dissolution for organic syntheses. By adapting our drying and grinding steps, we support both industrial and academic customers seeking 1,4,5,8-Tetrahydroxyanthraquinone in compatible forms.

    We handle material in lined drums or large poly bags protected against humidity. This type of packing protects the color, reduces degradation from light or air, and prevents caking, especially in environments that shift from hot to cold within days. Changing seasons taught us never to underestimate environmental effects on a seemingly stable powder. Feedback from customers running 24/7 lines in warm climates led us to develop a more robust packing protocol to maintain integrity.

    Applications: From Pigment Production to Research and Fine Chemicals

    Over the years, our chemical has become essential to manufacturers of anthraquinone-based pigments and dyes, particularly those seeking strong shades and good light fastness. 1,4,5,8-Tetrahydroxyanthraquinone demonstrates strong tinctorial strength, lending deep coloration to plastics, printing inks, textiles, and coatings. The compound’s four hydroxyl groups promote exceptional hydrogen bonding, which boosts adhesion in polymer matrices. This translates into products retaining rich hues even after repeated outdoor exposure or processing at elevated temperatures.

    Paper producers and specialty textile finishers look to this material for vibrant color development and resistance to chemical washing. In organic synthesis, research teams use 1,4,5,8-Tetrahydroxyanthraquinone as an intermediate for developing advanced dyes, sensors, and redox-active compounds. Its well-characterized reactivity profile and predictable redox potential make it a go-to building block when designing new electrochemical materials.

    Battery developers, working on organic or hybrid technologies, show rising interest in using 1,4,5,8-Tetrahydroxyanthraquinone as both redox-active material and a chemical stabilizer. The molecular backbone favors fast and reversible electron exchange, leading to promising studies on organic flow batteries and advanced storage devices. Although these applications are new compared to traditional textile and ink uses, we see more requests each year for high-purity and consistency dedicated to energy applications.

    Some customers in the field of analytical chemistry rely on this product for trace analysis work and standard solutions. In pharmaceutical labs, it serves as a raw material for targeted syntheses of complex molecular structures or as a chromophore in developing new diagnostic reagents.

    What Sets Our Product Apart

    Manufacturing this compound involves far more than following a published protocol. We have improved crystallization and washing procedures compared to earlier approaches, which often left traces of solvents or process impurities. The extra steps pay off in higher purity and longer shelf stability. We invested in secondary filtration and extra drying capacity after a customer’s failure analysis traced impurities back to batch-scale limitations seen at smaller producers. Our scaled procedures help us offer the same specification month after month.

    Some manufacturers substitute lower-purity feedstocks or skip prolonged crystallization, leading to an increase in insoluble particles and color variability. We source only high-grade precursors, using closely monitored reaction times to maximize yield without sacrificing purity. Over the years, we reduced waste and improved the recovery rate by optimizing temperature and agitation controls during oxidation. Advancements in this part of the process helped us offer a tighter purity range than many competitors.

    Customers often ask about the difference between our 1,4,5,8-Tetrahydroxyanthraquinone and other anthraquinone derivatives. Each compound within the anthraquinone family offers unique behavior depending on the number and position of hydroxyl groups. For example, 1,8-dihydroxyanthraquinone delivers different solubility and color strength—useful for some dyes but less for pigment or energy storage work. Our product distinguishes itself with high reactivity and robustness in diverse reactions, making it better suited for demanding formulations.

    Some pigment and dye makers once tried substituting cheaper or more readily available anthraquinones, but they regularly came back to our tetrahydroxy variant for the deep orange-red hues and improved process reliability. End products using 1,4,5,8-Tetrahydroxyanthraquinone show stronger resilience to sunlight and washing—an outcome repeatedly validated in comparison trials.

    Quality Control, Documentation, and Traceability

    Years spent resolving customer issues taught us the value of thorough documentation and transparency. Every production lot receives a unique identification code, tied to input raw materials, reaction conditions, and all test results. This approach supports clients working under demanding regulatory regimes, especially where audits or certifications mean business continuity. We retain representative samples for every batch, allowing rapid troubleshooting if a performance question arises months later.

    Some regulatory frameworks call for detailed documentation down to nanogram levels for impurities. We work closely with third-party labs and update our data reporting as customer requirements evolve. Antique processes using glass-lined reactors and rough filtration often produced product with more variable impurity profiles. Our investments in steel reactors, inert gas blanketing, and inline quality analytics now allow tighter control over every critical parameter. A side benefit is improved environmental safety, as emissions and waste streams sit within internal control limits well below national requirements.

    With the growth of sustainable manufacturing, we also provide environmental data and safety profiles traceable to specific product lots. Our team recognizes that responsible chemical manufacturing stretches beyond the fence line. Auditing waste streams, solvent recovery, and emissions is integral to our daily operations, not just an annual exercise. We work with downstream users to ensure product information stays current, clear, and backed by data, so their finished goods meet market and compliance demands.

    Safety and Handling from Years of Practice

    Workers and customers alike deserve safe, stable product. We know this chemical’s dust can cause respiratory irritation, so we designed bagging and containment systems to keep exposure to a minimum. Our operational staff follows protocols based on risk assessments and incident histories, using dust masks, gloves, and enclosed weighing areas. By learning from minor spills or container damage, we introduced tougher bags and drums, plus periodic training refreshers for warehouse staff.

    Where customers store large quantities, we recommend cool, dry, and well-ventilated conditions, based on how the product reacts to seasonal humidity swings in our own facility. During unusually wet seasons, we saw increased incidents of product clumping in older bags, prompting a transition to newer moisture barrier liners. These changes, based on real storage challenges—not just theoretical models—help the material retain its original appearance and flow properties.

    Industry Trends and Customer Expectations

    Decades in this business have shown us that customer needs continuously evolve. A decade ago, pigment makers cared mainly about color strength and cost. Today, requirements now include environmental data, consistent lot documentation, and performance in specific end-use formulations. Energy storage teams focus on redox neutrality and batch reproducibility, pushing us to tune our process further. Increasingly, customers ask about the lifecycle footprint of each product, forcing us to improve solvent recovery and waste reduction to stay competitive.

    Global supply chain disruptions pushed us to re-examine raw material sourcing and safety stocks. By building long-term relationships with trusted suppliers, we reduce the risk of last-minute substitutions and shortages. Open communication with customers about availability, lead times, and alternatives remains central to long-term partnerships, particularly when downstream manufacturing schedules depend on our punctual delivery.

    Supporting Technical Development with Our Know-How

    We make it a priority to work alongside R&D teams on pilot projects that use 1,4,5,8-Tetrahydroxyanthraquinone in challenging new applications. Our chemists respond quickly to requests for special grades or unusual purity profiles and can advise on solvent compatibility, reactivity, and scaling issues. Case studies shared by customers in the battery and advanced material fields help us improve both process and product, so every trial helps build shared industry knowledge. Over time, these collaborations bring more stability and predictability to supply chains built on specialty chemicals.

    We notice that across sectors—from colorant chemistry to next-generation energy technology—success increasingly depends on close communication and real-world experience, not just published specs. Customers visiting our site or audit our processes often discover incremental improvements that have become standard because of continuous feedback cycles. The result is a chemical product shaped as much by daily manufacturing realities as scientific literature.

    Challenges on the Manufacturing Side

    Technical and regulatory challenges shape every working day. Product consistency relies on equipment calibration, ongoing maintenance, and experienced staff. Over time, machinery drift or operator changes can cause subtle shifts in process reliability, so long-term attention to training and record-keeping is not optional. Global chemicals markets push prices for both raw materials and energy, making efficiency savings even more important. While the tools change—the need to adapt and innovate stays the same.

    Waste management and resource conservation now shape purchasing decisions for many clients. Authorities and customers increasingly ask for data on waste disposal, solvent recycling, and overall environmental impact. By introducing closed-loop solvent systems and reduced processing emissions, we manage to meet these expectations while supporting internal cost reduction targets. Local partnerships for waste processing and resource recovery also reinforce our role in broader industrial sustainability.

    Continuous Improvement: Listening and Learning

    Feedback from end users teaches us more than any textbook. Years ago, overseas shipments in extreme cold damaged pigment performance, so we added thermal protection layers for critical routes during winter. A customer visiting for process validation suggested a change in filter press cycle—something we hadn’t tried before—which now helps ensure less retention of trace impurities. We run cross-departmental meetings to share such stories, recognizing that small insights can make all the difference at scale.

    On occasion, we adapt product offerings to changing regulations or new performance targets. Requests for food or pharmaceutical grade purity drove us to separate production lines and introduce dedicated quality analytics, all based on open dialogue with industry partners. Each adjustment takes time and investment, but it delivers better results for both us and our clients.

    Today’s market emphasizes both chemical performance and traceability. We help customers understand changes in physical appearance, flow properties, and color depth, as these can point to potential improvements across the value chain. Open engagement rewards us with better client loyalty and product success rates, reinforcing the benefit of sharing practical manufacturing knowledge.

    Looking Forward

    Experience as a manufacturer gives a long-term view on both the promise and the challenges associated with 1,4,5,8-Tetrahydroxyanthraquinone. We work every day to keep product quality high, enhance sustainability, and meet changing customer needs. Combining process expertise, responsive customer support, and real-world testing sets our product apart and provides a foundation for new developments. Lessons learned from both success and setbacks help us improve, and drive us to carefully refine each batch to keep pace with industry demands.