Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

1,3-Dimethyl-1H-Pyrazole-5-Carboxamide

    • Product Name 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide
    • Alias Penflufen
    • Einecs 608-503-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    808259

    Chemical Name 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide
    Molecular Formula C6H9N3O
    Molecular Weight 139.16 g/mol
    Cas Number 17265-14-4
    Appearance White to off-white solid
    Melting Point 157-159 °C
    Solubility In Water Slightly soluble
    Purity Typically ≥98%
    Smiles CN1C=NC(C)(C=O)=C1
    Storage Conditions Store at room temperature, keep container tightly closed
    Iupac Name 1,3-dimethyl-1H-pyrazole-5-carboxamide
    Synonyms 1,3-Dimethylpyrazole-5-carboxamide

    As an accredited 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g amber glass bottle with tightly sealed cap, chemical label displaying "1,3-Dimethyl-1H-Pyrazole-5-Carboxamide," purity, and safety information.
    Shipping 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide is typically shipped in tightly sealed, chemical-resistant containers to prevent moisture absorption and contamination. It should be packaged according to regulations for non-hazardous organic compounds and transported in cool, dry conditions. Proper labeling and documentation must accompany the shipment to ensure safe handling and regulatory compliance.
    Storage 1,3-Dimethyl-1H-pyrazole-5-carboxamide should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from direct sunlight and incompatible substances such as strong oxidizers. Avoid sources of ignition and moisture. Properly label the container and ensure access is restricted to trained personnel. Refer to the Safety Data Sheet for specific details and additional precautions.
    Application of 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide

    Applications of 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide in Industrial Manufacturing

    1,3-Dimethyl-1H-Pyrazole-5-Carboxamide is a specialty chemical adopted in multiple high-value industrial segments. Manufactured with consistent quality, it serves as a reagent and intermediate in tightly regulated sectors. Below, we describe its real downstream usage pathways, compliance expectations, processing integrations, and its impact on end product composition and function.

    1. Nitrogen Stabilizer for Urea-Based Fertilizers

    Manufacturers in agricultural input production use this compound as a nitrification inhibitor within granular and liquid urea fertilizer systems. Its molecular design allows effective integration in industrial granulation and coating processes, improving nitrogen retention in crop soil. Industry requirements demand precise dosing and compliance with agricultural chemical residue regulations for global fertilizer products.

    Industry compliance standards

    • EU Fertilising Products Regulation (EU) 2019/1009
    • U.S. EPA Labeling and Tolerance Standards for Nitrification Inhibitors
    • ISO 8157:2015 for Fertilizers and Soil Conditioners
    • China GB/T 23349-2021 for Slow/Controlled Release Fertilizers

    Typical usage ratio

    • 0.5% – 1.5% w/w relative to total urea, adjusted for application method and regional agronomy

    Downstream process integration

    • Blending directly into urea prill mass prior to granulation
    • Applying as part of a coating solution in rotary drum systems for slow-release fertilizers
    • Incorporating via in-line injection in liquid fertilizer production lines

    Final product types

    • Nitrogen-stabilized urea granules
    • Slow-release granular fertilizers for row crops
    • Stabilized liquid fertilizers for drip irrigation systems

    2. Synthesis Intermediate in Crop Protection Active Ingredients

    Downstream agrochemical producers employ this material for selective synthesis of pyrazole-derived pesticides and herbicides. It reacts under controlled conditions to form active moieties required in patent-protected formulations. Production is governed by regulatory dossiers requiring full traceability and residue analysis for agricultural chemicals.

    Industry compliance standards

    • FAO/WHO Specifications for Agricultural Pesticides
    • REACH Registration for Intermediate Chemicals (EC No 1907/2006)
    • Good Manufacturing Practice (GMP) for Active Substance Manufacturing (EU Regulation 2017/625)
    • China GB 2763-2021 on Maximum Residue Limits for Pesticides

    Typical usage ratio

    • Depends on molecular synthesis pathway, typically 1.2–2.0 equivalents as starting substrate per mole of target pyrazole ring structure in batch reactors

    Downstream process integration

    • Input at the heterocycle condensation stage in multi-step batch synthesis
    • Participation in acylation or methylation reactions for functional group modification
    • Integration with continuous flow systems for specialty agrochemical manufacturing

    Final product types

    • Herbicide technical concentrates
    • Fungicidal premixes for cereals and vegetables
    • Insecticidal active substance for formulation export

    3. High-Performance Resin Modifier in Industrial Coatings

    Coatings and composite formulators use this compound to fine-tune resin crosslinking for industrial paints and adhesives, especially in systems requiring enhanced weathering and chemical resistance. It can act as a reactive modifier, adjusting performance parameters of binders used in high-durability coatings for infrastructure and automotive parts. Material traceability and VOC-compliance are critical in this downstream sector.

    Industry compliance standards

    • US EPA Clean Air Act - National VOC Emission Standards for Industrial Surface Coating (40 CFR Part 59)
    • EU Directive 2004/42/EC on Volatile Organic Compounds
    • ISO 12944-5:2018 for Coating Systems for Corrosion Protection of Steel Structures
    • China HJ 2537-2014 on Limits of VOCs in Industrial Coatings

    Typical usage ratio

    • Introduced at 0.2%–1.0% w/w of total resin solids, based on required crosslink density and system reactivity

    Downstream process integration

    • Pre-mixed with polyol or acrylic resins prior to polymerization
    • Added to the binder phase during in-plant blending or in-line mixing before application
    • Used in solvent-borne, high-solids, or powder coating systems

    Final product types

    • Protective epoxies for marine and bridge structures
    • Industrial machinery coatings
    • OEM automotive topcoats
    • Adhesives for electronics assembly

    4. Functional Intermediate for Pharmaceutical Synthesis

    In the pharmaceutical sector, API manufacturers utilize this raw material within select pyrazole-based drug molecule syntheses. Its purity and ISPE-compliant manufacture suit use in GMP-regulated production lines. Downstream synthesis involves condensed steps under well-controlled conditions to meet monograph and regulatory submissions, with release testing for all residuals and related impurities.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF and Ph. Eur. Monograph Standards on Pyrazole Derivatives
    • FDA 21 CFR Part 211 (Current Good Manufacturing Practice in Manufacturing, Processing, Packing, or Holding of Drugs)
    • China Pharmacopoeia (ChP) for active substance registration

    Typical usage ratio

    • Applied in stoichiometric quantities in respect to target intermediate; 1.0–1.5 equivalents adjusted for synthetic yield, not present as excipient in finished dosage

    Downstream process integration

    • Charged during heterocyclic ring formation step in fine chemical synthesis
    • Subjected to purification and crystallization before API isolation
    • Covered by in-process QC for impurity profile and residual solvent analysis

    Final product types

    • Active pharmaceutical ingredients (APIs) for anti-inflammatory drugs
    • Precursors for CNS and cardiovascular medications
    • Registered intermediates for custom synthesis contracts

    5. Laboratory Reagent for Analytical Chemistry and Process Testing

    Accredited laboratories and industrial QC departments adopt this compound for analytical reference and as a derivatization agent in chromatographic and spectrometric methods. Its certified specification assists in trace impurity profiling and calibration tasks during process development or routine batch validation. Robust documentation supports traceability in accredited laboratory environments.

    Industry compliance standards

    • ISO/IEC 17025:2017 Accreditation for Testing and Calibration Laboratories
    • ASTM D1976, E260, and similar protocols for reagent use
    • USP <1225>, <621>, <1226> on Analytical Method Validation
    • GLP (Good Laboratory Practice) compliance as per OECD Documentation

    Typical usage ratio

    • Applied in micromolar to millimolar concentrations as per standard operating procedure, adjusted to instrumental sensitivity and matrix complexity

    Downstream process integration

    • Dissolved in analytical-grade solvents for use in sample derivatization, calibration curve generation, or reference standard testing
    • Integrated into multi-residue pesticide or pharmaceutical analysis workflows
    • Used in sample preparation lines for QC testing in GMP manufacturing

    Final product types

    • Chromatographic reference standards for method validation
    • Internal markers for process control in bulk synthesis plants
    • Analytical kits for contract laboratory services
    Free Quote

    Competitive 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    1,3-Dimethyl-1H-Pyrazole-5-Carboxamide: The Practical Chemistry Behind a Key Industrial Ingredient

    Producing 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide: Insights from the Plant Floor

    On the manufacturing side, 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide has become one of those compounds that really show the bridge between chemistry and everyday applications. Working with this molecule means going beyond theory. Each batch starts with carefully screened raw materials to avoid contamination, because even minor impurities can cause headaches in downstream formulations. The in-house reactors are monitored closely for temperature and pressure since these play big roles in how the final product turns out. Every shift, we watch for the right color, consistency, and filtration profile. Getting these settings right gives a consistent crystalline solid, which cuts way down on delays during quality checks and shipping.

    What stands out in our daily work with this compound is its stability. Once synthesized and purified, 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide holds its structure securely. Shelf-life reports don’t surprise anyone in the lab. Storing and shipping bulk drums has become routine — sealed, moisture-protected, and always labeled with purity results from our most recent HPLC and GC analyses. Consistently meeting target assay specifications — usually well above 98% — comes from strict batch tracking and trained personnel at every step.

    From the Reactor to Industry: How 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide Connects to Real Needs

    Demand for this molecule has followed growth in specialty chemical sectors, especially where it serves as a key functional intermediate in agrochemical and advanced material synthesis. As practitioners, everyone here sees more than a CAS number. In the agrochemical field, 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide forms an important backbone for synthesizing active ingredients that influence crop protection. Time after time, buyers highlight its integration into nitrification inhibitor formulations. These inhibitors slow down the conversion of ammonium to nitrate in soil, which helps farmers keep more nitrogen in the root zone while limiting environmental runoff. Requests for higher-purity material always spike ahead of spring planting seasons, underlining the direct link between our process consistency and the needs at farm level.

    Outside agriculture, development labs in coatings and high-performance polymers test this compound for its compatibility with polyolefins and potential to introduce unique functional groups. Skilled chemists favor this molecule because it tolerates a variety of reaction conditions, including higher temperatures and the presence of typical industrial solvents. Our technical team often works with partners to refine particle size or moisture specifications, reflecting industry trends for precise, reproducible behavior during blending or extrusion.

    Distinguishing Features: What Sets 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide Apart

    Experience on the production line has highlighted traits that differentiate 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide from similar compounds. Its melting point and solubility profile lead to easier handling than less substituted pyrazole derivatives. We rarely see caking or dusting issues during transport or automated unloading. Radiant drying setups and regular maintenance of storage bins help ensure that even the last kilogram in a container matches the first one — this is not always the case with other intermediates in the same family.

    Some customers compare this chemical to 3-methyl-1H-pyrazole-5-carboxamide or unsubstituted pyrazole carboxamides, seeking performance differences in their downstream applications. The extra methyl group on the pyrazole ring shifts reactivity, giving better selectivity in certain condensation or coupling reactions. This can simplify purification steps in the next stage, producing cleaner end products or making scale-up more straightforward. Feedback from customer pilots often points out these practical benefits. Where a competitor’s lot has created delays because of inconsistent melting temperature or tricky filtration, batches from our line have passed without the calls for extra technical support.

    Supporting Consistency and Traceability in Every Batch

    Batch records matter a great deal here. No matter how routine the run, every tank, filter, and dryer is logged from raw charge to sampling and packing. Overhearing a conversation on the plant floor about traceability shows how embedded quality culture has become. Even for a mature product like this, periodic reviews of chromatograms and spectroscopic data lead to tweaks in the purification cycle. Customers have relied on our lot details to convince their regulatory teams of robust supply chain and specification control. Beyond compliance, this level of transparency means faster issue resolution if a downstream formulation needs troubleshooting.

    Over time, we’ve introduced closed-system handling and regular operator training so nobody has to worry about accidental exposure or contamination. Monitoring dust levels, ensuring that transport bags and drums withstand rough handling, and keeping the warehouse at just the right humidity cut down on any chance of degradation. As the industry asks for new types of packaging — lower-weight bags for easy lifting, recyclable liners — we have adapted without loss of chemical purity or consistency.

    Real-World Application Insights: From Start-Up to End-User

    Plant operators and product developers alike notice that 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide works reliably as a core starting point for new inhibitor molecules. Many projects start with a handful of pilot batches before moving to large-scale synthesis. The low content of residual solvents and minimal ash in our process mean that scaled-up reactions tend to behave as predicted. Instead of troubleshooting side reactions or worrying about discoloration, teams concentrate on hitting yield targets and cleaning up downstream steps.

    Talking with technical contacts at fertilizer blenders, the main preference centers on moisture control. They want a flowable powder, one that doesn’t stick or clump during mixing with urea or ammonium-based fertilizers. Our continuous milling and inline drying have made this a non-issue for end-users in different climates. From bagging lines in temperate European warehouses to bulk container handling in humid Asian distribution centers, the compound’s physical form stands up to varying conditions.

    Addressing Industry Challenges: Sustainability, Compliance, and Future Needs

    Growth in global agriculture and pressure to manage nutrient loss mean more attention on the molecules underpinning fertilizer technologies. For anyone in manufacturing, this raises questions about responsible sourcing, waste minimization, and environmental impact from start to finish. Our facility sources precursors with full transparency, avoiding any suppliers with questionable environmental or labor records. Waste streams — everything from wash waters to off-gas — get recycled or treated under strict local standards. Regular audits keep the team sharp and processes up to date.

    Documentation for REACH and national chemical inventories involves regular testing and updates. We provide full regulatory information to buyers seeking reassurance for their compliance checks. The rise in demand for “greener” formulations has prompted pilot runs with recycled solvents and potential bio-based sources of feedstock. Switching to these alternatives calls for strict monitoring, but our teams invest the time and resources to validate that every batch meets long-established standards.

    For product stewardship, packaging upgrades include tamper-evident seals, improved ventilation for bulk containers, and clearly updated hazard labels. Customer feedback loop directly into packaging trials and procedural changes. There’s pride in seeing our chemical move safely through increasingly complex distribution chains — from plant dock through logistic partners and finally into production lines in dozens of countries. This adds another layer of confidence for partners evaluating risk and quality.

    Continuing Innovation: Meeting Tomorrow’s Equipment and Process Requirements

    Innovation isn’t optional for today’s chemical manufacturers. Equipment upgrades drive production capacity, but also help tighten reaction parameters and reduce energy use. For 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide, newer reactor setups have lowered solvent consumption and improved particle morphology. Testing these adjustments happens shoulder-to-shoulder with operators, not just in engineering offices. Our investment in monitoring technology — in-line cameras, near-infrared sensors — catches anomalies early, so a problem never reaches the customer’s site.

    Technical teams work with academic and industry partners, sharing anonymized process data that support faster development cycles for next-generation inhibitors and specialty chemicals. Collaborating in real time accelerates troubleshooting and helps future-proof not just this molecule but related chemical building blocks. The dialogue with users drives us to enhance flow properties, extend shelf life, or tweak residual impurity profiles whenever new regulations or application needs arise.

    Building Long-Term Value Through Experience and Relationships

    Many buyers who started with small-volume evaluation lots have returned year after year for scalable, worry-free sourcing. Nothing substitutes for direct, plant-level experience. Batches of 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide come with institutional knowledge — operators, chemists, and logistics specialists who recognize and preempt the common pitfalls that slow other suppliers down.

    Relationships with downstream blenders, researchers, and industrial scale-up experts mean we often hear about application issues early. This leads to proactive changes, sometimes days or weeks before a trend affects the wider market. Years spent on research partnerships have clarified that responsiveness matters as much as technical quality. Our continued investment in training, HSE compliance, and process improvement has built trust at every link of the supply chain.

    Responding to Market Demands: Agility and Customization

    Markets evolve, and specifications do too. Some sectors want higher-purity lots, tighter particle-size distributions, or exclusive production windows. Experience has taught us the value of flexibility. Dedicated lines supply custom requests without disrupting core production. From same-day document turnaround for logistics to batch-specific custom testing, teams meet these needs in stride.

    Support doesn’t end with delivery trucks leaving our warehouse. Post-shipment technical service fields questions, tracks shipment performance, and relays feedback to batch chemists. This culture minimizes downtime for our customers and cements long-term reliability for production planners in need of dependable chemical intermediates.

    Conclusion: Everyday Chemistry with Broad Impact

    For chemists, process engineers, and buyers alike, 1,3-Dimethyl-1H-Pyrazole-5-Carboxamide stands out on more than purity or compliance. Behind every ton is a practical story — routine work, troubleshooting, and commitment to predictable performance. Experience on the ground helps shape what leaves the gate: a stable compound ready to support the evolving needs of agriculture, materials science, and specialty synthesis. As the industry shifts, this is one product that continues to earn its place by linking careful production with real-world results.