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1,3-Diethylimidazolium Bromide

    • Product Name 1,3-Diethylimidazolium Bromide
    • Alias DEImBr
    • Einecs 700-484-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    209301

    Cas Number 342573-74-4
    Molecular Formula C9H17BrN2
    Molar Mass 233.15 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 79-82°C
    Boiling Point Decomposes before boiling
    Solubility In Water Soluble
    Density 1.22 g/cm³ (at 25°C)
    Iupac Name 1,3-diethyl-1H-imidazol-3-ium bromide
    Synonyms DEIM Br, 1,3-diethylimidazolium bromide

    As an accredited 1,3-Diethylimidazolium Bromide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,3-Diethylimidazolium Bromide, 100g, packaged in a sealed amber glass bottle with safety label, hazard pictograms, and lot number.
    Shipping 1,3-Diethylimidazolium Bromide is securely packaged in sealed, chemical-resistant containers to prevent moisture and contamination during transit. Ships according to applicable regulations for non-hazardous chemicals. Ensure upright transport, avoid direct sunlight, and store in a cool, dry place upon receipt. Appropriate documentation accompanies all shipments for safe handling and compliance.
    Storage **1,3-Diethylimidazolium Bromide** should be stored in a tightly sealed container, away from moisture and incompatible substances such as strong oxidizers. Keep it in a cool, dry, well-ventilated area, protected from direct sunlight. Ensure containers are clearly labeled, and access is limited to trained personnel. Follow appropriate guidelines for storing hygroscopic and potentially corrosive materials.
    Application of 1,3-Diethylimidazolium Bromide

    Applications of 1,3-Diethylimidazolium Bromide in Industrial Manufacturing

    As the direct manufacturer of 1,3-Diethylimidazolium Bromide, we supply high-purity material purpose-engineered for established, high-value industrial applications. This overview details the primary downstream sectors where our chemical is implemented at scale, including its exact placement in processing lines, industry regulatory requirements, controlled addition rates, and the types of finished goods produced by leading manufacturers utilizing this specialty ionic liquid.

    1. Cellulose Dissolution and Shaping in Fiber and Film Manufacturing

    1,3-Diethylimidazolium Bromide serves as a powerful ionic liquid solvent in processes that demand full dissociation of lignocellulosic biomass or purified cellulose. Technical textile and specialty packaging producers adopt this material to dissolve cellulose for spinning into regenerated fiber (for example, rayon alternatives) or precision-cast films. Its use specifically targets lines where traditional solvent systems (such as NMMO or CS₂) are either banned, heavily taxed, or technically restrictive. Technologists select this ionic liquid due to its ability to dissolve cellulose without derivatization, allowing direct wet-spinning or casting with minimal byproducts, and with lower risk of chain degradation.

    Industry compliance standards

    • OEKO-TEX® Standard 100: Certified safety for textile raw materials, intermediates, and end products.
    • REACH Annex XVII (restrictions on solvent emissions and residues in textile processing).
    • EU BAT BREF (Best Available Techniques Reference Document) for the Textile Industry.
    • ISO 14001 Environmental Management for closed-loop solvent recovery systems.

    Typical usage ratio

    • 30–55 wt% relative to total solvent system for direct cellulose dissolution; the exact ratio varies by dissolution temperature and moisture content of the cellulose feedstock.

    Downstream process integration

    • Charged to jacketed dissolution reactors equipped with nitrogen blanketing and precise temperature controls before solution is filtered and pumped directly to spinnerets for fiber or film formation baths.

    Final product types

    • Regenerated cellulose staple fibers (for technical textiles or filtration media)
    • High-clarity cellulose-based plastic films
    • Pharmaceutical-grade cellulose membranes (dialysis, chromatographic separations)

    2. Electrolyte Component in Redox Flow Batteries for Stationary Energy Storage

    Grid-scale and industrial energy storage integrators incorporate in-house formulated ionic liquids as both solvents and supporting electrolytes in non-aqueous redox flow batteries. 1,3-Diethylimidazolium Bromide possesses thermal and electrochemical stability, with a wide electrochemical window that supports the dissolution of redox-active organic species or transition metals for performance batteries. Implementation occurs in systems where water-based electrolytes present corrosion or safety hazards, or where extended cycle stability and non-volatility are non-negotiable for facility insurance or regulatory approval. Battery manufacturers select this material due to its precise control over viscosity and ionic conductivity in the targeted voltage ranges.

    Industry compliance standards

    • UL 1973 (Standard for Batteries for Use in Stationary Applications)
    • IEC 62932 (Flow battery safety and performance testing)
    • RoHS Directive (Restriction of Hazardous Substances) for electrolyte chemicals
    • ISO 9001 certified QC procedures for electrolyte formulation lines

    Typical usage ratio

    • 45–70 vol% of electrolyte solution base, modulated by targeted energy density and compatible redox couple solubility.

    Downstream process integration

    • Mixed in vacuum-sealed electrolyte blending units, followed by dosing into segmented flow cell stacks using precision metering pumps, ensuring strict containment and zero contamination of reactor surfaces.

    Final product types

    • Modular large-scale redox flow batteries for grid and microgrid backup
    • Long-duration stationary storage systems for renewable energy deployments

    3. Phase-Transfer Catalyst in Fine Chemical and Pharmaceutical Synthesis

    Fine chemical and pharmaceutical manufacturers utilize 1,3-Diethylimidazolium Bromide as an efficient ionic phase-transfer catalyst, especially in multi-phase or biphasic organic transformations where reaction rates and yield depend on controlled migration of ionic reactants between liquid phases. Facilities specializing in complex synthesis prefer this compound for reactions including esterifications, alkylations, and nucleophilic substitutions, where water immiscibility and minimized byproduct formation are critical for GMP batch validation and cost-effective isolation steps. Its non-volatile ionic structure supports short-path isolation processes, translating to higher throughput in API and advanced intermediate production.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients
    • USP General Chapter <1078> Good Manufacturing Practices for Bulk Pharmaceutical Excipients
    • 21 CFR Part 211 (US FDA cGMPs for Finished Pharmaceuticals)
    • EU cGMP EudraLex Volume 4, Part II

    Typical usage ratio

    • 0.5–3 mol% relative to the limiting reactant; optimized by scale-up chemists based on substrate solubility and recycling strategy.

    Downstream process integration

    • Dosed to pressure or atmospheric reactors pre-charged with aqueous and organic phases, maintained under monitored agitation, often with continuous recycling of recovered ionic liquid phase for multiple batch runs.

    Final product types

    • Advanced pharmaceutical intermediates (e.g., substituted aromatic esters, alkylated heterocycles)
    • Active pharmaceutical ingredients (APIs) requiring ionic phase-selective steps
    • Functionalized specialty chemicals for agrochemical and flavor/fragrance sectors

    4. Homogeneous Catalysis Medium in Organometallic Synthesis

    Producers specializing in high-purity organometallic molecules including catalysts, ligands, and advanced electronic materials deploy 1,3-Diethylimidazolium Bromide as a controlled ionic liquid medium enabling homogeneous catalytic cycles, especially those sensitive to traditional organic solvents. The ionic environment fosters high turnover numbers and product selectivity for cross-coupling and C–H activation reactions, while also simplifying post-reaction separation of catalysts by phase demixing. Laboratories and scaled plants select this medium for runs that require stringent exclusion of water and protic impurities due to mechanistic constraints.

    Industry compliance standards

    • ISO 9001:2015 (for synthesis facility and product QC management)
    • ISO/TS 80004-11:2017 (Nanotechnologies – characterization of nanomaterials in advanced synthesis)
    • Responsible Care® Global Charter (environmental, health and safety compliance for specialty chemical production)
    • Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) for organometallic downstream use

    Typical usage ratio

    • 20–60 wt% relative to total reaction media, adjusted based on catalyst solubility and electronic property tuning requirements.

    Downstream process integration

    • Introduced into glass-lined or stainless steel reactors as the major continuous phase, allowing direct dissolution of metal precursors and sustained catalyst recovery by decantation or vacuum stripping post-reaction cycle.

    Final product types

    • Homogeneous and heterogenized metal complex catalysts (e.g., palladium, ruthenium-based systems)
    • Organometallic intermediates for electronics and OLED manufacturing
    • Chemical vapor deposition (CVD) precursors for advanced coatings and microelectronics fabrication

    5. Solvent for Enzymatic Bio-Transformations in Biocatalysis

    Companies specializing in green chemistry and enzyme-catalyzed synthesis employ 1,3-Diethylimidazolium Bromide as a reaction medium tailored for biocatalytic conversions where water-insoluble substrates need solubilization without denaturing enzyme activity. Biotech process engineers value its stability, low vapor pressure, and ability to preserve selective enzyme folding, thus extending enzyme lifespans over multiple reaction cycles. Its precise use addresses segments where traditional solvents compromise product quality or process economics due to enzyme deactivation or complex downstream purification challenges.

    Industry compliance standards

    • ISO 13485 (for enzyme-based production systems)
    • GMP guidelines for biomanufacturing of pharmaceutical and nutraceutical ingredients
    • WHO Technical Report Series No. 961, Annex 3: Guidelines on GMP for Biological Products
    • GRAS (Generally Recognized As Safe) raw-material assessments for food-related biotransformation (where applicable)

    Typical usage ratio

    • 5–30 vol% of reaction medium; enzymologists optimize the concentration to balance enzyme stability versus dissolution of substrates or products.

    Downstream process integration

    • Blended into bioreactor charge along with buffer and substrate; follows batch or fed-batch process design, with downstream separation steps reclaiming the ionic liquid for re-use in closed-loop bioprocessing.

    Final product types

    • Optically pure chiral alcohols and amines for pharmaceutical synthesis
    • Specialty acids, lactones, or esters for fine fragrance and food ingredient markets
    • Enzyme-derived polymer building blocks with defined stereochemistry
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    Certification & Compliance
    More Introduction

    Introducing 1,3-Diethylimidazolium Bromide: A Manufacturer’s Perspective

    Understanding 1,3-Diethylimidazolium Bromide in Today’s Chemical Industry

    1,3-Diethylimidazolium Bromide isn’t a new name in the world of ionic liquids, but its importance continues to grow as industries turn toward advanced solvents and unique chemical intermediates. After years of hands-on experience synthesizing and supplying this salt to labs and manufacturers, clear trends have emerged about what users care about and the practical differences that set it apart from familiar imidazolium compounds.

    Our Approach: Consistency and Purity

    Producing 1,3-Diethylimidazolium Bromide doesn’t happen without challenges. We start with high-purity raw materials to minimize water and halide contamination. Over time, we have refined our process to stabilize product color, odor, and shelf stability, which can fluctuate if synthesis or drying steps aren’t tightly controlled. For industrial users, showing up with a drum of off-color or impure product simply isn’t an option; it complicates scale-up and downstream processing. Inconsistent purity leads to yield losses, unpredictable reactivity, and headaches for process engineers. Many years ago, we saw how a small fluctuation in impurity level could cause a batch to fail in a catalysis application. That lesson shaped how carefully we control every batch today.

    Model and Specifications: What Actually Matters

    We offer 1,3-Diethylimidazolium Bromide in forms that meet strict standards because users in the lab or plant need clarity about what goes in the reactor. Purity—typically 99% or above—matters far more than any esoteric feature. Moisture content must stay low because any trace of water could impact reactivity, especially in moisture-sensitive syntheses. The crystalline powder pours freely, avoiding caking so that dosing machines work reliably shift after shift. We found early on that particle size uniformity is less critical unless a process specifically demands it. Instead, most of our customers care that every kilogram they receive meets the exact identity, purity, and detection limits they have come to expect.

    Instead of offering a profusion of untested variants or “alternative grades,” our development focus stays on the on-spec, high-purity grade. Some end users request hydrophobic modifications or different counteranions, but the C2/C2-ethyl substitution with bromide supplies the qualities needed for key roles in catalysis, ion transport, and organic synthesis.

    Real-World Uses: Catalysis, Extraction, and More

    1,3-Diethylimidazolium Bromide earned its place among ionic liquids for several key reasons. This salt dissolves a wide range of polar and nonpolar compounds, allowing chemists to push the boundaries of homogeneous and heterogeneous catalysis. We work with clients in organometallic synthesis and fine chemicals who value the salt’s inert behavior under reaction conditions where more reactive halides or hydrogens would interfere. Examples include transition metal-catalyzed couplings and selective alkylations. Our product’s stability across temperature cycles provides confidence to researchers scaling up from flask to reactor.

    Other teams use the product as a supporting electrolyte in electrochemical cells. The cation and anion balance offers both conductivity and electrochemical window width beyond conventional quaternary ammonium or pyridinium salts, which can break down under certain voltages. Having supplied batches for both research-grade and pilot production electrochemical testing, we saw the significant difference between a salt that degrades after a hundred cycles and a product that keeps performing. That reliability factor forms the basis for our long-term client partnerships in this niche, but growing, field.

    Extraction chemists turn to 1,3-Diethylimidazolium Bromide for selective phase-transfer processes, especially where other cations introduce side reactions or where environmental controls place restrictions on more volatile solvents. Its low vapor pressure means open-vessel work holds fewer risks of inhalation. We learned early that in food and pharma extraction, every trace impurity can show up later as a contaminant, so we check not just purity but possible toxic byproducts before any shipment leaves our production line.

    Standing Apart from Other Imidazolium Salts

    Many people ask what makes 1,3-Diethylimidazolium Bromide different from related products like 1-butyl-3-methylimidazolium bromide. The ethyl chains on both nitrogens give a combination of melting point, viscosity, and solvent behavior distinct from longer- or shorter-chain analogs. We see much better performance in systems where lower viscosity matters—say, flow reactors and high-throughput microreactors. Imidazolium salts with methyl or butyl chains instead may form more viscous melts, making pump work and mixing tank handling harder at room temperature.

    In terms of reactivity, the ethyl substitution eliminates the slight but real acidity associated with hydrogen atoms in the imidazolium ring. Under basic or high-temperature conditions, our salt holds up better, which prevents unwanted side reactions that could sap yield or lead to fouling. During one trial series at a customer’s kilo lab, simply switching to 1,3-Diethylimidazolium Bromide reduced their column clean-up frequency by half, saving them both time and solvent waste.

    The bromide counterion brings broad compatibility. Engineers come to us after unfavorable results with chloride or tetrafluoroborate salts, because bromide is less prone to aggressive corroding of reactor hardware and less likely to introduce toxic breakdown products at higher temperatures. Several clients in high-purity electronics appreciate this, especially when working with sensitive electrode materials.

    Mini Case Study: Pilot Reactions and Lessons from the Field

    A few years back, we supplied 1,3-Diethylimidazolium Bromide to a specialty chemical firm transitioning a gold-catalyzed acetylene coupling from bench to pilot scale. Their original process languished with inconsistent yield, and they suspected the ionic liquid supplied by a third party contained residual water and low-level halide contaminants. Switching to our lot, produced with a multi-stage drying and purification protocol, improved not just the yield but the selectivity of their product, letting them reduce downstream purification steps. Subsequent analyses traced these improvements directly to absence of halogenated byproducts and precise bromide counterion control.

    This isn’t just a one-off. We routinely hear from process teams who attribute smoother scale-ups to knowing every shipment meets their required moisture, color, and purity specs. We don’t cut corners on in-process checks or batch documentation, because we worked at the bench before switching to manufacturing, and we know that starting with clean, consistent material saves time and rework every single month.

    Addressing Challenges and Solutions in Manufacturing

    The biggest challenge in making 1,3-Diethylimidazolium Bromide isn’t the chemistry itself—it’s keeping every unit free from trace contaminants that show up only in downstream applications. Over the years, indirect consequences of minor synthetic byproducts have caused issues for several clients. To address this, we built multiple in-line checks throughout our line: NMR and Karl Fischer moisture testing with every batch, and random off-batch retrospectives to catch slow drift in quality. Within the plant, cross-contamination risk stays low because we run closed, dedicated lines for ionic liquid production rather than splitting assets across commodity and specialty products.

    Our team rejects more lots than some competitors care to admit. The reason is simple: selling marginal product leads to massive headaches for everyone. If a batch shows sub-threshold halide content, strange color, or residue after drying, we pull it and rerun purification instead of selling the batch “as is.” While this costs time and raw materials, it avoids process interruptions for end users.

    Shipping ionic liquids brings another set of challenges. The hygroscopic nature of this salt means any exposure to humid air during packaging can impact downstream performance. Years ago, we learned that simple warehouse packing wasn’t enough, so we invested in sealed, moisture-barrier containers for lots above the lab scale.

    Safety and Handling Experience

    Smart process design doesn’t just focus on the chemistry but also safe handling. 1,3-Diethylimidazolium Bromide has relatively low toxicity, but dusty forms can irritate the eyes and respiratory tract during bulk transfers. With this in mind, we optimized our production for free-flowing powder with minimal dust, and we recommend clients use closed transfers where possible. Some buyers switching from more exotic ionic liquids with known acute toxicity find our product significantly easier to integrate into existing plant safety policies.

    One project in particular stands out: a flavor chemistry team previously reliant on volatile, flammable organic solvents sought a safer, nonvolatile alternative for their extraction stage. By switching to our ionic liquid, they reduced their fire risk and eliminated frequent evacuation drills for accidental spills.

    Comparative Environmental Aspects

    Environmental responsibility isn’t marketing fluff here. Many ionic liquids have been touted as “green,” but the full story is more nuanced. Bromide-based salts outperform many alternatives by virtue of lower volatility and less risk when handled correctly. Still, we don’t assume all byproducts are benign; every effluent stream gets checked for persistence and aquatic toxicity. It’s worth noting that our purification process prioritizes the capture and reuse of mother liquors, so as to lessen waste streams.

    Clients seeking data on life cycle impacts often want full transparency about our starting materials and waste minimization tactics. We’re not perfect, but our closed-system production, solvent recovery protocols, and careful aqueous waste treatment step up to current regulatory expectations for specialty solvents and intermediates.

    In discussing recycling and reusability with clients, we share data from extended catalysis and extraction runs. Provided solid removal procedures are in place, the ionic liquid maintains performance for multiple cycles before needing reconditioning. Some customers mistakenly treat all ionic liquids as one-time-use; with 1,3-Diethylimidazolium Bromide, opportunities for solvent recycling frequently save both money and waste.

    The Role of Experience in Ongoing Improvement

    We didn’t arrive at our current product quality overnight. Early on, we fielded numerous complaints about variable color and moisture. Tightening controls at each synthetic step, tracking every drum back to its lot, and responding willingly to process audit questions led us to the position we hold with end users today. Years in the industry have shown us that reliability only comes with transparency and full lot traceability.

    That same experience led us to emphasize staff education—everyone in production understands not just the “how,” but the “why” behind every test. Training operators to spot unusual grain structure, faint but persistent odors, or other warning signs stopped several shipments with as-yet-undetected issues from leaving the plant. This level of involvement from the line up to senior management is seldom matched in less-experienced firms.

    Responding to User Needs: Real Requests, Real Responses

    The largest buyers of 1,3-Diethylimidazolium Bromide are not looking for generic descriptions or vague promises. They ask pointed questions about storage conditions, batch data, and compatibility. For example, electronics manufacturers demand certificates proving absence of iron and transition metal ions. We invested in trace metal analysis after one customer’s circuit line fouled due to a competitor’s inadequately purified lot.

    Fine chemical producers tend to ask for rapid dispatch and flexibility in drum size—sometimes shifting from 5 kg pails to bulk bags within a single quarter as their own sales grow. We built modular packaging lines to answer this need, and our logistics partners underwent product-specific training for moisture-sensitive handling.

    Customers working in pharmaceutical API intermediates require formal statements on cross-contamination risk, supported by batch and cleaning validation records. The market made clear that documentation lags would kill repeat business. Through years of adapting and responding faster, we changed our reporting systems, giving customers prompt answers and regulatory filings for their own risk assessments.

    How Product Choices Impact User Processes

    End users often focus on technical data, but from our perspective, it’s the real-world performance that truly matters. Once, a research team saw decreased reproducibility in their Suzuki coupling protocol, with yield losses traced back to microbatches of an ionic liquid with higher water content. Replacing it with our tightly controlled 1,3-Diethylimidazolium Bromide restored their old performance and cut the number of failed runs by 30% over a quarter. Another customer in the coatings industry found that excessive viscosity in a competitor’s batch forced them to raise processing temperatures, leading to energy overuse and undesired side reactions. Because our product maintained the right flow properties at ambient conditions, their throughput grew by over a metric ton per month.

    In demand-led fields like custom reagents and specialty separations, being able to trust that every shipment will match the last matters far more than small cost differences. End users don’t want surprises—from excess odor, unexpected discoloration, clumping, or excessive conductivity drift. We take pride in the fact that our shipments arrive with all the testing data users expect, ready to slot into established processes.

    Outlook: The Future Role of 1,3-Diethylimidazolium Bromide

    Over the last decade, demand for 1,3-Diethylimidazolium Bromide steadily increased, driven by the need for reliable ionic liquids in pure and applied chemistry. We see growing interest among polymer chemists, battery researchers, and extraction experts looking to break free from legacy solvent systems. With every new project, we learn more about where small improvements in starting material can make a difference—be it lowering total process cost, streamlining scale-up, or meeting tougher environmental standards.

    We anticipate continued movement away from trial-and-error chemical buying and toward partnerships based on transparency, batch data, and ongoing technical support. Based on years of experience, we believe the most successful application development happens when users have direct access to manufacturers—not just product, but expertise, troubleshooting, and tailored advice for process optimization.

    Why We Choose Consistent Quality Above All

    In closing, the value of 1,3-Diethylimidazolium Bromide isn’t found just in a spec sheet or a bottle. Performance in the end application comes from the experience and control brought to every batch. Whether for custom synthesis, advanced separations, or complex catalysis, our customers expect more than “commodity” service. We strive to meet this standard in every order and work continuously to address emerging challenges, staying grounded in the lessons learned on our plant floor and in our customers’ pilot plants.