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1,3-Diethoxy-2-Propanol

    • Product Name 1,3-Diethoxy-2-Propanol
    • Alias 1,1-Diethoxy-2-hydroxypropane
    • Einecs 209-700-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    194622

    Cas Number 14797-42-7
    Molecular Formula C7H16O3
    Molar Mass 148.20 g/mol
    Appearance Colorless liquid
    Density 0.917 g/cm³
    Boiling Point 176-178 °C
    Melting Point -60 °C (approximate)
    Refractive Index 1.412-1.414
    Flash Point 66 °C (closed cup)
    Solubility In Water Moderate

    As an accredited 1,3-Diethoxy-2-Propanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,3-Diethoxy-2-Propanol is supplied in a 500 mL amber glass bottle with tamper-evident cap and hazard labeling.
    Shipping 1,3-Diethoxy-2-Propanol is shipped in tightly sealed containers, typically made of high-density polyethylene or glass, to prevent leaks and contamination. It should be transported in compliance with local, national, and international regulations, kept away from heat sources and incompatible materials, and protected from physical damage during transit.
    Storage 1,3-Diethoxy-2-Propanol should be stored in a cool, dry, and well-ventilated area, in tightly sealed containers away from direct sunlight, heat sources, and incompatible materials such as strong oxidizers or acids. Containers must be clearly labeled, kept upright to prevent leaks, and protected from physical damage. Store away from ignition sources and ensure appropriate spill containment measures are in place.
    Application of 1,3-Diethoxy-2-Propanol

    Applications of 1,3-Diethoxy-2-Propanol in Industrial Manufacturing

    1,3-Diethoxy-2-Propanol serves specialized functions across multiple industrial sectors due to its distinct molecular structure and chemical reactivity. As a direct manufacturer, we supply this intermediate to customers operating in coatings, polymer modification, specialty solvents, electronic materials, and pharmaceutical intermediates, each requiring strict technical and compliance procedures for integration.

    1. Alkyd Resin Modification for Industrial Coatings

    Formulators in industrial coatings use 1,3-Diethoxy-2-Propanol as a chain modifier in alkyd resin systems to improve flexibility, gloss retention, and weather resistance. Its ether functionality allows for controlled molecular branching without introducing excess hydrophilicity, supporting stable emulsions in both solvent-based and high solids systems. The raw material enters the polycondensation phase after the initial alcoholysis step, with close monitoring of reaction temperatures and stoichiometry. Final coatings achieve enhanced film formation and extended outdoor service life, meeting regulatory and performance requirements for automotive and metal protection applications.

    Industry compliance standards

    • US EPA 40 CFR Part 63 – NESHAP for Miscellaneous Coating Manufacturing
    • EU REACH Regulation (EC) No 1907/2006
    • ASTM D3023 – Standard Practice for Determination of Resistance of Coatings
    • ISO 9001:2015 for process quality management

    Typical usage ratio

    • 2–8% of total resin solids by weight, adjusted based on desired resin flexibility and gloss; lower end for rigid coatings, higher for flexible applications

    Downstream process integration

    • Incorporated post-glycerolysis during polyesterification; added after esterification catalyst charge, controlling rate to avoid side reactions

    Final product types

    • Automotive topcoats
    • Heavy-duty industrial enamels
    • Architectural alkyd paints
    • Corrosion-resistant metal finishes

    2. Additive for Polyurethane Flexible Foam Production

    Flexible polyurethane manufacturers utilize 1,3-Diethoxy-2-Propanol as a reactive polyol blend component to influence open-cell structure, airflow, and softness. The compound's diethoxy substitution offers controlled reactivity when balancing polyester polyols and isocyanates. By adjusting its loading, foam producers fine-tune curing rates and mechanical resilience for furniture, bedding, and acoustic insulation. The additive enters the mixing stage before prepolymer formation, where precision dosing is monitored to prevent excess crosslinking.

    Industry compliance standards

    • ANSI/BIFMA X7.1 – Standard for Furniture Emissions
    • OEKO-TEX Standard 100 (polyurethane articles)
    • ISO 16000-9 – Indoor Air Emission Test for Construction Materials
    • EU Polyurethane Foam Regulation (EU) 2019/1021

    Typical usage ratio

    • 3–12 parts per hundred polyol (php); precise ratio selected by foam density and targeted compressive strength

    Downstream process integration

    • Blended with base polyol stream before addition of isocyanate and catalysts; integrated via high-shear mixers for uniform cell structure

    Final product types

    • Flexible furniture foam
    • Premium bedding materials
    • Sound-absorbing foam panels
    • Cushioning for automotive seating

    3. Intermediate for Active Pharmaceutical Ingredient Synthesis

    Pharmaceutical manufacturers process 1,3-Diethoxy-2-Propanol as a masked hydroxyalkylating agent, supporting formation of N-alkyl or O-alkyl intermediates during multi-step API synthesis. Its acetal groups protect hydroxyl functionality through harsh reaction conditions and can be selectively hydrolyzed to liberate the diol at a controlled stage. The material is introduced during the alkylation or protection phase, and removed under acidic hydrolysis in downstream operations. This enables synthesis pathways for specialty CNS and cardiovascular actives that require temporal functional group control.

    Industry compliance standards

    • ICH Q7 – Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP–NF monograph applicable to target APIs
    • Chinese Pharmacopoeia (if used in China-bound drug synthesis)
    • FDA 21 CFR Part 211 – cGMP for Finished Pharmaceuticals

    Typical usage ratio

    • 0.5–1.2 molar equivalents relative to target intermediate, contingent on stoichiometric requirements of specific API route

    Downstream process integration

    • Charged into reactor during intermediate protection or alkylation; most commonly deprotected in later synthetic stages via acid treatment

    Final product types

    • Small-molecule CNS drugs
    • Cardiovascular intermediates
    • Non-cytotoxic oral solid APIs
    • Specialty fine chemicals for pharma research

    4. Solvent and Anti-Blocking Agent in Photoresist Formulations

    Electronic materials manufacturers integrate 1,3-Diethoxy-2-Propanol as a co-solvent and anti-blocking additive in the formulation of advanced photoresists for semiconductor lithography. The compound imparts a controlled evaporation rate and supports homogeneous dissolution of resins and sensitizers during solution preparation. Process engineers introduce the raw material in the upstream resin dissolution stage, dynamically adjusting the blend to match viscosity, film thickness, and drying profiles required for sub-micron patterning. Outcome stability relies on tight control of solvent ratios through quality management protocols.

    Industry compliance standards

    • SEMI S2 – Environmental, Health, and Safety Guideline for Semiconductor Manufacturing Equipment
    • RoHS Directive 2011/65/EU
    • IEC 62474 – Material Declaration for Electrical and Electronic Products
    • ISO 14644 – Cleanroom Standards

    Typical usage ratio

    • 5–15% by weight of total solvent blend; adjusted based on resin solubility and target spin-coating thickness

    Downstream process integration

    • Added to solvent package during resin pre-mix; subject to vacuum filtration and metering before spin coating on silicon wafers

    Final product types

    • Positive and negative photoresists
    • Advanced IC fabrication resins
    • Color filter materials for flat panel displays
    • MEMS photolithography coatings

    5. Modifier in High-Performance Adhesive Formulations

    Producers of high-performance adhesives use 1,3-Diethoxy-2-Propanol as a reactive diluent in polyurethane and epoxy-based systems, balancing viscosity and crosslink structure for improved spreadability and adhesion to metal, glass, and composites. The additive is introduced during resin blending, facilitating premix homogenization prior to catalyst or hardener addition. Through stoichiometric control, manufacturers tailor mechanical properties to specific shear and peel strength targets required for advanced industrial assembly and lamination workflows.

    Industry compliance standards

    • ISO 4587 – Adhesives – Determination of Tensile Lap-Shear Strength
    • ASTM D1002 – Standard Test Method for Metal-to-Metal Bond Shear
    • UL 746C – Standard for Polymeric Adhesive Materials
    • REACH compliance for chemical safety

    Typical usage ratio

    • 4–10% by resin weight; modified based on working time and application viscosity requirements

    Downstream process integration

    • Premixed with liquid resin under controlled shear; final blend proceeds to static mixing and dispensing lines before substrate application

    Final product types

    • Structural adhesives for automotive bonding
    • Glass-to-metal sealants
    • Panel lamination adhesives
    • Electronic device assembly adhesives
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    Certification & Compliance
    More Introduction

    1,3-Diethoxy-2-Propanol: Reliable Performance for Precise Chemical Applications

    Careful Synthesis, Focused Innovation

    Years spent refining synthetic routes have shaped our batch production process for 1,3-Diethoxy-2-Propanol. Our chemists select high purity raw materials and manage reaction conditions using real-time monitoring. Any deviation runs the risk of side reactions that can increase impurities. By providing consistent temperature and pressure controls, we hold the line on batch uniformity. Each drum that leaves our facility represents a collaborative effort—maintenance crews looking after distillation equipment, analytical teams double-checking data, and hands-on operators who know their valves and lines by heart.

    We have adapted the manufacturing approach to maintain tight control on the ethoxylation steps and the downstream purification. Our well-trained operators minimize residual by-products by keeping column reflux ratios steady. On every run, the team draws samples at precise intervals and cross-references gas chromatographs against the previous lots. This daily discipline pays off in a cleaner product profile, with reproducible performance from drum to drum.

    Model and Specifications

    In practice, our 1,3-Diethoxy-2-Propanol is identified by its molecular structure—C7H16O3. Analytical pure grade emerges as a clear liquid, almost odorless, with a boiling point that sits comfortably above room temperature but below the point where degradation might occur. Water content never exceeds our internal threshold, since residual water often causes downstream hydrolysis in resin or pharma applications. Every tank undergoes Karl Fischer titration as part of final sign-off.

    Batch certifications include baseline purity by GC, a profile for secondary alcohols, and a residue after evaporation test. These data points come from long experience with customers who expect zero surprises across production cycles. Small differences in impurity levels matter—a quality slip can mean lost yield or discoloration downstream, and we address these before product release, not after.

    Applications in Real-World Processes

    Most buyers use 1,3-Diethoxy-2-Propanol for two main reasons: its distinct reactivity and its solvency for specialized resins or intermediates. In alkyd resin manufacturing, this compound fits the bill as a reactive diluent. Its two ethoxy groups give formulators a way to balance solubility with chain flexibility. Epoxy chemists prefer it when looking for thinner viscosity and lower exotherms during cure, since bulkier glycol ethers sometimes drive the reaction too fast or create more unwanted side products.

    Pharmaceutical researchers claim it as a synthetic intermediate. The molecule provides a controlled path to generate protected alcohol functionalities. In many laboratories, our product helps shield reactive sites, letting chemists run longer multi-step syntheses. When the time comes, gentle hydrolysis peels away the ethoxy groups, revealing the primary structure underneath. The purity and color clarity of our diethoxypropanol supports smooth reaction workups and cleaner purification steps on scale-up.

    Industrial cleaners sometimes use it for its ability to promote wetting without being overly volatile. Its boiling point gives a longer flash-off time than typical glycol ethers, reducing flammability risks for line operators. With growing focus on operator safety, more clients seek chemicals that balance process efficiency and occupational health.

    Differences From Similar Glycol Ethers and Alcohols

    As a manufacturer, we know side-by-side comparisons drive many procurement choices. Our teams have tracked competitors’ grades, measured their impurity levels, and observed their downstream performance. 1,3-Diethoxy-2-Propanol distinguishes itself in both structure and outcome versus other glycol ethers.

    Most competitors offer monoethoxy analogs or simple 1,2-diols. The extra ethoxy group in our molecule changes both polarity and chemical resilience—it resists rapid hydrolysis under mild acidic or basic conditions. This results in greater formulation latitude for chemists who need longer processing windows. We hear frequently from coating formulators that ethoxylated alcohols with fewer ethoxy groups tend to split apart in storage or under strong sunlight. Our product maintains its stability, helping avoid those headaches.

    We also note a significant difference in volatility and solvency compared to traditional alcohols like n-propanol or 1,2-propanediol. Production teams observe that our diethoxypropanol evaporates slower, cutting down worker exposure during mixing. That slower evaporation widens the working window for resin applications. Adhesive makers have told us their lines run without frequent stoppages due to gelling, a problem that often crops up with faster-evaporating co-solvents.

    Toxicologists within our operation track both published and in-house exposure data. Available evidence points to lower acute toxicity compared to some high-volatility glycols. We adjust our recommendations based on workplace air monitoring at customer facilities where processes are not enclosed.

    Process Reliability: Roots in Daily Practice

    We run multiple small-scale and pilot plants, feeding the main commercial units that meet the bulk of demand. Our master batches feed smaller production runs for specialty clients. Years of tuning reaction conditions show that even minor temperature shifts change impurity spectra. Crews monitor and adjust parameters mid-run if sensors pick up unexpected deviations.

    Our in-house lab maintains traditions carried forward by the founding chemists—documenting each synthesis lot, noting how pH drifts or color changes signal process drift. Through thick and thin, this habit of meticulous note-taking sets the foundation for high quality. Troubleshooting emerges as much from operator experience as from modern analytics. A process technician might spot a slight haze in a sight glass or catch a faint odor before QA flags an issue.

    Raw material quality checks come first. If an incoming ethanol shipment smells even faintly off, blending is paused until further testing. Conditioning and inerting storage tanks ensures no water sneaks into the process—because water traces mean more work at the distillation stage. Small investments in switching valves or improving pump seals return larger gains in final product reliability.

    Customer Experience Shapes Our Focus

    Decades of partnership with resin and coatings formulators reveal patterns invisible to the casual observer. Clients teach us that inconsistent viscosity means more scrap, rework, and cost. Our teams know their pain points, so they prioritize homogeneity and batch repeatability. Quality audits at customer operations have led us to adopt more frequent in-process checks.

    When a group of adhesives makers flagged gel formation on their lines, technical service engineers traced the issue to a trace contaminant—residual potassium. In-house changes to distillation columns, matched with closer monitoring of process lines, dropped contamination below detection. Understanding difficulties in end-user application prompts new investment in storage, analytics, and waste minimization.

    Smaller resin plants value custom packaging that supports safer and more accurate transfers. Working from bulk ISO-tanks down to 200-liter drums, teams document transfers and apply tamper-evident seals, since spilled product creates extra risks and losses for small-batch operators. Every detail, from drum lot tracking to barcode labeling, reflects daily commitment to seamless supply.

    Supporting Industrial Sustainability and Safety

    Our team faces growing questions about the environmental footprint of specialty alcohols. Sustainability officers ask us for LCA data and energy consumption metrics by batch. We optimize distillation heat recovery, recycle process water, and run solvent recovery loops for ethanol used in cleaning. Cutting unnecessary steps conserves raw materials and energy, while closed-loop transfer lines cut down on fugitive emissions.

    Process safety also grounds our production philosophy. Runaway reactions or process upsets are rare for our team, but emergency drills and shutdowns are regular practice. Layers of safeguards—pressure relief valves, gas detectors, interlocks—reduce the chance of major loss, supporting both personnel safety and asset protection. Quarterly training cycles ensure everyone knows how to handle unexpected events, building competence that stands up through long nights and busy shifts.

    Concerns about chemical exposure at downstream customer sites shape our handling recommendations. Our packing and shipping crew receive thorough training on spill response and the use of PPE. In conversations with clients, we discuss engineering controls—ventilation options, fume hoods, and recommendations for air monitoring during large-scale mixing or tank unloading.

    Continual Improvement and Industry Engagement

    We keep direct lines open to research teams at universities and major chemical companies. Industry input guides many upgrades in both synthesis and handling. Collaborative studies sometimes reveal batch trends, purity effects, or even new potential uses. In one recent project, a customer discovered that controlling the true isomer content in 1,3-Diethoxy-2-Propanol led to improved optical clarity in specialty coatings—this feedback fed directly into process changes for future runs.

    We attend conferences alongside regulatory and supply chain partners, learning how global requirements might affect formulation and packaging. Updates to shipping codes or new worker protection guidelines lead to changes in labeling systems and secondary containment, all designed to provide more transparency and reduce downstream risk.

    Requests for tighter analytical data, such as residual solvent panels or even isomeric ratios, encourage us to upgrade laboratory instrumentation and reporting platforms. As more buyers conduct their own quality checks, traceability and independent verification matter more each year.

    Respecting Raw Material Value and Worker Skill

    No chemical process runs on equipment alone. Experience shapes every production day’s results. Teams respect every truck of ethanol and propylene oxide that rolls through the gate, knowing hours of care at the supplier’s plant are at stake. Storage crews handle connections by hand, listen for leaks, and sample incoming batches—a practice built from past lessons learned the hard way.

    Equipment operators keep detailed logs—pressure readings, temperature trends, even the quality of steam. Each morning’s team brief covers not just maintenance but what went right and wrong with the previous shift. This reflection drives small steady improvements, rather than chasing big fixes after failures occur. By treating plant staff as process owners, not just button-pushers, we catch and correct drift before it ever leaves a product drum.

    Routine cleaning, pump swaps, and scheduled downtime keep the plants running longer between unscheduled stops, reducing pressure for last-minute rework or rush orders that could mean corners cut.

    Technical Support Extends Beyond the Plant Gates

    After drums leave our yard, support team members stay engaged with end-users—calling to walk through first-use protocols, discussing compatibility with plastics and elastomers, or helping interpret chromatograph traces on-site. If a QC lab finds a result out of spec, a process engineer traces back through the batch run record, helping to troubleshoot while minimizing customer downtime.

    Production history backs every claim made. With a decade or more of archived analytics, we can quickly retrieve batch records and impurity profiles if needed. Archival storage of analytical data allows backtracking if trends in final product change. This level of transparency builds trust and long-term relationships.

    Supporting new projects means adapting advice to the user’s context; a pilot plant with a single reactor faces different challenges than a multi-line manufacturer with automated controls. Field experience translates the technical, offering practical advice that saves time, waste, and often money.

    Real-World Troubleshooting and Flexibility

    Production lines never operate in a vacuum. Unplanned events—unexpected pump shutoff, a raw material delivery weather delay, occasional changes in incoming material quality—force adaptivity at every level. The difference between robust chemical manufacturing and routine batch operation lies in how well teams handle these deviations.

    Our staff has worked through supply chain shocks, equipment breakdowns, and seasonal changes that affect process conditions. Maintaining an extra supply of key raw materials buffers against common disruptions, while validated secondary suppliers provide backup for longer interruptions. Routine cross-training allows any crew member to pick up where someone else left off, limiting operational hiccups.

    Collaboration between shift supervisors and maintenance—swapping out seals, checking pH probes, retuning control circuits—keeps process drift contained. Ongoing dialogue with internal R&D means real-time technical support when field feedback reveals a trend, whether in color drift or odor threshold. Flexibility creates resilience, ensuring customers receive consistent product no matter what challenges arise.

    Preparing for The Future

    The specialty chemicals industry changes constantly. New applications, regulatory shifts, and customer expectations keep technical and production teams learning. Future directions may call for reduced-odor or ultra-low residue products. Responsible chemical manufacturing demands sustainable sourcing, more waste reduction, and transparent reporting.

    Our company invests time and resources to anticipate these shifts. Regular upgrades to analytic equipment, digital batch tracking, and automation allow more precise control and documentation. Ongoing training for all staff ensures new team members step into a legacy of discipline, continuity, and pride.

    Understanding what works in real-word applications and what fails in the field helps refine internal standards. Listening and adapting to client feedback—whether it comes in the form of routine complaints or breakthrough successes—keeps our product competitive and dependable, year after year.

    Conclusion: Bringing Real-World Value

    The story of 1,3-Diethoxy-2-Propanol roots in daily effort: careful synthesis, close monitoring, and an open channel with every user. By respecting process discipline, valuing skills learned on the plant floor, and keeping up with the realities that customers face, we continue supplying a product that does its job—every day, in every run. We deliver more than a chemical: we deliver confidence built on experience, discipline, and an eye for what matters most.