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HS Code |
917026 |
| Iupac Name | 1-(3-bromophenyl)propan-2-amine |
| Molecular Formula | C9H12BrN |
| Molecular Weight | 214.10 g/mol |
| Cas Number | 152628-03-0 |
| Appearance | Colorless to pale yellow liquid |
| Smiles | CC(N)C1=CC(=CC=C1)Br |
| Pubchem Cid | 20223368 |
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Not every day do you come across a specialty chemical like 1-(3-Bromophenyl)-1-methylethylamine that quietly shapes progress in the lab and on the production floor. You can call it a workhorse for synthesis. That chunky bromine atom on the third carbon grabs the attention of chemists for a reason, and folks with a bit of experience know that the right molecular tweak changes the tone of a whole reaction. Say you are building new pharmaceutical scaffolds, tinkering with catalysts or just hunting for that elusive intermediate — this compound has a way of turning up on bench tops for a reason.
Simple details matter. This molecule comes as a crystalline solid, often pale in appearance. The formula, C9H12BrN, highlights a balance between a sturdy aromatic ring and a short amine side chain, set off by a methyl group for bulk and a bromine atom for reactivity. What I see in the bottle is a manageable, not-too-hygroscopic powder that stores well. Experienced hands wear gloves and work under ventilated hoods; this brominated amine isn’t finicky but still commands respect.
Purity leaves less room for doubt when you aim for a clean product downstream. Reliable producers offer it at 98% and above, which keeps reactions from drifting with side products sneaking in. Typical batch sizes land in the multi-gram range for R&D settings—a helpful amount for both exploratory synthesis and pilot runs, whether you’re in a university lab or a startup’s cramped quarters. The melting point falls around 68-72 degrees Celsius, so anyone with a hot plate senses where solid turns to liquid.
For me, no chemical exists in a vacuum. Every choice on the shelf signals a purpose. 1-(3-Bromophenyl)-1-methylethylamine draws its fans among those shaping new benzylamines, secondary amines, or complex heterocycles. Its backbone, the 3-bromophenyl group, gives it a foothold in medicinal chemistry. Teams developing drug leads lean on this motif as a handle—modifying, coupling, or substituting to suit bioactive shape requirements. More than once, I’ve seen it sited in research on CNS agents and newer analogs of established therapeutics.
Solid reasoning runs through the process: the bromine opens a gate for further Suzuki, Heck, or Buchwald couplings. Cross-coupling reactions rely on robust starting points, and 1-(3-Bromophenyl)-1-methylethylamine delivers. You get a predictable partner for palladium-catalyzed events; the amine offers a strong nucleophile, which enables downstream acylations, alkylations, or even reductive amination. There’s less fuss about ambiguous by-products because this structure resists wild rearrangements. When scale-up comes around, the molecule remains steady enough for confident work.
Inside labs and across industries, researchers push on boundaries. With 1-(3-Bromophenyl)-1-methylethylamine, I’ve watched teams design radiolabeled analogs for PET imaging work, shrink-wrap the molecule into custom resins, and try templating it into frameworks for sensors. Take the teaching labs—students handle this compound when learning the ropes of aromatic substitutions and practical amine chemistry. Learning what works (and what doesn’t) with such a well-defined molecule speeds up the curve for everyone from the undergraduate to the postdoc.
Sometimes folks ask, “Why not just use an unsubstituted amphetamine or a different bromine isomer?” There’s wisdom in that question. Chemists know that where you put a substituent on a ring changes everything. Swapping the bromo group to the para or ortho positions puts you in a different synthetic universe. The meta arrangement in this molecule picks out routes not always open to other isomers, and changes things like electronic properties, steric hindrance, and the types of cross-coupling reactions that run to completion without headaches.
Those who have swapped one amphetamine derivative for another can tell you that real-world outcomes shift. The 3-bromo plays specifically with electron withdrawal and reactivity at the ring; ortho- or para-bromine groups offer a different set of options and pitfalls. While para- substituted amines show up in some brighter fluorescent dyes, the meta-bromo pattern better suits CNS research tools because it steers clear of unwanted metabolic paths. When purity and predictability decide the fate of a thirty-thousand-dollar project run, the difference between “good enough” and “just right” is the difference between this compound and whatever sits next to it on the rack.
Even the best compound doesn’t do the work itself; the people handling it drive research forward. I saw 1-(3-Bromophenyl)-1-methylethylamine open up fresh approaches when teams explored activity at monoamine transporters. There’s a practical edge to its adoption, too—its consistent behavior in solution, reproducible yields in coupling reactions, and solid shelf life. Reliable chemistry is the bedrock of innovation. A compound that cuts down on purification headaches and lets you track your progress by straightforward chromatography earns its keep.
The educational value rides along, too. In my own teaching days, I relied on straightforward aromatic amines to show what can happen with straightforward substitutions and cross-coupling. When students work hands-on with a molecule like this, good science habits stick. Keeping procedures clear—focusing on one new functional group at a time—turns classroom lessons into useful laboratory skills.
The number of reports that cite 1-(3-Bromophenyl)-1-methylethylamine keeps growing. Reviews in medicinal chemistry journals draw attention to its role in drug discovery screens. Teams looking for dopamine or serotonin analogs pass through the meta-bromo checkpoint while refining SAR (structure-activity relationship) data. I’ve seen researchers leverage it as a block in photonic materials, setting it up for future use in organic electronics or responsive polymers.
Responsibility walks hand in hand with access to specialty chemicals. Anyone who spends enough time with aromatic amines or brominated compounds gets in the habit of treating each bottle with respect. 1-(3-Bromophenyl)-1-methylethylamine isn’t notorious for wild reactivity. Still, skin exposure, inhalation, and accidental contact mean you put the gloves on, you check the ventilation, and you keep a spill kit in arm’s reach. Clear, visible labeling and informed use protect labmates and the larger community.
It makes a difference to get your chemicals from distributors with a reputation for careful sourcing, stable supply chains, and good communication. Inconsistent batches or confusing certificates of analysis slow research and cost teams time they never get back. I’ve built trust with colleagues and suppliers who honor transparency and verify product integrity. Verifiable data, not just a sales pitch, keeps research moving and guards against bitter setbacks.
Not every compound should be easy to buy in barrels or by the kilogram. 1-(3-Bromophenyl)-1-methylethylamine brings a degree of sensitivity in sourcing, because some analogs have histories tangled with psychoactive research and regulation. Labs and suppliers alike share the job of due diligence — not just for compliance, but for ethical stewardship. In my experience, responsible handling practices mean screening customers, keeping clear records, and cooperating with regulators who ultimately safeguard public safety.
Suppliers carry much of the burden for educating end users, but scientists own the choice for how and why they use specialty chemicals. I’ve watched respected colleagues communicate openly about research aims, anticipate questions, and lead by example on safety and transparency. Good science can’t last without trust; trust begins where transparency and education begin, too.
Money and time both matter. Researchers often want the lowest price or a single-vendor solution, but my experience has shown that smart investment pays off at every stage. Higher purity, detailed supporting documentation, and ease of access to technical support change the game. With 1-(3-Bromophenyl)-1-methylethylamine, those who choose quality over rock-bottom pricing avoid mysterious lab mishaps and wasted material. That reputation means you know precisely what’s in your bottle, leading to more reproducible results, less troubleshooting, and fewer reruns.
Research teams occasionally weigh custom synthesis versus in-stock supply. In most of my projects, waiting on a tailored batch turns out slower and more expensive than working from high-purity inventory. The best suppliers keep good records of every batch, verify synthetic routes, and run careful quality assurance step by step. Down the road, that care shows up in published data, patent applications, and collaborations—details that sharpen your work and earn confidence with reviewers and funding agencies.
Many areas of synthesis are hungry for building blocks that combine reliability, versatility, and smart reactivity. With concerns about antibiotic resistance, neurodegenerative disease, and environmental monitoring, labs experiment with new amine-based frameworks. The meta-bromo-phenyl core keeps options open for substitution, while the methyl-ethylamine side chain fits neatly with a variety of reactions that create new biologically relevant compounds.
In drug discovery, speed and precision come at a premium. Anything that cuts down on unexpected impurities or unpredictable reactivity matters in the high-stakes world of lead optimization. I’ve seen project timelines compressed by months simply because everyone could trust a shared intermediate compound—unexpected breakdowns or reactivity waste time, money, and patience. A compound like 1-(3-Bromophenyl)-1-methylethylamine sits at the crossroads of analytical precision and creative chemistry.
As commercial and academic need evolves, I picture this compound lending itself to more precise modifications—think isotope labeling, rare element incorporation, or new regioselective coupling protocols. With green chemistry principles front and center, reducing the waste and unpredictable byproducts associated with older bromination methods becomes more important. Cleaner syntheses, more robust purification, and efficient waste handling all lighten the footprint of specialty research chemicals.
No specialty chemical gets by without a few bumps in the road. Sourcing high-purity 1-(3-Bromophenyl)-1-methylethylamine sometimes lags behind demand during spikes of interest. I’ve known labs forced to pause mid-sprint, waiting for delayed shipments or replacement batches after failed quality checks. Community-driven databases and chemical registries help share up-to-date sourcing information and warn against unreliable suppliers. Experienced researchers pay it forward, flagging issues and helping the field build up a collective wisdom about trustworthy sources.
With growing pressure worldwide to cut down on hazardous substances, regulatory compliance tightens up year after year. Safe handling advice develops faster than in the past, shaped by universities, government agencies, and trade groups swapping lessons learned in the field. Internal lab protocols and new analytical techniques to detect trace contamination put more power in the hands of the researcher. Documenting what works — and what to avoid — lets future teams focus more on discovery, less on damage control.
Looking back, some labs cut corners with quality control, putting research results at risk. Chasing quick fixes or ignoring batch traceability cost teams dearly in wasted effort and lost grants. Building lasting standards means valuing reproducibility over novelty, recognizing that a clear, traceable source of a compound like 1-(3-Bromophenyl)-1-methylethylamine preserves the whole community’s trust in scientific results. I’ve seen that attention to source and verification gives everyone a better foundation going forward.
Today, best practices focus on batch-level transparency, digital recordkeeping, and rapid response to recall or impurity notifications. Communities of practice—online forums, chemical societies, and internal lab communications—all keep the discussion alive and relevant. Whenever I see a student or early-career scientist stick to those habits, I know future discoveries rest on solid ground.
Chemistry pushes forward with restless curiosity. 1-(3-Bromophenyl)-1-methylethylamine acts as a bridge to new families of molecules, filling gaps in current methods and sparking ideas for future technology. I’ve watched coordination chemistry groups use it as a ligand precursor, while material scientists adapt its structure for high-durability coatings or flexible electronic substrates. The simple changes you make to the amine portion shape binding affinity, color, and electrochemical properties—giving each lab the flexibility to chase its next big idea.
Collaborative projects benefit from well-defined intermediates. Universities and start-ups alike thrive on standards they can trust. With research teams spread across continents and time zones, everyone needs to speak the same language—good documentation, tested material, and clear reporting. In my experience, that consistency makes or breaks high-profile projects, especially under tight deadlines and public scrutiny.
New applications for this compound will likely keep appearing. As demands increase for biomedical imaging, targeted therapy, and diagnostic reagents, the combination of a brominated aromatic ring and a reactive small amine opens doors. I’d wager that as techniques for bioorthogonal chemistry progress, researchers will repurpose 1-(3-Bromophenyl)-1-methylethylamine for labeling proteins, mapping neural systems, or creating diagnostic tracers that demand both stability and customization.
Behind every bottle of 1-(3-Bromophenyl)-1-methylethylamine are teams of people—chemists, trainers, safety officers, and logistics coordinators—who strive to deliver reliable, safe, and effective research tools. I believe good communication beats blind reliance on paperwork or reputations. Little details—a properly cleaned flask, a clear label, a conversation about reaction quirks—often decide the outcome of a project long before publication or patenting.
There has never been a more exciting time to build and use custom small molecules. The tools available put precise control at every workstation. My advice for folks new to the field: lean on peer-reviewed data, value knock-on experience from mentors, and keep safety front of mind. Each order and experiment brings new insights, or at least new cautionary tales to pass along.
It’s easy to focus on the molecule’s technical details and miss the broader story. 1-(3-Bromophenyl)-1-methylethylamine stands out not only for its chemical utility but also for what it demands from all involved—consistent care, sharp attention to detail, and a willingness to adapt and learn. In my time, that made the difference between a long string of setbacks and a string of published results that meant something.
Building the future of chemistry means making thoughtful choices at every level. For researchers, that starts with the recognition that compounds like 1-(3-Bromophenyl)-1-methylethylamine form the backbone of more complex discoveries. Whether your work focuses on core synthetic chemistry, agile response to shifting health needs, or leading-edge diagnostic development, the investments made in quality and best practices come full circle. Each successful reaction, reliable scale-up, or safe teaching lab is a testament not only to the chemistry but also to the community of people working with care and intent. The story continues each time someone unseals that bottle and sets out to explore what more can be done.