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1,3-Adamantanediol

    • Product Name 1,3-Adamantanediol
    • Alias 1,3-Dihydroxyadamantane
    • Einecs 251-974-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    218483

    Name 1,3-Adamantanediol
    Cas Number 500-26-7
    Molecular Formula C10H16O2
    Molecular Weight 168.23 g/mol
    Appearance White crystalline solid
    Melting Point 259-262 °C
    Solubility In Water Slightly soluble
    Density 1.24 g/cm3
    Synonyms Adamantan-1,3-diol
    Structure Type Polycyclic (adamantane core)
    Smiles OC1CC2CC3CC1CC(O)(C2)C3
    Hs Code 29061900

    As an accredited 1,3-Adamantanediol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,3-Adamantanediol is packaged in a 100g amber glass bottle with tamper-evident cap and detailed labeling for laboratory use.
    Shipping 1,3-Adamantanediol is shipped in tightly sealed containers to prevent moisture entry and contamination. The packaging typically complies with regulatory and safety guidelines for organic chemicals. It should be stored and transported in a cool, dry location, away from oxidizing agents, with appropriate hazard labeling, ensuring safe handling throughout the shipping process.
    Storage 1,3-Adamantanediol should be stored in a cool, dry, well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizing agents. Keep the container tightly closed and protected from moisture. Store in a tightly sealed container, clearly labeled. Avoid exposure to extreme temperatures and direct sunlight to maintain chemical stability and prevent degradation.
    Application of 1,3-Adamantanediol

    Applications of 1,3-Adamantanediol in Industrial Manufacturing

    1,3-Adamantanediol is a specialty raw material widely utilized in high-value chemical manufacturing. Our direct supply supports advanced applications in pharmaceutical intermediates, specialty polymer synthesis, high-performance coatings, liquid crystal materials, and organic electronics, offering precise technical parameters and stable industrial integration.

    1. Pharmaceutical Intermediate Synthesis

    Process engineers utilize 1,3-Adamantanediol in the production of antiviral and neurological active pharmaceutical ingredients. Its rigid cage structure allows controlled derivatization, facilitating synthesis of adamantane-based APIs. Manufacturers adopt the diol at key stages to introduce hydroxyl groups, assisting formation of complex heterocyclic compounds essential for CNS drugs. Scale-up adheres to strict GMP, with precise handling under validated conditions to maintain trace impurity profiles.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practices for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (EP) monograph 10.0
    • U.S. Food and Drug Administration (FDA) 21 CFR Part 211
    • China GMP Annex 1 (2010 Edition)

    Typical usage ratio

    • 0.5–5 mol% as starting material in API intermediate synthesis, adjusted by final compound route and stoichiometry of the derivative step

    Downstream process integration

    • Batch introduction during alkylation or acylation reactions
    • Intermediate isolation via crystallization
    • Hydroxyl activation with coupling reagents
    • Final step product purification for GMP-grade intermediates

    Final product types

    • Memantine hydrochloride
    • Amantadine sulfate
    • Adamantane-derived anti-influenza agents
    • CNS disorder drug actives

    2. Specialty Polycarbonate and Polyester Resin Manufacturing

    Materials scientists value the unique three-dimensional framework of 1,3-Adamantanediol as a diol monomer in engineering plastics. It enhances polymer glass transition, heat distortion resistance, and dimensional stability. Downstream resin manufacturers introduce this diol in step-growth polymerizations, either as a co-monomer or chain modifier, producing high-strength, transparent pellets or films. Strict QC monitoring ensures precise monomer ratios and molecular weight control.

    Industry compliance standards

    • ISO 9001:2015 Quality Management System for chemical production
    • RoHS Directive (2011/65/EU) for electronic and automotive polymers
    • REACH (EC 1907/2006) compliance
    • UL 94 flame class for plastic resin applications

    Typical usage ratio

    • 3–10 mol% as co-diol in polycarbonate and polyester blends; formulation optimized for target mechanical and optical characteristics

    Downstream process integration

    • Esterification reaction at 180–230 °C with alkyl diacid or carbonate
    • Addition to polycondensation split feeds
    • Vacuum devolatilization for low residual monomer levels
    • Pelletizing and extrusion for finished resin or film

    Final product types

    • High clarity polycarbonate sheets
    • Adhesive resins for optical media
    • Molding granules for automotive or consumer electronics
    • Engineering-grade polyester films

    3. High-Performance UV-Curable Coatings

    Formulators in the coatings industry incorporate 1,3-Adamantanediol as a reactive coreactant to raise crosslinking density and surface hardness in UV-curable oligomers. The rigid diol structure imparts scratch resistance to cured films, especially for premium flooring and display coatings. Its controlled substitution yields reproducible reactivity in acrylate and urethane-based clearcoats. Regulatory checks target migration and photoinitiator compatibility for industrial compliance.

    Industry compliance standards

    • EN 71-3:2019 Migration of certain elements (decorative surfaces)
    • ISO 12944 (Corrosion protection of steel structures by protective paint systems)
    • EHS Management System for safe photoinitiator and monomer handling
    • OEM customer proprietary formulation specifications

    Typical usage ratio

    • 2–8 wt% of total oligomer solids in UV-acrylate and polyurethane clearcoat formulations; adjusted per targeted hardness and mutagenicity requirements

    Downstream process integration

    • Premix with base resin and diluent
    • Chain extension or functionalization with (meth)acrylate groups
    • Inline monitoring of viscosity and reactivity
    • Final dispersion prior to radiation curing application

    Final product types

    • Industrial flooring topcoats
    • Scratch-resistant smartphone screen coatings
    • UV-cured optical fiber coatings
    • High-gloss wood and plastic finishes

    4. Liquid Crystal and Organic Display Material Production

    R&D and production teams employ 1,3-Adamantanediol in synthesizing molecular building blocks for liquid crystal orientation layers and organic electronic matrices. The adamantane scaffold improves molecular order and thermal properties, aiding in both alignment layer UV-hardening and LC host formulation. Material introduction hinges on purity; precise fractionation and solvent choice during production prevent artifact formation in display-quality intermediates.

    Industry compliance standards

    • IEC 61249-2-41:2014 for halogen-free base materials in displays
    • JEITA-ED-7303 Quality Assessment for electronic materials
    • RoHS/REACH for hazardous substance management
    • Customer internal reliability/burning test standards for display modules

    Typical usage ratio

    • 1–6 mol% as component of LC orientation or mixture, tailored by required birefringence and curing kinetics

    Downstream process integration

    • Addition during alignment layer or host synthesis
    • Co-polymerization with (meth)acrylate or imide monomers
    • Fractional distillation for electronic-grade purity
    • Mixing under nitrogen to prevent discoloration

    Final product types

    • LCD/LCM alignment coatings
    • High-Tg organic semiconductors for OLED displays
    • Anti-reflective and planarization films for thin-film displays
    • Printed circuit insulating films

    5. Advanced Functional Additives in Lubricant and Oil Formulations

    Chemical lubricants manufacturers add 1,3-Adamantanediol derivatives as specialty antiwear or friction modifiers in synthetic and semi-synthetic oil blends for high-temperature applications. The unique molecular configuration improves oxidative stability and load capacity. Linear dosing and compatibility testing with common base stocks ensures sustained performance. Materials traceability from initial batch lot to finished blend supports quality systems crucial for automotive and machinery lubrication markets.

    Industry compliance standards

    • ISO 21469 Hygiene requirements for product formulation
    • SAE J300 Viscosity grading system (finished lubricants)
    • API Service Category (motor oils)
    • OEM transmission and gear oil approval lists

    Typical usage ratio

    • 0.2–1.5 wt% based on total lubricant formulation; fine-tuned after tribology bench testing

    Downstream process integration

    • Blending with synthetic esters, PAOs, or mineral base stocks
    • Shear stability and oxidation resistance trials
    • Filtration and defoaming quality checks
    • Batch tanks with in-line additive dosing

    Final product types

    • Powertrain synthetic lubricants
    • High-temperature gear oils
    • Compressor and hydraulic fluids
    • OEM-approved extended life greases

    6. Crosslinking Agent in Specialty Adhesive Formulations

    Adhesive manufacturers use 1,3-Adamantanediol to boost rigidity, heat stability, and bond strength in specialty reactive adhesives, including high-performance structural products. Its secondary alcohol groups react with isocyanates or polyacids to form three-dimensional networks. Controlled substance monitoring and in-process rheology adjustments remain key for batch quality, especially in industrial and electronics bonding systems.

    Industry compliance standards

    • ISO 4587 Adhesives—Shear strength test protocols
    • EN 923:2015 Terminology for adhesives
    • REACH SVHC assessment for safe use in assembly lines
    • ASTM D1002 Metal-to-metal adhesive bond test

    Typical usage ratio

    • 1–7 wt% within adhesive formulation, balanced with crosslinker reactivity for mechanical performance

    Downstream process integration

    • Incorporation in mixing vessel after base resin
    • Isocyanate or polyacid addition under controlled temperature
    • Viscosity monitoring, pH checks, and adjustment
    • Packaging in moisture-sealed cartridges or syringes

    Final product types

    • Electronics assembly adhesives
    • Structural metal bonding systems
    • Specialty heat-cure glues for high-temp applications
    • Foil laminate adhesives
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    Certification & Compliance
    More Introduction

    1,3-Adamantanediol: Solid Foundation for Advanced Chemistry

    What Sets 1,3-Adamantanediol Apart

    Manufacturing 1,3-Adamantanediol, also known as 1,3-dihydroxyadamantane, gives insight into a molecule with a sturdy, diamond-like core and strong chemical stability. The product’s structure comes from adamantane, a tricyclic saturated hydrocarbon, imparting rigidity and a unique three-dimensional framework. This molecular backbone allows 1,3-Adamantanediol to resist deformation under heat and stress, making it a reliable candidate in high-performance materials. In the daily work of synthesis, this translates to less degradation and fewer side reactions when compared to linear diols or simpler cyclic alcohols. The two hydroxyl groups at positions 1 and 3 facilitate controlled reactivity, essential for targeted functionalization.

    Chemists and material scientists value predictability in building block behavior. After years of working with alcohols and diols, the results from adamantane derivatives consistently stand out. Unlike flexible aliphatic diols, which often show changes in conformational shape under processing conditions, 1,3-Adamantanediol maintains a rigid stance. This gives products enhanced mechanical strength and thermal endurance. For those working in fields like polymer synthesis, coatings, and pharmaceuticals, such reliability helps cut down troubleshooting and wasted batches.

    Handling this compound in the plant reflects its robust nature. Whether charging reactors for polymer precursor production or purifying the diol for specialty intermediates, the process runs smoother. Typical product specification fields—such as melting point, purity, and particle size—are tightly controlled in our facility. In most applications, we supply 1,3-Adamantanediol in a white crystalline or powder form, with purity levels greater than 99 percent, and a melting range that supports both solid-phase and melt processing methods. These details shape daily decision-making on dosing, mixing, and downstream application.

    Technical Value in Real Industry Uses

    One thing about making and using 1,3-Adamantanediol is that you rarely see “off-the-shelf” solutions. Each customer approaches with unique goals. Formulators within the resin and plastics fields often look beyond ordinary glycols because adamantane’s rigid core boosts dimensional stability in cured products. That difference shows up in the finished articles: higher glass transition temperatures, improved scratch resistance, and longer lifespan for demanding applications. Some of the end uses include optically clear polycarbonate lenses, specialty engineering plastics, and high-end adhesives—markets where a batch recall can cause more than inconvenience.

    Pharmaceutical research teams inquire about 1,3-Adamantanediol for its pharmacophore potential. The adamantane motif, already found in antiviral drugs like amantadine, gives directionality and control over biological activity. The added diol groups serve as anchoring points for further functionalization. Over the years, our partners in drug development and diagnostics found that using this compound as a scaffold helps them design candidates with improved metabolic stability, offering a practical route to balance reactivity and safety. In the lab, its solid state and precise melting properties simplify weighing and dispensing, ensuring every formulation sits within target parameters.

    Another growing area for 1,3-Adamantanediol sits in catalysis and advanced materials. Research teams are exploring how its rigid cage-like structure anchors ligands and functional groups in place, opening new paths in organometallic catalysis, sensing, and performance additives for electronics. It excites process chemists to work with a substance that doesn’t lose shape or effectiveness when conditions change, giving confidence that products will perform as designed, even after scale-up.

    Comparisons with Other Adamantane Diols and Common Diols

    Within our own catalog, we see steady demand for adamantane derivatives with varying placement of hydroxyl groups. Comparing 1,3-Adamantanediol to its siblings, notably 1,2- and 1,3,5-derivatives, subtle shifts in substitution have real consequences in the lab and plant. The spacing of hydroxyl function in 1,3-Adamantanediol enables more effective crosslinking or bridging in polymer matrices, distinct from the more closely placed 1,2-diol variant. For resin formulators chasing specific network densities or branching characteristics, this selection means predictable handling of mechanical and thermal profiles.

    Contrasting adamantane-based diols with common aliphatic diols such as 1,4-butanediol or 1,2-ethanediol—familiar names to most chemical workers—the differences become clear. Aliphatic diols behave as flexible spacers, which suits them in plasticizers and antifreeze blends. In contrast, the impact of the rigid adamantane core shows up in firmer coatings, higher load-bearing composites, and improved resistance to chemical breakdown. During customer trials, polymers incorporating 1,3-Adamantanediol demonstrate less yellowing and shape distortion under stress. This feedback doesn’t come from theory or advertising claims; it’s what line operators and quality inspectors report after months on the production floor.

    Why 1,3-Adamantanediol Matters in Practice

    Making chemicals for specialty uses always brings the challenge: how do raw materials behave under real-world stress? 1,3-Adamantanediol steps up under repeated cycles of heating and cooling, UV exposure, and contact with solvents. In the field, coatings using our diol survive outdoor environments with less chipping and fading compared to competitors using more common diols. The chemical structure holds up not just in a lab notebook but in hands-on situations—outdoor architectural panels, medical device housings, and optical equipment enduring daily use.

    From an operations standpoint, the low volatility and manageable dusting characteristics help technicians work safely and efficiently. Unlike volatile solvents or dust-prone fillers, our finished product stores well in simple high-density polyethylene containers. This means less wastage due to clumping or off-gassing, smoother logistics, and easier scale up—points that affect not just cost but regulatory compliance and workplace safety.

    On the sustainability front, the efficient carboxylation and reduction methods we apply during synthesis minimize byproducts. Our team works to recycle solvents and adopt closed-process systems to cut emissions. Over the past five years, process yield improvements and waste recovery steps have reduced our site’s environmental load. While large-scale adoption of circular economy practices remains a challenge, choosing robust molecules like 1,3-Adamantanediol forms part of a broader strategy. This aligns with growing demand for lower-carbon materials and supports both internal sustainability goals and those of downstream users.

    Handling and Storage Insights from Daily Operations

    After shipping and storing thousands of kilograms, some lessons become clear. 1,3-Adamantanediol’s stable nature means it resists hydrolysis and oxidation in typical indoor storage conditions. Long shelf life and low susceptibility to airborne moisture simplify warehouse protocols. Mills, mixers, and feeders see less buildup or clogging because of the uniform crystalline form. Site teams get a product that feeds smoothly, whether bagged, drummed, or loaded into hoppers. Feedback from our own maintenance staff tells a story: less cleaning time, fewer unplanned stoppages, and more predictable batch results.

    From a quality control perspective, process upgrades let us track each lot through in-line spectroscopic monitoring and batch-level purity verification. Customers have noted fewer complaints or returned shipments since these systems rolled out. Accurate melting point and impurity profiles let end users fine-tune processes, whether blending with other monomers, introducing catalysts for selective conversion, or controlling particle size at the micron level for compounding.

    Taking Chemistry Further with Trustworthy Building Blocks

    The most successful recipes, whether for structured polymers or fine chemicals, build from consistent starting points. Our experience as a direct manufacturer keeps focus on the details: tight control of process conditions, reliable supply chains, and hands-on quality checks. The 1,3-Adamantanediol leaving our plant carries a pedigree—tracked back through raw material sourcing, process parameters, and batch history. The growing customer base draws confidence not only from product specs but also from real-world performance: stable output, manageable logistics, safe handling, and evidence of improved end-use properties.

    Through direct feedback loops—from technical support teams, field engineers, and commercial installers—product improvements never stop. New demands from green materials, medical devices, and electronics drive adjustments to synthesis, handling, and packaging. Cross-functional teams, from R&D to logistics, track trends and performance at each step. Results flow back to line supervisors and process operators, anchoring improvements not in theory but in grounded process changes.

    Shaping Solutions for Tomorrow’s Chemistry

    The role of 1,3-Adamantanediol as a specialty building block continues to evolve. Demand grows for advanced performance coatings, data storage materials, and components integral to smart devices and vehicle interiors. Each new partnership tests the limits of what our molecule can achieve. Product modifications, such as functional group extensions or tailored particle sizes, come out of lab trials and head directly to pilot scale in collaboration with trusted partners. These aren’t generic tweaks to target mass appeal—they come from persistent troubleshooting and custom formulation driven by end-user realities.

    For new entrants and seasoned product developers alike, knowing the differences between standard diols and adamantane-based options like 1,3-Adamantanediol marks the start of more advanced chemistry. Cross-disciplinary teams in our network often exchange insights about solubility, reactivity, and compatibility in niche applications. These exchanges, alongside careful record-keeping of process outcomes, guide incremental improvements in yield, process robustness, and long-term reliability. Tapping decades of experience in adamantane chemistry helps sidestep many pitfalls that come with trying untested alternatives or inconsistent supply.

    Commitment to Supporting Innovation

    Working directly as both producer and partner, we keep innovation at the front without neglecting practicality. 1,3-Adamantanediol exemplifies what can be achieved with robust chemical engineering, steady supply lines, and collaborative technical support. Rigorous tracking from raw input to finished product, continuous process optimization, and close monitoring of regulatory shifts all play a role in delivering a product that does more than meet specifications—it stays relevant as industries and needs shift.

    Ongoing investments in process safety technology, in-line purity analysis, and resource recovery reflect lessons learned over years of batch and continuous manufacturing. Our facilities meet modern safety and environmental standards—not only to comply with regulations but to ensure the well-being of the teams who make, ship, and support these advanced building blocks. Teams stay up to date through regular training and active participation in technical review cycles, so product consistency aligns with industry requirements and future-facing applications.

    Insight from Real-World Users

    Direct feedback from downstream applications often guides future process change more clearly than any analytical report or marketing goal. Conversations with end users—from resin casting shops to pharmaceutical research labs—frequently reveal how subtle changes in particle size distribution or melting profile affect processing. Adapting output to customer-specific workflows reduces rework on both sides. When a lens manufacturer discovered unexpected haze in a pilot run, close collaboration revealed that a minor tweak in crystallization step during production resolved the issue, leading to a sharper, more consistent final product.

    Case studies accumulate with each passing year. Producers of medical device components noticed a reduction in surface flaws and improved batch consistency after changing over from conventional diol alternatives. Polymer researchers pushing the envelope for lightweight composites found reproducible gains in impact strength and clarity when using our adamantane diol. These aren’t empty testimonials, but real accounts gathered and acted on in direct dialogue with users setting industry benchmarks and validating manufacturing choices.

    Meeting Tomorrow’s Standards

    The story of 1,3-Adamantanediol at our facility keeps growing, driven by a belief that quality building blocks form the basis of trusted solutions. The reliability, safety, and performance delivered today set expectations for tomorrow’s innovations. As industries seek greener profiles and improved outcomes, our work in refining process choices, monitoring product through each shipment, and listening to those on the front lines carries on.

    From synthesis to shipment, 1,3-Adamantanediol remains a mainstay for anyone advancing specialty chemistry. Its rugged structure, controlled reactivity, and consistency in plant and field applications distinguish it from both generic and specialty diols. Reliable sourcing and support, drawn from lived experience, ensure this product forms part of the next generation of resilient, high-value materials.