|
HS Code |
606030 |
| Chemical Name | 1,2-Phenylenedioxydiacetic Acid |
| Molecular Formula | C10H10O6 |
| Molecular Weight | 226.18 g/mol |
| Cas Number | 6342-15-4 |
| Appearance | White to off-white solid |
| Melting Point | 170-173 °C |
| Solubility In Water | Slightly soluble |
| Boiling Point | Decomposes before boiling |
| Synonyms | o-Phenyleneglycol-bis(acetic acid), 1,2-Bis(carboxymethoxy)benzene |
| Smiles | O=C(O)COc1ccccc1OCC(=O)O |
As an accredited 1,2-Phenylenedioxydiacetic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White powder sealed in a 100g amber glass bottle with tamper-evident cap; labeled with chemical name, formula, and safety information. |
| Shipping | 1,2-Phenylenedioxydiacetic Acid should be shipped in tightly sealed containers, protected from moisture and direct sunlight. It must be packaged in compliance with relevant safety regulations for chemicals, using cushioning materials to prevent breakage during transit. Proper labeling, including hazard identification, is essential to ensure safe and efficient handling and delivery. |
| Storage | **1,2-Phenylenedioxydiacetic Acid** should be stored in a tightly closed container, in a cool, dry, well-ventilated area, away from incompatible substances such as strong oxidizers. Protect the chemical from moisture and direct sunlight. Ensure the storage area is clearly labeled and access is restricted to trained personnel. Use secondary containment to prevent spills and environmental contamination. |
Applications of 1,2-Phenylenedioxydiacetic Acid in Industrial ManufacturingAs a direct manufacturer, we supply 1,2-Phenylenedioxydiacetic Acid for select industrial applications where its unique molecular structure contributes to targeted performance improvements and regulatory compliance. Below we outline key sectors where our product integrates into downstream production, providing technical formulation details from a producer’s perspective. 1. Specialty Polymer Modifiers for Engineering PlasticsFormulators in the engineering plastics sector use this diacid as a precision comonomer to enhance thermal stability, hydrolysis resistance, and mechanical strength in polyesters, polyamides, and related co-polymers. Its use is concentrated in high-performance injection-molded components for critical applications, where compliance with automotive or electronics sector standards is required. The diacid enters polymerization reactions as a direct chain-building unit, offering aromatic rigidity while introducing flexible ether bridges to the backbone, beneficial for demanding use-cases. Industry compliance standards
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2. Monomer for UV-Curable Oligomers in Industrial CoatingsResin developers utilize this diacid as a specialty building block for UV-curable oligomer synthesis, enhancing adhesion, flexibility, and weatherability in industrial coating systems. The compound introduces aromatic ether linkages favorable for crosslinking density control, color stability, and resistance to degradation under repeated UV exposure. Its adoption remains specific to high-performance coatings intended for metal, plastic, and composite substrates in sectors such as electronics and automotive refinishing. Industry compliance standards
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3. Intermediate for Pharmaceutical Impurity Profiling Reference StandardsChemical analysis and quality control laboratories at pharmaceutical manufacturers rely on certified reference materials synthesized from this diacid to support impurity profiling, stress testing, and stability-indicating method validation for complex APIs. Its defined molecular structure aligns with USP/EP monograph requirements for impurity control, particularly in regulated markets needing traceable analytical standards. The compound is incorporated during impurity marker synthesis and is not present in finished drugs but is vital for compliant analytical characterization and regulatory submissions. Industry compliance standards
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4. Precursor in Photographic Chemical Reagent SynthesisIn specialty photographic chemical manufacturing, our diacid is processed into stabilizer agents and fog-inhibiting additives for high-sensitivity film and paper emulsions. Its aromatic and ether functionalities influence developing agent selectivity and shelf-life, supporting controlled reduction reactions and image clarity in professional laboratory-scale processes. This application is governed by strict quality and compositional tolerances demanded by photographic materials consortia and international chemical inventory regulations. Industry compliance standards
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Our line of 1,2-Phenylenedioxydiacetic Acid has grown from years of practical hands-on chemistry, daily trials in the reactor hall, and a close working relationship with both upstream raw material suppliers and downstream end-users. At the plant, we treat this specialty compound as more than just a formula, because it often forms the starting point or critical intermediate for chemical syntheses that demand reliability—not just in purity, but in consistency. Every year, we adjust and optimize both synthesis routes and purification steps to keep up with shifting technical requirements, regulatory expectations, and the growing demand for higher precision in specialty chemicals. End users in the pharmaceutical, dye, and polymer industries have raised the bar for trace impurity levels, color characteristics, and batch-to-batch reproducibility, and we meet those with constant analytical verification, not just routine paperwork.
Our most popular product model for 1,2-Phenylenedioxydiacetic Acid (also known as ortho-phenylenedioxydiacetic acid) offers purity levels regularly exceeding 99%. Our team measures this using a combination of HPLC and melting point determination, and we have seen over the years how small shifts in these metrics translate directly into downstream performance. A slight deviation in purity often spells headaches in multi-step syntheses or final product color, and our lab technicians have resolved more than a few crises over the years by tracking these details from raw input to finished acid. Instead of shipping a commodity-grade acid, we keep our batches free from chlorinated byproducts, residual solvents, and oxidation products, since our experience has shown their presence can trigger off-odors, haziness, or loss of catalytic activity in subsequent reactions. We regularly hear from long-term customers who build their syntheses around the critical reliability of our supply, thanks to our full traceability and transparent quality data on each dispatch.
Physical characteristics matter, too. We bulk package our 1,2-Phenylenedioxydiacetic Acid as a white to off-white crystalline powder. The crystal size, moisture content, and tendency toward caking have all received attention from our production crew, because they make a difference in automated dosing, weighing, and transfer. Many customers in synthesis or blending lines prefer a freely flowing powder, so we have tweaked our drying and handling systems to minimize agglomeration without chemical additives. We notice these small steps reduce production downtime in our customers’ facilities, and it’s the sort of improvement only direct experience brings.
Visitors to our facility often ask what’s unique about producing this diacetic acid. The answer lies not in the basic reaction but in the conditions we create to control it. Most large-scale syntheses involve condensation or oxidative coupling carried out under carefully calibrated pH and temperature windows. Our team watches for trace metal-ion contamination, chelates interfering agents, and manages solvents to minimize side reactions. Over the years, we have modified catalyst loadings, agitation profiles, and feed order, because small changes in these areas either dampen the yield or heap on unwelcome impurities. In one instance, shifting the order of reagent addition shaved off an entire filtration stage, which dropped processing time and also abruptly improved the color quality of the output crystals.
Purification starts with careful separation of the target material from side products. Our technicians run column chromatography and crystallization trials regularly, staying on the lookout for process improvements that help remove minute residuals without damaging the acid’s chemical integrity. Many improvements have been driven by practical necessity—sometimes as a direct response to customer reports of sticking during tablet pressing or false positives in analytical screening. Our knowledge base doesn’t just come from the textbooks, but from solving these daily challenges on the shop floor, in real time.
This acid functions as a versatile intermediate. Customers from fine chemicals to functional materials sectors seek it out when they want reliability in multi-step reactions. Over the past ten years, we have supplied it for pharmaceutical synthesis and noticed that its performance as a key intermediate rests entirely on the absence of certain trace contaminants. Even a few parts per million of certain impurities can derail an entire clinical lot. Our chemists learned this the hard way during a scale-up for a contract pharma customer, prompting a wholesale review of plant hygiene protocols and enhanced vapor monitoring around all open transfers.
Dye and pigment manufacturers use our 1,2-Phenylenedioxydiacetic Acid to introduce unique chromophores or as a chelation aid. We found through direct collaboration that trace iron impurities, if not managed during synthesis, taint color points and shade reproducibility. Polymer and resin producers look at not just the acid’s purity but its thermal behavior. For them, the accurate melting point and absence of extraneous particulates allow smooth downstream mixing, preventing gel formation or site fouling during extrusion. Through each of these use cases, we’ve built up a logbook of customer-specific adaptations, refined product grades, and trouble-shooting solutions when problems surfaced during pre-commercial trials.
Real distinctions reveal themselves during tough production runs and critical applications—far beyond what appears in side-by-side catalog comparisons. For example, compared to meta- or para-phenylenedioxydiacetic acid isomers, the ortho (1,2-) configuration introduces both reactivity advantages and process challenges. We have seen customers mistakenly substitute one isomer for another to their own frustration, discovering too late that our product’s ortho orientation unlocks faster condensation in certain couplings, but also makes the material slightly more prone to oxidative yellowing if mishandled. Unlike the 1,4- isomer, 1,2-Phenylenedioxydiacetic Acid supplies unique bidentate binding sites for complexation chemistry, which a few of our materials science partners have leveraged for next-generation adhesives and coatings. Our technical support team, with years in production and troubleshooting, stands ready to help clients who need deeper application support beyond just a box delivered to their loading dock.
We manufacture several grades in response to user demand for trace impurity handling. Dyes and pigments users often ask for ultra-low sodium content. To fulfill this, we reconstructed a whole segment of the purification steps, adding cost and complexity, but those efforts paid off for users running into chronic color drift or unwanted haze. Pharmaceutical users push for the tightest limits on halide occurrence, driving investments in ionic analysis and continuous monitoring. Each market segment pushes us to refine specific attributes, and our sales team brings these requests directly to the plant floor. Feedback loops between engineers, plant chemists, and our analytical lab ensure every tweak makes it into the consistent supply chain.
Those who shape chemistry at the molecular level notice the upstream producer’s fingerprint on their results. Our team takes pride in the fact that we do not hide behind traders or brokerage channels; we participate directly in both technical problem-solving and regulatory dialogues, from initial order to technical user support. Because we stay close to our supply chain, raw material surprises or logistics snarls often get resolved with direct communication, not bounced emails. Even changes in regulatory limits or expected impurity portfolios spark quick technical responses, instead of long waits for bureaucratic signoff.
Customers invite us into their troubleshooting sessions because we know the materials not just as a datasheet specification but as the tangible output of human-run reactors, filtration lines, and real-world logistics. A genuine commitment exists here to both technical rigor and responsiveness—major differences that stem from being the direct manufacturer, not another layer in the supply hierarchy.
Many of the most pervasive challenges in producing a reliable specialty acid stem from both global supply risk and fluctuating quality expectations. Sourcing pure precursors such as catechol or glyoxylic acid, which underpin the phenylenedioxydiacetic acid structure, has proved volatile, especially under tightening environmental restrictions abroad. We’ve hedged some of these challenges by qualifying alternative vendors, bringing precursor synthesis in-house, and keeping a steady eye on geopolitical trends that swing price and availability. Our procurement and R&D groups talk weekly, not quarterly, so that raw material crunches never undermine long-term supply contracts.
Regulatory scrutiny forms another constant feature in our daily operations. Not all specialty chemical makers are set up to provide full batch traceability, linked impurity profiling, or rapid compliance documentation for both domestic and export shipments. We have learned to anticipate audits, and often walk regulatory inspectors through both electronic records and physical sampling trails, showing backing data for every claimed specification. Decades of product stewardship form the backbone of our operation; reclaiming solvents, reducing waste streams, and keeping energy-intensive steps within optimal bounds are all things our process engineers prize as achievements, but they also directly translate to stable supply and environmental compliance for every customer, large or small.
Direct manufacturer involvement makes a clear difference in how users experience technical support. We field calls about caking, flowability, minor shifts in color, or unexpected micro-impurities that escaped standard screening. Instead of posting one-size-fits-all recommendations, our plant and R&D staff pool practical insights. An adhesive manufacturer reporting unexpected haze in the finished resin prompted a round of analytical cross-testing on archived sample batches, followed by a route change using alternative chelate agents in the second purification stage. Dye customers encountering subtle color drift at scale benefitted from us embedding extra moisture testing at dispatch, after a spike in local atmospheric humidity during summer storage.
We see real value in fact-based, outcome-driven support, rather than abstract expertise. Working side by side with client chemists, our team has adapted packaging formats, altered particle size distributions, and documented cleaning protocols that helped meet new regulatory standards across regions. This two-way learning doesn’t just protect our reputation—it enables our clients to launch new products with fewer surprises.
Technical demands never stay still. Our customers pursue ever narrower impurity tolerances, higher purities, and stricter regulatory registrations. Meeting these calls for a practical, flexible approach. We set up expanded pilot reactors to trial new process tweaks and validate downstream usability before any change hits commercial scale. No matter how trivial a formulation looks on paper, every single adjustment meets real-world test runs, with attention paid to filterability, particle size control, and how the material behaves under actual blending conditions.
When faced with application failures or scaling headaches, we dispatch technical liaisons to talk directly with engineering or QA staff at client sites. Batch-by-batch quality logs, not just summary COAs, allow us and our clients to trace root causes rather than swap blame. Regulatory changes (such as new REACH substance list modifications or local export bans) trigger joint action plans early, with our team preparing alternate compliance dossiers or new grades in anticipation—not simply reacting to fines or rejections at the border.
Sustainability pressure has transformed how many chemical producers operate, including our own. We respond to end-user and regulatory demands for lifecycle transparency, greener routes, and lower-carbon processing not because it makes for good headlines, but because it shields both client and company from future volatility. Process heat and water recirculation improvements, solvent recovery systems, and redesign of multi-purpose reactors all emerged from frank dialogue between plant operations and supply chain managers, rather than short-term cost cutting.
We actively pursue reduction of hazardous byproduct formation. In pilot and commercial settings, we’ve implemented dual containment and in-line monitored vent handling to keep fugitive losses in check. Product stewardship means providing disposal guidelines consistent with best global practices, especially for users in tightly regulated end-markets. Clear documentation and transparent reporting, rooted in real operations data, give our partners assurance that every shipment reflects stringent standards from ground up.
Being the manufacturer, not a trader, gives us unique advantages. Honest, up-front dialogue with field chemists, purchasing managers, and compliance officers lets us anticipate issues before they escalate. Whether it’s reformulating for allergen-free status, minimizing heavy metal content below evolving patch test thresholds, or adjusting particle size for new tablet presses, we rely on direct communication, plant experience, and strict product tracking to keep our partners’ processes running.
We work with users who don’t just need a commodity intermediate—they need a versatile, clean aromatic acid that survives real-world handling, storage, and process variables. Each year, we invest in both people and technology to stay at the forefront of what customers expect in quality control, reliability, and direct technical access. Customers who visit our plant see the difference in both process discipline and practical responsiveness. Every shipment of our 1,2-Phenylenedioxydiacetic Acid reflects years of learning, adaptation, and a deep respect for how chemistry and manufacturing shape the future together.