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HS Code |
927295 |
| Cas Number | 567-11-3 |
| Molecular Formula | C12H26O2 |
| Molecular Weight | 202.34 g/mol |
| Appearance | White solid |
| Melting Point | 63-66 °C |
| Boiling Point | 228-230 °C at 15 mmHg |
| Density | 0.893 g/cm³ at 25 °C |
| Solubility In Water | Insoluble |
| Refractive Index | 1.452 |
| Flash Point | 164.6 °C |
| Synonyms | 1,2-Dodecanediol; Lauro-1,2-diol |
| Pubchem Cid | 98315 |
As an accredited 1,2-Dodecanediol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1,2-Dodecanediol is packaged in a 500g amber glass bottle with a secure screw cap, featuring clear labeling and hazard symbols. |
| Shipping | 1,2-Dodecanediol should be shipped in tightly sealed containers, protected from moisture and direct sunlight. It is typically transported as a non-hazardous substance under normal conditions, but care should be taken to avoid extreme temperatures. Proper labeling and documentation are required to comply with shipping regulations and ensure safe delivery. |
| Storage | 1,2-Dodecanediol should be stored in a tightly closed container, kept in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizing agents. Protect from moisture and direct sunlight. Ensure proper labeling and safety measures to prevent accidental spills or contact. Follow all recommended safety guidelines for chemical storage. |
Applications of 1,2-Dodecanediol in Industrial ManufacturingAs a direct manufacturer with long-standing experience in the synthesis and supply of 1,2-Dodecanediol, we support world-leading producers in multiple industrial sectors. Below, we outline specific, real-world application scenarios, covering industry-driven integration practices, compliance benchmarks, formulation parameters, processing steps, and end-use product types based on established use cases of this specialty diol compound. 1. Cosmetic Emulsifier and Cream Base Manufacturing1,2-Dodecanediol serves as a multifunctional agent within personal care industrial formulas, particularly for skin cream bases and emulsions. It acts both as a mild emollient and a supporting antimicrobial substance, replacing harsh preservatives without compromising shelf life. Regulatory-driven manufacturers rely on this diol to enhance spreadability and product stability, working within microbiological preservation constraints and texture optimization targets. R&D and QC departments adjust the dosage according to ingredient interaction profiles, skin tolerance studies, and regulatory concentration limits relevant to finished product claims. Industry compliance standards
Typical usage ratio
Downstream process integration
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2. Industrial Lubricant Ester SynthesisIndustrial production of high-performance synthetic esters for metalworking fluids, refrigeration oils, and environmentally benign hydraulic lubricants incorporates 1,2-Dodecanediol as a diol feedstock. The controlled reaction with various fatty acids produces diester and monoester lubricants prized for high thermal stability, hydrolytic resilience, and reduced volatility. Engineering teams select chain length and reactivity according to final viscosity and compatibility with target machinery. Strict adherence to technical product certifications and toxicological thresholds protects workers and downstream ecosystems in high-use industrial settings. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Plasticizer Precursor in Polymer AdditivesIn rigid and flexible PVC, polyurethane, and thermoplastic elastomer production, 1,2-Dodecanediol provides a high-molecular-weight polyol component for plasticizer and flexibility enhancer synthesis. Downstream manufacturers integrate this compound to tune cold flexibility, migration resistance, and aging characteristics while minimizing phthalate content. Custom compounding operations rely on batch-to-batch reproducibility to meet demanding physical and environmental specifications, ensuring supplier and user compliance within regulated sectors such as automotive interiors and child-safe plastics. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Pharmaceutical Intermediate for Active Ingredient SynthesisGMP-regulated manufacturers utilize 1,2-Dodecanediol as a critical synthetic intermediate in the preparation of specific long-chain glycolipids, antimicrobial agents, and as a fragment in API side-chain construction. Its chemical structure and high-purity profile enable predictable downstream synthetic yields with minimized by-product formation. Stringent procedural control ensures compliance with documented pharmacopoeial identities, elemental impurities, and process validation records as required by regulatory review for APIs, excipients, and specialty clinical trial materials. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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We have put decades into perfecting the production of 1,2-Dodecanediol. From raw material sourcing to final product packaging, every step relies on experienced hands and well-maintained processes. This gives our customers real consistency and purity. The chemical, also known as Lauryl glycol, sports a clear, viscous appearance, and brings C12 chain performance straight into your formulations. Our plant staff monitor each lot through a blend of traditional GC and advanced NMR—giving a purity above 98%, suitable for both high-performance polymers and cosmetics alike.
Longer alkane diols serve a specific need in the chemical and personal care industries. Demand for low-toxicity, biocompatible diols has risen as formulators look to replace shorter, more volatile molecules. The 1,2- isomer packs both primary and secondary hydroxyls on the C12 backbone, so you see smoother melting and easy processing. Our experience is that personal care companies search for alternatives to 1,2-hexanediol, often citing sensitivity and regulatory concerns. We manufacture this C12 version so material scientists, cosmetic chemists, and industrial users have another option to balance viscosity, low irritation, and gentle solvency.
1,2-Dodecanediol stands out because it is more hydrophobic than many shorter-chain diols. In our work with polymer emulsions, we have observed that the C12 backbone gives much better moisture resistance after curing. The same effect appears in personal care, where it acts as an emollient and preservative booster without stinging the skin—an issue some competitors have reported with its lighter cousins. Traditional glycols, including propylene or butylene glycol, bring stickiness or leave a filmy residue; the C12 chain reduces that tack without causing phase separation.
Our product development team includes both synthetic and application chemists who have worked with dozens of polyol structures. In our reactors, 1,2-Dodecanediol moves smoothly at moderate heat (melting point sits close to 45°C), maintaining full reactivity during polycondensation and esterification. We’ve seen our clients make flexible polyurethanes for coatings, soft and moisture-sealing plasticizers, and even adhesives where hydrolysis resistance matters. The diol’s hydroxyl groups stay available for further reactions, but its length means end products don’t yellow or become brittle over time—common complaints with shorter diols like 1,2-Octanediol or 1,2-Hexanediol.
Cosmetic chemists have told us that 1,2-Dodecanediol serves several roles—humectant, co-emulsifier, even gentle preservative. Microbial efficacy tests showed at concentrations above 0.5%, it knocks back bacteria and yeast populations better than pentylene glycol, while avoiding the stickiness or dryness sometimes caused by hexanediol. It also provides a skin-feel more similar to natural emollients, which matters in lotions and facial cleansers. By taking advantage of both hydroxyls, formulators can build stable emulsions—our pilot customers have proven this even in clear serum bases.
Our on-site quality team tracks each batch through the full production cycle. We check residual acid and water after distillation, since these two metrics affect shelf stability and performance—too much, and diols degrade or change color in long-term storage. Purity sits above 98%; moisture comes in at less than 0.2%. This matters, because industrial users have reported that off-spec raw materials from overseas vendors cause foaming and sticky processing lines. Night shift production crew see firsthand how correct distillation and handling avoid that outcome entirely. The process isn’t glamorous: it’s careful temperature management, clean transfer hoses, quality drums, and patience.
There’s a growing set of diols on the market, many of them C4–C8 based, targeting either cost savings or low odor. From years of bench testing, our team can say that 1,2-Hexanediol offers good antibacterial effects at lower concentrations, but irritancy on sensitive skin crops up nearly twice as often compared to 1,2-Dodecanediol. 1,2-Octanediol sits closer to ours in terms of performance, but it tends to increase formulation viscosity and can crystallize in cool conditions. Our C12 product packs more molecular weight, so migration rates in coatings drop, and wash-off in shampoos and face cleansers decreases. This point particularly matters for clients working with rinse-off or leave-on formulations, where performance sometimes gets lost down the drain.
Solubility profiles also differ: the C12 backbone resists simple water blends, so we work closely with customers to recommend suitable co-solvents or emulsifiers. Lab results and side-by-side emulsification trials show that careful pH control and slow addition help create stable systems. Our customers tell us that, for their premium applications—pharma-grade hand sanitizers or specialty facials—this small adjustment delivers the performance they need. Our production technicians can tailor crystalline size and melting point within a narrow range, so solid or flaked material flows easier on automated lines. Every batch we ship comes with a full COA and technical backup, based on thousands of hours running this chemistry.
While the market has shifted toward gentle, sustainable materials, 1,2-Dodecanediol aligns with the trend. Our supply chain and regulatory team pay close attention to compliance, particularly in markets that expect the lowest possible impurities (including REACH, EPA, and Asian regulations). Our process does not rely on animal-derived raw materials—everything used down the chain starts with plant or synthetic origins. Several of our clients in hair care and skincare report that their finished goods containing 1,2-Dodecanediol cleared EU allergen screening more smoothly than those using shorter-chain glycol blends.
From a handling perspective, the chemical does not float away or evaporate when open to air, and does not form fine dust. Workers at our factory have never reported eye or skin irritation under normal use. Still, we recommend gloves and goggles since pure diols can de-fat skin with extended contact. Toxicology profiles confirm low absorption and rapid excretion, so converters and packers don’t face cumulative exposure risk over the course of production or filling. Disposal as non-hazardous organic waste remains acceptable in most regions, but we recommend consultation for local practices.
Our most successful applications come from close collaboration with customers, not simply shipping a chemical and moving on. A coatings producer in East Asia sent us samples of 1,2-hexanediol blends that failed high-humidity exposure—after switching to our C12 material, their internal stress tests showed double the water resistance at half the loading. Similar stories come from cosmetic labs in Europe where formulators worried about greasy feel or preservation efficacy; small trials gave them softer skin feel and passed challenge tests with lower overall cost since the material carried both emollient and preservation strength.
We have seen common pitfalls: overuse of co-solvents for C12 can make formulations too thin, or choosing the wrong phase for addition during blending can cause haze or instability. Our teams work with blending operators, sharing data and tried-and-true mixing routines. These details carry weight. Formulators sometimes worry about odor—a minor, slightly fatty smell is typical for pure product, but does not show up in finished goods. Draining and storage of large volumes during cold weather can create solidification in pipes. Our engineering staff regularly consults on line heat-tracing and drum rotation to prevent this inconvenience.
A chemical is only as good as its source, and repeated incidents in the market have shown what happens when trace contaminants creep in from uncontrolled production. As a business that actually runs reactors, distillation units, and dryers, we speak from firsthand experience, not reseller summaries. Our creative R&D team, quality staff, and application chemists work as one, making sure the produced material really does what our data sheets say. There have been times when a critical impurity pattern showed up on GC, and instead of passing it on, we stopped production and retreated upstream to address it. That remains rare, but it sets a standard our competitors struggle to match.
Many traders and brokers repackage, and sometimes white-label products from random regional plants. As an actual manufacturer, we see every drum, every lot, and have skin in the game—our name and reputation go out with every shipment. It isn’t just about technical values but the confidence our partners can place in daily deliveries. Questions about batch-to-batch color drift, off-odor, or seasonal viscosity are routed directly to the processes and hands that ran the last charge. So customers are never left to wonder if supply problems will catch them off guard.
Growth in both the cosmetics and industrial sectors drives more demand for safe and high-purity alkanediols. This brings pressure on upstream raw material supply, logistics, and energy use. The spike in freight rates over the past two years tested our resolve; we buffered stock at local depots, and committed to slower but steadier deliveries over cost cutting and shortcuts. Input costs rose, particularly for hydrogen and specialty catalysts. Instead of reducing production quality, we trimmed plant utilities elsewhere, and invested in higher yield per batch.
Some challenges remain. Biobased routes for C12 alcohols look promising, but today, most economical processes still rely partially on petrochemical streams. We participate in technical collaborations and pilot alternative synthesis, but large-scale adoption remains a key goal. Customer pressure for lower carbon footprint packaging led us to switch to recyclable and returnable polymer drums. Worker safety requirements become stricter every year—we do not cut corners, running annual training and third-party audits.
We continue to explore better synthesis routes, higher purity fractions, and co-products for broader use. Market feedback points to opportunities in drug delivery, antimicrobial coatings, and advanced adhesives. Our own R&D program rolls on—it’s about 30% customer-driven, and 70% internally sparked by the “what if” questions that come up in plant meetings. We stand ready to share this molecule’s potential with new partners exploring fresh applications.
Years of hands-on practice and long cycles of customer feedback have shaped our knowledge and approach. Unlike actors further down the distribution chain, we see both the triumphs and the little failures firsthand. Knowing this lets us refine every process, listen better, and make improvements that simply stick. For companies seeking a trustworthy partner—not just a nameless bag of white powder—experience and technical integrity make the difference.