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1,2-Diphenyl-Butan-1-One

    • Product Name 1,2-Diphenyl-Butan-1-One
    • Einecs 211-591-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    231141

    Name 1,2-Diphenyl-Butan-1-One
    Molecular Formula C16H16O
    Molar Mass 224.30 g/mol
    Cas Number 17360-41-7
    Appearance White to off-white solid
    Boiling Point 397.5 °C at 760 mmHg
    Melting Point 54-57 °C
    Density 1.08 g/cm³
    Solubility In Water Insoluble
    Iupac Name 1,2-diphenylbutan-1-one
    Smiles CCC(C(=O)c1ccccc1)c2ccccc2
    Refractive Index 1.579
    Flash Point 187.2 °C
    Storage Conditions Store at 2-8 °C

    As an accredited 1,2-Diphenyl-Butan-1-One factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White plastic bottle with secure screw cap, labeled "1,2-Diphenyl-Butan-1-One, 100g," hazard symbols, batch number, and supplier details.
    Shipping **Shipping Description for 1,2-Diphenyl-Butan-1-One:** Shipped in tightly sealed, chemical-resistant containers, 1,2-Diphenyl-Butan-1-One should be protected from moisture, heat, and direct sunlight. Transport in compliance with relevant chemical handling regulations, including proper labelling. Avoid contact with strong oxidizers. Use secondary containment to prevent leaks or spills during shipping. Handle with appropriate personal protective equipment.
    Storage 1,2-Diphenyl-Butan-1-one should be stored in a tightly sealed container in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizers. Protect from moisture, direct sunlight, and excessive heat. Proper chemical labeling and secondary containment are recommended to prevent accidental exposure or spillage. Always follow relevant safety protocols and local regulations.
    Application of 1,2-Diphenyl-Butan-1-One

    Applications of 1,2-Diphenyl-Butan-1-One in Industrial Manufacturing

    As a direct manufacturer of high-purity 1,2-diphenyl-butan-1-one, we supply this specialty intermediate to select advanced downstream industries that require strict quality control and compliance. Our technical and QC teams work closely with downstream partners to ensure precise formula integration in line with local and international standards. Below, we present key application scenarios, illustrating how this compound contributes to sector-specific products and processes.

    1. Pharmaceutical Intermediate for Active Pharmaceutical Ingredient (API) Synthesis

    Our material serves as a crucial ketone building block in the synthesis of non-steroidal anti-inflammatory API candidates, among other specialty pharmaceuticals. Process engineers introduce the compound during vital condensation or reductive amination stages, constructing core molecular scaffolds central to the final API structure. Our production ensures trace impurity control, matching stringent regulatory and pharmacopeial accuracy goals required by global medicine manufacturers.

    Industry compliance standards

    • ICH Q7A: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (Ph. Eur.) monograph guidance for raw material acceptability
    • United States Pharmacopeia (USP) General Chapter <761> for impurity profiles
    • 21 CFR Part 210/211 (FDA cGMP regulations for pharmaceutical manufacturing)

    Typical usage ratio

    • Usually 8–15% molar ratio in relation to the total starting substrate in condensation or amination steps; chemists may refine this loading based on API yield targets and impurity constraints

    Downstream process integration

    • Added post-initial substrate activation in API assembly; reacts under controlled conditions with amine or aldehyde partners to construct intermediate compounds ahead of final API elaboration

    Final product types

    • Non-steroidal anti-inflammatory drug APIs
    • Synthetic analgesics precursors
    • Chiral pharmaceutical intermediates for pain management and inflammation therapy

    2. Fine Fragrance & Aroma Chemical Synthesis

    Many established aroma chemical producers select our compound as an essential intermediate to develop complex musky and balsamic fragrance molecules. Technologists rely on its specific ketone functionality during Friedel-Crafts alkylation or subsequent Grignard processes to achieve desired aromatic profiles. Its purity plays a vital role in both olfactory clarity and downstream shelf life stability, making it indispensable in luxury scent formulation chains.

    Industry compliance standards

    • IFRA (International Fragrance Association) Standards for raw material safety
    • EU REACH registration, evaluation, authorisation, and restriction
    • ISO 9235 (Aromatic Raw Materials for Fragrance Industry)
    • Good Manufacturing Practice under IFRA/ISO 22716

    Typical usage ratio

    • Usually 5–12% by weight within aroma intermediate batch, fine-tuned according to final fragrance building block requirements and desired note strength

    Downstream process integration

    • Reacted with substituted aromatics or alcohols under catalysed conditions during mid-stage synthesis of musky base notes; enters post-nitration workflow, prior to esterification or acetylation

    Final product types

    • Fine fragrance base ingredients for perfumes
    • Specialty musky aroma isolates
    • Premium flavor and fragrance compound intermediates

    3. Specialty Polymer Modifier in Engineering Plastics

    Major engineering polymer manufacturers leverage our ketone derivative as a chain extender and property modifier during the production of high-performance plastics, such as PBT (polybutylene terephthalate) and specialty polyamides. Its specific molecular structure enables controlled influence over polymer crystallinity, impact resistance, and melt processability. Our QC-certified product ensures the absence of residual solvents and meets polymer grade material demands for technical, automotive, and electronics applications.

    Industry compliance standards

    • ISO 9001:2015 (Quality Management Systems)
    • UL 94 for plastic flammability
    • RoHS Directive (2011/65/EU) for restricted substances control
    • REACH compliance for polymer producers in the EU

    Typical usage ratio

    • Incorporated at 0.2–2.5% by weight within polymer resin blends, depending on target physical property modification and specific melt viscosity requirements for extrusion or injection molding

    Downstream process integration

    • Direct blending into prepolymer or copolymer feed streams prior to melt-extrusion or reactive extrusion; carefully dosed during compounding to ensure homogeneous distribution and reproducible property enhancement

    Final product types

    • Impact-modified polybutylene terephthalate (PBT) granules for automotive and electrical housings
    • Specialty polyamide (PA) engineering components
    • High-performance extrusion grades with tailored crystallinity profiles

    4. Photoinitiator Intermediate for UV-Curable Systems

    Downstream photoinitiator manufacturers use our ketone as a controlled precursor in the synthesis of Type I or II photoinitiators, which enable UV curing in coatings, inks, and adhesives. Its defined aromatic ketone structure provides reliable reactivity with benzil or dialkoxybenzenes in standard condensation protocols, ensuring consistent photophysical properties for the finished initiators and stable UV performance in high-throughput industrial curing lines.

    Industry compliance standards

    • ISO 22517 (UV Curing Materials and Systems)
    • SGS Certification for absence of hazardous photolytic byproducts
    • FDA 21 CFR 175.300 for coatings in food contact applications (where relevant)
    • ASTM D7767 for cured film performance and migration

    Typical usage ratio

    • Occupies 9–18% of the mass balance in the core photoinitiator intermediate synthesis; actual composition varies depending on target UV absorption profile and crosslinking intensity specification

    Downstream process integration

    • Reacted via acylation or etherification during advanced initiator manufacturing; material is introduced after the formation of the initial aryl backbone, typically in controlled reactor environments to suppress by-product formation and ensure photoinitiator purity

    Final product types

    • UV-curable coating photoinitiators for electronics and automotive finishes
    • Photoinitiators for inkjet and offset inks
    • Advanced adhesive photoinitiators for high-speed packaging lines
    Free Quote

    Competitive 1,2-Diphenyl-Butan-1-One prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    1,2-Diphenyl-Butan-1-One: Meeting Demand with Genuine Chemical Craftsmanship

    Trust in the Source—Why Manufacturer Experience Matters

    Years have rolled by with us in the lab and on the plant floor, and 1,2-Diphenyl-Butan-1-One has led its fair share of batch logs and customer queries. This isn’t a product that gains attention simply through trends or the push of a distributor. Our customers—ranging from specialty materials firms to pharmaceutical scientists—bring real requests because consistent, uncompromising purity shapes the outcome of their work. Each kilogram of this compound reflects our commitment to transparent processes, from raw material selection to the checks that keep off odors, traces of colored byproducts, or inconsistent melting points.

    Specification—The Details Chemists Watch Every Day

    Let’s get into what matters. Our 1,2-Diphenyl-Butan-1-One, model DIPO-12B-2302, passes an HPLC purity threshold of 99.4% in routine lots, a mark we don’t compromise on, because even a slight impurity can easily throw off further synthesis. Moisture levels in the final product run below 0.2%, as any spike there can spark off-course reactions or instability under storage. We confirm molecular weight with each lot via LC-MS, ensuring what we send out matches client expectations, not only on paper but also in performance.

    We don’t treat particle size or crystalline form as background details. Many clients dial in for a specific granulometry—finer powder for pharmaceutical intermediates or chunkier crystals for custom syntheses. We follow through on those requests, handling the drying process with close-eye observation to maintain physical properties batch after batch. Quality doesn’t need translation when you see lot numbers and analyses that match experience in the field.

    Typical Usage—Real Tasks, Not Marketing Buzzwords

    1,2-Diphenyl-Butan-1-One features in research and commercial flows that have shaped its value over decades. In one stream, it becomes a building block for active pharmaceutical ingredients—especially where side-chain extension or aromatic functionalization is needed. Medicinal chemists rely on its carbonyl group, combining quickly with various nucleophiles and providing a straightforward path to designer molecules.

    Outside pharma, we see requests from those working in advanced materials. The compound’s backbone offers rigidity and stability that suit its inclusion in specialty polymers and resin intermediates. When working up functional surfaces with aromatic character, material science teams come calling and trust the precise specification because their R&D budgets cannot handle uncertainty or post-purchase troubleshooting.

    Industrial users incorporate 1,2-Diphenyl-Butan-1-One into custom flavor and fragrance syntheses, exploiting the molecular structure to introduce both bulk and subtlety to complex blends. We don’t deny that every once in a while a new field makes a call—cosmetic developers, pigment formulators, even academic researchers who want nothing more than a reliable, documented, reproducible batch.

    Not Just Another Ketone—Key Differences from Lookalike Chemicals

    Plenty of aromatic ketones cycle through laboratories, but 1,2-Diphenyl-Butan-1-One carves out a space in both reactivity and practicality. Take benzophenone: a workhorse in its own right but entirely different in chemical behavior, reactivity with nucleophiles, and end-use performance. The butyl chain in our compound, capped by a second phenyl, transforms not only its solubility but also how it fits into longer synthetic schemes.

    Compare this to acetophenone, often subbed in without thought. Acetophenone’s single phenyl group and shorter side chain limit the structural complexity downstream—whereas a batch of 1,2-Diphenyl-Butan-1-One opens doors to more elaborate frameworks. Our teams have worked out roots and branches of these synthetic trees for years; seeing how customers utilize such flexibility is one of the small satisfactions of the job.

    Other substituted butanones, like 2,3- or 3,4-diphenyl analogs, don’t deliver the same mix of rigidity and extension for target molecules. Structural isomerism isn’t a footnote here; it drives solubility in process solvents and can make or break the formation of crystallized end products. We collaborate closely with downstream users in polymers, fine chemicals, and pharmaceutical sectors to select the right positional isomer—cutting down unnecessary attempts in the lab, and sparing everyone time and wasted stock.

    Real-World Production—How Manufacturing Choices Shape Quality

    There’s a difference between a batch run for demonstration, and a full-scale campaign for real-world customers. In our operation, we choose routes that prioritize safe conditions and manageable waste, steering away from older methods using excessive reagents or catalysts with disposal headaches. Yield matters, but downstream purity ranks even higher. Using chromatography and careful crystallization, we limit byproducts often left unchecked by less robust syntheses—saving end users hours of purification headaches.

    Quality doesn’t stabilize by wishful thinking. Frequent sampling, attention to filtration, and staff who know the significance of subtle spectral changes mark the manufacturing side. Glancing over a GC trace, techs catch minor impurities before they ever reach the fill line, and every anomaly traced to its source before shipment. This watchfulness isn’t about branding; it keeps actual production goals—for the smallest labs and large pilot plants—on target.

    Validation—Building Confidence Beyond the COA

    Many buyers trust a certificate of analysis, but field veterans know the origins of a lot, the dates of manufacture, even the batch notes matter. Each lot receives verification steps including melting point, spectral NMR, and sometimes customer-specified HPLC methods outside our standard routine. For order runs above 20 kg, we invite representatives to observe inspection and sampling directly in the plant. Confidence builds in sample rooms with eyes on the product, not just from email PDFs.

    Experience tells us trace residual solvent can linger in poor-quality production. Our team applies vacuum processing and skilled drying for each batch, supported by headspace GC-MS validation that keeps undesirable residues at bay. It’s this day-to-day practice—not grand claims—that shields the final user from process upsets or batch failures.

    Consistency Starts with Raw Materials

    Feedstock reliability echoes through every downstream stage. We order benzhydrol and 1-phenylbutanone in bulk from audited suppliers, insisting on analytical-grade starting points with strict impurity limits. Any deviation—an off-color, a mild scent, a tank scum—results in immediate rejection and a review with the supplier. Our incoming goods lab handles spectrophotometry and trace analysis on every received drum, feeding insights back into our own and our vendors’ QA programs.

    Supply chains face pressure from many sides, including political shifts and logistical crises. Unlike traders or resellers, we keep buffer stocks of key reagents and maintain backup sources with documented histories. We live with the reality of late shipments and occasional price spikes, but this approach keeps customer production flows uninterrupted and provides a level of assurance unavailable to those ordering hand-to-mouth.

    Waste, Safety, and Environmental Commitment

    Long-term stewardship counts here, not only to meet regulatory files but to protect the site and staff who rely on this workplace. Recrystallization and solvent management don’t leave residues to chance; aqueous and organic layers find separate collection, and waste batches clear through third-party auditors. Our usage of process solvents traces a closed-loop system whenever technology allows, and we recycle or neutralize at-site to keep output within legal and ethical limits.

    For operators and R&D teams, exposure control—a topic less popular for outside copywriters—means cool, dust-free transfers, local exhaust systems, and continuous training. Our safety walkdowns follow not just government regulation but best-practice benchmarks set by chemical industry peers. Teams monitor every transfer, limiting exposure to airborne particles and maintaining transparent accident logs visible to all staff.

    Supporting Customers with Real-World Knowledge

    We keep lines open for questions about route selection, purification schemes, and end-use compatibility. Technical feedback doesn’t pass through layers of go-betweens, giving customers the benefit of real experience with the compound’s quirks and tips for process success. Feedback from longtime partners often leads to a tweak in an operation—sometimes a drier switch or a grind setting adjustment—because they trust the chemists who have delivered clean material through years of seasonal and demand swings.

    We learn with each tough synthesis and every report back from a customer who hit an obstacle or a failed reaction. That experience weaves into each campaign, grounding our advice in what works, not wishful thinking or marketing hyperbole. If a solvent system or a workup fails in one field, it often echoes elsewhere—meaning the guidance we provide today draws not only from analytical data, but also from cumulative, on-the-floor adjustments.

    Stock, Shipping, and the Value of Predictable Partners

    We schedule production windows for 1,2-Diphenyl-Butan-1-One that balance regular clients with new inquiries, hedging against the real-world unpredictability of demand. Each lot packs into lined, heavy-sealed drums that resist moisture and transit abrasion. Documentation travels ahead of the bulk shipment, offering content transparency, batch trace data, and guidance on preliminary handling.

    Shipping isn’t an afterthought. We partner with established chemical logistics firms, maintain compliant packaging for IATA and IMDG shipments, and prioritize clear, complete customs paperwork. For sensitive clients—those faced with regulatory or inspection challenges—we offer direct dialogue with our compliance staff, slashing delays and ensuring the right analytical files accompany each order.

    What Reliable 1,2-Diphenyl-Butan-1-One Means for Industry

    The market still holds space for those who understand what a manufacturing pedigree brings to a specialty chemical. Our decades in synthesis set expectations that others struggle to meet, especially for clients weighing risk versus reward in pharmaceutical, industrial, and materials projects. The difference lies in every clean spectrum, every tracked impurity, and in feedback that makes the next batch better. This isn’t about selling a molecule; it’s about delivering an experience that builds trust, keeps projects on schedule, and opens real innovation.

    We see our role not as intermediaries, but as partners invested in each client’s success—from model development and custom specs, to addressing the curveballs of modern markets. That’s the value of true manufacturing expertise: working through variables side by side, striving for enduring quality, and making sure every shipped kilogram earns its place and reputation in your lab or plant.