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1,2-Dichloro-3,3,3-Trifluoro-2-(Trifluoromethyl)Propane

    • Product Name 1,2-Dichloro-3,3,3-Trifluoro-2-(Trifluoromethyl)Propane
    • Alias Freon 1233zd
    • Einecs 425-090-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    838245

    Chemicalname 1,2-Dichloro-3,3,3-Trifluoro-2-(Trifluoromethyl)Propane
    Casnumber 460-35-5
    Molecularformula C4H2Cl2F6
    Molecularweight 246.96 g/mol
    Appearance Colorless liquid
    Boilingpoint 55-56 °C
    Density 1.569 g/cm3 (20°C)
    Refractiveindex 1.343 (20°C)
    Flashpoint Non-flammable
    Solubilityinwater Insoluble
    Vaporpressure 306 mmHg (25°C)
    Synonyms HCFC-226cb, Halon 226cb

    As an accredited 1,2-Dichloro-3,3,3-Trifluoro-2-(Trifluoromethyl)Propane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 100g quantity of 1,2-Dichloro-3,3,3-Trifluoro-2-(Trifluoromethyl)Propane is packaged in a sealed amber glass bottle with hazard labeling.
    Shipping 1,2-Dichloro-3,3,3-trifluoro-2-(trifluoromethyl)propane should be shipped in tightly sealed containers, clearly labeled, and transported in compliance with chemical and hazardous materials regulations. Avoid sources of ignition, extreme temperatures, and direct sunlight. Ensure appropriate documentation, including Safety Data Sheets (SDS), accompanies the shipment for safe handling and emergency response.
    Storage Store **1,2-Dichloro-3,3,3-trifluoro-2-(trifluoromethyl)propane** in a cool, dry, well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers. Keep container tightly closed and clearly labeled. Protect from physical damage, direct sunlight, and moisture. Ensure storage area is equipped with proper spill containment and safety measures. Use appropriate corrosion-resistant containers.
    Application of 1,2-Dichloro-3,3,3-Trifluoro-2-(Trifluoromethyl)Propane

    Applications of 1,2-Dichloro-3,3,3-Trifluoro-2-(Trifluoromethyl)Propane in Industrial Manufacturing

    As the direct manufacturer of 1,2-Dichloro-3,3,3-Trifluoro-2-(Trifluoromethyl)Propane, we supply this high-purity specialty fluorinated intermediate for industrial clients in select, highly-regulated application streams. The chemical’s specific reactivity, physical constants, and trace profile control our established partnerships in advanced sectors. Below is a detailed application portfolio developed through technical support and feedback from global users and production scale integrators.

    1. Refrigerant Blends and HFO Synthesis

    Producers of next-generation refrigerants incorporate this compound primarily for use in hydrofluoroolefin (HFO) synthesis, where its high fluorine content supports the construction of low-global-warming-potential (GWP) blends. In these applications, our material’s consistent halogenation assists in generating target purity under continuous-feed, gas-phase fluorination. Downstream partners demand strict lot-to-lot reproducibility and impurity mapping to meet environmental and safety certifications for the refrigerant sector.

    Industry compliance standards

    • AHRI 700-2022 (Refrigerant Purity Specification)
    • EN 378-1:2016 (Refrigerating systems and heat pumps)
    • REACH registered for intermediate use
    • ISO 14067:2018 (GWP life-cycle reporting)

    Typical usage ratio

    • Ranges from 5–15% as a feedstock in fluorination networks
    • Adjusted against flow rates, target composition, and reactor yields for proprietary refrigerant formulas

    Downstream process integration

    • Continuous or batch-reaction vapor phase fluorination
    • Fed via closed-loop dosing systems at controlled temperature and pressure
    • Monitored in-line for hydrolysis or decomposition products

    Final product types

    • HFO-1234yf and related low-GWP refrigerants
    • Specialty refrigerant blends for automotive or commercial use
    • Climate-safe propellant mixtures

    2. Agrochemical Intermediate for Advanced Crop Protection Molecules

    Agrochemical formulators purchase this compound as a high-value building block for selective fluorination reactions in the synthesis of specialty herbicides and insecticides. Its functional groups enable site-selective halogen incorporation, critical for regulatory accepted toxicological and environmental fate properties. We support customers’ process validation and analytical confirmation for production scale-up.

    Industry compliance standards

    • FAO/WHO Specifications for Pesticides
    • ISO 9001:2015 certified quality system
    • Regulation (EC) No 1107/2009 (Active ingredient approval, Europe)
    • Good Manufacturing Practice (GMP) Guidelines for active ingredient intermediates

    Typical usage ratio

    • Inserted at 3–12% by mass in stepwise halogen exchange and coupling synthesis lines
    • Ratio determined by crop protection molecule target structure and required degree of fluorination

    Downstream process integration

    • Halogen exchange reactions in agchem synthesis blocks
    • Integrated in multi-step batch or continuous processes
    • Strict control of exothermic release and reagent residue

    Final product types

    • Trifluoromethyl-substituted herbicides
    • Highly selective insecticide actives
    • Next-gen fungicide intermediates

    3. Polymerization Modifier for High-Performance Fluoropolymers

    Producers of speciality fluoropolymers utilize this raw material as a chain-transfer agent or functionalized comonomer for tailored physical properties. Its electron-withdrawing chlorofluoro groups enable fine adjustment of dielectric constant, chemical inertness, and surface energy in engineered polymer resins, essential for high-value end-uses in cable insulation, gaskets, and semicon packaging.

    Industry compliance standards

    • ASTM D2116 (Standard Specification for PTFE Resin)
    • RoHS Directive (2011/65/EU) for halogen content
    • UL 94 (Plastic Flammability Rating)
    • IATF 16949:2016 (Automotive polymer applications)

    Typical usage ratio

    • Dosed at 0.5–3.5% by mass during co-polymerization steps
    • Optimized for mechanical strength, melt flow, and thermal resistance targets

    Downstream process integration

    • Continuous or batch reactor polymerization
    • Controlled feeding to minimize undesired molecular weight broadening
    • Analytical QC on residual chlorine/fluorine content

    Final product types

    • High-performance fluoropolymer resins
    • Fluorinated cable insulation compounds
    • Gasket and seal base materials for extreme environments

    4. Electronics-Grade Cleaning Agent Precursor

    Manufacturers in semiconductor and precision electronics processing rely on this compound as an intermediate for synthesizing high-purity, low-residue solvent agents. Its controlled halogen profile allows downstream producers to achieve stringent metal and ionic impurity specifications demanded by wafer fabrication and display manufacturers, supporting defect reduction and enhanced component longevity.

    Industry compliance standards

    • SEMI C93 (Test methods for solvent purity)
    • IEC 62474 (Material declaration for electronics)
    • ISO 14644-1:2015 (Cleanroom standards)
    • JIS K 0102:2016 (Testing methods for industrial chemicals)

    Typical usage ratio

    • Generally batched at 2–6% by process mass during cleaning agent synthesis
    • Adjusted for aggressivity, volatility, and compatibility with sensitive materials

    Downstream process integration

    • Synthesized into precision cleaning fluids by nucleophilic substitution or reduction
    • Integrated into solvent blend lines under inert atmosphere
    • Filtered and packed for ultra-high-purity grades

    Final product types

    • Wafer cleaning agents for semiconductor fabrication
    • High-reliability PCB cleaning solvents
    • Display glass degreasing agents

    5. Specialty Chemical Synthesis for Pharmaceutical Impurities Reference

    Pharmaceutical reference labs and active ingredient manufacturers procure this intermediate for use in synthesizing well-defined impurities, reference standards, and toxicological markers. The unique structure provides required halogen substitution essential for regulatory analytical validation and forced degradation studies tied to novel API registration or patent submission processes.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for APIs)
    • USP General Chapter <232> (Elemental Impurities)
    • Pharmacopoeia monograph requirements (as applicable by region)
    • FDA 21 CFR Part 211 (Finished Pharmaceuticals GMP)

    Typical usage ratio

    • Synthesized in micro-scale: 0.3–2% of target batch, depending on impurity profile
    • Ratio selected by desired reference concentration and analytic calibration values

    Downstream process integration

    • Entry in multi-step organic synthesis or halogenation
    • Purified to sub-ppm trace levels for reference use
    • Verified by NMR, MS, and HPLC for identity and purity

    Final product types

    • Pharmaceutical reference standards
    • API-related impurity mixtures
    • Analytical markers for regulatory approval files
    Free Quote

    Competitive 1,2-Dichloro-3,3,3-Trifluoro-2-(Trifluoromethyl)Propane prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    1,2-Dichloro-3,3,3-Trifluoro-2-(Trifluoromethyl)Propane: An Insider’s Perspective from the Factory Floor

    We wake early for the morning shift, well aware that every day in a chemical plant means managing precision. Technicians measure, clean, and align their instruments because the output from each reactor must be consistent; a single miscalculation can change the character of a compound. Down on the production line, 1,2-Dichloro-3,3,3-trifluoro-2-(trifluoromethyl)propane has taken its place among our more rigorously engineered organofluorine intermediates, showing an adaptability in chemical synthesis that many of us appreciate after years in this business.

    Understanding the Compound’s Build

    Our teams synthesize this compound with its distinctive dual halogen and heavy fluorine composition. The molecular structure—thick with halogen content—originates from tightly managed batch reactions. This dual chlorination, combined with six fluorines stacked across the carbon backbone, creates a profile that resists thermal breakdown and keeps the molecule stable across a broad spectrum of conditions. Measuring tightly for impurities, our lab confirms that each batch delivers the purity process engineers need. Too many by-products and you lose yield. We have learned, sometimes the hard way, that only steady control of temperature, reactant ratios, and solvent clarity will give us a reliable product.

    Specification Details and Transparency

    Every drum we move off the line is expected to meet strict in-house purity thresholds. This means typical GC analysis puts our purity consistently above 98%. Our most seasoned operators know by sight and smell when a batch deviates. Once, a pressure valve failed late at night and, without correct response, a run dropped to 94%, resulting in a week of remediation. Small details matter—moisture content, residual solvent, possible isomerics. We analyze all these before letting any product leave our hands.

    Packing comes in stainless-lined drums or antistatic totes. These prevent surface interactions that could threaten product stability. In the shipping area, we’ve made changes over the years. Early shipments once triggered spontaneous off-gassing in warm climates; new temperature controls and custom-fitted tankers mean we now handle much less customer feedback on leakage or trace decomposition.

    Daily Application in Industry

    Looking at the buyers who use our 1,2-dichloro-3,3,3-trifluoro-2-(trifluoromethyl)propane, the demand mostly comes from specialty chemical companies looking for high-performance precursors. This compound finds its value as a strong building block in the creation of fluoropolymers, specialty refrigerant intermediates, and select agrochemical synthesis chains. Workers on the customer side tell us that our product helps them bypass some purification stages, saving on energy and operational costs. Engineers adjusting reaction profiles in their own plants run side-by-side tests and often call our QC group, asking if the minor residuals could interfere with their catalysts or downstream yields.

    Some have adapted our compound for the manufacture of advanced fluorinated lubricants and high-voltage dielectric insulators. We receive questions on thermal stability under arcing loads and see the data return from field performance. A recent feedback cycle with a European electronics company led to a close look at trace metal contamination; we made alterations in cleaning protocols, cutting residuals down to the low ppb range.

    In the Field: Real Challenges, Real Fixes

    Years of production have taught us that not every facility can accommodate a new fluorinated intermediate without training. Customers switching from traditional hydrocarbon or mono-fluorinated molecules often miss the increased reactivity and volatility found here. On-site audits and walk-throughs with our own chemical engineers have solved issues ranging from solvent compatibility to storage tank lining failures. There was a case with a client who, unused to this compound’s density and low-temperature viscosity, found their pumps straining every week. Joint investigations led to new transfer protocols and revised heating schedules, reducing equipment downtime.

    Another important difference: our compound boasts a much lower potential for environmental release compared with older chlorinated solvents. After new global regulations started pinching some of our longstanding customers, many adjusted their process chemistry. They needed a drop-in substitute but refused to compromise on profile or stability. We argued hard in meetings with both site safety officers and compliance coaches that the mass balance and atmospheric persistence profiles compared favorably; in time, regulatory filings confirmed the shift caused fewer disclosures and improved downstream waste management.

    Comparison with Related Compounds

    We often face direct comparisons with 1,1,1,3,3-pentafluoropropane or similar chlorofluorinated gases. Colleagues in R&D labs run them side by side, chasing deviations in boiling point, solubility, or ozone reactivity. From production records, we see the differences reflected in heat exchange reactions. For example, 1,2-dichloro-3,3,3-trifluoro-2-(trifluoromethyl)propane holds up better in reactions demanding high resistance to free-radical chain cleavage. We see less discoloration, lower rates of acid by-product formation, and a firmer yield retention. Production workers that once struggled with batch contamination from similar products now see longer reactor run times and less mid-cycle maintenance.

    The difference in cost takes careful workflow analysis. Other manufacturers still attempt to use lower-fluorinated analogues, drawn in by the cheaper starting materials and simpler processing. Over time, breakdown products and recurring need for rework or post-processing degrade the value. Real costs show up under the surface—scrap rates, higher labor expenses, shipment returns. Our internal audits show the more robust trifluoromethylated backbone pays for itself beyond the sale.

    Worker Safety and Environmental Considerations

    A modern plant doesn’t run without attention to worker safety. Our compound’s high halogen content means leaks require disciplined response. Eyes and skin get irritated quickly if a seal slips. We fitted new gas sensors and upgraded PPE standards after a minor incident, ensuring that newer team members recognized the hidden hazards. In my years on the site, we’ve trained more than a hundred crew in rapid shut-off and decontamination, often rehearsing late at night with drills. The safety data on this compound shows it doesn’t combine easily with atmospheric moisture, reducing secondary risk, but it does demand sealed storage and dry condition handling.

    Waste disposal changed after regulators flagged emissions in the early days. Solvent traps shifted to closed-loop recovery systems; residue is now passed through advanced scrubbers, minimizing both halogen and greenhouse gas discharge. These investments weren’t optional—city inspectors run unannounced air quality checks, and the public can see real-time stack readings online. We had to own that responsibility.

    At the environmental compliance queue, our emission records suggest that transitioning away from multichlorinated hydrocarbons allowed a measurable drop in soil and ground vapor incidents. Fewer hazardous waste designations speed site cleanup after product transfer. Periodic environmental audits now rate our operation much more favorably than those tasked with legacy compounds. This reassures community leaders as well as future hiring prospects—no one wants to sign on to a facility with a reputation for spills or complex remediation profiles.

    Customer Conversations: Real Needs, Real Constraints

    We listen to customer stories daily. One asked if a minor switch in additive packages would ease polymer compatibility; another wondered about refining the color index below an already strict requirement for optical applications. Not every request means another sales pitch. It’s about hearing the trouble spots—equipment fouling, by-product odors, maintenance backlogs—and then translating that pain into practical, achievable process fixes.

    One customer, facing repeated failures linked to seasonal humidity, called out our product’s resistance to atmospheric water absorption as a blessing. Another, after a series of process shutdowns, isolated a persistent trace contaminant to differing grades from various sources. Collaborating on test runs, we found tweaks in purification either solved their issues or redirected them to a new grade. Fact-based discussions trumped marketing every time.

    We field many questions about integrating our materials into existing regulatory or sustainability frameworks. Some clients need European REACH compliance reports, others face regional registration headaches in Asia. Our regulatory affairs team keeps thorough documentation, lab logs, and lot-level material histories. Inspectors often cite our cradle-to-shipment documentation as a model for transparent chemical stewardship. These aren’t abstract “value adds”, but a function of the real-world demands on operators juggling compliance, output, and workforce safety—all while keeping cost overruns to a minimum.

    The Manufacturing Mindset: Why We Emphasize In-House Production

    Supplying this compound as a direct manufacturer sets us apart from traders and repackagers. Every kilogram comes straight off our reactors, not relabeled from third-party swaps. If a batch registers off-spec—even in the hundredth decimal—we know fast. We invite third-party labs to audit our process, allowing customers to pull split samples right in the warehouse. This approach isn’t about boasting; it’s confidence in batch origin and performance—something harder to trace as chemical supply chains stretch longer across continents.

    Plant operators rotating through each division know precisely where to intervene if an anomaly surfaces. There’s a pride in drawing from our own reactors rather than relying on intermediaries. It means greater traceability, faster technical feedback, and, frankly, a stronger sense of control over every metric. Shipping direct also lets us adapt packaging formats and loading protocols quickly, responding to customer needs without the delay or risk of offsite repacking.

    Technical Partnerships and Product Evolution

    Collaboration pushes us to improve. Several R&D teams from our key customers send questions that we answer directly from the production floor or analytical labs. If a reaction yield slips or an unexpected impurity creeps in, we seek out root causes—reactor fouling, abnormal reagent profiles, off-standard temperature holds. After months of debate and lot-by-lot data review with a semiconductor firm, we re-engineered part of our purification cycle, extending the shelf-life far beyond the initial specification window.

    Experience building new chemical solutions means learning daily from direct customer feedback—new application tests, field failure reports, deeper performance metrics. Our lab couples analysis with the production side, running joint experiments on factors like pressure cycling or trace organics formation at elevated temperatures. If something’s not right, it’s our job to refine it, not wait for market trends to set engineering standards.

    This compound’s journey began as a niche replacement for older, problematic intermediates and now sees demand across electronics, agrochem, and specialty plastics sectors. Research partnerships with academia and select private labs bring new uses to light every year. As other manufacturers pivot to fluorination chemistry, our real advantage is standing behind each batch, rooted in hands-on expertise, not just lab theory or trading sheets.

    A View Beyond the Plant Gates

    External factors force continuous evolution—shifting end-user requirements, tightening national import rules, rise of green chemistry, even the unpredictable nature of global logistics. Manufacturing is about responding to these shifts without losing sight of quality, safety, or the unspoken promise to each customer. Facing a market shaped by fluctuating raw material prices and periodic shortages, we’ve built alternatives and developed contingency planning that ensures steady supply. Years of relationship management and raw material sourcing have allowed us to weather shocks that put traders and resellers on the defensive.

    Waste management and output efficiency concern regulators and stakeholders alike. Our experience tells us, efficiency at the plant floor directly translates to lower environmental load, fewer compliance headaches, and sharper cost controls. This aligns with broader company goals, including responsible production, cleaner emissions, and transparent communication throughout the supply chain.

    Why This Product Stands Out

    Through all cycles—ramp-ups, downturns, new regulation, or major upgrades—1,2-dichloro-3,3,3-trifluoro-2-(trifluoromethyl)propane stays on our books because it works, both in lab models and in the unpredictable world of full-scale production. The depth of field data, positive customer feedback, and robust in-house process control make it not just another chemical offering, but one built and refined by those who handle it daily.

    Customers working at the margins—to push their own technology or meet next-generation standards—find value in products backed directly by transparent manufacturing, open technical dialogue, and a willingness to adapt based on feedback, not just sales data. From our point of view, chemistry succeeds when those closest to the process own the outcomes and stand behind every shipment, knowing firsthand what it takes to deliver precision, day in and day out.