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1-(2-Bromoethyl)Naphthalene

    • Product Name 1-(2-Bromoethyl)Naphthalene
    • Alias 1-Naphthalenemethanamine, 2-bromo-
    • Einecs 259-454-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    201889

    Product Name 1-(2-Bromoethyl)Naphthalene
    Chemical Formula C12H11Br
    Molecular Weight 235.12 g/mol
    Cas Number 939-29-7
    Appearance Colorless to pale yellow liquid
    Boiling Point 328.6 °C (estimated)
    Density 1.39 g/cm³ (at 25 °C)
    Purity Typically ≥97%
    Refractive Index 1.622 (at 20 °C)
    Solubility Insoluble in water, soluble in organic solvents
    Storage Conditions Store at room temperature, in a tightly closed container
    Smiles Brc1ccc2ccccc2c1CC

    As an accredited 1-(2-Bromoethyl)Naphthalene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle labeled "1-(2-Bromoethyl)Naphthalene, 25g." Bottle features hazard symbols, lot number, and secure screw cap closure.
    Shipping 1-(2-Bromoethyl)Naphthalene is shipped in tightly sealed, chemical-resistant containers to prevent leaks and protect from light and moisture. Packaging complies with regulatory standards for hazardous materials. During transportation, it is labeled as a dangerous good, handled with caution, and accompanied by appropriate safety documentation and Material Safety Data Sheet (MSDS).
    Storage Store **1-(2-Bromoethyl)naphthalene** in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizing agents. Keep the container tightly closed when not in use and protect from direct sunlight. Properly label the container and ensure it is made of a material compatible with organic halides to prevent leaks or reactions.
    Application of 1-(2-Bromoethyl)Naphthalene

    Applications of 1-(2-Bromoethyl)Naphthalene in Industrial Manufacturing

    1-(2-Bromoethyl)Naphthalene is primarily used as a reactive intermediate in specialty organic synthesis. As a direct manufacturer, we supply this material for a range of industrial manufacturing segments where consistent quality and process-adapted specifications are critical.

    1. Agrochemical Intermediates Synthesis

    In the agrochemical sector, formulators use this compound as an alkylating agent for the production of substituted naphthalene derivatives. These derivatives function as key structural units in the synthesis of select naphthalene-based herbicides and fungicides, due to their stable aromatic framework and reactivity. Downstream agrochemical manufacturers incorporate it via controlled batch or semi-batch processes, typically under anhydrous and inert conditions, to prevent unwanted side reactions. Accurate metering of the reagent allows reliable chain extension and ring-functionalization, essential for specific active ingredient performance and registration requirements.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for chemical registration and evaluation
    • ISO 9001:2015 certified QMS for traceability and process control
    • Directive 91/414/EEC relating to the placing of plant protection products on the market (active substances)

    Typical usage ratio

    • 10–35% by mole in key naphthyl functionalization step, adjusted based on desired final active structure and targeted batch size

    Downstream process integration

    • Introduced at the nucleophilic substitution or alkylation stage prior to formulation of the active ingredient concentrate

    Final product types

    • Selective herbicides (naphthalene-based actives)
    • Aromatic fungicide actives

    2. Pharmaceutical Research Building Blocks

    Researchers and process development teams in the pharmaceutical industry utilize this chemical for synthesizing complex heteroaryl-pharmaceutical intermediates. Due to its halogenated ethyl side chain, it serves as a versatile precursor for constructing polycyclic scaffolds with precisely placed functional groups, especially in targeted oncology and neurology lead compounds. GMP pilot facilities source this compound for non-clinical and early-stage clinical route scouting, taking care to identify and purge trace-level impurities during process design and scale up.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients
    • USP-NF General Chapter <1078> for impurity profiles
    • 21 CFR Part 211 for manufacturing and process controls

    Typical usage ratio

    • 5–20% by weight of reaction mixture in initial step; lower percentages for scaffold elaboration in multistep synthesis

    Downstream process integration

    • Fed into Grignard or nucleophilic substitution pathways for linkage to form fused-ring intermediates

    Final product types

    • Small molecule API intermediates
    • Clinical trial candidate intermediates (oncology, CNS)

    3. Fine Chemicals and Specialty Dye Manufacturing

    Producers of performance dyes and fine aromatic chemicals apply this material to introduce a brominated ethyl group on naphthalene cores, achieving targeted color fastness and thermal properties. The compound supports synthesis routes for azo and anthraquinone derivatives, enabling further sulfonation or diazotization as dictated by end-user textile and plastics market requirements. Accurate weighing and staged addition into coupling or halogen-exchange reactions is required to obtain the specified chromophore purity and batch reproducibility.

    Industry compliance standards

    • Dyestuff Manufacturers Association Standards (as per country/region)
    • Oeko-Tex Standard 100 Annex 6 for restricted substances in textile colorants
    • ISO 14001:2015 for waste management in dye processing

    Typical usage ratio

    • 15–25% by mole relative to core naphthalene substrate in coupling reactions

    Downstream process integration

    • Charged into the halogenation or coupling reactor prior to final chromophore construction

    Final product types

    • Naphthyl-based azo dyes
    • Brominated anthraquinone pigments

    4. Advanced Polymer Additives Production

    Polymer compounders and additive formulators use this intermediate as a functional monomer or chain modifier to impart specific electronic and thermal properties to engineered resins. Its structure allows integration into poly(aryl ether) or polyester systems, with downstream modification enabling flame retardancy or enhanced mechanical strength for high-value plastics. Process managers meter the compound precisely in pre-polymer mixing steps; reactivity and purity must align with the required resin specification and downstream compounding process.

    Industry compliance standards

    • ASTM D5630 (Standard Test Method for Ash Content in Plastics) for quality control
    • EN 60335-1 (safety of electrical appliances) for flame retardant compounds
    • ISO 9001:2015 for process assurance

    Typical usage ratio

    • 2–8% by weight in polymer precursor mix; ratio tuned for target glass transition temperature or flame retardancy

    Downstream process integration

    • Added to reaction vessel during batch polymerization or pre-polymer modification before extrusion or molding

    Final product types

    • High-performance thermoplastic resins
    • Flame-retardant engineering plastics

    5. Organic Electronics and Material Science Synthesis

    Specialty manufacturers in the organic electronics field incorporate this compound as a precursor for synthesizing functionalized naphthalene derivatives suitable for organic light-emitting diodes (OLEDs) and organic semiconductor layers. The bromine center facilitates cross-coupling reactions such as Suzuki or Heck chemistry, allowing precise architectural control in π-conjugated systems. Material scientists carefully control stoichiometry and solvent composition to achieve targeted energy bandgaps and charge mobility in the final organic electronic material.

    Industry compliance standards

    • RoHS Directive 2011/65/EU for restricted hazardous substances in electronics
    • IPC-4101 for base materials in printed circuit applications
    • ISO/TS 80004-11:2017 for nanotechnology in material processing

    Typical usage ratio

    • 5–12% by mole in cross-coupling reactions; degree of polymerization and electronic target determine final ratio

    Downstream process integration

    • Feeding into palladium-catalyzed cross-coupling prior to thin film casting or device layer deposition

    Final product types

    • OLED host and emitter materials
    • Organic semiconducting films

    6. Laboratory-Scale Chemical Research and Development

    University and corporate R&D labs purchase this compound as a specialty reagent to test novel synthetic methodologies or to develop structural analogs for patent application studies. Its combination of halogen and ethyl substituents on the naphthalene ring allows chemists to explore regioselective functionalizations and extended aromatic frameworks. Research chemists must document handling and reaction conditions for reproducibility and compliance with institutional safety policies.

    Industry compliance standards

    • Good Laboratory Practice (GLP) for non-clinical experiments (OECD Principles)
    • Local chemical handling and disposal regulations (e.g., US EPA 40 CFR part 261)
    • Institutional Health & Safety Committee protocols

    Typical usage ratio

    • Variable; typically 0.1–1.0 mmol scale per experiment, adjusted per reaction optimization requirements

    Downstream process integration

    • Used as a reactant or reference material in synthetic route exploration, or mechanistic chemical studies

    Final product types

    • Patentable chemical structures
    • Reference standard samples
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    Certification & Compliance
    More Introduction

    1-(2-Bromoethyl)Naphthalene: The Value of Quality Manufacturing in Advanced Chemical Synthesis

    Seeing Chemistry at Work: Manufacturing Perspective

    On the shop floor, where the scent of solvents lingers and the hum of glass reactors sets the tempo, the job never boils down to simply reaching purity standards or checking boxes. In producing 1-(2-Bromoethyl)Naphthalene, hands-on experience shapes every decision, from solvent selection to the calibration of temperature curves. Precision goes beyond what the spec sheets describe, especially because researchers and process engineers rely on this compound to build more complex molecules. As a manufacturer, building trustworthy chemical building blocks means balancing innovation and discipline, batch after batch.

    What Sets 1-(2-Bromoethyl)Naphthalene Apart

    This naphthalene derivative stands out as a key intermediate in many synthetic routes, making it a staple for those looking to introduce a 2-bromoethyl fragment onto polycyclic aromatic cores. Laboratory recipes may look simple in print, but once scaled up, the real-world details emerge—impurity profiles, reproducibility, control over side-reactions, and ease of purification. Each physical property of 1-(2-Bromoethyl)Naphthalene—its melting point, color, odor, crystallization habits—offers telltale signals about process consistency, which can be lost on those handling only a handful of grams versus someone running multi-kilogram batches.

    Our production consistently reaches a purity of 98% or higher, with strict control of moisture and residual halides. During isolation and quality checks, trained eyes focus not just on purity, but on slight shifts in every chromatogram that suggest deeper issues lurking upstream. That vigilance saves countless hours for downstream users who want clean transformations and predictable yields. A difference of even a fraction of a percent in impurity content becomes critical in pharma and advanced materials. Smaller traders and repackers rarely see how trace byproducts can snowball, causing headaches for those running late-stage synthesis or chasing regulatory compliance.

    Understanding Its Place in Synthesis

    Those who work with halogenated naphthalenes know their value in creating novel drug candidates, organic electronic devices, and specialty dyes. 1-(2-Bromoethyl)Naphthalene often serves as an alkylating agent, providing a simple pathway to introduce naphthyl moieties into more complicated organic frameworks. This route enables the formation of carbon–carbon and carbon–heteroatom bonds—targets prized in both medicinal and materials chemistry.

    For researchers designing a new antagonist or exploring photonic polymers, the ability to source the same product with tightly controlled specifications directly from a manufacturer makes the difference between stalled projects and rapid progress. Several customers mention how the color of a crude batch, or the solvent retained during isolation, can alter kinetics and yields. Through direct manufacturing, we adjust crystallization and drying parameters to bring a product that meets application-specific needs—whether a project demands strictly colorless solid or flexibility in solvent compatibility.

    Going Beyond Specifications

    Reliability grows from continuous hands-on assessment. Every kilogram produced tells a story about the reactor conditions, workers' vigilance, and the learning curve traced over previous campaigns. In our facility, we maintain extensive documentation and process logs. Operators and quality control chemists discuss not just numbers, but trends—how unexpected ambient humidity during crystallization can affect purity, or how micro-batch tests can pre-empt large-scale surprises. Manufacturing isn’t limited to chemistry; it’s the blend of judgment, attention, and humble willingness to improve with each run.

    Not all sources approach last-step purification with the same purpose. Outsourced resellers may consolidate multiple suppliers, often introducing risk for unknown contaminants, batch inconsistencies, and vague traceability. On the contrary, operating our own reactors means every lot shipped comes with documented history. That transparency builds confidence, particularly for users mandated to report full origin and processing details for regulatory audits.

    Meeting the Needs of Complex Markets

    Supplying researchers in different sectors has shown us that demands can change quickly. In organic synthesis, the pressure lies on functional group integrity; a missed spot test, or an ambiguous IR band, signals trouble. Electronic applications push other aspects, such as the exclusion of metal contaminants or fluorescent byproducts. Pharmaceutical R&D teams care deeply about even minor trace byproducts and the solvent history that might trip up biological assays.

    Our facility’s layout—dedicated reactors, high-vacuum distillation lines, and closed transfer systems—falls in line with those needs. Every new campaign brings a round of review and adjustment, because short-term cost savings pale next to the price of a recall or a failed trial. We keep redundant quality checks throughout, not just at release. The ability to respond rapidly to custom purity thresholds—such as requesting halide content below parts per million, or no detectable aldehydes—builds long-term trust with customers who share these data downstream.

    Differentiating What Direct Manufacturing Provides

    Quality control and a firm awareness of customer feedback play a stronger role than any technical brochure suggests. Feedback from researchers using 1-(2-Bromoethyl)Naphthalene in asymmetric synthesis or new material platforms often points to a chain of minor adjustments—in solvent ratios, cooling protocols, or recrystallization temps—that manufacturers implement, but third-party sellers cannot. That adaptive loop creates products that function under real-world laboratory and pilot plant conditions.

    Some newcomers to the field might think impurities at trace levels do not affect larger synthesis. Anyone who has scaled up a reaction knows how skipped filtration or insufficient drying in the intermediate steps can sabotage subsequent yields. Our engineering and analytic teams work together to confirm not just initial purity, but the thermal stability and handling characteristics carried through to customer operations. That detailed attention prevents unplanned shutdowns or unusable reserve stock. No shortcut compensates for robust hands-on control.

    Through incremental improvements in process consistency, we reduce the variables our partners have to manage. In practice, that means fewer surprises, more repeatability, and safer scalability. The experience of running the same product in large volumes offers insights into optimal storage temperatures, shipping stability under variable climates, and which packaging materials help maintain product integrity during international delivery. These operational refinements do not always reach the sales pitch, but in R&D and production, they prove key over long timeframes.

    Why Direct Traceability Matters

    Today’s regulatory environment requires more than a basic certificate of analysis. Research on naphthalene derivatives is subject to growing scrutiny, emphasizing traceability from synthesis through final use. For regulatory filings—pharmaceutical submissions, environmental permits, and industrial audits—users often request full batch histories, method of manufacture, and specifics about starting materials.

    Our records support this. Processes get audited for compliance with local and international standards, from environmental protection requirements to good manufacturing practice recommendations. Direct manufacturing enables ready access to supporting documentation—reaction conditions, batch numbers, even raw material supply chains—reducing turnaround time for complex projects.

    End-users working on sensitive projects trust the clarity offered by vertically integrated production. Third-party handlers sometimes obscure the path a product has traveled, which complicates root-cause analysis if downstream issues arise. We track everything from batch labeling to equipment cleaning logs. If someone years later questions a particular impurity or an anomalous test result, our files cover the reasoning and process changes adopted then. Transparency is integral, not an afterthought.

    Responding to Research-Driven Demands

    Direct interaction with researchers sharpens priorities. Feedback about new instrumental approaches or unexpected reaction side-products triggers process tweaks—changing distillation rates, adjusting crystallization solvents, or adding analytical standards. These are solutions traders rarely provide, because they have no say in upstream processing. In contrast, every inquiry or concern feeds into our next production run.

    In medicinal chemistry, time lost due to non-reproducible building blocks is painful. Reliable 1-(2-Bromoethyl)Naphthalene enables scale-up, parallel synthesis, and IP filings without pause for purity retesting. Several customers have identified downstream savings of weeks per project when intermediate quality issues do not sideline screening efforts. Iterative improvements—adding a gas purge or swapping out filtration aids—hatched through direct manufacturing save months in project cycles.

    Handling Scale and Customization

    Batch production lets us respond flexibly. From gram-scale research orders to multi-kilo industrial runs, we adapt packaging, logistics, and purity to fit each application. Constraints from handling restrictions, shipping rules, and customer-specific storage needs require hands-on coordination. There’s no substitute for knowing how the product travels: how a rough ride or a customs delay might affect stability, or how to package to prevent light or moisture incursion.

    Some end uses require custom blends or added stabilizers. Others focus on minimizing waste in synthesis, so we look for routes that boost atom economy, decrease byproduct volume, or improve conversion rates. Each feedback cycle sheds light on overlooked details, from dissolution rate in non-polar solvents to shrink-wrap failures or cap leakage during long-haul shipping. Adjustments follow real outcomes, not guesses or generic advice.

    Scaling up to industrial volume brings its own lessons. Temperature profiles that work at flask scale can react differently in jacketed reactors. Even heat distribution, agitation speed, and cooling capacity affect purity and byproduct profile. We document each change, integrate feedback, and communicate the results back to users aiming for reproducibility at their end. Technical support means more than phone calls; it means understanding the why and how behind every suggested tweak.

    Sustainability and Responsible Manufacturing

    As the chemical industry moves toward greener practices, sustainability isn’t a buzzword on the workshop floor. Chemical manufacturers see its very real challenges and opportunities in selecting raw materials, minimizing waste, and designing safer, more efficient reactions. With 1-(2-Bromoethyl)Naphthalene, attention extends to solvent recycling, closed waste streams, and careful selection of brominating agents to limit environmental hazard.

    Customers are becoming more attuned to regulatory footprints, waste management, and EHS compliance for all intermediates in their pipeline. This drives continuous upgrades to process design and safety features, and it influences the raw materials suppliers we work with. For some applications, solvent-free or water-assisted protocols matter. For others, ensuring clean air emissions and safe handling for our teams takes the lead.

    Incremental improvements in waste minimization and yield efficiency add up: less bromoalkane loss, reduced off-spec disposal, lower energy input per ton produced. Those historical lessons, learned from actual bench and plant experience, feed future decision-making rather than floating as distant targets. Our teams hold regular debriefs after every campaign, looking for opportunities to reduce losses and boost sustainability, without sacrificing purity or reliability.

    Lessons Built Over Years

    Manufacturing 1-(2-Bromoethyl)Naphthalene isn’t a plug-and-play operation. Each step builds on hard-won insight—about batch-to-batch crystallization differences, on how a minor tweak in the work-up can lower future rejection rates, or about how changing one raw material shifts the whole downstream profile. As regulations tighten and research applications grow, these lessons become more important, not less.

    Most of these nuances only become clear through direct manufacturing. Resellers and brokers bring their own pressures—pushing for volume, quick turnaround, and uniformity above all else—but lack direct control over where things go wrong or right. In contrast, our operators talk to the chemists developing new catalysts, the engineers running new reactors, and the quality managers vetting incoming raw materials for each campaign. That experience, and the trust it cultivates, forms the core difference seen at every stage.

    Looking to Future Demands

    As applications broaden, demand for better-controlled intermediates like 1-(2-Bromoethyl)Naphthalene grows. Emerging fields—OLEDs, next-gen materials, and biologically inspired compounds—require ever tighter purity profiles and documentation trails. Meeting these needs draws on more than basic process chemistry. It calls for investment in infrastructure, training each worker to watch for early warnings, and constant adjustment of facility operations.

    We know that every step, from bromination to isolation, can tip the balance between success and setback for our partners. Their feedback continually guides us toward better solutions, sometimes in response to hurdles nobody could foresee at the outset. This gives purpose to the extra hours spent troubleshooting, documenting, and revisiting failed trials until the product meets the exacting standards expected from direct manufacturers.

    Continued Commitment

    Direct manufacturing fosters accountability. From sourcing and scaling through problem-solving and support, knowledge grows deeper with every production cycle. As regulatory, technical, and market pressures increase, those who know the intricacies of producing and delivering 1-(2-Bromoethyl)Naphthalene remain the most adaptable and trustworthy partners in the field.

    The journey from raw material to finished product weaves experience, continuous learning, and close collaboration with those who build today’s and tomorrow’s chemistry. Every batch produced, checked, and delivered represents more than a transaction—it stands for ongoing commitment to quality, reliability, and the ever-advancing needs of research and industry.