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1,1,2-Trichloro-2,3,3-Trifluorocyclobutane

    • Product Name 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane
    • Alias HCFC-2313
    • Einecs 221-057-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    162610

    Chemical Name 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane
    Molecular Formula C4Cl3F3
    Molecular Weight 229.40 g/mol
    Cas Number 356-17-4
    Appearance Colorless liquid
    Boiling Point 116°C
    Melting Point -35°C
    Density 1.608 g/cm³
    Refractive Index 1.422
    Solubility In Water Insoluble
    Flash Point 19°C
    Vapor Pressure 44 mmHg (20°C)

    As an accredited 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging is a 500 mL amber glass bottle with a secure cap, labeled “1,1,2-Trichloro-2,3,3-Trifluorocyclobutane.”
    Shipping 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane should be shipped in tightly sealed containers, clearly labeled, and compliant with relevant hazardous material transport regulations (e.g., DOT, IATA, IMDG). Store in a cool, well-ventilated area, away from incompatible substances. Use protective packaging to prevent leaks or spills during transit, and include proper safety documentation.
    Storage Store **1,1,2-Trichloro-2,3,3-Trifluorocyclobutane** in a tightly sealed container within a cool, dry, well-ventilated area, away from direct sunlight and incompatible materials such as strong oxidizers. Ensure appropriate chemical labeling and access to spill containment equipment. Avoid sources of ignition, moisture, and extreme temperatures. Use secondary containment to prevent leaks and handle only with proper personal protective equipment.
    Application of 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane

    Applications of 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane in Industrial Manufacturing

    As a specialized manufacturer of 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane, we supply this critical intermediate to select downstream industries where its unique halogenated structure enables challenging chemical transformations. The following segments represent established and high-purity application routes, supported by verified customer production operations worldwide.

    1. Advanced Agrochemical Synthesis

    Producers of high-activity crop protection agents utilize our material as a key halogenated intermediate for the synthesis of triazine and pyridine-based herbicides. The introduction of chlorine and fluorine into the cyclobutane backbone aids target specificity in final molecules. The raw material undergoes nucleophilic substitution, providing a functionalized scaffold for subsequent coupling and ring-opening steps. Careful control of addition timing and molar ratio guides yield and byproduct formation according to strict environmental and residue standards.

    Industry compliance standards

    • FAO/WHO specifications for pesticide technical materials
    • ISO 9001:2015 Quality Management Systems
    • REACH registration requirements for specialty organofluorine intermediates
    • US EPA Registration 40 CFR Part 152 (for active ingredient derivatization)

    Typical usage ratio

    • In herbicide intermediate manufacturing, 2–7% by weight in the initial halogenation charge, with adjustment based on desired active moiety substitution and batch size, typically controlled by in-process HPLC assay.

    Downstream process integration

    • Dosed directly in the cycloaddition or halogen-exchange stage of active ingredient synthesis, with reaction temperatures maintained between 80–130°C to achieve complete conversion, followed by distillation or solvent extraction as dictated by downstream purity requirements.

    Final product types

    • Selective herbicides targeting resistant grass weeds
    • Pre-emergence soil-applied pesticides
    • Technical-grade agrochemical key intermediates

    2. Fluorinated Refrigerant Precursor Manufacturing

    Major refrigerant and specialty gas producers use this compound in multi-step halogen-exchange and dehydrohalogenation sequences to generate next-generation refrigerant molecules like HFOs and HCFOs with low global warming potential (GWP). The raw material’s structure provides a balance of volatility and reactivity optimal for selective catalytic processing, critical for both industrial-scale throughput and compliance with phase-down regulations globally.

    Industry compliance standards

    • ASHRAE Standard 34: Designation and Safety Classification for Refrigerants
    • EU F-Gas Regulation (EU) No 517/2014 (2026 update compliance)
    • ISO 14001:2015 Environmental Management Systems
    • Japan JIS K 2211 Fluorocarbon Quality Standards

    Typical usage ratio

    • Utilized at 5–14% of the total reactant charge, with ratio set according to final molecular structure pathway and desired fluorine incorporation, adjusted via real-time GCMS endpoint monitoring.

    Downstream process integration

    • Fed in continuous or batch reactors at the initial halogen-exchange stage, with subsequent in-line distillation and HF-alkali neutralization, ensuring product GWP and static pressure fall within international refrigerant standards.

    Final product types

    • Next-generation HFO (hydrofluoroolefin) refrigerants
    • HCFOs (hydrochlorofluoroolefins) for automotive and industrial AC systems
    • Technical-grade refrigerant gases meeting GWP benchmarks

    3. Specialty Polymer Monomer Production

    Manufacturers of fluorinated and chlorinated specialty polymers employ this material as a cyclobutane-derived monomer for copolymerization. The structure imparts beneficial properties such as chemical resistance, flame retardancy, and dielectric stability to the resulting polymers. The raw material is introduced post-purification to minimize impurities that can affect copolymer chain length and mechanical properties. Polymerization conditions and monomer ratios are calibrated precisely to guarantee functional end-use performance and regulatory conformance.

    Industry compliance standards

    • UL 94 Flammability Standard for Polymer Materials
    • RoHS Directive 2011/65/EU Annex II
    • ISO 9001:2015 for polymer resin production
    • ASTM D638 (Tensile Properties of Plastics)

    Typical usage ratio

    • In specialty copolymer synthesis, typically 0.8–3.2% by total monomer weight, modulated to achieve specific chlorine and fluorine content as per finished product requirement sheets.

    Downstream process integration

    • Incorporated following base monomer purification, introduced in a solvent (commonly aromatic hydrocarbon) by metered addition into the polymerization reactor, with process parameters tightly monitored for exotherm control and chain propagation efficiency.

    Final product types

    • Flame-retardant wire and cable insulation compounds
    • High-performance fluoropolymers for chemical process linings
    • Functional specialty films used in electronics

    4. Organic Electronic Chemical Synthesis (OLED/Display)

    Producers of OLEDs and advanced organic electronic materials leverage this specialty cyclobutane derivative in multi-step syntheses for integration into selective charge-transport and protection layers. Its halogenation pattern facilitates attachment of aryl and alkyl substituents while improving resistance to UV and oxidative degradation in the final device stack. Stringent purification and batch homogeneity standards guide raw material usage across the chain from organic laboratory scale-up to full production lines.

    Industry compliance standards

    • JEITA EIAJ CP-0701 Compliant Purity Standards for OLED Precursor Chemicals
    • ISO 14644 Cleanroom Standards for Electronic Materials
    • IEC 61249-2-21 for Halogen Content in Printed Circuit Substrates
    • GMP for Electronics (as specified by IEST-TM-CC1246D)

    Typical usage ratio

    • 0.2–1.5% of total molecular weight in OLED charge-transport layers, adjusted based on thickness requirements and device emission parameters determined during pilot coating tests.

    Downstream process integration

    • Added at the precursor synthesis stage for electronic chemicals, dissolved in high-purity solvents, then subjected to multi-step synthesis, chromatographic purification, and post-synthesis impurity fingerprinting before device integration.

    Final product types

    • OLED emissive and transport layers for smartphone and television displays
    • Thin-film transistor protective coatings
    • Halogenated small molecules for light-emitting and display panels
    Free Quote

    Competitive 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    1,1,2-Trichloro-2,3,3-Trifluorocyclobutane: Purpose-Driven Chemistry from the Source

    Manufacturing specialty cyclobutane derivatives demands precision, patience, and genuine know-how. Our experience with 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane has shown the field rewards hands-on work backed by rigorous traceability and quality controls. Our facility developed processes over years of research and industrial practice. Every batch shows traces of this path: subtle differences in density, refractive index, moisture content, and by-products. No two runs look exactly the same unless tightly managed. Reliable sourcing from the manufacturer cuts down on these fluctuations, making downstream applications steadier and less prone to unwanted surprises.

    Key Product Details: Purity Crafted on the Line

    This material lands on the desks of companies and research teams facing real-world technical challenges. The model and production grade we offer (99% minimum purity by GC) stem from methods designed for large-volume fluorinated and chlorinated intermediates. Properties like colorless appearance, specific gravity, and stability under common process conditions reflect intentional design in our production. Such details make fluid handling on your line less of a guessing game. Our monitoring for trace impurities and moisture content comes from a long-standing focus on safety and reaction specificity. Excess moisture and unknown contaminants can turn a batch into a costly liability, so our process addresses these sources head-on.

    Handling needs for this compound also inspire smarter packaging design—glass-lined steel drums, proper seals, and transport solutions meant for sensitive goods. The benefits land not only with major chemical synthesis plants but also with niche users in advanced research. Requests often focus not only on volume but on critical purity thresholds or analytical reports confirming key attributes. Meeting these standards means investment into our own laboratory infrastructure, so we can stand behind documented lot-to-lot consistency. Third-party lab results are welcomed, but manufacturers that back up their own QA add a needed layer of reliability you just don’t find further down the chain.

    The Use Case Picture: What 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane Really Does

    Years in this industry have proven that most requests for this molecule center on its role as a versatile intermediate. Think agrochemicals, specialty fluoropolymer feeds, and sometimes halogenated refrigerant study—these are common destinations. We’ve heard some clients talk about using it in pilot-scale routes towards new insecticide active ingredients, others mention halogen exchange reactions or fine-tuning physical properties in new elastomer lines. The structure—its three chlorines and three fluorines on a cyclobutane backbone—allow for selective stepwise transformation paths. Our tech teams have collaborated directly with client-side chemists to optimize reaction sequences involving this compound. Sharing spectral data, confirming removal of by-products, or even tweaking delivery containers for rare solvent compatibility requests: this is where it pays to work with manufacturers, not resellers.

    Usage techniques run the spectrum. Some processes run at elevated pressures and temperatures, demanding assurance that the supplied material won’t undergo side reactions before the controlled step. Others want material in inert atmospheres or proprietary solvent blends. You’d be surprised by the feedback from process engineers who finally swapped an undefined raw material for one consistent source. Time lost on revalidation, fault tracing, and incomplete conversions drops sharply. Many overlook how handling and small-batch synthesis amplify issues that seem trivial at pilot scale, but add up to real dollars and downtime in bulk runs.

    How This Compound Stacks Up

    People often ask how 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane stands out compared with other chlorofluorinated cyclobutanes or standard trichlorofluorinated options. It boils down to a few fundamentals: reactivity profile, selectivity, and safety under the intended use conditions. Years comparing different halogenated cyclobutanes on our preparative lines have taught us that position and number of halogen atoms change the game in both reactivity and downstream compatibility. In some reactions, a trifluorocyclobutane with fewer chlorines resists unwanted eliminations better—at the cost of less versatility for certain nucleophilic substitutions. Conversely, heavily chlorinated compounds might demand different stabilization but open unique possibilities as cross-coupling partners. Fine control of side groups defines what’s feasible at industrial scale.

    From real feedback, personal visits to installations, and troubleshooting together, we’ve seen clear patterns. For instance, this compound’s boiling point, vapor pressure, and compatibility in halogen-exchange chemistry set it apart from both monofluorinated and perfluorinated rings. Control of side products in downstream synthesis is routine rather than a headache. Customers using related analogs told us about buildup of hard-to-remove byproducts, corrosion issues, and unplanned shutdowns—problems that our controlled cyclobutane builds tend to avoid. No speculative “may suit your process” claims. Instead, look at field data and historical run records. Our ongoing relationships with end-users create feedback loops that result in real product improvement.

    Safety and Environmental Considerations: Real-World Accountability

    Inhalation, contact, and improper handling of all chlorofluorinated cyclobutanes present definable risks. Few talk openly about the messy side of the business, but the test of any production shop comes down to documented handling procedures and an honest review of incident history. Safety protocols started on our floor often spark better practice elsewhere. For example, emergency venting systems, real-time air monitoring, and sealed transfer lines grew from actual accident reports—not just regulation boxes to tick. Regular operator briefings and live-response drills became part of our plant culture after one minor exposure led to significant downtime.

    Solvent compatibility, reactive storage material, and ongoing waste stream management shouldn’t come as afterthoughts. Compounds like this one degrade under UV or in highly basic or acidic environments; our infrastructure includes closed systems and secondary containment. Scrubbing emissions, periodic inspection of gaskets and hoses, and redundant filtration units spring directly from on-site lessons learned during routine downtimes. Documenting process incidents creates real improvements, and transparency with customers on these issues leads to trust beyond the sales pitch. Working directly with end-users, we’ve sometimes designed joint-site visits to review safe unloading, storage, and small-scale transfer practice in detail.

    Post-process effluent remains an area of focus worldwide, especially for halogenated organics. Our waste treatment staff use advanced incineration and chemical destruction lines; we maintain records open for inspection. Environmental compliance can’t be glossed over. We collaborate with accredited labs to monitor trace halogen residuals in discharged water and air, and we’re part of shared industry research groups working to innovate greener by-product disposal. Smaller users often benefit from our guidance navigating evolving regulatory standards, particularly in export markets where differences in reporting and compliance surprise even seasoned procurement teams. Our investment in safe handling infrastructure aligns with evolving ESG expectations in both developed and emerging markets.

    From Lab to Line: Why Manufacturer Direct Makes a Difference

    In the real world, unreliable supply lines and inconsistent grades can wreck confidence in a multi-step synthesis. We’ve watched partners grapple with cost overruns from batch-to-batch variation in small pilot batches sourced from resellers. Material made at scale from trained operators using consistently sourced raw feedstocks wins out in predictable performance. Consistency comes from controlled temperature programming, monitored reagent feeds, and deep experience handling the quirks of large-volume halogenation. We track each run with a full certificate of analysis, and invite customer audits for key grades. Our teams aren’t separated from the product—they’re often on the line, dealing with equipment upgrades, maintenance issues, and the myriad details that guarantee downstream reliability.

    End-users working in emerging material development value quick response on product variation, technical questions, and risk mitigation. We field these daily—about how oxidation state impacts reaction, why trace contaminants inhibit catalysts, or how we maintain sub-ppm water levels in humid months. Our technical support teams receive direct process feedback from factories and labs, not filtered through trading brokers. Even small volume buyers get access to the same technical backbone backing our major customers. Key partnerships form over this kind of detail-oriented support. Working directly with manufacturers builds a cycle of improvement, flagging minor production issues that traders overlook until major run failures happen. Years spent troubleshooting together fosters mutual understanding beyond transactional interactions.

    Transparency extends into traceability. Each product batch carries records tracing feedstock origin, reaction logs, purification steps, and chain-of-custody documentation. This isn’t a bureaucratic checkbox—it is the backbone of product identity. Manufacturers used to hearing “just get me the best price” change their tune when faced with a recall, liability event, or certification audit. We’ve guided firms through voluntary traceability checks, reviewed documents together for customs authorities, and helped small business clients satisfy downstream regulatory requests. These are real moments, not just abstract stories, and each has driven improvement in our own reporting and archiving standards.

    Innovation, Feedback, and the Future of Organofluorine Chemistry

    Innovating in chlorofluorinated intermediates never finished at the product design stage. Advances in analytical instrumentation, user safety protocols, and green manufacturing practices now blend with longstanding technical formulas. Our product managers collect customer feedback, track performance data from independent panel tests, and work with research partnerships targeting new application areas. Some client firms test new catalysts or polymerization approaches; others experiment with alternate cyclobutane building blocks. We support pilot runs, review real process data, and compare outcomes with reference syntheses published in the public domain. Placing our own staff at the interface accelerates the innovation pipeline—both sides see benefit in project agility and honest feedback on what works and what falls short.

    Real change often starts with a customer request we’ve never seen before. Maybe a research group needs an ultra-dry batch with extended analytical documentation for an export trial, or a production client asks for bulk delivery solutions that minimize transfer losses. Our feedback collection channels prompt tweaks in manufacturing or post-processing. One example was a midstream customer struggling with trace metallic residue affecting catalytic conversion rates; together, we redesigned reactor internals and tightened wash protocols, yielding demonstrably cleaner product and improved final yield. Many industry units stop learning from the field at the point of sale. We keep that door open, and over time, it creates a smarter, more responsive production environment benefiting all partners in the value chain.

    Product Differentiation in the Language of the Line

    This compound’s standout features come into sharper relief the deeper one gets into hands-on chemistry. Competing fluoro- or chloro-cyclobutanes sometimes carry similar nomenclature, but actual process behavior often surprises newcomers. We learned from customer process notes and our own batch records that subtle shifts in isomer content, residual acidity, or halide dispersity make concrete downstream differences. The specifications often cited by catalog suppliers don’t cover the reality of live chemistry, where product-on-paper diverges from product-in-tank. Our QA departments run parallel tests using both classical wet chemistry and modern chromatographic and spectrometric techniques, rooting out batch inconsistencies hiding under bulk certifications. Without this level of control, marginal differences turn into real performance hurdles down the line.

    Handling, transport, and storage present unique challenges for halogenated cyclobutanes. Temperature swings, unforeseen exposure to incompatible materials, or prolonged storage in sub-optimal containers lead to diminished yields, color changes, or increased hazard potential. We invest in specialized containers, real-time datalogging, and rapid-response replacement for compromised shipments. Even the seemingly minor details matter: end-users comment positively on our drum lining choices, blend compatibility, and robust stoppers—all responding to issues encountered with generic commercial packaging. Site visits from our logistics and QA staff help document best practices and feedback to our plant operations for the next round of improvement.

    Supporting Next-Generation Technologies

    Customers increasingly use our 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane as a feedstock in high-performance elastomers, advanced agrochemicals, and experimental refrigerant pathways. Each emerging use case stretches demands on purity, documentation, handling, and collaborative troubleshooting. Academic clients pursue complex synthetic targets that stress every variable—batch consistencies, impurity profiles, and spectral fingerprinting. We’ve answered detailed queries for process validation, co-documented multi-step synthetic sequences, and shipped stabilized micro-lots for laboratory development. Our goal is not to sell a one-off product, but to partner with forward-thinking teams to push the boundaries of what these molecules can do.

    We follow technical trends across application fields—sustainable chemistry initiatives, circular economy strategies, and advanced analytical method development. New regulatory frameworks put greater pressure on full lifecycle transparency. We listen to customer questions, proactively pursue new analytical protocols, and iterate manufacturing steps to both anticipate and adapt to next-generation regulatory, technical, and market requirements. The field will keep evolving, and so will the role this and related compounds play.

    Long-Term Focus: Ethical, Technical, and Operational Responsibility

    No manufacturer gets everything right on day one. The reality of chemical manufacturing—especially when balancing safety, performance, and compliance goals—demands a willingness to confront challenges transparently. Our experience being held accountable by customers, regulators, and internal teams has shaped not only how we approach this product, but company culture overall. Each audit, each process review, and every incident closeout brings lessons feeding directly back into safer, more consistent, and future-ready operating procedures.

    We strive to raise the industry bar in traceability, lot documentation, and forward-facing analytics, driving not only our compliance but that of our partners up the supply chain. Our integrated support and R&D approach bridge the gap between technical development and daily operations—built on a foundation of real-world experience and open dialogue with users. True expertise forms not just by knowing what’s in the bottle, but by living alongside users, learning from their successes and mistakes, and striving for ongoing mutual improvement.

    As use cases for 1,1,2-Trichloro-2,3,3-Trifluorocyclobutane expand and technical standards tighten, direct partnership with the source remains the surest way to maintain performance, reliability, and compliance in the face of change. Our processes, support teams, and ongoing product development offer users of this specialty chemical the steady foundation needed for success—no matter how quickly the industry landscape shifts.