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HS Code |
359494 |
| Cas Number | 75-50-3 |
| Chemical Formula | C3H9N |
| Molar Mass | 59.11 g/mol |
| Appearance | Colorless gas |
| Odor | Fishy, ammonia-like |
| Boiling Point | 2.9°C |
| Melting Point | -117°C |
| Density | 0.668 g/cm3 (at 25°C, liquid) |
| Solubility In Water | Very soluble |
| Vapor Pressure | 1,940 mmHg (at 20°C) |
As an accredited Trimethylamine [Anhydrous] factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Trimethylamine [Anhydrous], 500 mL, is packaged in a sealed, high-pressure steel cylinder with proper labeling and safety warnings. |
| Shipping | Trimethylamine [Anhydrous] requires shipping in tightly sealed, corrosion-resistant cylinders under inert gas. It is a highly flammable, toxic compressed gas and must be handled as a hazardous material, in accordance with DOT regulations. Shipping labels must indicate UN1083, hazard class 2.1 (flammable gas), and appropriate emergency procedures must be followed. |
| Storage | Trimethylamine [Anhydrous] should be stored in tightly closed, corrosion-resistant containers in a cool, dry, and well-ventilated area. Store away from sources of heat, sparks, or open flames, and protect from moisture. Segregate from acids, oxidizers, and halogenated compounds. Ensure containers are clearly labeled, with proper grounding and bonding during transfer to prevent static discharge. Use appropriate gas cabinets if in compressed form. |
Applications of Trimethylamine [Anhydrous] in Industrial ManufacturingTrimethylamine [Anhydrous] serves as a key intermediate across several industrial sectors where its chemical reactivity and purity impact product quality at scale. We supply high-grade material to original manufacturers, ensuring consistency and compliance through every transport and handling stage. 1. Choline Chloride Production for Animal NutritionMajor feed mills incorporate our trimethylamine [anhydrous] directly into the synthesis of choline chloride, a critical vitamin for poultry and livestock health. The material reacts with ethylene oxide or hydrochloric acid in batch or continuous reactors, depending on scale. Strict process control maintains purity and prevents secondary amine formation. Choline chloride quality depends on the trimethylamine assay and low moisture specification, demanding reliable raw input and close adherence to animal feed safety guidelines. Our QC protocols align strictly with end users’ GMP animal feed plants. Industry compliance standards
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2. Quaternary Ammonium Compound Synthesis (Disinfectants & Antistatics)Formulators within the specialty chemicals sector use trimethylamine as a primary alkylation agent when manufacturing quaternary ammonium salts. It reacts with various alkylating agents to produce quats used in hard surface disinfection and textile processing. The end point calculation and reactivity depend on the length and type of alkyl group introduced. Process equipment requires explosion-proof handling and continuous gas monitoring for safety. Downstream product quality relies on stringent control of byproduct amines and residual alkylating agents, with real-time QC matching the needs of end-user certification requirements. Industry compliance standards
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3. Pharmaceutical API Synthesis (Local Anesthetics and Bronchodilators)Pharma API producers utilize trimethylamine as a key alkylation or neutralization agent in the production of active pharmaceutical ingredients such as lidocaine and theophylline derivatives. Precise measurement and feeding in closed systems protect batch integrity and prevent contamination. We ensure pharmaceutical-grade material that meets low amine impurity and residual water specifications. Each batch ships with detailed COA and traceability to raw material lots. Process reproducibility and regulatory acceptance depend on strict feedstock quality. Industry compliance standards
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4. Ion-Exchange Resin ManufacturingResin producers apply trimethylamine during the functionalization of polystyrene/divinylbenzene beads to develop strong base anion resins. The amine acts as a quaternizing agent, forming trimethylammonium functional groups on the bead matrix. Strict process control keeps particle size distribution and free base levels within exchange capacity specs. We guarantee uninterrupted supply with low water content, as absorption between process steps leads to off-spec moisture pickup in resin beads. Industry compliance standards
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5. Acrylate Catalyst and Solvent ProductionAcrylate producers require trimethylamine for the synthesis of trialkylamine catalysts and low-boiling solvents used in polymerization and coatings manufacturing. The material’s consistent vapor pressure and low impurity content are essential for continuous catalyst blending operations and in-situ neutralization steps. Close control of gas feed and purge cycles keeps catalyst lines free from residues or blockages. Industry compliance standards
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6. Agricultural Fumigant Precursor ManufacturingAgrochemical suppliers use trimethylamine in the synthesis of fumigant intermediates, for instance, in the creation of methyl bromide alternatives and stabilizers for chloropicrin mixtures. The process demands careful handling with dedicated pressure-rated vessels and gas leakage monitoring. Product purity and traceability, along with exact stoichiometry, directly impact the finished fumigant performance and field reactivity. We supply stabilized amine for direct transfer to agrochemical plants under sealed logistics. Industry compliance standards
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7. Rubber Accelerators and Vulcanization AgentsRubber chemical manufacturers select trimethylamine to neutralize acids and catalyze the formation of accelerator salts such as tetramethylthiuram disulfide (TMTD) and related thiazole accelerators. The input quality of the amine directly affects curing kinetics and safety profiles of end products. Operators require prompt deliveries and minimal amine residue to meet demanding commercial tire, hose, and industrial rubber production schedules. We support customer plant audits to verify consistent raw material supply. Industry compliance standards
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Speaking from decades of experience in synthesizing amines at industrial scale, trimethylamine [anhydrous] remains one of the cornerstones in our product lineup. As chemists and plant operators, we know the challenges this molecule brings—from its pungency, flammability, and volatility, to the rigorous purity demands in downstream applications. Our trimethylamine [anhydrous], characterized by purity at or above 99.9%, comes bottled under pressure, clear and colorless, strictly controlled for residual water, and adheres to the specifications trusted by leading pharmaceuticals, agrochemicals, and polymer producers.
For many partners in the chemical supply chain, trimethylamine’s utility covers a wide spectrum. It functions as a methylating agent, an intermediate for quaternary ammonium compounds, choline chloride, ion-exchange resins, and many specialty chemicals. Its selection in synthesis isn’t based on convenience—accuracy in purity, moisture content, and packaging integrity decide the batch yield and downstream product safety. Some competitors settle for solution-grade trimethylamine to simplify handling or lower price, but this ignores the extra work required in drying and the risk of side reactions from hydrolysis or unwanted water content. We supply it anhydrous because moisture interferes in too many synthetic routes.
Our manufacturing process does not cut corners by blending lower-purity grades or by relying on bulk dilution. We base our output on continuous reaction and precise fractional distillation, followed by state-of-the-art moisture scrubbing and multi-stage filtration. Pressure-rated storage vessels and isotank logistics play big roles in keeping trace water and oxygen out. From raw dimethylamine and methanol to the finished bottled gas, at no stage do we accept batch shortcuts or undocumented additions. Decades of refinement in this operation have taught us the importance of instrument calibration and batch record integrity—a slightly misplaced valve or gasket can introduce enough contamination to throw off a whole reactor’s output.
Most users will be aware that trimethylamine boils at just over 3°C, putting it firmly in the realm of low-boiling, high-pressure gases at ambient conditions. We provide our product compressed to maintain it in liquid phase, delivered with accurate fill weights and safety-vented cylinders. Every filling is accompanied by both gas-phase and liquid-phase GC analyses, as analytical surprises at the customer’s site can completely halt a batch in progress. In plant-level work, nothing substitutes for traceability—being able to trace any anomaly back to specific valve swings, cylinder pre-purges, or batch records allows us to minimize disruption and support our partners when the unexpected occurs.
Many manufacturers offer trimethylamine in aqueous solution, typically at 25–40 percent for use where solvent-compatibility isn’t critical. That’s fine for some sectors—water-phase reactions, less-precise chemical syntheses, or cleanup operations. In our own early days, we supplied both solution and gas-phase grades, but feedback from advanced polymer and agrochemical customers led us to focus on the highest anhydrous purity. Dry trimethylamine eliminates concerns about unwanted quenching or lower product yields caused by unintentional water.
Some might see technical-grade trimethylamine as sufficient for most jobs, but in our experience, the difference shows up fast in applications like polymerization catalysts, where even minor contaminants can poison metal centers, affect molecular weights, or impair optical clarity in end products. A fine amine that carries over trace by-products or residual water invites costly troubleshooting and process hold-ups. Our anhydrous product avoids these pitfalls, supporting processes that rely on strict control over every atom entering the reactor.
We have supplied trimethylamine [anhydrous] for decades to customers ranging from large multinational plants to niche specialty labs, so we see firsthand where this material proves indispensable. In agriculture, it’s a fundamental building block for herbicides and fungicides like paraquat and diquat. The quaternization reactions behind these crop protection agents require an amine stream free of unsaturated or oxidized residues. Trimethylamine’s role in these reactions is often overlooked but absolutely critical—if a batch absorbs moisture in transit, whole syntheses can underperform or fail QA inspections, which we have seen too many times with substandard shipments from less-experienced sources.
For pharmaceutical intermediates and active ingredients, anhydrous quality reduces risk and boosts consistency in high-value products. Many labs and process engineers report improved reproducibility and product purity when switching to our material. In personal interviews with our technical team, pharmaceutical manufacturers often express frustration with solution-based amine deliveries—variability in water content leads to extra drying steps or unpredictable salt formation. It’s no exaggeration to say the reliability of an entire batch can hinge on controlling every variable, including something as deceptively simple as the water content of a methylating agent.
The demand rises in electronics and energy sectors, too. Trimethylamine [anhydrous] contributes to ion-exchange resins and antistatic agents for printed circuit board production. Inferior grades containing even minor impurities—such as other amines, aldehydes, or excess water—can throw off the performance of an entire resin batch or cause electrical failures in delicate circuitry. We maintain our purification sequence to ensure that every kilogram meets the critical standards of these sectors, as electronics clients are particularly sensitive to trace contamination.
Datasheets often suggest that anhydrous and technical grades are interchangeable except for water content, but practical experience says otherwise. Water isn’t the only impurity at stake. Trace metal content, residual organic by-products, and handling contamination matter just as much. Over the years, our team has invested in spectrum analysis and micro-tracing equipment that pick up levels of iron, copper, or chloride well below the detection limits of traditional plant gear. More than once, a bottleneck in a customer’s batch was traced to a few ppm metal contamination from a competitor’s hastily-filled cylinder or substandard drum pump.
We source our reagents and components from tightly-screened producers and never allow unvetted suppliers. Protocols governing the cleaning, drying, and leak testing of cylinders are non-negotiable—small lapses here put whole production lots at risk. Since trimethylamine’s low boiling point means it can draw in air or moisture by simple atmospheric contact, our team trains on quick connection, flow control, and isolation valves designed in-house. The knowledge passed down from senior operators informs every cylinder fill, batch test, and customer shipment.
Handling trimethylamine [anhydrous] isn’t for the inexperienced. The gas’s flammability and strong odor demand purpose-built storage, leak detection, and well-rehearsed emergency protocols. Over the years, we have worked with fire marshals, compliance inspectors, and safety engineers to update our systems. Every storage area uses continuous gas monitors, multi-redundant venting, and high-integrity connections. Workers undergo annual on-site training for both routine and emergency scenarios. It only takes a brief lapse in shielding or purging procedures to create trouble.
There’s been a shift in recent years toward more stringent regulatory scrutiny, particularly in transport, environmental reporting, and end-use tracking. Our compliance record reflects proactive adaptation; whether it’s international dangerous goods (IMDG), workplace exposure limits, or strict customs paperwork, we maintain a full-time compliance desk handling documentation, training, and shipment security audits. Customers often depend on our experience to keep their processes safe and legal, especially amid the growing pressure from both authorities and neighboring communities. From securing sealed tankers to mapping out designated delivery routes, the lessons learned in previous years continue to shape every outbound load.
Building trust in trimethylamine supply takes more than just keeping product on spec. In our team, plant operators, chemists, and logistics specialists work directly with customers troubleshooting issues at every stage. A frequently asked question involves safe cylinder staging and pressure venting; our plant has suffered its own share of hiccups during valve connection or unexpected ambient warming. We use those lessons to help customers avoid problems in mixing rooms or during high-throughput batching.
Each new shipment brings some challenge—ranging from request for non-standard packaging to urgent turnaround for unplanned outages. Our ability to respond quickly depends on staff who genuinely know both chemical properties and plant-level problem solving. We’ve made after-hours site visits, coached maintenance crews on reclaiming off-spec material, and adapted batch schedules to avoid supplier-driven shutdowns. In all, technical support delivered by actual practitioners with real production experience tends to make the difference when high-value synthesis or just-in-time manufacturing depends on flawless amine supply.
Markets continue to tighten standards on contaminant thresholds and supplier traceability. The primary differentiator for our trimethylamine [anhydrous] remains consistency—year after year, batch after batch. Our traceability system logs full manufacturing, filling, and distribution history for every lot, matched by retention samples and ongoing stability testing. That way, if a problem crops up downstream, it’s not a guessing game—we pull records, investigate, and report transparently, giving users actionable information rather than run-around answers.
Our engagement extends beyond a single transaction. Many long-term buyers approached us after experiencing performance or safety issues with unproven suppliers or import-driven commodity sources. They share stories of delayed batch approvals, unexpected downtime, or off-grade finished goods traced back to poorly managed amine supply. The difference isn’t simply tighter specs—it’s the follow-through, troubleshooting, and infrastructure investment that sets a manufacturer apart from a trader or repacker. Market volatility, price pressures, and regulatory changes make long-term trust more valuable than the lowest sticker price.
We keep investing in both production efficiency and quality assurance. Retrofitting our distillation units for lower emissions, deploying higher sensitivity detectors, and standardizing isolation procedures help keep trimethylamine [anhydrous] pure and readily available. Offset against growing global demand, this approach secures supply without compromise. Digital tracking and upgraded process control add both safety and efficiency, letting us monitor conditions and respond before small issues become big ones.
From insight gathered collaborating directly with end-users—engineers, quality labs, plant managers—we continue tuning our systems not just to meet, but to anticipate market trends. The need for greener production, more sustainable raw materials sourcing, and lower energy footprints is driving an industry shift. We’re prepared to add capacity, investigate biobased feedstocks, and share environmental reports with downstream partners. A responsible amine manufacturer does not sit back waiting for regulations; we take the lead by harnessing the expertise already gained.
There are few substitutes matching the combination of volatility, basicity, and functional performance offered by trimethylamine [anhydrous] in synthesis. Colleagues in both research and industry confirm that attempts to swap in solution or solid analogs introduce more hurdles than solutions. Having robust, real-time quality control and reliable, experience-based supplier support isn’t a luxury—it’s essential to staying productive and competitive, especially as formulations grow more complex and demand keeps rising.
From our vantage point as a hands-on producer, the success of every kilogram shipped—the yield it supports, the consistency it brings, the safety it assures—reflects our people, our process, and our integrity as manufacturers. That is what distinguishes our trimethylamine [anhydrous], beyond a mere chemical—it's the outcome of real-world experience, day-to-day vigilance, and relentless improvement.