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HS Code |
196656 |
| Product Name | Tetradecanoyl Chloride |
| Cas Number | 112-66-3 |
| Molecular Formula | C14H27ClO |
| Molar Mass | 246.82 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 322.2 °C at 760 mmHg |
| Melting Point | 6-8 °C |
| Density | 0.950 g/cm³ at 25 °C |
| Refractive Index | 1.442-1.444 at 20 °C |
| Solubility | Reacts with water, soluble in organic solvents |
| Flash Point | 138.1 °C (closed cup) |
As an accredited Tetradecanoyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Tetradecanoyl Chloride is typically packaged in 250 mL amber glass bottles with tamper-evident seals and hazardous material labeling. |
| Shipping | Tetradecanoyl Chloride should be shipped in tightly sealed containers under an inert atmosphere, protected from moisture and incompatible substances. It is classified as a corrosive chemical and should be labeled accordingly. Transportation must comply with local, national, and international regulations to ensure safe handling and prevent accidental leakage or exposure. |
| Storage | Tetradecanoyl chloride should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from moisture, heat sources, and incompatible substances such as water, alcohols, and strong bases. Keep away from direct sunlight and sources of ignition. Use corrosion-resistant storage materials and ensure proper secondary containment to prevent leaks or spills. |
Applications of Tetradecanoyl Chloride in Industrial ManufacturingTetradecanoyl chloride acts as a key C14 acylating agent widely adopted by global manufacturers in selected specialty downstream industries. Due to its controlled reactivity and long-chain fatty acid structure, customers rely on this raw material for value-added derivatization processes where C14 functionality brings specific performance, regulatory, and physicochemical characteristics to end-use formulations. Below, we outline real-world B2B applications, corresponding compliance regimes, proven formulation ranges, points of process integration, and targeted end products. 1. Synthesis of Specialty Surfactants for Cosmetic and Personal Care ApplicationsAs a controlled intermediate, this raw material is utilized in the preparation of cationic and non-ionic surfactants, contributing C14 acyl groups for tailored amphiphilic balances required in personal cleansing, hair conditioning, and emulsion systems. Mid- and large-scale formulators in the personal care segment incorporate this raw material during quaternization, esterification, or amidation stages, where the finished surfactants must meet strict purity profiles and geographic regulations on fatty acid chain structures and residual chlorides for leave-on and rinse-off use. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Production of Lubricant Additives for Metalworking FluidsIndustrial lubricant additive manufacturers use this material in the acylation of polyamines or polyols, forming C14-functionalized esters and amides that impart tailored lubricity, dispersancy, and anti-wear properties. Compliance with heavy metal content requirements and performance testing is essential for downstream use in formulated fluids, especially under high-stress machining operations. Real-world dosing depends on base fluid compatibility, application temperature range, and final fluid classification. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Pharmaceutical Intermediate for Synthesis of Lipid-Based Drug Delivery SystemsDrug manufacturers utilize this material to acylate glycerols or aminoalcohols, creating C14-chain lipid excipients for controlled-release or solubilization applications. Use as a registered starting material in cGMP synthesis demands strict batch traceability and conformance to pharmacopoeial limits for free acid, color, and heavy metals. Real-world implementation focuses on scaling chain length distribution and purity during excipient synthesis for lipid nanoparticles, emulsions, and oral delivery platforms. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Advanced Polymer Modification: Functionalizing Specialty Polyamides and PolyurethanesPolymer producers incorporate this raw material as a chain modifier or end-group capping agent during the synthesis of high-performance polyamides and polyurethanes. C14 introduction tailors surface hydrophobicity, melt flow, and compatibility in specialty films, fibers, and foams. Usage must comply with sector-specific polymer standards, especially for regulated packaging resins or engineered components with direct/indirect food contact. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Synthesis of Quaternary Ammonium Compounds for Industrial BiocidesManufacturers in the biocidal sector depend on this material as a C14 acyl donor for the synthesis of quaternary ammonium surfactants, widely used as broad-spectrum disinfectants and antimicrobials. These compounds undergo strict regulatory scrutiny for purity, toxicity, and environmental impact in target markets where performance must be balanced with safe use concentration in commercial cleaning, food processing, and water treatment systems. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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In our years handling specialty chemicals, Tetradecanoyl Chloride (model: industrial grade 98.5% min) stands out as a trusted fatty acid chloride. The demand comes straight from downstream industries—pharmaceuticals, agrochemicals, advanced materials, surfactant synthesis. We know because our team produces this compound, batch after batch, under controlled conditions. Compared to standard fatty acid chlorides, its medium-length chain (C14) brings balance in reactivity and processability. Each drum loaded off our line reflects a combination of know-how, monitored raw materials, real-world filtration, and chemical discipline.
We receive natural vegetable oils and purified myristic acid as base materials. Consistency at this first step keeps the end product stable, with fewer impurities passing downstream. Our process uses a continuous chlorination system—hydrogen chloride reacts directly with the acid, followed by rapid phase separation. Every operator checks for residual acidity and color. Purity level 98.5% and above comes from this rigour—not just because of standards, but due to cumulative lessons from clients who reject any hint of byproduct. We notice that finer fractions—trace impurities, color changes—impact both their yields and downstream processing.
Taking pride in our filtration and distillation routines, we manage chlorine residue and color before packaging. Cleaning cycles receive extra scrutiny. When dust or micro-residue builds in holding lines, both odor and shelf stability slip. Our approach comes from years of running both small and large batches; customers who synthesize custom intermediates give feedback that links any upstream shortcut to costly rework. In Tetradecanoyl Chloride, quality rides on these production realities.
Crystal-clear clarity and a pale straw tint mark a good drum. Tetradecanoyl Chloride flows as a liquid at room temperature in warm climates, but in winter can solidify at about 40°C. For shipment, we insulate drums and use inner liners that keep moisture out—no one wants HCl fumes on opening. Odor is sharp and matches the fatty acid backbone, but we test every batch for traces of over-chlorination. Measured density falls between 0.894-0.896 g/cm³ at 20°C, blending fluidly with common organic solvents such as dichloromethane, toluene, and non-polar hydrocarbons.
From manufacturing lines, we see how moisture is always the enemy. Any trace of water triggers hydrolysis, generating free myristic acid and releasing corrosive hydrogen chloride. To avoid extra moisture content, our warehouse team deploys silica gel packs with every export. This isn’t just a QA checkbox—it comes from knowing that even a marginal contamination during transfer can ruin active batches for downstream users.
The heart of our business comes from buyers who use Tetradecanoyl Chloride as an acylation agent. We have worked with both large pharmaceutical intermediates manufacturers and custom molecule startups. Most seek this C14 chain for controlled reactivity—too short like lauroyl chloride and you lose hydrophobicity; too long, as in stearoyl chloride, and solubility in organic media diminishes. Our customers request this chain to build surfactants with specific melting points or to attach C14 moieties to drug intermediates, enhancing lipid solubility.
We have seen this molecule perform in cosmetic intermediates—a field where batch-to-batch consistency impacts rheology, feel, and long-term emulsion stability. Tetradecanoyl Chloride finds its role in the custom synthesis of esters and amides, both important in specialty surfactants and fine chemicals. For agriculture, processors request our drums to manufacture adjuvant molecules that ease the penetration of active pesticides. Each of these uses shapes how we control specification—too high in free acid, and downstream color or odor drifts. Too volatile, and the desired acylation doesn’t proceed efficiently.
Talking with technical teams who order repeat lots, we understand the selection isn’t random. They have tried other fatty acid chlorides, but Tetradecanoyl Chloride gives predictable behavior—flow, melting, color, and reactivity. Shorter chains introduce volatility or too much reactivity, causing unwanted side-products in mild conditions. Longer chains struggle with solubility and downstream process compatibility. In the middle, C14 offers a sweet spot for both synthetic yield and material handling. We keep infrared and NMR verification on-site to reduce structure and purity doubts from buyers; direct questions about odd carbon counts or minor halide content can be addressed from in-house data, saving weeks of trial-and-error at customer plants.
We have received questions from researchers developing new surfactant heads. Tetradecanoyl Chloride allows flexible design: make C14 esters or amides, and the product will perform—neither too greasy nor too waxy. Its moderate chain length helps achieve low cloud points in nonionic surfactant blends or create medium-foaming emulsifiers. By working with actual customer processes—sometimes joining their technical meetings—we offer suggestions about solvent handling, local venting, and batch-size adjustments. Feedback on failed couplings or discoloration prompts our engineers to re-examine storage, transfer processes, or even drum materials.
Clear procedures reduce hiccups. Our operators wear acid-block gloves, chemical goggles, and face shields at every production stage. Tetradecanoyl Chloride releases hydrogen chloride on exposure to air and water, so we supply it in lined steel drums with two-stage sealing. The difference this makes becomes clear during monsoon shipments—without liner upgrades, corrosion damages even steel drums and gives headaches on arrival at client warehouses.
From experience, we find that early attention to these hazards sets everyone up for fewer surprises. Training new staff on careful transfer, neutralization protocols, and real-time pH checks happens before anyone touches the line. Our lab ensures every batch has up-to-date documentation on chain length and purity, as customs authorities or multinational clients require real-time compliance data. This attention protects downstream worker safety as well as our standing with large international users.
Demand for acyl chlorides follows the push toward more tailored surface-active agents, cleaner pesticide formulation, and specialty organic syntheses. Over years tracking requests, we’ve adjusted our lot sizes, packaging, and even labeling to meet emerging regulatory frameworks. More customers are asking about reach and global chemical inventory registration.
Environmental and health standards keep rising, and buyers want direct assurance on residual contaminants—chlorine, acidity, impurities. Our ongoing audits with third-party labs and growing internal capabilities stem from these pressures. Customers want not just a COA, but also real-time temperature and humidity data for sea shipments. In the past, we underestimated the impact of storage temperature shifts; today, every export order comes with a data logger and shipment history accessible via QR code. Tallying shipment complaints now tells a better story: steady declines in off-spec returns.
Experience drives incremental upgrades. Years back, our complaints came from handling lines that introduced trace iron, discoloring the product. Analysis tracked the cause to outdated transfer pumps—a fix that seemed small but drove up both shelf-life and buyer confidence. We invested in lined, non-reactive pumps despite the extra cost. Our records link fewer quality claims directly to such investments.
Handling moisture contamination taught us another lesson. Replacing natural fiber drum seals with upgraded polymer liners cut down on hydrolysis incidents. After a run of negative customer feedback about drum “fuminess,” we revised both our winter storage and shipping protocols. By listening to incoming reports and prioritizing best practices, we cut spoilage risk and built longer customer partnerships.
Few manufacturers have the facilities or patience to hit consistent, high-purity runs at the C14 chain. Standard lauroyl (C12) or palmitoyl (C16) chlorides dominate the market, primarily due to easier raw material access. Tetradecanoyl Chloride demands more process controls; chain-length uniformity affects both melting and handling. From the manufacturer’s line, you see the micro-differences: pourability at varying temperatures, handling difficulty as ambient shifts, distinct odor notes, and shelf-life when exposed to the elements. These are challenges that don’t emerge from a distributor’s warehouse, but they matter at every scale, from 25 kg carboys to 250 kg drums.
We’ve run parallel batches on the same equipment using different chain lengths. The C14 drum clears a line faster than C16, owing to better flow at mild heat and lower wax content. Short-chained lauroyl chloride, for instance, evaporates faster and leaves more acidic vapor in air, creating a more aggressive workplace odor. These operator observations help explain why customers ask for precise chain lengths tied to their specific uses. Tetradecanoyl Chloride fits where both moderate melting and solubility matter.
Long-term reliability with this product comes from partnerships with direct users. Processors who blend in Tetradecanoyl Chloride target narrow functional ranges—emulsifier grades, active ingredient carriers, reaction intermediate pools. Regular direct feedback has led us to fine-tune packaging options and filter selections; sticky residue and micro-particles once caused measurable downtime at bigger custom plants. Lab-scale users need smaller packs and batch-level traceability. Our dedicated customer support specialists remain in direct contact with technical staff in pharma, agro, and materials companies. They flag new needs, guide us on evolving compliance requirements, and provide results of actual field tests, including observations on product behavior that don’t reach us through reports alone.
Scaling up Tetradecanoyl Chloride requires discipline and adjustment. The product that works in a small lab flask behaves differently in a 5000-liter reactor; the difference lies in heat transfer, agitation, and off-gas management. We offer engineering advice drawn from our own scaling events—such as adjusting quench rates or venting systems to handle hydrogen chloride build-up. Clients value this transfer of hands-on knowledge more than any generic technical data sheet.
Storage investments make a difference at both scales. Bulk buyers now insist on real tank-farm pump traceability and cleaning records after seeing cross-contamination with unrelated chlorides. Meanwhile, R&D departments ask for micro-scale verification; NMR spectra and chain-length guarantee batch-by-batch. We have embraced batch tracking and analytics drawn both from in-house and external labs, guided by the changing scale of our buyers.
Stable supply equals timely deliveries. Our experience with global shipments shows that delayed customs checks or missed labeling regulations can throw weeks off a project schedule. To prevent this, our team regularly updates documentation and aligns with the shipment protocols of new countries. Investing in better packaging and more reliable third-party warehouse partners translates into more secure, on-time delivery. We load our shipments into temperature-controlled containers only after confirming that shipping agents understand the handling precautions.
Bulk shipments require careful drum placement and shipment pre-cooling. Containerized shipments that sat in tropical humidity used to result in deteriorated product or local regulatory interventions. By working upstream with both shipping companies and regulatory bodies, we reduce surprises. The paperwork, regulatory compliance, and physical inspection all stem from direct experience—failure in one link can set off a chain reaction. We spend every quarter reviewing this critical feedback loop; our improvements come not from abstract process-improvement programs but from firsthand logistics records over hundreds of batches.
As the producer of Tetradecanoyl Chloride, ongoing investment in both technical and human resources becomes part of the business. Markets for high-purity chemicals are built on trust—every decision on plant upgrades, QA equipment, and operator training reflects both lessons learned and the competitive realities of specialty chemical production. Upgrades to analytical instruments—GC, NMR, IR—stem from real customer audits, not marketing. We know auditors check both our spec conformity and our long-term capacity to meet contract volume and purity.
By forging supply relationships based on reliability, quick technical support, and honest reporting of quality investigations, we maintain demand for Tetradecanoyl Chloride in an environment driven by both innovation and regulatory oversight. Our aim stays the same: deliver exactly what was promised, communicate risks if a deviation arises, and update both clients and staff on lessons from each mishap to prevent repeats. By staying close to those using the chemical every day, we contribute to better end products across multiple markets.