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Sodium Phenoxide

    • Product Name Sodium Phenoxide
    • Alias sodium-phenoxide
    • Einecs 203-977-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    340660

    chemical_name Sodium Phenoxide
    cas_number 139-02-6
    molecular_formula C6H5NaO
    molar_mass 116.09 g/mol
    appearance White to off-white crystalline powder
    solubility_in_water Highly soluble
    pH Strongly basic in aqueous solution
    density 1.53 g/cm³
    odor Faint phenolic
    boiling_point Decomposes before boiling
    synonyms Sodium phenate, Sodium monophenoxide
    storage_conditions Keep container tightly closed, store in a cool and dry place
    reactivity Reacts with acids to form phenol
    uses Intermediate in organic synthesis

    As an accredited Sodium Phenoxide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500g white HDPE bottle labeled "Sodium Phenoxide," featuring hazard symbols, tightly sealed screw cap, and batch information printed clearly.
    Shipping Sodium Phenoxide should be shipped in tightly sealed, chemically resistant containers to prevent moisture absorption and contamination. Handle with care, and clearly label with appropriate hazard warnings. Transport in accordance with local, national, and international regulations for corrosive and combustible materials. Avoid contact with acids and strong oxidizers during shipping and storage.
    Storage Sodium phenoxide should be stored in a tightly sealed container, protected from moisture and air, as it is hygroscopic and reacts with acids and carbon dioxide. Keep the container in a cool, dry, well-ventilated area, away from incompatible substances such as strong acids and oxidizing agents. Label the storage area clearly and ensure that only trained personnel access the chemical.
    Application of Sodium Phenoxide

    Applications of Sodium Phenoxide in Industrial Manufacturing

    Sodium Phenoxide serves as a critical intermediate and synthesis reagent across several well-established chemical processing sectors. As a manufacturer with decades of production and application experience, we supply Sodium Phenoxide for downstream clients who formulate precise products where molecular integrity, purity, and processing reliability have a direct impact on finished material qualities and regulatory approval. Below, we detail key downstream application tracks, each aligned with confirmed industry requirements, specific processing integration points, compliance frameworks, and final output materials.

    1. Phenolic Resin Synthesis for Industrial Adhesives

    Major resin producers rely on Sodium Phenoxide as a phenolate initiator in the alkali-catalyzed condensation reaction between phenol and formaldehyde. Sodium Phenoxide’s consistent purity ensures predictable molecular weight distribution and cross-linking density, which control the heat stability and structural strength of phenolic adhesives used in plywood manufacturing, refractory bonding, and heavy-duty edge tapes. Our customers demand fully traceable, impurity-controlled batches to meet downstream certification audits.

    Industry compliance standards

    • ASTM D1151 (Standard Specification for Phenolic Resins for Bonding Plywood)
    • JIS K 6911 (Japan Standard for Phenol-Formaldehyde Resins)
    • ISO 9001 certified manufacturing quality systems
    • EPA Title VI (Formaldehyde Emission Standards for Wood Products)

    Typical usage ratio

    • 0.4–1.2% by weight relative to total phenol content, adjusted based on targeted gel time and final polymer viscosity requirements

    Downstream process integration

    • Added to the initial reaction kettle post-melting of phenol, prior to controlled formaldehyde addition and exothermic polymerization

    Final product types

    • Phenolic adhesives for plywood lamination
    • Industrial bonding resins for brake linings, foundry molds
    • High-heat resistant laminates

    2. Pharmaceutical Synthesis: Paracetamol (Acetaminophen) API Manufacturing

    Global pharmaceutical facilities source Sodium Phenoxide for Ullmann ether synthesis, serving as an indispensable nucleophilic agent in the production of paracetamol active compound. As batch reproducibility and impurity profile directly influence API assay and patient safety, we maintain full cGMP batch traceability and ultra-low metal content below pharmacopeia thresholds, ensuring finished paracetamol meets pharmacopoeial release specifications worldwide.

    Industry compliance standards

    • USP, EP, BP monographs for Paracetamol (Acetaminophen) API
    • ICH Q7A (Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients)
    • 21 CFR Part 210/211 (FDA cGMP for finished pharmaceuticals)
    • Chinese Pharmacopoeia (CP, ChP) requirements for pharmaceutical intermediates

    Typical usage ratio

    • 1.05–1.20 molar equivalents per mole of p-nitrochlorobenzene, with adjustment based on impurity risk assessment and minimization of byproduct formation

    Downstream process integration

    • Charged at the nucleophilic aromatic substitution phase, facilitating etherification before the subsequent reduction and acetylation operations

    Final product types

    • USP/EP Grade Paracetamol (Acetaminophen) API
    • Bulk intermediate stages for paracetamol formulations

    3. Dye and Pigment Manufacture: Azo and Triphenylmethane Dyes

    Sodium Phenoxide acts as a key precursor in constructing chromophore frameworks during azo dye coupling and triphenylmethane dye condensation. Its reactivity governs the hue, purity, and tinctorial strength of dyes destined for textiles, paper, and plastics. Bulk dye plants depend on reproducible assay and color development, requiring feedstocks that pass continuous in-process QC for intermediate grades and heavy metal content.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (Textile chemical safety)
    • EN 71-3 (Safety of toys: migration of certain elements)
    • REACH Regulation (EC) No 1907/2006 for chemical substances
    • ISO 18314-1 (Analytical color measurement validation)

    Typical usage ratio

    • 0.8–1.3 molar equivalents relative to primary aromatic amine or diazonium salt, precisely set for color intensity targets and to minimize unreacted substrate

    Downstream process integration

    • Charged after initial diazotization or condensation step, usually in alkaline aqueous media, to promote specific nucleophilic substitution or coupling reactions

    Final product types

    • Sulfonated azo dyes for polyester and nylon
    • Paper-colorant basic dyes
    • Triphenylmethane dyes for stamp inks and textile marking

    4. Agrochemical Synthesis: Herbicides and Fungicide Intermediates

    Producers of phenoxy herbicides and select agricultural fungicides integrate Sodium Phenoxide as a key nucleophile for ether linkage reactions and aromatic substitution. Its controlled reactivity determines the molecular selectivity and environmental emission footprint of downstream actives, with trace levels constantly monitored to ensure no toxic byproducts migrate into agricultural supply chains.

    Industry compliance standards

    • FAO/WHO Specification for Pesticide Products
    • EPA FIFRA (Federal Insecticide, Fungicide, and Rodenticide Act)
    • ISO 9001 and ISO 14001 process management for agrochemicals
    • Local Maximum Contaminant Levels (MCLs) for pesticide residues

    Typical usage ratio

    • 1.0–1.5 molar equivalents per target aromatic substrate, adjusted according to kinetic studies for each technical material route

    Downstream process integration

    • Enters the synthesis vessel post-hydrolysis for nucleophilic substitution reactions in ether or ester bond formation, followed by purification and formulation steps

    Final product types

    • 2,4-Dichlorophenoxyacetic acid (2,4-D) herbicide technical concentrates
    • 3,5-Dichlorophenol-based systemic fungicides
    • Pre-emergence herbicide intermediates

    5. Synthesis of Diphenyl Ether for Industrial Antioxidant Production

    In antioxidant manufacturing, Sodium Phenoxide provides the reactive phenoxide anion for the Williamson ether synthesis of diphenyl ethers, which serve as intermediates for the production of heat-stable phenolic antioxidants utilized in rubber, plastics, and lubricants. Commercial-scale plants require precise addition and continuous process monitoring to suppress byproducts and guarantee reproducibility in antioxygenic performance.

    Industry compliance standards

    • ISO 21461 (Rubber and rubber products—Determination of antidegradants)
    • ASTM D4676 (Standard Classification for Rubber Antioxidants)
    • FDA 21 CFR 178.2010 (Antioxidants and stabilizers for polymers)
    • TSCA (Toxic Substances Control Act) registration for intermediates

    Typical usage ratio

    • 1.05–1.15 molar equivalents to the halogenated benzene substrate, periodically adjusted based on process mass balance and thermal yield optimization

    Downstream process integration

    • Added to the main reaction phase kettles after premixing with sodium hydroxide, driving the etherification cycle before final distillation and crystallization

    Final product types

    • Diphenyl ether intermediates for hindered phenolic antioxidants
    • Finished antioxidant blends for tire, elastomer, and plastic modification industries
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    Certification & Compliance
    More Introduction

    Sodium Phenoxide: A Manufacturer’s View on a Dependable Chemical Asset

    Crafting Sodium Phenoxide: Realities from a Production Shop Floor

    The shift from phenol to sodium phenoxide marks a common but subtle transformation in industrial chemistry. That change has played out countless times in our reactors. Producing sodium phenoxide (commonly recognized as sodium phenate) takes more than just following a recipe. Each batch must show the consistency chemists and formulators expect. We rely on tried-and-true reactions: phenol meets high-purity sodium hydroxide, and that neutralization produces the crystalline powder or flakes that chemists recognize immediately by their faint, characteristic odor and pale hue. You will find a product with few visible impurities, because temperature, reaction duration, and raw materials leave almost no margin for error. In our experience, labs and plants both appreciate this reliability.

    Model choices may seem minor to outsiders. For insiders, details like particle size, moisture content, and packaging type play a direct role in success. Weʼve learned that pharmaceutical customers expect no more than trace sodium carbonate. Those working with agrochemicals or dyes prioritize flow behavior. Most batches leave our site as a fine, free-flowing white powder with purity often exceeding 99%. We deliver sodium phenoxide based on customer needs: granular, flake, fine powder. Our refining and drying steps get scrutinized batch after batch. This is not simply about box-checking; it’s about making formulas—and people—productive.

    What Sets Sodium Phenoxide Apart in the Lab and in Scale-Up

    Sodium phenoxide doesn’t stand alone, and comparisons matter. Anyone synthesizing aromatic ethers, or setting up Williamson reactions, likely knows both sodium and potassium phenoxides. Potassium analogs react faster in some organic reactions, but sodium phenoxide offers a balance. Reactivity, cost, and ease of storage matter in daily work. Sodium phenoxide remains stable under dry air—even over months of storage. Many of our clients, especially where volumes run to the multi-ton level, find that sodium phenoxide gives consistent conversion without forcing re-investment in storage technology.

    Handling always becomes a focal point. Sodium phenoxide diverges sharply from the corrosiveness and fume issues of sodium alkoxides like sodium methoxide or sodium ethoxide. Moisture pickup can still be a concern, so we prioritize tight sealing or inert gas purging. Our process engineers developed systems to keep the product dry from our dryers to customer filling lines. Unlike some lower-boiling chemical bases, sodium phenoxide travels long distances without decomposition. In frequent conversations with downstream users, we remind them that well-capped containers and minimal water exposure maximize shelf life.

    Sodium phenoxide also stands out for its solubility and workability. It mixes with water and some organic solvents without issue, letting it disperse fully into various formulations. For dye synthesis, resin modification, or certain pharmaceutical intermediates, a workable solution phase is vital. Some other bases leave a heavier residue or lead to excessive byproducts. Keeping byproduct burden low means easier purification downstream—a point research chemists never overlook. That helps scale-up and also matters for quality assurance. From our troubleshooting records, we know cases in textile dye formation where sodium phenoxide cut unwanted impurities by up to 20% relative to lower-cost, less refined alternatives.

    Trusted Uses Based on Laboratory and Factory Applications

    Customers find sodium phenoxide at the heart of hard-working chemistry. Weʼve supplied it to makers of phenoxy-ethers, particularly for the manufacture of antioxidants, fungicides, and select pharmaceuticals. It enables the etherification of halogenated aromatics in the Williamson synthesis, a common route for making diaryl ethers. In the dye and pigment fields, sodium phenoxide’s strong nucleophilic character allows crisp, selective ring reactions with electrophiles—a needed virtue when production waste cuts into efficiency.

    In our technical support log, resin manufacturers stand out as repeat users. They use sodium phenoxide to introduce phenoxide moieties. This opens up possibilities in engineering plastics, helping tailor polymers with more robust thermal and chemical resistance. In our own studies with clients, we’ve seen sodium phenoxide-derived polymers outperform baseline phenolic resins, especially under humid, high-temperature environments. That capability stems from the reactivity profile of sodium phenoxide—without over-alkalizing or introducing excess sodium contamination.

    Pharmaceutical synthesis brings out another layer of detail. Sodium phenoxide fits into multi-step routes, working as a base or nucleophile in aromatic coupling or deprotonation. Its performance in regulated settings comes down to impurity management and batch-to-batch reproducibility. Customers trust that our product stays within specifications, from loss on drying to trace metals. We keep these standards high through constant in-process monitoring.

    Operational Concerns from a Manufacturing Standpoint

    Making sodium phenoxide is more than a textbook process. The selection of sodium hydroxide grade, water content in phenol, and timing can all change the outcome. Even minor contamination by sodium carbonate, unreacted base, or water affects reactivity and storage. Over years of manufacturing, we’ve adjusted both input filtration and reactors to maximize product reliability. Recovery lines and closed conveyors keep occupational exposure under control and protect against clumping or caking. We collect and analyze samples from every production batch. Outliers rarely escape detection, because every delivery carries our factory’s name and reputation.

    We have invested in worker protection and bulk-handling automation, because the powder's caustic properties require respect. Respiratory and skin exposures, although lower than sodium alkoxides, remain relevant. We offer packaging in lined, moisture-tight drums or supersacks depending on downstream operation needs. With modern automation, we minimize human contact and environmental releases. Our long-term maintenance logs show that equipment wears faster if powdered sodium phenoxide migrates into seals or bearings. We use specialized filters and airlocks, and schedule quarterly reviews to minimize downtime.

    In winter or in humid shipping climates, the risks of caking or unwanted hydrolysis go up. We remind logistics partners to keep containers dry and shaded from heat sources. Reusing open drums may sound cost-effective, but residue and moisture pick-up eliminate any savings. Technical support walks customers through best practices. Over time, customers using best-in-class handling cut loss rates—not just in the warehouse, but all the way at the mixing tank.

    Meeting Specifications Without Cutting Corners

    Chemical buyers often ask for documentation and certifications. We see this not as a paperwork burden, but as a sign that quality and purity influence process reliability downriver. We commit each batch to analytical verification—titration for base content, GC/HPLC for organic residues, and tests for trace sodium carbonate and chloride. Batches meet strict standards for moisture—low enough that shelf life and reactivity aren’t compromised. Our own QA staff accept no deviations.

    Suppliers who cut corners create real world headaches on production lines. Poorly controlled sodium content, excessive carbonate, or colored impurities slow down filtration and affect product color. Over years, we've collaborated with users to offer viscosity data, particle-size distribution, and solvent compatibility readings based on actual performance. We're happy to explain differences in functional purity: even two sources showing “99%” purity can perform quite differently. Small details in crystallinity, residual phenol, or even packaging type can steer results dramatically, especially in synthesis where one impurity creates costly byproducts.

    Efficiency and Sustainability: Shaping Tomorrow’s Phenoxide Output

    Committed manufacturers do more than meet specs. Improvements in reactor design, recovery systems, and waste handling save energy and raw material. Sodium phenoxide production yields salty waste streams and sometimes phenol traces. Our site reprocesses much of this back to upstream reactors, reducing both waste and cost. We strive for a tightly closed material cycle—recovering, treating, or recycling caustic liquors. We are working toward lower net energy use per ton produced, because economic stability and environmental responsibility bring mutual benefits. Regulations move fast and unpredictably, so our compliance engineers track limits on airborne sodium emissions and wastewater discharge. Our chemists lead ongoing projects to identify greener routes, or at least routes with lowered water demand.

    We remind downstream users of sodium phenoxide’s role in making more durable, longer-lasting products. Demand grows for polymers and chemicals that perform at high temperatures, with less environmental burden over their lifespan. Sodium phenoxide helps achieve this by enabling robust chemical bonds in manufactured resins and specialty plastics. Removing heavy metals and persistent organic residues at the source means finished products meet regulatory and company goals for safer chemical profiles. We view this as both a technical and a moral responsibility.

    Lessons Learned from Decades of Actual Manufacturing

    Mistakes in chemical manufacturing are expensive—sometimes measured in hours lost, sometimes in thousands of dollars, occasionally in lost trust. We don’t overpromise on sodium phenoxide. Budget options exist, but reliability isn’t about cutting initial costs. Over the years, some users switch back to us after cheaper alternatives prove inconsistent or troublesome in scale-up. We use direct feedback to inform process tweaks. Faulty packaging, inconsistent drying, or untimely delivery can ripple through any client organization—so our logistical staff maintains close connections with carriers, customs, and warehouse operators. You won’t hear us touting lowest price, but we stand behind clean delivery, on-time schedules, and clear documentation.

    Technical support means more than answering safety-data requests. Bulk buyers often request mixing advice, documentation for audits, or recommendations for process troubleshooting. We document long-term storage conditions, batch lot retesting, and product compatibility advice for customers ramping up new formulations. Our site records show that attentive follow-up often prevents technical hitches years down the line. For us, it’s about transparency in what our product can do—and what it can’t.

    Real-World Impact: User Stories from the Field

    Stories from chemical users matter far more than technical bulletins. One customer in central Europe scaled up production of etherified flame retardants; switching to our sodium phenoxide let them trim off-color artifacts by nearly one-third. Another, an Asian pharmaceuticals site, regularly conducts multi-kilo aromatic alkylations. Stable storage of sodium phenoxide—achieved by adopting our modified drum liners—let them reduce wastage over extended shut-downs. Resin producers, seeking edge retention at high temperatures, reported improvements in product toughness after optimizing their reactant ratios with our technical guidance.

    We learn from these stories, too. Early on, insufficient coordination around moisture-triggered agglomeration created stir-in problems for some clients. Addressing this with better inner liners, nitrogen blanket options, and improved drying slashed complaints drastically within a single year. Our strategy stems from sitting down with users—hearing real pain points and clarifying the lab-to-plant pipeline.

    Facing Challenges and Moving the Industry Forward

    Sodium phenoxide production does not avoid challenges. Fluctuating phenol prices, energy volatility, and supply disruptions all require mitigation. We develop supply diversity through approved alternate vendors and keep at least a month of critical inventory to buffer our clients’ own production planning. Some specialty customers require tailored blends—down to micro-levels of added stabilizers or unique consistency measures. Our mixing and finishing operations adjust to these needs without losing sight of purity or safety.

    Sodium phenoxide customers must stay abreast of regulatory shifts. EU REACH, China’s evolving guidelines, and US EPA standards impact not just us, but all users. We participate in industry forums that track legal and safety developments—applying improvements in hazard labeling, transportation security, and downstream traceability. Our investment in full digital traceability means customers receive a documented trail from raw phenol through delivered drum.

    Key Differences: Sodium Phenoxide vs. Other Choices

    Users sometimes ask why not move to potassium phenoxide, sodium alkoxides, or even older acid-catalyzed routes. Our experience shows that sodium phenoxide walks a pragmatic path: it has a manageable balance of reactivity, storage ease, safety, and overall cost. Potassium phenoxide can be more reactive, but potassium salts are more hygroscopic, demanding more cautious handling. Potassium salts can be harder to source. Sodium alkoxides, broadly used as strong bases, raise safety risks in large facilities—prompting countermeasures for flammability and fume control. Sodium phenoxide offers strong enough nucleophilicity for a wide menu of reactions, yet it behaves in a mild enough way that plant environments handle it with routine protective gear and moderate engineering controls.

    Compared with caustic soda directly, sodium phenoxide brings greater selectivity and does not promote rampant side-reactions in complex aromatic chemistry. Customers who substituted sodium methoxide or ethoxide for phenoxide often returned to our product after encountering low yields or rapid decomposition in heat-sensitive syntheses. The fine balance between reactivity and selectivity cannot be overlooked, especially in tight-tolerance production routines. We advise formulators to weigh these points alongside cost and supply when making a sourcing choice. Our technical support stands by as a sounding board for anyone weighing alternatives.

    Launching Better Collaboration: What Manufacturers Bring to the Table

    A manufacturer’s role centers not just on chemistry, but on stewardship. This means making the product, supplying clear data, and advising wisely on its use. It involves collaboration, shared troubleshooting, and continuous improvements that flow in both directions—manufacturer to customer, and customer to manufacturer. Sodium phenoxide production connects us with a web of users across pharmaceuticals, agriculture, construction materials, and plastics. Our experiences reinforce that open communication shortens learning curves and keeps both sides out of trouble.

    We stick with sodium phenoxide as a mainstay because its balance of usability, safety, and performance opens doors in both traditional and evolving sectors. The feedback from long-term partners tells us this compound will endure as a staple. Refinement will continue, across process, logistics, and regulatory fronts. As innovation proceeds, consistent quality and respect for user needs will remain our foundation.