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Sodium 4-Chloro-2-Nitrophenoxide

    • Product Name Sodium 4-Chloro-2-Nitrophenoxide
    • Alias Sodium 4-chloro-2-nitrophenolate
    • Einecs 217-678-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    746084

    Product Name Sodium 4-Chloro-2-Nitrophenoxide
    Chemical Formula C6H3ClNNaO3
    Appearance Yellow to orange powder
    Solubility In Water Soluble
    Melting Point Decomposes
    Cas Number 7512-30-7
    Storage Conditions Store in a cool, dry place
    Hazard Class Irritant
    Synonyms Sodium 4-chloro-2-nitrophenolate
    Ph Basic aqueous solution

    As an accredited Sodium 4-Chloro-2-Nitrophenoxide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Brown glass bottle, 25g, tightly sealed with a screw cap; white hazard label displaying chemical name, quantity, and hazard symbols.
    Shipping Sodium 4-Chloro-2-Nitrophenoxide should be shipped in tightly sealed, chemical-resistant containers, clearly labeled with hazard information. It must be transported as per local regulations, typically as a hazardous chemical, protected from moisture, heat, and incompatible substances. Use appropriate cushioning and secondary containment to prevent leaks or spills during transit.
    Storage Sodium 4-Chloro-2-Nitrophenoxide should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from incompatible materials such as acids and oxidizers. Protect from moisture, direct sunlight, and sources of ignition. Clearly label the storage container, and keep it isolated from food and combustible substances. Use appropriate personal protective equipment during handling and storage.
    Application of Sodium 4-Chloro-2-Nitrophenoxide

    Applications of Sodium 4-Chloro-2-Nitrophenoxide in Industrial Manufacturing

    Sodium 4-Chloro-2-Nitrophenoxide serves as a critical intermediate in several industrial sectors. Our team manufactures this high-purity raw material specifically for formulated usage in each chemical segment, responding to strict industry benchmarks and downstream production needs.

    1. Pharmaceutical Intermediate Synthesis

    Major pharmaceutical companies employ this material in synthesizing complex organic intermediates, especially those utilized in the preparation of antibacterial and anti-inflammatory actives. The compound participates as a nucleophilic aromatic substituent during multi-step syntheses, particularly for sulfa drugs and heterocyclic scaffolds, delivered under stringent contamination controls. Our material supports robust batch-to-batch consistency for regulated pharmaceutical manufacturing environments.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • United States Pharmacopeia (USP) where required for intermediates
    • European Pharmacopoeia pre-intermediate criteria
    • REACH and TSCA registration for raw material imports

    Typical usage ratio

    • Used at 0.5–1.2 molar equivalents relative to primary amines or heterocycle precursors; dosage varies by step yield and desired substitution efficiency

    Downstream process integration

    • Introduced at the nucleophilic substitution or aromatic amination stages in multi-step API syntheses
    • Dissolved in DMF, DMSO, or other aprotic solvents under nitrogen; followed by reaction with secondary raw materials under controlled temperature

    Final product types

    • Sulfanilamide-based pharmaceuticals
    • Intermediate scaffolds for fluoroquinolones
    • Benzoxazole and benzimidazole derivatives
    • Bulk APIs exported for global formulation

    2. Agrochemical Intermediate for Herbicide Manufacturing

    The compound acts as an efficient building block during synthesis of specialized agrochemicals, particularly pre-emergence herbicides. Technical teams use it in condensation and cyclization reactions with chlorinated aromatic substrates, supporting cost-effective herbicide molecule design. Process engineers maintain stringent batch records and compliance with residual limits for export-oriented agrochemical formulations.

    Industry compliance standards

    • FAO/WHO Specifications for pesticide technical concentrates
    • US EPA 40 CFR Part 180 tolerance requirements for impurities
    • ISO 9001:2015 certified QC systems for batch qualification
    • Globally Harmonized System (GHS) for transport and labeling

    Typical usage ratio

    • 5–15% by weight in typical pre-condensation reactions as aromatic precursor; precise amount adjusted for desired chain length and ring closure efficiency

    Downstream process integration

    • Charged into stirred tank reactors with base and co-reactants for cyclization; process proceeds at 60–120°C under controlled agitation
    • Resulting intermediates undergo purification and conversion in downstream active ingredient finishing lines

    Final product types

    • Chloronitroaniline-based herbicides (e.g., trifluralin derivatives)
    • Phenoxy herbicide intermediates
    • Pesticide synthesis intermediates for third-party compounders
    • Technical grade herbicide concentrates

    3. Dye and Pigment Intermediate for Specialty Colorants

    Leading colorant producers rely on this substance during synthesis of specialty dyes and pigments, including azo and nitro derivatives for high-performance applications. Chemists use it for coupling reactions with aniline or phenol-based agents, supporting chromophore introduction and molecular modification. We assure trace impurity controls meet end-user product stability and regulatory constraints.

    Industry compliance standards

    • OEKO-TEX Standard 100 for restricted substances in textile dyes
    • EN 71-3 chemical safety standards for pigments in toys
    • ZDHC MRSL compliance (apparel sector)
    • Globally applicable technical grade specifications

    Typical usage ratio

    • 2–10% by weight of total dye batch; final quantity determined by targeted chroma intensity and end-use application purity requirements

    Downstream process integration

    • Added in coupling stage of azo dye synthesis, often under acidic or neutral conditions
    • Feeds into pigment synthesis reactors for aromatic ring modification, allowing custom color tuning at molecular level

    Final product types

    • Reactive textile dyes (for cotton, viscose)
    • High-lightfast industrial pigments
    • Organic pigments for inks
    • Dyes for leather and plastics

    4. Analytical Reagent Preparation for Laboratory Use

    Analytical chemistry suppliers utilize this compound as an intermediate in reagent kits designed for spectrophotometric and environmental assays. The molecule’s substitution pattern enhances detection sensitivity for nitroaromatic colorimetric analysis, especially in heavy metal and anion determinations. We manufacture to analytical grade criteria, ensuring minimal trace by-product content and stable performance in downstream quantitative applications.

    Industry compliance standards

    • ISO 17034:2016 for reference material production
    • ASTM E288 for laboratory reagent quality
    • RoHS and REACH for analytical chemical shipments
    • Lot-specific CoA traceability for laboratory use

    Typical usage ratio

    • 1–3 mg/mL final solution strength; ratio defined by assay method and targeted analytical sensitivity

    Downstream process integration

    • Formulated into buffer or indicator reagent concentrates
    • Dissolved or pre-complexed in analytical kits for onsite or research laboratory use

    Final product types

    • Colorimetric detection kits for water contaminants
    • Spectrophotometric assay reagents
    • Chromogenic reference mixes
    • Specialty indicator solutions for laboratory QC
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    Certification & Compliance
    More Introduction

    Sodium 4-Chloro-2-Nitrophenoxide: Insights from Our Factory Floor

    Manufactured for Reliability

    We have spent years perfecting the synthesis and quality control behind Sodium 4-Chloro-2-Nitrophenoxide. Not many outside this work realize how tiny changes in moisture or reaction conditions can shape a batch’s physical character or purity. Chemists and production engineers in our plant don’t lose sight of this. Our process begins at the reactor—every kilo stands as a marker of our facility’s hands-on oversight, from the initial mixing of raw precursors to the final drying stage.

    This compound, showing up with the rich yellow hue right at the filter, consistently confirms its identity by its spectral fingerprint and melting point, both benchmarks our QC team takes seriously with every lot.

    Understanding Its Purpose in Application

    Some see Sodium 4-Chloro-2-Nitrophenoxide as one chemical among thousands. On our end, years of feedback from dye developers and pharmaceutical research labs have shown this isn’t just another aromatic nitrophenol derivative. Its sodium salt structure delivers rapid dissolution in water—something textile, pigment, and agricultural researchers often call out as a deciding advantage. Trying to handle the neutral phenol or the potassium analog can end up causing awkward solubility challenges, slower reactions in batch systems, or unexpected residues in final formulations. Our sodium-based product remains stable and dissolves predictably, helping chemists avoid those wasteful cycle times.

    Laboratory teams lean on this material in azo- and quinoid-coupling, searching for strong electron-withdrawing characteristics in a reliable scaffold. For them, this compound’s para-chloro and ortho-nitro substitutions make the difference—steering reactivity along a narrow, dependable range. Through the years, several development projects have pointed out how even minor shifts in substitution, like a missing chlorine or an isomeric nitro group, bring out different kinetic profiles and less predictable intermediates. The product we manufacture serves as a stable platform, so researchers aren’t left troubleshooting unexplained yields or purity drifts.

    Specifying the Model—Why We Stay on a Single Path

    Some buyers look for wide-ranging grades or custom sodium salts. We focus all efforts on a single, verified model—ensuring consistency and reliability at scale. Our Sodium 4-Chloro-2-Nitrophenoxide comes as a free-flowing, yellow crystalline powder, with sodium content and moisture levels tracked by the shifts we’ve seen emerge over repeating annual runs. From days of customer audits to their in-plant observations, partners tell us they look for batches with minimal caking and low dusting. With investment in controlled-atmosphere packaging, we are able to mitigate these risks, based on direct feedback from end users who encountered bridging and handling trouble from older samples or less stringent supply chains.

    Purity reports and trace ion content aren’t academic targets on paper for us—they reflect the needs of real-world formulators who can’t afford business losses over an unaccounted impurity or a slight sodium excess that triggers secondary issues in other sensitive ingredients. By sticking with a single model produced in a controlled campaign, we offer a material that rarely throws curveballs at its users.

    What Sets Our Process Apart

    More than one competitor brings this chemical to market. Comparing samples over the years has shown us some companies skip careful washing or try to speed up filtration—shortcuts that can leave trace organic solvents or inconsistent particle sizes. In process chemistry, neither regulators nor well-seasoned technical buyers give much patience for those sorts of lapses. We stick to invariant process parameters, with full traceability back to our raw chemical sourcing and batch notes. This focus comes from years of troubleshooting contaminant issues, where skipping a wash led to inconsistent GC-MS readouts from batch to batch.

    On texture and granularity, users have repeatedly pointed out that unevenly prepared salts cause material handling headaches—especially in automated feeding systems. We actively dial in dryer temperatures, sieve mesh sizes, and humidity in the final packaging room. Our sodium salt flows cleanly, no matter the season, despite the region’s frequent monsoon humidity or winter chill.

    Perspectives from Continuous Use

    Research teams sometimes ask us how this sodium salt fares compared to the potassium or lithium versions, or the non-salt neutral form. From our vantage point, sodium delivers a sweet spot—reasonably active in organic transformations, with less deliquescence and less tendency to form sticky lumps during storage. In contrast, potassium salts may offer different dissolution speeds, but often come with handling trade-offs. The sodium version, by way of its lower molecular weight, also proves more cost-effective.

    Having received years of feedback, we’ve observed buyers gravitating toward sodium for its easier inventory management and lower hazard potential, especially when compared to using free phenolic acids, which tend to irritate skin and eyes. Safe handling protocols are still central to operations, but users have reported that our sodium-based offering reduces workplace incident rates compared to neutral or acidified analogs.

    Facing Market Challenges

    Supply disruptions and raw material price swings affect every manufacturer sooner or later. In times when upstream intermediates get tight, especially chlorinated or nitrated benzoic acid derivatives, we fall back on local supplier relationships built over decades, not one-off brokers. This doesn’t just keep the plant running—it ensures we won’t be forced to experiment with lower quality or uncertain starting materials.

    The reality is, chemical buyers push hard for cost savings, but at our plant, we’ve learned chasing the lowest price ends up pushing troubleshooting costs higher. One sharp spike in raw cost two years ago showed us: the savings vanished after only a few troubleshooting calls from customers who saw inconsistent batch color or offbeat IR peaks from cheaper precursors. Sticking with known suppliers and holding a modest raw stock buffer in our warehouse prevents headaches and ensures quality at the vessel.

    Environmental Responsibility and Safety

    Environmental stewardship isn’t an afterthought. Our team tracks every solvent drum and every outgoing effluent stream. The production involves organic solvents and mineral bases—two regimes known to leave their mark if handled carelessly. Closed-loop solvent recovery and wastewater treatment with periodic third-party audits keep our impact to a minimum. Operators receive ongoing training, as it only takes a couple of diverted liters to violate compliance or sour years of good relations with regulatory bodies.

    On the user’s end, we understand that safe handling and proper labeling matter as much as the actual product itself. Our containers feature clear hazard communication to avoid mix-ups in busy stocks rooms. By sticking with high-purity specifications, users experience reduced exposure to secondary irritants or allergens that could otherwise accompany products cut with unknown diluents or crude intermediates.

    Support from Direct Experience

    Technical teams sometimes phone in with questions about the best storage conditions for the sodium salt, or the likelihood of discoloration under varying light. Here’s what we’ve seen: Storing the product in a tightly sealed drum, out of direct sunlight and away from excess humidity, keeps the powder vibrant and analysis values steady for well over a year. That’s based on tracking multiple lots stored across different warehouse setups, not just a textbook guess.

    We have taken pride in the call logs and troubleshooting notes we’ve accumulated, which run deeper than many realize. From preventing accidental cross-contamination during bulk transfers to addressing occasional caking during summer shipments, every challenge has taught us more about keeping the whole supply chain running smoothly.

    Feedback and Continuous Improvement

    Critiques from users do not fall on deaf ears here. One round of customer input led us to refine our packaging by switching from kraft to high-density polyethylene liners—simple changes that cut the incidence of powder ingress by over sixty percent. Another batch of inquiries sparked a tweak in the drying phase, cutting one troublesome side reaction that emerged in rare summer heatwaves. Our lab staff routinely runs customer-supplied test procedures alongside our own, confirming performance and compatibility. This isn’t busywork; end results actually get back to the process engineers, who adjust parameters accordingly.

    A candid relationship with research chemists and industrial scale users pushes our team to document deviations, respond candidly to unexpected results, and jointly troubleshoot long-term challenges. Thinking the work ends at the shipping dock is shortsighted—true performance is measured by repeat orders and by clients who offer constructive, not always congratulatory, feedback.

    Why Our Sodium 4-Chloro-2-Nitrophenoxide Holds Value

    Talking to buyers reveals a few key patterns: availability counts, but predictability counts even more. Labs don’t want to revalidate protocols after every shipment. Formulators want zero guesswork in purity or sodium content. The history of this product in our hands, built from repeated campaigns, tracked data sheets, and evolving process notes, provides that needed transparency.

    Our customers’ priorities focus on trace metals, color consistency, and batch reliability. Some applications flag traces of chloride or organics as critical risks—so we know every step we take to minimize these carries an outsized benefit. Years ago, a misplaced drum of sodium carbonate left a taint in one shipment, but that lesson dug deep into our standard operating procedures. Robust segregation, stricter inventory controls, and spot-checks now make it nearly impossible for cross-contamination to reappear. Such stories show that every batch tells its own history, visible to any chemist who takes the time to test thoroughly.

    Comparisons with Other Manufacturers’ Offerings

    Our field visits and sample analyses make one thing clear: not all sodium phenoxide products get equal attention. Price, appearance, and even the ‘neutral chemical’ designation tell half the story. We have encountered batched products elsewhere suffering from poor flow, signs of early oxidation, or batches with out-of-spec sodium content. Our strength comes from refusing to cut corners—a principle reinforced by visits with users who showed us what downstream problems can arise from uncontrolled variance.

    Talking to formulation chemists has shaped our process. Reports of unexpected side reactions pushed us to tighten trace impurity specs. Incidents where competitor samples triggered clogging or dust explosions in high-speed mixing lines provided perspective on why particle homogeneity cannot be a cosmetic issue. Direct customer audits informed our choice to re-invest in packaging and handling lines—a decision that paid off during a recent abnormal monsoon, when the material maintained expected quality while others took production delays.

    Looking Ahead at Market and Application Trends

    Watching global trends in dye and pharmaceutical synthesis, our team tracks every new patent, synthetic method, and project aiming for safer or more selective production. Sodium 4-Chloro-2-Nitrophenoxide shows up repeatedly for its ability to anchor complex functional groups, especially in target-specific synthetic pathways. Its balance—stable under storage yet reactive under controlled conditions—gives it a broad application scope.

    As more users seek cleaner process chemistry and demand traceable, low-residue inputs, we respond by refining purification and drying stages, not just for compliance, but due to evidence written in yield curves and spectral clarity submitted by our industry partners. Over time, routine improvements have made our sodium-based derivative a tool not only for established dye houses and pharmaceutical labs but also for the next generation of innovators exploring greener, more efficient synthesis. Reliable performance translates to fewer failed experiments, higher throughput, and safer workplace conditions, facts reported back by those who depend on every drum shipped from our loading dock.

    The Bottom Line—Expertise Grown from Hands-On Manufacturing

    The story of this compound in our plant extends beyond strictly business. Technical operators, QC chemists, and the logistics crew all bring pieces of the overall performance to the table. We don’t outsource core steps, and we don’t delegate responsibility for purity or documentation. Our users value transparency and consistency rooted in direct manufacturing experience.

    Sodium 4-Chloro-2-Nitrophenoxide, as we deliver it, reflects not only sound chemical engineering but also dozens of cumulative years navigating routine challenges and complex troubleshooting. Its place in applications across fine chemicals, colorants, and research environments traces directly to our boots-on-the-ground understanding of what each customer needs—predictability, traceability, and unwavering quality every time.