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Sodium 4,6-Dinitro-2-Aminophenoxide

    • Product Name Sodium 4,6-Dinitro-2-Aminophenoxide
    • Alias DNPA
    • Einecs 223-245-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    730262

    Chemical_Name Sodium 4,6-Dinitro-2-Aminophenoxide
    Molecular_Formula C6H3N3NaO5
    Molecular_Weight 223.09 g/mol
    Appearance Yellow to orange crystalline powder
    Solubility Soluble in water
    Melting_Point Decomposes above 200°C
    CAS_Number 3930-19-6
    Synonyms Sodium DNAP, Sodium 2-amino-4,6-dinitrophenoxide
    Storage_Conditions Store in a cool, dry place, tightly closed
    Purity Typically ≥98%
    Odor Odorless
    pH_in_Solution Typically alkaline

    As an accredited Sodium 4,6-Dinitro-2-Aminophenoxide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of Sodium 4,6-Dinitro-2-Aminophenoxide, sealed in an amber glass bottle with hazard labeling, stored in a protective carton.
    Shipping Sodium 4,6-Dinitro-2-Aminophenoxide should be shipped in tightly sealed, chemical-resistant containers, kept away from heat, moisture, and incompatible substances. It must be packaged and labeled according to hazardous material regulations, including appropriate hazard class identification, and transported by certified carriers to ensure safety and regulatory compliance during transit.
    Storage Sodium 4,6-Dinitro-2-Aminophenoxide should be stored in a tightly sealed, light-resistant container, in a cool, dry, and well-ventilated area away from heat, moisture, acids, and combustible materials. It should be kept away from sources of ignition and incompatible substances. Clearly label the container, and store it in a designated area for hazardous or reactive chemicals, following all applicable safety regulations.
    Application of Sodium 4,6-Dinitro-2-Aminophenoxide

    Applications of Sodium 4,6-Dinitro-2-Aminophenoxide in Industrial Manufacturing

    Sodium 4,6-Dinitro-2-Aminophenoxide supports specialized manufacturing in several highly regulated sectors. We supply this material directly to advanced downstream operators who depend on consistent input quality for both process efficiency and regulatory compliance.

    1. High-Performance Dyes and Pigments Formulation

    Specialty dye and pigment manufacturers use sodium 4,6-dinitro-2-aminophenoxide as a key intermediate for azo and anthraquinone dye synthesis. Its electron-withdrawing nitro groups offer enhanced chromophore stability and bathochromic shift, crucial for textile dyes with demanding lightfastness requirements. Operators employ it in multi-step coupling reactions under alkaline conditions, optimizing pH for maximum yield while minimizing decomposition. Composite dispersions for fiber and leather coloration rely on precise charge transfer, resulting in stable, intense hues with strong wash resistance. Batch formulation demands accurate weighing, temperature control, and staged addition to ensure uniform color characteristics.

    Industry compliance standards

    • Oeko-Tex Standard 100 for restricted substances in textile dyes
    • REACH Regulation (EC 1907/2006) compliance for dye intermediates
    • ZDHC MRSL for effluent and chemical management
    • ISO 9001 for quality management in pigment production

    Typical usage ratio

    • 2% to 8% by weight of total dye batch, depending on target shade intensity and substrate; formula adjusted for molecular weight and chromophore efficiency

    Downstream process integration

    • Feeds directly into the diazotization and coupling stage during dye synthesis; reactive integration with amines and phenols under batch or continuous process regimes

    Final product types

    • Synthetic textile dyes (direct, acid, disperse)
    • High-stability organic pigments for plastics or inks
    • Leather colorants
    • Technical color solutions for paper and coatings

    2. Pharmaceutical Intermediate Manufacturing

    APIs and advanced intermediates production leverages sodium 4,6-dinitro-2-aminophenoxide in the synthesis of heterocycles and multi-substituted aromatic drug scaffolds. Laboratory and GMP-scale reactors use the compound during nucleophilic aromatic substitution steps for introducing amino, nitro, or alkali-reactive functionalities. Quality assurance ensures strict batch traceability, and real-time monitoring of reaction endpoints safeguards the integrity of downstream synthesis. Only process waters with documented removal of all nitro impurities pass into effluent streams, aligning with strict pharmaceutical discharge requirements.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guide for API synthesis
    • USP-NF monograph compliance for input purity
    • 21 CFR Part 211 (FDA cGMP regulations)
    • European Pharmacopoeia (Ph. Eur.) for quality benchmarks

    Typical usage ratio

    • 0.8 molar equivalent to target active intermediate; reaction stoichiometry varies based on final API structure and yield optimization studies

    Downstream process integration

    • Introduced during aromatic ring functionalization, often via SNAr or condensation steps after protection/deprotection of active groups

    Final product types

    • Non-steroidal anti-inflammatory intermediates
    • Anti-infective chemical scaffolds
    • Fine chemicals for contract pharmaceutical synthesis
    • Specialty reagents for diagnostic kits

    3. Agricultural Fungicide Synthesis

    Agrochemical formulators select sodium 4,6-dinitro-2-aminophenoxide as a precursor for dinitrophenol-based fungicides and seed treatment agents. It enters the synthetic process as an aromatic nitro donor, critical for the manufacture of contact pesticides targeting fungal cell wall biosynthesis. Plants operate under strict containment to address environmental and occupational exposure risks. Analytical monitoring tracks conversion efficiency and impurity levels during reduction and esterification, directly impacting the agronomic safety profile of finished actives. QA teams validate each step through residue analysis to comply with strict Maximum Residue Levels (MRLs) imposed by regional authorities.

    Industry compliance standards

    • FAO/WHO International Code of Conduct on Pesticide Management
    • EPA 40 CFR Part 180 (Tolerance Requirements for Pesticide Chemical Residues)
    • ISO 17025 for in-house analytical validation
    • EU Regulation (EC) 1107/2009 on Plant Protection Products

    Typical usage ratio

    • 5% to 12% as a feedstock portion relative to total active pesticide mass; scaled per batch according to target concentration in formulated product

    Downstream process integration

    • Feeds into initial dinitro compound assembly by aromatic nitration, followed by stepwise reduction and coupling with activating groups for final fungicidal molecule formation

    Final product types

    • Protective agricultural fungicide actives
    • Seed coating agents
    • Crop protection dust formulations
    • Specialized soil amendments

    4. Photographic Chemical Processing

    Photo-industry chemical facilities utilize sodium 4,6-dinitro-2-aminophenoxide for the production of color-forming agents in film and paper processing. It acts as a nucleophilic aromatic base in coupler synthesis and stabilizer systems for silver halide emulsions. Quality teams enforce ultra-low trace contaminant thresholds, as impurities influence silver image density and archival longevity. Precise metering and in-line filtration during coupler synthesis minimize particulate and moisture ingress, which can degrade photographic result consistency across production runs. End users benefit from these tailored inputs through reliable image quality and controlled color balance in final photographic products.

    Industry compliance standards

    • ISO 18902 for chemical stability of imaging materials
    • ANSI IT9.2 for photographic processing chemicals
    • RoHS (for restriction of hazardous substances in photographic equipment)
    • Internal QC benchmarks for Lot-to-Lot consistency

    Typical usage ratio

    • 3% to 6% by solution weight in color coupler and stabilizer chemistry; adjustments depend on photographic emulsion type and target processing environment

    Downstream process integration

    • Added at coupler formulation stage prior to emulsion blending; also employed in stabilization baths within film processing lines

    Final product types

    • Color photographic papers
    • Professional film rolls and technical films
    • Archival-grade imaging emulsions
    • Photographic processing concentrates
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    Certification & Compliance
    More Introduction

    Sodium 4,6-Dinitro-2-Aminophenoxide: Our Approach and Experience as a Manufacturer

    Understanding the Product from the Production Floor

    Sodium 4,6-dinitro-2-aminophenoxide belongs to a class of aromatic chemical intermediates that most chemical producers rarely attempt owing to its unique structural complexity. At our facility, production draws on decades of plant-scale experience and the lessons learned from every batch ever produced. Our day-to-day work with this compound gives us a thorough understanding not just of its chemical formula, but also of the varied demands that our customers bring to each order. We have spent years tuning both our synthesis pathways and our purification protocols for this material—not just to hit purity numbers, but to deliver the steady, reliable quality that advanced manufacturing environments demand.

    Material Characteristics & Specifications That Matter on the Line

    Batch color, crystal morphology, and caking behavior can vary on paper suppliers but only a producer who handles thousands of kilograms can tell you how those fine differences change filterability, dissolution rate, and scale-up risk in real life. Sodium 4,6-dinitro-2-aminophenoxide established itself early as a crucial intermediate for specialized dyes, analytical reagents, and certain crop protection agents. The balance between moisture content and flowability means a lot during downstream blending. Our typical product yields a free-flowing, golden-amber powder, tight moisture control under 0.4%, and very low metal contaminants. By consistently exceeding the assay specification, we reduce the need for downstream adjustments or compensation in formulation.

    Experience-Driven Production Practices

    Through every campaign, we monitor each reaction stage, whether that means calibrating the nitro group addition rate or tweaking the quench temperature to minimize byproduct formation. In some runs, a few degrees can spell the difference between predictable filtration or unexpected downtime. Over the years, our technicians logged hundreds of minor process adjustments—small things like using deionized water for all wash stages, or swapping filter media grades midsummer to reduce exposure to humidity swings. Our team built these changes into our SOPs not for marketing, but to keep every batch on-target before release.

    What Drives Customer Demand for Sodium 4,6-Dinitro-2-Aminophenoxide?

    The compound’s strong electron-withdrawing nitro substituents, paired with the solvating power of the sodium phenoxide group, delivers solubility and reactivity few alternatives match. Dye manufacturers rely on it for high-contrast azo compounds; fine chemical labs value its consistent UV-absorbance characteristics. We’ve fielded plenty of requests for material with tailored particle size, or adjusted sodium content, depending on the customer’s dissolving process or reactor design. Based on feedback from sustainable chemistry partners, our technical staff directed several investments into mother liquor recovery, which lowers waste and increases batch yield—small steps that benefit not just the environment but also the bottom line.

    Built on Benchmarks, Not Promises

    Each year, our R&D chemists release technical bulletins highlighting differences in batch analysis—what subtle shifts in the ortho-nitro substitution mean for uptake in specific dye frameworks, or how a half-percent water content change in humid weather affects downstream blending. These are not just theoretical data points for us; they come from lived experience and side-by-side comparison of hundreds of sample runs, customer reports, and returns. Not all sodium 4,6-dinitro-2-aminophenoxide is equal, and anyone who has tried multiple vendors in scale formulations knows that truth better than a binder of test certificates.

    Regulatory and Quality Demands: More Than Just Checkmarks

    Vendor audits, third-party analyses, and shipment traceability pass through our desks all year. Proper documentation is essential, so we detail provenance of raw materials, batch history, and chain-of-custody data to assure end users of real traceability. Our operators go beyond the minimum, sampling every drum for microtraces of process acids, heavy metals, and unreacted starting materials. Every nonconformance gets logged, and every request for additional data gets addressed by those who personally produced the lot.

    The Right Fit: Differences from Other Nitroaromatic Intermediates

    Sodium 4,6-dinitro-2-aminophenoxide stands apart through a combination of chemical stability and reactivity. Its direct sodium salt form brings higher processing convenience compared to less soluble ammonium or protonated analogs, especially in closed-system aqueous dissolvers. Processors working with less soluble or more air-sensitive intermediates deal with frequent clumping or inconsistent uptake—direct feedback we gain when our tech teams visit plant floors or help troubleshoot customer processes. Where other nitroaromatics bring dusting, thermal instability, or require hazardous solvents to dissolve, this product’s sodium form manages those risks better, provided the operator respects its known hazards and handles per industry-standard protocols.

    Safety and Handling on Our Production Floor

    No nitro compound is entirely without risk. Our in-plant team maintains strict temperature controls, anti-static equipment, and detailed procedure training, as mistakes in this family of chemistry can be unforgiving. We use localized exhaust and continuous air quality monitoring where staff handle open powder transfer. Most lot rejections or process investigations at our plant stem not from the basic chemistry, but from dust control or failings in packaging bulk shipments in humid conditions. This focus on practical handling experience filters down to each shipment; every new customer gets transparent advice on storage, disposal, and transport—not from a form letter, but direct from our technical staff who solve these issues every day.

    Reliable Shipping: Bridging Production and Customer Needs

    Shipping this material domestically or internationally involves a cascade of documentation and transport controls. Each shipment leaves our site with a moisture-vapor-proof, lined drum, as even a day’s delay in the wrong storage environment can trigger caking and loss of flow. Customs requires up-to-date regulatory paperwork, while buyers expect on-spec product, undamaged and fresh. By investing in digital tracking, climate-control storage, and durable packaging, our logistics crew closes the loop between batch signoff and end-user satisfaction. We don’t cut corners, because we know the downstream impact of even small handling mistakes.

    Continuous Improvement: Learning with Each Order

    New production methods, novel applications, and market requirements change year to year. A decade ago, few outside Europe sought lower residual nitrophenol; now, tighter controls and green chemistry requirements challenge us to push our limits. Each customer request for finetuned purity or alternative packing formats starts a back-and-forth with our production team and chemists. Recent years brought pilot plant modifications—high-vacuum drying, low-dust powder transfer, and improved analytical feedback loops—which grew directly from user feedback and operator experience.

    Comparing with Other Approaches

    Some buyers look at similar aminophenoxide intermediates from other manufacturing bases, comparing results side-by-side. What they often notice: sodium 4,6-dinitro-2-aminophenoxide yields higher solubility in water-based systems, handles easier at ambient conditions, and integrates into existing dye reaction workflows with fewer stoppages. Others test the ammonium salt or the free acid form and report more clogging, slower reactions, or color instability. Every user may have a slightly different formulation or regulatory hurdle, but practical outcomes—consistent performance, speed of dissolution, and stable blending—separate products that come from a careful production culture versus bulk trading sources.

    Seeking Solutions to Common Challenges

    Scaling up production without increasing waste, improving shipment shelf life, and handling regulatory changes make up the core of our daily work. We have invested in closed-loop filtration to cut water use, modular packaging lines for prompt switching between drum sizes, and expanded our analytical toolbox to meet more precise impurity requests. When material doesn’t behave as expected in a user’s plant, our staff dig into plant-scale simulations and offer practical advice, rather than generic lab protocols that miss the real variables at work.

    Supporting Customers Beyond the Sale

    Customers often call or write for advice on how to dissipate clumping in humid regions or reduce unwanted color bleed during secondary reactions. Our technical staff don’t just recite product brochures; they draw from years of experience producing, storing, and handling this family of chemicals under similar constraints. We keep the lines open for feedback—and we use it to shape the next production run.

    Looking Ahead: Sustaining Responsible Production

    The market expects better every year. Downstream buyers want full documentation, more sustainable sourcing, and tighter impurity controls. Our staff engages in continuous skills training and cross-checks each other’s work, knowing that true improvements flow from people, not just machines or data collection. We maintain partnerships with local suppliers for starting materials and invest in long-term process safety reviews, understanding that good production means anticipating not only current demand but also the regulatory, safety, and sustainability challenges of the years to come.

    Why Experience Still Matters

    Any producer can mimic standard tests and data. Yet, it takes years in the field—and more than a few mistakes—to tune in the subtle factors that spell the difference between a trouble-free run and an unexpected process bottleneck downstream. Sodium 4,6-dinitro-2-aminophenoxide continues to anchor itself as a reliable building block across industries because manufacturing it right demands more than theory; it asks for patient refinement, operator know-how, and a willingness to keep learning batch by batch.

    Our Perspective as a True Manufacturer

    We ship each container with the confidence born not from reselling someone else’s output, but from crafting each lot from start to finish. Only those with direct control over the entire process—from sourcing starting materials to managing final shipment—can offer the kind of reliability that busy production plants and R&D teams need. Long-term customer relationships arise not from the lowest price, but from a consistent track record of performance, candid technical support, and the willingness to collaborate whenever new challenges crop up. With sodium 4,6-dinitro-2-aminophenoxide, our job isn’t finished at the loading dock; it extends to every end user who counts on reliable inputs—for today and for the next decade of innovation.