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Sodium 2,4-Dinitrophenoxide

    • Product Name Sodium 2,4-Dinitrophenoxide
    • Alias DNPA
    • Einecs 210-058-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    937240

    chemical_name Sodium 2,4-Dinitrophenoxide
    molecular_formula C6H3N2NaO5
    molar_mass 206.08 g/mol
    appearance Yellow to orange crystalline solid
    solubility_in_water Soluble
    melting_point Decomposes before melting
    cas_number 38379-98-5
    pubchem_cid 6327090
    storage_conditions Store in a cool, dry place; keep container tightly closed

    As an accredited Sodium 2,4-Dinitrophenoxide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g amber glass bottle with screw cap, labeled "Sodium 2,4-Dinitrophenoxide", hazardous warning symbols, and handling precautions.
    Shipping **Shipping Description for Sodium 2,4-Dinitrophenoxide:** Ship in tightly sealed containers, protected from moisture and incompatible materials. Clearly label as hazardous; handle in accordance with regulations for toxic, oxidizing, and potentially explosive substances. Use secondary containment and proper cushioning. Transport under controlled temperature and away from direct sunlight or sources of ignition, following all applicable local and international shipping requirements.
    Storage **Sodium 2,4-Dinitrophenoxide** should be stored in a tightly sealed container, away from moisture, direct sunlight, and sources of heat or ignition. Keep in a cool, dry, well-ventilated area, segregated from acids and oxidizing agents. Clearly label the storage container, and follow all relevant safety regulations and material safety data sheets (MSDS) for handling and storage procedures.
    Application of Sodium 2,4-Dinitrophenoxide

    Applications of Sodium 2,4-Dinitrophenoxide in Industrial Manufacturing

    Sodium 2,4-Dinitrophenoxide serves as a key intermediate in several industrial sectors, supporting diverse chemical synthesis pathways from active pharmaceutical ingredients to high-performance dyes. As the original manufacturer, we understand the strict technical, regulatory, and formulation demands in each application channel and provide material grades tailored to each downstream requirement.

    1. Pharmaceutical Intermediate Synthesis

    This raw material plays a crucial role in the multi-step synthesis of certain active pharmaceutical ingredients (APIs), especially in the field of anti-tuberculosis and anti-parasitic drug production. It undergoes nucleophilic substitution, providing a nitrophenolic moiety essential for creating complex molecular scaffolds. Manufacturers integrate it during early to mid-stage API development to achieve targeted substitution patterns, especially where strong electron-withdrawing groups are required on benzene rings.

    Industry compliance standards

    • Good Manufacturing Practice (GMP) per ICH Q7
    • European Pharmacopoeia (Ph. Eur.) specification for intermediates
    • US FDA 21 CFR Part 211 compliance for cGMP
    • ICH Q3A/B for impurity profile management

    Typical usage ratio

    • Employed at 0.2–0.4 molar equivalents relative to the primary amine or halide used in the subsequent step; adjusted based on competitive side reactions and targeted yield optimization.

    Downstream process integration

    • Charged directly into multi-stage batch reactors during nitration or coupling steps; typically neutralized post-reaction and removed by aqueous workup or phase separation prior to isolation of the API intermediate.

    Final product types

    • Anti-tuberculosis APIs (e.g., dapsone and related analogs)
    • Anti-parasitic API intermediates (e.g., for suramin synthesis)
    • Precursors for veterinary medicines in regulated markets
    • Specialty intermediates supplied for custom API contract manufacturing

    2. Agrochemical Active Ingredient Manufacturing

    The compound is used in the formulation of select herbicidal and insecticidal actives, especially where ring nitration and phenoxide functionalities enhance biological activity. Downstream producers introduce it as a building block for specific dinitrophenol-based agrochemicals, ensuring appropriate substitution and yield during synthesis, particularly in controlled batch production for high-value crop protection agents.

    Industry compliance standards

    • FAO/WHO specifications for pesticide technical grade materials
    • REACH registration for European supply chains
    • OECD guidelines for chemical manufacturing safety and intermediate handling
    • China National Standards (GB) for pesticide raw materials

    Typical usage ratio

    • Ranges between 5–10% by weight in bulk synthesis for actives, modulated according to target molecule complexity and crop selectivity requirements; fine-tuned during process validation trials to limit by-product formation.

    Downstream process integration

    • Incorporated during early derivatization stages of active ingredient synthesis; combined with other substituted phenols and processed in solvent-mediated coupling, with subsequent quenching and isolation for formulation.

    Final product types

    • Dinitrophenol-derived herbicides
    • Specific crop protection agents for resistant weed management
    • Seed treatment active bases
    • Intermediate inputs for custom pesticide formulation contractors

    3. Azo and Anthraquinone Dye Manufacturing

    Sodium 2,4-Dinitrophenoxide functions as a primary coupling component in azo dye synthesis and as a modifying agent in anthraquinone dye technology. Dye producers employ it to introduce strong chromophoric groups and maintain bath stability during diazotization and coupling reactions. Its high electron-withdrawing capability allows precise tuning of wavelength absorption and colorfastness characteristics.

    Industry compliance standards

    • OEKO-TEX Standard 100 for textile chemical input safety
    • ZDHC MRSL v3.1 for restricted hazardous chemicals
    • REACH Annex XVII compliance for dye intermediates
    • ISO 105-C06 and ISO 105-E01 for colorfastness testing

    Typical usage ratio

    • Utilized at 1–6% of the total dye formula mass, adjusted by chromophore type and application substrate (cellulosic vs. synthetic fibers); bench-tested to balance intensity and process yield.

    Downstream process integration

    • Dosed into coupling reactors during primary chromogen development; neutralized and purified post-reaction with filtration before blending into commercial dye stocks.

    Final product types

    • Bright yellow azo dyes for synthetic fiber applications
    • Modified anthraquinone dyes with enhanced lightfastness
    • Textile batch dyes for active sportswear manufacturing
    • Technical colorants for plastic and coating industry dispersions

    4. Explosives and Energetic Materials Synthesis

    The compound is a specialized precursor in the controlled production of certain energetic materials, supporting the synthesis of dinitrophenol-based explosives. Its reactive nitrophenolate structure enables efficient conversion in multi-step nitration and condensation sequences. Manufacturers in this sector emphasize traceability and reagent purity during large-scale synthesis for safety-critical applications.

    Industry compliance standards

    • UN Recommendations on the Transport of Dangerous Goods
    • ITAR (International Traffic in Arms Regulations) for US-origin specialty chemicals
    • EU Regulation (EC) No 1907/2006 (REACH) for manufacture and handling
    • ISO 17025 for laboratory quality control on batch validation

    Typical usage ratio

    • Applied at 7–12% by mass in the energetic precursor cocktail, precisely weighed to balance reactivity and final yield; adjusted in response to end-use requirements and stability benchmarks.

    Downstream process integration

    • Added in stepwise fashion to dedicated reactors under rigorously controlled temperature and agitation profiles, followed by staged nitration; intermediate workups conducted for batch purity assessment.

    Final product types

    • Dinitrophenol-class commercial explosives
    • Specialty initiators for mining and construction blasting agents
    • Laboratory energetic materials for testing protocols
    • Defense sector intermediate energetic chemicals

    5. Rubber Chemical and Vulcanization Accelerator Production

    Within specialty rubber compounding, this material acts as a precursor to certain vulcanization accelerators and stabilizers, facilitating effective sulfur cross-linking. Industry users blend it in specific formulations to improve curing times and enhance final mechanical properties, particularly in applications where high-temperature performance and chemical resistance must meet demanding standards.

    Industry compliance standards

    • ASTM D2000 for rubber material specifications
    • ISO 9001:2015 for process quality control in specialty compounds
    • REACH notification for chemical substances in EU manufacturing
    • OSHA 29 CFR 1910.1200 for workplace chemical safety

    Typical usage ratio

    • Introduced at 0.5–2.5% by total rubber batch weight, with precise measurement based on masterbatch viscosity and final application (automotive, industrial, or consumer products).

    Downstream process integration

    • Premixed with other accelerator components and process oils prior to polymer addition, followed by compounding and final mold curing under controlled temperature and pressure regimes.

    Final product types

    • Sulfur crosslinking accelerators for tire manufacturing
    • Chemical stabilizers for high-performance mechanical rubber goods
    • Sealing and gasket compounds for industrial equipment
    • Anti-aging additive components in elastomer masterbatches
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    Certification & Compliance
    More Introduction

    Sodium 2,4-Dinitrophenoxide – A Practical Choice Backed by Real Experience

    Understanding Our Approach to Manufacturing

    Over decades in chemical manufacturing, we have worked to refine every aspect of the production process for specialty intermediates. Sodium 2,4-Dinitrophenoxide remains a clear example of a product that rewards careful process control, purity management, and practical thinking at the reactor and purification stages. Most applications in dyes, pharmaceuticals, and advanced synthesis depend not only on consistent product but also on transparency and technical follow-up by the manufacturer. Batch traceability, clean supply chains, and adaptable specifications set the stage for reliability in critical downstream reactions.

    Product Introduction: Direct from the Production Floor

    We produce Sodium 2,4-Dinitrophenoxide under tightly monitored conditions, using proven raw materials and closed system handling. Chemists and operators pay close attention to reaction temperature, pressure, and mixing—not only to achieve the right conversion and yield but to prevent secondary impurities that could carry over into your process. The final material appears as a yellow to orange crystalline solid, with distinct solubility in water and many polar organic solvents. By working so closely with the entire process, we maintain a product that meets rigorous expectations in coloring, purity, and consistent bulk density.

    Model and Physical Specifications: Real-World Production Standards

    Each lot comes with batch-level data and inspection notes straight from the plant. Assay by titration and HPLC averages above 99%, an achievable level because we invest effort at the purification and filtration steps. The sodium salt form supports reliable handling—it resists caking during shipment and storage. Particle size control matters for some users, so we routinely monitor and sieve to limit dusting or oversized material that can affect metering. Moisture levels are held in check using vacuum drying and moisture-tight packaging. Typical color index reflects the crystalline structure and low byproduct residue. While certain customers may request finer or coarser grades for special activities, our standard product walks a fine line between ease of handling and high reactivity, as shown in years of feedback from our partners.

    Applications: Lessons Learned from Daily Use

    Most of our sodium 2,4-dinitrophenoxide enters the synthesis of dyes, especially azo and anthraquinone classes, where its reactivity supports coupling with aromatic amines or other activated substrates. Users in specialty pigments value predictable performance under scale-up—yields remain steady, color formation tracks closely with theoretical values, and the isolation of the end product requires less washing when upstream purity is high.

    Some R&D and pharmaceutical customers run narrower campaigns, where the main concern shifts to minimizing even trace contaminants that confound downstream purification. Drawing on these user requests, we have further reduced heavy metals and organic byproduct carryover, measured at the ppm level. The sodium base also makes this molecule a strong candidate for deprotonation and nucleophilic substitutions, especially for introducing aryl functionalities in specialized building blocks. In these runs, uncontrolled alkali or off-spec byproducts in alternative materials result in stuck reactions or cloudy filtrates—a headache that quickly turns into costly downtime, as we have seen through troubleshooting efforts with longtime clients.

    Other applications turn up in agrochemical research, where fine control over reaction rates and isolation means the chemist avoids waste and unnecessary rinsing stages. Analytical labs sometimes ask for the highest possible clarity in NMR or MS, an area where lower-purity or traded material leads to inconsistent results between runs. Details like bulk density and flowability might sound ordinary but become critical any time an operation automates dosing or tries to scale experimental results.

    Reliability: What It Really Means for Users

    Many producers offer nominal 98-99% pure sodium 2,4-dinitrophenoxide, but lack real-world controls on the physical attributes and trace components. Purity by itself does not capture batch-to-batch variability. Material from different sources may appear identical but lead to vastly different color strengths, overnight crystallization in solution, or odd odors in the finished product. Old or poorly stabilized stock, sometimes encountered from resellers, can clump, degrade, or exhibit off-color—especially when bags are stored with ambient moisture or in sunlight.

    We ship from fresh lots, using low-permeability bags and tamper-resistant outer drums to sidestep these risks. Internal stability checks verify that the main features—reactivity, color, solubility—hold steady for well over twelve months from production, avoiding last-minute surprises at the reactor. Any deviations in color, trace nitrogen content, or physical properties are pulled for reevaluation, ensuring the material you receive fits the performance you expect.

    Comparisons with Similar Materials: Insights from Experience

    Buyers occasionally ask about pricing or practical differences between this sodium salt and raw 2,4-dinitrophenol or similar dinitro-compounds (potassium analogs, for instance). Feedback from plants and development labs paints a clear picture. The sodium salt flows better, dissolves faster, and produces less process waste than direct use of the neutral phenol. Downstream, the byproducts from neutralization using unsupported bases or cheap alternatives tend to persist through extraction steps. They can also damage equipment over time, judge by the scale deposits and filter fouling we have dissected during troubleshooting calls.

    The sodium salt arrives ready to use, with defined stoichiometry for reactions in both batch and continuous setups. This reduces the guesswork that comes from adjusting for inconsistent neutralization, and sidesteps the introduction of excess moisture. While potassium and ammonium salts may serve for niche reactions, their flow and reactivity profiles force changes to established SOPs. Moving from the free acid, or between salt types, invites new risks—formation of less soluble forms, off-tints in final colors, variable coupling yields, and filter blockages. Over time, process chemists prefer the trusted baseline that comes from using well-controlled sodium 2,4-dinitrophenoxide lot after lot.

    Real-World Problems: Preventing Process Downtime

    A lesson that stands out over years: overlooked details in material supply show up long before the product ships to customers. Inconsistency at the supplier or trader level often translates into erratic melting points, color drifts, or problems with filtration. Labs analyzing failed or slow reactions have told us later that switching back to well-made sodium 2,4-dinitrophenoxide stabilized their entire process.

    Even newer customers notice impacts on material handling, such as dust generation during transfer or caking in automated dispensers. Our team regularly reviews feedback from operators and blends that experience into both the production level and packaging. Choosing the right moisture barrier, fixing weights to fit user silos, and monitoring bulk density in-process all flow from this feedback loop. What once might have required expense on new equipment now finds a simpler solution at the material handling level, improving both productivity and operator safety.

    Quality Control and Supply Chain Transparency

    We produce and test under a framework of fully traceable batch records and retained samples. Every shipment draws on in-house QC—titration, UV-Vis and HPLC analysis, moisture checks—to spot deviations before any invoice is raised. Years of robust internal review support why customers report few, if any, plant-level shutdowns due to material issues. Regular participation in supplier audits and information sharing helps keep our standards both practical and up to date.

    Nonconformance triggers immediate internal review and, if needed, material recall. We track feedback on everything from shipment times to post-delivery usage, discovering how seemingly minor details—color shade, packaging thickness, change in shipment interval—affect plant routine. By addressing these pain points head-on, we help partners avoid costly errors and keep continuous operation in sight.

    Environmental and Regulatory Considerations

    Sodium 2,4-dinitrophenoxide, like its downstream uses, draws regulatory focus because of its potential roles in chemical synthesis and colorant manufacture. We have invested significantly to minimize the waste and uncontrolled emissions from our production. Closed filtration, solvent recovery, and on-site treatment back up our longstanding push for compliance. Waste streams undergo neutralization, monitored for residual nitrophenols and sodium. Direct reduction in our own discharge levels translates to easier permitting for your facility and fewer distractions from your main business.

    Periodic review by environmental and occupational safety teams helps set priorities. Plant layout and waste handling standards reflect the input from shift operators and safety officers. Real-time monitoring allows us to act quickly if an anomaly occurs, preventing downstream users from receiving affected batches. Compliant reporting extends to product—for example, we provide reference documentation and support to help users speed up their own chemical safety and environmental reporting.

    Addressing Unexpected Issues: Rooted in Day-to-Day Experience

    We notice some recurring issues in the field, often linked to vendor variability or packaging. Many times, clumping during rainy seasons or transit in humid coastal areas causes processing headaches. We build in moisture-absorbing liners based on feedback and track supply chain climate patterns to preempt problems. Color shifts, often from exposure to light or oxidation, come up most frequently when customers hold reserves or partial bags in uncontrolled storage. Internal packaging and labeling helps keep all shipments protected until planned use.

    Most sourcing errors happen not at ordering but through substitution with similarly named but lower-quality dinitro compounds. Not every supplier delivers proven material. Customers facing low coupling yields or persistent equipment fouling almost always trace it back to under-characterized, off-grade, or blended incoming lots. Having watched these supply chain issues escalate in real time, we keep extra focus on process authentication—down to the documentation in each shipment.

    Ongoing Improvements and Customer Collaboration

    Lessons from customer runs and internal trials push us to refine our product each year. Tightening the particle size range, improving packaging convenience, and upgrading batch reporting have emerged through back-and-forth with industry partners. Each new change runs the full cycle from production trial to full-scale shipment, with a focus on operator ease, traceability, and end-use reliability. Our customers’ questions—why did filtration slow on rainy days, should the material cake in older drums, what’s changed between last year’s and this year’s shipment—fuel the cycle of improvements.

    Even minor requests, like premeasured drums for in-line feeders or special lot certification for regulated exports, arise from direct factory-lab communication. Long-term clients help us shape next-generation product lines by reporting on pilot-scale setbacks and sharing feedback about downstream purification or analytic consistency. Instead of top-down changes, we work these real details into each year’s production planning.

    Industry Perspective: What Sets Manufacturer-Backed Supply Apart

    Many of our customers started off sourcing through traders or distributors before reaching out directly. Among the challenges: delayed communication during quality incidents, slow response to specification questions, lack of real accountability for off-spec batches. Working manufacturer-direct fixes these issues because it ties technical support, production, and delivery into a single supply chain. If something deviates or if a batch does not perform, the questions go straight to our lab or plant—where solutions can be implemented in real time.

    Long-term relationships have shown us that consistent feedback, training, and even remote audits lift the entire quality chain. Process engineers know they are not just ordering a commodity but a material built on tested protocols and adapted to meet both regulatory inspection and evolving plant practice. For new users, the risk drops dramatically—no more struggling to interpret vague third-party certificates, or chasing accountability as deadlines loom.

    Looking Ahead: Adapting to Change Without Compromising Reliability

    Chemical manufacturing never sits still. Through supply shocks, regulatory updates, and new applications, we stay close to the real needs of our sodium 2,4-dinitrophenoxide users. Whether a small R&D trial seeks unusual solubility or a full-scale pigment plant demands consistent material every quarter, our focus stays on steady improvements without forgetting what has worked well for decades. It’s not uncommon for us to revisit even the basics—analyzing how subtle changes in raw inputs or utilities affect the delicate balance of downstream production. Each adjustment, no matter how technical, is rooted in lessons picked up from shop floor troubleshooting or hands-on client labs.

    Professional pride and shared success drive us to keep pushing for better handling, higher purity, safer processes, and more transparent communication. From packaging choices that cut dust and waste, to ongoing training for plant staff and open feedback channels, the partnership with our customers stretches well beyond a purchase order. Reliable sodium 2,4-dinitrophenoxide comes from a manufacturer who knows its strengths, solves its limitations, and listens closely to the people who use it every day.