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Paraldehyde

    • Product Name Paraldehyde
    • Alias Ethanal trimer
    • Einecs 204-704-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    176903

    Cas Number 123-63-7
    Molecular Formula C6H12O3
    Molecular Weight 132.16 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Aromatic, ether-like
    Boiling Point 124°C (255°F)
    Melting Point -51°C (-60°F)
    Density 0.997 g/cm³ at 20°C
    Solubility In Water Slightly soluble
    Flash Point 43°C (109°F)
    Vapor Pressure 17 mmHg at 20°C
    Refractive Index 1.405 at 20°C

    As an accredited Paraldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500 mL amber glass bottle, tightly sealed, with chemical hazard labeling and "Paraldehyde" printed clearly on the outer packaging.
    Shipping Paraldehyde is shipped in tightly sealed, corrosion-resistant containers, typically steel drums or glass bottles, due to its volatile, flammable, and moisture-sensitive nature. It is transported under cool conditions, with proper labeling as a hazardous material. Care is taken to avoid exposure to heat, light, and strong acids during transit.
    Storage Paraldehyde should be stored in tightly closed, **light-resistant, glass containers** away from heat, sunlight, and sources of ignition, as it is volatile and flammable. Containers must be kept upright to prevent leakage, in a cool, well-ventilated area, separate from acids, oxidizers, and alkalies. Prolonged contact with air should be avoided to prevent decomposition.
    Application of Paraldehyde

    Applications of Paraldehyde in Industrial Manufacturing

    As an established producer of paraldehyde with direct engagement in industrial process optimization and stringent quality management, we supply material to a select range of sectors where regulatory-compliant use determines sustainable value. Below, we profile genuine industrial scenarios, focusing on how paraldehyde is integrated in downstream manufacturing and what standards, dosing, processing, and product typologies are pivotal in each field.

    1. Sedative Formulations in Pharmaceutical Synthesis

    Pharmaceutical plants utilize paraldehyde during the synthesis of sedative agents, mainly where oral or parenteral sedative formulations demand batch controls for purity and low residual impurities. Material enters the process as a reactant or a processing aid, subject to strict GMP validation and documentation. Application specialists determine the addition based on target pharmacological profiles and regulatory maximum residue limits. The substance is removed or converted downstream depending on route of administration, with quality checkpoints at each process stage to meet pharmacopeial monograph specifications.

    Industry compliance standards

    • European Pharmacopoeia (Ph. Eur.) monograph requirements
    • United States Pharmacopeia (USP)
    • FDA cGMP for APIs (21 CFR Parts 210/211)
    • WHO Good Manufacturing Practice

    Typical usage ratio

    • Reaction or processing: typically 0.5–2.5% by mass of batch, adjusted according to target molecule yield and downstream removal via distillation or neutralization

    Downstream process integration

    • Charged in initial condensation step for sedative active ingredient synthesis
    • Removed as a residual solvent in purification or intermediate isolation
    • Closed-system transfer and monitored vapor control due to volatility

    Final product types

    • Hospital sedative ampoules (injectable preparations)
    • Oral hypnotic syrups
    • Tableted mild tranquilizers (with paraldehyde removed post-reaction)

    2. Intermediate for Fine Chemicals and Agrochemical Synthesis

    In fine chemical and agrochemical manufacturing, paraldehyde functions as a key aldehyde source or as a protective agent in complex multi-stage syntheses. R&D and production teams rely on its reactivity in condensation or alkylation steps, where process efficiency and operator safety are balanced by precise in-line controls. Manufacturer QC confirms trace residuals to satisfy both internal QA and customer audit requirements in finished intermediates used downstream by crop protection active producers.

    Industry compliance standards

    • REACH (EC No. 1907/2006) chemical safety assessment
    • ISO 9001 quality management system
    • National Pollutant Release Inventory (as hazardous chemical)
    • Guidelines for the Safe Use of Chemicals in Industry (country specific)

    Typical usage ratio

    • As reactant or protecting group: 1–5% w/w of total reactant mass, fine-tuned based on crop protection molecule synthesis route

    Downstream process integration

    • Added to batch at key intermediate step (e.g., acetalization)
    • Removed or hydrolyzed before crystallization or purification
    • Use of organo-catalysis or controlled temperature jacket reactors

    Final product types

    • Aldehyde-derivative fungicide intermediates
    • Herbicide precursor compounds
    • Pesticide formulation bases (before formulation dilution)

    3. Polymer Processing and Catalysis Aid in Resin Manufacturing

    Commercial resin plants adopt paraldehyde as a polymerization catalyst or chain-modifier in the production of select urea-formaldehyde and phenolic resins. Addition timing and metering are controlled automatically to maximize conversion and minimize color body formation. Safety protocols oversee vapor recovery, especially for closed-vessel polymerizations, while QC analysts verify absence of unwanted oligomers and unreacted species in the final resin matrix, satisfying major safety and quality guidelines.

    Industry compliance standards

    • ASTM D7473 - Standard Guide for Testing Polymeric Materials
    • ISO 14001 Environmental Management System (effluent handling)
    • OSHA Process Safety Management (29 CFR 1910.119)
    • Chemical Control Law (CCL) regional compliance for polymer additives

    Typical usage ratio

    • Polymerization stage: 0.15–0.8% of total monomer input, adjusted for desired resin molecular weight distribution

    Downstream process integration

    • Dosed at initial charge for catalytic initiation in reactor
    • Monitored by molecular weight and viscosity endpoint measurement
    • Residual traces removed in vacuum drying or devolatilization

    Final product types

    • Electrical-grade encapsulation resins
    • Adhesive resins for plywood and panel manufacturing
    • Molding compounds for automotive or appliance components

    4. Laboratory and Analytical Use as Derivatization Reagent

    Certified laboratories and analytical reagent suppliers incorporate paraldehyde in chemical derivatization protocols, particularly in sample preparation for gas chromatography or aldehyde determination by spectrophotometry. Technicians calibrate dosing based on analyte concentration and robustness of detection method, and maintain rigorous chain-of-custody and instrument calibration traceability for accreditation consistency.

    Industry compliance standards

    • ISO/IEC 17025 Laboratory Competence
    • AOAC International Official Methods
    • EPA Method 8315A (Aldehydes by HPLC)
    • Internal laboratory SOPs for hazardous chemical handling

    Typical usage ratio

    • For derivatization: 0.1–1.5% (v/v) of total sample/solvent volume, scaled by detection limits and analyte abundance

    Downstream process integration

    • Added during sample prep prior to analytical run
    • Mixing, standing, and extraction steps prior to injection or assay
    • Handled under fume hood or closed micro-vessels

    Final product types

    • Certified analytical test kits (for formaldehyde/acetaldehyde)
    • Standard reference materials
    • Pre-treated environmental or food testing cartridges

    5. Disinfectant and Preservative Formulation Component

    Select industrial disinfectant and preservative manufacturers apply paraldehyde in formulation blends targeting surfaces or packaged medical instrument preservation, leveraging its controlled volatility. Dosing is designed with respect to local regulatory restrictions, biocidal efficacy studies, and vapor exposure control. Final blending emphasizes even distribution and shelf life stability, and QA labs screen each production lot for purity and label accuracy to meet end-user and legislative demands.

    Industry compliance standards

    • EU Biocidal Products Regulation (BPR, Regulation (EU) 528/2012)
    • U.S. EPA Office of Pesticide Programs (OPP) registration
    • EN 14885 for antimicrobial efficacy claims
    • CLP Regulation (EC No 1272/2008) for detergent labeling

    Typical usage ratio

    • In finished disinfectant blend: typically 0.5–3% by volume; formulation scientists adjust based on surface type and allowable exposure limits

    Downstream process integration

    • Added to base liquid during blending in stainless tank with controlled agitation
    • Consistency monitored throughout with inline viscosity and pH sensors
    • Packaged in sealed containers to limit vapor loss

    Final product types

    • Instrument soaking solutions for hospital and dental use
    • Industrial-grade surface wipes
    • Room disinfection aerosols and sprays
    Free Quote

    Competitive Paraldehyde prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

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    Certification & Compliance
    More Introduction

    Paraldehyde: From Our Factory Floor to Your Process

    Manufacturers Who Know Paraldehyde

    Walking through the plant, the distinct, penetrating scent of Paraldehyde always stands out, unmistakable even when the wind shifts through chemicals far more pungent. Old-timers who worked these reactors decades before us knew it as a mainstay—not just something stashed away for emergencies, but a staple. Producing Paraldehyde isn’t showy work, but it’s honest and, in our line, reliable. The process grew out of necessity, not just for a cleaner alternative to more volatile aldehyde derivatives, but for the consistency batch after batch demanded by critical downstream users.

    Our production lines aren’t cobbled together operations; reactors built for pressure and heat cycling, handled by operators who’ve seen what happens if a batch runs too long or cools too quickly. Every charge has to hydrate smoothly; every fraction run needs that careful eye. The know-how to judge a product before it ever hits a gas chromatograph matters. This is not just chemistry. This is practice, patience, observation—the sorts of values that can’t get written into a spec sheet.

    What Paraldehyde Brings to Industry

    We produce Paraldehyde with acute attention to purity and water control. This approach traces back generations, because trace moisture or residual formaldehyde stings quality right where it hurts reliability. Paraldehyde, with its molecular formula C6H12O3, avoids many problems that crop up with open-chain aldehydes—it’s less reactive, stores better, and works longer without unexpected degradation. Our reactors turn out Paraldehyde in liquid form, clear and mobile, with a subtle oily sheen when poured. We keep chromatographic purity above 98.5%. Almost nothing else proves as manageable for long-term storage under the right conditions.

    Many buyers recognize Paraldehyde from its century-long use in pharmaceuticals and clinical settings, but our experience tells a broader story. The real volume gets pulled into chemical intermediates, solvent blends, and specialty polymerizations. For folks unsure why chemists reach for Paraldehyde instead of straight acetaldehyde or other aldehyde-based products, it almost always comes down to stability and storage. Acetaldehyde likes to polymerize, lose potency, and, frankly, make a mess. We see fewer returns, less waste, and a lot less grumbling from plant managers using Paraldehyde as an intermediate. It forms stable adducts, doesn’t evaporate off at the first sign of summer, and blends well in multi-step syntheses where timing can slip hours or days.

    Beyond the Product: What Specification Really Means

    Day-to-day, most specifications come down to how easily the end user can work with the product. It’s one thing to write “water content below 0.1%,” but it’s quite another to see what happens when an off-spec drum gums up a dosing line. We monitor water, acid number, and aldehyde residue on every lot. Each specification, whether on residual acidity or flash point, emerged out of real problems—polymer plants where Paraldehyde kicked off unwanted chain reactions, labs where purity swings led to variable yields, or hospitals that needed consistent results dose after dose. Our numbers aren’t bureaucratic. They solve problems.

    The regulatory environment rewards thorough documentation, and we’ve learned to keep analytical records open for review. Nobody likes a surprise. Soils and solvents differ plant to plant, but what matters most stays constant: operators need the same results in February as they do in July. In our own labs we verify with Karl Fischer for water, titrimetry for acidity, and gas chromatography for organics. If our product lands out of spec, we reprocess—the only way to keep a name worth trusting.

    On the Subject of Alternatives

    On paper, there are substitutes for Paraldehyde. Markets in North America and Asia sometimes prefer glyoxal or other acetals, mainly because they sound newer or because distributors build a pitch around a supposed advantage. The reality shows up on the shop floor. Glyoxal turns nasty with moisture, giving sticky problems in dosing systems and higher risk of off-gassing. Some solvents promise higher reactivity but seldom deliver the same shelf life or temperature resilience.

    Customers in pharma and medical supply want what works, not a flyer on a trade show sample. The stability of Paraldehyde continues to give it an edge when handling and storage are non-negotiable. In the 1960s and 70s, attempts to retool lines toward modern imidazoles and new acetate blends fizzled out for one consistent reason: they broke down, contaminated valves, and required costly downtime.

    Engineered for the Real World

    We built our Paraldehyde processes against the headaches of actual users: fouling, unpredictable reactivity, shelf life uncertainty, worker comfort, and the relentless quest for uptime. Our plant has run the same core synthesis route for decades while making small, proven tweaks based on failures no one ever wants to admit—every chemical producer has inventory lost to runaway exotherms or tanks breached by vacuum that never should have happened. We treat these as learning opportunities: automation for adding acid catalyst, dual containment for intermediate transfer, and disciplined thermal regulation.

    Our packaging team fills from dedicated stainless steel lines, flushes drums with nitrogen, and seals every cap with a tamper-evident band. Customers don’t see the small adjustments—but only because they don’t have to. Deliveries show up on time, clear, uncontaminated, on-spec every time because we build to withstand the noise of real supply chains.

    Product Details: More than Numbers

    Paraldehyde’s physical profile supports its appeal—a boiling point of roughly 124°C, immiscibility with water, moderate vapor pressure, and good compatibility with metals used in safe handling systems. Tanks last longer, lines need less cleaning, and fill crews face few surprises. We manufacture to a purity above 98.5% by GC, acid content consistently under 0.005%, and guarantee drums free from overexposure to heat cycles that break stability. Volatility sits at a sweet spot: sufficient to meter reliably but nowhere near the explosive risk profile of all-too-familiar aldehydes.

    End users rarely sweat the numbers unless forced to, but those lost hours fixing clogged jets or unscheduled plant shutdowns make details matter. Paraldehyde holds together within closed systems, maintains reactivity for weeks in storage, and resists degradation under ordinary plant or hospital storage. We don’t load our specs with buzzwords or empty promises; every line was learned at our own expense, in lost batches or customer complaints.

    Uses Shaped by Decades of Demand

    Our largest volumes exit the plant in drums destined for use as solvents, intermediates, and, in more regulated countries, as sedatives and anticonvulsants under controlled settings. Hospitals and clinics recognize Paraldehyde for its rapid onset and direct elimination—less concern over downstream metabolites, rare in medication but valuable in emergencies. Our feedback shows that even as newer sedatives hit the market, nothing displaces Paraldehyde for emergency convulsion care where other therapies fall short.

    In industry, Paraldehyde always turns up in odd places. Resin manufacturers prize its stability—not reactive enough to spoil a batch at room temperature, yet available to react cleanly when catalyzed. Certain specialty rubber compounds still rely on Paraldehyde as a controlled donor of acetaldehyde under heat. We ship to perfumers blending aldehyde-rich fragrances because the stuff works in small quantities without overloading a volatile blend. Academic and specialty chemists know our brand, not because of slick advertising, but because the product works every time the process calls for it. Paraldehyde underwrites consistency-after-consistency: that is the backbone of our business.

    Why We Stick With Paraldehyde

    It’s easy to overthink product selection with so many alternatives thrown at purchasing teams. Many of our clients switched away, curious if cheaper blends could fill the gap, then returned sheepishly after problems cropped up—lines gummed up, unexpected reactivity, batch-to-batch swings that burned costly downtime. In hospitals, the switch to other sedatives works for some cases, but clinical staff still stock Paraldehyde as a fallback. The job of a manufacturer is to trim out unnecessary excitement; the cleaner the batch, the fewer stories of things going wrong reach the end user.

    We engrain reliability from the reactor to the drum. That focus means turning out a product strong enough to survive shipping delays, pressure changes, and warehouse swings in temperature. A number on a TDS might say 98.5%, but what matters is a consistent reaction yield and shelf life—small shifts make headaches downstream. Rebuilding trust after a failed delivery takes years. We invest in real-world, grind-it-out processing because we’ve seen how easily less careful producers let corners slip. Our chemists flag off-colors, haze in the liquid, or faint whiffs of impurity and know when to hold the batch for further processing. That sort of care can’t be automated out or imported cheap from a contract plant half a world away.

    The Value of Doing It Ourselves

    Handling Paraldehyde as a manufacturer means more than managing risk and throughput—it’s about taking ownership so our buyers aren’t left exposed. Our direct sales teams work from the same plant where the material gets made, so customers pick up the phone and talk to the folks who’ve actually made the batch in question. We don’t rely on second-hand information or pass off specs someone else wrote. If there’s an issue, it comes back to us, and we fix it hands-on. Missteps get solved, not passed along in circles of blame.

    Years of managing closed-loop feedback gave us an edge. Experienced users aren’t impressed by flashy claims; they notice the nuances—like whether the inner drum seal holds, or if the paperwork matches the actual product. We’ve redesigned packaging, swapped out problematic seals for better ones, and set up a system for tracking every lot from the reactor to the client’s dock. These efforts show up in fewer complaints, simpler logistics, and customers who come back batch after batch.

    Challenges and What We’ve Learned

    Stability remains the number one concern for anyone buying Paraldehyde in bulk. It doesn’t do anyone good if the batch barely survives transportation, or if unexpected temperature swings trigger slow decomposition. We solved many of these headaches by reworking our cooling and heating cycles—taking what we learned from real failures, not just what textbooks suggested. We kept storage tanks shadowed, lines insulated, and ditched unstable glassware in favor of high-grade steel where metallurgy counts. Years of troubleshooting taught us to spot bad runs before they cause outages down the line.

    Safety also drives a good portion of our decisions. Our staff handle Paraldehyde daily—filling, testing, sampling, and loading shipping containers. Every accident or near miss with this material stays in memory. We invest in ventilation systems, automatic spill response, and restricted access, not because safety regulations force the issue, but because that’s how teams last in this field. Incidents from other facilities make the rounds in our safety meetings, and any hint of overexposure triggers a full review.

    Sustainability and the Road Ahead

    The next chapter for Paraldehyde manufacturing isn’t just about more efficient reactors or slightly better spec compliance. We face real questions from buyers and regulators about long-term sustainability—what happens at end-of-life, how waste processing looks, and whether solvents can be recaptured instead of dumped. In the chemical sector, every ton saved from landfill improves our costs just as much as environmental impact. We’ve started looping in solvent recovery steps, recycling process water, and partnering with downstream users to develop closed-loop strategies.

    Not everything has an easy fix—Paraldehyde’s strong odor makes vapor containment an ongoing project. We invested in new scrubbers and vapor recovery systems to address community and worker safety issues, and regularly update neighbors on emissions and incidents. Doing right by the environment isn’t a box-ticking exercise, but another way to earn community trust through transparency. The traditional face-to-face trust between chemical plants and their neighbors matters as much as extended documentation and inspections from government agencies.

    The Difference Between Us and the Rest

    In every plant, grumbling about commoditization never goes away. Chemicals made by weight or spec, with little thought given to practical use, create a market where nobody wins: end users get unpredictable results, manufacturers lose their edge, and overall quality slides. We’ve survived because we treat every shipment as both a promise and a test—a batch sent out today should match the one sent six months ago. That’s not marketing; it’s how you stay standing in a sector where reputation moves faster than shipping.

    Competitors can copy our specs, but they can’t replicate four decades of shortening cycle times, training operators to spot errors by smell or feel, or working directly with end users when things don’t go right. We tell new staff: “You have to care about the batch in front of you, the person down the line, and where that drum lands a week from now.” The results show in customer retention, not in spread sheets.

    What Makes Paraldehyde Unique in Practice

    Talking about Paraldehyde in theoretical terms misses the thousands of small improvements that separate a dependable batch from a catastrophic one. Stability over time, resistance to hydrolysis, predictable performance under a variety of operating conditions—these don’t happen by accident. The right purity, the exact acidity, moisture control honed across decades, and open access to real test data—that’s what buyers pay for, even if they don’t always see it spelled out in invoices or order forms.

    In the real world, mistakes cost time and trust. Our approach doesn’t chase after every new trend but focuses on the proven details: process controls to prevent runaway, real-time feedback on every batch, fast correction for any deviation, and honest answers for field problems. No substitute holds up over the long haul quite like Paraldehyde when it’s made the right way—by manufacturers with a stake in the outcome, experience in every step, and the willingness to improve based on the challenges our clients actually face.

    Final Thoughts from the Manufacturing Floor

    Chemical production isn’t glamorous, and the world rarely stops to thank the teams behind intermediates like Paraldehyde. But we know this: every safe hospital dose, every reliable resin batch, every research breakthrough owes something to the unbroken chain of consistent manufacturing. We keep our focus close—drum by drum, lot by lot, improvement by improvement. Every complaint is a lesson, every routine shipment a small triumph.

    For those who care more about finished results than marketing spin, the value of a well-made, responsibly handled product is clear. We commit ourselves to producing Paraldehyde with purpose and precision, free from shortcuts and empty claims. That’s the difference real manufacturing makes—and the reason users trust the product we put our name to, every single time.