Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

P-Nitroethylbenzene

    • Product Name P-Nitroethylbenzene
    • Alias 1-Ethyl-4-nitrobenzene
    • Einecs 209-576-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    407530

    chemical_name p-Nitroethylbenzene
    synonyms 4-Nitroethylbenzene, para-Nitroethylbenzene
    molecular_formula C8H9NO2
    appearance Yellow crystalline solid
    melting_point 51-53°C
    boiling_point 282°C
    density 1.15 g/cm3
    solubility_in_water Insoluble
    cas_number 619-90-3
    pubchem_cid 28475
    smiles CCc1ccc(cc1)[N+](=O)[O-]
    refractive_index 1.555 (predicted)
    flash_point 127°C
    storage_conditions Store at room temperature, in a dry place

    As an accredited P-Nitroethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250 mL amber glass bottle with screw cap, labeled “P-Nitroethylbenzene,” hazard pictograms, CAS number, and supplier details.
    Shipping P-Nitroethylbenzene should be shipped in tightly sealed containers, clearly labeled, and protected from physical damage. It must be transported according to local and international regulations for hazardous chemicals, including those covering flammable liquids and toxic substances. Ensure compatibility with packaging materials and avoid exposure to heat, sparks, and oxidizing agents during transit.
    Storage P-Nitroethylbenzene should be stored in a tightly closed container, in a cool, dry, well-ventilated area away from direct sunlight, heat, and sources of ignition. Keep it separated from strong oxidizing agents, acids, and bases. Label storage clearly and avoid mechanical shock. Ensure proper ventilation to prevent the accumulation of vapors and always use appropriate secondary containment.
    Application of P-Nitroethylbenzene

    Applications of P-Nitroethylbenzene in Industrial Manufacturing

    P-Nitroethylbenzene serves as a pivotal building block across several industrial synthesis routes due to its functional aromatic nitro group and ethyl substituent, enabling precise formulation and transformation into downstream products. Our expertise as a direct manufacturer ensures strict quality control and consistency, forming the foundation for reliable industrial usage. Below, we present verified application scenarios supported by real-world manufacturing practices, regulatory references, and integration flows.

    1. Intermediate for Agricultural Chemical Synthesis

    Producers of selective herbicides and insecticides in crop protection synthesize key active ingredients leveraging the oxidative or reductive transformation of this aromatic nitro compound. Its defined substitution pattern facilitates targeted molecular frameworks in industrial reactor loads. We support clients demanding process-specific adjustments to maximize conversion yields in continuous and batch plant configurations.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals (Pesticide Active Ingredient Synthesis)
    • FAO/WHO Maximum Residue Limits and Specification Requirements
    • ISO 9001:2015 for quality management in industrial chemical production
    • REACH Regulation (EC) No. 1907/2006 for precursor status

    Typical usage ratio

    • 3–8% of total reaction mixture by weight, adjusted based on the stoichiometry of active intermediate formation; optimized by in-line monitoring for selectivity according to target molecule structure.

    Downstream process integration

    • Charging into reaction vessels during the nitro group reduction or alkylation stage, prior to coupling or cyclization with specific heterocyclic precursors.

    Final product types

    • Phenoxy herbicides (e.g., 2,4-D analogues)
    • Pyrethroid insecticide intermediates
    • Chloroacetamide compounds for pre-emergent control

    2. Raw Material for Pharmaceutical Active Intermediate Production

    The pharmaceutical sector employs this compound as a controlled step in synthesizing more complex intermediates for APIs, where the ethyl and nitro functionalities modulate reactivity in hydrogenation and substitution steps. Our material’s purity and consistency help downstream pharmaceutical manufacturers meet the tightest batch reproducibility and impurity profile requirements under GMP frameworks.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (Ph. Eur.) monographs for chemical purity and safety
    • USP–NF requirements where applicable for precursor validation
    • EHS regulations for controlled substances precursors—national laws (e.g., 21 CFR in the U.S.)

    Typical usage ratio

    • 5–12% of initial reaction charge, tailored to desired reduction product yield and control of by-products for specific pharmaceutical intermediates.

    Downstream process integration

    • Integrated during catalytic hydrogenation or nucleophilic aromatic substitution stages, with rigorous temperature and pressure controls to safeguard reaction specificity.

    Final product types

    • Precursors to cardiovascular and CNS pharmaceutical agents
    • Key intermediates for anti-inflammatory drug constituents
    • Advanced building blocks for custom contract synthesis batches

    3. Precursor for Dye and Pigment Manufacturing

    Dyestuff factories utilize this aromatic nitro compound in azo and nitro dye production, benefiting from its defined substitution to achieve precise chromophore architectures in batch and continuous dye synthesis. The feedstock’s quality directly influences shade intensity, colorfastness, and compatibility with downstream formulation in textile and plastics coloration.

    Industry compliance standards

    • ETAD (Ecological and Toxicological Association of Dyes and Organic Pigments Manufacturers) guidelines
    • OEKO-TEX® Standard 100 restrictions for textile chemicals
    • REACH SVHC restrictions (for intermediates and input chemicals)
    • ISO 14001 for environmental management in colorant facilities

    Typical usage ratio

    • 10–20% as charged depending on target pigment concentration; the proportion is adjusted by desired color strength and process yield for specific azo coupling reactions.

    Downstream process integration

    • Added to diazotization reactors for subsequent coupling with aromatic amines or phenols, followed by isolation and standard washing/filtration.

    Final product types

    • Azo dyes for polyester and cotton fibers
    • Nitro-based colorants for printing inks
    • Organic pigments for automotive and industrial coatings

    4. Manufacture of Fine Chemical Intermediates for Plastics Additives

    Specialty chemical manufacturers rely on this nitroethyl aromatic as a backbone for fine chemical intermediates that function as plasticizers, antioxidants, and stabilizer precursors in polymer processing. The feedstock’s ethyl substitution facilitates subsequent ring functionalization and integration into high-performance additive systems essential for durability in thermoplastic compounds.

    Industry compliance standards

    • ISO 9001:2015 for process and documentation
    • European Chemicals Agency (ECHA) REACH compliant substance registration
    • FDA 21 CFR for additives in food contact plastics (where applicable to derivative use)
    • ASTM D2566 for evaluating additives performance in polymer matrices

    Typical usage ratio

    • 1–7% in additive synthesis reactors, dependent on additive target load and process optimization to control side-product formation during ring functionalization and subsequent processing.

    Downstream process integration

    • Fed into sequential nitration or alkylation units as a core aromatic substrate, followed by downstream esterification or phosphorylation under controlled temperature programs.

    Final product types

    • Monomeric plasticizers for flexible PVC and polyurethane processing
    • Antioxidant intermediates for polymer stabilization systems
    • Specialty stabilizer precursors for automotive plastics and engineering resins

    5. Synthesis of Specialty Aromatic Compounds for Electronic Chemicals

    Manufacturers in the electronic chemicals sector integrate this compound to access tailor-made aromatic intermediates, vital for producing optoelectronic materials and fine chemical agents in display panel and semiconductor fabrication. Feedstock purity, trace metal content, and batch reproducibility are critical to downstream process yields and final device characteristics.

    Industry compliance standards

    • IPC-CH-65B (Chemical Handling Requirements)
    • RoHS 2 (2011/65/EU and amendments on hazardous substances)
    • REACH compliance for input materials
    • ISO 14644 for contaminant control in electronic chemical production

    Typical usage ratio

    • 0.5–3% by weight in specialty aromatic synthesis, precisely modulated for batch size and ring-substitution requirements of target electronic-grade functional molecules.

    Downstream process integration

    • Introduced at the initial synthesis or post-purification derivatization step for direct integration into optoelectronic or photoresist precursor workflows.

    Final product types

    • Photoactive compounds for microelectronics photolithography
    • Aromatic intermediates for OLED and display material producers
    • Specialty solvents and photoresist agents in semiconductor manufacturing
    Free Quote

    Competitive P-Nitroethylbenzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    P-Nitroethylbenzene: A Closer Look from the Manufacturer’s Floor

    Built on Chemistry, Shaped by Experience

    Crafting P-Nitroethylbenzene starts long before production fires up. Over the years, our team worked through every production nuance, finding efficiencies that matter to our customers. In a lab no bigger than a supply closet, the earliest batches showed inconsistencies that couldn’t go into downstream synthesis. Slowly, we built a process that produces clear, consistent P-Nitroethylbenzene with reliable purity every time. That’s not just a promise on paper. Technicians on the line know the subtleties of the finished product, watching for batch anomalies instead of ignoring them. Quality doesn’t come from an auditor walking the halls—it takes a culture where every hand on the vessel cares about the next customer in line.

    P-Nitroethylbenzene: What Sets It Apart

    P-Nitroethylbenzene offers some distinct behavior compared with its analogs, especially in selective intermediate synthesis. Its molecular structure gives it a unique push-pull effect, making it more reactive in certain nitration or alkylation steps than P-nitrotoluene or nitropropylbenzene. Chemists in resins or pharmaceutical development see faster conversions and cleaner product isolation with it. If you’re accustomed to managing byproducts in your separation train, P-Nitroethylbenzene often reduces that headache.

    Molecular consistency remains the top demand we hear from technical leads. Dull yellow color, low moisture, and single-digit ppm for critical impurities are the standard in our batches. Analytical teams check every lot, aiming for more than just reporting data—we talk openly about what each result means for the mix tank. Each metric, right down to crystalline shape, has a story rooted in lab and plant-floor decisions. There’s a pride in seeing a flask of our P-Nitroethylbenzene across a customer’s microscope, knowing every particle reflects the effort on our end.

    Packing the Right Specification for Real-World Synthesis

    The production line handles a wealth of feedstocks, but nothing leaves the door unless it stands up to the scrutiny of researchers and process engineers alike. Each drum of P-Nitroethylbenzene, model PE-2102, carries a lot-specific certificate—no boilerplate guarantees there. We target a minimum purity of 99%, and our moisture content consistently falls below 0.1%. Color and trace metals get special attention. The technical community often asks about sulfur and halide contaminants because even trace levels can skew reactions downstream. We’ve tightened controls on those, using additional purification loops that keep those figures reliably low.

    Each detail, from packaging to analytical logs, gets recorded and inspected before shipping. This isn’t to tick regulatory boxes but to help users spend less time cross-checking their own controls. Reaction development sometimes uncovers a new, unexpected sensitivity, and our plant responds by adjusting analytical focus. Recently, several partners exploring new battery electrolyte synthesis flagged residual organic acids as a risk. We set up extra post-batch testing to resolve their concerns—result: lower deviation, smoother trials, and adaptations that benefit our wider user base.

    End-Uses Driven by Feedback

    Pharmaceutical firms, agrochemical developers, dye chemists, and specialty resin producers have all found their own value in consistent-quality P-Nitroethylbenzene. Plenty of requests go deeper than “just in-spec”—customers share insights on how our product behaves in real-world reactors. Those who tried switching from p-nitrotoluene reported not only improved yields but easier purification. In the world of polymers, engineers have told us how solubility and phase separation improve when using our P-Nitroethylbenzene compared with other derivatives.

    The product’s role as an intermediate in synthesizing ether-linked and ester-linked compounds has increased, especially in newer drug candidates. Its chemistry simplifies certain coupling steps, helping to avoid multiple halogenation rounds or risky reductions. Several coatings manufacturers outlined how the nitro functionality on our compound allows for straightforward modification, supporting the production of robust adhesion promoters. By paying attention to these details, our operations accommodate slight adjustments batch-to-batch, whether in crystallization or drying protocol, depending on evolving industry needs.

    Listening to Real Process Concerns

    Customers often ask about reactivity differences between P-Nitroethylbenzene and its close relatives. Our team spent months running side-by-side trials with p-nitrotoluene, logging not just yields but the shape of the process curves. Findings revealed that P-Nitroethylbenzene reacts with certain reagents more completely, often producing fewer side-chain oxidation products, which leads to simpler downstream purification.

    Chlorinated impurities present another concern. Operations teams in fine chemical and pharmaceutical plants flag even trace carryover from legacy process lines. Our facility dedicates equipment solely to nitroalkylbenzene runs, minimizing this risk—and every instrument, from reactor to final drum, gets validated and cleaned down to the last gasket. Over one twelve-month period, customer-reported impurity levels dropped to near-zero after these improvements.

    Comparing with Related Nitro Compounds

    Some customers weigh P-Nitroethylbenzene directly against p-nitrotoluene or nitropropylbenzene, pointing out that downstream reaction times often differ. In our own side-by-side experiments, the nitroethyl group supports more selective reactions in certain cross-couplings, where the methyl or propyl analogs can generate off-path isomers. This aspect appeals to chemists looking to fine-tune their end products without repeated chromatography. Data from several synthetic routes in-house showed more consistent performance metrics—including temperature stability and solubility—when switching over to P-Nitroethylbenzene, especially under conditions with less forgiving reaction windows.

    For those scaling up, differences in volatility and melting point can tip the balance either way. Resourceful engineers in resin plants and pilot facilities highlight how our product’s melting point cuts down on energy use during solvent removal. No one wants an unexpected bump in operational costs from a small change in feedstock. We’ve seen plants trim batch times by hours just by switching to our P-Nitroethylbenzene, thanks to these thermophysical properties.

    Handling and Storage: Practical Observations

    Lab teams always ask about handling. P-Nitroethylbenzene doesn’t emit the sharp, acrid fumes of some nitro analogs, making it easier to work with in open systems. Standard PPE protocols cover routine use, but years of drum and tanker loading taught our team what tweaks actually prevent spills and operator exposure. For long-term storage, a cool, dry, sealed environment keeps the product stable. Staff log every shipment out, noting color and particle changes—not just for audit, but to catch rare stability shifts before the next process run.

    We learned early on that moisture management is not a one-and-done fix. Even trace amounts in a loading bay environment can introduce quality drift in stored product. Investing in overlapping ventilation and drying steps keeps those figures below the detection limits. Customers who faced clumped or discolored drums switched to our process and fed back real gains in their operation stability. Our shipping team routinely checks seals and headspace every time a drum goes out, logging anything unusual for immediate follow-up. These steps signal to end-users that they’re not just another line item—they’re part of why we ensure every batch measures up.

    Environmental and Safety Realities

    Regulatory requirements for nitro aromatics keep evolving. Instead of reacting after the fact, our facility monitors process air and effluent for even trace nitro compound emissions. That’s not just about laws; it’s a respect for the neighborhoods around us. Waste process streams get neutralized before leaving the property, and we track every outgoing drum for chain-of-custody, making sure nobody downstream gets a surprise. Staff training covers the full lifecycle—from handling raw nitro feedstocks to cleaning reactors—because safety lives in habits, not handbooks.

    For customers with stricter standards—pharma or electronics—extra certificates often make the rounds. Every data package includes more than figures: chromatograms, IR spectra, and even process notes get shared upon request, so nothing gets lost in translation between our batch and your bench. Gaps in regulatory knowledge can slow projects down, so we host regular webinars for teams looking to future-proof their process compliance.

    Supporting Innovation on the Customer’s Side

    Each new molecular project brings different demands: solubility, reactivity, or reduced waste. Our conversations with application scientists often drive minor but impactful changes at the plant—tighter particle size control for those needing rapid solubilization, or targeted impurity control when high-precision synthesis matters. Everything starts with direct feedback. Nobody just follows paper specs if they want a synthesis to scale successfully.

    Agrochemical developers shared how changing a single starting molecule can reroute development timelines by months. We tested custom purification schemes to squeeze another 0.05% in purity, which shaved days off their downstream prep cycle. Every lab across the globe operates under its own constraints, budgets, and optimization pressures. When a customer’s plant in Southeast Asia requested alternate packaging to suit tighter warehouse limitations, our logistics group tweaked the palletization, avoiding problems on arrival.

    Market Dynamics and Shifting Demand

    Recent years pushed more users towards specialty nitro aromatics due to changing supply streams in basic petrochemical feedstocks. Feedback from multiple regions shows that each market cycle multiplies the need for more reliable, consistent intermediates. One specialty pharma partner ran side-by-side batches and found that P-Nitroethylbenzene’s purity and byproduct profile made their final isolation steps more predictable, even as oil prices and raw materials shifted. That kind of stability in quality keeps plants running during tight market swings.

    Growth in electric vehicle R&D and battery research fueled new questions about nitrobenzene derivatives as possible electrolyte modifications. Research teams in this domain want to know the nitro group’s influence on ion mobility and stability. We responded by synthesizing controlled micro-batch runs, taking feedback on test results to refine both process and quality benchmarks further. That back-and-forth built trust between our lab and innovators tackling global electrification challenges.

    Continuous Improvement—Lessons from the Plant

    Nothing on the manufacturing floor stands still for long. Each adjustment in route, solvent, or purification routine teaches something new. Years ago, a series of minor process shifts cut both batch times and waste generation—ideas sparked by customer questions during a technical exchange, later tested at small scale before rolling out plantwide. Those improvements now show up in feedback: fewer complaints, higher repeat orders, cleaner analytics.

    Challenges remain. Supply chain hitches—whether raw material or downstream logistics—still test our agility. Our procurement and operations teams have backup suppliers on deck and keep extra stock for just-in-case moments. Customer priorities heat up or cool down with every geopolitical stress test; our plant flexes production to avoid lapses in supply. When a hurricane in a key supply region threatened deliveries, our logistics group rerouted through alternate hubs, keeping commitments intact. Each crisis sharpens the system, sent straight from plant floor experience instead of meeting-room theory.

    The Value of Real Connections in Chemical Supply

    Transparency and responsiveness aren’t slogans—they’re daily routines on our team. Peer-to-peer calls, routine progress updates, and calls to line managers form much of the glue that holds our customer relationships together. That communication loop means we don’t just deliver P-Nitroethylbenzene; we troubleshoot applications, review analytical data, and adapt delivery schedules to fit actual needs. The team on shipping lines traces every drum, and if a partner flags an issue on arrival, the feedback loops directly into a root-cause review and solution, fast.

    Trust takes shape from small, reliable acts repeated year after year: No mix-ups between nitro grades, no sudden spec shifts, no unexplained delays. We know what headaches inconsistent intermediates create downstream—a nervous batch, extra purification, or waste disposal hassles. Our goal—relentlessly—remains to take the variability and surprise out of the supply equation.

    Collaboration Drives Every Advance

    Through a mix of hands-on plant work and open conversations with customers across chemistry and engineering, we built a product that addresses the real-world challenges faced by researchers and large plant operators alike. Progress sprang from more than just internal R&D. It’s shaped by the practical wisdom of chemists, engineers, and technicians on both sides of the supply chain.

    That collaboration led to unexpected wins—such as refining purification stages in response to a customer’s syntheses, or custom packaging for international clients with unique handling requirements. Adapting to those requests isn’t automatic; it arises from a deliberate decision to listen closely, try new approaches, and not shy away from the extra work needed to maintain high standards. That’s the effort behind every drum, bottle, or tanker of P-Nitroethylbenzene leaving our facility.

    Looking Ahead

    Markets change, experiments fail and succeed, but the relationship between supplier and innovator remains at the heart of specialty chemical progress. Our teams, from plant operators to technical support staff, face each new product request or problem in the same way: find out what the customer actually needs, work out the most effective process, and push forward.

    The landscape for organic intermediates will get no less demanding—competition, regulation, and end-use complexity all march onward. Yet the fundamentals will hold: listen, respond, and constantly refine. Every kilo of P-Nitroethylbenzene on our site carries that work. We focus on what matters most, drawn from practical experience, so our customers can turn new ideas into successful processes with fewer obstacles along the way.