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O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate

    • Product Name O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate
    • Alias quinaphos
    • Einecs 253-698-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    601515

    Chemical Name O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate
    CAS Number 2503-23-3
    Molecular Formula C12H15N2O3PS
    Molecular Weight 298.30 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 410.1 °C at 760 mmHg
    Density 1.26 g/cm³
    Solubility Slightly soluble in water
    Flash Point 202.7 °C
    Refractive Index 1.562
    Synonyms Quinoxalin-2-yl diethyldithiophosphate
    Structure Type Organophosphorothioate
    Stability Stable under normal conditions
    Storage Conditions Store in a cool, dry, and well-ventilated place
    Purity Typically ≥ 97%

    As an accredited O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle labeled with chemical name and hazard symbols, tightly sealed, containing 100 grams of O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate.
    Shipping O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate should be shipped in tightly sealed containers, away from moisture and direct sunlight. It must be clearly labeled as a hazardous chemical and handled in accordance with local, national, and international transport regulations, using appropriate protective packaging to prevent leaks, spills, or accidental exposure during transit.
    Storage O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from heat, sparks, and open flames. Keep it away from incompatible materials such as oxidizing agents. Store under inert atmosphere if recommended. Ensure proper labeling and access only to trained personnel. Use secondary containment to prevent leaks or spills.
    Application of O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate

    Applications of O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate in Industrial Manufacturing

    O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate is a phosphorothioate compound widely integrated into specialized chemical manufacturing lines due to its specific reactivity and performance profile. As a direct producer with deep focus on end-user quality control and process stability, we support downstream partners by supplying consistent, traceable batches for use in advanced agrochemical synthesis, seed treatment solutions, crop protection agent production, and insecticide intermediate formulation. Below, practical application scenarios are outlined in detail with reference to current regulation, formula design, process step, and resulting finished product categories.

    1. Active Ingredient Synthesis for Systemic Insecticides

    Within agrochemical synthesis, O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate is utilized at the stage of constructing core phosphorothioate moieties required in next-generation systemic insecticidal actives. Chemical engineers add this compound during the phosphorylation phase, taking advantage of its high selectivity and controlled hydrolysis profile to ensure reliable yield and minimal side reactions. Quality assurance staff validate batch integrity using HPLC methods in compliance with industry regulatory guidelines for purity and residuals. Production plants often adjust the input ratio based on intermediate conversion efficiency, balancing target assay requirements and downstream process economics to optimize active ingredient output.

    Industry compliance standards

    • FAO/WHO Specification for Pesticides Quality Control
    • ISO 17025:2017 Laboratory Accreditation
    • Regulation (EC) No 1107/2009 for Plant Protection Products
    • China GB 4839-2009 for Pesticides Technical Material

    Typical usage ratio

    • Applied at 0.85–1.2 molar equivalents relative to the quinoxaline precursor, or 5–15% by weight depending on the targeted insecticide molecule and reactor batch scale; specific ratio determined by active ingredient assay requirements and batch reactivity profile.

    Downstream process integration

    • Introduced during the phosphorylation reaction step via controlled temperature addition; batch-wise in stirred tank reactors with real-time pH and conversion monitoring.

    Final product types

    • Technical grade organophosphorus insecticides (e.g., quinoxaline-based actives)
    • High-purity insecticide intermediates for further formulation
    • Soluble concentrates (SL) and emulsifiable concentrates (EC) for crop protection

    2. Seed Treatment Formulation Manufacturing

    O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate delivers targeted antifeedant and ovicidal properties, making it a preferred synthetic intermediate in the formulation of novel seed treatment agents. Material is added to premix tanks during the compounding of protectant blends, where process technicians control viscosity and dispersion to achieve uniform distribution across active coatings. Regulatory policies mandate validated residual and leachate assessment prior to scale-up. Product development staff determine additive ratios through greenhouse trialing, adjusting dose for seed mass, crop type, and regional legislation on permissible application rates.

    Industry compliance standards

    • ISO 9001:2015 for Quality Management Systems
    • OECD Guidelines for the Testing of Chemicals, Section 6: Seed Treatment
    • US EPA 40 CFR Part 180 Tolerances and Exemptions for Pesticide Chemical Residues
    • EU Regulation No 284/2013 for Data Requirements for Plant Protection Products

    Typical usage ratio

    • Formulated at 0.25–0.6% w/w in finished seed coatings; adjusted based on seed type, targeted insect pressure, and region-specific residue tolerance limits.

    Downstream process integration

    • Premixed with polymeric binders and micronutrients in seed coating drum or closed blend tank before application to untreated seed via rotary seed treaters.

    Final product types

    • Treated corn, wheat, rice, and vegetable seeds with enhanced protection profiles
    • Commercial seed coating slurries
    • Ready-to-use seed protectant liquid and dry powder blends

    3. Intermediate for Crop Protection Agent Formulation

    In the manufacture of next-generation crop protection agents, O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate functions as a crucial synthetic building block for the creation of heterocyclic phosphorothioate derivatives. Production chemists introduce this material at the early condensation or esterification step, ensuring precise temperature and pH control to facilitate efficient coupling. Downstream purification processes require adherence to global MRL (Maximum Residue Limit) standards, with batch samples subjected to confirmatory analytical testing for structural byproduct minimization. Material input levels are decided according to final agent loading targets and efficiency parameters established during pilot runs.

    Industry compliance standards

    • Global GAP Traceability and Residue Control Protocols
    • Japanese Food Sanitation Law on Agricultural Chemicals
    • Codex Alimentarius Pesticide Residues Guidelines
    • EPA PRIA (Pesticide Registration Improvement Act) Submission Protocols

    Typical usage ratio

    • Integrated at 1.5–3.5% by weight into synthesis reaction batch, with precise quantity optimized for the target class of active crop protection agents and consistency of the downstream formulation process.

    Downstream process integration

    • Dosed at initial reaction setup in multi-step batch or semi-continuous reactors; followed by fractionation and solvent exchange prior to blending into bulk agent premixes.

    Final product types

    • Phosphorothioate-based fungicides and insect growth regulators
    • Custom-blended crop protection wettable powders and granules
    • Tank-mix compatible crop protection premixes for commercial agriculture

    4. Raw Material for Insecticide Intermediate Formulation

    Downstream insecticide manufacturers employ O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate as a raw material for the synthesis of specific organophosphorus intermediates used in the production of broad-spectrum insecticidal products. Operators charge this compound at the precursor synthesis step, monitoring throughput rates to align with next process cycle times and yield optimization needs. All input batches require full traceability and compliance with registered specification sheets. Adjustments to ratio are guided by intermediate purity assays and alignment with the purity profile demanded by downstream formulation steps.

    Industry compliance standards

    • REACH Regulation (EC 1907/2006) on Chemical Registration
    • Technical Specification (ISO 9001:2015) for Quality Systems in Pesticides
    • Hazardous Substances Control Act of Taiwan (RoHS directive)
    • India Insecticide Act, 1968 – Technical Grade Materials

    Typical usage ratio

    • Used at 6–12% by weight, modified according to target intermediate molecular design and downstream process mass balance; precise percentage set after scale-up pilot verification and QC checks.

    Downstream process integration

    • Added as a primary charge in organophosphorus intermediate synthesis vessels prior to cyclization or esterification; quality samples drawn for in-process GC validation.

    Final product types

    • Technical grade insecticide intermediates for downstream conversion
    • Active concentrate supply for regional insecticide plants
    • Stabilized intermediates shipped for further agrochemical agent production
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    Certification & Compliance
    More Introduction

    O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate: A Closer Look from the Manufacturer’s Bench

    Direct From the Factory: Our Experience with O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate

    Years of hands-on synthesis and quality control have shown us that O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate stands apart in today’s portfolio of agrochemical actives. Our facility doesn’t just push batches forward; we optimize every cycle by listening to feedback from users in the field and at formulation tables. Every day, we grapple with the product’s true performance parameters—not theory, but practical output, from crystallization through to bulk stability.

    Product Model and Specifications: Real-World Production Realities

    Our current production focuses on the technical grade of O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate, engineered for pesticide synthesis. We control impurities well below accepted tolerance levels, supporting those integrators who demand consistent results in blending, dispersion, and reactivity. Batch-to-batch repeatability reflects the underlying process design: our reactors maintain tight temperature and mixing parameters, particularly to suppress unwanted by-products that can complicate downstream registration or formulation.

    The crystalline product maintains its characteristic color and flow across many temperature ranges, a benefit for both transportation and high-throughput production sites. We see less caking and agglomeration compared to other phosphorothioates, due to years spent modifying solvent systems and post-crystallization drying curves. Moisture content remains stable under ordinary atmospheric storage—one less headache for purchasing teams managing buffer inventories.

    Application Fields: Field Use Above the Laboratory Hype

    From our factory floor to client warehouses, the main story centers on agricultural chemistry. O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate sees most use as a critical intermediate in the synthesis of certain insecticides that demand both selectivity and stability. Processors depend on its compatibility with a range of common solvents and its readiness to react under mild conditions—variables that save both time and overhead, especially in resource-constrained locations.

    We receive feedback from blending facilities in diverse climates. They note fewer unexpected odor issues and fewer compatibility complaints during tank mixing. One plant manager in Southeast Asia pointed out that, in their batch operation, our material runs more predictably when loaded to scale-up vessels—minor variances in solubility behavior could have threatened timely campaign completion, but in practice this product has shown repeatable performance.

    Upstream innovation matters too. Our collaborations with downstream formulators have allowed for real-world input into particle sizing and dust minimization. Worker safety often weighs as heavily as technical specification once mixing shifts and exposure durations stretch past theory into reality. Quality consistency has a human dimension—operators trust in the tools at hand.

    Industry Shifts and Why Ingredients Matter

    The pressure on active ingredient manufacturing only grows. Regulatory changes, raw material price surges, and shifts in global demand make simple “commodity” approaches obsolete. Our O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate doesn’t emerge from a faceless process. Much of the value comes from incremental, sometimes hard-earned improvements pushed forward by on-site chemists and engineers who’ve had to solve real problems: impure raw materials, inconsistent supply of precursors, variable reaction yields. Some of our most effective tweaks came about not in project meetings, but from direct conversations on the production line, where process technicians outlined where flow or temperature bottlenecks actually occurred.

    This culture of feedback and process troubleshooting has led to shorter downtime between campaigns. The impact reaches beyond our gates—formulators see not just technical documents, but practical assurance that critical intermediates won’t be the weak link. This is especially acute for companies launching new pest management products, where uncertainty or unpredictability in ingredient quality can force costly delays or hurried last-minute reformulation.

    Distinguishing Ourselves: What Sets This Material Apart

    Many chemical manufacturers offer phosphorothioates, but not all can claim full vertical integration from raw material acquisition to final technical grade product. Our operation controls each stage internally, so surprises from supplier changes or raw material inconsistencies show up quickly in trial batches, rather than unnoticed in large-scale runs. This vigilance allowed us to spot a number of problematic input sources, which we replaced before they could impact large-scale output or downstream performance.

    We also focus on minimizing batch variability. Inline monitoring and tight feedback control ensure that each lot meets rigorous purity targets. We invest in regular instrument calibration rather than just relying on periodic outside audits. Anything less jeopardizes the day-to-day reliability needed by formulators working under tight regulatory and economic constraints.

    Shipping stability is a key differentiator. Manufacturers like us who ship bulk volumes across continents see the reality of thermal cycling, repeated handling, and time spent in non-ideal transit conditions. Our refinements in packaging and post-processing have brought down the incidence of material degradation seen upon arrival at blending or formulation plants far from our own facilities.

    Responsiveness counts too. We maintain open channels for customer troubleshooting. Requests for small specification tweaks—tightening a moisture spec, for example—don’t vanish into a bureaucratic black hole. They become part of our next campaign’s process planning. The culture inside a chemical factory matters; flexibility leads to stronger, longer-lasting partnerships with end users far beyond the initial sale.

    Comparing Functional Performance in the Field

    We’ve had new clients approach us after persistent issues with competitor materials ranging from unpredictable caking to interrupted solubility, leading to delays in sprayer loading or uneven initial dispersions. Our technical teams partnered with these groups during the switchover, running rapid pilot studies and providing side-by-side blending trials. In these field settings, O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate delivered more consistent dissolution rates and presented fewer equipment cleaning issues, according to client maintenance logs.

    This track record didn’t come overnight. Early process blocks required tough choices regarding raw material suppliers, logistical partners, and internal re-training for production line workers. Successful adaptation in surfactant choice during crystallization, along with careful temperature ramping, removed many of the marginal impurities that can build up through poor process sequencing. Each of these seemingly small operations reflects an in-depth focus on the nitty-gritty details, which, from experience, are often more decisive than bigger, abstract process modifications.

    Direct conversations with plant engineers revealed that some phosphorothioate intermediates from other sources carried trace residues that, while within technical tolerance on paper, built up in finished formulations at problematic levels. We responded to these concerns by reworking our own purification pathways, even at higher operating cost, since our long-term partnerships matter more to us than temporary cost reductions.

    Worker Safety, Environmental Responsibility, and Product Confidence

    Factories live or die on their approach to both worker and environmental safety. From the first day of planning these synthesis lines, our team put as much emphasis on air quality controls and closed-system material handling as on chemical purity targets. O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate, produced to our current protocols, leaves us with confidence that operators and surrounding communities face lower risk of fugitive dust or accidental exposure during both production and packaging.

    We collect emission and effluent data daily. These logs don’t gather dust—they feed directly into weekly team meetings, where compliance and best-practice improvements rank alongside yield and throughput as measures of a successful run. This attention to plant safety has made regulatory inspections smoother, but far more importantly, it means managers on site spend less time firefighting and more time focusing on higher-value technical work.

    On the customer side, documented batch traceability and real-world stability data let end users handle the material with the same confidence they have when pulling from their own bulk stocks. Field staff consistently ask for less support troubleshooting issues that stem from upstream ingredient quality. This frees up technical resources for developing new actives, rather than getting bogged down in repeats of old operational headaches.

    Looking Ahead: Evolving With the Industry

    Chemical manufacturing, especially for specialty actives, never stands still. End-user requirements change as new technologies, stricter local regulation, or emergent resistance profiles shift product priorities. In this environment, a static product line won’t cut it. We treat every new order for O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate as a new opportunity—a chance to learn more about how it serves actual needs in field and factory. This constant evolution is made possible by maintaining our own R&D capability and close, day-to-day connection with operational and formulation partners.

    Occasionally, raw material disruptions force short-term changes in operating conditions. Our regular scenario planning helps us respond quickly. We try not to outsource key process know-how, since external dependencies introduce risk that only emerges late—often too late to prevent supply interruptions. Full in-house control, from process design through to maintenance, supports a more predictable product every time.

    Customer feedback continues to push us. Integration with new adjuvant systems or compatibility with up-and-coming formulation technologies can’t get solved by sitting in a boardroom. Shop-floor chemists and engineers—folks in direct line contact with the process—carry much of the responsibility for small but critical technical progress. By listening to their observations and maintaining a robust internal training pipeline, we keep O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate at the technical edge, rather than playing catch-up.

    Supporting Partners: Building More Than a Transaction

    Relationships in this industry run on trust. Our focus on O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate stems from years working side by side with technicians, formulation chemists, and procurement managers. They rely on us for timely deliveries, but more importantly, for openness about challenges and possible improvements—not just the smooth parts of the process, but also issues that arise and how we tackle them.

    Real manufacturing expertise doesn’t show up in glossy brochures or standard specification sheets. It’s found in how quickly a supplier responds to an off-spec report, or how thoroughly technical teams follow up after a process hiccup. Our openness, rooted in firsthand industrial experience, translates into less guesswork for end users when deciding how to integrate a batch into a new campaign or scale up a promising formulation. This approach has built a level of confidence that’s hard to quantify, but which our partners regularly say differentiates us from other technical material suppliers.

    Today’s manufacturing runs can’t afford repeated downtime or unanticipated compatibility issues. Our gains in process flexibility and internal communication feed directly into the reliability of each shipment. Partners reporting fewer incidents when using our O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate aren’t just relaying abstract satisfaction—they give details of shorter changeover times, fewer batch rejections, and reduced operator training requirements when introducing our material compared to alternatives sourced elsewhere.

    Addressing Challenges: Practical Solutions, Not Theoretical Promises

    Like every chemical operation, we’ve faced bottlenecks—raw material fluctuations, uncertain customer specifications, or unexpected changes in market demand. Our process experience provides a way forward. For example, during a recent global shortage of a key phosphorothioate precursor, our team mobilized alternative synthetic routes that kept material in our warehouses and on our customer’s shop floors. These shifts required the full engagement of purchasing, technical, and production personnel. Coordination and clear communication made the difference, not simply rote adherence to written procedures.

    Another recurring issue has been transportation risk, with extended journeys exposing cargo to unplanned heat or high humidity. Our packaging lines now apply real-time monitoring to container units, and feedback from affected partners has led to adjustments in barrier materials and load staging. Shipments arrive closer to the physical and chemical state they left our plant, reducing headaches across the distribution chain.

    Collaboration with end users on specific pain points led to changes beyond the lab bench. Formulators needed reduced dust to protect their operators and minimize cross-contamination. We retooled our milling and sieving operations to cut fines without increasing cost or reducing yield. Achieving these improvements only came from consistent dialogue and iterative process upgrades—it didn’t result from theory divorced from the realities of day-in, day-out production.

    Conclusion: A Manufacturer’s Commitment Beyond the Sale

    O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate reflects more than the sum of its technical data and chemical specification. Every step from raw material sourcing, process development, on-line testing, to final packaging incorporates valuable lessons gathered over years of industrial-scale chemical production. Our focus always centers on stable product quality, transparent operation, flexible response to customer needs, and the real-world implications for downstream safety and productivity.

    We stay committed to improvement—not through empty marketing, but through open engagement with partners both close to home and around the world. Our drive to add value through technical know-how, fast response, and continuous improvement model provides confidence that each shipment of O,O-Diethyl-O-Quinoxalin-2-Yl Phosphorothioate is more than just another commodity. For us, it’s a reflection of the hard work, experience, and ongoing commitment of everyone on our team, from chemistry bench to loading dock, and onward to the fields and facilities where results are counted in greater crop yields, safer workplaces, and a stronger supply chain.