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O,O-Diethyl-O-(4-Nitrophenyl) Phosphate

    • Product Name O,O-Diethyl-O-(4-Nitrophenyl) Phosphate
    • Alias parathion
    • Einecs 204-047-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    196931

    IUPAC_Name O,O-Diethyl O-(4-nitrophenyl)phosphate
    CAS_Number 311-45-5
    Molecular_Formula C10H14NO6P
    Molecular_Weight 275.19 g/mol
    Appearance Yellow crystalline solid
    Melting_Point 39-41 °C
    Solubility Slightly soluble in water
    Density 1.34 g/cm3
    Refractive_Index 1.500 (approximate)
    Flash_Point 183.2 °C
    Synonyms Parathion, Diethyl p-nitrophenyl phosphate
    PubChem_ID 6195
    EC_Number 206-237-8
    UN_Number 2783

    As an accredited O,O-Diethyl-O-(4-Nitrophenyl) Phosphate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, tightly sealed, labeled with hazard symbols and product details, containing 100 grams of O,O-Diethyl-O-(4-Nitrophenyl) Phosphate.
    Shipping O,O-Diethyl-O-(4-Nitrophenyl) Phosphate is shipped in tightly sealed containers, compliant with chemical safety regulations. Transport is typically by ground or air as a hazardous material, with clear labeling and appropriate documentation. Packaging ensures protection from moisture, heat, and physical damage, adhering to international chemical transport standards.
    Storage O,O-Diethyl-O-(4-Nitrophenyl) Phosphate should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from sources of heat, ignition, and incompatible materials such as strong oxidizers. Protect from moisture and direct sunlight. Label containers clearly and keep them in a secure location accessible only to trained personnel.
    Application of O,O-Diethyl-O-(4-Nitrophenyl) Phosphate

    Applications of O,O-Diethyl-O-(4-Nitrophenyl) Phosphate in Industrial Manufacturing

    As a direct manufacturer of O,O-Diethyl-O-(4-Nitrophenyl) Phosphate, we serve industry leaders who require specialized phosphates for advanced manufacturing. Below, we outline genuine downstream segments where this compound plays a critical functional role, including application specifics, compliance, process steps, and resulting end products.

    1. Organophosphate Insecticide Formulation

    Major agrochemical producers use this compound as a key active ingredient for formulating contact and systemic insecticides. The manufacturing process requires precise control of ingredient ratios and technical expertise in solvent selection and batch blending, due to the material’s specific reactivity and targeted pest spectrum. Proper handling and quality assurance protocols ensure compliance with regulatory restrictions and worker safety regulations.

    Industry compliance standards

    • FAO/WHO Pesticide Specifications for Technical Grade Active Ingredients
    • US EPA FIFRA regulations for pesticide active substances
    • REACH Annex XVII for chemical use restrictions
    • China ICAMA registration and residue limits

    Typical usage ratio

    • Active ingredient content: 10–50% in technical concentrate, adjusted per crop and pest target
    • Final EC or WP formulations: 0.5–5% inclusion, customized per product strength requirements
    • Ratios altered based on local regulations and climatic pest pressure

    Downstream process integration

    • Introduced during concentrated pre-blend stage, prior to emulsifier or carrier addition
    • Subjected to temperature-controlled mixing to prevent degradation and maintain assay
    • Integrated into automated dosing systems for quality and batch traceability
    • Batch tested for purity (GC), isomer profile, and stability before packaging

    Final product types

    • Emulsifiable Concentrate (EC) insecticides
    • Wettable Powder (WP) formulations
    • Granular insecticide blends for soil application
    • Ready-to-use spray solutions for agro-field use

    2. Intermediates in Flame Retardant Synthesis

    Industrial manufacturers use this chemical as a phosphorus donor during the synthesis of aryl phosphate-based flame retardants for plastics and textiles. Precision in reactant charge and reaction monitoring is crucial to achieve desired polymer compatibility and thermal stability. Downstream firms demand consistent purity to ensure certification in flammability performance and avoid costly batch failures.

    Industry compliance standards

    • EN 13501 fire performance standards for construction products
    • UL 94 flammability rating for plastics and polymers
    • REACH SVHC assessment for hazardous intermediates
    • ISO 9001:2015 for quality-controlled synthesis

    Typical usage ratio

    • Phosphate loading: 10–30% wt. in masterbatch compounds
    • Input adjusted according to target limiting oxygen index (LOI) in finished resin
    • Batch-to-batch variation below 1% to meet downstream QC needs

    Downstream process integration

    • Charged into reaction vessel after temperature stabilization, often under inert gas
    • Reaction monitored for complete phosphorylation and absence of unreacted aromatic residues
    • Filtered for particulates and vacuum stripped for final purity
    • Passed through polymerization or extrusion stage into final masterbatch form

    Final product types

    • Flame-retardant polycarbonate panels
    • Fire-resistant polyester textiles
    • ABS and HIPS compounds for electronics housing
    • Non-drip treated construction foams

    3. Chemical Synthesis of Nerve Agent Standards (Analytical Reference Use)

    Analytical laboratories and certified reference material providers utilize this phosphate strictly under regulatory control as a synthetic precursor for calibration standards of organophosphate nerve agents. Synthesis involves sequential esterification and purification, with documentation and traceability meeting international forensic standards. Only authorized operators may handle or transport these reference substances.

    Industry compliance standards

    • OPCW Chemical Weapons Convention control procedures
    • ISO/IEC 17025:2017 for analytical reference material production
    • US Department of Commerce Export Administration Regulations (EAR)
    • International Air Transport Association (IATA) Dangerous Goods Regulations for shipping

    Typical usage ratio

    • Laboratory use: sub-gram to gram quantities per batch
    • Reactant charge determined by scale of CRM synthesis protocol
    • Excess neutralization required to quench unreacted material post-synthesis

    Downstream process integration

    • Charged into jacketed microreactors during controlled-esterification steps
    • All procedures conducted in negative pressure glove boxes for operator safety
    • Product isolated by preparative liquid chromatography and verified by NMR
    • Packaged under lock and documented custody chain

    Final product types

    • Certified organophosphate CRM vials for GC-MS/LC-MS trace analysis
    • Positive control kits for laboratory response testing
    • Accredited standards sent to government and defense analytical labs
    • Verification samples for inter-laboratory proficiency testing

    4. Plasticizer Intermediate for Specialty Polymer Additives

    This phosphate ester serves as an intermediate in the chemical synthesis of specialty plasticizers, particularly those tailored for high-performance vinyl and polyurethane applications. Blending and reaction chemistry demand a high degree of temperature control, and materials must pass stringent migration and volatility tests. Customers require assurance against batch contamination and consistent specification to achieve regulatory and functional compliance in plastic goods.

    Industry compliance standards

    • EU Regulation No. 10/2011 on food contact plastic materials
    • ASTM D2124 for plasticizer purity and volatility
    • California Proposition 65 chemical content declaration
    • Toy Safety Standard EN 71-3 for migration limits

    Typical usage ratio

    • Input intermediate at 10–25% relative to overall additive blend
    • Dosage modified to meet required flexibility or migration resistance in end product
    • Downstream processors adjust based on final product specification sheets

    Downstream process integration

    • Introduced during additive blending at controlled temperature for homogeneous mixing
    • Subjected to stripping and filtration to remove residual monomer and byproducts
    • Plasticizer premix injected directly into polymerization lines for in-situ modification
    • Batch tested for solubility, compatibility, and extractable profiles

    Final product types

    • Food packaging films with regulated migration limits
    • Low-volatility vinyl flooring materials
    • Toy-grade soft PVC compounds
    • Automotive interior sheeting meeting odor and emission standards
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    Certification & Compliance
    More Introduction

    O,O-Diethyl-O-(4-Nitrophenyl) Phosphate: An Experienced Manufacturer’s Perspective

    Understanding O,O-Diethyl-O-(4-Nitrophenyl) Phosphate

    Our production of O,O-Diethyl-O-(4-Nitrophenyl) Phosphate—recognized in the industry for its consistent reliability—has given us a front-row seat to the evolving needs of chemical synthesis, especially concerning advanced organophosphates. The demand for this compound centers on its reputation in research, pesticide intermediates, and a variety of organic chemistry applications. Through years of continuous batch production and direct handling, we have developed a strong perspective on where this compound delivers value, how its characteristics compare to other similar chemicals, and what end users can expect in terms of functionality, safety, and purity.

    Model and Specifications Rooted in Practice

    We supply O,O-Diethyl-O-(4-Nitrophenyl) Phosphate in multiple grades matched for common needs in agrochemical synthesis and specialty chemistry. In liquid and crystalline solid forms, the material showcases a distinct pale-yellow appearance with a mild aromatic odor—small cues that experienced technicians recognize as a sign of quality processing. Analytical testing in our in-house lab confirms each lot’s purity through methods such as HPLC and titration, aiming for purity above 99 percent, which reduces downstream rework for end users. Moisture content stays tightly controlled with routine Karl Fischer analysis. Our product reaches laboratories and production floors in tightly sealed drums or glass bottles, depending on batch size and transportation risk. Such packaging choices, often stemming from hard-learned lessons about storage sensitivity and material compatibility, support users in avoiding contamination or loss of performance.

    We face daily decisions about the correct melting point range and solubility profile. O,O-Diethyl-O-(4-Nitrophenyl) Phosphate dissolves in organic solvents like acetone and ethanol, less so in plain water. For process engineers and research chemists, this characteristic means efficient miscibility in non-aqueous reactions and reliable behavior during formulation. The yellow color, a consequence of the nitro group on the phenyl ring, becomes a visual cue for instrument calibration and tracking during synthesis—small details that speed up troubleshooting or product isolation later.

    Usage Roots and Real-World Applications

    Plant protection products continue to drive demand. Users frequently reach for O,O-Diethyl-O-(4-Nitrophenyl) Phosphate as an intermediate for insecticide platforms. It enables the construction of organophosphate-type actives. Process engineers typically report low impurity profiles and ease during phosphorization reactions when using material produced in tightly controlled, purpose-built reactors. In synthesis settings, especially where batch size and cost sensitivity matter, such a compound serves as both a reactant and a benchmark for efficiency. Researchers, especially those focused on structure-activity relationships, rely on the nitro substitution pattern since it influences both reactivity and biological function.

    Our long experience, stretching over years and dozens of product iterations, shows that this compound can also anchor analytical methods testing, especially GC/MS trace detection for environmental monitoring. Environmental labs rely on precise spiking with known standards to detect traces in water, fruit, or soil—requiring high-purity, contaminant-free product batches.

    Additional demand comes from academic laboratories, where O,O-Diethyl-O-(4-Nitrophenyl) Phosphate helps undergraduates and post-grad researchers build up knowledge in organic transformations. These teams often remark upon the manageable storage profile and relative stability compared to more reactive or volatile organophosphates, making it a practical teaching agent without continual precision refrigeration or fume-handling equipment.

    Consistency and Reliability: How Our Product Stands Apart

    There’s no one-size-fits-all in organophosphate manufacturing. Every lab and production facility brings different tolerances, regulations, and project needs. Our approach to O,O-Diethyl-O-(4-Nitrophenyl) Phosphate has always centered on removing variables, not just optimizing for cost or theoretical percent yield. Early in our operational history, we recognized that unknown byproducts—often traced back to improper control of the nitro-derivatization step—could erode customer trust or even jeopardize regulatory compliance. Technicians in our plant run regular FTIR profiling and mass spectrometry batch screening, an approach born less from corporate policy and more from old-fashioned respect for downstream users.

    We’re often asked what sets our O,O-Diethyl-O-(4-Nitrophenyl) Phosphate apart from analog phosphates or similar intermediates. In truth, the difference shows in hands-on use. Some competitors’ batches display grittiness, variable melting ranges, or odd solvent residue—all red flags for research groups and upscaling pilots. Our focus never wavers from tight reaction controls, clean separation process engineering, and regular staff retraining on batch validation work.

    In practice, that means customers see lower batch-to-batch impurity drift, fewer surprises on their first melting point test, and a smoother workflow for scale-up or industrial use. Where others might cut corners by using broader specification windows or skipping quality checks, we double down on process analytical control—small continual improvements that only someone who’s stared at clogged filtration columns or unexplained color shifts under harsh overhead lighting can truly appreciate.

    From Synthesis Bench to Shipping Container: Handling Realities

    There’s no “ideal” chemical packaging. For something as moisture-sensitive as O,O-Diethyl-O-(4-Nitrophenyl) Phosphate, years of shipping have shown us the perils of sub-par seals. Moisture pickup not only shifts the active profile but can trigger slow hydrolysis, lowering assay value before the drum even reaches its destination. That’s why our team packs with triple-seal layers, desiccant bags, and tamper-evident caps for export drums. We audit logistics partners regularly, and we don’t skimp on container testing for bulk transport.

    Thermal stability—often overlooked by traders eager to move product—plays a front-line role in our production and packaging standards. We keep temperature logs for every outbound shipment during hot seasons, flagging any spike that could risk product darkening or polymerization. Customers who receive our containers, whether for ten kilograms or a ton, report minimal “off spec” findings on arrival. That backward clarity—knowing each drum matches the last—means less time wasted on retesting and more confidence in batch production planning.

    Safety, Handling, and Worker Perspectives

    As a team that spends more shifts in the blending room than in conference calls, we notice how small details in handling can carry outsized impacts. O,O-Diethyl-O-(4-Nitrophenyl) Phosphate commands respect for its reactivity, but compared with other organophosphates, we find it less volatile and easier to manage under typical PPE protocols. Still, we train every handler on the identities and risks of aromatic nitro groups and the poisoning potential of organophosphorus materials.

    Unlike more aggressive phosphorus halides or acids, our material exhibits a slightly higher boiling point and lower volatility, giving our shift workers a small but real safety margin during open transfer steps or compounding. While this doesn't eliminate the need for extraction hoods or regular area air monitoring, it reduces the risk of unintended vapor exposure. Training our staff isn’t a regulatory checkbox—it's a matter of ensuring no worker faces a surprise from the chemistry on the line.

    We periodically update safe handling guides based on incident logs and near-miss reports from the actual line, not just regulatory codes. Any chemical plant can print out an MSDS sheet, but it’s those hard-earned operational notes—the “watch for drip-back under the condenser,” or “double-check drum tightness in the rainy months”—that keep injuries from happening. We share these details with partner labs and OEM clients because protecting hands-on workers should never stop at the factory gate.

    Environmental Responsibility and Waste Management

    Years spent overseeing wastewater effluent and handling production slurries have convinced us that conscientious production means more than hitting a target assay. O,O-Diethyl-O-(4-Nitrophenyl) Phosphate, especially at scale, can become a real environmental risk if waste streams aren’t managed tightly. Our on-site waste neutralization and two-stage scrubber systems separate organic residues, reducing the risk of downstream aquatic toxicity. Every drum of scrap or spent wash goes through controlled incineration; nothing gets dumped untreated.

    Runoff monitoring, quarterly soil sample testing, and routine air quality checks go beyond mere compliance reports. We’ve seen how overlooked trace leakage or vent mismanagement can upend production by triggering unplanned shutdowns. Over time, we’ve shifted more processes into closed reactor circuits, improving worker safety and lowering our site’s environmental footprint. Many of these improvements started as “off the clock” brainstorms among our line techs, not outside consultants.

    Advances in solvent recovery and recycling now mean that spent acetone or ethanol from O,O-Diethyl-O-(4-Nitrophenyl) Phosphate runs can often be distilled and reused, slashing both environmental risk and overhead costs. We involve every shift worker in monthly reviews and incident debriefs, reinforcing a culture of personal responsibility as much as regulatory necessity. Practical, experience-based process changes have saved us costly mishaps—not just fines, but real, measurable environmental losses.

    Regulatory Realities and Product Traceability

    In today’s chemical supply chain, regulators expect thorough documentation and lot traceability. Our system logs every batch from raw material intake to final shipment, locking in batch numbers, source amounts, and full testing data. These records helped our team resolve past customer queries about trace impurities, batch mismatches, or transport anomalies. Having this paper trail close at hand speeds up not only regulatory inspections but also rapid troubleshooting if customers ever flag an “off” batch.

    We comply with national and international registration schemes where required for export. Each compliance review gives us another chance to find process weak points and close out any ambiguity in batch reporting or labeling. Labs conducting sensitive toxicological research or environmental screening need confidence that the product in their hands aligns exactly with product spec and batch trace results. Supply chain transparency, built from the ground up, gives both us and our clients the confidence to push ahead with demanding projects.

    Why Product Differences Matter: Technical and Economic Realities

    Our perspective isn’t shaped by a lab manual—it’s built from actually running syntheses day in and out. O,O-Diethyl-O-(4-Nitrophenyl) Phosphate often gets compared to other organophosphates by function or price. Every replacement or alternative carries its own tradeoffs. Substituting with monoethyl or dimethyl analogs can shift reactivity, raising or lowering the required input under otherwise identical reaction conditions. Poorly controlled nitro substitutions invite unpredictable side product formation; blending errors or unrecognized solvent residues can trigger operator headaches during filtration or post-reaction cleanup.

    Material produced on smaller, manual lines often comes with batch drift: little color variations, unpredictable melting points, and worse GC purity. We have spent years tightening process controls, not for marketing claims, but to avoid those costly “fishing expeditions” downstream users face when unexpected peaks show up in product monitoring.

    Technical service feedback from long-term clients tells us the story: consistent lots mean fewer failed production runs, less downtime, and tighter cost controls. Even slight differences in solubility, crystal size, or by-product levels impact both laboratory and industrial workflows—details impossible to grasp without hands-on process engagement.

    Where some suppliers focus only on price points, we keep our eye on performance realities—how a slightly off-grade batch ripples through entire syntheses, from extra purification steps to delayed shipments and cash flow crunches for customers. Technical teams that test our material repeatedly highlight the reliability in color, impurity levels, and solvent residue—practical proof that experience-led production pays off.

    Continuous Improvement Driven by Real-World Feedback

    Every serious manufacturer must stay humble in the face of unexpected plant events—pump failures, raw material shifts, or new environmental rules. We set aside monthly time to review root-cause reports, adjust quality protocols, and crowdsource feedback from frontline operators. The best process innovations come from those who face the chemistry up close: knowing when to swap filter media, which column resin outperforms last year’s model, or when an uptick in summer humidity signals a storage risk.

    Long-term supply relationships depend less on contracts and more on quiet, evidence-based improvements that solve real challenges. Our history with O,O-Diethyl-O-(4-Nitrophenyl) Phosphate stands as a series of practical fixes—improving filter screenings, adjusting recrystallization timing, investing in modern testing platforms—each one born from having to solve an actual problem on the plant floor or in a customer’s lab.

    Long dialogues with technical buyers give us a window into emerging needs, like greater analytical traceability, better packaging for repeated sampling, or tuning product grade for new synthetic targets. Each request pushes us to revisit the basics: rethink solvent handling, improve staff training, or tweak the specifications of incoming raw materials. Our culture values practical adaptation as highly as theoretical chemistry.

    Looking Ahead: Challenges and Opportunities

    Chemical manufacturing never rides a straight line. New environmental restrictions, rising raw material prices, or shifting end-user preferences force experienced producers to rethink processes and priorities. O,O-Diethyl-O-(4-Nitrophenyl) Phosphate remains a mainstay for research, synthesis, and industrial use, but tighter controls on organophosphates mean we always have to anticipate not just client specifications, but evolving regulatory and safety mandates.

    We invest in green chemistry principles—seeking solvent swaps, energy reduction, and waste recycling—while keeping core product performance front and center. Every improvement traces back to years of practical experience handling not just successes, but the moments when equipment breakdowns, test failures, or supply chain hiccups forced us to innovate on the fly.

    Future opportunities lie in further customizing batch size, purity, and solvent profiles for research or formulation tasks neither we nor our customers had imagined even a few years ago. As a manufacturer, our role stands as more than just supplying a commodity chemical: we provide reliability, technical expertise, and a century’s worth of practical experience boiled down into each drum that leaves our loading dock.