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O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate

    • Product Name O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate
    • Alias Bromophos
    • Einecs 252-233-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    314523

    chemical_name O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate
    molecular_formula C10H12BrCl2O3PS
    appearance Colorless to light yellow liquid
    solubility Insoluble in water, soluble in organic solvents
    cas_number 15585-00-3
    density 1.56 g/cm³ (approximate)
    usage Primarily used as a pesticide (insecticide)
    flash_point Above 100°C (typical for similar organophosphates)
    refractive_index 1.554 (at 20°C, approximate)
    storage_conditions Store in a cool, dry, and well-ventilated area

    As an accredited O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A sealed amber glass bottle containing 100 grams, labeled with hazard symbols and chemical name: O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate.
    Shipping The chemical **O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate** is shipped in accordance with international hazardous material regulations. It is packed in tightly sealed, chemical-resistant containers within secondary containment, labeled with appropriate hazard markings, and accompanied by safety documentation. Transport is handled by certified carriers to ensure safety and regulatory compliance.
    Storage O,O-Diethyl-O-(4-Bromo-2,5-dichlorophenyl) phosphorothioate should be stored in a cool, dry, and well-ventilated area, away from heat sources, open flames, and direct sunlight. Keep the container tightly closed and clearly labeled. Store separately from incompatible materials such as strong oxidizers and bases. Use suitable, chemical-resistant containers, and ensure access is limited to trained personnel with appropriate protective equipment.
    Application of O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate

    Applications of O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate in Industrial Manufacturing

    O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate is an organophosphorus compound widely recognized for its effectiveness as a specialty agrochemical intermediate. Its chemical properties support high-purity requirements and precise synthesis control in regulated industrial production streams. As a direct manufacturer, we support numerous downstream sectors by supplying consistently high-grade material, fully documented for auditable traceability and batch-specific compliance. Applications below represent verified industry pathways where this material functions as a key active or precursor in large-scale manufacturing.

    1. Insecticide Technical Manufacturing

    In the agrochemical industry, this phosphorothioate molecule constitutes a primary active intermediate in the production of organophosphate insecticides targeting piercing and sucking pests in cotton, rice, and horticultural crops. Technical compound synthesis requires strict adherence to purity thresholds, as regulated by agricultural use authorities, to ensure product registration and field performance. Material enters the production sequence during active substance synthesis prior to final formulation into dispersible concentrates or emulsifiable concentrates. Quality assurance focuses on isomeric content and low threshold levels of related impurities, verified batch-wise via HPLC and GC methods.

    Industry compliance standards

    • FAO/WHO Specification for Pesticides (JMPS)
    • China National Food Safety Standard for Pesticide Residues (GB 2763)
    • EU Plant Protection Product Regulation (EC) No 1107/2009
    • Good Manufacturing Practice for Pesticide Active Ingredients (ISO 9001:2015, ISO 14001:2015)

    Typical usage ratio

    • 85–95% by weight in technical-grade active production; adjusted according to target impurity profile and formulation requirements.

    Downstream process integration

    • Introduced during esterification and phosphorothioate substitution reactions in active ingredient synthesis lines.

    Final product types

    • Technical concentrate for insecticides
    • Water-dispersible granules
    • Emulsifiable concentrate insecticides
    • Microencapsulated pest control formulations

    2. Synthesis of Veterinary Ectoparasiticides

    Pharmaceutical-grade phosphorothioates derived from this raw material are essential in the formulation of veterinary ectoparasiticides targeting livestock ectoparasites, such as ticks, mites, and lice. These end products must meet strict pharmacopoeial monographs and residue limits in animal-derived food products. Input concentration is controlled based on species-specific efficacy tests and stability trials. The raw material enters post-extraction basic synthesis for active pharmaceutical ingredient development before downstream blending and dosage form conversion, such as pour-ons and sprays.

    Industry compliance standards

    • Veterinary Pharmacopoeia of the People’s Republic of China (2020 edition)
    • EMA Maximum Residue Limits (MRL) for Veterinary Medicinal Products
    • VICH GL42 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • EU Regulation (EC) No 726/2004 for Animal Health Products

    Typical usage ratio

    • 40–55% in API synthesis batches, adjusted per stability and bioavailability studies for each animal species.

    Downstream process integration

    • Used in the controlled phosphorylation step during veterinary API synthesis; followed by purification and micronization before formulation into finished ectoparasiticide forms.

    Final product types

    • Veterinary pour-on ectoparasiticides
    • Oral and injectable antiparasitic preparations
    • Livestock dips and sprays
    • External spot-on treatments

    3. Intermediate for Custom Agrochemical Synthesis

    Contract synthesis operations within the agrochemical sector utilize this compound as a key intermediate for structural modification and development of new proprietary actives. R&D and toll manufacturing clients specify analytical grade quality and trace-level impurity certification according to the final registration market. Material introduction takes place in early-stage reaction schemes requiring tightly controlled stoichiometry and temperature monitoring to direct selectivity. Documentation includes manufacturing batch records, COA, and full traceability chain for regulatory submission.

    Industry compliance standards

    • OECD Principles of Good Laboratory Practice (GLP; ENV/MC/CHEM(98)17)
    • ISO 17025 Accreditation for Analytical Testing
    • REACH Regulation (EC) No 1907/2006 for registered intermediates

    Typical usage ratio

    • 25–60% by molar ratio, selected per one-pot or staged synthesis processes to balance yield and conversion efficiency.

    Downstream process integration

    • Charged during initial ring-substitution or phosphorylation steps in proprietary molecule custom synthesis lines; residuals quantified for reaction mapping.

    Final product types

    • Registered new active ingredients (NAIs)
    • Experimental agrochemical molecules
    • Custom pesticide building blocks
    • Advanced synthetic intermediates for further downstream conversion

    4. Research-Grade Analytical Reagent Supply

    Academic, governmental, and contract research laboratories require consistent high-purity batches of this material to support method development for pesticide residue quantitation, mechanism of action studies, and environmental fate investigations. Synthesis batches for this application undergo additional chromatographic refining, along with stringent assay and impurity profiling per research specifications. The reagent integrates into chemical standards preparation, validation batch productions, and spiking studies for method accreditation.

    Industry compliance standards

    • ISO 17034 Reference Material Producer Accreditation
    • ISO/IEC 17025 Laboratory Management Systems
    • GLP (21 CFR Part 58, OECD GLP)

    Typical usage ratio

    • 10–99.5% in analytical reference standard production; precise ratio set per required working concentration and matrix.

    Downstream process integration

    • Applied during analytical reference material compounding, calibration solution preparation, and inter-laboratory proficiency test kit formulation.

    Final product types

    • Pesticide analytical standards
    • Environmental monitoring reference samples
    • LC-MS/MS and GC-MS calibration materials
    • Certified matrix-matched control samples
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    Certification & Compliance
    More Introduction

    O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate: Manufacturer's Perspective

    Understanding Our Role: Years of Chemical Craftsmanship

    Working with specialty organophosphates demands skill, patience, and sharp attention to detail. At every stage of the manufacturing process, our team has spent years developing, refining, and optimizing production of O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate. As the original producer, our relationship with this compound stretches from the research bench to the industrial reactor. Hands-on experience with real-world batches informs our approach far more than any generic documentation ever could.

    Our process control operators, synthesis chemists, and quality engineers don't just follow procedures—they shape them to deliver consistent results batch after batch. The reality of maintaining yield, minimizing side reactions, optimizing impurity profiles, and reducing waste lies at the heart of our daily routines. The routine never stays routine in organophosphate manufacture: equipment configuration, raw material freshness, and scale all can nudge a process outside its comfort zone. Being the manufacturer means we adapt dynamically, based on lessons from each campaign.

    Getting the Basics Right: Model and Specifications From the Source

    This compound, O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate, often known in industry circles for its role in advanced crop protection, comes with exacting standards that only direct production control can ensure. Most of what circulates in the market begins here, with our reaction vessels, yield optimizations, and purity checks. Years on the line inform us what to watch for: residual solvents, tricky diastereomer formations, and minor halogen impurities can all signal trouble. We run each lot through extensive GC and HPLC testing. Only those lots that meet our target purity—typically above 98%—move forward to packing.

    We work to exact mass balances. The melting point range remains a direct indicator of batch quality; if a batch slips outside typical ranges, our chemists know to go back to troubleshooting immediately. Manufacturers see problems as soon as they arise, while resellers and distributors only see specifications on a document. Through all of this, direct oversight allows us to catch and address subtle issues, like unusual off-white tinges or humidity sensitivity, before products ever leave our site.

    Direct Production Insights: How Scale and Controls Impact Outcome

    Scaling from a laboratory flask to a full-kettle operation never occurs with a casual flip of a switch. Each increment in scale comes with new heat transfer problems, uneven mixing, and the risk of runaway exotherms. By handling these shifts directly, we sustain quality—something that cannot be tracked from a distance. Real operators know the sound and look of a healthy reaction, and quick adjustments in feed rates or reflux can head off catastrophe.

    We use exclusively inspected and certified raw materials. Sourcing the diethylphosphorothioate chain and the bromo-dichlorophenyl starting base requires proven suppliers. Even slight off-grade materials can introduce impurities into the final product profile, which down the line might affect product performance in the field. Our analytical team runs NMR and IR on both intermediates and final batches, documenting trace elements often missed by outside labs. This hands-on QC doesn’t end at the lab—our bulk storage and container cleaning processes keep residual cross-contamination in check.

    Why Users Rely on Direct Manufacturing Know-How

    Clients—especially formulators—reach out early for technical clarification. The reliability of O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate depends on molecular-level precision. Unwanted isomers, process byproducts, or excess solvent residues can all interfere with microencapsulation and controlled-release applications. Having full traceability right down to the original batch records allows us to troubleshoot any field complaints with direct evidence rather than assumptions or guesswork.

    Our plant’s record-keeping provides a transparent data trail, and this confidence earns trust with regulatory consultants and integrators alike. One frequent concern from new users relates to shelf-life and long-term stability in various climates. Controlled climate chamber studies run in-house have given us unique insight into optimal storage conditions, container compatibility, and best-practice handling. We can pinpoint shifts in physical appearance or assay over periods exceeding twelve months, knowledge gained only by holding product over time and testing real-world outcomes.

    Application Focus: Uses in Crop Protection and Beyond

    Decades spent in synthesis and technical support revealed the best-fit use cases. Primarily this organophosphate plays a role in insecticidal formulations. Agrochemical development teams value stable active ingredient content and predictability through different formulation technologies—emulsifiable concentrates, wettable powders, or microcapsules. Formulations with O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate demand exacting particle size and consistent dispersion behavior. These considerations only become visible after years immersed in formulation work, not at the bulk level.

    In specialty research, we see creative applications emerge—vector control, public health projects, and specific veterinary needs, all depending not only on compound availability but on batch-to-batch confidence. Direct manufacturer support means we can discuss analytical data openly, adjust supply chain forecasts, and help end-users avoid pitfalls such as product liquefaction under certain temperature/humidity conditions.

    Distinctions from Alternative Compounds: Why Precision Synthesis Matters

    Alternative organophosphates exist, and each manufacturer recognizes the subtle chemical relationships that distinguish one molecule’s utility from another’s. In synthetic chemistry, small changes in substitution pattern or alkyl chain length shift the profile from highly effective to troublesome. O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate at this exact halogenation pattern balances volatility, solubility, and environmental profile in a way few analogs can replicate.

    Manufacturers have firsthand experience with consequences of impurity. Compounds with incomplete bromination or excess dichloro substitution generate noncompliant residues, cause clogged injectors in formulation lines, or create handling hazards not visible at the analytical scale. Over the years, we learned that proper stoichiometry, controlled addition speeds, and post-reaction workup greatly reduce formation of unwanted byproducts. End-users ultimately see these benefits through smoother blends, clear solution preparation, and longer shelf-life.

    Meeting Technical Demands: Fine-Tuning for Real-World Performance

    Field performance links closely to the control we hold over inherent product properties. By steering the synthesis through controlled reaction kinetics, careful crystallization, and tightly managed drying cycles, we prevent agglomeration and improve downstream processability. Our operators remain on alert for signs of product sticking, excessive flow resistance during packing, or odor anomalies—all markers of product that can negatively impact end-use.

    We also invest in stability testing—humidity chambers, temperature cycling, and UV exposure—all factors that shift over a product's life in global supply chains. Our knowledge doesn’t end at the factory gate. Feedback from downstream partners on crop performance, formulation compatibility, and even local warehousing has prompted process improvements. This loop from field and customer plant, back to our reactor logs and, finally, our continuous improvement meetings, closes only through full manufacturing control.

    Safe Handling and Environmental Considerations: Practical Knowledge From the Factory Floor

    Responsible stewardship forms part of our daily routine. We train our teams on proper containment, using dust extraction and spill management practices that go beyond baseline recommendations. Experience has shown us that improper drum filling, especially at high humidity, leads to clumping and product loss. Our in-plant policies, developed through rigor and experience, have improved both worker safety and downstream usability.

    Sustainability initiatives also drive our product responsibility. Manufacturing organophosphates presents unique disposal and environmental concerns. We invest in solvent recovery, waste minimization, and emission control systems specific to halogenated phosphorothioates. Any byproduct incineration or neutralization is monitored continuously, and our long relationships with regional regulators and environmental auditors keep our production both compliant and reliable.

    As a plant operator, you see beyond the datasheet promises. Disposal headaches, container residues, and groundwater risk all arise from the real world, not theory. Over time, we've integrated practical steps such as batch residue monitoring, improved drum sealing, and on-site water treatment to prevent downstream headaches for users and neighbors alike. Direct stewardship at the source, not delegated to third parties, shapes responsible chemical manufacturing.

    Supporting Research and Development: Open Data From the Lab Bench

    Chemists at the application development stage frequently approach us for primary analytical standards and insight on edge-case scenarios. We open our batch records and analytical archives, showing trace impurities, minor spectral peaks, and early degradation signs. This transparency aids R&D teams in quickly identifying interactions with adjuvants or unusual storage conditions that might not surface for years under normal distribution.

    Our own R&D crosses into fields like microencapsulation, wetting agent compatibility, and slow-release granule formulation. We push for clean reactions with minimal solvent residues—something only seen by those who synthesize at scale, not those moving jugs on paper. Testing new process conditions, tweaking crystal forms, and experimenting with purification yields direct benefits for customers facing novel formulation hurdles. When a new type of dispersant, packaging film, or blending tank gets introduced at an end-user site, we offer direct feedback because our knowledge springs from actual bench and plant experience instead of guesswork.

    Quality Control: Lessons From Decades of Continuous Improvement

    Inspection teams at a manufacturing site develop instincts that no outsourced laboratory can replicate. By observing color gradations, subtle odor shifts, or crystal inconsistencies, they anticipate shipping issues and provide early warnings. Pattern recognition across dozens of campaigns means small deviation signals rarely go unnoticed. Every batch of O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate we ship reflects collective vigilance and corrective action—whether it's adjusting a filter drying step, recalibrating an analytical instrument, or retraining an operator on weighing technique.

    These embedded lessons have helped us drive defect rates down and increase traceability. Introducing batch-specific QR code systems allowed us to trace any complaint right back to the exact vessel, shift, and operator. This level of accountability distinguishes the manufacturing seat from those only passing through inventory.

    Addressing Market and Regulatory Trends: Staying Ahead Through Experience

    The agrochemical landscape never remains still. New regulations, shifting limits on halogen residues, and evolving import controls shape the demands on production, often at short notice. Being nimble as a manufacturer, we respond to these shifts by tweaking our reactor cleaning schedules, adopting lower-residue precursors, or instituting full chain-of-custody protocols. Years of navigating regulatory audits and customer-site reviews taught us which documentation satisfies, which procedures fall short, and how to preempt common audit flags.

    We support audits not with boilerplate certificates, but with field-worn logbooks, clear deviation explanations, and real samples drawn directly from production. This openness both reassures partners and helps us adapt more quickly than specifications-only suppliers. We keep a working dialogue with industry associations and standard-setting bodies so that we are never caught flat-footed by new international requirements.

    Building for the Future: Training, Investment, and Knowledge Transfer

    Knowledge doesn’t reside in machines. Our people carry the insight needed to run complex phosphorus chemistry reactions well and reliably. Onboarding new technicians into our production process involves shadowing seasoned operators, hands-on troubleshooting, and detailed training on critical control points. This expertise doesn’t come from manuals or outside consultants: it builds from years spent watching successful and failed campaigns.

    We reinvest in both technology and people. Reactor upgrades, new sensors, and advanced analytics now supplement operator judgment, not replace it. By maintaining a workplace culture that respects attention to detail and rewards proactive problem-solving, we ensure O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate continues meeting demand long into the future. Lessons pass from shift to shift, season to season, plant to plant, echoing through each product we ship.

    Technical Support: From Our Bench to Your Operation

    Our engineers and technical support specialists frequently visit customer facilities to help optimize end-use formulations. Understanding firsthand how changes in viscosity, pH, or minor impurity levels affect finished product performance proves invaluable. By directly supporting calibration, tank cleanout, and blending operations onsite, we catch potential problems before they turn into losses.

    Questions from customers never fall on deaf ears. As hands-on producers, we appreciate the importance of rapid, transparent technical answers—whether it’s fine-tuning dispersants, troubleshooting filtration, or interpreting a regulatory report on batch trace residues. Offering this level of immediate, evidence-based support keeps production lines moving and customers confident.

    What Sets Factory-Direct Supply Apart: Closer to the Chemistry

    Dealing directly with a manufacturer means your supply chain rests on people who know the product’s creation from start to finish. We control scheduling, logistics, and quality in a way that distance middlemen can never duplicate. Immediate access to blending notes, raw material certificates, and full shift logs helps pre-empt supply chain disruptions and smooths out global variabilities.

    Our commitment: every lot of O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate carries not just a regulatory file, but a story—a record of controlled steps, precise intervention, and hands-on monitoring. Whether the product lands in a research lab or a 20,000-liter blending tank, buyers benefit from the direct transfer of knowledge, accountability, and ongoing improvement that only the primary producer can guarantee.

    Looking Ahead: Partnership Built on Knowledge and Real-World Results

    Through decades of hands-on manufacturing, we have learned that quality outcomes depend not only on formula and process, but on collaboration with users. Many innovations, process tweaks, and risk mitigation strategies have grown from honest, frank discussions between our plant engineers and the scientists or operators who rely on us. By grounding every drum, bottle, and bulk shipment in this open, consistent effort, we aim to keep O,O-Diethyl-O-(4-Bromo-2,5-Dichlorophenyl) Phosphorothioate at the forefront of reliability, performance, and safety.

    From our reactors to your application, every step strengthens the end result. We measure our success not by tons shipped, but by batches done right—with transparency, technical rigor, and dedication to driving positive outcomes in the field and beyond. This day-to-day investment shapes a future of chemical manufacturing where experience, evidence, and trust work hand in hand.