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O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)Formaldoxime

    • Product Name O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)Formaldoxime
    • Alias Aldicarb
    • Einecs 258-887-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    211237

    Chemical_Name O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)Formaldoxime
    Molecular_Formula C6H13N3O3S
    Molecular_Weight 207.25 g/mol
    CAS_Number 52836-63-2
    Appearance White to off-white solid
    Solubility_in_Water Slightly soluble
    Boiling_Point Decomposes before boiling
    Storage_Conditions Store in a cool, dry place, away from incompatible substances
    Chemical_Class Oxime carbamate
    Synonyms Methomyl oxime, Dimethomorph oxime derivative
    Stability Stable under recommended storage conditions
    Hazard_Statements Toxic if swallowed, harmful to aquatic life
    Purity Typically >98% (for laboratory reagents)

    As an accredited O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)Formaldoxime factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 100 grams; tightly sealed with a tamper-evident cap, labeled with chemical name, hazard pictograms, and handling instructions.
    Shipping **Shipping Description:** O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)Formaldoxime should be shipped in tightly sealed containers, protected from heat and moisture. The chemical must be labeled according to hazardous materials regulations. Use appropriate secondary containment and cushioning. Shipping should comply with local, national, and international regulations for toxic and potentially hazardous chemicals.
    Storage O-(Methylcarbamoyl)-1-dimethylcarbamoyl-1-(methylthio)formaldoxime should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers. Protect from direct sunlight, moisture, and sources of ignition. Ensure proper labeling and access control to authorized personnel only. Use secondary containment to prevent environmental contamination in case of leaks or spills.
    Application of O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)Formaldoxime

    Applications of O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)Formaldoxime in Industrial Manufacturing

    As a manufacturer specialized in advanced chemical intermediates, we supply O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)Formaldoxime to leading industrial clients who rely on its unique molecular functionality. This compound serves as a critical synthetic intermediate for various regulated applications in agrochemical, pharmaceutical synthesis, specialty biocides, and fine chemical production. Below we outline its precise, real-world integration into established downstream sectors.

    1. Agrochemical Synthesis: Active Ingredient for Carbamate Pesticides

    This intermediate enters directly into the last stages of synthesis for certain carbamate-based insecticides, where reactivity of methylthio and dimethylcarbamoyl moieties is key for constructing diverse active ingredients. Its controlled addition supports the targeted molecular assembly required for registered agricultural chemicals, ensuring product traceability from raw material to formulated crop protection agent.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 9001:2015 Quality Management for Agrochemicals
    • Regulation (EC) No 1107/2009 on Plant Protection Products
    • China GB 2763-2021 Maximum Residue Limits for Pesticides

    Typical usage ratio

    • Active intermediate input ranges from 15-25% mass fraction in the precursor coupling step, adjusted by target pesticide structure and batch scale. Process engineers modify proportion to balance yield and purity against residual unreacted intermediates.

    Downstream process integration

    • Reaction stage: Our material feeds into condensation and cyclization reactions after preliminary raw purification, requiring nitrogen inerting and precise pH control; product isolation follows with direct filtration and solvent stripping before formulation into technical concentrate.

    Final product types

    • Technical-grade carbamate insecticide (e.g., methomyl, oxamyl technical)
    • Emulsifiable concentrates for crop spraying
    • Water-dispersible granules (WDG) for field application
    • Seed treatment solutions complying with registered MRLs

    2. Pharmaceutical Intermediate: Synthesis of API Precursors

    In pharmaceutical manufacturing, downstream companies use this compound in active pharmaceutical ingredient (API) intermediate routes, specifically for constructing oxime-linked molecular fragments found in several CNS-active drugs and antiparasitic agents. It serves both as a reactant for selective N-alkylation steps and as a precursor for further protective group chemistry, allowing production under current Good Manufacturing Practice requirements.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP–NF and EP monograph guidelines for intermediate controls
    • U.S. FDA 21 CFR Parts 210/211 (cGMP for Finished Pharmaceuticals)
    • EU EudraLex Volume 4 GMP Guidelines

    Typical usage ratio

    • Intermediate introduced at 8-12 mol% relative to target API batch, controlled via in-process HPLC tracking. Higher-end ratios for multi-step alkylation; precise stoichiometry critical for downstream impurity control in GMP synthesis.

    Downstream process integration

    • Mid-synthesis: Material is charged during batch-wise N-alkylation and oximation, typically after initial aromatic substitution but before final deprotection. Reactors equipped with multi-stage liquid–liquid extraction to ensure removal of unreacted intermediate and byproducts; subsequent distillation purifies the API precursor.

    Final product types

    • Active pharmaceutical ingredient intermediates for CNS and antihelminthic drug classes
    • Bulk API (pre-final crystallization)
    • Chemical reference standards for impurity profiling
    • Contract manufactured intermediates for global pharma firms

    3. Specialty Biocides: Synthesis of Industrial Preservative Agents

    Selected specialty chemical producers incorporate this formaldehyde-oxime derivative as a core constituent in biocidal formulations, where its reactivity enables coupling with carrier molecules to produce next-generation industrial preservatives targeting microbial contamination in paints, adhesives, and coatings. Downstream application requires stringent compliance with hazardous substance controls given biocide classification.

    Industry compliance standards

    • EU Biocidal Products Regulation (BPR, Regulation (EU) No 528/2012)
    • U.S. EPA FIFRA Registration Requirements
    • ISO 14001:2015 Environmental Management Systems
    • Japan CSCL (Chemical Substances Control Law) for biocides

    Typical usage ratio

    • Input typically at 4-7% by weight in synthesis of preservative active; batch-specific adjustment based on targeted MIC (minimum inhibitory concentration) for end formulations. Inclusion rates modified according to regulatory substance restrictions and performance testing in the end-use matrix.

    Downstream process integration

    • Pre-dispersion and reaction with carrier oligomers in stainless steel reactors; followed by stabilization under controlled temperature to achieve the desired antimicrobial spectrum. Final material isolated and standardized before blending into downstream product formulations at customer manufacturing sites.

    Final product types

    • Industrial paint preservatives
    • Adhesive and sealant biocide concentrates
    • Water-based industrial coatings preservatives
    • Bulk biocidal additives for construction materials

    4. Fine Chemical Synthesis: Precursor for Heterocyclic Compounds

    Producers in the fine chemical sector utilize this compound to introduce methylcarbamoyl and methylthio functional groups during synthesis of heterocyclic intermediates used in dyes, electronic chemicals, and customized molecular scaffolds. Reaction reliability and purity drive procurement for these sensitive downstream processes, which often operate under strict batch-tracking and material audit protocols.

    Industry compliance standards

    • REACH Registration, Evaluation, Authorization and Restriction of Chemicals (Europe)
    • ISO 9001:2015 for quality traceability
    • GHS (Global Harmonized System) for labeling and transport
    • JIS (Japanese Industrial Standards) for specialty organics

    Typical usage ratio

    • Raw input at 11-17% of batch mass, ratio adjusted after pilot synthesis to accommodate reactivity of feedstock and product yield demands; fine chemical producers may increase dosage to enhance heterocyclic ring closure rates depending on downstream coupling requirements.

    Downstream process integration

    • Intermediate enters ring formation or derivatization step after oxidation or reduction pre-treatment; reaction temperature and solvent profile tailored to achieve correct stereochemistry. Finished intermediate isolated via fractional crystallization and purity validated by NMR/GC-MS before shipment.

    Final product types

    • Functionalized heterocyclic intermediates for dye manufacturing
    • Electronic material building blocks
    • Precursors for catalyst ligands
    • Custom molecular fragments for contract research customers
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    Certification & Compliance
    More Introduction

    O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)Formaldoxime: Built For Reliable Results

    Trusting the Process – Why Careful Synthesis Matters

    Drawing from years on the production floor, I’ve learned the difference between a batch that just meets purity benchmarks and one that truly holds up in demanding conditions. Producing O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)formaldoxime (also known as methomyl oxime, though the name can vary by application), my team faces hard lessons about cleanliness, precise measurement, and reaction control. Customers using this compound count on tight reproducibility, not just “close enough” parameters, and I see the value in rigorous raw material screening, proper vessel preparation, and diligent temperature tracking. Even a small deviation can impact downstream usage—especially for people in crop protection, synthesis of intermediates, or specialized research.

    We invest in accurate calibration for metering pumps and temperature control gear. Our operators work in a way that supports repeatability: following written procedures, recording every batch variable, and sampling at checkpoints. The goal isn’t just to hit spec, but to deliver a product predictable every run, whether in a drum or a tanker. Our lines run with this focus, and experience shows that careful planning early prevents headaches down the line.

    Model and Specification: Facts That Guide Us

    O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)formaldoxime never passes as a commodity in our plant. Ours comes as a white to faintly off-white crystalline powder, sometimes, in larger batches, with a hint of yellow depending on trace impurities in starting materials. Melt point targets range from 77 to 79°C, and standard purity clocks in above 98%, based on GC area percent after careful drying. We never ship it with more than 0.5% water by Karl Fischer titration, because even small excess moisture gives users storage challenges and trouble in reactions if this material serves as an intermediate.

    Some partners ask for a coarser or finer grind, and we calibrate our mills based on their technical requirements. One batch might move into solution formation, another straight into solid blends. We test for stability under recommended warehouse conditions, and stack drums two-high with clear labeling for date and lot. During packing, we avoid static charge buildup, since this molecule can show sensitivity to friction and fine dust. Years of hands-on experience shape these habits—products like this reward careful handling much more than other similar substances we make.

    Application in Crop Protection and Synthesis

    O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)formaldoxime found its core customer base in the agricultural sector, at first, where it acts as a precursor in pesticide synthesis. Our partners in formulation regard it for its consistency and known reactivity profile. Minor side impurities, even under the threshold of detectability, can trip up highly sensitive downstream processing. We prepare every batch with this in mind, running series of pilot tests to be sure everything behaves as expected when scaled up.

    Beyond agriculture, it also fits into fine chemical synthesis pathways, usually as a carbamoylation agent or key oxidizable intermediate. Researchers occasionally ask us about solvent compatibility, shelf stability, and safe scale-up, and we share what we’ve seen in production. The product needs inert storage conditions, temperature control, and a dry workspace—recommendations we back up with stories of how even small missteps can cost time and money in research or plant-scale work. Partnering directly with end users, we adjust particle size, purity stringency, and suggest best handling practices so their process avoids hiccups.

    Experienced Hands See the Differences

    People often ask, “How is this different from other related carbamoyl oximes?” Here’s the hard-won answer. The dual carbamoyl groups and the methylthio substituent give O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)formaldoxime particular value in selective synthesis. Labs working with single-carbamoyl analogues notice greater side reactions or less stability during prolonged storage. Our version retains shelf life and resists slow degradation, even in environments where temperature control isn’t perfect. We also see higher solubility in select organic solvents compared to older generation oximes, based on side-by-side solubility measurements in our lab. This matters for partners using automated dosing or dispersion.

    Other similar-structured products sometimes fail when exposed to light, or react too quickly to base or acid, making them impractical at scale or for shipping long distances. Over many production lots, we observed that this molecule stands up to routine factory handling and storage demands better than others in its chemical class. That reliability creates value for formulators, who may run small or large batches based on seasonal need. What sounds like a minor difference in structure can change the process cost and the stress level on the line.

    Transparency in Quality and Traceability

    Every plant manager and process chemist we meet asks tough questions about quality and traceability. They should. We build traceability into every step, issuing unique lot numbers, storing retain samples, and documenting raw material origins. Any deviation from normal—whether a shift in melting point, slight change in color, or off-odor—raises a flag. We share full analysis certificates with partners. Years ago, a partner traced a stalled synthesis to a tiny overage of lower-boiling impurity. Our response was to pull the batch, test all related production tanks, and invest in better purification hardware. These lessons shape our quality systems still.

    No one wants guesswork with a product like this, especially when downstream applications demand tight tolerances. We run QA labs on-shift, so any variation can be caught before packing. Regular audits, by customers and our own internal teams, drive continuous improvements. We believe that people making daily decisions—about which batch to run, when to pack, how tight to set final filtration—should see this product as a working partnership, never a black box.

    Practical Handling, Safety, and Storage

    Field experience shows that O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)formaldoxime behaves as you’d expect for a strong-acting oxime: stable but not indestructible. Municipal regulation requires proper labeling and spill planning. Employees wear gloves, goggles, and utilize dust collection measures. In our storage areas, we keep it in drums with gasketed lids and silica packs to control moisture. Heat, sparks, and open flame stay far from the warehouse, with clear signage and frequent training—a routine that’s served us well through years of safe operation.

    Waste treatment poses challenges in some regions, as some byproducts fall under stricter regulatory rules. We run on-site neutralization and solvent recovery, minimizing plant discharge. Partner companies frequently visit to audit our protocols, and we update our practices as environmental standards grow stricter. As regulations shift and evolve, we stay ahead by tracking rules globally, using only upstream providers with robust traceability and certification. We also support partners with guidance as regulations tighten, rather than passing along materials that risk compliance issues.

    Addressing Industry Challenges and Solutions

    Working with O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)formaldoxime, we’ve come across challenges that the industry rarely broadcasts. Shipment in humid climates often leads to caking, raising headaches for end users. To address that, we switched to double-layer polyethylene bag lining, vacuum-sealed before drum fill and nitrogen flushed on export cargo. Several seasons ago, this step alone cut caking complaints to almost zero, and we heard directly from purchasing teams relieved to see dry, free-flowing powder at delivery.

    Another persistent problem came from slow dissolution. Coarser grades resisted making uniform solutions in fast cycles. Our R&D team changed our grinding method, reducing oversized granule formation and blending batches in temperature-controlled rooms. Real-world testing in user facilities gave us feedback cycles faster than any in-house simulation. The changes improved usability and customer feedback strongly reflected that.

    Supply chain interruptions, particularly in recent global health crises, forced us to localize some raw material sourcing. We built redundancy across two certified suppliers, avoiding dependency on any single upstream source. Production lines now keep extra stock buffers. With two audited vendors, we weathered disruptions that closed ports and interrupted normal cargo movement elsewhere. People using our products felt less impact, and loyalty grew as a result of that preparation.

    Documentation, while paperwork heavy, remains a point of pride for us. Safety data, batch histories, and validation reports travel with each order, often by encrypted digital means and in tamper-proof sealed folders. The intent is to help customers through customs checks and regulatory filings, making their life easier, not just checking boxes for compliance.

    Continuous Improvement and Investment

    No manufacturer is immune to mistakes, but ongoing investment solves or prevents the same problems spreading. We put quality improvement at the center of factory expansion. Regular upgrades to filtration, material handling, and packaging systems address both worker safety and absolute product uniformity. Operators who have worked here for decades teach new hires what to watch for: a change in odor, dust on the drum rim, slower than usual filtration speed—these tiny cues point to bigger issues if ignored.

    As new analytical gear comes to market, we bring it into our quality lab. Gas chromatographs get recalibrated every quarter, and reference material is purchased from two separate internationally-certified labs. When we saw slower customs clearance on some export lanes, we started including multi-language technical information sheets and expanded 24/7 support to answer overseas inquiries. The aim is always predictable delivery and peace of mind for the technical staff depending on our shipments.

    Close relationships between our plant R&D and customers mean changes move fast from lab bench to full-scale line. If feedback singles out a pain point—say, slow release in formulation, or less than expected performance in field trials—we task engineers to trace causes, verify solutions, and keep buyers in the loop the whole way. We value frank customer conversations, seeing them as part of long-term mutual improvement.

    Supporting Honest and Reliable Supply Chains

    We see fake or misrepresented products enter markets all too regularly. As a direct manufacturer, we counter this by uniquely marking shipments, using both physical and digital trace codes. End users can verify origin by contacting us directly. Many have flagged illegal or altered re-packaged goods, which rarely hold our performance markers. We regularly brief customer service and distribution teams on the risks and signs of tampering, reducing the risk of poor results or costly recalls downstream.

    Being selective about distribution partners also keeps our product lines clean. Anyone handling our O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)formaldoxime follows the standards we set: no cross-packing, thorough storage records, transparency on final destination, and unbroken chain-of-custody. These measures build long-term trust, especially in a market where end users depend on consistency to protect jobs, yields, or years of research.

    Building for the Future

    Markets evolve, regulations tighten, and new applications emerge. By listening to users, investing in our production equipment, and sticking to a philosophy where no compromise on quality or safety factors stands, we stay ahead of shifts in demand. Our experience with O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)formaldoxime shows that even highly technical, seemingly niche products thrive in partnership: customers bring challenges from the field or lab, we bring manufacturing muscle and a culture dedicated to honest feedback and improvement.

    New applications in pharmaceutical and materials chemistry bring both excitement and responsibility. Handling custom requests for purity, physical profile, or labeling takes close coordination with compliance teams and regular fine-tuning of process windows. We maintain open books when it comes to sharing how we source, process, pack, and ship—recognizing that for users with tight timelines and hard deadlines, transparency is as important as technical specification. Working in this field, real relationships and reputational capital matter as much as cutting-edge gear or big capacity.

    Some products draw a clear line between the people who make them and those who use them. With O-(Methylcarbamoyl)-1-Dimethylcarbamoyl-1-(Methylthio)formaldoxime, our success relies on closing that gap—listening carefully, solving shared problems, and keeping quality non-negotiable. That approach supports everyone from new technical leads to veterans who built their reputation on reliable chemical performance, now and for years to come.