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N-Methyl-N-Butylamine

    • Product Name N-Methyl-N-Butylamine
    • Alias N-Methylbutylamine
    • Einecs 202-752-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    158978

    IUPAC_name N-methylbutan-1-amine
    CAS_number 109-73-9
    Molecular_formula C5H13N
    Molar_mass 87.16 g/mol
    Appearance Colorless liquid
    Boiling_point 89 °C
    Melting_point -86 °C
    Density 0.75 g/cm³
    Solubility_in_water Miscible
    Flash_point 12 °C
    Vapor_pressure 94 mmHg (20 °C)
    Refractive_index 1.401
    Odor Amine-like

    As an accredited N-Methyl-N-Butylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500 mL amber glass bottle with a secure screw cap, labeled "N-Methyl-N-Butylamine," displaying hazard symbols and product details.
    Shipping N-Methyl-N-Butylamine should be shipped in tightly sealed, chemical-resistant containers, clearly labeled, and compliant with local, national, and international regulations. Handle as a flammable liquid; transport in an upright position, away from heat sources, and with proper documentation. Ensure compatibility with transport vehicle and provide access to appropriate spill and emergency response equipment.
    Storage N-Methyl-N-Butylamine should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep it separate from oxidizing agents, acids, and halogens. Proper labeling is essential. Store in accordance with local regulations and ensure appropriate spill containment measures are in place to prevent environmental contamination.
    Application of N-Methyl-N-Butylamine

    Applications of N-Methyl-N-Butylamine in Industrial Manufacturing

    N-Methyl-N-Butylamine serves as a specialized intermediate and processing aid in several industrial manufacturing routes, each with distinct handling norms, dosage ranges, integration processes, and final product requirements. As a direct manufacturer, we provide consistent specification and technical backup for high-value chemical conversion, agrochemical, pharmaceutical, and polymer use.

    1. Agrochemical Active Ingredient Synthesis

    Downstream agrochemical producers use our N-Methyl-N-Butylamine as a selective alkylating agent and amination intermediate in the synthesis of certain herbicide and insecticide actives. It enables the formation of tertiary amine moieties under controlled temperature and pressure, improving yield and purity in actives such as phenoxyalkylamine derivatives. Batch records and traceability are critical due to strict environmental management and worker safety protocols.

    Industry compliance standards

    • REACH Regulation (EC No 1907/2006)
    • US EPA TSCA inventory listing
    • China Ministry of Ecology and Environment (MEE) environmental standards for pesticide intermediates
    • ISO 9001:2015 certified quality management system

    Typical usage ratio

    • 5–12% by mole relative to substituted aniline or phenol starting materials
    • Ratio adjusted based on reactivity of co-reactants and required conversion rates

    Downstream process integration

    • Feeds into amination or alkylation steps following initial aromatic substitution
    • Integrated in semi-batch reactors under nitrogen atmosphere
    • Enters closed piping directly from tank storage to reaction vessels
    • Subject to in-line monitoring for residual amine at each blending point

    Final product types

    • Herbicide actives: e.g., phenoxy herbicides (MCPA, 2,4-D esters), urea derivatives
    • Insecticide intermediates
    • Plant growth regulator actives
    • Custom pesticide formulations for post-patent applications

    2. Pharmaceutical API Intermediate Manufacture

    Pharmaceutical companies rely on N-Methyl-N-Butylamine in the scalable synthesis of tertiary amine-bearing API intermediates. Key examples include functional group installation for antihypertensive and CNS drug candidates. Strict process control is required to comply with cGMP and batch approval. The material must exceed purification thresholds for low-level genotoxic impurity concerns and is tracked from storage to charging with robust batch documentation.

    Industry compliance standards

    • European Pharmacopoeia General Monograph 2034 (Impurities in Drug Substances)
    • US FDA cGMP (21 CFR Parts 210 & 211)
    • Chinese Pharmacopoeia standards for API intermediate quality
    • ICH Q3A/B guidelines for residual solvent and impurity control

    Typical usage ratio

    • 1–3 molar equivalents based on core structure derivatization requirements
    • Charge ratio calculated per step based on intended substitution pattern and reactivity of substrate

    Downstream process integration

    • Transferred by metered addition from validated storage vessels to synthesis reactors
    • Used in late-stage functionalization or quaternization steps of API building blocks
    • Combined with controlled pH regulation for impurity minimization
    • Typically followed by aqueous work-up and organic phase extraction to control residuals

    Final product types

    • Intermediates for antihypertensive agents
    • CNS small molecule API precursors
    • Oncology research compounds for clinical trial material supply
    • Custom pharmaceutical intermediates for contract synthesis

    3. Rubber Processing Chemical Production

    Tire and technical rubber manufacturers utilize N-Methyl-N-Butylamine as a building block in antiozonant and accelerator synthesis. The amine is introduced to build alkylated diphenylamine or sulfenamide accelerators, essential for controlling vulcanization kinetics and improving end-use resistance. Dosing is tightly monitored to prevent off-spec accelerator byproducts, and every batch is validated through in-process QC.

    Industry compliance standards

    • ASTM D4678 Standard Practice for Rubber Chemicals
    • EU Regulation (EC) No 1907/2006 (REACH) for rubber additives
    • China GB/T 19252 for accelerator specifications
    • ISO 14001:2015 for production environmental management

    Typical usage ratio

    • 3–9% by mole in diphenylamine-based antiozonant production
    • Adjusted within this window per specific sulfenamide or dithiocarbamate blend formulation

    Downstream process integration

    • Pumped from bulk storage to closed reaction systems with in-line filtration
    • Amine feeds directly into condensation or coupling stage
    • Undergoes vacuum distillation purification post-reaction
    • Residual amine fraction is recycled, minimizing chemical loss and wastewater

    Final product types

    • Rubber accelerators (e.g., CBS, TBBS, DCBS)
    • Antiozonant blends for tire compounds
    • Industrial hose and belt antidegradant masterbatches
    • Polymer stabilizers for EPM and SBR applications

    4. Organic Corrosion Inhibitor Synthesis

    The oil refining and metal treatment industries apply N-Methyl-N-Butylamine in developing film-forming corrosion inhibitors for pipelines, storage tanks, and acid-cleaning solutions. Its reactivity profile supports imidazoline and quaternary ammonium inhibitor synthesis. Each application requires custom formulation based on target metal, process temperature, and transportation medium. Usage is rigorously limited by environmental and safety standards in most regions.

    Industry compliance standards

    • API RP 932-B for refinery corrosion inhibitors
    • US EPA TSCA listing for oilfield chemicals
    • China GB 24754 on anti-corrosive agent limits in circulating water
    • OSHA Hazard Communication Standard (29 CFR 1910.1200)

    Typical usage ratio

    • 4–8% by weight in reaction compositions for imidazoline-type inhibitors
    • Dosing evaluated per target corrosion rate and service fluid character

    Downstream process integration

    • Fed continuously to pre-neutralized batch reactors
    • Reacted with tall oil acids or polyamines under controlled agitation
    • Residual amine neutralized prior to packaging
    • Active testing for film persistency and water solubility after blending

    Final product types

    • Pipeline corrosion inhibitor concentrates
    • Oilfield acidizing and pickling inhibitor blends
    • Closed-loop cooling system additive packages
    • Finished blends for refinery and storage tank corrosion protection

    5. Textile Fiber Modification Chemical Synthesis

    N-Methyl-N-Butylamine enables synthesis of cationic surfactants and textile treatment chemicals, improving dye affinity and antistatic properties in polyester, nylon, and acrylic fibers. These specialty amines are incorporated into quaternary ammonium finishing agents or as intermediates for high-performance softeners. Integration is batch-based, with strict limits for amine content and residual odor according to global textile and environmental standards.

    Industry compliance standards

    • OEKO-TEX Standard 100
    • ZDHC MRSL – Zero Discharge of Hazardous Chemicals guidance
    • EU REACH SVHC (Substances of Very High Concern) regulations
    • China GB/T 17592-2011 on textile chemical residues

    Typical usage ratio

    • 2–7% by weight on surfactant or finishing formulation basis
    • Ratio set to achieve targeted surface charge and hand feel in finished fibers

    Downstream process integration

    • Added directly to quaternization reaction with fatty acid chlorides
    • Post-reactive distillation ensures removal of excess non-reacted amine
    • Final blends subjected to GC analysis for amine residuals prior to shipment
    • Integrated in the final emulsion blending for industrial-scale textile finishing

    Final product types

    • Cationic textile finishing agents
    • Antistatic treatment additives for synthetic fibers
    • High-performance textile softeners for knit and woven goods
    • Wash-durable surface modification chemicals

    6. Performance Coatings Resin Manufacture

    Paint and specialty coating manufacturers utilize N-Methyl-N-Butylamine for synthesizing certain blocked isocyanate resins and catalytically active additives. Its incorporation moderates curing profiles, improves film toughness, and supports solubilization in waterborne and solventborne systems. Dosage and purification follow strict internal QC protocols to minimize color development and maintain shelf stability throughout distribution.

    Industry compliance standards

    • US EPA VOC Emission Standards for Coatings
    • EU Directive 2004/42/EC relating to paints and varnishes
    • ISO 9001:2015 quality management for batch traceability
    • China HJ 2537 for waterborne coatings production

    Typical usage ratio

    • 1.5–4.0% by weight in polyurethane or acrylic resin formulations
    • Level regulated based on required cure speed and crosslinking density

    Downstream process integration

    • Charged to pre-mixing vessels for in-situ blocking of aromatic isocyanates
    • Fed into resin kettle under temperature-controlled conditions
    • Final purification includes distillation to remove free amine before blending into master batch
    • Sampled post-synthesis for color, viscosity, and residual analysis

    Final product types

    • Blocked isocyanate prepolymers for 2K polyurethane coatings
    • Waterborne resin dispersions requiring low VOC content
    • Automotive OEM and refinishing coatings
    • High-performance industrial protective topcoats
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    Certification & Compliance
    More Introduction

    N-Methyl-N-Butylamine: Crafted by Hands That Know Amines

    The Story of Real Chemistry

    In our lab, chemical innovation always starts with knowing where each raw material comes from and why we shape it the way we do. N-Methyl-N-Butylamine stands as a result of years spent refining amine processes, solving heat control problems, and balancing reactivity so that our customers—whether in pharma, agrochemicals, or specialty manufacturing—don’t face surprises. This is not a generic blend sourced from unknown brokers or packed and shipped from another continent. It’s made here, by our people, using technology we developed through trial, error, and getting up early to troubleshoot each step.

    What sets N-Methyl-N-Butylamine apart isn’t just its clear, colorless liquid form or the measured purity that shows up on every batch certificate. The process behind it matters—real temperature control, genuine reactor cleaning, and solid batch tracking that doesn’t cut corners. Over time, we discovered that customer complaints almost always traced back to shortcuts: using recycled stock, hasty filtration, or ignoring water content in the final distillate. This product is the opposite. Every lot gets verified. Moisture levels stay tight, because too much water disrupts reactions in pharma and destabilizes agrochemical intermediates. Consistency, batch to batch, matters more than flashy packaging or high-pitched sales claims.

    Model and Specifications That Serve Real-World Uses

    We produce N-Methyl-N-Butylamine to a specification that typically supports 99% minimum purity, often exceeding that mark by a fraction or two. The amine’s structure—C5H13N—gives it a distinct reactivity compared to bulkier or more linear amines. This molecule handles alkylation, reductive amination, and cyclization steps smoothly in lab and plant settings. We keep residual solvents and heavy metals strictly below the detection limits common in regulated industries, supporting applications where clean downstream chemistry is not a negotiation.

    No two customers run the same reaction, and there’s no off-the-shelf solution that suits everyone. Pharma synthesizers want near-zero water and stable boiling. Agro producers care about consistent delivery in drums, ready to feed inline blending, and purity that prevents unexpected field residues. In both cases, what’s delivered has already made it through our GC and Karl Fischer stations, not as a rubber stamp, but because we know small variations create big headaches.

    Usage: What N-Methyl-N-Butylamine Actually Achieves

    Chemists don’t ask for N-Methyl-N-Butylamine unless the application demands it. In pharmaceuticals, it acts as a building block for numerous APIs, standing up to reductive amination and acylation steps where other amines—diethylamine, triethylamine, mono-n-propylamine—tend to fall short. The methyl and butyl groups balance steric hindrance, allowing for smooth nitrogen insertion without the byproduct tangle seen with bulkier or more branched analogs. That streamlines purification and saves time on column work, which is every process team’s goal.

    Crop science and agrochemical teams value this molecule as a clean intermediate. We’ve seen our product go into the next generation of fungicides, growth regulators, and seed treatment chemicals. The low impurity profile means less downstream cleaning, which keeps environmental controls satisfied and reduces remediation costs at the customer’s plant. The liquid form pours cleanly and doesn’t clump, so dosing automation keeps running—a simple detail until a clogged valve halts a hundred-liter production run.

    Every year, we field customer questions about custom blends or modified grades. Sometimes the requested tweak is tighter purity, other times it’s adjustments in stabilizer content to fit high-heat processes. We oblige wherever possible, because the way people use N-Methyl-N-Butylamine is never static. Project timelines shift, solvent recoveries tighten as plants go greener, and trace-level impurity requirements sharpen. Any amine made as a one-size-fits-all loses relevance fast. Instead, we stake our name on making sure the chemistry behind our product evolves—or there’s no reason for us to compete.

    Standing Apart from Common Amines

    It’s tempting to think all alkyl amines fill the same gap. Our experience says otherwise. Take N-Methyl-N-Butylamine versus traditional secondary amines like diethylamine or morpholine. Diethylamine brings volatility and a sharp, ammoniacal odor, which wreaks havoc on closed environments. Morpholine, though useful, doesn’t carry the same balance of hydrophobicity and reactivity for precise N-alkylation. On the shop floor, process engineers notice that N-Methyl-N-Butylamine plays better with sensitive catalysts in pharmaceutical scale-up. Reaction profiles prove sharper, yields sit consistently higher, and the impurity fingerprint narrows, improving chances of regulatory approval or batch sign-off.

    We pay close attention to amine sourcing because even minor shifts in plant origin or storage method wrecks product quality. Recycled amine held in steel drums too long picks up iron, shifting color and throwing off reactions. Off-grade shipments with higher boiling impurities look fine on a quick GC run but lead to downtime. Our commitment stays anchored in full vertical tracing: from supplier approval through shipment, our team manages every handoff under strict SOPs built from three decades of experience.

    What Matters in Large-Scale Manufacturing

    Big reactors and small flasks both reveal shortcuts quickly. In early years, our batches saw occasional side reactions that produced off-odor fractions. We learned to refine distillation sequences, investing in real-time monitoring and trained operators who know a funny smell before an off-spec batch reaches customers. On top of that, packing and storage stay under controlled nitrogen blanketing, extending shelf life and preserving the amine’s original characteristics over longer storage.

    Run-to-run consistency saves headaches. If a customer’s test reaction varies in yield by five percent between drum deliveries, suspicion falls on us first, and rightfully so. That’s why we run reference analytics on split lots and store retention samples from every drum. These aren’t bureaucratic steps—they’re practical habits. After all, we’re the ones taking the call when downtime costs thousands per hour.

    Transport logistics matter as much as synthesis. We learned hard lessons shipping in poorly lined containers, where traces of corrosion or moisture in packaging lead to compensation claims. Stainless steel drums and lined IBCs keep the amine as it left our facility. Temperature during transport is tracked and flagged, since amines don’t forgive heat spikes. Every replacement is an added cost, and trust—once gone—takes years to repair.

    Target Industries and Application Insights

    N-Methyl-N-Butylamine fits best where process chemists demand reliable supply and partners who understand nuance. In API synthesis, it unlocks certain N-alkylamine frameworks with far less scrambling than what we’ve seen with N-methylethylamine or bigger branched options. That edge pulls through the whole supply chain, reducing cleanup burdens after work-up and avoiding smell complaints from pilot plant operators.

    The product never stops being useful to agrochemical formulators, who want unreactive, low-residue amines for intermediates going straight to formulation. Residual metals, water, and non-amine volatiles get scrutinized since every small deviation creates requalification work at their end. This expectation pushes us to clean up processes beyond the minimum shown on a spec sheet. It’s not a marketing slogan—it’s a daily reality because we know what happens when someone else’s process halts because of a detail missed on our side.

    Another segment using N-Methyl-N-Butylamine comes from specialty materials. Its use as a starting point in polymer modification or for custom surfactants keeps growing. In these spaces, performance is everything—consistency, low odor, and strong batch documentation travel further than unreliable cost savings.

    Addressing the Real-World Challenges

    Customers sometimes worry that global uncertainties could disrupt amine supplies or skew pricing. In our history, supply volatility crept in mostly through reliance on brokers or offshore packers. So, we built redundancy into our sourcing networks and developed internal reserves. We never mix leftover product from multiple origins to fill a drum—traceability remains intact, every batch leading back to a specific reactor run. That means fewer surprises if an issue surfaces six months after delivery. Customers value traceability not as a nice-to-have, but as protection against regulatory pressure or recall costs.

    Counterfeit and off-spec product continues to surface in the amine trade, especially when buyers chase only on price. Don’t trust an amine unless you can ask for—and get—full documentation, true certificates, and clear batch origins. We support every shipment with actual test data—not a generic analysis, but a report pulled from the same drums that get loaded onto trucks. Sometimes this slows down shipment a day or two, but the calls we no longer take about out-of-spec product easily pay for the delay.

    Shipping, too, harbors potential headaches. Whether shipping by the barrel or by the tank, the cleanliness and certification of the transport vehicle carries real risk. We once traced a contamination issue to a third-party logistics partner who had cut corners in tank cleaning—nobody caught the issue until field samples hit the customer's QC lab, several thousand kilometers away. Since then, our standard demands full cleaning verification, with our own team double-checking the process. These steps seem picky, but they’re grounded in the reality of what happens when QA failures cost production slots and waste customer time.

    Customers sometimes require regulatory support—be it for REACH registration, TSCA compliance, or local workplace data. Our compliance team engages not as an afterthought, but as part of the ongoing conversation between plant, paperwork, and product. We’ve found that clear channels between production, document management, and client-side regulatory teams eliminate confusion and speed up approvals, especially for new applications or novel downstream formulations.

    Continuous Process Improvement and Customer Feedback

    The best ideas for tightening quality controls have come from situations where customer feedback revealed a gap in our procedures. Feedback isn’t framed as a complaint—it’s hard-earned data. More than once, a customer running a sensitive synthesis reported faint coloration. That highlighted a trace impurity that our own analytics missed until we upgraded both methodology and training. Over time, this approach—listening closely, iterating quickly—drives our processes forward.

    As green chemistry grows in importance, we work toward lower-waste production streams, improved solvent recovery, and energy-efficient distillations. These advances create costs early, but over the product’s lifecycle, they lower emissions profiles and enhance compliance standing for customers. Industrial partners care deeply about these gains, as do teams running pharmaceutical validations with an eye on future environmental audits. N-Methyl-N-Butylamine plays a small but important part in those storylines—it’s part of how refined chemicals move toward a lower footprint while supporting high-value synthesis.

    Trust Built Across the Supply Chain

    Long relationships in the chemical business depend on more than once-a-year contract negotiations. We grew our N-Methyl-N-Butylamine business alongside customers who flagged issues early: cloudiness in storage, valve residues, or odd GC peaks under certain conditions. By working directly with formulators, process engineers, and QC teams, we shortened troubleshooting and launched incremental fixes that benefit every customer, not just a single order.

    Strong QC doesn’t stop once the product leaves our gates. We encourage customer audits, provide sampling from retained drums, and routinely supply full analytical run-throughs on request. Confidence grows from transparency and handles mistakes with accountability, not spin. That’s why customers who move onto new roles in other companies often stick with our N-Methyl-N-Butylamine even when purchasing teams push for cheaper suppliers—knowing the difference isn’t academic, it’s measured in longer uptimes and fewer lost batches.

    Looking Forward: Where Precision Meets Responsibility

    We recognize N-Methyl-N-Butylamine as more than a commodity—it’s a foundation for complicated syntheses and a trusted endpoint for many researchers. Every improvement in yield, consistency, or environmental profile ripples up the supply chain, saving hidden costs and enabling new applications. The value of close collaboration, tight process control, and shared transparency with customers anchors our philosophy.

    In a market flooded by lookalikes and shortcut products, we differentiate by ownership of the entire process. That means the chemist signing off on the batch, the operator overseeing filtration, and the compliance lead preparing documentation all answer to the customer’s needs. We’ll keep evolving N-Methyl-N-Butylamine according to the changes in the industries we supply, knowing that what’s measured, shared, and improved directly benefits people down the line—from the pilot plant, through formulation, and into the hands of the end user.

    Each time someone reaches for our product, we consider it a handshake built on years of technical knowledge and stubborn persistence. N-Methyl-N-Butylamine may never make headlines, but it will keep helping chemists, engineers, and manufacturers push boundaries, lower risks, and trust every barrel—because that’s the standard we hold, batch after batch.