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N-Hexylamine

    • Product Name N-Hexylamine
    • Alias hexan-1-amine
    • Einecs 203-684-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    503573

    Chemical Name N-Hexylamine
    Cas Number 111-26-2
    Molecular Formula C6H15N
    Molecular Weight 101.19 g/mol
    Appearance Colorless to yellowish liquid
    Odor Amine-like
    Boiling Point 131-133 °C
    Melting Point -70 °C
    Density 0.767 g/mL at 25 °C
    Solubility In Water Slightly soluble
    Flash Point 32 °C (closed cup)
    Refractive Index 1.417 at 20 °C
    Vapor Pressure 15 mmHg at 25 °C
    Pka 10.56 (for conjugate acid)
    Un Number 2733

    As an accredited N-Hexylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing N-Hexylamine is packaged in a 500 mL amber glass bottle with a tight-sealing cap, labeled with hazard and safety information.
    Shipping N-Hexylamine should be shipped in tightly sealed containers, protected from physical damage, heat, and sources of ignition. Store in a cool, well-ventilated area, and ensure proper labeling according to hazardous material regulations. Handle as a flammable, corrosive substance with appropriate hazard communication and personal protective equipment. Comply with all transportation regulations.
    Storage N-Hexylamine should be stored in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and incompatible substances such as acids and oxidizers. Keep the container tightly closed and properly labeled. Store in a secure, chemical-resistant area away from direct sunlight and moisture. Use corrosion-resistant containers, and ensure access to spill control materials and appropriate safety equipment.
    Application of N-Hexylamine

    Applications of N-Hexylamine in Industrial Manufacturing

    As a direct manufacturer of N-Hexylamine, we supply global industrial partners in niche fields where this chemical plays a functional and process-critical role. Below are several major application scenarios, each reflecting real-world downstream industries, practical formulations, compliance standards, and end-use products.

    1. Production of Corrosion Inhibitors for Industrial Cooling Water

    N-Hexylamine serves as an essential intermediate in synthesizing alkylated amine-based corrosion inhibitors designed for closed and open-recirculating water systems. By reacting in formulated blends with carboxylic acids or with fatty acids, it improves long-term steel and copper protection in heat exchangers and pipelines. Users adjust concentration based on water parameters such as hardness, pH, and corrosive ions, and every production batch must meet regional environmental and health & safety standards.

    Industry compliance standards

    • ASTM D1384 (Corrosion Test of Engine Coolants)
    • EN 12160 (Corrosion inhibitors for water systems)
    • REACH (EC No 1907/2006, annexes for water treatment chemicals)
    • Environmental Protection Agency (EPA) guidelines for effluent discharge

    Typical usage ratio

    • Ranges from 2% to 10% by weight in finished inhibitor concentrates; formulators adjust based on water chemistry and corrosion inhibitor type (e.g., filming amines, neutralizing amines)

    Downstream process integration

    • Charges into reaction vessel during alkylamine-amidation or quaternization steps, followed by blending with chelating agents and antifoams before drum or tote filling

    Final product types

    • Liquid corrosion inhibitor blends for industrial cooling towers
    • Chemical dosing packages used in power plant water circuits
    • Closed-loop HVAC corrosion control products

    2. API Intermediate for Pharmaceutical Manufacturing

    Active pharmaceutical ingredient (API) manufacturers use N-Hexylamine as a key alkylating moiety in the synthesis of antihypertensive and psychoactive drug intermediates. Its controlled use and quality parameters fall under strict pharmacopoeial specifications, and the volume used per synthesis batch depends on the target molecule yield and process efficiency.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • USP-NF and EP monograph standards for intermediate quality
    • US FDA 21 CFR Part 210/211 (cGMP for Drugs)
    • Local Ministry of Health drug manufacturing licenses

    Typical usage ratio

    • Usually 1.2–1.5 molar equivalents per target intermediate per reaction batch, with adjustments based on stoichiometry and reaction conversion rates

    Downstream process integration

    • Added during alkylation or amination steps in the synthesis of API intermediates (e.g., during reductive amination of ketone substrates or alkyl halide substitution reactions)

    Final product types

    • API intermediates for antihypertensive drug synthesis (e.g., hexylamine derivatives)
    • Precursors for psychoactive and anti-inflammatory pharmaceuticals

    3. Agrochemical Synthesis: Herbicide and Pesticide Formulations

    N-Hexylamine finds application in the production of selective herbicides and growth regulators through the formation of amine salts or quaternary ammonium compounds. Manufacturers must maintain compliance with national chemical safety and residue regulations throughout the formulation process, and the dosing ratio is optimized according to the active ingredients and crop specificity.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 11083 (Herbicides—Test methods for determination in formulations)
    • EPA FIFRA (Federal Insecticide, Fungicide, and Rodenticide Act)
    • REACH chemical safety reports for herbicide intermediates

    Typical usage ratio

    • Employed at 3%–8% by weight in concentrated technical-grade herbicide synthesis—actual percentage depends on the type of salt or adjuvant required in the final emulsifiable concentrate or water-soluble formulation

    Downstream process integration

    • Introduced at the neutralization or quaternization stage when converting acid herbicide actives into water-soluble amine salt forms; followed by concentration, stabilization, and packaging lines

    Final product types

    • Formulated amine salt herbicides for field application
    • Pesticide adjuvants compatible with tank-mix applications

    4. Rubber Chemical Accelerators and Vulcanization Agents

    Synthetic rubber manufacturers use N-Hexylamine in producing arylamine and sulfonamide accelerators, which optimize vulcanization reactions for tires, seals, and technical rubber goods. Compliance with international automotive and rubber standards is essential, and the quantity incorporated is tuned for each specific rubber compound grade and customer requirement.

    Industry compliance standards

    • ISO 9001:2015 (Quality management systems for rubber chemicals)
    • ASTM D4671 (Rubber chemicals—Accelerator and antioxidant purity requirements)
    • Automotive OEM technical specifications for tire and seal production
    • REACH substance registrations for rubber additives

    Typical usage ratio

    • Used at 0.5%–2% by total compound weight; variations reflect rubber grade, accelerator synergy, and final curing profile

    Downstream process integration

    • Reacts with sulfenyl chlorides or aniline derivatives in chemical synthesis blocks; blends are then incorporated during the compounding step prior to internal mixing and final extrusion or calendering

    Final product types

    • Accelerator masterbatches for tire tread and sidewall compounds
    • Vulcanization additives for engineered rubber parts and sealing profiles

    5. Dye and Pigment Intermediate for Industrial Colorants

    Colorant and pigment manufacturers rely on N-Hexylamine as a building block in the synthesis of certain azo and phthalocyanine dyes, used primarily for coloring plastics, fibers, and paints. Attention to purity and batch traceability is mandatory in supply to pigment houses due to downstream product stability and color consistency requirements, and the input ratio is set per target chromophore structure.

    Industry compliance standards

    • ISO 9001 (Quality systems for colorant production)
    • EN 71-3 (Toy safety: migration of certain elements in dyed materials)
    • REACH Annex XVII (Restriction of hazardous substances in coloring agents)
    • GMP for coloration in food-contact and toy applications, where required

    Typical usage ratio

    • 1–5% of total dye/pigment synthesis batch, altered according to molecular design and interaction with diazotized intermediates during coupling reactions

    Downstream process integration

    • Enters into the colorant synthesis reactor during primary condensation or amination, often in solvent suspension; proceeds through filtration, washing, and drying before blending or micronization

    Final product types

    • Polymer colorant masterbatches and dispersions for plastics extrusion
    • Textile dyes and coloring pastes for fiber and yarn processing
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    Certification & Compliance
    More Introduction

    N-Hexylamine: Quality, Consistency, and Real-World Use

    Understanding N-Hexylamine in the Lab, on the Line, and in the Field

    N-Hexylamine is more than just a chemical compound on a spec sheet—it is a material our team produces through years of careful process development, tested daily in real manufacturing conditions. The chemical's structure is simple—an amine with a straight six-carbon chain—but its applications and character are far from elementary. In our own synthesis operation, we take pride in running every batch through detailed monitoring, from reagent choice to finished drum. This effort provides a reliable supply of high-purity N-Hexylamine, with clear, nearly colorless liquid form, a mild amine odor, and a boiling point comfortably above room temperature for most plant line conditions.

    There is no substitute for direct production experience when we measure purity, manage storage, or transfer amines like this one. Our model line for N-Hexylamine demonstrates how essential it becomes to keep water content at a minimum—a few hundred ppm of moisture can cause haze, trigger side reactions, and even change the response in sensitive electronic surfactant synthesis. We target typical purity above 99.5%, always verified by gas chromatography, as lesser grades invite inconsistent reactions and wasted time. Genuine N-Hexylamine, as we make it, pours clear into the receiving vessel and stays stable across a season's work.

    Specification Is More Than a List

    Industry standards speak to a minimum assay and physical characteristics. Yet, based on our own routine in the plant and in the field, we recognize what matters in each container is more than just numbers. For N-Hexylamine, the absence of short-chain or branched amine impurities is crucial. For specialty synthesis or small-molecule pharmaceuticals, even trace oddball analogs can throw a catalyst off or leave an unwelcome odor in the final product. Every batch we send leaves this plant after receiving both analytical attention and an operator’s direct verification. After years producing and handling this compound, we have learned that paper purity does not always match practical reactivity—so we commit to verifying both with regular process performance checks.

    Moisture management may look like a paperwork box to check, but in alkyl amines, a real-world difference exists between ‘spec-compliant’ and ‘runs reliably in your reactor.’ Our technical team has lost count of the midnight calls from downstream formulators who have encountered amines with fine print exceptions on the water or volatile base content. We have revised exit protocols to ensure that solubility and reactivity stay tight batch to batch, even if it means running an extra vacuum step or holding a truck until results return clear. That difference is not visible on a certificate, but it is clear to anyone who has managed a polymerization feed that goes cloudy for no apparent reason.

    N-Hexylamine in Everyday Use

    People often think of N-Hexylamine as a specialty item, reserved for select syntheses or as a rare additive. Our experience shows a different story. This molecule stands at the crossroads of several sectors—fine chemicals, crop protection actives, surfactants, corrosion inhibitors, fuel additives, and even textile auxiliaries. That indirect presence in daily-use products keeps demand steady and challenging. In our operation, the system needs to flex from kilo-lab runs for new pharmaceutical intermediates to drum-lot production serving a fuel blending plant. The versatility of N-Hexylamine comes from its balanced chain length—not so short as to volatilize away, not so long as to gum up the pump or slow a liquefaction.

    Surfactant formulators regard this chemical as a choice for specific cationic applications. Unlike shorter amines, such as N-propyl- or N-butylamine, N-Hexylamine maintains both solubility and a manageable vapor pressure. That makes it friendlier for open-tank processes and reduces evaporation loss. Our team has witnessed the way this stability impacts blending: less odor, less material loss, tighter control on your batch sheets, and fewer headaches downstream. Its chemical structure brings just the right combination of primary amine reactivity and hydrocarbon character for selective alkylation or reaction with acid chlorides.

    Direct Production—The Only Reliable Route

    Producing N-Hexylamine on our site means we control every upstream input, monitor each processing step, and respond quickly if small changes in raw material lots occur. Over the years, we have learned to expect variability and build tolerance into the manufacturing line. Batch logs tell the story: small shifts in temperature or feed rate can lead to a subtle increase in byproducts, such as secondary amine or isomeric impurities. We refine our catalyst and purification conditions for every campaign, adjusting distillation and drying times as needed. Our on-site production crews stay trained on handling and sampling, knowing that operator vigilance remains the best alarm system for any out-of-trend result.

    Many new customers ask us whether residual solvents or metals pose a risk. By managing synthesis in-house, instead of sourcing sporadic imported lots, we certify absence of unwanted residues, guided by regular third-party testing and internal benchmark studies. For specialty uses like active pharmaceutical intermediates, this control becomes non-negotiable—a single contaminated drum can result in cascading losses and schedule overruns for our partners, and those headaches often come back to the manufacturer with a request for root cause analysis.

    Comparisons: What Sets Real N-Hexylamine Apart

    We field constant questions about the differences between our N-Hexylamine and what traders push in the market. Many supplies land from regional wholesale lots, repackaged or transshipped without genuine technical traceability. Over the years, we have run comparative GC-MS and NMR on dozens of these off-spec samples. Patterns emerge: more variable water content, retention of lighter and heavier alkyl amines, and a distinct rise in amine odor that betrays poor distillation or old storage conditions. Our direct manufacture sidesteps these pitfalls. Service teams maintain the tank farm and terminal lines, flushing and testing regularly, always working to keep the product free of air exposure and cross-contamination.

    Some customers get tempted by lower price points on imported or blended amines but end up paying for it in higher downstream losses. For example, in agricultural intermediate manufacture, our support staff have dealt with ‘mystery residue’ issues in neutralization runs using bargain alternatives. Cost control programs benefit more from reliable run-time data and less from questionable short-term savings. We always counsel potential clients with one rule: total cost includes the hidden price of downtime and the cost of batch remediation. If every second run triggers washouts or filter changes, that number always dwarfs the incremental chemical savings.

    Application Details from the Plant Floor

    Every week, our technical engineering group takes calls from customers looking for new approaches in their plants. The lesson they carry is that there are no shortcuts in handling amines. For fuel additive clients, we have configured closed transfer lines and nitrogen blanketing systems, which our own team uses to minimize oxidation and vapor loss on transfer. For researchers trialing new corrosion inhibitors, we provide pre-tested material in returnable totes, sharing our cylinder handling SOPs so the end-user receives the same quality we work with ourselves.

    Pharmaceutical developers often need very high-purity, low-residue N-Hexylamine. Meeting those specs requires us to re-tool our QA checks, adding fresh panel tests and running extra micro-trace analytics, sometimes on twenty-year-old UPLC equipment alongside the latest detectors. Our lab crew sees the difference first-hand, sometimes catching trace halides or residual transition metals long after a drum meets ordinary industry standards. For critical applications, that commitment can mean the difference between a successful regulatory filing and weeks spent reprocessing. It is not enough to meet specification—it requires constant validation and a willingness to dig into batch history when something does not look right.

    Storage, Handling, and Operator Knowledge

    N-Hexylamine needs careful handling—our team’s collective habit is to keep it under nitrogen, far from heat and open air, and always in clean, dry tanks. The compound's vapor can be strong, and direct plant experience shows that even routine transfers call for splash protection, fume extraction, and quick access to neutralizing agents for any accidental splashes. We share our learning here with every new client, laying out detailed guidelines based on site practice, not just what the MSDS says. Local conditions influence everything: humidity, temperature, tank coatings, and even transfer valve design can change product stability.

    In places with high relative humidity, our site operating procedures dictate that storage vessels stay sealed with positive pressure nitrogen. That step does not just look good on audit day—it keeps the amine bright and clear, with no off-odors or cloudiness over months in storage. We routinely audit our own storage performance, correlating product quality with actual storage durations and exposure events. By reviewing real-world handling data, we help customers adapt our field methods to their own plants.

    Safety and Environmental Practice

    Our production shop emphasizes that safe operation stems from habits, not from rules alone. N-Hexylamine needs respect: it easily absorbs through skin, and its vapors can irritate eyes and airways. We train every new operator on protective gear, ventilation, and spill cleanup—then track incident logs to drive process improvements, visiting storage areas and mixing rooms regularly. Incidents tend to arise from shortcuts: unsealed drums, accidental mixing with incompatible chemicals, or neglecting splash control on pumps.

    In our waste treatment area, process water and spent cleaning fluids pass through pH neutralization and carbon filtration, followed by regular monitoring. With amines, we learned early that local wastewater standards tend to be strict for nitrogenous compounds, especially for sites near surface water. Labs run regular discharge analysis, so that tiny traces cannot accumulate or cause odor or toxicity issues. Environmental practice is not a box to tick for us—local community trust depends on it; so does workforce health.

    Working with End-Users: Real Feedback, Real Improvement

    Customer feedback does not just guide quality—it shapes production schedules, stocking plans, and technical support. Over years of direct work with formulators, production managers, and R&D chemists, we have adjusted grades, prompted investment in new reactors, and introduced batchwise traceability. Some of the most valuable improvements we have made to our N-Hexylamine process came from plant-floor reports: an unexpected residue found after a long-term blend trial, a recurring foam issue traced to microscopic impurity, or a sudden bottle-neck in bulk unloading solved after a site visit. Direct dialogue beats trading specification sheets every time.

    We recognize, too, that communication avoids the worst kind of supply problems. By providing not only our test results but also actual shipment and storage histories, we invite customers—both large and boutique operators—to challenge and refine our process. Many tweaks in our plant, such as inline sample points, shortened transfer hoses, and improved drum lining, are the result of someone else’s perspective. That back-and-forth, between manufacturing floor and field use, makes quality robust in a way no written spec alone supports.

    Innovation and Ongoing Improvement

    Processes and market needs never stand still. As new industries adopt N-Hexylamine, whether in energy storage, specialty silane coupling, or emerging synthetic pathways, we keep revisiting both technical setup and field support. The last decade saw us replace glass-lined reactors with high-efficiency, corrosion-resistant alloys, a change prompted not just by capacity expansion but also by records showing reduced trace metal introduction into final product. We do not consider upgrades a luxury—they are a necessity for reliability.

    Purification systems evolve as well. New selective adsorbents, smart sensors mounted on distillation towers, and finer control of reflux allow tighter cuts, less off-spec side product, and higher recovery. Our technical team stays in active dialogue with instrument vendors to cut analytical lead times and keep delivery schedules predictable. With N-Hexylamine, the lesson is always that reliability builds from the ground up—meticulous process design, patient operator training, and a relentless focus on results.

    Choosing the Right Product: More Than a Name or a Number

    Users often ask about the ‘best’ amine for a job. Pattern recognition, accumulated over years of manufacturing and troubleshooting, leads us to a simple answer: avoid uncertainty. Choose a line where the processes are transparent and repeatable, the test data match the field experience, and the team stands behind each drum that leaves the gate. In our shop, N-Hexylamine is more than a sales item; it is a constantly improved, directly managed material, responsive to every feedback loop available from the marketplace, the lab, and the plant floor.

    As more applications demand reliability and traceability, direct-from-manufacturer sourcing proves to be less a luxury and more an operational necessity. For companies navigating tough regulatory climates, complex product portfolios, and increasingly lean operating teams, every link in the chain counts. Our experience, grounded in day-to-day interaction with this compound, supports the idea that direct, transparent supply keeps real production on track, and keeps trust between provider and user strong.

    Summary: N-Hexylamine from a Producer's View

    Every batch of N-Hexylamine we provide reflects more than technical standards—it embodies a working partnership with our customers. Our approach, built on practical manufacturing discipline, ongoing process upgrades, and a willingness to engage directly with real-world users, means a better outcome for everyone involved. In this compound, as in all chemical manufacture, depth of field experience turns specification into predictable, repeatable results. That remains the truest measure of value—one built up drum by drum, shift by shift, over years of problem-solving production work.