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n-Hexane

    • Product Name n-Hexane
    • Alias Hexane
    • Einecs 203-777-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    964281

    Name n-Hexane
    Chemicalformula C6H14
    Molecularweight 86.18 g/mol
    Casnumber 110-54-3
    Appearance Colorless liquid
    Odor Gasoline-like odor
    Boilingpoint 68.7°C
    Meltingpoint -95°C
    Density 0.660 g/cm³ (at 20°C)
    Solubilityinwater 0.0095 g/100 mL (20°C)
    Flashpoint -22°C
    Vaporpressure 160 mmHg (20°C)

    As an accredited n-Hexane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing n-Hexane is packaged in a 2.5-liter amber glass bottle with a secure screw cap, labeled with hazard and safety information.
    Shipping n-Hexane is shipped in tightly sealed drums, tanks, or bulk containers made of steel to prevent leaks and evaporation. It must be stored in cool, well-ventilated areas, away from sources of ignition. As a flammable liquid (UN 1208), shipping must comply with all regulations concerning hazardous materials transport.
    Storage n-Hexane should be stored in tightly closed containers in a cool, dry, well-ventilated area, away from heat, sparks, flame, and direct sunlight. It should be kept separate from oxidizing agents and acids. Use only explosion-proof electrical equipment and non-sparking tools. Ensure containers are clearly labeled and grounded to prevent static discharge. Avoid storing near sources of ignition.
    Application of n-Hexane

    Applications of n-Hexane in Industrial Manufacturing

    n-Hexane serves as a critical raw material across several industrial sectors due to its high volatility, low odor, and solvent power. Below, we detail specific downstream applications, each with unique industry compliance, process usage, integration steps, and typical final products. All information reflects practical scenarios and regulatory requirements observed in active manufacturing environments worldwide.

    1. Edible Oil Extraction and Refining

    Oil processors rely on n-Hexane for efficient extraction of edible oils from seeds and grains, such as soybean, canola, and cottonseed. The material acts as a hydrocarbon solvent, selectively dissolving triglycerides from plant matrices before the mixture undergoes separation and refining. Process operators must maintain strict adherence to food-grade purity limits and recovery protocols to ensure regulatory approval for consumption and export. Quality control involves continuous monitoring for solvent residue and recovery rates during deodorization and neutralization stages.

    Industry compliance standards

    • Codex Alimentarius Food Additive Standards
    • US FDA 21 CFR 173.270 (Solvent extraction process regulations)
    • EU Regulation (EC) No 1881/2006 (Maximum residue levels in foods)
    • Chinese GB 2760-2014 National Food Safety Standard for food additive use

    Typical usage ratio

    • Oilseed hexane:oil ratios range from 1:1 to 3:1 by mass, depending on seed type and extractor design; modified based on fat/oil yield targets and solvent recycling capability

    Downstream process integration

    • Solvent enters the extractor after seed preconditioning and flaking
    • Mixture passes through desolventizer-toaster and vacuum stripper units
    • Final steps recover n-Hexane for reuse prior to oil refining and deodorization

    Final product types

    • Refined edible vegetable oils (soybean oil, sunflower oil, canola oil)
    • Hexane-extracted soybean meal and other protein meals for animal feed
    • Crude oil for further fractionation or hydrogenation

    2. Polymer and Polyolefin Manufacturing

    In polymerization plants, n-Hexane functions as a major low-boiling diluent and reaction medium, especially in the production of polyethylene (PE) and polypropylene (PP) via solution polymerization processes. Feedstock specifications require precise control of impurity profiles and low aromatic content to prevent catalyst fouling and molecular weight inconsistencies. Onsite QC labs routinely monitor solvent recovery, recycling purity, and hydrocarbon chain distribution to limit downstream variability during pelletizing or film-forming stages.

    Industry compliance standards

    • ISO 4427 and ISO 1872 (Plastics — Polyethylene and Polypropylene specifications)
    • REACH Annex XVII (Polyolefin chemical safety requirements in the EU)
    • CFR Title 21 §§177.1520, 178.2010 (US FDA indirect food contact for plastics)
    • EN 10204:2004 (Material certification for petrochemical feedstocks)

    Typical usage ratio

    • Polymerization reactors operate at 5%–30% n-Hexane by weight in solution, tuned for targeted molecular weight, catalyst activation rate, and viscosity. Ratios are adjusted to key process parameters, reactor type, and resin grade.

    Downstream process integration

    • Solvent blends with monomer and catalyst after feedstock purification and degassing
    • Acts as chain carrier and polymer solubilizer during live polymerization
    • Post-polymerization, operators recover and purify n-Hexane for recirculation

    Final product types

    • Low density polyethylene (LDPE), linear low density polyethylene (LLDPE), high density polyethylene (HDPE)
    • Random and block copolymers of polypropylene
    • Masterbatches, films, and resin pellets for further extrusion/conversion

    3. Rubber and Tire Manufacturing

    Major tire and technical rubber producers incorporate n-Hexane as a solvent for adhesives, cementing, and compounding stages. It serves to dissolve natural rubber, synthetic elastomers, and resins before application to textile cords, bead wires, or tread surfaces. Strict air and occupational safety practices are followed for volatile organic compound (VOC) containment. Facilities run continuous leak detection, recovery, and solvent vapor exhaust systems as required by sector EHS plans.

    Industry compliance standards

    • EPA 40 CFR Part 63 Subpart XXXX (Rubber tire manufacturing NESHAP)
    • OSHA 29 CFR 1910.106 (Flammable liquids handling)
    • EN 13934 (Industrial adhesives and VOC emissions)
    • CEN TR 16663:2014 (Processing of solvents in rubber industry)

    Typical usage ratio

    • 15%–45% solvent content in adhesive compositions, varying with viscosity targets and rubber solubility; blend ratio selected per specific rubber grade and cord type

    Downstream process integration

    • Introduced during rubber mastication or in resin-admixture preparation tanks
    • Applied in dipping, coating, or spraying lines ahead of vulcanization
    • Solvent recovered via drying ovens and scrubber systems for internal reuse

    Final product types

    • Bias and radial tires for automotive, aviation, and OTR segments
    • Technical rubber sheets and industrial hoses
    • Rubberized fabrics and tire cords

    4. Pharmaceutical Intermediate Production

    Pharmaceutical manufacturers employ n-Hexane in select synthesis and purification steps for active intermediates and excipients. Only high-purity, low-residual aromatic grades can be used under GMP and pharmacopeial standards. Common operations include crystallization, phase separation, and solvent extraction, where n-Hexane helps isolate target compounds from complex reaction mixtures. Process validation includes exhaustive documentation of trace solvent residues and solvent recovery efficiency, as required for finished drug approval.

    Industry compliance standards

    • ICH Q3C (Residual Solvents Guidelines)
    • USP <467> (Organic Volatile Impurities)
    • EU GMP Guide Part II (APIs production)
    • Chinese Pharmacopoeia (ChP) monographs for material purity

    Typical usage ratio

    • Solvent volumes typically 2–6X the expected yield mass for crystallization steps; adjusted by compound solubility, batch size, and purity grade

    Downstream process integration

    • Added to post-synthesis reaction mixtures for partitioning and target compound extraction
    • Utilized in final purification, followed by solvent evaporation and recovery
    • Captured solvent recycled after QC clearance for potential reuse within GMP restrictions

    Final product types

    • Active pharmaceutical ingredient (API) intermediates
    • Pharmaceutical-grade excipients
    • Synthesized drug compounds pending formulation

    5. Laboratory and Electronic Cleaning Fluids

    Precision cleaning operations across laboratory, microelectronics, and fine instrument assembly use n-Hexane as a fast-evaporating solvent for degreasing, defluxing, and surface preparation. The material’s non-polar character enables removal of oil, waxes, and other low molecular contaminants without residue, provided hydrophobic surfaces and metals are treated. Facility managers install advanced local ventilation and solvent waste recovery, as service life and purity impact process control and occupational health risk profiles.

    Industry compliance standards

    • IPC-CH-65B (Cleaning and residue control in electronics assembly)
    • SAE AMS 1526C (Solvent cleaners for aircraft components)
    • RoHS Directive 2011/65/EU (Residue content impacts on electronics)
    • NFPA 30 (Flammable and combustible liquids code)

    Typical usage ratio

    • Direct application, neat or in blend, from 100% down to 30% with additional solvents; selection based on contaminant load and cleaning stage

    Downstream process integration

    • Fills ultrasonic cleaning tanks or automated wipes as primary solvent
    • Passes through filtration and distillation for reuse upon contaminant threshold
    • Employed in manual component cleaning or dipping lines prior to assembly packaging

    Final product types

    • Precision-cleaned printed circuit boards (PCB)
    • Cleared laboratory glassware and analytical equipment
    • Assembled electronic modules for consumer or industrial use

    6. Paint Thinner and Industrial Coatings

    Coatings formulators use n-Hexane in paint, varnish, and lacquer manufacturing for viscosity reduction, pigment dispersion, and rapid drying. Its volatility controls surface flow and leveling, especially in automotive, wood finishing, and metal protective coating sectors. Raw material supply must meet low moisture and peroxide content specifications to maintain color uniformity and shelf stability. Production lines incorporate closed-loop blending, solvent vapor recovery, and emissions abatement according to plant and jurisdiction requirements.

    Industry compliance standards

    • ASTM D875 (Paint and lacquer thinner specifications)
    • EU Directive 2004/42/EC (VOC content in coatings)
    • National Emission Standards for Hazardous Air Pollutants (NESHAP), US EPA
    • ISO 12944-5 (Protective paint systems for steel structures)

    Typical usage ratio

    • 5%–18% n-Hexane in total solvent fraction, dependent on coating viscosity specifications, climate of application, and application method (e.g., spray, brush, dip)

    Downstream process integration

    • Contained in solvent blending tanks along with resins, pigments, and additives
    • Added during milling, dispersing, and pre-filling bulk storage
    • Participates in coating application and subsequent oven or ambient curing

    Final product types

    • Automotive refinishing coatings and touch-up paints
    • Wood furniture lacquers and sealants
    • Metal anti-corrosive primers and top coats
    Free Quote

    Competitive n-Hexane prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    n-Hexane: Practical Value from the Manufacturer’s Floor

    What n-Hexane Means at the Source

    Every shift on our production line brings up new questions about raw materials—how to keep solvents pure, get yields up, and send out a product customers can trust. n-Hexane earns its keep across the plant and in hundreds of sites worldwide, serving as a trusted aliphatic hydrocarbon for extracting, cleaning, and manufacturing. Instead of empty talk, we approach this chemical with an attitude shaped by daily use and practical realities. Our n-Hexane, often referenced by model or batch code tied to real test data, consistently meets industry needs—whether it’s for pharmacy-grade extractions, edible oil processing, adhesives, or precision cleaning. We see the challenges that laboratories, processors, and industrial teams deal with; that’s what guides our production philosophy from the tanks up, not buzzwords.

    Production Experience Shapes Our Approach

    n-Hexane comes off the distillation columns with a clear, colorless appearance, a sharp odor, and realizes its value through consistency and chemical reliability. We run fractionation under strict controls because small impurities—n-heptane, isohexane, cyclohexane, trace aromatics—can change performance or safety characteristics. Our teams operate GC and liquid chromatography lines every batch, measuring purity levels often above 99%. Not every user cares about the last fraction of a percent, but for pharmaceuticals or specialty polymers, even faint impurities can derail results. Over the years, we have seen customers’ analytical results echo what we keep on file, and repeated tests in customer labs have matched ours. We avoid trading tales about “generic” product; our n-Hexane batch sheets stick to real measured outcomes.

    A batch labeled as “n-Hexane 99% min” or “n-Hexane, ISO grade” signals tight boiling point range and low water content, so solvent residues come off predictably during evaporation, and everything downstream runs as planned. For customers working in edible oil extraction, especially soybean or sunflower, residue tolerance sits just a sliver above zero. Food manufacturers run their own quality audits, but our results match up year after year. In the electronics sector, where solvent-based cleaning prepares delicate surfaces for further processing, traces of non-hexane hydrocarbons or moisture can short-circuit entire production runs. Back on our factory floor, regular crosschecks against international standards connect our take on quality with what industry actually demands.

    n-Hexane Use Cases Extend Beyond the Obvious

    Every month, requests for n-Hexane roll in from far beyond standard edible oil or adhesive production. We see formulators in the specialty chemicals world call for tighter purity or “anhydrous” n-Hexane when building blocks for high-grade lubricants and catalysts need clean reaction environments. Rubber and tire manufacturers specify low-aromatic content, because even one percent off-spec can alter the tack or cure of finished goods. Lab supply buyers discuss residue after evaporation—some want extra documentation for their chromatography solvents; others prefer bulk shipments to keep procurement cycles manageable. The questions we field—about solvent recovery, regulatory reporting, even trace benzene documentation—reflect real production demands, not theoretical use cases.

    Through decades in the field, we’ve watched large buyers, often from adhesives and coatings giants, shift to lower-odor models of n-Hexane. This led us to refine deodorization processes, since residual sulfur or aldehydic contaminants show up as issues in user facilities, despite never triggering regulatory alarms. For production partners in the pharmaceutical field, low peroxides and water content allow easier validation in GMP environments; our technical reports are built for audit trails, not just sales claims. Waste management teams look for details around flashpoint and evaporative loss, as some regions call for specific documentation under local chemical safety laws. Realistically, differences in fine print matter when management shifts from “on paper” conformity to real-world trouble-shooting.

    Seeing the Real Differences: n-Hexane and Its Cousins

    Some competitors pitch “hexane” as a family name, lumping together isohexane, cyclohexane, and commercial mixed alkane products. From a manufacturing position, we see these compounds diverge widely. Isohexane (2-methylpentane and other isomers) has a lower boiling point and a volatility profile that doesn’t track with straight n-Hexane. Cyclohexane—a ring structure, not a straight chain—offers quite different solubility, flammability, and handling hazards. In some extraction processes, these distinctions sound minor, but solubility limits and evaporation speed matter right on the shop floor and in analytical results. Blends sold as “hexane” in markets without regulatory teeth may float through at lower cost, but lack the batch-to-batch certainty critical in regulated environments.

    Our operators watch for tiny differences: n-Hexane evaporates faster than its branched or cyclic neighbors, making it favored where quick drying is essential—think circuit cleaning or polyester adhesives. Isomeric mixes keep more residue, show less solvency for non-polar substances, and can pack higher odor. n-Hexane’s boiling range sits roughly at 68°C—not too high to slow down distillation, not too low to disrupt recovery operations. Our prep teams follow these numbers closely; a spec sheet is only a summary. It’s the practical outcome in the customer’s process—easy recovery, minimal taste/odor in food extraction, predictable adhesive drying—that tells everyone here whether a run hit the mark.

    Specifications That Wear Their Value

    Because n-Hexane is a high-volume industrial material, lots of suppliers cut corners on product specs, convincing buyers that “hexane content” alone tells the story. We approach things from a chemical control perspective: water content, acidity, trace aromatics, and residue after evaporation all feature in batch certificates. Where a customer requests anhydrous material for critical reactions, we step up drying controls, including in-line molecular sieve traps, to hit requested moisture content below 50 ppm. For chromatography-grade or reagent-grade, purity goes up a notch. Tighter cut-off points in distillation push up cost but guard outcomes in sensitive work. We never downplay the safety elements—flashpoint, vapor pressure, and stability under storage must meet both legal requirements and the real challenges faced by those storing or using the solvent under demanding conditions.

    Specifications don’t come off the drawing board; they come from a mix of repeat feedback and years of on-the-ground troubleshooting. Take the edible oil fields, for instance. Detection of anisidine values or peroxide levels in extracted meals hinges on avoiding microleaks or contamination in the finished solvent. We’ve adjusted tank linings, revamped transfer processes, and updated test points at customer request—then published that data back to buyers. Chromatography users sometimes ask for detailed residual non-volatile content, since an extra tenth of a percent can interfere with runs. Our labs store reference samples for years, supporting customer claims or regulatory requests when questions hit six or 18 months later.

    Addressing Typical Concerns, Not Just in QA

    Plant operators and safety officers worry about handling n-Hexane for good reason—its flammable range, low flash point, and potent vapors pose real risks in both storage and use. Production engineers look at potential for vapor leaks, static discharge, and long-term health exposure. We’ve kept exposures low with closed-loop systems, vapor recovery, and careful monitoring. Stored drums and IBC tanks have to stay away from ignition points and receive regular inspection. In refineries, anti-static measures, double seals, and nitrogen blanketing all go in as standard process. Advice gets passed between facilities—what works during summer heat, how to control the smell, or prevent accidental mixing with incompatible substances like strong oxidizers.

    Solvent losses (sometimes called “evaporation shrinkage”) tick up in hot or poorly ventilated storage zones. We work with customers on monitored systems and capped pipeways to catch unnecessary losses, turning what used to be accepted as normal shrinkage into manageable numbers. For small buyers without onsite engineering, our field staff advises retrofits for storage and blending, often providing sample installation drawings or direct feedback from other users. Incident reports from outside firms get reviewed for root cause: off-spec batches from a few years back often linked to small tank valve leaks or contaminated transfer lines. Sharing these findings with customers—an honestly collaborative process—tends to prevent the same issue cropping up again elsewhere.

    Legislation and Sustainability: Realities, Not Just Trends

    The chemical industry faces a wave of new regulatory controls every decade. n-Hexane sits on various watchlists, because chronic inhalation at high exposure can trigger health effects, especially neurotoxicity with repeated misuse. We do not dismiss this. It pushes us to install stricter vapor controls, train staff in respiratory safety, and offer product stewardship sessions to downstream users. A customer-focused response means transparency: batch-by-batch test data, open SDS access, and help with local compliance forms. In oil extraction and food industries, non-volatile trace and cross-contaminant checks make their way into specifications as local regulators step up audits. Processors facing new regulations on solvent recovery or emissions can benefit from shared real-world solutions—such as tailored vapor capture, recycling units, or improved recovery ratios.

    Sustainability comes up more often in procurement meetings. n-Hexane, derived from petroleum, will not get a “green” label without real effort. We address this by improving recovery from recycling units, advocating closed-loop reuse, and—where feasible—supplying technical advice for substitution in less demanding roles. Not every user can switch overnight, but bulk handlers, regional processors, and even research labs get more from their deliveries when recovery rates go up. We maintain transparency on regional sourcing, batch origin, and potential for recycled content where supply chain conditions allow. Our advice: effective management beats blanket bans. Real reductions in solvent loss, plus tracking of waste endpoints and tighter recovery cycles, deliver more than just marketing victories—they answer real environmental and business pressures.

    Practical Solutions Arise from Real Dialogue

    No product, including n-Hexane, stays “one size fits all” as user needs evolve. Over years, the most meaningful progress has come from feedback loops: customers in vegetable oil plants asking for less odor; electronics assemblers reporting new residue issues; industrial users needing certification for export or meeting downstream chain-of-custody standards. Direct contact with end users—often on the actual plant floor—changes our practices far more than any remote guideline. We maintain technical points-of-contact for follow-up, not just for audits but for process improvement, worker safety, and troubleshooting.

    Compressing perennial feedback—requests for tighter spec, better documentation, flexible packaging—led to incremental process changes over time. Large-volume users get bulk tanker shipments while small labs appreciate sealed glass containers or lined drums. During transport, tank cleaning protocols, residue checks, and even secondary sealing measures come out of listening to buyers who manage processes at increasing pace and scale. After a railcar incident a decade back, we upgraded valves across the chain; when a European partner flagged regulatory shifts on aromatic content, we adjusted analytical reporting to exceed baseline compliance. Problem-solving—anchored in technical understanding, supply chain management, and day-to-day realities—keeps the product reliable, not promises in promotional copy.

    n-Hexane in the Real World: Beyond the Data Sheet

    After years of production, one fact is inescapable: the real value in n-Hexane rests in how it behaves through an end user’s process, not in technical data or “pure” claims stamped on a drum. High-spec, pharmacy-grade material might track across the analytical scale, but unless it delivers predictable results—clean extraction of oil without flavor/odor impact, complete solvent removal in adhesives, or precise separations in chromatography—it falls short. Our technical teams track not only outgoing purity, but also how the solvent interacts with extraction matrices, resins, and even waste filtration. Matching solvent recovery rates, analyzing evaporation curves, or supporting designs to minimize operator exposure all feed back into production decisions.

    Through decades of shipments across continents, seasonal changes, and production surges, practical know-how outweighs theoretical guarantees. Customers rarely worry about theory—they call when the solvent leaves a stain, tastes linger in extracted foods, or cleaning power falls short in the field. We respond from experience, not scripts: reviewing handling logs, double-checking batch moisture, or running new comparison analyses to support claims. A trusted product lives up to its batch sheets, but it also answers user complaints with technical fixes, not avoidance. When a custom-grade n-Hexane needed to address regulatory hurdles in medical device manufacturing, we changed purification and added distillation steps, then built supporting paperwork for on-site inspectors. These real-world results shape every subsequent production run.

    Looking Forward: Continuous Improvement

    The next chapter for n-Hexane will depend on both evolving regulation and shifting real-world needs. As user industries search for higher efficiency, better safety, and new extraction technologies, we keep up not by claiming universal expertise, but by making small, sometimes invisible, improvements at every step. Efficient heat recovery, routine waste tracking, leak prevention, and new vapor capture systems have grown out of day-to-day troubleshooting, not outside mandates. As customer expectations move toward ever-lower impurity, more robust documentation, and wider application support, we recognize that sustaining quality means investing in both people and technology.

    Our production teams—backed by R&D, QA, and customer feedback channels—address practical details: batch consistency, safe handling guidance, and matching shifting industrial requirements. No two users see n-Hexane in quite the same light. Whether a buyer runs deep, high-purity extractions or routine adhesive blending, we shape our approach to support practical outcomes. Each batch delivered reflects not just what comes off our columns, but decades of shared learning with end users worldwide.