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N-Hexanal

    • Product Name N-Hexanal
    • Alias caproaldehyde
    • Einecs 202-768-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    373561

    Chemical Name N-Hexanal
    Cas Number 66-25-1
    Molecular Formula C6H12O
    Molar Mass 100.16 g/mol
    Appearance Colorless liquid
    Odor Pungent, grassy
    Boiling Point 130 °C
    Melting Point -57 °C
    Density 0.815 g/cm³ (at 20 °C)
    Flash Point 27 °C
    Solubility In Water Insoluble
    Vapor Pressure 14 mmHg (at 20 °C)
    Refractive Index 1.410 (at 20 °C)
    Logp Octanol Water 1.78
    Un Number 2372

    As an accredited N-Hexanal factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Clear glass bottle, 100 mL, with tight-sealing screw cap, hazard labels, and printed chemical information for n-Hexanal, securely boxed.
    Shipping N-Hexanal should be shipped in tightly sealed containers, away from heat, sparks, and open flames, as it is a flammable liquid. It must be clearly labeled, stored upright, and protected from physical damage during transport. Compliance with local, national, and international hazardous material regulations is required.
    Storage N-Hexanal should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. Keep the container tightly closed and protected from direct sunlight. Use corrosion-resistant containers, and ensure the storage area is equipped with proper spill containment measures. Store at temperatures below 25°C to maintain stability and prevent decomposition.
    Application of N-Hexanal

    Applications of N-Hexanal in Industrial Manufacturing

    N-Hexanal serves as a valuable intermediate for a range of specialty industrial sectors. Our direct production supports stable supply, consistent purity, and reliable compliance in technical downstream applications. Below, we detail real manufacturing uses across several industries, with technical guidance on specification, ratios, processing steps, and final product integration.

    1. Flavors and Fragrances Synthesis

    Perfume and aroma ingredient manufacturers use N-Hexanal in aldehydic notes, green fragrances, and for specialty fruit flavors. It participates as a key building block in the formulation of synthetic flavors for food, beverages, and cosmetics, and as an intermediate for citronellol, hexyl cinnamic aldehyde, and other complex scents. Careful control over concentration, chain purity, and reaction purity is essential due to high downstream regulatory demands. Formulators select N-Hexanal based on reactivity, minimal off-notes, and compatibility in esterifications and acetalizations, often using batch-specific approvals and validated supply chains to maintain compliance, especially where intended for food or personal care exposure.

    Industry compliance standards

    • IFRA Standards (International Fragrance Association)
    • EU Regulation (EC) No 1334/2008 for flavoring substances
    • US FDA 21 CFR 172.515 (flavoring substances and adjuvants)
    • ISO 9235 (Aromatic Natural Raw Materials – Vocabulary) for trace component declaration

    Typical usage ratio

    • 0.01–0.3% of total perfume compound; food flavor dosing based on final regulatory limits (typically below 5 ppm in finished foods)
    • Adjusted by target aroma intensity and matrix formulation

    Downstream process integration

    • Direct addition in mixing/reactor stages for aldehyde blends
    • Precursor for hydrogenation to hexanol or condensation to C12 aldehydes
    • Esterification for fruity or green-floral flavor molecule synthesis
    • Analytical QC for purity (GC, GC-MS) prior to blending

    Final product types

    • Fine fragrance bases (aldehydic, green, marine notes)
    • Food and beverage fruit flavorings
    • Air care and cosmetic fragrance systems
    • Intermediates for higher functionalized aromatic ingredients

    2. Pharmaceutical Intermediate Synthesis

    The pharmaceutical sector relies on N-Hexanal as a chain-building block for the production of specialty intermediates, APIs, and certain excipients. Manufacturers use it in multi-step synthesis of heterocyclic cores, acyclic building blocks for statins, pheromones, or in the preparation of alkyl side-chain modified molecules. Conformance with GMP and thorough impurity profiling are essential, as final drug quality and registration documentation may require traceability by lot number and full impurity spectra. The material undergoes secondary processing, such as Grignard or Wittig reactions, where purity, minimal water, and low peroxide content are critical.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF, EP, JP relevant monographs for intermediates (if applicable)
    • 21 CFR Part 210/211 (US FDA cGMP regulations)
    • REACH registration for supply in EU countries

    Typical usage ratio

    • Stoichiometric input in multi-step synthesis, typically 0.5–2.0 molar equivalents relative to coupling partners
    • Ratio adjusted according to stage yield and side chain requirements

    Downstream process integration

    • Introduction at alkylation or condensation step
    • Used as aldehyde coupling partner for heterocycle construction
    • Distillation or solvent extraction for intermediate isolation
    • QC via HPLC, NMR, and Karl Fischer titration for water control

    Final product types

    • Statin side chain intermediates
    • Active ingredients for pheromone-based products
    • Building blocks for chiral drug substances
    • API precursors with C6 alkyl side chains

    3. Agrochemical Synthesis

    Producers of crop protection agents and insect pheromones employ N-Hexanal as a precursor for straight-chain alcohols, carboxylic acids, and related intermediates. Manufacturing processes depend on precise control of chain length and reactivity for downstream oxidation, esterification, or reduction steps. Selected lots must achieve consistent low aldehyde by-products and match chain purity specifications outlined in agrochemical dossiers. Integrators use N-Hexanal in processes with stringent residue, migration, and toxicity controls. Proper storage and transportation under controlled conditions help retain reactivity for further processing.

    Industry compliance standards

    • FAO/WHO Specifications for Agrochemical Active Ingredients
    • Regulation (EC) No 1107/2009 (EU Plant Protection Products)
    • US EPA FIFRA (Federal Insecticide, Fungicide, and Rodenticide Act)
    • ISO 1750 (Common names for pesticides)

    Typical usage ratio

    • 0.1–1.5 molar equivalents dependent on target synthesis (e.g., 1:1 for alcohol/acid intermediates, up to 1.5:1 for pheromones)
    • Adjusted for product yield and downstream reaction specificity

    Downstream process integration

    • Input at oxidation (to hexanoic acid) or reduction (to hexanol) step
    • Acylation or esterification for pheromone construction
    • Isolation by distillation; purity monitored by GC analysis
    • Used under closed processing to minimize emissions

    Final product types

    • Insect sex pheromone formulations
    • Herbicide and fungicide precursors
    • Agrochemical active esters and acids
    • Growth regulator intermediates

    4. Plasticizer and Polymer Additive Manufacturing

    Specialty plasticizer and polymer manufacturers use N-Hexanal as an intermediate for aliphatic plasticizers, chain modifying agents, and processing stabilizers, particularly in flexible PVC and certain engineering plastics. Producers convert it, through further oxidation or condensation reactions, into hexyl phthalates or caproate esters, which offer unique migration resistance and cold flexibility to final polymers. Formulation labs monitor both input purity and residual aldehyde content to ensure no odor impact or migration into packaged goods. Strictly controlled storage, weighing, and dosing protocols help maintain consistency in batch and continuous production lines.

    Industry compliance standards

    • EU REACH Regulation (EC) 1907/2006
    • US FDA 21 CFR 177.2600 (Rubber articles for repeated use, for additives in polymeric materials)
    • EN ISO 9001:2015 (Quality Management Systems for process and product traceability)
    • Directive 2002/72/EC (Food contact plastics, additive purity requirements)

    Typical usage ratio

    • Input conversion ratio typically 0.8–1.2 equivalents for esterification with acid partners
    • Plasticizer blending in final resin: 5–25% weight fraction depending on flexibility and migration limits

    Downstream process integration

    • Batch-fed or continuous feed to esterification reactors
    • Monitored by process analytics (GC, IR) for completion of aldehyde reaction
    • Integration at blending or compounding stage in downstream resin manufacture
    • Product sampling for residual impurity testing

    Final product types

    • Hexyl phthalate and caproate plasticizers
    • Polymer chain extenders and flexibility modifiers
    • PVC film, sheet, and wire insulation
    • Flexible packaging material additives

    5. Specialty Lubricant and Oil Additive Production

    Lubricant oil formulators use N-Hexanal as a synthesis step for tailored esters and additives that enhance viscosity index, pour point, and solvency properties of industrial oils. The raw material participates in multi-step synthesis of alkylated additives including anti-wear agents and pour point depressors. Manufacturing operations monitor aldehyde conversion and eliminate unreacted residues to prevent oxidation or odor in final lubricants. Final esters must demonstrate strong compatibility with base oils and meet detailed performance specifications for sector certification.

    Industry compliance standards

    • ASTM D4485 (Standard for Engine Oil Additives)
    • SAE J183 (Engine Oil Performance Classification)
    • ISO 9001:2015 for traceability in specialty additive production
    • REACH registration for oil additive chemicals

    Typical usage ratio

    • Reactive input for ester synthesis: 1:1 molar with acid blend (5–15% in additive concentrate)
    • Blending levels in finished lubricant: 0.5–2.5% w/w for specialty performance fluids

    Downstream process integration

    • Input to esterification or alkylation reactors for additive construction
    • Blending with base stock oils after final purification
    • In-line QC and removal of trace aldehyde residues before packaging
    • Evaluation against pour point and viscosity targets

    Final product types

    • Synthetic lubricant esters and solvent oils
    • Cold flow modifiers for industrial oils
    • Anti-wear and dispersant oil additives
    • Metalworking fluid and gear oil additive components
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    Certification & Compliance
    More Introduction

    N-Hexanal: A Manufacturer's Insight

    Looking Closely at N-Hexanal—Our Direct Experience

    At our plant, we know N-Hexanal by more than its numbers and formulas. Everyday, teams handle this six-carbon aldehyde with its familiar, sharp scent. The model we produce—pure and consistent—moves through countless checks before reaching any drum or flask. The value of this compound in the chemical world grows from direct observation on the production floor. N-Hexanal, C6H12O as chemists write it, appears simple at first glance, but over years of work we’ve watched how details in its manufacture and finishing shape everything from customer satisfaction to downstream process reliability.

    Each batch we prepare leans on our internal standards. We apply distillation steps with care so the purity never falls below expectations. For N-Hexanal, this usually means keeping impurities at bare minimums—our typical output reaches more than 98% purity. Achieving that purity without frequent rework depends on clean feedstocks, skilled operators, and well-maintained reactors. The product emerges as a clear, colorless liquid with a powerful, grassy aroma; anyone walking the floor notices it once a seal or hose fitting loosens. We store and ship N-Hexanal under a blanket of nitrogen, working continuously to limit oxidation. The experience confirms that close attention to how we store and move the product avoids unwanted off-odors that could harm its use in downstream formulations.

    On the Floor: What Sets Our N-Hexanal Apart

    Decades in chemical manufacturing shaped how we look at differences between products sharing the same chemical label. Our N-Hexanal differs most in its stability and odor quality. Years back, we noticed customers sensitive to even trace decomposition products found in shipments from volatile supply chains. Unlike traders blending or reselling from various origins, we keep every step of manufacture in-house, with a closed loop on raw material quality, distillation, and storage. From this, we see clearer liquid, milder odor, and fewer customer complaints about yellowing or unexpected reactivity. These differences save years for compounding labs and fragrance blenders. A refined separation and careful monitoring of reaction conditions keep byproduct levels under control. Any time a drum leaves the gate, a batch number traces back to raw material intake and the core details of that day’s production.

    Lab technicians using our N-Hexanal often point out that their columns clog less, and their aroma tests match standards better. Our reactors never switch arbitrarily between aldehydes, meaning residues from other syntheses never sneak in. By running standardized campaigns, we avoid contamination by higher molecular weight aldehydes or residual solvent remains that could spoil the final outcome. Maintaining dedicated infrastructure for N-Hexanal production stands as one of our key differences compared to generalists who run many chemicals through the same line with quick washes in between.

    Reflecting on N-Hexanal’s Use in the Real World

    N-Hexanal remains best known among fragrance, flavor, and intermediate synthesis sectors. Perfume chemists prize its unmistakable green, leafy notes—one whiff stirs immediate thoughts of cut grass on a spring day. Our customers rely on this natural signature when blending for freshness and top notes in cosmetics or air care. Food additive companies, always alert for safe, straightforward molecules, have adopted N-Hexanal as a flavor component, providing that slight tart crispness needed for some fruits and vegetables in both natural and artificial formulations.

    Industrial syntheses call for aldehydes with consistent behavior, and N-Hexanal works as a key building block. Our product sees the most volume as an intermediate in making herbicides, plastics additives, and even pharmaceutical side chains. The need here is predictability; any reactive byproducts from poorly controlled manufacturing trigger expensive failures. Over years, feedback loops with our end users led us to refine our purification and handling, catching and removing less obvious contaminants that frustrated some large-scale organic syntheses. This brings down overall defect rates in downstream reactions. Our engineers frequently review chromatogram and color index data, updating controls so every drum offers the same strong behavior in the lab and at scale. Reliability at the manufacturing level changes the entire economics for those relying on N-Hexanal in multi-ton quantities.

    Understanding the Safety and Handling Reality

    Working with aldehydes, especially those with a strong odor and moderate reactivity like N-Hexanal, means prioritizing engineering controls and staff experience. No handbook replaces what seasoned operators learn from years on the production line. A clear liquid at ambient temperatures, N-Hexanal flashes aggressively if heated or left open to atmosphere. It irritates eyes and mucous membranes—the brisk, cutting scent reminds anyone nearby to wear goggles and gloves, whether decanting from glass or steel. Over time, even small leaks can corrode soft metals and affect nearby composites, so we keep our transfer hoses double-braided and replace gaskets before their rated limits.

    Oxidation remains the persistent concern. Where some suppliers rely on batch tests alone, we monitor oxygen content during each stage. Our lines run under nitrogen from the first transfer out of synthesis, minimizing peroxide formation and discoloration that could arise in open air. We learned from early missteps that even a few hours exposure shifts hue and brings out off-flavors—results that risk customer rejection. Once the product enters storage, we cycle nitrogen headspace frequently, testing seals after any movement or pump transfer. Under these controls, the shelf life extends comfortably past regulatory guidelines, and our oldest drums show the same organoleptic profile as the freshest lot.

    Troubleshooting and Process Improvements from the Manufacturer’s Bench

    Making N-Hexanal at scale throws up technical snags that the market rarely sees. The main challenge comes from the starting alcohols or paraffins, which rarely run free of minor isomers or unsaturated byproducts. These impurities, even in tiny amounts, cause variations in the final odor—and for fine fragrance or specialty flavors, these off-notes break formulations. Over the years, we invested in custom fractionation equipment, including high-efficiency packed columns and advanced control systems. These cut back on re-distillation cycles that once drove up costs and eroded the bottom line.

    Operators flag anomalies in the fraction as soon as they surface on the daily checks. Rather than relying solely on titration or broad chemical tests, we keep both GC-MS and sensory panels active, comparing product output to historical benchmarks. Chemically, N-Hexanal tends to headspace volatilize abruptly if the weather shifts cold to hot; anticipating such batch-to-batch swings takes regular calibration of condensers and rapid switchovers during shoulder seasons. A single missed swing can affect an entire truckload, costing both time and reputation. The lessons learned here extend directly into how we package: drums are filled with an inert blanket, labeled by production sequence, and sealed with tamper-evident systems.

    Waste and emissions management for N-Hexanal call for real experience. Early in our history, we tried to shortcut solvent recovery, which led to higher VOC emissions and stricter regulatory attention. Switches to closed-loop systems and on-site solvent reclamation brought both compliance and real cost savings. Every ton produced gets tallied for total environmental output, and any losses traced back to root cause. This reporting lets us improve batch yields and refine our environmental controls, matching what auditors seek and what our community asks of local industry.

    Learning from Customer Feedback and Field Applications

    Direct end-user feedback touches every aspect of our N-Hexanal offering. Early on, requests came for custom packaging—smaller pails for lab-scale trials, or large isotainers for continuous processing. By solving for these practical constraints, not just purity, we meet the needs of users refining their own production setups. In fragrances, a repeat customer needed N-Hexanal sourced only from certain feedstocks to match an accepted aroma profile. Meeting such needs required shifting to regionally sourced alcohols for one batch, tracking the results closely before making it part of ongoing production for that client. These hands-on changes, backed by production records and chemical analysis, established lasting trust.

    Where complaints surfaced—such as slightly off shades or barely detectable metallic tangs—our lab team pivoted to more stringently monitor trace iron and copper carryover from valves and fitting corrosion. Simple changes in cleaning regime and switch to stainless steel wherever possible made measurable differences, both for quality and for reducing residue in finished blends. After updating these procedures, we noted a marked drop in negative reports and sent samples to those same previously dissatisfied customers for reevaluation. These cycles of improvement tie laboratory results and shop-floor controls directly to changes demanded by the marketplace, not just internal standards or regulatory thresholds.

    Some of the most revealing improvements started not from the lab, but the warehouse. Complaints about drum hardening or crystallization during unseasonably cold transport highlighted a need for new insulation strategies. Ops teams collaborated with logistics to update shipping containers, pre-warming stocks before winter dispatches. Results could be tracked: fewer solidification incidents, easier handling for end users, and more predictable inventory turnover. None of these solutions emerged from a manual; they arose as hands-on answers to practical hurdles reported by those opening drums miles away from our gates.

    Comparing N-Hexanal with Alternatives: A Manufacturer’s Perspective

    On paper, N-Hexanal fits among a family of straight-chain aldehydes. Customers sometimes ask why not switch to similar options—pentanal, heptanal, or even synthetic blends that mimic green notes. Years working directly with these alternatives reveals the subtle but telling differences. Take pentanal: it is more volatile, with a sharper, less pleasant aroma that disappears quickly in open air. Heptanal drifts sweeter and waxier, lacking the clean crispness of N-Hexanal in finished fragrance bouquets. These chemical cousins, although sharing some functions, fail to deliver the same combination of stability, purity, and olfactory impact in precision blending.

    While a formulator could substitute in multi-component synthetic blends, the consistency and single-source traceability that pure N-Hexanal gives outweighs theoretical cost cuts. With secondary compounds, end-product testing becomes unpredictable and regulatory filings grow more cumbersome. Trade customers, especially in markets like Japan or the EU, routinely specify not just the IUPAC name, but how the material was produced and stored, favoring established vertical manufacturers over spot traders. Our experience confirms that investment in single-stream production and transparent batch control leads to less hassle for users—fewer certificate of analysis (CoA) disputes and better acceptance across audits.

    Commitment to Process Safety and Compliance

    Manufacturing experience taught us the high stakes of process safety with N-Hexanal. The molecule’s reactivity, while limited compared to short-chain aldehydes, causes fires and exposures when handled carelessly. We run continuous monitoring for both vapor concentrations and possible leaks—years of handling built up an instinct for when a line or tank might need attention, but sensors and data back up each decision. Staff train for immediate containment procedures: spill kits, emergency showers, remote shutoff. Standard PPE includes not only gloves and goggles but face shields and jackets, especially during drum transfers.

    Regulatory authorities pay special attention to chemical manufacturers handling aldehydes at scale. We keep all documentation open for inspection, from batch records and emissions data down to the minor tweaks that moved one reaction parameter by a fraction of a degree. This data-driven approach not only keeps us compliant, it gives confidence to downstream users who often audit our facility in person. Suppliers with open documentation and visible process controls finish at the front line for repeat business in regulated markets.

    Insurers, internal EHS staff, and outside auditors test scenarios for spill response, fire suppression, and environmental protection. Tracking near-miss events, even minor vapor escapes or imperfect seals, allows us to adjust operating procedures continuously. This proactive culture, shaped over years of manufacturing, builds real resilience for both our company and the community surrounding our facility.

    Continuous Improvement from Direct Line Experience

    Most improvements to our N-Hexanal production didn’t start as top-down mandates; they came from a maintenance tech or a night-shift supervisor fixing recurring nuisances. Decanting valves got switched out for more chemical-resistant types after corrosion cut short replacement cycles. Heating jackets and temperature alarms found their way onto critical lines not because of a safety manual, but from observing minor losses during winter startups. Plant tours with incoming engineers often turn into brainstorming sessions, and good ideas head straight to pilot projects. Small wins add up over thousands of batches. We document every measurable change, using both technical metrics and input from shop-floor staff. Yield rises and product quality moves upward, batch by batch.

    The partnership between our lab and process teams means any uptick in chromatographic impurities kicks off a real-time investigation. We’ve traced negative shifts back to seemingly minor changes in raw stock—feed alcohols with new minor contaminants—enabling a rapid fix and clear communication with our supply partners. This on-the-ground connection, where lab data and operations knowledge blend, lets us solve problems before they snowball into customer issues.

    Product quality gets checked at several points, never just at final packing. We developed custom test panels to check not only for major impurities, but also for any deviation in odor, color, or reactivity compared to reference lots. This rigorous approach reflects pride in our role as a producer, not just a shipper—our name on the drum means something to everyone in the building, and everyone involved in its journey from plant to customer.

    Meeting Modern Demands Around Sustainability and Supply Stability

    In today’s market, producers face ongoing pressure to keep both quality and environmental footprint within tight specs. Sustainability claims must follow from real plant practice, not marketing logos. For N-Hexanal, this means investing in closed-loop waste handling and energy recovery. Early efforts to reduce flaring and cut solvent emissions came before regulations forced us; keeping a close relationship with local environmental groups and public regulators paved the way for faster adoption of green metrics. These measures drove an overall reduction in total chemical footprint while meeting both client and community expectations.

    Supply disruptions challenge every manufacturer sooner or later. We responded by dual-sourcing critical inputs, qualifying alternative transport routes, and maintaining real-time inventory tracking. Bulk storage tanks with real-time temperature and level data provide early warning of potential disturbances, whether from upstream logistics or shifting market demand. Sourcing models adapt based on actual use trends, not just historical patterns, letting us stay responsive regardless of spikes in global commodity cycles. Our emphasis stays on delivering stable supply to all contract clients, especially those planning months ahead for regulated sectors like pharmaceuticals and food additives.

    Collaborative Effort—People Behind the Process

    Many outside the industry imagine chemical plants running as faceless automatons, but our daily operations prove otherwise. From control room operators monitoring reactor temperatures in real time, to warehouse crews labeling each shipment, every person adds value to each kilogram of N-Hexanal that leaves our site. We invest in regular technical training, cross-training for backup coverage, and support for long-term career growth. This investment pays back by reducing error rates, catching deviations early, and building pride in product stewardship. Over time, the plant’s reputation grows not just from technical achievements, but from honest relationships with buyers, auditors, and the broader industrial community.

    Partnership with end users matters as much as technical controls. Our staff regularly visit client sites to understand shifting needs, troubleshoot application questions, and supply expert insight into compatible blends or usage limits. These visits often reveal new application methods or process tweaks we later integrate into our own manufacturing methods. They also keep us grounded—anyone producing specialty chemicals at scale learns humility from the inevitable surprises found in real-world applications.

    Real World Responsibility and Looking Ahead

    Years of hands-on production highlighted the need for accountability—not only to customers, but to local communities and broader markets. As process chemists and plant managers, we stay vigilant over product safety, environmental compliance, and workforce health, known directly from the plant floor rather than from boardroom summaries. We treat product stewardship as an ongoing commitment; from controlling every reaction and shipment detail, to improving air and water quality around the facility.

    Looking ahead, we work closely with regulators, technology partners, and industry associations. As product requirements shift—tighter purity, lower emissions, more rigorous traceability—we adapt proactively. The lessons and habits built over decades of real chemical manufacturing guide us each day to deliver the best N-Hexanal possible to those who depend on it, wherever their operations may be.