Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

N-Butyric Acid

    • Product Name N-Butyric Acid
    • Alias Butyric Acid
    • Einecs 202-310-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    980105

    Chemical Name N-Butyric Acid
    Other Names Butanoic acid
    Chemical Formula C4H8O2
    Molecular Weight 88.11 g/mol
    Cas Number 107-92-6
    Appearance Colorless liquid
    Odor Unpleasant, rancid butter-like
    Boiling Point 163.5°C
    Melting Point -7.9°C
    Density 0.958 g/cm³ (at 20°C)
    Solubility In Water Miscible
    Pka 4.82
    Flash Point 72°C (closed cup)
    Vapor Pressure 1.5 mmHg (at 20°C)
    Refractive Index 1.399 (at 20°C)

    As an accredited N-Butyric Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing N-Butyric Acid is supplied in a 500 mL amber glass bottle with a secure screw cap and a prominent hazard warning label.
    Shipping N-Butyric Acid should be shipped in tightly sealed, leak-proof containers, compliant with local and international regulations for corrosive substances (UN No. 2820, Class 8). It must be stored and transported in a cool, well-ventilated area away from incompatible materials, with appropriate hazard labeling and documentation for safe handling and emergency response.
    Storage N-Butyric acid should be stored in a cool, dry, and well-ventilated area away from heat sources, open flames, and direct sunlight. Keep the container tightly closed and clearly labeled. Store away from incompatible materials such as oxidizing agents and strong bases. Use corrosion-resistant containers, and ensure proper secondary containment to prevent leakage or spills. Avoid inhalation of vapors.
    Application of N-Butyric Acid

    Applications of N-Butyric Acid in Industrial Manufacturing

    As a core upstream manufacturer focused on the stable supply of N-Butyric Acid, we support industrial partners in a range of highly specific downstream processing segments. Our material supports efficient production processes for food flavor compounding, feed additive synthesis, pharmaceutical active ingredient production, and biopolymer manufacturing. Each application scenario below details practical integration methods, precise regulatory frameworks, and formulation engineering considerations at the industrial scale.

    1. Food Flavor and Fragrance Formulation

    Flavor houses and food processing manufacturers use N-Butyric Acid to develop natural and artificial buttery, cheesy, and dairy flavor notes for confectionery, bakery, snack, and beverage applications. It serves as a building block for flavor esters, contributing essential aroma components in highly controlled blending operations. Strict adherence to international food additive safety and purity is enforced across procurement, processing, and quality assurance checkpoints.

    Industry compliance standards

    • FAO/WHO Codex Alimentarius (GSFA – General Standard for Food Additives)
    • EU Regulation (EC) No. 1334/2008 on flavorings
    • United States FDA 21 CFR 172.515 (Flavoring Substances and Adjuvants)
    • China GB 2760-2014 (National Standards for Food Additive Use)

    Typical usage ratio

    • 0.005–0.05% in finished flavor formulations; specific dosage determined by desired flavor strength, target food matrix, and local regulations

    Downstream process integration

    • Dissolved or premixed into flavor oil blends prior to blending with carriers and emulsifiers
    • Utilized in esterification step to generate flavor esters (e.g., ethyl butyrate, methyl butyrate) for subsequent blending into flavor bases

    Final product types

    • Butter, cheese, and cream flavor bases for ice cream and bakery
    • Snack seasoning compounds (chips, popcorn)
    • Beverage and candy flavors (fruit drinks, hard candy, chewing gum)
    • Processed cheese analogues and filled chocolates

    2. Animal Feed Additives and Gut Health Promoters

    Premix producers, feed integrators, and feed additive formulators incorporate N-Butyric Acid to enhance gut morphology, nutrient uptake, and pathogen resistance in livestock and aquaculture. Its bioactivity drives intestinal epithelial development and beneficial microbial balance, making formulation and stability parameters critical from blending to pelletizing.

    Industry compliance standards

    • European Feed Additives Register (EC Regulation 1831/2003)
    • FAMI-QS Code (Feed Additive and Premixtures Quality System)
    • AAFCO Official Publication (United States)
    • China Feed Additive Regulation GB/T 18673

    Typical usage ratio

    • 0.02–0.30% depending on animal species, lifecycle stage, and feed composition (e.g., broilers at 0.05–0.15%; swine at 0.10–0.20%; aquaculture up to 0.30% in compound feed)

    Downstream process integration

    • Homogenized with vitamin and mineral premix during micro-ingredient batching
    • Added prior to or during pelleting/extrusion for mash, pellet, or crumble feed types

    Final product types

    • Poultry starter and finisher feeds
    • Swine grower rations
    • Dairy calf milk replacers
    • Aquaculture compound feeds (shrimp, tilapia, trout)

    3. Pharmaceutical Intermediate for Active Pharmaceutical Ingredient (API) Synthesis

    API manufacturers leverage pharmaceutical-grade N-Butyric Acid as a precursor or intermediate in the synthesis of specialty compounds, including butyric acid esters, sodium butyrate, and anti-inflammatory active molecules. High purity and trace impurity controls are paramount during reaction, isolation, and purification steps to achieve pharmacopeial-grade end products.

    Industry compliance standards

    • USP–NF (United States Pharmacopeia–National Formulary)
    • European Pharmacopoeia (Ph. Eur.) monographs for excipients and APIs
    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • cGMP (Current Good Manufacturing Practices) – FDA, EMA guidance

    Typical usage ratio

    • As an intermediate, reaction stoichiometry may range from 1–3 molar equivalents relative to starting material; precise amounts based on target molecule design and process yield optimization

    Downstream process integration

    • Charged directly into reaction reactors for esterification, amidation, or salt formation during multistep organic synthesis
    • Undergoes purification steps such as vacuum distillation or crystallization as dictated by target compound purity specifications

    Final product types

    • Sodium butyrate and other butyrate salts for oral or parenteral preparations
    • Histone deacetylase (HDAC) inhibitors
    • Prodrugs and excipient grades for regulated drug formulations
    • Pharmaceutical-grade intermediates for custom synthesis pipelines

    4. Biopolymer and Bioplastic Precursor Synthesis

    Producers specializing in sustainable materials employ N-Butyric Acid as a fermentation substrate or chemical precursor for the production of polyhydroxyalkanoates and specialty biodegradable polymers. It readily integrates into biological and chemical process streams, contributing key carbon units to achieve tunable polymer flexibility and degradation profiles.

    Industry compliance standards

    • OECD Guidelines for Biodegradability
    • EN 13432 (Packaging – Requirements for packaging recoverable through composting and biodegradation)
    • ISO 17088:2012 (Specifications for compostable plastics)
    • REACH Registration for raw material sourcing and processing safety

    Typical usage ratio

    • Feeding rate into fermenters or chemical reactors: 1–8 g/L, depending on production strain, target polymer properties, and process yield targets

    Downstream process integration

    • Continuously or batch-fed into bioreactors for microbial PHA/PHB synthesis
    • Participates as a co-monomer source in polycondensation for developing custom bioplastic grades

    Final product types

    • PHA (polyhydroxyalkanoate) and PHB (polyhydroxybutyrate) biodegradable resins
    • Flexible film-grade compostable plastics
    • Molded biopolymer packaging solutions
    • Green adhesives and sustainable material blends
    Free Quote

    Competitive N-Butyric Acid prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    N-Butyric Acid: A Manufacturer’s Perspective on Precision, Quality, and Usage

    Understanding N-Butyric Acid from the Source

    At our facility, producing N-Butyric Acid feels less like routine manufacturing and more like a carefully orchestrated process. Picture the distinctive, pungent scent wafting through the air—a marker of pure, undiluted butyric acid with well-recognized chemical behavior. This acid, catalogued by many as C4H8O2, stands out not solely for its odor but for its versatility and purity. With years of hands-on experience, we have learned the subtleties and challenges that come with every batch, where minute differences in process conditions, catalyst selection, and raw material handling shape the final quality.

    Our N-Butyric Acid generally presents itself as a colorless liquid, sometimes tinged slightly yellow if undiluted. The odor is unmistakable—sharp, penetrating, and, for those new to the business, unforgettable. Many chemists recognize that characteristic smell from their first encounter, associating it immediately with fatty acid chemistry. We do not just bottle and ship—each lot gets its own story, traced back through every production step for consistency.

    Manufacturing Process and Quality Control

    Our method relies on the oxidation of butyraldehyde, chosen for reliable conversion rates and manageable by-products. Over time, we've optimized reaction temperatures and catalyst loads, which allows us to reach purity levels of 99% or greater for laboratory and food-grade requests. Some applications ask for less stringent specs, but our line rarely drops below 98%. It’s not just a number; that last percent can mean the difference between full solubility for a flavor chemist and clouding or precipitation in a formulation.

    Trace impurities, such as isobutyric acid or water, get tracked by our in-house GC and Karl Fischer titration. Consistency in product means both our internal team and our customers can expect the same result, drum after drum. Any deviation appears quickly in the supply chain, and we take pride in pinpointing and fixing the root cause before a shipment sees the outside world.

    Specifications and Models in Actual Production

    In practice, we rarely get away with just one “N-Butyric Acid.” Customers downstream call for distinct grades, depending on their purpose. For feed industry clients, a purity between 98-99% flows well and blends consistently into animal feedstock. For pharmaceutical and food applications, refinement steps eliminate trace aldehydes and moisture, bumping up the purity and decreasing off-notes that can mask target flavors. Typically, we fill orders by net weight—most often 200 kg drums. Tanker shipments operate on demand for high-volume clients who have the proper receiving setups.

    We mark each lot with distillation point (within 163-165°C at atmospheric pressure), acid value, color index, and water content. These figures are not formalities. Feed additive makers and flavor houses pore over these details, as a mismatched boiling point or excessive water content disrupts entire production runs on their end. After working closely with application chemistry teams, we adapted our process years ago to control and minimize these variations, investing in better column design and tighter temperature control.

    N-Butyric Acid Usage: Real-World Applications

    N-Butyric Acid enjoys a varied career as a building block. It pops up in animal feed as a gut health enhancer—veterinarians and feed formulators swear by its efficacy for piglets and calves struggling through dietary transitions. It finds a second life mingling with esters, finding agency in the flavor and fragrance industry. As a manufacturer, we often field questions from artisans and chemists surprised to discover that the same acid, so strong and off-putting in concentration, gives buttery and cheesy notes at low dilutions.

    The food industry leans heavily on butyric acid esters for flavorings. Manufacturers use the raw acid to create esters that replicate natural dairy flavors and add authentic notes to processed cheese, butter, baked goods, and even certain candies. Over the years, we’ve seen a shift in requirements—now, more orders specify minimal off-flavors and absence of residual catalysts, the kind of details that only a direct manufacturer can answer for, given close control of raw materials and process reagents.

    In agriculture, butyric acid’s antimicrobial properties support farm biosecurity programs. The acid’s volatility demands robust handling protocols—we have learned, often the hard way, how a small vapor leak in shipment can spark a chain of logistics headaches. To this day, we provide technical support for safe transfer methods, vapor mitigation, and handling at the client’s site.

    Chemical synthesis uses N-Butyric Acid as a precursor for making plasticizers, cellulose acetate butyrate, and specialized pharmaceuticals. Each of these industries needs tight compositional tolerances: even minute increases in water content or color can throw off a catalyst system or taint a finished polymer. We staff our QA/QC lab with chemists who understand these downstream impacts because, as a producer, we live with the consequences of batch failure.

    Differences Compared to Other Compounds

    We hear plenty of confusion from new formulators and purchasing agents about the differences between N-Butyric Acid and the isobutyric, valeric, or caproic acids they see in catalogs. The straight-chain structure of butyric acid sets it apart from its branched or lengthier relatives, both in volatility and functional behavior. As a manufacturer, we see this play out in process requirements—N-Butyric Acid distills cleanly at a lower temperature than isocaproic acid, and it resists polymerization far better than isobutyric acid when stored under typical warehouse conditions.

    Volatility brings unique challenges and opportunities. N-Butyric’s high vapor pressure at room temperature (over 2 mmHg at 25°C) means careful sealing at every drum opening. This also explains its rapid action as a flavoring molecule and its effectiveness as a feed additive with quick-release requirements. Isobutyric acid, by contrast, packs a softer odor profile and less persistence in the open air, which limits its direct use in flavorings but finds fans in polymer chemistry.

    The solubility profile of butyric acid matches most simple carboxylic acids. It blends well with alcohols, ethers, and water, but remains significantly less viscous than the heavier chain acids. Most clients find that, in direct contact, N-Butyric Acid’s reactivity in esterification or amidation provides cleaner conversion yields due to its clean chain structure and manageable side reactions.

    In recent years, feed and food industry standards have tightened scrutiny of even low-level impurities: isobutyric acid, methyl ethyl ketone, or even residual catalyst. Our role as the original producer makes it possible to provide lot tracking, assay certificates, and true cradle-to-shipping documentation—something not all distributors offer. Customers dealing direct with us get accurate impurity profiles, which can be pivotal in troubleshooting performance in their end-use formulations.

    Challenges in Production and Market Supply

    Making and selling N-Butyric Acid at scale brings its own set of puzzles, especially for those of us behind the equipment. The odor, known to drift far beyond the premises, keeps us working closely with community leaders and regulatory agencies. Over time, we have installed sophisticated scrubber systems and containment areas. Each year, we audit our emission control plans and update process equipment to align with environmental limits and to respect our neighbors who have gotten direct whiffs of production runs in years past.

    On the market side, global demand waxes and wanes with livestock production booms, growth in processed foods, and cycles in the chemical intermediate trade. Spikes in demand for feed supplements ripple through our supply chain with little advance notice. Price swings follow the availability of feedstock aldehydes and energy costs. Years ago, we learned never to cut corners during price upswings by compromising on purification—chasing market swings leads to diminished trust. Instead, we prioritize stable output and communication with long-standing customers, knowing that consistency keeps partnerships alive.

    Transportation represents another battleground. Not many carriers want to handle N-Butyric Acid regularly, given the potential for smell contamination and the tough clean-up if leaks happen. We have invested in dedicated tankers and schedule routine maintenance and cleaning to prevent residues from transferring between loads. These behind-the-scenes logistics keep our product from becoming an unwelcome guest in the carrier’s next load of plastic resin or edible oil.

    Responsibility, Safety, and Transparency

    Handling butyric acid, especially as a concentrated liquid, puts a premium on safe practice. Early on, we saw that mishandling leads to ruined containers, hurt workers, and, not infrequently, lost productivity from forced shutdowns. Over the years, we’ve introduced hands-on training, robust leak detection, and strict personal protective equipment requirements. We adapt guidance as regulations and best practices evolve, and we keep an ear to emerging industry consensus on worker exposure and environmental health.

    Transparency builds trust—whether for new buyers or the old hands calling for a quick spec check, we provide real testing data, not repackaged “minimum standard” declarations with every shipment. Customers have asked about odd lot numbers, source raw materials, and even our carbon handling policies. We see these inquiries as the kind of accountability that keeps our facility sharp. Regulators check in often, but so do buyers with acute deadlines and sensitive applications. From our view, the closer we work with end-users, the fewer the surprises.

    Product Innovation and Outlook

    Over the past decade, we have invested in new reactor designs and process monitoring, not purely for yield but for the increased demand for “clean label” inputs in food and feed. End customers expect not only a consistent acid, but a product with a clear chain of custody, assured low residue levels, and up-to-date sustainability disclosures. Recently, customers have begun asking about alternative feedstocks—bio-based production methods rather than petrochemical. We have responded with pilot runs of fermentation-based butyric acid and continue to optimize for competitive costs and throughput.

    Flavor chemists challenge us with tighter impurity specs year after year—trace metals, sulfur content, and even enantiomeric purity, though N-Butyric Acid is achiral. Some even request custom blends for esters, which requires us to maintain flexibility on the plant floor and provide technical advice on how to solve production bottlenecks.

    The feed industry, especially in regions tightening antibiotic use, taps into acidifiers like butyric acid to fill the gap. Our team often sits down with formulation specialists, hammering out ways to guarantee palatability and minimize nutrient interactions. For this, impurities, residual moisture, and even low-level color matter, as pigment traces signal compromised purity in feed and food chains.

    Paths Forward: Collaboration and Quality Commitment

    Manufacturing N-Butyric Acid continues to force innovation, vigilance, and active collaboration every year. The challenges—odor management, energy cost swings, new regulatory frameworks—are never static. Demand keeps us flexible, responding to everything from animal nutrition breakthroughs to next-generation flavor esters or coatings. By keeping our process knowledge close and quality commitments clear, we help downstream partners trust the contents of every container.

    On the operations side, we still prioritize investment in monitoring and human training. Each shift yields new opportunities for improvement, whether optimizing a distillation column or understanding variances in raw aldehyde batches. These improvements are informed by feedback from customers facing hurdles with application chemistry or regulatory reviews. Our ability to pivot, test, and retest, means solutions do not trickle down from abstract policy—they build on years of facing both expected and unanticipated obstacles head-on.

    Looking ahead, we expect the marketplace to push for sustainability, lower emission profiles, and deeper integration between manufacturers and end-users. As a producer, staying ahead means not just selling a molecule, but backing every load with insight, traceability, and a willingness to troubleshoot new puzzles alongside our customers. Those who use N-Butyric Acid in their formulations count on more than a delivery—they count on expertise built from years on the production line, from practical answers to complex questions, and from a commitment to honest, direct communication in a changing world.