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N-Amylamine

    • Product Name N-Amylamine
    • Alias 1-Pentanamine
    • Einecs 205-685-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    878381

    Chemical Name N-Amylamine
    Cas Number 110-58-7
    Molecular Formula C5H13N
    Molar Mass 87.16 g/mol
    Appearance Colorless liquid
    Odor Ammoniacal, fishy
    Boiling Point 104 °C
    Melting Point -70 °C
    Density 0.765 g/cm3 at 20 °C
    Solubility In Water Miscible
    Vapor Pressure 59 mmHg at 25 °C
    Flash Point 16 °C (closed cup)
    Refractive Index 1.406 at 20 °C
    Autoignition Temperature 285 °C
    Synonyms 1-Aminopentane

    As an accredited N-Amylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing N-Amylamine is packaged in a 1-liter amber glass bottle with a tight-sealing cap, labeled with safety and hazard information.
    Shipping N-Amylamine is shipped as a hazardous chemical, typically in steel drums or approved containers. It must be kept tightly sealed, in a cool, well-ventilated area, away from sources of ignition and incompatible materials. Shipping follows regulations such as DOT, IATA, or IMDG, and containers are clearly labeled with appropriate hazard warnings.
    Storage N-Amylamine should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as acids and oxidizers. Keep the container tightly closed and properly labeled. Use corrosion-resistant containers, preferably made of glass or certain plastics. Protect from moisture and direct sunlight. Ensure emergency equipment is easily accessible in the storage area.
    Application of N-Amylamine

    Applications of N-Amylamine in Industrial Manufacturing

    N-Amylamine serves as a key intermediate for a range of specialized industrial processes. As an experienced manufacturer, we support sector-specific requirements with focus on regulated, well-characterized downstream applications.

    1. Agrochemical Synthesis: Herbicide and Pesticide Intermediates

    N-Amylamine is integral in the production of selective herbicides and pesticide active ingredients, especially for the synthesis of substituted anilines and heterocycles. Its primary amine group enables nucleophilic substitution and amidation reactions crucial for constructing agrochemical molecules. During production, exact amine incorporation influences biological activity, stability, and degradation profiles, which must comply with crop protection standards. Downstream operators strictly monitor residual amine content after reaction and purification. All handling requires closed systems to prevent environmental release as per local regulations.

    Industry compliance standards

    • FAO/WHO Specifications and Evaluations for Agricultural Pesticides
    • REACH Regulation (EC) No 1907/2006 for raw material registration and safe handling
    • ISO 9001-certified Quality Management Systems for traceability
    • Integrative Good Manufacturing Practices (GMP) for active ingredient intermediates

    Typical usage ratio

    • 10–25% N-Amylamine by reactant mass, adjusted based on molar stoichiometry and target molecule structure
    • Small deviations in excess amine ratio depending on desired conversion and downstream purification efficiency

    Downstream process integration

    • Charged during active ingredient synthesis step, often amidation or alkylation processes
    • Reacted under inert atmosphere at 60–120°C depending on partner substrate reactivity
    • Residual amine removed via distillation or extraction before formulation
    • Batch and continuous reactors used based on plant throughput

    Final product types

    • Phenoxy acid herbicides
    • Triazine-based pesticides
    • Substituted aniline insecticides
    • Growth regulator intermediates

    2. Pharmaceutical Intermediate Manufacturing

    N-Amylamine is utilized in active pharmaceutical ingredient (API) synthesis, especially in the construction of alkylated amine moieties. Its chain length and amine functionality tailor pharmacokinetic properties such as solubility and bioavailability. Stringent impurity control and validated analytical methods govern all pharmaceutical production environments. Drug master files require data on amine purity, absence of unreacted starting material, and environmental impact control during syntheses. Real-time monitoring during processing ensures compliance with regulatory and patent standards for bulk drug manufacturing.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients
    • USP–NF, Ph. Eur., JP monographs for starting materials
    • 21 CFR Part 211 Current Good Manufacturing Practice for Finished Pharmaceuticals
    • FDA and EMA requirements for raw material control and change notification

    Typical usage ratio

    • 5–20% of total reactant charge in coupling or alkylation reactions, typically determined by target molecular structure and desired yield optimization
    • Ratio fine-tuned for minimizing residual solvents and avoiding excess starting material in API critical process steps

    Downstream process integration

    • Added during primary or secondary amination steps in bulk API synthesis
    • Reaction under controlled pressure (1–3 bar) with solvents such as ethanol, toluene, or MEK
    • In-line GC and HPLC used to monitor conversion and impurity levels
    • Subsequent crystallization or extraction steps to isolate target intermediates

    Final product types

    • Bulk pharmaceutical intermediates for CNS drugs
    • Anti-infective agent intermediates
    • Alkylated API building blocks
    • Amide/amide-forming drug scaffolds

    3. Flotation Agent Formulation for Mining

    N-Amylamine is used to manufacture cationic flotation agents that enable selective separation of silicates and alumina from ore products. Its hydrophobic alkyl chain enhances collector properties, while the amine group promotes strong attachment to mineral surfaces. Formulators adjust the ratio and dosing regimen based on ore composition and pH sensitivity. During operation, precise amine dosing increases recovery rates and purity of concentrate after separation. Environmental compliance and worker safety demand closed circuit handling and residual amine recovery systems as per mining laws.

    Industry compliance standards

    • ISO 14001 for environmental management in mining operations
    • National environmental emissions regulations (e.g., US EPA TSCA Title VI, China MEE)
    • REACH Annex XVII restricted substances obligations
    • Safety Data Sheet protocols under GHS CLP

    Typical usage ratio

    • 0.05–0.3% by mass of ore processed, calibrated based on mineralogy and flotation cell conditions
    • Precise dosing necessary to balance flotation efficacy and wastewater amine residues

    Downstream process integration

    • Dosed into flotation cell as pure liquid or water-based dissolved concentrate at controlled pH (9–11)
    • Mixing and aeration conditions optimized for collector coverage and froth stability
    • Post-separation residual collection recycles amines where feasible
    • Effluent treated for residual amine via hydrolysis or activated carbon filtration before release

    Final product types

    • Concentrated iron ore
    • Bauxite concentrates
    • Phosphate ore
    • Industrial silica and feldspar concentrates

    4. Epoxy and Polyurethane Curing Agent Manufacturing

    N-Amylamine acts as a primary amine hardener in the production of epoxy resin and polyurethane system curing agents, imparting specific open times and mechanical properties to end-use coatings, adhesives, and foams. Its reaction speed and by-product profile enable custom formulation for demanding industrial flooring, coatings, and composite part manufacturing. The amine’s inclusion impacts pot life, surface tack, and chemical resistance of the cured system. Manufacturers ensure compliance with product safety, workplace exposure limits, and chemical labeling standards throughout blending and QC procedures.

    Industry compliance standards

    • ASTM D5363 Standard Specification for Epoxy Resin Adhesives
    • ISO 9001 for quality control in chemical blending
    • EU REACH pre-registration and notification for use in reactive resins
    • OSHA 29 CFR 1910.1200 for hazard communication in chemical workplaces

    Typical usage ratio

    • 3–18 phr (parts per hundred resin) in epoxy hardener formulations
    • Adjusted based on desired curing rate, compatibility with polyol components, and application temperature

    Downstream process integration

    • Blended into multi-component hardener systems under nitrogen to minimize moisture pickup
    • Metered addition to pre-react or form adducts prior to packaging
    • Monitored for amine blush and exothermicity during QC batch validation
    • Final blend filtered to remove particulates before drum or IBC filling

    Final product types

    • Industrial epoxy floor coatings
    • Polyurethane foams
    • Corrosion-resistant pipeline coatings
    • Automotive structural adhesives

    5. Textile Auxiliary Synthesis (Antistatic and Wetting Agents)

    N-Amylamine is employed as a building block in cationic textile auxiliaries. Its primary amine enables production of surfactants, antistatic agents, and wetting chemicals tailored for synthetic and blended fibers. Chemical structure directly influences affinity for polyamide and polyester surfaces, fluid uptake, and static dissipation properties. Manufacturers execute targeted alkylation or quaternization following environmental permitting rules. Auxiliary formulations undergo textile safety testing and end-use simulation before delivery to finishing mills or dye houses.

    Industry compliance standards

    • OEKO-TEX Standard 100 for restricted substance content
    • ZDHC MRSL (Manufacturing Restricted Substances List)
    • ISO 14001-certified environmental management during surfactant synthesis
    • EU REACH registration for use in textiles

    Typical usage ratio

    • 5–20% as raw reactant in wetting agent and softener synthesis by total batch mass
    • Formulation level in textile baths typically 0.1–2.0% based on fiber load and desired performance

    Downstream process integration

    • Enters alkylation step during cationic surfactant synthesis
    • Reacted with alkyl halides or acids under controlled pH
    • After neutralization and purification, auxiliary is blended into liquid or powder form for textile plant use
    • Batches sampled for functional group content, pH, color, and residue compliance

    Final product types

    • Nonionic and cationic antistatic agents
    • Synthetic fiber wetting agents
    • Softeners for polyester fabric
    • Fiber lubricants for high-speed weaving
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    Certification & Compliance
    More Introduction

    N-Amylamine: A Closer Look from the Manufacturer’s Perspective

    Introduction and Our Experience Producing N-Amylamine

    As a chemical manufacturer with decades of hands-on process time behind us, our relationship with N-Amylamine runs deep. N-Amylamine—known by its proper chemical name, pentan-1-amine or 1-aminopentane—has quietly proven itself as a flexible aliphatic amine in both industrial and research settings. We have seen many cycles in the market, and through those, N-Amylamine retains a core role in fine chemical synthesis, agrochemical formulation, pharmaceutical intermediates, and resins, all thanks to its distinct molecular structure.

    Because we are responsible for every production stage, we keep purity front and center. N-Amylamine’s consistency in our batches sets a standard that allows downstream users to avoid common headaches linked with off-grade amines: contamination, odor issues, and unpredictable reactivity. Based on our production line audits, control of byproducts like amides and secondary amines reduces unwanted side reactions—a real advantage when you’re scaling up or need reproducible results in sensitive syntheses.

    Model and Specifications Shaped by Production Experience

    Our typical output delivers N-Amylamine in a liquid state, with purity consistently exceeding 99%. We’ve received requests for lower moisture and reduced secondary amine content, which have driven us to refine both distillation cut points and gas-phase drying systems. We produce and store the compound in dedicated vessels to preserve this purity, because trace exchange between alkyl amines can mean costly downtime for our customers’ subsequent operations.

    Unambiguous labeling and analytical transparency matter as much to us as they do to our buyers. Over time, we noted that some confusion in the field comes from overlapping nomenclature or mixed packing grades. Our feedback-driven documentation lists not just assay values, but also detailed impurity profiles such as water, residual solvent, and amide content. This enables R&D chemists and procurement leads to cross-check requirements before shipment, which minimizes avoidable returns and ensures formulations stay on schedule.

    Where N-Amylamine Finds Strong Utility

    The applications for N-Amylamine have evolved, but the compound’s core chemistry has made some jobs easier. In agricultural chemistry, formulators favor it for alkylation and acylation as a building block for herbicides and plant growth regulators. From our vantage as supplier, we see how its primary amine group reacts predictably—without the steric hindrance found in branched-chain or bulkier amines. Researchers value this consistency when developing new molecules.

    Pharmaceutical process teams in particular depend on tight impurity windows. They use N-Amylamine both as a blocking agent and as a source of the pentyl side chain. We’ve adapted our cleaning protocols to meet stringent migration limits and traceability standards set by regulatory authorities. That means every batch shows clear logs of origin, chain of custody, and analytical data. A single unforeseen impurity can set back a months-long synthesis, so we built our quality program to address this from the start.

    We often field requests from the plastics and resins sector as well. N-Amylamine interacts well with isocyanates and epoxy precursors without forming heavy byproduct loads or causing foaming issues. Epoxy hardener manufacturers point out that compared to shorter or highly-branched amines, pentylamine’s mid-length alkyl chain contributes a manageable evaporation profile, making it less troublesome to incorporate in open settings.

    How N-Amylamine Differs from Related Amines

    Our work in amine chemistry highlights real differences between N-Amylamine and its close relatives like n-butylamine, n-hexylamine, and cycloalkylamines. Handling properties, reactivity, and even workplace safety can shift with a single carbon on the chain. N-Amylamine strikes a balance: less volatile and less pungent than n-butylamine, easier to contain but still liquid at room temperature, more flexible in downstream chemical modification than longer chains.

    We have noticed operational improvements in facilities that switched from n-butylamine to N-Amylamine. For instance, solvent recovery runs cooler, and ambient air handling shows reduced exposure incidents. N-hexylamine offers lower volatility, but customers tell us its slower reaction rate and higher boiling point push up utility costs, especially when performing amide coupling or acyl chloride reactions under vacuum.

    Structural variations also cause downstream performance changes. Branching or aromaticity in amines can interrupt clean end-product crystallization or polymer crosslinking. N-Amylamine’s linear chain ensures it reacts fully in most nucleophilic substitution and addition-elimination processes, without leaving unpredictable residues. This has been validated in both laboratory trials and full-scale syntheses for agrochemical actives and API intermediates.

    Supporting Market Demands and Regulatory Compliance

    Yearly audits from customers and third-party agencies push us to double down on surface integrity, purity, and safety controls. We invested heavily in well-grounded environmental safeguards at our facility—packed scrubbers, closed nitrogen blanketing, and high-sensitivity amine monitors—to prevent occupational hazards and off-site emissions. The workplace impact isn’t academic: a small release of volatile lower-chain amines can spark community complaints and safety concerns for operators. N-Amylamine’s lower vapor pressure than shorter-chain peers simplifies compliance with air quality standards, easing permitting and community relations efforts.

    Making N-Amylamine at scale means reacting 1-bromopentane or 1-chloropentane with ammonia or operating reductive amination lines, all requiring diligent handling of hazardous intermediates and careful waste recovery. Our operations team draws experience from each campaign to tweak charge order, reflux cycles, and cooling rates to minimize off-spec conversion: this means less waste, lower risk, and a cleaner product for customers. Many market shifts—especially those driven by new pharmaceutical filings or crop protection launches—put extra pressure on our quality system. We respond with more frequent monitoring, renewed calibration, and proactive technical dialogue with end users.

    Downstream Applications: The Real World Perspective

    Field chemists in the rubber and polymer sector prefer our high-purity N-Amylamine because side-reactivity and discoloration can make or break a production run. For example, in rubber vulcanization, a clean amine source prevents tacky or uneven cured products. Even small amide or secondary amine impurities can slow curing or lead to off-color batches. Users across coatings, textile auxiliaries, and surfactant synthesis cite similar priorities. Our feedback channels bring these real-life process concerns directly to our technical team, where in-plant changes are made in close response to user feedback.

    Academic and industrial researchers cite the reagent’s performance in reductive amination, especially when pursuing pentyl derivatives with minimal byproduct complexity. Low secondary amine content saves cleanup work and predictive side-product analysis, giving projects a faster path to publication or commercial launch. In specialty chemical syntheses, such as plant extract derivatization or sensor functionalization, an even response from the amine’s nucleophilicity is necessary—our process testing shows N-Amylamine consistently outperforms branched or hindered amine alternatives in reaction yield and final product purity.

    Packaging, Logistics, and Storage: Practical Realities

    In practice, packing matters as much as the product itself. We fill drums and intermediate bulk containers under dry, inert conditions to avoid hydrolysis or product darkening. Long-haul customers request nitrogen-purged drums or pressure-rated containers to safeguard the amine during ocean or cross-border shipping. Amine odors linger, and prior field complaints about permeation resulted in tighter liner specs and pump upgrades. Most bulk buyers now prefer seamless transfer systems to reduce workplace exposure, and we support these installations with fit-checks and compatibility documentation.

    Questions about shelf life often come up. With the right seals, pure N-Amylamine maintains its performance profile for over a year, though direct sunlight and heat accelerate breakdown. We designed our storage handling protocols and dispatch schedules to balance inventory turnover with customer demand surges. Monthly stability testing feeds into our batch-release schedules, tracking color, assay, and water content. For smaller-lot research users, our team offers single-use packaging on request, reducing the need for local repacking and supporting hassle-free lab work.

    Frequently Asked Questions from Our End Users

    We engage regularly with both large-scale formulators and research scientists, fielding technical questions—from reaction performance to application safety. Most users want specifics on volatility, handling risks, and compatibility with other reactants. We developed fast-reference guides based on recurring customer questions, including guidelines for spill response, thermal stability, and mixing order in multi-component reactions.

    Our technical support team, staffed with chemists from manufacturing, not just customer service, supports direct troubleshooting. This means a user can get advice from someone who has clocked hours with the same product on a shop floor, not just relaying a spec sheet. The questions we field—about solvent choices, precautions in scale-up, or odor management in plant settings—shape our internal processes. Each answer converts into a better product, reduced rework, and fewer headaches all around.

    Solutions to On-the-Ground Challenges

    A direct line between manufacturing and client use means we spot challenges early. Handling N-Amylamine, especially in hot climates or cramped facilities, presents workplace comfort and safety demands. In response, we upgraded drum valves and shifted shipping schedules to minimize product exposure at loading bays. Hot weather transports prompted us to develop a technical bulletin on minimizing amine odors and safely venting containers. Frequent dialogue with plant engineers led us to enhance our ammonia scrubber efficiency and invest in state-of-the-art monitoring for vapor containment.

    Regulatory oversight grows stricter every year, especially where finished goods touch the food or pharma supply chains. When European and international environmental benchmarks shifted, we fine-tuned process vent controls and ran tests on lower-volatility blends, even though this meant reconfiguring our tank farms and documentation practices. Practical solutions emerged from in-house pilots: faster loading, improved tank blanketing, and better personal protective equipment for kettle operators. Routine retraining of our shop floor and logistics staff means users receive a product handled with fresh diligence every time.

    The Difference Manufacturer Involvement Makes

    As the original producer, we bear responsibility, not just for the molecule itself but for its journey and every hand it passes through. Traders and distributors might pass along a drum and an invoice, but only manufacturers know the journey from reactors to tanks to validated shipments, and the real lessons come from batches that missed the mark. Our ability to proactively tune specifications or reroute supply ensures users don’t get caught off-guard by supply-chain hiccups or surprise impurity spikes.

    Through collaboration with both longstanding and new customers, we learned what really matters extends beyond the stated spec. Reliability, clear communication, and a willingness to tweak the process bring genuine value. Year after year, we adjust kettle charging sequences, distillation tower configurations, and storage conditions in response to a stream of process data and customer feedback. Every process tweak, every cycle of product testing, and every technical exchange with users loops back into continuous improvement.

    Innovation and R&D: Lessons from the Factory Floor

    Efforts to fine-tune N-Amylamine stem from both field failures and R&D breakthroughs. While large batch campaigns deliver the majority of volume, small-scale research projects occasionally inspire new process routes or purity improvements. Our chemists and operators share formal process reviews after each campaign, using real yields and field-tested application results to identify upgrade paths. This habit cuts waste, lowers energy use, and makes for a cleaner, more sustainable manufacturing footprint.

    Users sometimes propose greener syntheses or alternative solvents. We track these asks, and regularly trial both bio-based starting materials and energy-sparing steps. Recent pilot runs on catalytic hydrogenation cuts have saved significant utilities and reduced byproduct load by measurable margins. Environmental regulators and multinational buyers increasingly insist on product stewardship, prompting us to invest in analytical tools that characterize trace impurities and product life-cycle impacts. The result—smarter manufacturing and a safer, more predictable chemical for all stakeholders.

    The Role of N-Amylamine in a Dynamic Chemical Market

    N-Amylamine’s value isn’t static. As global chemical standards and downstream industries evolve, requirements on reactivity, cleanliness, and supply reliability become ever more exacting. We encounter shifts toward digital documentation, blockchain traceability, and predictive maintenance in our reactors, all driven by a need for transparency and rapid troubleshooting. The best solutions have come from pairing real-world plant feedback with technical problem solving—elements that only come from deep roots in manufacturing, not intermediary commerce.

    Industry move cycles—pharma launches, new agrochemical registrations, polymer standard updates—trigger demand spikes and new spec requirements. During these transitions, direct manufacturer relationships help customers adapt formulations and vet impurities with speed. We emphasize robust communication streams, documented lot histories, and up-to-date safety dossiers. This real-time flexibility underpins long-term supplier-client trust, and cements manufacturer accountability as more than a sales slogan.

    Conclusion: Why Source N-Amylamine from Chemical Manufacturers

    Choosing to source chemicals directly from hands-on producers bridges experience, innovation, and on-the-ground troubleshooting. N-Amylamine captures this advantage with a product profile shaped by years on factory floors, chemistry benches, and logistics crossings. End-user direction, not just regulatory mandate, has driven specification, packaging, and transparency improvements. We remain closely connected to the everyday realities of plant rooms, laboratories, and warehouses—where the true performance and challenges of N-Amylamine unfold.

    Each batch, every quality check, and every customer conversation reflects a two-way investment and a real commitment to building trust. This responsibility can’t be replicated by traders or resellers—and it’s one reason why a direct relationship with the manufacturer shapes greater predictability, confidence, and ongoing improvement in every drop of N-Amylamine that reaches a mixer, reactor, or laboratory bench.