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N-Aminoethylpiperazine

    • Product Name N-Aminoethylpiperazine
    • Alias AEP
    • Einecs 203-865-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    154381

    cas_number 140-31-8
    iupac_name 1-(2-Aminoethyl)piperazine
    molecular_formula C6H15N3
    molar_mass 129.20 g/mol
    appearance Colorless to pale yellow liquid
    density 0.982 g/cm3 (at 20°C)
    melting_point -17°C
    boiling_point 221°C
    solubility_in_water Miscible
    flash_point 120°C (closed cup)
    odor Ammonia-like
    refractive_index 1.498
    viscosity 14.6 mPa·s (at 25°C)

    As an accredited N-Aminoethylpiperazine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500 mL N-Aminoethylpiperazine is packaged in an amber glass bottle with a secure cap, labeled with hazard and handling information.
    Shipping N-Aminoethylpiperazine should be shipped in tightly sealed containers, clearly labeled, and packed to prevent leaks or spillage. Transport must comply with relevant hazardous materials regulations, including appropriate documentation and safety labels. Avoid extreme temperatures and ensure the chemical is kept away from incompatible substances during transit. Handle with suitable personal protective equipment (PPE).
    Storage N-Aminoethylpiperazine should be stored in a tightly closed container in a cool, dry, well-ventilated area, away from incompatible substances such as strong oxidizers and acids. Ensure the storage area is equipped to handle spills and provides protection from physical damage. Avoid exposure to heat and moisture, and label the storage container clearly with content and hazard information.
    Application of N-Aminoethylpiperazine

    Applications of N-Aminoethylpiperazine in Industrial Manufacturing

    As a direct manufacturer, we supply N-Aminoethylpiperazine (AEP) to global industrial clients across multiple sectors. Our technical and QC teams optimize grades and batch consistency for integration into strictly regulated downstream processes. We support advanced application development through reliable supply and technical documentation.

    1. Epoxy Curing Agents for Adhesives and Coatings

    Major epoxy system formulators in automotive, aerospace, and industrial electrical insulation use AEP as a polyamine co-curing agent. Its secondary and primary amine groups provide both rapid initial set and thermal-resistance in two-component and solvent-free epoxy formulations. Process engineers adjust the loading based on targeted gel time, final mechanical properties, and substrate materials.

    Industry compliance standards

    • REACH (EC 1907/2006), Annex XVII for chemicals in coatings
    • RoHS Directive (2011/65/EU) for restricted substances in electronics adhesives
    • ASTM D638-22 for mechanical testing of cured resins
    • ISO 9001:2015 for process validation in adhesives production

    Typical usage ratio

    • 5–15% w/w based on total resin in standard bisphenol-A epoxies
    • Adjustment based on temperature and application thickness
    • Lower ratios for low-viscosity primer resins
    • Higher ratios in structural bonding or potting compounds

    Downstream process integration

    • Batch addition directly to the resin prior to mechanical mixing
    • Continuous dosing for high-throughput automated lines
    • Post-addition QA sampling to confirm amine/epoxy ratio
    • Final pack-off in two-component dispensing systems

    Final product types

    • Structural adhesives for automotive assembly and electronics
    • Protective and anti-corrosive floor coatings
    • Encapsulated transformer and PCB components
    • Epoxy-based maintenance and repair kits

    2. Corrosion Inhibitor Synthesis in Oil and Gas Production

    AEP enables formulation of water-soluble and oil-soluble corrosion inhibitors used in upstream and midstream petrochemical operations. Downstream formulators react AEP with fatty acids, phosphonates, and aldehydes to produce finished inhibitors. Its polyamine backbone enhances adsorption onto metal surfaces, protecting critical process equipment under high temperature and sour gas conditions.

    Industry compliance standards

    • API RP 14E for materials in oilfield equipment
    • OECD Guideline 301 for biodegradability assessment in oilfield chemicals
    • TSCA (Toxic Substances Control Act) for chemical approval in the USA
    • REACH (EC 1907/2006) SDS and exposure scenario requirements

    Typical usage ratio

    • 10–25% w/w in corrosion inhibitor blends
    • Ratio varies based on tubing metallurgy and fluid composition
    • Optimized by field trials for injection/waterflood systems
    • High concentrations for severe H2S or CO2 service

    Downstream process integration

    • Quaternization with carboxylic acids or polyethylene glycol
    • Post-synthesis blending with solvents for ready-to-use packages
    • Pilot-scale compatibility evaluation before mass deployment
    • Batch QA by phase separation and active amine titration

    Final product types

    • Pipeline and wellbore corrosion inhibitor concentrates
    • Drilling mud additives for downhole protection
    • Lubricant additive packages for gas compressors
    • Water treatment chemicals for desalination plants

    3. Intermediate in Polyamide and Polyurea Synthesis

    Polymer manufacturers utilize AEP as a chain extender and crosslinker in specialty polyamide and polyurea production. Its aliphatic amine functionality reacts cleanly with diisocyanates and carboxylic acids, yielding polymers with adjustable mechanical strength and chemical resistance. Application engineers precisely meter AEP to achieve targeted molecular weight and flexibility in engineering plastics and elastomers.

    Industry compliance standards

    • FDA CFR 21 177.1590 for food-contact polyamides
    • EU 10/2011 for plastics in food packaging
    • ISO 7822 for polyurea elastomeric linings
    • ISO 9001:2015 for polymer QC systems

    Typical usage ratio

    • 1–10% mole ratio to total diisocyanate in polyurea systems
    • 3–8% w/w additive loading in PA-6-based copolymers
    • Lower levels for rigid plastics; higher for flexible elastomers
    • Adjustment by viscosity and target polymer end group

    Downstream process integration

    • Pre-blending in polymerization kettles with monomer feed
    • Inline dosing within reactive extrusion lines
    • QC sampling of molecular weight distribution post-polymerization
    • Granulation with masterbatch colorants for further molding

    Final product types

    • Polyurea spray coatings for automotive and pipeline
    • Engineering polyamides for electrical connectors
    • Elastomeric rollers for printing and conveyance
    • Specialty nylon films for flexible food packaging

    4. Chelating Agent Precursor in Water Treatment Chemicals

    AEP serves as a key starting amine in the synthesis of chelating and sequestering agents formulated for industrial water treatment. Manufacturers react it with carboxylic or phosphonic acids to produce stable metal ion sequestrants. These agents improve boiler and cooling system performance, prevent scale, and ensure compliance with environmental discharge limits on heavy metals.

    Industry compliance standards

    • EN 12123 for water treatment chemical composition
    • NSF/ANSI 60 for drinking water system additives
    • OECD 303A for environmental degradation profile
    • ISO 14001:2015 for responsible manufacturing

    Typical usage ratio

    • 15–35% content in chelating agent synthesis feed
    • Final agent dosed 1–10 ppm in treated water
    • Ratio based on metal concentration, water hardness, temperature
    • Adjusted for target scale and corrosion control efficiency

    Downstream process integration

    • Batch or continuous reaction with phosphonic acid derivatives
    • Purification by solvent extraction and crystallization
    • QC testing by ion chromatography and titration
    • Final packaging for liquid concentrate or granular form

    Final product types

    • Phosphonate-based water softeners
    • Heavy metal sequestrants for discharge compliance
    • Scale inhibitor blends for cooling towers and evaporators
    • Domestic and industrial boiler water additives

    5. Synthesis of Pharmaceutical Intermediates

    The pharmaceutical sector employs AEP as a protected amine scaffold in the synthesis of active intermediates for antihypertensive, antiviral, and CNS-targeted drug candidates. Its ready reactivity with acyl, alkyl, and protective groups streamlines multi-step reactions. Manufacturing chemists optimize batch addition to balance throughput and impurity profile in accordance with GMP standards.

    Industry compliance standards

    • ICH Q7 for GMP manufacturing of pharmaceutical intermediates
    • USP/NF Monographs (where applicable to APIs)
    • EU GMP EudraLex Volume 4, Part II for active ingredient production
    • FDA 21 CFR Part 211 for finished dosage intermediates

    Typical usage ratio

    • Stoichiometric or slight excess (1–1.2 eq) based on target functionalization
    • Ratio determined by molar requirements of specific API synthesis
    • Excess for byproduct clearance in protected intermediate routes
    • Strict batch records of consumed and recovered material

    Downstream process integration

    • Charge into jacketed glass-lined reactors for amidation or alkylation
    • Work-up via phase separation and multiple washing stages
    • Purification by recrystallization or flash chromatography
    • Release to downstream API synthesis only after full QC clearance

    Final product types

    • API intermediates for third-generation antihypertensives
    • Key coupling units for anti-viral drug candidates
    • Protected amines for central nervous system agents
    • Fine chemical intermediates for contract synthesis organizations

    6. Dye and Pigment Intermediates for Textile Chemicals

    AEP reacts with chromogenic groups and aromatic aldehydes in the creation of cationic and reactive dye intermediates used in textile and paper industries. Chemical synthesis labs design unique colorfast molecules by stepwise alkylation and cyclization involving AEP, achieving improvements in wash fastness and hue intensity in finished colorants.

    Industry compliance standards

    • Oeko-Tex Standard 100 for restricted dyestuff substances
    • ISO 105 C06 for wash fastness of colorants
    • BfR Recommendations XIV for colorants in contact with food packaging
    • REACH Appendix XVII for commercial pigment safety

    Typical usage ratio

    • 10–30% of amine component in stepwise dye synthesis
    • Adjusted in tandem with aldehyde and coupling reagent input
    • Specific ratios defined by targeted chromophore
    • Lower ratios in pastel dye ranges; higher for strong color builds

    Downstream process integration

    • Charge into high-shear reactors for condensation steps
    • Post-coupling neutralization and purification via filtration
    • Granulation for solid pigment concentrates or stabilization in dispersions
    • Batch QC for tint strength, hue position, and impurity content

    Final product types

    • Cationic and reactive dyes for synthetic fiber processing
    • Azo pigment intermediates for offset printing inks
    • Specialty paper dye enhancers
    • Colorant additives for polymer compounding
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    Certification & Compliance
    More Introduction

    N-Aminoethylpiperazine: A Cornerstone in Amine Chemistry

    Real-World Experience with N-Aminoethylpiperazine Production

    Decades of hands-on manufacturing have shaped how we view and handle N-Aminoethylpiperazine, commonly listed as AEP or N-AEP in technical circles. Our direct experience with the material, starting with its core chemistry and unfolding all the way to its role in global supply chains, brings a depth to this discussion found nowhere in reseller or distributorship reporting. We’ve watched AEP evolve from a niche intermediate into a key raw component relied on by industries that demand both reliability and versatility in their choice of amines.

    The model we manufacture sticks closely to industry expectations for pure, uncontaminated N-Aminoethylpiperazine. Our batches reach consistent assay measures, minimising the risk of variability. These results only come from refined process control at every stage, including precise distillation along with careful quality checks, not borrowed from someone else’s pipeline, but from our own hands and instruments.

    Aminoethylpiperazine: More Than Just a Piperazine Derivative

    N-Aminoethylpiperazine stands out for its unique molecular structure, where a piperazine ring carries an ethylene group capped by a terminal amino group. This difference in structure forms the basis for a host of reaction possibilities. We have produced hundreds of tons over the years, mostly for use in the formulation of epoxy curing agents, oilfield chemicals, polyurethane catalysts, and water treatment surfactants. Lab chemists familiar with straightforward ethyleneamines or simple piperazines quickly spot AEP’s extra functionality as both a secondary and a primary amine, which opens new doors for chemical bonding.

    Those in the coatings sector, for instance, look to N-Aminoethylpiperazine as a backbone for polyamide resins. The raw product flows off our distillation column as a colorless to slightly yellow liquid (depending on storage and age), with a distinct amine odor and a viscosity suitable for large-scale blending without further modification. The boiling point hovers at about 222°C at atmospheric pressure, while its amine equivalent weight sits at a value conducive to precise dosing in batch reactors; these are real numbers, confirmed batch after batch.

    Why Our AEP Differs from Basic Piperazines

    Engineers and formulators choosing between N-Aminoethylpiperazine and other aliphatic amines often want reliability in handling and the opportunity to leverage each amine’s distinct reaction pathways. Traditional piperazine lacks the extra aminoethyl group that makes AEP a better chain extender and crosslinking agent. In our controlled production runs, we consistently hit specifications that suit both bulk industrial requests and research applications demanding higher purity.

    Some buyers may compare AEP to diethylenetriamine (DETA) or triethylenetetramine (TETA). Both serve as multi-functional amines but behave differently in resin or surface-active syntheses. AEP’s blend of cyclic and linear segments grants better stability in some reactions, especially where temperature or pH changes could destabilize other amines. Through countless technical support calls and lab trials, we’ve seen customers describe how AEP grants a faster cure cycle in certain epoxies compared to other amine hardeners. Water treatment operators appreciate how its dual amine nature enables strong chelation, turning it into a robust complexing agent.

    Material Consistency and Specification Practices

    Direct manufacturing grants us unmatched control over final product quality. We don’t rely on open-market sourcing for intermediates; we run our own reactors under strict thermal and pressure conditions, then purify with multi-stage distillation and vacuum stripping. This sequence yields a final assay above 98 percent, typically closer to 99.5 percent, as measured by our in-house gas chromatography and titration. Water and chloride levels get measured batchwise, since small increases in these can affect performance in coatings or resins. Years of experience have taught us that no two reactors run exactly the same, so we’ve updated process sequencing and raw material supply grades to minimize yield losses and reduce off-grade formation.

    Consistency stretches beyond chemical purity. Every month brings a new set of supply challenges, from raw material cost shifts to changing demand in downstream applications. Only a real manufacturer can judge how to navigate these tides. We’ve weathered feedstock swings in both ethyleneamines and piperazine supply, using creative scheduling and diversified sourcing to shield customers from disruptions. Our own analytical teams verify every product lot, tying each shipment to a certified QC release record.

    Safety, Handling, and Environmental Stewardship

    N-Aminoethylpiperazine doesn’t present major hazards if treated with respect and standard good chemical practices, but every tank, drum, and tote that leaves our plant carries strict adherence to chemical hygiene out to each customer’s loading dock. We see firsthand how careless handling at the plant, warehouse, or user site leads to problems, especially because AEP’s strong alkalinity and moderate volatility can corrode unlined containers. Workers running the filling lines wear dedicated PPE, and each shift rotates through mandatory hazard review and handling refresher sessions. These small steps prevent shipment rejections and workplace injuries.

    On the environmental front, we keep AEP production emissions well below regulatory limits. Our vent scrubbing captures almost all stray amine vapors before they reach the atmosphere. Spent process liquids are neutralized in a dedicated treatment facility, sparing municipal systems from accidental discharge. Our waste numbers get shared with local authorities, and any process improvement that sheds a kilo of solvent or byproduct gets put in place, documented in our regular audit cycles.

    Applications Shaped by Long-Term Customer Engagement

    Aminoethylpiperazine gets used in products most people never see, even though many rely on it daily. Epoxy formulators value its rapid reactivity and lower color generation compared to heavier amine blends. We’ve worked in tandem with their technical teams, reformulating blends to accommodate ever-stricter VOC and amine emission regulations. Their feedback continues to push our quality control forward.

    Water treatment specialists count on AEP for ion exchange resins and chelating compounds. Our technical managers regularly assist their engineers in adjusting dose rates, precipitation points, and mixing regimes. In oilfield service applications, drilling fluid mix masters count on clean AEP to condition muds and serve as a corrosion inhibitor, both above ground and miles below the surface. Some companies use AEP to synthesize new polymer backbones, while others combine it with fatty acids to build surfactant blends that won’t break down in harsh environments.

    Nothing substitutes for face-to-face troubleshooting. We’ve sent teams to paint plants stuck with slow-curing batches, only to trace the issue to off-spec amine from another supplier. Once we reintroduced our AEP, targeted troubleshooting led to batches that met curing time windows, hardness specs, and color requirements. In textile treatment operations, using an AEP-based softener has helped maintain dye uptake and fabric hand in ways that other piperazines couldn’t match. Customer outcomes become a feedback loop, helping us refine future batches for both traditional and green chemistry processes.

    Why Formulators Choose Our AEP for Resin and Curing Chemistry

    Many users turn to N-Aminoethylpiperazine for its practical blend of structure and reactivity. Unlike resellers with little input into product origins, as manufacturers, we pay attention to how minor side impurities affect color, gel time, and shelf stability. Curing agents demand extremely tight control over amine balance. We’ve worked with some of the largest resin companies, tuning our AEP’s amine value so it won’t throw off formulation calculations.

    Epoxy applications especially benefit from the comparative purity and controlled moisture levels of our product. Excess water in the amine stream leads to hazing and loss of gloss in two-part epoxies. Close monitoring on our end means resin blenders can maintain a consistent look between batches and minimize end-user complaints. Because our AEP resists side reactions better than more branched alternatives, the resulting polymers form stronger, clearer films.

    Paint chemists need a chemical that balances resin extension and rapid crosslinking. They find AEP to be gentler on pigments and colorants, turning out coatings that hold hue longer and level more smoothly when sprayed or rolled. We work directly with their labs, sampling every outgoing drum to verify amine content instead of relying on spot checks or paper-only assurance. Feedback loops run back to plant engineers, so lessons learned in one market rapidly improve performance for all customers.

    Thinking Ahead: Sustainability and Raw Material Security

    Manufacturers face pressure to cut environmental impact while still meeting large-scale demand. Over the years, we’ve invested in process efficiency upgrades, including closed-loop solvent recycling and heat recovery from exothermic reaction steps. These efforts let us keep AEP pricing and quality stable during times of uncertainty. Alternative feedstock sourcing represents another area where direct manufacturer expertise matters: we stay in close touch with ethyleneamine and piperazine producers worldwide, tracking developments in both green and conventional synthesis routes.

    Sustainability efforts run beyond just numerical compliance. We embed continuous improvement into daily operations, leveraging data, staff feedback, and environmental audit results to spot inefficiencies before they grow. Our focus on minimizing batch waste, optimizing energy consumption, and updating tank cleaning regimens lowers the long-term footprint of every metric ton shipped. Customers working on “greener” blends know they can rely on us for support, not just with data but with custom blend development and supply chain review.

    Market Insights and Future Directions for N-Aminoethylpiperazine

    Demand surges happen fast, especially when shifts in regional manufacturing spur demand for specialty amines. From China’s new standards in epoxy flooring to North American water treatment upgrades, N-Aminoethylpiperazine shipments move quickly. We field inquiries daily from both established users and new entrants building capacity. Regional differences in regulatory and safety expectations mean the material specification—and our commitment to satisfied deliveries—never stays static. Comparing applications, AEP sees growing interest as a platform for specialty coatings and as a replacement for harsher, less environment-friendly amines.

    Formulators in specialty surfactants experiment with AEP for milder formulations without giving up performance. Polyurethane manufacturers look at it as a next-generation catalyst, providing faster reactivity in low-VOC and less hazardous blends. Each innovation starts with feedback cycles from users, not dictated by distant marketing campaigns but by conversations with plant operators and R&D chemists. By holding on to a direct line with the chemists who use our material, we spot application drift early, tune process settings, and help push both our product and our customer’s products forward.

    Closing the Knowledge Gap between Production and Application

    True manufacturer insight closes the knowledge gap between plant and end-use. Every tanker loaded from our facility brings the lessons learned from years refining both process and product. From basic resin chemists to oilfield teams troubleshooting a stubborn drilling fluid, these users depend on reliable, clean, and responsive amine chemistry that only a direct manufacturer can promise. We stand ready, not just to provide a high-quality N-Aminoethylpiperazine, but to back it up with the experience, responsiveness, and improvements that come from a long-term stake in the chemical’s future.

    Whether used in time-sensitive curing systems, cutting-edge surfactants, or critical water softening processes, our commitment extends beyond shipment. Every batch tested, every trend tracked, and every customer question answered helps move N-Aminoethylpiperazine from just another amine to a trusted cornerstone of modern chemical manufacturing.