Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Methyl Tert-Butyl Ketone

    • Product Name Methyl Tert-Butyl Ketone
    • Alias MTBK
    • Einecs 209-737-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    942822

    chemical_name Methyl Tert-Butyl Ketone
    chemical_formula C6H12O
    molecular_weight 100.16 g/mol
    appearance Colorless liquid
    odor Ketone-like odor
    boiling_point 94-95 °C
    melting_point -88 °C
    density 0.803 g/cm³ (at 20 °C)
    solubility_in_water Slightly soluble
    flash_point 10 °C (closed cup)
    refractive_index 1.393 (at 20 °C)
    vapor_pressure 61 mmHg (20 °C)

    As an accredited Methyl Tert-Butyl Ketone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Methyl Tert-Butyl Ketone is supplied in a 500 mL amber glass bottle with a secure screw cap and hazard labeling.
    Shipping **Methyl Tert-Butyl Ketone** should be shipped in tightly sealed, chemical-resistant containers, clearly labeled, and compliant with all relevant regulations. It must be transported as a flammable liquid, away from heat sources and incompatible substances. Appropriate hazard labels are required, and it should be handled by trained personnel wearing protective equipment.
    Storage Methyl Tert-Butyl Ketone should be stored in a cool, well-ventilated area away from heat, sparks, and open flames. Keep the container tightly closed and away from incompatible substances such as acids, oxidizers, and strong bases. Use approved, clearly labelled containers, and avoid exposure to direct sunlight or moisture. Implement proper grounding and bonding to prevent static discharge during handling.
    Application of Methyl Tert-Butyl Ketone

    Applications of Methyl Tert-Butyl Ketone in Industrial Manufacturing

    Methyl tert-butyl ketone (MTBK) is an essential intermediate and high-performance solvent used in a range of specialized chemical processing sectors. Our manufacturing expertise ensures consistent product quality and supply to support critical operations across various downstream industries.

    1. Pharmaceutical Intermediate Synthesis

    MTBK plays an important role in the pharmaceutical sector as a purification solvent and reaction medium for active pharmaceutical ingredient (API) synthesis. Its unique polarity and structural stability allow precise control over crystallization and extraction during multi-step organic syntheses. Pharmaceutical manufacturers value its low reactivity profile, which supports the integrity of sensitive reaction systems and allows compliance with stringent residue level specifications in API processes. Integration of MTBK is common for isolation of intermediates, where it improves product separation efficiency and enhances yield in batch and continuous reactor systems.

    Industry compliance standards

    • Current Good Manufacturing Practices (cGMP, ICH Q7)
    • USP/NF and European Pharmacopoeia residual solvent limits
    • FDA 21 CFR Part 211
    • ICH Q3C (R8) Guidelines for residual solvents

    Typical usage ratio

    • Solvent to substrate ratios: 2:1 to 5:1 w/w, optimized according to reactant solubility and downstream chromatography requirements
    • Adjusted based on solvent recovery strategy and process scale

    Downstream process integration

    • Charged to reaction vessel during intermediate synthesis or crystallization step
    • Used in post-reaction extraction and washing phases
    • Subjected to solvent recovery and distillation loops to reduce process costs

    Final product types

    • Active pharmaceutical ingredients (APIs)
    • Small-molecule drug intermediates
    • High-purity pharmaceutical intermediates

    2. Agrochemical Formulations

    In agrochemical manufacturing, MTBK serves as a selective solvent for the formulation of herbicides and pesticides, enabling dissolution of specific active compounds that require medium polarity. The material’s low water miscibility allows agrochemical formulators to control emulsion stability in suspension concentrate and emulsifiable concentrate production lines. This enhances dispersion quality and shelf-life of the formulated agrochemical products, maximizing field effectiveness. Regulatory requirements drive analytical monitoring to manage residual levels and ensure compliance, especially for export markets.

    Industry compliance standards

    • FAO/WHO Specifications for Pesticides
    • REACH Regulation (EC) No 1907/2006
    • China National Standards for Pesticides (GB/T 1604-2014)
    • EPA requirements for inert ingredients

    Typical usage ratio

    • Solvent concentration: 10–30% w/w depending on formulation type, active ingredient solubility, and desired viscosity characteristics
    • May be further diluted or combined with co-solvents based on sprayable end-use requirements

    Downstream process integration

    • Mixing in high-shear formulation equipment for emulsifiable concentrates
    • Added during pre-milling or final blending to achieve target homogeneity
    • Subjected to final QC for clarity and emulsification properties before packaging

    Final product types

    • Emulsifiable concentrate herbicides
    • Suspension concentrate insecticides
    • Pre-emergent fungicide formulations
    • Pesticide adjuvants

    3. Synthetic Resin Production

    MTBK is incorporated as a process solvent and phase modifier in the synthesis of certain acrylic, polyester, and polyurethane resins. It assists resin manufacturers by enabling better dissolution of monomers and fine-tuning the polymerization kinetics for molecular weight control. Due to its moderate boiling point and low tendency for side reactions, MTBK is selected for processes needing precise temperature management and uniform chain extension during bulk, solution, or suspension polymerizations. This improves product performance consistency for downstream applications in coatings and adhesives.

    Industry compliance standards

    • ISO 14001 (Environmental Management for chemical industries)
    • REACH Annex II (Safety data sheet requirements)
    • Japanese Chemical Substances Control Law
    • EU Directive 2004/42/EC (VOC contents in coatings/adhesives)

    Typical usage ratio

    • Solvent volumes: 8–25% of total monomer feed for solution and suspension polymerizations
    • Adjusted according to target resin molecular weight and viscosity specifications

    Downstream process integration

    • Blended with feed monomers prior to initiation of polymerization batch
    • Acts as diluent during resin kettle operations for controlled exothermic reactions
    • Removed by vacuum stripping or flash evaporation before resin finishing

    Final product types

    • Acrylic and polyester resins for industrial coatings
    • Polyurethane prepolymers for adhesives
    • Modified alkyd resins
    • Specialty thermoset intermediates

    4. Electronics Cleaning and Precision Degreasing

    The electronics manufacturing sector utilizes MTBK for cleaning, degreasing, and defluxing critical components, including printed circuit boards (PCBs) and precision optical parts. Its effective solvency toward oils, silicones, and flux residues supports high purity requirements in semiconductor and optoelectronic assembly environments. Consistent raw material quality and controlled volatility are essential to avoid micro-contamination or ionic residues that could compromise component reliability, requiring strict process validation and traceability.

    Industry compliance standards

    • ISO 14644 (Cleanroom and controlled environment protocols)
    • J-STD-001 (IPC Standard for soldered electronic assemblies)
    • RoHS 2011/65/EU (Restriction of Hazardous Substances Directive)
    • JEDEC JESD625 (Requirements for handling electrostatic-discharge sensitive devices)

    Typical usage ratio

    • Applied via immersion or ultrasonic cleaning at 100–400 g/L, based on degree of soiling and component geometry
    • Adjusted depending on bath renewal rates and throughput

    Downstream process integration

    • Direct addition to automated cleaning or wipe-down stations
    • Recirculated in closed-loop systems with inline purity monitoring
    • Integrated with rinse and drying steps to minimize solvent retention

    Final product types

    • Cleaned semiconductor wafers
    • Ready-to-assemble PCB assemblies
    • Optical lenses and microelectronic modules
    • High-purity packaging substrates
    Free Quote

    Competitive Methyl Tert-Butyl Ketone prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

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    Certification & Compliance
    More Introduction

    Methyl Tert-Butyl Ketone: Our Hands-On View from the Production Line

    Our Real Work with Methyl Tert-Butyl Ketone

    Walk through our plant, and you’ll find Methyl Tert-Butyl Ketone — known among our staff and regular clients as MTBK — in continuous production. We’ve spent decades refining the manufacturing process so that the final product leaves no question marks about consistency, performance, or safety. The model produced here carries a purity of 99.9%, achieved by tightly monitored distillation and rigorous in-line controls. Continual real-time monitoring, not just batch-end testing, keeps every drum up to the promise we stamp on it.

    Practical Uses Born from Manufacturing Experience

    Methyl Tert-Butyl Ketone’s name doesn’t often leave mouths around the dinner table, but the industries that depend on it feel its value every day. Most demand comes from those needing a strong, reliable solvent, particularly in paints and coatings. Whenever a paint shop promises fast drying without compromise, there’s a good chance our ketone plays a role. In adhesives, its low water content and powerful solvency create bonds that last. Electronics manufacturers favor it for cleaning circuit boards due to low peroxide formation and exceptional drying speed. Our engineers have worked side-by-side with R&D teams from each of these industries, fine-tuning purity and water content to levels that guarantee no surprises out on the customer’s line.

    How MTBK Stands Apart

    Manufacturers often ask why not stick with standards like methyl ethyl ketone or acetone. Experience at scale taught us that MTBK kicks up performance where evaporation rate, boiling point, and solvent strength align just right. MTBK features a higher boiling point, falling in the 102 to 104°C range, so it sticks around longer where slower evaporation matters, like in specialty lacquers or inks. Chemists on our team point out how the structure — with its tert-butyl group — gives it different solubility ratios. In heavy-duty degreasing, for example, we’ve seen it break down stubborn residues that leave others behind.

    Choosing Specs That Match Application

    Our own daily production tests illustrate the importance of tight specifications — not all MTBK grades suit every job. The high-purity 99.9% material takes priority for electronics and pharmaceuticals, where even minor impurities risk damaging circuits or contaminating sensitive intermediates. In paints, where the volume runs higher and cost control matters, we switch to variants with slightly wider impurity tolerance (still below 0.1%). Water content always stays below 200 mg/kg for strict industrial users and below 100 mg/kg for top-grade customers. We don’t rely on theoretical standards; our QC labs draw random samples from every batch to confirm these targets, and we use Karl Fischer titration and advanced gas chromatography, methods we trust for accuracy.

    Working Directly with MTBK in the Field

    Crews at customer sites give us real-world stories to go along with plant data. In adhesive lines, workers noticed fewer flow disruptions after switching from traditional MEK to MTBK — not a claim on a brochure, just real-time feedback. Textile coaters tell us about sharper lines in printing, which only came with the MTBK batch they picked up during peak season. We hear from cleaning contractors for high-precision parts that residue dries fast, but not too fast to leave streaks, a balance we built into the product by adjusting the reflux conditions in our columns. Our plant operators use these stories to tune their parameters, aiming for quality that matches what workers out in the field really need.

    Meeting Tougher Regulatory Demands Head-On

    MTBK production in our plant means navigating a maze of air permits, effluent controls, and workplace exposure regulations. We learned from the 2020 updates to VOC laws — reducing emissions through a new condensation recovery system installed on the main vent lines. Customers routinely request details about our compliance with European REACH or California air toxics rules. We supply third-party audit data, plus our own certifications, to assure them the product fits evolving legal and workplace demands. By controlling the entire manufacturing chain, from raw material purchase to final shipment, we guarantee traceability and peace of mind for everyone down the supply chain.

    Flexibility of Form and Packaging Developed on Request

    Our standard models focus on bulk liquid, packaged in 200-liter drums, but the order desk receives requests for totes, pails, or even smaller lab packs. Several customers in specialty labs asked us to supply ultra-dry MTBK in sealed containers purged with nitrogen to avoid water pickup — a line we developed after some heart-to-heart talks with field chemists. The shelf stability matters most where strict analytical performance counts. We went back to the drawing board in our packaging unit and switched from basic drums to composite-lined containers for customers with extra-long shelf requirements. Working on these details makes the product function smoothly where it lands, not just where it’s filled.

    Comparison to Industry Staples: Experience Makes the Real Difference

    Many buyers come in expecting to see the same advantages as MEK — after all, they share some functional similarities on paper. Experience, though, shows clear differences. Compared to methyl ethyl ketone, MTBK carries extra bulk from the tert-butyl group, which slows evaporation and increases resistance to hydrolysis. We’ve seen this matter in cement formulations, where longer working times can mean fewer wasted batches. Compared to acetone, MTBK stands out with higher selectivity in dissolving both polar and non-polar resins. Tests in our application lab verify that pigment dispersion stays more even over time, which is crucial for automotive coatings.

    Handling and Safety from the Manufacturer’s Viewpoint

    From inside the plant, regular safety walks remind us of the flammability and volatility risks. MTBK holds a flash point above 20°C, demanding strict handling procedures in storage and transfer. Our teams rely on explosion-proof pumps and vapor recovery systems, putting workplace safety before delivery speed. Many downstream users ask about these measures, especially after high-profile incidents in chemical plants worldwide. From our side, we remind partners that MTBK, with its lower toxicity relative to some classic ketone solvents, helps reduce exposure risk — though don’t mistake this for a green pass; we train staff for immediate spill control and fire prevention. Our own accident records reflect the seriousness with which we approach every shipment.

    Real-World Challenges: Raw Materials, Markets, and Innovation

    MTBK production draws heavily on reliable access to isobutene and methyl ethyl ketone feedstocks. Sudden swings in the upstream petrochemical market force us to source smarter and invest in storage flexibility. In 2022, a global isobutene shortage meant we had to fend off expensive offers from many trading houses. Instead, our procurement team leaned on longstanding partnerships with refineries willing to guarantee quality specs even through tight times. This commitment means customers never see a drop in consistency, even during market disruptions that leave some without raw material.

    Innovation on the plant floor continues as we look for ways to trim energy use and cut emissions. Switching from older column trays to high-efficiency packing reduced reboiler fuel consumption by over 14% through the past year, a number confirmed by our own utility meters. Each process tweak gets evaluated not just for cost savings, but for how it might alter impurity profiles — our technical staff oversee every trial, and nothing hits the shipping dock until it passes repeated validation.

    Supporting Customer Formulations by Listening, Not Just Supplying

    Decades in this business taught us that solvent supply succeeds by getting in sync with application chemists. Paint factories want solvents that don’t case-harden finishes or clog lines; ink producers need slow evaporation to avoid ghosting. We spend time on site, not just delivering product but collecting small-scale test results. That’s how we discovered that some ink makers struggled with pigment settling using MEK, and only switched to MTBK after sharing their lab data. Feedback loops drive our process changes; if a batch leaves streaks, it gets investigated by both plant QA and the application team until a fix gets found on both ends.

    Environmental Responsibility and MTBK

    The chemical business answers more environmental questions than ever. Through every stage, we focus on MTBK recovery — vent condensers, solvent reclaim systems, and energy-efficient operations serve both business needs and global demands for greener processes. Customers often ask about recycling programs or treated waste streams. Our plant runs its own on-site solvent recovery setup, collecting off-spec or surplus MTBK and returning it to the distillation loop. This closed-loop design trims both emissions and raw material demand, pushing our environmental performance far beyond basic compliance.

    Hazardous waste remains tightly controlled — we document every drum and sample for auditors, with transparent reporting to regulatory agencies. No quick fixes or greenwashing can replace true reductions, and our team tracks every improvement with hard metrics. Industry partners share best practices, helping us push performance and keep the product as clean as technology allows.

    Facilitating Smooth Integration for Downstream Users

    Each MTBK shipment covers more than a drum with a label. We help customers with handling guides based on our plant’s own safety procedures. Training sets the tone — how to avoid static discharge, the right venting, protective gear for high-exposure jobs. Questions about shelf life or compatibility with storage tanks reach us almost daily, and we respond with details drawn from our everyday experience. Larger users sometimes consult us for advice fitting MTBK into new formulations; these joint projects often start with us sending out test batches, then running back iterative improvements based on their pilot line feedback.

    We answer technical questions about specific resin compatibility, evaporation curves at different ambient temperatures, and solvent blends. Our field team works with R&D groups, not just purchasing offices — a two-way street where both sides learn and update processes for what actually works, not just what’s found in a manual.

    Anticipating the Future Needs of the Industry

    MTBK demand seems likely to grow with the rise of specialty coatings, electronics, and greener adhesive solutions. Alongside, regulatory pressure will only increase. Our investment in real-time emissions monitoring, worker safety programs, and higher-purity product lines positions us to handle these twin challenges. We’re constantly exploring new catalyst systems to boost yield and cut side-reactions, with lab teams dedicated to predictive modeling and small-scale pilot synthesis. Only by staying ahead technically and through customer input can we keep making MTBK that serves modern manufacturing and society’s growing demands for clean, safe, and effective solutions.

    Conclusion: The Value of Direct Manufacturing Experience

    Across decades, we’ve learned that making MTBK is a craft — blending technical control, flexible operations, and a willingness to adapt based on what real processors need. No marketing pitch substitutes for hands-on trials, direct supply chain accountability, and feedback that goes straight back to the factory floor. With each batch, we serve partners who count on MTBK to deliver performance, reliability, and compliance — not as a distant supplier, but as the manufacturer willing to put our experience to work.