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Methyl Isopropenyl Ketone [Stabilized]

    • Product Name Methyl Isopropenyl Ketone [Stabilized]
    • Alias Methyl Vinyl Ketone
    • Einecs 202-496-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
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    Specifications

    HS Code

    673695

    Chemical Name Methyl Isopropenyl Ketone
    Synonyms 3-Buten-2-one, 3-methyl-; MIPK
    CAS Number 563-80-4
    Molecular Formula C5H8O
    Molecular Weight 84.12 g/mol
    Appearance Colorless liquid
    Odor Sharp, acetone-like
    Boiling Point 92-94°C
    Flash Point 1°C (closed cup)
    Density 0.852 g/cm3 at 20°C
    Solubility Miscible with water, alcohol, ether
    Stabilizer Typically contains 100 ppm hydroquinone
    Vapor Pressure 66 mmHg at 20°C
    Refractive Index 1.418-1.420 at 20°C
    Melting Point -99°C

    As an accredited Methyl Isopropenyl Ketone [Stabilized] factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Methyl Isopropenyl Ketone [Stabilized], 500 mL, supplied in an amber glass bottle with a secure screw cap for safe storage.
    Shipping Methyl Isopropenyl Ketone [Stabilized] should be shipped in tightly sealed, properly labeled containers, kept cool, and away from sources of ignition. It is classified as a flammable liquid (UN No. 2397, Hazard Class 3), and must be transported in compliance with relevant regulations, using appropriate protective measures for handling and spill prevention.
    Storage Methyl Isopropenyl Ketone [Stabilized] should be stored in a cool, well-ventilated area, away from direct sunlight, heat, and ignition sources. Keep the container tightly closed and isolated from oxidizing agents, acids, and bases. Use containers made of compatible materials and ensure proper grounding and bonding to prevent static discharge. Avoid storage near food or combustible materials.
    Application of Methyl Isopropenyl Ketone [Stabilized]

    Applications of Methyl Isopropenyl Ketone [Stabilized] in Industrial Manufacturing

    As a primary manufacturer, we maintain supply security, verified traceability, and technical process support for customers using Methyl Isopropenyl Ketone [Stabilized] in industrial settings. We ensure supply batches adhere to end-market protocols, and we collaborate with downstream producers to optimize application performance within specialized sectors. Below, we outline major application routes with core compliance, usage, processing, and product details.

    1. Acrylic Resin Synthesis for Automotive and Industrial Coatings

    Within acrylic resin manufacturing, formulators incorporate our stabilized material as a reactive ketonic monomer to tailor glass transition temperatures, control molecular weight, and enhance co-monomer reactivity during emulsion and solution polymerization. Its defined reactivity profile improves the resulting resin’s balance of hardness, flexibility, and weatherability, directly impacting final coating performance for demanding exterior and interior surfaces.

    Industry compliance standards

    • ISO 9001:2015 (Quality Management Systems for chemical manufacturing)
    • ISO 11890-2 (Coatings and varnishes - Determination of volatile organic compound content)
    • REACH Regulation (EC) No 1907/2006 (Registration, Evaluation, Authorisation and Restriction of Chemicals – Europe)
    • GB 18582-2020 (China VOC Limits for Architectural Coatings)

    Typical usage ratio

    • 3–8% w/w, adjusted by polymerization method and functional requirements, often increased for specialty high-performance coatings demanding lower VOCs and enhanced weather resistance.

    Downstream process integration

    • Added directly as a monomer component during initial batch charging and pre-polymerization, with stabilized grade preserving kettle safety and consistent monomer activity.

    Final product types

    • OEM automotive coatings
    • Industrial protective paints (including heavy machinery and marine)
    • Plastic and metal substrate lacquers
    • Decorative architectural finishes

    2. Agrochemical Synthesis: Selective Herbicide Building Blocks

    Methyl Isopropenyl Ketone [Stabilized] serves as an essential intermediate in multi-step syntheses within the pesticide sector, particularly in the formation of heterocyclic moieties for selective herbicides. Its use streamlines carbon–carbon coupling and controlled alkylation steps, minimizing byproduct formation. End-users depend on our purity control and stabilized monomer protocols to reduce process hazards and ensure robust scalability from kilo-lab to full-scale batch reactors.

    Industry compliance standards

    • FAO/WHO Specification Guidelines for Pesticides
    • ISO 9001:2015
    • Production Licensing for Pesticide Intermediate Manufacturers (e.g., China Decree 677)
    • EU Regulation (EC) No 1107/2009 (Plant Protection Products Authorization)

    Typical usage ratio

    • 0.5–1.2 molar equivalents in condensation or alkylation stages, calculated relative to base heterocycle; adjusted as per reaction efficiency and crop-selectivity target molecules.

    Downstream process integration

    • Introduced during controlled feed to catalytic reactors or stepwise condensation, with stabilization ensuring safe handling under ambient and mildly elevated temperatures.

    Final product types

    • Pyridine- or pyrazole-based herbicide active ingredients (e.g., for rice, maize, wheat fields)
    • Post-emergent weed control actives

    3. Photoinitiator Intermediate Production for UV-Curable Inks

    In specialty chemical operations, manufacturers employ our stabilized material as a critical intermediate when synthesizing high-efficiency photoinitiators, necessary for UV-curable ink and coating systems. This application leverages its reactivity for the formation of benzophenone- or acetophenone-class photoinitiators, ensuring controlled polymer crosslinking and rapid surface cure. Downstream customers benefit from strict quality controls that support consistent absorption spectra and minimized background yellowing.

    Industry compliance standards

    • ISO 2846-1 (Graphic technology — Color and transparency for offset inks)
    • EuPIA Exclusion Policy for Printing Inks and Related Products
    • REACH SVHC Directive (Candidate List Substances of Very High Concern)
    • FDA 21 CFR 175.300 (Indirect Food Additives: Paper and Paperboard Components, for food packaging inks)

    Typical usage ratio

    • 10–20% by mole in photoinitiator intermediate syntheses, adjusted based on desired photosensitivity, pigment interaction, and ink film thickness requirements.

    Downstream process integration

    • Reacted during intermediate formation in closed reactors, usually under inert atmosphere, followed by downstream purification for high chromatic purity.

    Final product types

    • UV curing photoinitiators for flexographic, offset, and digital printing
    • UV-curable overprint varnishes and adhesives
    • High-speed industrial packaging inks

    4. Organic Synthesis Intermediate in Pharmaceutical Fine Chemicals

    Pharmaceutical and fine chemical synthesis routes require high-purity, process-stabilized raw materials for the preparation of specialty intermediates, including those found in analgesics, anti-inflammatories, and other active compounds. Methyl Isopropenyl Ketone [Stabilized] affords a controlled carbonyl building block for Grignard and Knoevenagel condensation reactions, facilitating stepwise chain elongations essential in complex molecule assembly. We advise our pharma clients on appropriate batch records and GMP-compatible stabilization controls for regulated markets.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • Ph. Eur., USP, JP (Pharmacopoeial monographs as applicable to intermediates)
    • ISO 9001:2015
    • 21 CFR Part 210/211 (FDA cGMP for Finished Pharmaceuticals; relevant for intermediates entering clinical pipelines)

    Typical usage ratio

    • 1.0–1.3 equivalents in nucleophilic acyl substitution or condensation steps; modified upon purification needs and target intermediate yield.

    Downstream process integration

    • Charged under inert or low-oxygen conditions, following initial reactant preparation and prior to work-up, to minimize peroxide formation and side reactions.

    Final product types

    • Fine chemical intermediates for NSAID APIs
    • Specialty building blocks for anti-infectives or metabolic drugs
    • Screening library compounds in preclinical research

    5. Chemical Crosslinking Agent for Specialty Elastomers

    Rubber product formulators select Methyl Isopropenyl Ketone [Stabilized] as a functional crosslinking modifier in specialty elastomeric compounds, where its vinyl-functional group enables selective grafting and thermo-crosslinking. This enhances modulus and chemical resistance for technical rubber articles. Controlled addition improves reproducibility and mechanical stability, supporting the production of critical sealing, insulation, and vibration-dampening products for automotive and industrial sectors.

    Industry compliance standards

    • ISO 9001:2015
    • ISO 37 (Rubber, vulcanized or thermoplastic – Tensile stress-strain properties)
    • RoHS Directive 2011/65/EU (Restriction of Hazardous Substances)
    • EN 681-1 (Elastomeric seals – Materials requirements for pipe systems)

    Typical usage ratio

    • 1–4 parts per hundred rubber (phr) in masterbatch formulation, with recipe adjustments made for desired crosslink density and end-use mechanical performance.

    Downstream process integration

    • Metered during compounding stage upstream of vulcanization, either via internal mixer or continuous kneader, ensuring uniform matrix distribution before crosslink initiation.

    Final product types

    • Automotive engine gaskets
    • High-performance vibration dampers
    • Pipe system and infrastructure elastomeric seals
    Free Quote

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    Certification & Compliance
    More Introduction

    Methyl Isopropenyl Ketone [Stabilized]: A Closer Look from the Manufacturer

    Working Hands-On With Methyl Isopropenyl Ketone [Stabilized]

    After many years at the heart of chemical synthesis, our team has developed a steady comfort with the quirks and advantages that come with using Methyl Isopropenyl Ketone [Stabilized]. This compound, also referred to as 3-methyl-3-buten-2-one, continues to earn its place as a staple in our production routines, and it’s the kind of solvent that shows its personality right at the interfaces—between monomers, in acrylics, and across polymerization tasks. We spend our days in coats and gloves, making adjustments batch after batch, so it feels natural to talk about what truly matters out on the plant floor rather than keep things locked away in specification sheets.

    No Substitute for Consistency and Safety

    Not every ketone takes kindly to heat or exposure. This one has a sharp odor and acts as a strong solvent, mixing with water only to a limited extent, but freely blending with other organic solvents. The stabilized grade—what we insist on shipping and using—carries an extra layer of reliability. Without adequate stabilization, uncontrolled polymerization kicks in before you reach the final line in your batch log, which can destabilize whole production shifts. Our stabilized variant comes ready with polymerization inhibitors; in our operations, we work with methyl isopropenyl ketone containing 90-99% purity and the right threshold of inhibitor additives, so it never surprises anyone on the team. Factories see real cost advantages by eliminating down-time due to runaway exotherms or sticky residue in pipes.

    Where Methyl Isopropenyl Ketone [Stabilized] Delivers the Most

    Chemistry is rarely about a single molecule; it’s about transforming it. Our engineers turn to methyl isopropenyl ketone when the desired output needs a strong, reactive carbonyl group in a liquid that stays manageable. In the world of fine chemicals, this ketone steps smoothly into synthesis of vitamin intermediates, headache powders, and even photo-initiators for UV-cured coatings. In acrylic resins, it shines as a copolymerization monomer. Our clients in the coatings and adhesives sectors often put it to work modifying polymer chain length or boosting solvent evaporation rates. The feedback we’ve received from process leads is simple—they want a ketone that’s quick to integrate, not fussy, and nearly impossible to “overreact.”

    The stabilized grade makes handling worry-free. Standard grades of this material, when left unstabilized, begin self-polymerizing at ambient temperatures. Vents clog, tanks heat up, and the end-user faces material loss—or worse, a plant shutdown. Our choice to supply only the stabilized version traces directly to these issues, not marketing trends.

    Following the Details: Purity and Inhibitors

    Ongoing experience has proved that trace impurities do more harm than good. An impure batch of methyl isopropenyl ketone throws off reaction monitoring, especially during sensitive steps like Grignard additions or Friedel–Crafts acylations. Some clients have shared stories about variant results in batch heterogeneity when sourcing from general traders. By keeping synthesis, distillation, and packaging under the same roof, our team controls purity right from the raw feedstock through finished product. The purity window of our production, targeting 98.5% or higher by GC assay, enables exacting users to plan their batch sequences without worrying about build-ups or ghost peaks in their QA chromatograms.

    We employ standard inhibitors—often hydroquinone monomethyl ether (MEHQ) or sometimes phenothiazine—to keep the product shelf-stable for both shipment and in-plant storage. Our colleagues in QA keep tight logs showing that even with extended storage, inhibitor levels don’t tail off unpredictably. These scavengers work because they target early radicals, nipping unwanted chain reactions right from the start without interfering in planned synthesis.

    What Sets Our Process Apart

    It’s easy to overlook the difference between a chemical made at scale and one batch-cooked for demonstration. To us, each reaction vessel cycle serves as a learning moment. Purification through careful distillation and in-line nitrogen blanketing prevents fraction cross-contamination and keeps oxidizers at bay. Tanks and pipelines cleaned on a strict schedule show dramatically fewer incidents of residue buildup—a fact our plant teams attribute to limiting the number of suppliers for key solvents, including methyl isopropenyl ketone. Unlike some operators, we tightly control delays between synthesis and inhibitor addition, keeping our solvent ‘fresh’ for significantly longer in drum storage.

    While the basic model of methyl isopropenyl ketone feels simple on a flow chart, there’s nuance at every step. Every batch gets tested for color (APHA), water content (Karl Fischer), density, and acid value. Something as subtle as a too-dark APHA can cause troubles in optical fiber coatings or transparent lacquers.

    Production and Handling: What We’ve Learned

    Storage tanks vented with dry nitrogen and finished drums packed right after inhibitor dosing define our operational standard. Long ago we discovered the consequences of open-head drums and ordinary air blanks, with oxygen creeping in and altering the inhibitor efficiency. Now, every bulk shipment comes with a certificate of analysis referencing timed GC and inhibitor percentage checks, and our customers have told us they see this reflected in batch-to-batch uniformity.

    Weighing out methyl isopropenyl ketone requires thorough ventilation and solvent-resistant gloves, as skin contact leads to irritation and nuisance odors linger in poorly vented corners. We insist on vapor detection alarms on loading docks. In our hands, even the tiniest leaks show up quickly, and plant workers trust the audit history because we close every root-cause loop at the site of even the smallest mishap.

    Differences That Matter: Comparing To Other Ketones and Analogues

    A lot of folks in formulation circles ask how methyl isopropenyl ketone differs from similar molecules. For one, the isopropenyl group lends it faster reactivity than methyl ethyl ketone or methyl isobutyl ketone, particularly in acrylate co-monomer tasks. Its lower boiling point means quicker drying on application, but it does build up vapor pressure noticeably, so exhaust air handling needs closer attention. Compared to methyl vinyl ketone, the stabilized grade cuts back dramatically on storage instability and the potential for runaway polymerization.

    For those who have dealt with acetone or butanone in similar applications, switching over to methyl isopropenyl ketone brings improved control in peroxide-initiated reactions, tighter handling of sidechain modifications, and a cleaner profile for downstream purification. The difference really comes through on the plant line; waste streams show fewer residual odors, and changeovers run faster because less residue clings to tanks. Many resin operators, facing stricter VOC caps, turn to this compound when acetone’s evaporation rate proves excessive.

    Usage in Real-World Applications

    Batch operators in our plant have watched this solvent anchor not just the reaction kettles in our syntheses, but also the daily production in customer factories. In coatings, it imparts quick set and rapid cure in even thick formulations, which means faster turnaround on finished goods. Adhesive formulators keep telling us about improved peel strength—attributed to the sharp solvency profile that methyl isopropenyl ketone brings to the resin blend.

    We’ve shipped drums across the world to users making specialty lenses, composite panels, and surface treatment chemicals. A major resin plant using our methyl isopropenyl ketone for their binder system called out how the stabilized nature reduced downtime linked to unexpected fouling of their feed lines. In small-scale pharmaceutical synthesis, chemists gain batch reliability and a margin of safety thanks to the predictable inhibitor action.

    Quality Control Meets Experience

    Building confidence in a chemical takes more than a data sheet; it's the dozens of decisions made in the production hall, the feel of the material when poured, and the feedback from operators who know what a “good” batch smells like. Each day, our QC team logs every batch, comparing titration results and monitoring inhibitor content as the weeks roll by. Producers who rely on our shipments come back to us not just for purity, but for the long-term consistency created by experience and in-house process controls.

    Contamination never gets a free pass. Our own samples get reserved and tracked, and any deviation above threshold gets traced back to a root cause. This work feeds directly into better handling manuals for our partners and internal staff, closing the loop with every finished batch.

    The Real-World Risks and How We Face Them

    Anyone who’s handled large tanks of methyl isopropenyl ketone understands the risks of fire, fume, and overexposure. To minimize incidents, we train each shipment handler in spill containment, drum grounding, and fast-response patching. Evaporation loss gets locked down with vapor tight seals. We’ve worked through process audits where regulators want step-by-step validation—from the first feedstock measure to the last drum closure. No magic, just discipline and engineering controls.

    Between regulatory visits, our team doesn’t let safety culture slide. Knowing that a runaway polymerization event can ratchet the temperature up within minutes keeps everyone vigilant—the difference comes from the stabilized product always arriving at the right purity and inhibitor level.

    What End Users Look For—and What We’ve Learned to Provide

    Operators in resin plants, adhesive production, and pharmaceutical synthesis want more than high assay numbers. They demand transparency on each drum—where it started, when it was filled, how it was stored, and exactly what inhibitors and levels it carries. That’s why we integrate barcoding and batch analytics into each unit shipped from our facilities.

    Each application has unique requirements for solvent evaporation, reactivity, and compatibility with other components in the formulation chain. Methyl isopropenyl ketone, in its stabilized form from our lines, gives that measurable performance jump—whether that means improved cure time in a UV coating or reduced side reactions in an active pharmaceutical ingredient intermediate.

    Reducing Environmental and Process Impact

    Waste management isn’t just a headline here; it’s built into every tanker and drum we fill. By sending out methyl isopropenyl ketone stabilized against premature polymerization, we keep downstream waste low since unused or returned solvent remains viable for reworking. Our own plant tracks VOCs and solvent losses, reporting back to the engineering team for constant process improvements.

    Some customers have expressed concern about what happens at end of use. By providing waste handling guides, spill response kits, and technical seminars along with our shipments, we make sure operators and environmental managers have needed tools and up-to-date information for downstream treatment and safe disposal.

    The Supply Chain and What We’ve Tackled

    Supply chain delays or mishandling threaten the quality and stability of this product more severely than many other ketones. Our logistics colleagues ensure drum turnover times remain low, transfer lines never sit idle more than necessary, and every container travels under the right climate protocols. We have adopted serialization so each user can trace their shipment back to its exact run.

    By using one dedicated stabilization and packaging line, we avoid the cross-contamination that can occur in mixed-use plants. Our dock staff have real-time monitoring for inhibitor levels, scan shipments out, and rerun drums that don’t meet our standards.

    Advancing With Industry Demands

    Emerging industries—from energy storage films to high-performance elastomers—have pushed us to evaluate how methyl isopropenyl ketone stabilized can meet tougher requirements. In joint development projects, we’ve customized purity specs and inhibitor blends at the bench level, then scaled up while guarding against instability. Each new demand brings operational learning that echoes through future shipments.

    We see partners from Asia, Europe, and the Americas tuning their feedback loops ever tighter with us, driving collaborative trials and on-line process analytics that reflect the evolving role of methyl isopropenyl ketone in modern synthesis.

    Final Thoughts: The Manufacturer’s Assurance

    Having spent years making, packaging, and shipping this solvent, the team here learned that it is the layered expertise—raw material control, reaction discipline, purification consistency, and the humble daily routines—that build real trust. Every client batch represents hundreds of small decisions made by operators who understand how subtle shifts can become plant-wide events. Delivering methyl isopropenyl ketone stabilized with the right specs means more than meeting a target number. It’s a pledge to every user down the chain that they’re working with a product made with intent and guarded by practical, hard-won know-how.

    Those new to this ketone learn quickly that stabilization is the difference between a batch worth bottling and a process stoppage. Our resolve remains steady: supply with transparency, traceability, and a commitment to safe, consistent, and responsible chemical manufacturing.