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Methyl 2-Butenoate

    • Product Name Methyl 2-Butenoate
    • Alias Methyl crotonate
    • Einecs 204-644-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    531326

    chemical_name Methyl 2-Butenoate
    molecular_formula C5H8O2
    molar_mass 100.12 g/mol
    cas_number 623-42-7
    appearance Colorless liquid
    boiling_point 110-112 °C
    density 0.928 g/mL at 25 °C
    refractive_index 1.419-1.421
    flash_point 17 °C (closed cup)
    solubility_in_water Slightly soluble

    As an accredited Methyl 2-Butenoate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Methyl 2-Butenoate is packaged in a 500 mL amber glass bottle with a secure screw cap and hazard labeling.
    Shipping Methyl 2-butenoate should be shipped in tightly sealed containers, clearly labeled, and protected from heat, sparks, and open flames. It is transported as a flammable liquid under standard chemical shipping regulations. Ensure compliance with local, national, and international transport guidelines, including proper documentation and hazardous materials handling procedures.
    Storage Methyl 2-butenoate should be stored in a cool, dry, and well-ventilated area, away from heat sources, direct sunlight, and incompatible materials such as strong oxidizers and acids. Keep the container tightly closed and properly labeled. Store in a flammable liquids cabinet if available, and ensure all local regulations for storage and handling of flammable chemicals are followed.
    Application of Methyl 2-Butenoate

    Applications of Methyl 2-Butenoate in Industrial Manufacturing

    As a direct manufacturer, we supply high-purity methyl 2-butenoate for established verticals with proven industrial-scale use. Below, we detail authentic downstream sectors and specialized process integration, referencing strict industry benchmarks for compliance, dosing, and finished product categories.

    1. Agrochemical Synthesis Intermediates

    Methyl 2-butenoate is essential in the fine chemicals synthesis chain for select herbicides and plant growth regulators. It serves as a key Michael acceptor and enables ester-functionalization in multi-step routes for the manufacturing of active agrochemical compounds with defined safety and quality requirements at scale.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for chemical safety
    • FAO/WHO Specifications for Crop Protection Products
    • ISO 9001:2015-certified QC for traceability
    • Local Environmental Emission Standards for process solvents (e.g., China GB 8978-1996, US EPA Clean Air Act Title V permits)

    Typical usage ratio

    • Employed at 10–30 mol% in the total synthesis, with adjustments depending on the target molecule’s reactivity; precise ratio based on stoichiometry of downstream condensation or cyclization reactions.

    Downstream process integration

    • Charged into primary or secondary reaction vessels as a Michael acceptor during intermediate synthesis, before isolation and purification of the downstream product.

    Final product types

    • Herbicide technical concentrates
    • Plant growth regulator intermediates
    • Custom agrochemical actives

    2. Pharmaceutical Fine Chemical Building Block

    This compound functions as a C4 synthon in medicinal chemistry and pharmaceutical API intermediate production. Its activated double bond and methyl ester moiety allow tailored formation of active cores in specific cardiovascular and neurological drug candidates under GMP-setting batch synthesis.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF and EP general chapter requirements for intermediates
    • FDA cGMP 21 CFR Part 210 & 211 for pharmaceutical process control
    • Controlled substance precursor monitoring where applicable

    Typical usage ratio

    • Added at 5–25 mol% as a core intermediate, adjusted in R&D and commercial batches based on route optimization and residue minimization studies compliant with QbD principles.

    Downstream process integration

    • Introduced in early or middle-stage synthesis, used for selective Michael addition or ester-modification steps, followed by chromatographic purification for integration in API-side chain formation.

    Final product types

    • Pharmaceutical intermediates (e.g., beta-aminocarboxylates)
    • Investigational API scaffolds for CNS and antihypertensive drugs

    3. Flavor and Fragrance Ester Compounding

    Methyl 2-butenoate finds real use in the design of custom ester blends for fruity and green note profiles in industrial fragrance houses and non-food technical flavor bases, where its characteristic volatile profile supports fine-tuning of aroma accords under strict formulation guidelines.

    Industry compliance standards

    • IFRA (International Fragrance Association) Code of Practice
    • EU Regulation (EC) No 1223/2009 for cosmetics
    • ISO 9001:2015 for documented blending processes
    • Allergen labelling under EU/UK Cosmetics Regulation

    Typical usage ratio

    • Utilized at 0.01–1.0% (w/w) within the aroma concentrate or fragrance oil matrix, subject to organoleptic threshold studies and IFRA-recommended upper limits.

    Downstream process integration

    • Dosed at the final blending stage in closed reactor fragrance compounding lines, followed by chilling, pre-stability holding, and QC sensory panels review prior to dispatch.

    Final product types

    • Household fragrance concentrates (detergents, air fresheners)
    • Technical flavor additives for non-food products (e.g., oral care excipients)

    4. Polymer and Resin Modification Intermediate

    This material functions as an unsaturated ester modifier in selected specialty polymerizations to impart flexibility, lower glass transition temperature, and custom hydrophobicity in resin matrices. Direct downstream applications include coatings, adhesives, and specialty laminates that demand tailored mechanical properties and regulatory-compliant monomer residuals.

    Industry compliance standards

    • EU Regulation (EC) 10/2011 on food contact plastics for certain applications
    • ISO 14001:2015 for environmental process control
    • ASTM D256 (Polymer impact resistance testing)
    • RoHS Directive (2011/65/EU) for electronics-coating-compliant compositions

    Typical usage ratio

    • Incoporated at 2–8% (w/w) of total monomer charge, rate tuned for target crosslinking density and final polymer performance under pilot batch trials.

    Downstream process integration

    • Co-fed with bulk and comonomers in emulsion, bulk, or solution polymerization reactors prior to in situ polymer chain propagation and thermal cure cycles.

    Final product types

    • Flexible acrylic copolymer resins
    • Resinous surface coatings for electronics and appliances
    • Pressure-sensitive adhesive bases

    5. Chemical Research and Custom Synthesis Services

    We supply methyl 2-butenoate to industrial laboratories and contract synthesis providers conducting specialized organic synthesis, especially for R&D and pilot-scale campaign studies. Its defined reactivity supports novel route development, impurity pathway elucidation, and structural analog design in high-throughput environments subject to internal and client-specific quality controls.

    Industry compliance standards

    • GLP (Good Laboratory Practice) for analytical studies
    • ISO/IEC 17025 for laboratory testing and calibration
    • Material safety compliance under GHS/CLP hazard communication
    • Client-imposed specification protocols (CQA/CQC frameworks)

    Typical usage ratio

    • Applied from milligram to 5 mol% scale, dictated by synthetic target complexity; fixed by protocol for method development or process validation studies.

    Downstream process integration

    • Prepared as a core input for stepwise synthesis or parallel organic reactions, followed by NMR/GC-MS characterization and isolate hand-off to subsequent testing phases.

    Final product types

    • Reference standards
    • Custom organic intermediates
    • Compound libraries for screening
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    Competitive Methyl 2-Butenoate prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Methyl 2-Butenoate: Experience from the Manufacturing Floor

    Introduction from the Manufacturer’s Perspective

    Methyl 2-butenoate sees regular demand on our production lines because it delivers consistency and performance for formulators across several industries. I’ve observed its popularity grow as more manufacturers realize the practical benefits it brings to flavor, fragrance, and synthesis processes. Every batch that rolls out of our plant stands behind years of real-world experience, not just in cooking up pure chemicals but in understanding how people actually use them. Clients aren’t just chasing purity—they want predictable results, batch after batch, and that’s what guides our work.

    The Understated Role in Chemical Synthesis

    In the day-to-day business of chemical manufacturing, compounds like Methyl 2-butenoate rarely make headlines, yet they hold enormous value. This ester might seem modest compared to flashier molecules, but it occupies a pivotal place on many synthesis pathways. Methyl 2-butenoate often serves as an intermediate in creating higher-value products, including pharmaceuticals and flavors. In our plant, we handle it with the same attention to detail as more complex molecules.

    Getting the specifications right isn’t just about ticking off checkboxes. Even a small variance in moisture level or impurity loadout can throw off a downstream reaction or muddle a finished product’s profile. Nobody in operations fancies a phone call about a plant shutdown because of an off-spec intermediate. We see this ester slot right into Grignard reactions and Knoevenagel condensations, among many others. Clients from R&D to full-scale production rely on us to provide Methyl 2-butenoate that’s both dependable and clearly traceable.

    Product Model and Quality Control

    We produce Methyl 2-butenoate at several scales, catering to both kilo-lab researchers and bulk industry players. Consistency is non-negotiable. Raw materials arrive with certificates of analysis, but the real truth lies in what comes out of our reactors and distillation columns. In our facility, we run GC and NMR checks on every lot. Purity levels commonly run above 99%, and we keep water below the levels that can cause headaches for both flavorists and organic chemists. Optical clarity and freedom from color also matter, especially in applications where downstream discoloration would be unacceptable.

    When a batch diverges from our norms—say, a trace contaminant peeks above our threshold—the entire line pauses for a root-cause hunt. We’ve seen competitors cut corners, but that shortcut will never last. A client who sees unexpected spots on a chromatogram may never trust a brand again. This is why our QC teams have veto power over shipping. We run our shop with the kind of process discipline that means our buyers don’t get surprises, only the product they expect.

    Usage: Not Just Another Ester

    I’ve watched researchers come through our labs with test tubes, deploying Methyl 2-butenoate as a building block for higher-value molecules. Its reactivity profile sets it apart. Where other esters might bog down a reaction or introduce side products, this one often steps aside and lets the chemistry proceed. Its conjugated double bond gives it unique reactivity in additions and cyclizations. In some aromatic syntheses, a more saturated ester just won’t provide the electronic properties needed to steer a reaction. That’s where the double bond in Methyl 2-butenoate takes center stage.

    Talking to formulators in the fragrance industry, the sharp, fruity aroma of Methyl 2-butenoate gives character to pear or pineapple notes. Dilute it in alcohol, and even at low concentrations, it makes its presence known. Many lesser esters bring muddy or indistinct aromas, forcing perfumers to layer in additional chemicals. With this molecule, the scent comes out crisp and distinct. Gone are the days of having to chase after muddled base notes just to mask synthetic artifacts.

    Differences from Other Esters

    Not all methyl esters behave the same in the plant or in a formulation. The backbone of Methyl 2-butenoate—a four-carbon chain capped by a methyl group—might sound like a commonplace structure, but the placement of its double bond transforms its chemistry. For example, Methyl butanoate, lacking that double bond, brings a heavier, more buttery profile. In reactivity, the two molecules part ways entirely, with Methyl 2-butenoate’s unsaturation opening doors to conjugate additions, selective reductions, and more.

    In fragrances or flavors, using Methyl 2-butenoate can mean achieving brightness with fewer steps and simpler blending. Formulators often report that over-relying on saturated methyl esters stuffs a product with heavier, less ethereal notes, shifting the whole sensory balance off target. With the unsaturation here, top notes sing without crowding the finish. Our own quality team has even run side-by-side comparisons, confirming that our Methyl 2-butenoate holds its scent profile over time—a trait that matters when products need shelf longevity.

    Safety and Handling Considerations

    Experience on our production floors teaches a deep respect for the realities of working with volatile esters. Methyl 2-butenoate, as with most low-molecular-weight esters, brings both a strong odor and a tendency to volatilize. Our plant floors set strict protocols—ventilation rates, closed transfer systems, nitrile gloves, splash goggles—because skipping steps only invites trouble. The vapor, while less aggressive than some acyl chlorides we handle, can still irritate eyes and lungs.

    Those in smaller labs sometimes gloss over storage realities. We store our bulk inventory under inert nitrogen, with drum temperatures controlled. One slip—an open drum left near a heat source—can mean both safety risks and rapid quality loss as hydrolysis or oxidation kicks in. Downstream users who source from us find fewer surprises: a fresh ester, low on byproducts and less likely to misbehave during storage or handling. This stems from hard-won experience. Performance starts in the plant, not just in the bottle.

    Meeting Flavors and Fragrance Regulations

    Regulation of ingredients in food, fragrance, and cosmetics drove industry standards upwards. Here in our facility, we’ve lived through the shift from “good enough” to hard-line compliance, both from local authorities and export destinations. Our documentation doesn’t just reside in filing cabinets; each batch comes with data that’s ready for auditors or internal checks. For Methyl 2-butenoate, this means confirming absence of critical contaminants, ensuring correct labeling for allergens, and providing up-to-date safety and shipping documentation.

    Buyers in flavors and fragrances face ever-tighter scrutiny from their own customers, so they bring their questions directly to us. From provenance of raw materials to the dates of container tests, we field those questions with the records to back up our answers. Early in my career, documentation sometimes lagged production by weeks; now, it travels together, always up to date. Our clients’ reputations depend on this transparency, and so does our own.

    Reliability Through Continuous Improvement

    Chemicals aren’t commodities when every year brings new requirements. We dedicate resources to keeping our process technology both lean and robust. Over the years, we transitioned away from legacy distillation setups, investing in continuous flow systems that offer tighter temperature control and less downtime. These aren’t just internal wins—clients who depend on Methyl 2-butenoate see fewer delays and notice smaller lot-to-lot variation.

    Feedback loops run tight here. A customer returns a question about aroma fade or subtle off-notes, and our technical team follows up both in our pilot plants and client environments. These aren’t academic exercises—they shape our next production runs. Big changes sometimes begin with a small tweak: upgrade insulation here, double-verify a new solvent supplier there. We share notes across teams, bringing operators, QC specialists, and customers’ process engineers into the same conversation. The result? Fewer surprises and a living process that keeps pace with both customers’ ambitions and regulatory changes.

    Supply Chain Realities and Demand Cycles

    Supplying Methyl 2-butenoate on time demands more than just keeping reactors fed. Disruptions in supply chains—be they storms halting a key precursor or global freight congestion—land at the feet of manufacturers long before news trickles down to buyers. We track inventory with a conservative buffer, cycling in fresh raw materials and holding finished lots in climate-controlled storage. Over the years, we learned not to rely on single-source vendors for any input, no matter how reliable they seem. Hedging bets up front saves new headaches during crunch times.

    Market demand ebbs and flows. Some quarters see sudden spikes from fragrance clients rolling out new product launches; at other times, a surge in pharmaceutical research sparks more custom synthesis projects, pulling on available stock. Planning for these cycles means keeping both logistics teams and plant operators looped in at every step. Our senior managers watch not just purchase orders but also macroeconomic signals, predicting when to shift production volumes and when to bring in extra crews for longer runs.

    Technical Service: More than Selling a Drum

    Chemical manufacturing isn’t a “make it, ship it, forget it” business anymore. Every year brings more complex projects and sharper client questions about performance at both the bench scale and the plant scale. For Methyl 2-butenoate, technical service shapes everything from how our material integrates into others’ process streams to how it behaves under stress tests or extreme shelf conditions.

    Clients ask for advice: What sort of seal materials will hold up against repeated contact? How will minor changes in water content affect a specific reaction? Real answers don’t come from looking up generic literature—they come from having run the same experiments here, with our own people, under our own roof. Our technical advisors meet clients not just at trade shows but on plant tours and live troubleshooting calls, often bringing solutions that only appear obvious after you’ve made and sold tens of thousands of kilos over decades.

    Environmental Responsibility: Proof, Not Promises

    Public scrutiny of chemical manufacturing’s environmental impact has grown fierce, and in our industry, certificates and glossy pledges don’t solve the real problems. We focus on solvent recovery, waste minimization, and minimizing emissions at every reactor step. For a compound like Methyl 2-butenoate, which volatilizes easily, airtight transfers and closed-loop vapors capture aren’t optional. Our ops team tracks not just yields but energy consumption per batch, adjusting protocols after each quarterly review.

    Water usage, once ignored, gets careful attention now. We recycle cooling water and collect condensed vapors from distillation. Small changes, often invisible to outsiders, add up: energy use drops, emissions shrink, and our community neighbors notice the improvements. Some of our clients have their own sustainability benchmarks, so we share our metrics, letting them trace their own supply chain footprints back to specific practices within our facility. Real stewardship means running a clean operation now, not waiting for rules to force our hand later.

    Customization and Special Orders

    One constant in the market: few clients fit the textbook definition of a “standard user.” We often handle requests for custom-made Methyl 2-butenoate variants—odd blends, tighter impurity cutoffs, or specific packaging requirements. Our facility grew up around flexibility. Small kilo lots for R&D projects ship out with the same attention we give to bulk orders filling isocontainers for multinational flavors conglomerates. Our prep teams can fill bespoke drums, nitrogen-packed and clear-labeled, on tight deadlines when needed.

    I recall one case—pharmaceutical researchers asked for product distilled through a unique setup to avoid trace residues of certain metals. We reworked schedules, validated a new cleanout protocol, and delivered it on time. That sort of adaptability grew from years of having real chemists, operators, and problem-solvers under one roof. Over time, clients learn that this kind of customization beats chasing down off-the-shelf solutions from intermediaries who never see a plant floor.

    Shipping, Storage and Best Practices

    Shipping Methyl 2-butenoate isn’t just a matter of slapping a shipping label on a drum. This ester, thanks to its volatility and flammability, needs careful packing, compliant documentation, and temperature management to reach clients in top condition. Every container leaves our plant sealed, with vented bung options when appropriate, and captured under our tracking system. We’ve overhauled our labeling dozens of times to cut down the risk of confusion or mishandling.

    End-users often call about storage recommendations. We advise tight sealing, cool conditions, and avoiding both direct sun and open flames. Any spillage cleanup draws on protocols we’ve refined through real incidents, not just paperwork. Our staff keeps spill kits on hand—absorbents, neutralizers, and backup personal protective equipment all at the ready. On those rare occasions when clients report shipping-related quality dips, we follow up with root-cause checks at both ends before offering replacement or credit. This commitment doesn’t spring from fine print, but from a sense of mutual respect that comes from handling thousands of drums and never forgetting that a single mistake travels fast in global supply.

    The Difference Manufacturer Expertise Makes

    Anyone can source a low-grade methyl ester from a catalog. The difference in practice comes from knowing the precise dance a molecule must perform in each customer’s lab or plant. I’ve seen buyers point to identical CAS numbers from different suppliers and get wildly different results. That difference stems from production nuances—how side reactions are suppressed, how trace impurities drift out, and how final lots are polished and packed. Clients appreciate that they can call us directly, bypassing layers of traders, and talk to someone who’s overseen an actual production run.

    Methyl 2-butenoate’s real value comes alive when manufacturers stand behind both their processes and products. We don’t hide behind distributors or resellers. Years spent refining every parameter—temperature ramps, agitation rates, raw material screening—lead to product that performs across the largest and smallest scales. This transparency isn’t a marketing slogan for us. Long-standing relationships with buyers, plant operators, and R&D chemists build the kind of trust that can only come from owning the process end to end.

    The Road Ahead

    Chemistry keeps moving, and so do the challenges facing those who supply and work with compounds like Methyl 2-butenoate. New end-use applications in green chemistry, agrochemicals, and specialty polymers keep us on our toes. We’re investing in both skills and technology, bringing automation to tricky synthesis steps without losing the hands-on wisdom gained from years on the plant floor. We approach every change as a chance to make the product and the process safer, cleaner, and more effective for everyone who relies on it.

    Our belief remains simple: chemicals are only as reliable as the people and processes that produce them. Each drum we ship is a statement of craftsmanship and integrity, not just a commodity moving through the system. As long as people need crisp top notes in a perfume, precise chemistry in a plant, or reliable scale-up from bench to bulk, we’ll keep listening, improving, and delivering Methyl 2-butenoate built on experience, not just promise.