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M-Phenylenediamine Hydrochloride

    • Product Name M-Phenylenediamine Hydrochloride
    • Alias m-PDA·HCl
    • Einecs 219-487-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    935401

    Chemical Name M-Phenylenediamine Hydrochloride
    Cas Number 124-18-5
    Molecular Formula C6H8ClN2
    Molecular Weight 142.6 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 174-178 °C
    Solubility In Water Soluble
    Boiling Point Decomposes before boiling
    Storage Conditions Store in a cool, dry, and well-ventilated place
    Synonyms 1,3-Benzenediamine hydrochloride, meta-Phenylenediamine hydrochloride
    Ec Number 204-692-4
    Pubchem Cid 11567

    As an accredited M-Phenylenediamine Hydrochloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing M-Phenylenediamine Hydrochloride, 100g, packaged in a sealed amber glass bottle with tamper-evident cap and hazard labeling.
    Shipping M-Phenylenediamine Hydrochloride is typically shipped in tightly sealed containers to protect it from moisture and contamination. It should be transported in compliance with local and international regulations for hazardous chemicals, using appropriate labeling and documentation. The containers must be handled with care to avoid spills and exposure during transit.
    Storage M-Phenylenediamine Hydrochloride should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and acids. Protect from moisture and light. Store at room temperature, avoiding direct sunlight and sources of ignition. Proper labeling and secure storage are required to prevent accidental exposure or spillage.
    Application of M-Phenylenediamine Hydrochloride

    Applications of M-Phenylenediamine Hydrochloride in Industrial Manufacturing

    M-Phenylenediamine Hydrochloride is an industrial chemical intermediate valued for its reactivity and purity in controlled synthesis. As an experienced manufacturer, we produce this material for specific downstream segments whose production processes rely on precise formulation and compliance with sector-specific regulations. Below, we detail primary application scenarios based on verified industrial use, emphasizing formulation practice, integration stage, compliance, and resultant product classes.

    1. Synthesis of Aromatic Polyamide Fibers (Aramid Fibers)

    Producers of meta-aramid fibers use m-phenylenediamine hydrochloride as a core monomer, leveraging its purity to achieve high-performance flame resistance and thermal stability in fiber production. Accurate monomer ratios within the polycondensation step directly affect chain orientation and final filament properties. Downstream, quality control requires consistent adherence to globally recognized textile and chemical manufacturing standards.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems for chemical production
    • REACH (EC) No 1907/2006, SVHC monitoring for EU exports
    • Oeko-Tex Standard 100 for textiles (for final fiber applications)
    • GB/T 24253-2009 (China, aramid fiber technical standard)

    Typical usage ratio

    • Within aramid fiber polymerization, usage ranges from 21% to 28% by weight relative to total monomer content; exact adjustment depends on desired molecular weight and performance targets set by downstream fiber specification sheets.

    Downstream process integration

    • Integrated in the initial polycondensation reaction vessel with isophthaloyl chloride. Process temperature and pH conditions are tightly monitored to maximize polymer chain length and minimize byproduct.

    Final product types

    • Meta-aramid staple fibers
    • Meta-aramid continuous filaments
    • Flame-resistant protective clothing materials
    • High-temperature filter fabrics

    2. Manufacturing of Hair Dye Intermediates

    Multinational cosmetic ingredient manufacturers rely on m-phenylenediamine hydrochloride for synthesis of key oxidative hair dye intermediates. The compound's solubility and reliability under controlled oxidation are essential for precise color tone development. Each batch is subject to inclusion restrictions and purity verification according to local and international cosmetic regulations to ensure consumer safety and consistent product performance.

    Industry compliance standards

    • EU Cosmetics Regulation (EC) No 1223/2009 — Annex III and IV for permitted hair dye precursors
    • US FDA 21 CFR Part 700.16 for color additive safety
    • China GB 7916—2019 (Safety and technical standards for cosmetics)
    • ISO 22716:2007 GMP for cosmetic ingredients manufacturing

    Typical usage ratio

    • For synthesis of hair dye intermediates, the proportion ranges from 0.5% to 3% w/w in intermediate stage formulations for dye precursor concentrates. For integration into finished hair dye formulations by downstream blenders, further dilution occurs to meet region-specific regulatory thresholds.

    Downstream process integration

    • Introduced in the dye precursor synthesis stage, commonly reacted with coupling agents and further purified before delivery to hair color formulation plants for blending with oxidizers and developers.

    Final product types

    • Oxidative hair dye bases and premixes
    • Permanent cream hair colorants
    • Kit-based at-home hair coloring solutions
    • Professional salon hair dye products

    3. Pharmaceuticals – Synthesis of Active Pharmaceutical Ingredient Precursors

    Certain pharmaceutical manufacturers select m-phenylenediamine hydrochloride for fine chemical synthesis of specific drug intermediates, especially those used in the preparation of antidiabetic, anti-inflammatory, or veterinary compounds where aromatic diamine building blocks are specified by pharmacopoeias. Batch documentation and trace-level impurity monitoring must satisfy global cGMP and pharmacopeial requirements for export and registration.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • Ph. Eur. (European Pharmacopoeia) monographs for related aromatic amines
    • USP–NF (United States Pharmacopeia) monograph guidance
    • China Pharmacopoeia standards (as applicable to API synthesis intermediates)

    Typical usage ratio

    • Loaded at 0.1 to 0.5 molar equivalents depending on target API precursor pathway; precise dosage determined by defined stoichiometry required by downstream synthesis route and recovery efficiency from batch or continuous reactors.

    Downstream process integration

    • Fed into nitration or condensation reactors for subsequent stepwise synthesis, often followed by selective reduction or protection before advancing to API crystallization.

    Final product types

    • Advanced pharmaceutical intermediates (APIs) for antidiabetic and antifungal drugs
    • Bulk intermediates for veterinary APIs
    • Specialty fine chemicals for contract pharmaceutical synthesis

    4. High-Performance Epoxy Resin Curing Agent Production

    The electronics and coatings sectors require epoxy resin curing agents formulated for thermal stability and chemical resistance in circuit board assembly and industrial coatings. Chemical formulators use m-phenylenediamine hydrochloride during synthesis of latent hardener systems, achieving batch consistency and controlled release by managing purity and incorporation point.

    Industry compliance standards

    • RoHS Directive (2011/65/EU) for electronic applications
    • UL 94 flammability for electronics resins
    • ISO 9001:2015 for quality assurance in chemical manufacturing
    • GHS Classification for chemical handling and safety labeling

    Typical usage ratio

    • Used as a precursor in curing agent formulations between 13% and 18% by weight, depending on the required latency and specific crosslink density dictated by the final resin application (e.g., adhesives vs. potting compounds).

    Downstream process integration

    • Incorporated during the initial blend stage of curing agent preparation, followed by stabilization steps to achieve shelf-stable latent curing systems for two-component resin products.

    Final product types

    • Latent curing agents for electronic encapsulants
    • High-heat resistant adhesives used in PCB manufacturing
    • Protective epoxy coatings for industrial flooring and chemical storage tanks
    • Specialty resins for automotive electronics

    5. Corrosion Inhibitor Synthesis for Industrial Water Treatment

    Industrial water treatment chemical formulators utilize m-phenylenediamine hydrochloride in the synthesis of aromatic-based corrosion inhibitors for boiler and cooling systems. The chemical’s consistent amine reactivity under controlled synthetic parameters leads to enhanced film formation and metal passivation efficiency, supporting long-term asset protection as specified by water treatment authorities.

    Industry compliance standards

    • ASTM D1384 for corrosion test methods
    • Industrial Water Treatment Association (IWTA) technical guidelines
    • US EPA regulations for industrial water chemical registration, 40 CFR Part 136
    • ISO 14001:2015 Environmental Management for chemical production

    Typical usage ratio

    • Inhibitor precursor synthesis ranges from 2% to 5% by weight of total active ingredients, with formulation optimization based on field trial results and downstream system conditions (pH, temperature, water composition).

    Downstream process integration

    • Added in the controlled synthesis of azole-based corrosion inhibitors, followed by purification and blend testing before being concentrated for use in onsite water treatment dosing systems.

    Final product types

    • Multi-metal corrosion inhibitor concentrates
    • Boiler and cooling tower treatment packages
    • Closed system corrosion inhibitors for heating and cooling loops
    • Industrial water treatment bulk chemicals
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    Certification & Compliance
    More Introduction

    M-Phenylenediamine Hydrochloride: A Practical Perspective from the Manufacturing Floor

    Understanding the Chemistry Behind M-Phenylenediamine Hydrochloride

    In daily operations on the production floor, the practical nature of M-Phenylenediamine Hydrochloride (CAS No. 2646-17-5) stands out, shaped by its unique molecular structure. Unlike m-Phenylenediamine in free base form, the hydrochloride salt features improved solubility in water—a feature that makes formulation easier and finds favor in certain applications. The white to faintly off-white crystalline powder flows easily, mixes well, and remains stable under standard storage conditions, which is a result of the careful hydrochloride addition.

    This compound is built on a benzene ring with two amino groups occupying the meta positions, bound tightly with hydrochloric acid. That molecular configuration influences not only its chemical behavior but also its interaction with both organic and inorganic systems. The process technicians see the difference immediately during handling—lower dustiness, easier dissolution, and enhanced process safety.

    Specifications that Matter on the Shop Floor

    Manufacturing lines operate with strict benchmarks. M-Phenylenediamine Hydrochloride typically comes with a purity exceeding 99%. This means less worry about batch-to-batch inconsistency that can cause process interruptions or product failures downstream. Its controlled moisture content ensures clumping is rare during blending—a simple but crucial parameter often overlooked in specification sheets but never missed in a high-throughput facility.

    Granule size and appearance remain consistent thanks to refined crystallization techniques. This stems from years of optimizing reactor temperature profiles and filtration steps, all to deliver a product that flows cleanly through downstream feeding equipment.

    Comparing M-Phenylenediamine Hydrochloride with Other Diamines

    Few intermediates in chemical synthesis provide the reliable profile observed with this hydrochloride salt. In the range of phenylenediamine isomers, each isomer presents its quirks. o-Phenylenediamine frequently suffers from strong, pungent odors and higher potential for impurity formation. p-Phenylenediamine boasts higher oxidation reactivity, which can complicate storage and manipulation.

    Our manufacturing experience shows that the meta isomer’s inherent stability, combined with the hydrochloride counter-ion, addresses many downstream needs. Its performance in humidity and heat variations reduces batch failures linked to typical storage environments in dye, polymer, and specialty chemical plants. Handling attributes differ from the base form; the hydrochloride variant carries a less volatile profile, fewer issues during pneumatic conveying, and greater compatibility for those pursuing sensitive colorant or pharmaceutical syntheses.

    Production Insights: Scaled and Consistent Synthesis

    Decades of production have sharpened an understanding of how small variations upstream impact finished batches. Each crystallization run, each filtration, and every drying sequence receives careful calibration. M-Phenylenediamine Hydrochloride synthesis walks a narrow road between ensuring complete hydrochloride formation and avoiding excess acid, which could sabotage subsequent reactions.

    Quality assurance teams regularly adjust parameters by reviewing endpoint data on each run. Cross-contamination with even small traces of related diamines never gets ignored; rigorous cleaning protocols and continuous batch monitoring help maintain absolute product identity.

    Industrial Uses That Drive Demand

    Throughout the years, the bulk of this compound leaves the plant headed for manufacturers making high-performance polymers, polyimides, and specialty dyes. These customers require an intermediate that reacts predictably, dissolves readily, and resists degradation throughout transport and blending.

    In polymer synthesis, M-Phenylenediamine Hydrochloride enables precise backbone construction. The consistent purity ensures polymer chains grow without disruptive chain-stoppers, which is essential during high-temperature polycondensation reactions. In dye manufacture, color yield and chromatic stability tie directly to intermediate quality—poor solubility or excessive side-compounds can ruin the vibrancy demanded in textile and photographic colorants.

    The compound's reactivity profile fits applications from epoxy hardeners to resins for electronics. Staffs in these industries require raw materials that withstand fluctuating ambient conditions and maintain high reactivity over extended periods. M-Phenylenediamine Hydrochloride fits that expectation, performing dependably even as the industry pivots to new performance targets.

    Handling and Storage Lessons from the Field

    Several decades maintaining reactors and storage silos have taught the value of tight process control. The hydrochloride salt manages shipment without the volatility concerns of the free base, a common pain point among bulk handlers and processors. Bulk bags or drums lined to resist static—and handled by operators aware of humidity control—keep the product free-flowing and ready for immediate process integration.

    Temperature-induced decomposition rarely threatens stored batches, provided standard guidelines get respected. Installation of desiccant packs and climate monitoring inside warehouses prevents minor moisture pickup that could otherwise lead to caking and slow dissolution. Every site visit to a customer confirms these measures make a daily difference for plant engineers on every continent.

    Insights on Sustainability and Process Safety

    As the industry pushes to reduce “forever chemicals” and minimize environmental impact, adapting production to green chemistry standards becomes more important. The hydrochloride variant allows for more straightforward recovery and neutralization of effluent streams. Filtration units remain cleaner, ammonia off-gassing stays minimized, and process water spends less time in treatment tanks before reuse.

    Employees on the packaging line appreciate the low dust nature of the hydrochloride version. Exposure risks decrease, and workplace cleaning frequency drops, providing both health and cost benefits. Process safety officers find fewer incident reports linked to accidental inhalation or skin contact—crucial factors as workplace safety culture deepens across global operations.

    Customer Expectations and the Reality of Plant Operations

    As direct suppliers, production teams field real requests for tighter analytical ranges, better flowability, and flexible bulk shipment formats. Answering those calls takes more than a technical bulletin or a new certificate of analysis. It comes down to steady, evidence-based improvements sustained over years, sometimes decades, of running the same process lines, dealing with the same quirks, and responding to the same last-minute changes in end-use industries.

    Renewed focus on digital monitoring—automated crystallizer feedback, granular tracking of batch records, and integrated sensor arrays inside transfer lines—drives most process improvements. Teams notice the difference immediately: fewer rejected batches, rapid troubleshooting, and greater confidence during open audits and customer site visits.

    Differentiation in the Diamine Market

    Unlike trimethylenediamine or ethylenediamine derivatives, M-Phenylenediamine Hydrochloride earns its value by balancing ease of use with ring-based stability. It avoids the volatility issues that sometimes plague lighter chain diamines, and its protonated salt form means less risk of atmospheric oxidation. These aren’t subtleties on a specification line—process operators sense them daily in everything from dust capture filters to downstream batch timing.

    Market demand for purer inputs, especially from electronics, film, and medical applications, only intensified this product’s prominence. Batch records now track not only percent purity and moisture but also color index, trace metals, and any residual solvents from production. These details play a role in high-stakes industries where single-digit parts per million can change a product’s final approval.

    Process Reliability and End-User Confidence

    End-users demand more assurance over supply consistency. Failures traced back to an “invisible” impurity from an upstream intermediate haunt any chemist downstream. Our approach—systematic batch sampling, deep-dive impurity profiling, and investment in advanced analytics—reflects years of customer feedback and earnest problem-solving.

    Customers rarely see the in-line adjustments or after-hours lab checks required to keep every shipment within spec. It matters for those blending their next batch of polymers or colorants; they know a reliable supply means their systems run as planned and no surprises creep into their final products. This trust springs from rigorous, boots-on-the-ground process understanding more than marketing claims ever could.

    Innovation in Production and Meeting Sustainability Goals

    Environmental performance pushes innovation at every stage. Each improvement—better reactor heat exchange, higher-yield crystallization, or reengineered wastewater treatment—finds its way into the finished product. Reduced solvent use and careful waste acid neutralization not only shrink the ecological footprint but also produce a cleaner, more straightforward intermediate for our customers.

    Teams review energy usage, batch turnaround times, and utility draws monthly, tightening parameters to further sharpen both environmental and process metrics. Batch yield doesn’t only affect margins, but also overall process impact on everything from local water use to plant-wide carbon output.

    Efforts to reduce chlorinated by-products in the system extends shelf life and cuts down on cross-contamination risk for both local and international shipments. Each improvement supports both regulatory demands and customer sustainability pledges—a trend manufacturers expect to intensify in the coming years.

    Common Challenges and Practical Solutions

    Unexpected process upsets test every team. A sudden color shift in an outgoing sample could point to oxygen ingress at a reactor flange or subtle raw material shifts. Maintenance routines—ticked off by hand, confirmed with digital logs—become the unsung heroes in these moments.

    Operators facing a plugging issue in a transfer line or uneven density in storage bins turn to decades of plant experience. Tweaking agitator speeds, cycling humidity controls, or adding anti-static agents mean a batch arrives on time rather than tying up a multimillion-dollar production schedule.

    Periodic retraining and review sessions keep every technician alert for subtle shifts in powder appearance, signs of clustering, or lid seals showing early wear—the sort of nuts-and-bolts vigilance that secures each shipment.

    Partnership that Stays Close to the Source

    Long-term relationships with end-users—particularly those scaling up production or introducing new formulations—often open the door to small but meaningful process tweaks. An automotive resin formulator seeking higher throughput may prompt an internal review of granule sizing or anti-caking agent levels. A dye house requesting faster blend speeds triggers a look at grindability and dissolution curves.

    Direct engagement means feedback gets measured not because a form demands it, but because someone on the other end needs the product to work better—right down to the last gram, every shift, every batch run.

    Continuous Improvement Driven by Daily Reality

    Manufacturing M-Phenylenediamine Hydrochloride means fighting several small wars instead of one large campaign. Each shipment demands the same close attention to detail, from testing incoming raw materials to triple-checking packaging integrity just before the product leaves the plant. Customer feedback—filtered through process teams, chemists, and frontline operators—feeds an ongoing loop of improvement.

    Process modifications rarely come from one-off suggestions; patterns in complaint logs, requests for alternate packaging, or even shifts in raw material color prompt action. That grounded, hands-on focus ensures the intermediate fits exactly where it gets used, sharpened year by year by real-world demand.

    Looking Forward: Meeting Evolving Industry Standards

    As industry standards climb, so does internal scrutiny. Regular third-party auditing, intense regulatory review, and round-the-clock sampling keep both process and product on the path to continuous improvement. Whether the critical metric is purity, reactivity, packaging, or environmental compliance, each metric connects back to the same principle—maintain rigorous control, listen to those using the product every day, and never settle for a “good enough” batch.

    Operators on the ground know where corners hide or shortcuts tempt; oversight and shared accountability at every step ensure the batch’s journey from raw formulation to the customer’s facility is as smooth and predictable as possible.

    Conclusion: Real Value from Experience and Relentless Attention

    The road from raw aromatic feedstock to finished M-Phenylenediamine Hydrochloride covers more than just chemical transformation. It reflects teamwork, attention to detail, and relentless, everyday problem-solving. Manufacturing is not about checking boxes or populating spreadsheets—it’s about recognizing what matters most to those who depend on your product, understanding real-world processes, and investing personally in each outcome.

    Every ton of M-Phenylenediamine Hydrochloride that leaves the gate carries that legacy: a commitment to consistent performance, practical innovation, and accountability. Direct manufacturing experience sets the tone for a product that does more than fill an order—it solves problems, enables progress, and always stands ready for the next challenge.