Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Isopropyl 2-Chloropropionate

    • Product Name Isopropyl 2-Chloropropionate
    • Alias Isopropyl 2-chloropropanoate
    • Einecs 239-563-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    739642

    Chemicalname Isopropyl 2-Chloropropionate
    Molecularformula C6H11ClO2
    Molarmass 150.60 g/mol
    Casnumber 6303-21-5
    Appearance Colorless liquid
    Boilingpoint 146-148°C
    Density 1.062 g/cm3
    Flashpoint 43°C
    Refractiveindex 1.422
    Solubilityinwater Immiscible
    Vaporpressure 2.3 mmHg at 25°C

    As an accredited Isopropyl 2-Chloropropionate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500 mL amber glass bottle with screw cap, chemical label reads "Isopropyl 2-Chloropropionate," hazard pictograms, batch and expiry dates.
    Shipping Isopropyl 2-Chloropropionate should be shipped in tightly sealed containers, protected from light, moisture, and incompatible materials. Transport in compliance with local, national, and international regulations for hazardous chemicals. Use proper labeling, and ensure containers are handled carefully to prevent leaks, spills, or breakage. Store in a cool, well-ventilated area during transit.
    Storage Isopropyl 2-Chloropropionate should be stored in a tightly closed container in a cool, dry, and well-ventilated area away from heat sources, direct sunlight, and incompatible substances such as strong oxidizers and acids. Avoid moisture exposure. Use non-sparking tools and prevent static discharge. Store at recommended temperatures as specified by the manufacturer. Keep out of reach of unauthorized personnel.
    Application of Isopropyl 2-Chloropropionate

    Applications of Isopropyl 2-Chloropropionate in Industrial Manufacturing

    Isopropyl 2-Chloropropionate serves as a specialized raw material in several targeted chemical sectors. Our factory supplies this intermediate to industrial clients who demand high purity and controlled quality for patented synthesis and proprietary production processes. The following use cases reflect real downstream manufacturing scenarios with defined process roles for this compound.

    1. Agrochemical Active Ingredient Synthesis

    Major agrochemical formulators use Isopropyl 2-Chloropropionate in the synthesis of selective herbicide and fungicide active ingredients. This ester acts as an alkylating agent during formation of specific heterocyclic structures and enhances yield in chlorinated active ingredient chains. Operators charge it into closed reactors under inert gas protection during batch synthesis, and adjust its addition rate based on seasonal production planning and the impurity profile of co-reactants. Strict in-process controls ensure proper incorporation and minimize byproducts.

    Industry compliance standards

    • FAO/WHO Technical Specifications for herbicide APIs
    • ISO 9001:2015 certified quality management for agrochemical intermediates
    • European Union Regulation (EC) No 1107/2009 guidelines for plant protection product intermediates
    • REACH Annex IX substance registration requirements

    Typical usage ratio

    • Applied at 0.4%–3% molar ratio relative to other reactants, with adjustments according to synthetic route optimization and crop season requirements

    Downstream process integration

    • Loaded during initial charge or added incrementally at controlled temperature (50–85°C)
    • Enters amidation, esterification, or alkylation stages for targeted molecule construction
    • Monitored by in-line gas chromatography for completeness of reaction

    Final product types

    • Chlorinated triazole fungicide technical concentrates
    • Phenoxy herbicide intermediates
    • Sulfonylurea herbicidal actives
    • Finished emulsifiable concentrates and suspension concentrates

    2. Pharmaceutical Intermediate for Antimicrobial Synthesis

    Several pharmaceutical companies purchase Isopropyl 2-Chloropropionate as a critical acylating intermediate in the multi-step synthesis of select antimicrobial and antifungal agents. Its controlled reactivity supports precise structural modifications aligned with pharmacopeial requirements. The material enters closed-system reactors under GMP guidance, and operators adjust dosages according to the drug master file (DMF) specifications for each API candidate. Downstream purification steps ensure trace removal with analytical batch release testing.

    Industry compliance standards

    • ICH Q7A Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF monographs and analytical chapter compliance for relevant APIs
    • EU Directive 2001/83/EC for medicinal products for human use
    • FDA DMF submission requirements (21 CFR Part 314)

    Typical usage ratio

    • Dosage controlled at 0.8–2.5 molar equivalents, dependent on the specific antimicrobial synthetic route and desired impurity levels

    Downstream process integration

    • Introduced as a reactant in the acylation or esterification step
    • Reactive stages held under nitrogen; in-process HPLC monitors residual unreacted intermediate
    • Subject to intermediate stage validation and in-process controls to meet ICH standards

    Final product types

    • Antifungal imidazole intermediates
    • Bacteriostatic aromatic ester derivatives
    • Finished API crude and refined bulk for outsourced pharmaceutical formulation
    • Registered DMF intermediates for contract manufacturing

    3. Specialty Monomer Modification in Polymer Production

    Leading polymerization plants integrate Isopropyl 2-Chloropropionate to introduce controlled chlorinated ester functionality into acrylic and methacrylic polymer chains. This addition modifies polymer flexibility and surface adhesion properties in end-use applications such as protective coatings, specialty adhesives, and engineering plastics. The compound feeds continuously into copolymerization reactors, and production engineers finetune its inflow to align molecular weight distribution and target mechanical performance with quality specifications.

    Industry compliance standards

    • ISO 14001:2015 environmental management for polymer operations
    • ASTM D256, D638, D1002 standards for polymer performance testing
    • RoHS Directive (EU 2011/65) restricted substances compliance for electronic and industrial plastics
    • REACH registration for monomers and additives

    Typical usage ratio

    • Fed at 1.0–3.5% by weight in monomer mixture, based on desired polymer chain functionality and final product application tolerance

    Downstream process integration

    • Metered addition to pre-polymerized acrylate or methacrylate monomer blends
    • Reacts under controlled thermal conditions (60–120°C) for chain extension
    • Polymer produced subjected to gel permeation chromatography and FTIR quality checks

    Final product types

    • Adhesive-grade specialty acrylics
    • Protective coating films
    • High-clarity plastics for automotive and electronics
    • Pressure-sensitive adhesive formulations

    4. Fine Chemical Intermediate for Fragrance Esterification

    Perfume and aroma compound manufacturers use Isopropyl 2-Chloropropionate in the synthesis of select ester-based fragrances and specialty aroma chemicals. The compound undergoes controlled nucleophilic substitution during batch esterification, imparting a chlorinated ester note into the fragrance backbone. Operators charge precise quantities into jacketed glass-lined reactors equipped for trace odor control, and adjustments follow the olfactory profile required for different consumer goods segments, particularly in premium cosmetic bases.

    Industry compliance standards

    • IFRA Code of Practice for fragrance ingredient safety
    • ISO 9235 definition for natural and synthetic aroma chemicals
    • EU Cosmetics Regulation (EC) No 1223/2009 annex for restricted and allowed fragrance compounds
    • GMP EFfCI certification for personal care ingredients

    Typical usage ratio

    • Charged at 0.2–1.5% of total batch composition, with variations depending on finished fragrance strength and tonality requirements

    Downstream process integration

    • Introduced in the key esterification stage under temperature control (30–75°C)
    • Final ester purified by fractional distillation and subjected to GC-olfactometry profile confirmation
    • Batches filtered and standardized for fortification blends

    Final product types

    • Synthetic musk esters
    • Fine fragrance base compounds
    • Cosmetic-grade aroma adducts
    • Personal care and toiletry product fragrance blends
    Free Quote

    Competitive Isopropyl 2-Chloropropionate prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing Isopropyl 2-Chloropropionate: Precision in Modern Chemical Synthesis

    We have spent years refining our process for producing Isopropyl 2-Chloropropionate, a versatile intermediate trusted in a range of sectors. Our engineers and chemists work with this material daily, from initial synthesis through purification and packaging. The familiarity we have gained with its properties and its behavior in different reaction environments means we know what producers and downstream users care about: purity, reactivity, and reproducibility.

    Established Specifications and Consistent Output

    The product we deliver carries a model developed from repeated lab scale and industrial runs, which ensures its chemical structure—C6H11ClO2—remains stable and reliable from drum to drum. We dial in purity at above 98% as verified by GC analysis, since downstream processes do not accommodate variable input quality. As manufacturers, we never compromise on traceability: every batch runs through our identification systems. A faint, slightly fruity odor lets a trained operator immediately recognize its presence, and its fluid consistency at room temperature means it pours smoothly, eliminating issues during transfer and metering into reactors.

    By emphasizing actual handling over theoretical parameters, we pay attention to details others overlook. If we see any haze—perhaps from trace moisture—our line operators reroute it to reprocessing before it ever leaves site. That consistency creates predictability, which chemists building up esters or chlorinated intermediates in their own plants appreciate. In large syntheses, a single faulty drum can compromise dozens of hours of work, so we never ship product that falls below our benchmarks.

    Where Isopropyl 2-Chloropropionate Proves Essential

    Working in the chemical industry long enough offers plenty of chances to see which materials truly pull their weight. Isopropyl 2-Chloropropionate stands out as a steady performer in fine chemical synthesis. Formulators and developers rely on it when building agrochemical actives, especially herbicides and insecticides, due to its ability to bridge key molecular frameworks. In the pharmaceutical world, our partners lean on this ester for constructing certain chiral intermediates, where minor changes in purity can mean significant losses in yield and downstream reproducibility.

    In practice, we see teams blending this material into multistep syntheses, where its reactivity with amines or alcohols allows for precise and controlled transformations. We frequently consult with process chemists who want advice on minimizing side reactions or on scaling up from lab batches, and years of hands-on experience let us offer practical advice—sometimes as simple as warming up a transfer line or switching out a gasket material to avoid contamination from elastomer swelling.

    One production manager told us that he never really appreciated the difference between a reagent produced by the original manufacturer and one from a broker until a failed batch traced back to a tiny impurity that slipped past an unwitting distributor. That sealed his team’s commitment to purchasing direct from the source, where full visibility into materials handling and batch analytics stays intact.

    Handling Safety, Storage, and Regulatory Reality

    We do not ignore the challenge of working with chlorinated esters. Isopropyl 2-Chloropropionate calls for respect and understanding—our facilities use closed loop systems and local exhaust, minimizing exposure and reducing the risk profile for line operators. We store the product in polyethylene and lined drums without incident, thanks to lessons learned decades ago during our early scale-up days. The ester remains stable in cool, ventilated spaces, and we avoid metal containers that could catalyze hydrolysis or color changes over time.

    Regulations impact every aspect of our business, from transportation to waste disposal. Most jurisdictions classify this material under hazardous goods—though it does not present extreme toxicity, its chemical behavior means spill containment and labeling require vigilance. Our distribution team coordinates with logistics providers who specialize in chemical cargo, and we lead training sessions regularly to keep all staff aware of the latest handling protocols.

    On international shipments, we always include a detailed Certificate of Analysis drawn directly from our in-house QA assays. This transparency forms the groundwork for long-term trust with multinational customers navigating increasingly complex import frameworks. Regulatory agencies visiting our site see our traceability and testing logs first-hand; the result is a mutual understanding about safety and environmental responsibility in modern chemical manufacture.

    The Core Differences: What Sets Our Product Apart

    We hear from customers who ask about differences between Isopropyl 2-Chloropropionate and its close cousins—like methyl, ethyl, or butyl chloropropionates. Years of running comparative batch syntheses and pilot trials make a few facts clear. Isopropyl esters, thanks to their steric profile, often offer an optimal mix of reactivity and physical handling. Methyl variants can hydrolyze more rapidly and sometimes trigger byproduct formation if water traces enter a reaction. Butyl options, on the other hand, bring heavier molecules that may slow reaction times or complicate downstream separations at scale.

    Chemists value the isopropyl ester for its unique blend of volatility and selectivity. It distills cleanly during purification steps and does not cling stubbornly to reactor walls, reducing solvent use during cleanup. That impacts cycle times, cost calculations, and, over many campaigns, profitability. Engineers on our own plant floors double-check specifications because run data consistently prove that this compound performs as projected: reliable boil-off at around 162 to 165°C, minimal color formation, no unexpected residue in filtration trains.

    Compared to more widely traded materials, Isopropyl 2-Chloropropionate options from third-party blenders can introduce batch-to-batch variability. Trace stabilizers, impurities, or handling artifacts sometimes slip in unnoticed—especially with long supply chains. Direct sourcing from an actual manufacturing facility avoids these pitfalls. As a manufacturer, we run full-spectrum analytics, including NMR and GC-MS, on every lot, maintaining control at every step so external contamination stays out.

    Applications from Lab Bench to Ton-Scale Synthesis

    Ten years of feedback from industrial clients have shaped how we formulate and package this ester. Our biggest agrochemical customer once struggled with unreacted starting material in their fenoxycarb campaign until we worked alongside their technicians on-site to analyze blend ratios and feed rates. For a pharmaceutical partner, a switch to our higher-purity grade cut two days from their workup thanks to a sharper and faster esterification window. In both cases, the difference in output came from reliable input.

    In the laboratory, small quantities of Isopropyl 2-Chloropropionate let synthetic planners develop new catalysis protocols, test selectivities, or model possible routes before scaling up. Academic collaborators tell us that our documentation and openness about impurities helps them model reaction mechanisms more accurately, shaving weeks off their research timelines. They don’t want generic safety sheets—they want to see the actual spectra. We respond with batch-specific reports included in every delivery.

    On larger scales, automated dosing can only keep up if the physical properties stay predictable. The pour point of our product, just below room temperature, eliminates nozzle blockages and streamlines automated feed systems. Disposal remains manageable compared to alternative chlorinated intermediates, thanks to its favorable volatility and lower solubility in aqueous waste streams.

    Solving Sourcing and Quality Mysteries

    Before we brought Isopropyl 2-Chloropropionate into our own catalog, sourcing this product meant uncertainty—was supply coming from a custom operator, a batch splitter, or a mega-plant with little focus on niche intermediates? Early customers regularly shared stories of surprise contaminants, fluctuating supply timelines, and missed deadlines that hurt project momentum. Many of the issues boiled down to lack of visibility and the absence of a consistent reference sample.

    Our approach changed that. Batches stay linked to source reactors via unique lot numbers; each output run passes blind duplicate sampling, with finished goods released only after technical manager review. If there’s an issue detected downstream, our records enable rapid tracing all the way to original material inputs. We routinely invite client QA teams for plant tours, and their analysts confirm the confidence that direct-sourced, closely-watched material brings. Decision-makers can plan projects knowing the intermediate in use comes from a verifiable source with skin in the game.

    Continuous Improvement and Technical Collaboration

    Nothing in our process stands still. As downstream users run larger campaigns, their evolving needs shape our own upgrades. Improved column designs in the distillation step raised purity standards three years ago—something we implemented after a key partner requested tighter controls on chlorinated byproducts. Adjusting the storage tank linings, following feedback about possible trace metallic leaching, extended shelf stability and reduced color drift over time. Every change grows from active engagement: our partners speak, we adapt, and both sides reduce risks and boost returns.

    We offer technical guidance not just on product performance but on setup logistics. A major customer moved to larger bulk tanks last year; we consulted on insulation needs, dehumidification strategies, and siphoning procedures that minimize fluid losses. Rather than setting and forgetting, we keep lines of communication open. Batch failures, if they ever occur, prompt root cause analysis from our own chemists, who replicate client procedures in our pilot facility, aiming for direct and practical solutions instead of lengthy reports filled with theory.

    As interest grows in green chemistry, we have experimented with recycling schemes for chlorinated intermediates. Some progress remains incremental, but close work with solvent recovery vendors points to less waste, fewer emissions, and a tighter loop between synthesis and disposal. Because we control the process end-to-end, we can partner quickly on custom purification or eco-friendly packaging trials—a flexibility that impersonal traders or generic suppliers often lack.

    Building Confidence Through Expertise and Traceability

    Every operator in our facility—from the cell house through final packaging—understands what it means to manufacture a product that impacts dozens of industries. We invest in staff training at every level, so nobody labors under uncertainty when issues arise. Because we produce the material ourselves, we handle raw intermediate concerns, impurity troubleshooting, and logistics bottlenecks directly. Our experience tells us that this boots-on-the-ground familiarity gives customers a direct line to answers that matter.

    Over years of working with Isopropyl 2-Chloropropionate, we have learned that product quality is set early—during synthesis, not after. Attention to detail drives every step, from incoming raw material testing to the protocols our shift chemists use for waste capture and neutralization. We keep a “lessons learned” log open to all technical staff, where issues and smart fixes join a living institutional memory. More than a few cost-saving tweaks, safer handling practices, and proof-of-concept process shortcuts have come out of this direct reflection.

    Trust grows when your clients see transparent operations and professional pride. Direct visits, documentation access, and open dialogue nurture relationships that weather market shocks or project delays. That long-term perspective informs every shipment and system upgrade.

    Partnership for the Long Game

    Our team sees Isopropyl 2-Chloropropionate as more than another specialty intermediate—it represents how thoughtful manufacturing and steady dialogue can build real value. Projects can arise unexpectedly—a late-stage process change, an urgent scale-up for a new customer, or a troubleshooting marathon to fix a recurring side reaction. With in-house production, we answer quickly: adjusting production rates, running custom purity grades, or sharing technical knowledge won through daily practice.

    We remember our early days, running trial batches in aging vessels, and every improvement since has been shaped by direct experience. Larger units, modular distillation trains, fine-tuned process analytics—each addition started with a challenge from the field and grew into an upgrade. Our work with Isopropyl 2-Chloropropionate continues to evolve, guided by client needs and our own pursuit of better, safer, and more consistent chemistry.

    Effective solutions grow from experience and careful investment at every stage. We invite partners to collaborate, not just order, drawing on the full value of a supplier with manufacturing know-how, advanced analytical resources, and a commitment to continuous improvement. That promise sits at the core of everything we do with Isopropyl 2-Chloropropionate—and with every batch, we back it with knowledge born from years of manufacturing, hands-on troubleshooting, and genuine teamwork.