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Isobutyl Formate

    • Product Name Isobutyl Formate
    • Alias Formic acid, isobutyl ester
    • Einecs 203-746-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    966632

    Chemical_Name Isobutyl Formate
    CAS_Number 542-55-2
    Molecular_Formula C5H10O2
    Molecular_Weight 102.13 g/mol
    Appearance Colorless liquid
    Odor Fruity, rum-like odor
    Boiling_Point 89-90 °C
    Melting_Point -90 °C
    Density 0.878 g/cm³ at 20 °C
    Flash_Point 7 °C (closed cup)
    Solubility_in_Water Slightly soluble
    Vapor_Pressure 110 mmHg at 25 °C

    As an accredited Isobutyl Formate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Isobutyl Formate is packaged in a 25-liter blue HDPE drum with a secure screw cap, featuring clear hazard labeling.
    Shipping Isobutyl Formate is shipped as a flammable liquid under UN No. 1987, Class 3, Packing Group III. It must be stored in tightly sealed containers, kept cool, and away from ignition sources. Handling requires compliance with transport regulations for hazardous chemicals, using appropriate labeling, and ensuring proper ventilation during shipping.
    Storage Isobutyl Formate should be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Keep containers tightly sealed and clearly labeled. Avoid exposure to direct sunlight and incompatible substances like strong oxidizers. Use appropriate, chemical-resistant storage containers and ground all equipment to prevent static discharge. Follow all local regulations for flammable liquid storage.
    Application of Isobutyl Formate

    Applications of Isobutyl Formate in Industrial Manufacturing

    Isobutyl formate plays a defined role in several mass manufacturing sectors as an industry-grade ester solvent and synthetic intermediate. Our experience as a direct producer supports downstream customers through technical compatibility, consistent quality, and regulatory awareness across all prominent application segments.

    1. Flavors and Fragrances Synthesis

    Manufacturers use isobutyl formate as an aroma ingredient and as a synthesis intermediate when developing compounded flavors, especially in fruity, apple-pear, and rum-type profiles. The ester imparts a sweet, volatile note, and its volatility allows rapid dispersion in perfumery compositions and flavor bases. In flavor-compounding houses, qualified teams formulate it within the scope of food-grade and fragrance-grade requirements, always referencing sensory thresholds and toxicological data. The handling and blending process requires established air handling and storage protocols due to the material’s volatility and odor impact.

    Industry compliance standards

    • Food Chemicals Codex (FCC) for flavor additives
    • IFRA Standards (International Fragrance Association)
    • European Regulation (EC) No 1334/2008 on flavorings
    • U.S. FEMA GRAS status (No. 2225) for flavor use

    Typical usage ratio

    • 0.1‒10 ppm in finished beverage or food flavors
    • 0.01‒0.5% in compounded fragrance bases, adjusted for IFRA limits and sensory thresholds

    Downstream process integration

    • Direct dosing into blending tanks during flavor or fragrance compounding
    • Control addition prior to emulsion or encapsulation phases
    • Pre-mixing for alcohol-based and oil-based formulations
    • Controlled transfer via nitrogen blanketed systems due to volatility

    Final product types

    • Fruit and dairy flavor formulations for beverages and confectionery
    • Scented body sprays, EDT, EDP, and personal care fragrances
    • Household air fresheners
    • Flavored syrups and liquid food aromas

    2. Industrial Solvent for Coatings and Printing Inks

    The manufacturing sector uses isobutyl formate as an active solvent in nitrocellulose-based lacquers, inks, and industrial coatings where a fast-evaporating, medium-polarity solvent enhances pigment wetting and film leveling. The ester’s solvency accelerates drying while minimizing orange peel defects. Quality assurance teams check its purity and water content before dosage, ensuring compatibility with resin systems and compliance with worker safety regulations in large-scale blending and solvent recovery setups.

    Industry compliance standards

    • EU REACH registration for industrial solvent use
    • OSHA 29 CFR 1910.1200 (Hazard Communication Standard)
    • ISO 9001:2015 Quality Management Systems (for manufacturing audits)
    • Directive 1999/13/EC (VOC in paints and varnishes)

    Typical usage ratio

    • 5–20% by weight in nitrocellulose lacquer systems and printing inks
    • 2–10% in automotive touch-up paints, adjusted for evaporation rate requirements

    Downstream process integration

    • Metered solvent addition after pigment and resin dispersion
    • Inline blending during ink manufacturing
    • Evaporation-controlled environments in filling lines
    • Quality testing for haze and flow prior to packaging

    Final product types

    • Nitrocellulose wood lacquers
    • Plastic coatings for appliance housings
    • Flexographic and gravure printing inks
    • Touch-up spray paints for industry or retail

    3. Pharmaceutical Intermediate Synthesis

    In pharmaceutical technical synthesis, isobutyl formate operates as a building block in multi-step production of complex organic intermediates, especially as a selective alkylation or acylation agent in esterification and transesterification reactions. Process chemists follow GMP practices and strict material traceability, ensuring batch release adheres to pharmacopeial purity targets for downstream processing into regulated APIs or intermediates. Integration occurs in controlled reactors with validated cleaning, verifying absence of cross-contaminants.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 210/211 (manufacturing and quality control of drugs)
    • European Pharmacopoeia (Ph. Eur.) — relevant for process chemicals
    • ISO 15378:2017 (Primary packaging for pharmaceuticals)

    Typical usage ratio

    • 10–50 mol% relative to target intermediate in esterification protocols
    • Adjusted according to yield optimization based on in-process analytics

    Downstream process integration

    • Dosed into jacketed glass-lined reactors at fixed charge levels
    • Employed in acylation stages, sometimes as a solvent or reactant
    • Recovered by distillation for purity recycling where allowable
    • Accompanied by strict waste and solvent recovery procedures

    Final product types

    • Active pharmaceutical ingredient intermediates
    • Chiral building blocks for drug discovery
    • Specialized ester and amide intermediates
    • Contract manufactured pharmaceutical raw materials

    4. Agrochemical Synthesis and Formulations

    Agrochemical formulators and upstream synthesis teams use isobutyl formate as a mild esterification agent and carrier solvent in the production of selective herbicide and insecticide intermediates. The compound supports precise molecular conversions needed for high-purity active ingredient production. Batch records strictly monitor the input amount and process routing to maintain agrochemical registration compliance. Technical staff validate solvent residuals before packing into formulated pre-mixes for downstream dilution or encapsulation.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • REACH and CLP Regulation (EC) No 1272/2008 for agrochemical intermediates
    • OECD Guidelines for the Testing of Chemicals
    • ISO 14001:2015 (Environmental Management)

    Typical usage ratio

    • 5–30% in reaction mixtures for synthetic intermediates
    • 0.5–10% in formulated carrier systems based on solubility properties

    Downstream process integration

    • Metered batch dosing into reaction vessels at controlled temperatures
    • Post-reaction separation and solvent stripping under vacuum
    • Direct blending into EC (emulsifiable concentrate) formulations
    • Residue analysis by GC for process control and compliance prior to release

    Final product types

    • Active ingredient intermediates for selective herbicides
    • Formulated EC and SC pesticide concentrates
    • Accelerated synthesis of insecticidal building blocks
    • Adjuvant premixes for large-scale field applications

    5. Chemical Intermediate in Fine Chemical Synthesis

    Producers of specialty chemicals and fine chemicals adopt isobutyl formate as a reactivity-tunable intermediate in esterification and transesterification protocols aimed at manufacturing custom esters, high-purity aldehydes, and high-value specialty solvents. Laboratory-scale and production systems adjust processing for target reactivity, with material addition monitored for reaction temperature and by-product minimization. Detailed process documentation supports downstream traceability and analysis.

    Industry compliance standards

    • ISO 9001:2015 (Production process management)
    • Responsible Care® Management System
    • REACH-compliant Safety Data Sheets
    • Custom documentation as per customer NDA and specification requests

    Typical usage ratio

    • 5–35% as an active reagent in fine chemical synthesis cycles
    • Process ratio fixed relative to other feedstocks and targeted yield profiles

    Downstream process integration

    • Fed batch-wise into stirred tank reactors at specified points
    • Participates in controlled ester-exchange or hydrolysis steps
    • Isolation of target ester via fractional distillation on completion
    • Recycling unreacted ester into continuous process streams

    Final product types

    • High-purity specialty esters for electronics and surface treatment
    • Fine aldehydes and formates for analytical and R&D use
    • Custom intermediates for contract chemical synthesis
    • Test reagents and analytical standards
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    Certification & Compliance
    More Introduction

    Exploring Isobutyl Formate from a Manufacturer’s Perspective

    Everyday Insights from the Plant Floor

    Our team has worked hands-on with isobutyl formate for years, and nothing convinces you of its value quite as much as seeing it move from reactor to storage, and on to our clients. Daily operations at a chemical manufacturing site reveal what the paperwork sometimes misses: how tight control over purity, and process adjustments, make a real difference. In short, manufacturing isobutyl formate means sweating the small details and knowing what sets a good batch apart.

    Produced as a clear, colorless liquid with a fresh, fruity odor, isobutyl formate (CAS No. 542-55-2) supplies a precise interpretation of where efficiency meets opportunity in specialty chemicals. Factories cannot afford to waste time. They need reliable solvents and intermediates that slot into their process with consistent results. On our lines, we follow close monitoring protocols and in-line analysis for texture, composition, and moisture content at each stage. Working closely with R&D and production chemists, I see the focus is never just on yield; it’s on building a product that meets user expectations with every drum, every tanker, every single delivery.

    Why the Specifications Matter

    We stick to specifications that we know matter to practical users. Purity levels are not decorative numbers — our batches regularly test above 99.5% by GC, and we set water content below 0.1%. This tight threshold improves shelf life and performance when clients use the material in fine fragrance mixes, flavors, or flexible coatings. As lifetime plant workers know, the margin between 98% and 99.5% can matter when reductions, extractions, or blends need predictable outcomes. Clients running electronic component lines, who use our isobutyl formate in specialty detergents or as a controlled solvent, depend on this attention to detail. If we cut corners, their processes suffer. We’d hear about it, and not just once.

    Packing it right is production. We use steel drums, IBCs, and tankers with strict line-cleaning between grades to rule out cross-contamination. You notice when the drum’s lining fails and a faint taint creeps into the next container. Our plant team knows how these details save headaches down the road, so we set protocols that technicians actually follow. These aren’t academic specifications — these are real-world habits that protect the quality of every ton.

    Meeting Real Demands in Industry

    Isobutyl formate always finds a spot in sectors willing to innovate. It acts as a low-density solvent and a fruity-note carrier in flavor and fragrance work. In paints and surface coatings, it flashes quickly without leaving heavy residues. Production runs using high-purity isobutyl formate lead to stable dispersions in specialty inks and polishes. The professionals in these industries drive us to continually fine-tune our batches — whether that means true-to-spec odor profiles or guaranteeing storage stability for months at a time.

    Talking to field engineers who run extraction columns or work with chromatographic separations highlights why a predictable, tightly-batched solvent matters. Small inconsistencies in one drum ripple out as unpredictable performance on the job. In flavorhouses and fragrance labs, even a slight off-note can waste hours of blending or ruin entire tester series. That’s how the plant stays accountable.

    How Isobutyl Formate Differs from Other Esters

    Years of experience with multiple esters on a busy manifold illustrate that isobutyl formate sits in a distinctive niche. Compare it to n-butyl formate or ethyl formate: you quickly see the differences. Isobutyl formate has a unique balance — enough volatility for rapid evaporation, but not as aggressive or sharp as ethyl formate. Its lower density and higher boiling range compared to methyl or ethyl analogs let it substitute effectively where regulation or user application eliminates some faster or harsher solvents.

    Perfume and aroma formulation chemists know isobutyl formate lends a smooth, crisp top note, less piercing than propyl formate and not so fleeting as methyl or ethyl types. This difference means more than laboratory numbers. We see it each time our contacts in flavor and fragrance houses return for repeat runs, asking for the same “batch feel”. Cost-wise, it lands in the right spot—not too exotic for wide-ranging everyday solvents but specialty enough for boutique blends.

    Industrial engineers in coatings often comment on the better balance of drying time versus workability. Unlike some higher esters, isobutyl formate doesn’t introduce sticky residues or interfere with binder systems in waterborne paints. We see requests for comparison samples — users often line up isobutyl, n-butyl, and propyl esters side by side and judge for themselves in coating trays or sample panels—the smooth, light finish tells the story.

    For those handling process scale-ups, isobutyl formate offers advantages in vapor pressure and solubility compared with both lighter and heavier esters, which shapes everything from storage guidelines to workplace safety planning. Our safety coordinators note that lower flammability and regulated odor thresholds help meet both regulatory and health targets, with practical measures in established workflows.

    Learning from the Market and the Plant Floor

    Throughout my years in this business, clients quickly signal their preferences through repeat orders. While some come chasing price, the majority return because quality drives their results. We listen to user feedback constantly — it’s direct, sometimes blunt, and not always what we expect. They want drums to pour cleanly. They worry about residue. They spot tiny changes in aroma, haze, or reaction pace, sometimes before the data confirms what’s off.

    This feedback guides every plant meeting and batch protocol update. As regulatory requirements grow tighter, the cost of non-compliance or sub-par specs climbs as well. We see greater demand from manufacturers moving to lower-toxicity, lower-smog precurors, and safer raw materials. Isobutyl formate fits this trend — helping formulators replace older, more hazardous formates, but without sacrificing performance. That isn’t theory: it’s direct from shop-floor teams and regulatory compliance audits, who push us to publish clear specifications and hold our product to them week after week.

    Logistics specialists on our team find that isobutyl formate transports safely, but always recommend secondary containment and tight seals. The odor, while not offensive, can be strong in enclosed spaces, so we move it in well-maintained tanks and ask logistics partners to brief drivers and handlers routinely. Surface stains, leaks, or odor clouding are rare if containers meet basic maintenance — a testament to better handling. Our site’s maintenance logs track tank and pump life to minimize downtime, since quality suffers if equipment runs dirty or on the edge.

    Applications Growing with Industry Needs

    We’ve watched use cases for isobutyl formate grow over the decades. Flexible coatings, automotive underlays, and even environmental analysis labs have reached out for specialty runs. Its solvency range crosses between polar and slightly nonpolar solutes, which helps R&D teams solve stubborn formulation issues. Our staff have sat through hundreds of formulation planning meetings where a switch to isobutyl formate solved sticking points—literally and figuratively.

    In flavor and fragrance, its unique top-note character translates to bottled freshness in beverages, confections, and bakery flavors. Perfumers exploit its volatility to build quick-lifting notes that don’t fade instantly. At several client workshops, we’ve learned how even minor shifts in purity or residual acid content affect the stability and impact of the final product. Our QC manager keeps a running chart of off-odor triggers and tells teams to flag even faint sweetness or staleness that signals trouble ahead.

    Newer uses keep emerging. Some clients blend isobutyl formate into fuel markers or specialty tracing chemicals, citing the natural odor and evaporative profile. Agricultural sector users look for custom-grade formates as adjuvants or process enhancers—often asking us for sample runs or modified specs to cope with crop residues or environmental conditions. We’re seeing more fine-tuning on request: separated distillation fractions, customized odor intensity, and even test batches for green chemistry platforms. This drives our team to experiment with small-batch and pilot-scale reactors, building flexibility into a process often known for rigidity.

    Quality as a Shared Commitment

    It’s tempting to see products like isobutyl formate just as solvents or bulk items on an inventory sheet. Working at the source shows a larger story. Purity controls, process tweaks, and continual dialogue with researchers and buyers shape each run we make. Our clients talk openly about project wins and failures — we hear the full spectrum, which keeps plant teams grounded in real-world impact.

    We know one batch can’t please every application. Sometimes a user needs a drier, purer material for chromatography or electronics. Sometimes a flavor maker asks for a warmer, rounder odor profile. Our development chemists document root causes and obsessively sample each shift, making sure the final product stands up to multiple real-world checks. Tracking every shipment, we see patterns — which specs lead to complaints and which drive compliments. This loop closes only with transparency, hands-on checks, and trust built batch by batch.

    Emergencies sharpen focus. If something drifts from spec, we catch it quickly: on the fill line, in the shipping bay, or after feedback from a loyal customer. Action means pulling suspect product before a client ever sees it, rerouting supply, and updating process as soon as trouble appears. Each episode becomes a learning moment — not just for operators, but for management, who deal directly with consequences. Our best improvements started with plant-floor advice and client calls, not with paperwork or marketing theory.

    Environmental and Regulatory Considerations

    Modern manufacturing faces sharper scrutiny each year. Users and regulators expect formates to fit into green chemistry profiles and minimize environmental impact from production to final disposal. As raw material prices shift and supply dynamics tighten, our plant explores recycled content, lower-energy process cycles, and waste minimization on every production campaign. We have seen a steady shift in requests for isobutyl formate meeting not only REACH or TSCA registration, but also voluntary standards declaring reduced carbon footprint or lower toxicity-by-products.

    Our environmental engineers measure VOC impacts, look for cut-back emissions, and model worst-case spill scenarios. These aren’t just theoretical models — we’ve cleaned up minor leaks enough times to know why procedures have to be more than policy. Local communities want transparency, and we’ve found that open lines, published audit summaries, and plant tours build trust. Sometimes our efforts uncover energy savings or waste reductions that directly benefit our bottom line, or let us keep price stability for long-term customers.

    Clients depend on us to respect restrictions on hazardous air pollutants, report usage accurately, and provide complete batch traceability. In return, they share research on new applications — from electronic cleaning to next-gen polymers — that keep us close to the cutting edge. Each new use comes with tighter specs or reporting targets, and our teams stay sharp by responding quickly to audit requests or compliance changes. Isobutyl formate remains a flexible workhorse, but one that lives under a spotlight as regulatory expectations rise.

    Supply, Scalability, and the Lessons from Disruption

    Plant teams know the real meaning of supply chain “flexibility” — it means hunting down missing drums, switching raw suppliers, and rerunning lines in overtime to make deadlines stick. During supply disruptions, we’ve pulled senior techs off other projects to ramp up isobutyl formate, confident the process holds up to sudden scaling. Our leadership learned to diversify raw material streams so we dodge most upstream volatility, never betting on a single-point-of-failure.

    When energy markets jump, so do production costs. We’ve invested in monitoring and automation to spot efficiency drifts, tune batch timing, and capture more yield from the same inputs. Our teams walk the line daily, checking valves, scanning temperature readouts, and tuning reaction parameters in real time, not waiting for distant lab confirmation. This boots-on-the-ground agility keeps us shipping even as schedules lurch. We share process tweaks in tight loops across daily standups, tweaking in response to new market realities and keeping customers informed of what’s happening on the ground.

    Our logistics team built relationships with specialized carriers who understand chemical hazards and the quirks of moving isobutyl formate across borders. They stay in close touch with customs and transport regulators, banking on transparent paperwork and on-the-spot troubleshooting. When a shipment runs late or changes routing, hands-on tracking and clear communication make the difference between an inconvenience and a crisis. Years of direct work on the dock and in the warehouse trained us to keep backups ready, and never assume a steady state.

    What’s Next for Isobutyl Formate?

    The next chapter for isobutyl formate will unfold where industry demand meets regulatory and consumer priorities. Researchers look for safer, better-performing esters, and our job as manufacturers means keeping our process a step ahead. We plan new pilot reactors and greener process chemistry to meet both upcoming regulations and evolving customer requests. We anticipate more niche fragrance, bio-based, and regulatory-driven programs, and our pilot team builds small-scale flexibility for on-demand runs.

    Upstream, we’re qualifying new sustainable feed sources, retraining operators and maintenance staff, and beta-testing real-time process monitoring hardware. Downstream, close coordination with flavor, fragrance, and specialty chemical users keeps us anchored in what really matters — reliability, transparency, and practical quality over years, not just in marketing cycles. We don’t see isobutyl formate disappearing from formulators’ toolboxes any time soon. Instead, we see its role continue to evolve, shaped by the needs and expectations of those whose success depends on the details.

    Our experience tells us that user feedback and plant discipline shape the ultimate value of chemical products. In and outside the plant gates, honest communication, adaptability, and real commitment to spec in every batch drive not only continued business but also the long trust between manufacturer and user. That trust takes years to build, but only a single missed shipment or substandard batch to lose.

    Closing Thoughts — Experience that Delivers

    The story of isobutyl formate as we see it is not abstract. It’s a story lived daily on the production line, in the QC lab, on the road to customers, and in the meeting rooms where formulations come together. We’re proud of our track record, built not by perfect paper processes, but by teams who care about what actually gets delivered, and by partnerships with people who count on us to keep quality and reliability steady for projects yet to be imagined. Together, we continue to refine not just the product, but the relationships and processes that let industry do more, responsibly and with confidence.