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Hydrogen Chloride [Anhydrous]

    • Product Name Hydrogen Chloride [Anhydrous]
    • Alias Hydrochloric acid (anhydrous hydrogen chloride)
    • Einecs 231-595-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    668525

    Chemical Name Hydrogen Chloride
    Synonyms Anhydrous Hydrogen Chloride, HCl gas
    Molecular Formula HCl
    Molecular Weight 36.46 g/mol
    Cas Number 7647-01-0
    Appearance Colorless gas
    Odor Pungent, irritating
    Boiling Point -85.05°C
    Melting Point -114.2°C
    Solubility In Water Freely soluble
    Density 1.49 g/L (at 0°C, 1 atm)
    Vapor Pressure 40 atm (at 21.1°C)

    As an accredited Hydrogen Chloride [Anhydrous] factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Hydrogen Chloride [Anhydrous], 500g, is packaged in a corrosion-resistant, sealed steel cylinder with clear hazard labeling and safety instructions.
    Shipping Hydrogen Chloride [Anhydrous] is shipped as a compressed, liquefied gas in high-pressure steel cylinders or tank cars. It requires secure, upright storage with proper ventilation. Shipping must comply with regulations for hazardous materials due to its corrosive and toxic nature. Use appropriate hazard labels and emergency response information during transport.
    Storage Hydrogen Chloride [Anhydrous] should be stored in tightly sealed, corrosion-resistant containers, such as steel cylinders, in a cool, dry, and well-ventilated area, away from moisture and incompatible substances. Storage areas should be equipped for leak detection and contain proper ventilation. Keep away from heat sources, direct sunlight, and combustible materials, and ensure ready access to emergency equipment and eyewash stations.
    Application of Hydrogen Chloride [Anhydrous]

    Applications of Hydrogen Chloride [Anhydrous] in Industrial Manufacturing

    Hydrogen chloride (anhydrous) enables crucial chemical transformations in multiple industrial sectors. As a manufacturer, we supply high-purity hydrogen chloride for core synthesis and processing operations. The following sections detail key application scenarios, practical handling, and finished product segments based on direct integration by global producers.

    1. Pharmaceutical Grade Hydrochlorides Production

    Pharmaceutical intermediates and finished drugs frequently require hydrochloride salts for improved solubility and stability. Direct gas-phase or anhydrous hydrogen chloride introduction secures precise salt formation in active pharmaceutical ingredient (API) reactors. Process control prevents water incorporation, ensuring no unwanted hydrolysis or impurity formation. Manufacturers adopt validated systems for batch or continuous acid gas dosing, with extremely tight control over gas-phase presence. Final APIs and advanced intermediates undergo extensive quality assurance, including residual chloride and moisture assays, per pharmacopeial specifications.

    Industry compliance standards

    • United States Pharmacopeia (USP)
    • European Pharmacopoeia (Ph. Eur.)
    • Japan Pharmacopoeia (JP)
    • Good Manufacturing Practice (GMP, ICH Q7)

    Typical usage ratio

    • 0.8 – 1.2 molar equivalents of hydrogen chloride per mole of amine or base functional group, adjusted per API solubility and salt-forming requirements.

    Downstream process integration

    • Direct introduction at the amine neutralization step, employed in jacketed reactors or gas-liquid contactors.
    • Condensed HCl vapor or controlled in situ gas introduction.

    Final product types

    • API hydrochloride salts (e.g., sertraline hydrochloride, loratadine hydrochloride)
    • Pharmaceutical intermediates with hydrochloride stabilization
    • Injectable and oral solid dosage forms incorporating specific hydrochloride APIs

    2. Vinyl Chloride Monomer (VCM) Synthesis

    The production of vinyl chloride monomer depends on precise reaction of anhydrous hydrogen chloride with acetylene. This step forms the building block for polyvinyl chloride (PVC) polymers. The process typically involves a mercuric chloride catalyst, requiring consistent hydrogen chloride feed and rigorous emissions controls. Plants integrate dedicated hydrochloride storage, vapor handling, absorption, and process gas purification to meet polymer-grade requirements. All gas-phase reactant flows undergo real-time monitoring linked to product purity testing.

    Industry compliance standards

    • Occupational Safety and Health Administration (OSHA) 29 CFR 1910.1017 for VCM exposure
    • American Society for Testing and Materials (ASTM D1665 for HCl purity and analysis)
    • REACH registration for intermediates
    • ISO 9001 for process management

    Typical usage ratio

    • Approximately 1.1 – 1.2 metric tons of hydrogen chloride per metric ton of acetylene, adjusted to maintain slight HCl excess and minimize byproduct formation.

    Downstream process integration

    • HCl is introduced at the main acetylene hydrochlorination reactor inlet.
    • Continuous gas-phase mixing, with closed-loop control to reactor temperature and pressure.

    Final product types

    • Vinyl chloride monomer (VCM) for PVC manufacture
    • Suspension and emulsion-grade polyvinyl chloride resins

    3. Electronic-Grade Metal Surface Treatment

    Semiconductor device and printed circuit board manufacturers utilize anhydrous hydrogen chloride for selective etching and cleaning of silicon and metallic surfaces. The absence of water is critical to prevent uncontrolled corrosion and maintain surface uniformity. Systems use ultra-high purity piping and scrubbing for process gas. Strict controls remove any metallic or particulate contamination to satisfy electronics fabrication specifications. Integration takes place in preprocessing and wafer cleaning steps, followed by rigorous rinse and purity verification.

    Industry compliance standards

    • SEMI C64 for electronic-grade hydrogen chloride
    • IPC-A-600 for PCB standards
    • ISO 14001: Environmental management for emissions controls
    • RoHS (Restriction of Hazardous Substances) compliance

    Typical usage ratio

    • Process gas flow rates of 1–10 Standard Liters per Minute (SLM), adjusted per etching area and stage duration, based on substrate size and purity class.

    Downstream process integration

    • Etching and cleaning modules prior to epitaxy and metallization stages.
    • Wafer batch or inline processing in cleanroom environments.

    Final product types

    • Semiconductor wafers
    • Printed circuit boards (high-reliability and fine-line)
    • MEMS components

    4. Synthetic Dye and Pigment Manufacturing

    Large-scale producers of azo dyes, phthalocyanine pigments, and triphenylmethane colorants employ hydrogen chloride in coupling, diazotization, and precipitation steps. The gas is introduced to form soluble dye salts or as a catalyst for ring closures, often at elevated temperatures. Agitation and off-gas treatment are essential to maintain color purity and yield while complying with regulatory emissions limits. Quality management ensures minimized iron and metal ion contamination arising from contact equipment, critical for consistent product hue.

    Industry compliance standards

    • OEKO-TEX Standard 100 for textiles
    • EN 71-3 for pigments in toys
    • REACH registration for dye intermediates
    • ISO 9001 for quality assurance processes

    Typical usage ratio

    • 0.5 – 1.5 equivalents relative to aromatic amines or coupling agents, with range adjusted for target intensity and base load in continuous runs.

    Downstream process integration

    • Controlled addition before dye coupling or pigment precipitation reactors, with local HCl vapor handling and absorption towers.

    Final product types

    • Textile dyes (acid, direct, reactive dyes)
    • Printing inks
    • Organic pigments for coatings and plastics

    5. Specialty Alkyl Chloride Synthesis for Agrochemicals

    Hydrogen chloride serves as a primary chlorinating agent for manufacturing methyl chloride, ethyl chloride, and higher alkyl chlorides used as agrochemical intermediates. Closed reactors introduce the anhydrous gas to ensure high conversion and minimal by-product formation. Strict in-process quality controls monitor chlorine incorporation rates and residual gas. Integration with downstream neutralization and distillation units ensures product stability prior to use in synthesis of active crop protection agents and intermediates.

    Industry compliance standards

    • FAO/WHO technical material specifications for agrochemicals
    • ISO 17025 for laboratory testing and QC validation
    • REACH registration for agrochemical intermediates
    • Responsible Care (chemical manufacturing stewardship initiative)

    Typical usage ratio

    • Anhydrous gas charged at 10–20% molar excess relative to alkanol or alkene refractant, tailored to specific product and process yield targets.

    Downstream process integration

    • Inline introduction in batch or semi-batch reactors, followed by downstream gas-liquid separation and neutralization.

    Final product types

    • Methyl chloride, ethyl chloride
    • Intermediate alkyl chlorides for herbicide and pesticide synthesis
    • Certain pre-emergent and post-emergent agrochemical formulations

    6. Polyurethane and Polyisocyanurate Foam Production

    Anhydrous hydrogen chloride acts as a chain terminator and stabilizer in selected isocyanate manufacturing routes for rigid polyurethane and polyisocyanurate foams. It reacts at defined points with excess isocyanate to control viscosity, molecular weight, and reactivity, promoting desired foam structure in downstream formulations. Manufacturing plants employ closed-system storage, process metering, and emission treatment according to occupational exposure limits and plant safety requirements. Finished foam materials undergo emissions and reactivity testing to validate compliance with regional end-use standards.

    Industry compliance standards

    • ASTM D3574 for flexible and rigid polyurethane foam properties
    • ISO 9001 and ISO 14001 for process and environmental controls
    • EN 13165 and EN 14315 for insulation foam materials
    • OSHA regulations for workplace exposure

    Typical usage ratio

    • 0.1 – 0.3 parts hydrogen chloride per 100 parts isocyanate, adjusted in pilot trials for target foam properties and process throughput.

    Downstream process integration

    • Controlled addition during pre-polymer mixing before foam expansion and curing stages.

    Final product types

    • Rigid and semi-rigid polyurethane panels
    • Spray-applied polyisocyanurate insulation foams
    • Automotive and appliance insulation components
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    Certification & Compliance
    More Introduction

    Hydrogen Chloride Anhydrous: Our Experience from the Factory Floor

    Producing Hydrogen Chloride Anhydrous: Why Purity and Process Matter

    Every tank and cylinder of hydrogen chloride anhydrous leaving our plant reflects years honing processes and solving real problems. We understand the realities inside the production unit—purity here isn’t just a number. It shapes the actual results for glass etchers, pharmaceuticals, electronics, and dyes. Our focus on anhydrous grades begins at the heart of synthesis, using pure raw hydrogen and high-grade chlorine, carefully reacting them under controlled thermal conditions. Rigorous drying steps follow. Water turns hydrogen chloride into troublesome hydrochloric acid, destroying much of its usefulness in precise reactions, so we chase down every trace of moisture. Our typical production achieves 99.99% purity as measured by advanced gas analysis, and we lean on constant calibration and sample verification because this level of quality doesn’t maintain itself.

    Model and Specifications: Built for Demanding Applications

    Industrial hydrogen chloride comes in many guises. We recognize the difference between chemistry lab material and bulk volumes for multinational manufacturers. Our flagship HCl anhydrous model, designated HCl-GAS99, arrives rigorously compressed in seamless steel cylinders from 5kg to 800kg, capable of withstanding high-pressure loads due to internally passivated surfaces. Valves originate from corrosion-resistant alloy to eliminate contamination risk. Each batch comes documented down to certificate-of-analysis–including trace metallics, non-volatile impurities, and moisture content. There are no ambiguous claims of “industrial grade” here. We tailor specifications to customer needs for electronics- or pharmaceutical-grade hydrogen chloride. Electronics-grade product often calls for purity beyond 99.999%, especially where etch rates and surface consistency depend on total absence of alkali metals and heavy metals, while pharmaceutical synthesis generally tolerates 99.99% with full traceability for regulatory compliance.

    The Critical Role of Anhydrous Hydrogen Chloride in Today’s Industry

    In our plant, we see how downstream users in many sectors rely on genuinely anhydrous hydrogen chloride, especially those working with sensitive chemistry. Semiconductor companies etch silicon wafers in complex patterning steps, using HCl to clean oxide layers and remove metallic residues. Even a small drop in purity translates directly into failed yields or unstable characteristics in finished chips. We remember one client’s entire plasma-etch line stalling—trace moisture in a shipment of what looked like clean HCl was causing catastrophic short circuits on thin film layers. The solution wasn’t just better packaging; it required reviewing cleaning procedures up and down the logistics chain. The lesson stayed with us: every chemical is only as good as what’s in it and what isn’t.

    In organic synthesis, careful addition of anhydrous hydrogen chloride to organics opens doors to reactions impossible with aqueous HCl. Alkyl chlorides, specialty pharmaceuticals, and polymers often depend on gas-phase HCl, introduced with metered accuracy to avoid side reactions caused by water. Customers in advanced polymerization and rubber modification run lines where a mist of HCl anhydrous provides the necessary catalyst or functional group, with plant operators watching moisture monitors like hawks. If we slacken our standards, their runs produce weak or off-spec material—this isn’t abstract to us; we hear about it immediately.

    Hydrogen Chloride Anhydrous vs. Other Forms: Why Dryness Makes the Difference

    Hydrogen chloride comes in both aqueous and anhydrous forms, and the market treats them very differently. Many suppliers push hydrochloric acid, a water solution of hydrogen chloride at various concentrations. For cleaning, pickling steel, or neutralizing bases, hydrochloric acid does the job at low cost. In contrast, only strictly anhydrous gas offers the directness required in dry, water-sensitive applications. A common misconception is that one can simply evaporate or distill aqueous acid to get anhydrous gas—this process produces water vapor and results in low-purity output, not suitable for electronics or pharma fields. True anhydrous hydrogen chloride is produced without water ever mixing into the process. Our experience reinforces: gas-phase HCl interacts quite differently with substrates and chemical feedstocks. For certain synthetic chemistries, water as a contaminant retards yields or even halts progress. Our technical team fields questions weekly from researchers and manufacturers struggling with inconsistent reaction profiles after unknowingly introducing watery acid instead of dry HCl gas. The solution: educate at every step, support clients with technical facts, supply product with verifiable dryness.

    Using our HCl Gas: Practical Experience from Our Largest Clients

    In glass manufacturing and etching, HCl gas forms volatile silicon chlorides, vaporizing residues off glassware or integrated circuits. Plant engineers rely on the consistency of our gas, knowing batch-to-batch variability is a recipe for defects or downtime. Typical usage calls for flow-controlled introduction through corrosion-resistant glass or PTFE piping, routed straight from high-pressure storage to reactor heads. We maintain partnerships with valve manufacturers to ensure every delivery system matches our standards, because any leak, impurity, or backpressure jump can set off months of troubleshooting. This direct feedback shapes our work every day.

    We’ve worked with dye and pigment manufacturers scaling up Friedel-Crafts alkylation, where gas-phase HCl often acts as both a reactant and a pH regulator. Incorrect control of gas flow, or introducing trace moisture, can spoil expensive feedstock. Our engineers consult on installations upstream of reactors, examining pressure regulation and moisture traps in real-world conditions, not just from the lab bench. Stories abound of line blockages cleared only after isolating condensate from inferior HCl gas supplies. Each time, robust drying, filtration, and real-time sampling made the difference. When performance matters in real production, it pays to buy from the plant that’s lived through these challenges, not from a broker or a warehouse.

    Safety, Packaging, and Handling: Lessons Earned the Hard Way

    Working on the manufacturing side, we know that safety and handling for anhydrous hydrogen chloride are never afterthoughts. The gas is highly corrosive and dangerous to inhale, so our filling operations run inside vented containment covers with routine sensor monitoring. Years back, after one incident involving valve corrosion, we switched entirely to custom-fabricated, non-reactive alloys for all in-contact surfaces. Cylinders move from production to filling lines and then to certified pressure testing at each load, not every few cycles. These procedures aren’t about ticking boxes—they shield both our crews and the end user.

    We take pains to educate clients on storage, specifying cylinder orientation, required temperature ranges, and transport logistics under local regulations. Distributors sometimes cut corners after receiving product, stacking tanks double-deep or failing to check for static discharge controls. Our direct ship-to-user model, with detailed handover and inspection at delivery, drastically cut down on complaints and lost gas due to leaks or regulator sabotage. These commitments grew from field experience, not from reading guidelines or regulatory bulletins. We gained new respect for small differences—a dust-caked valve or a left-open pressure relief—after listening to the stories of line operators who got splashed because of carelessness elsewhere in the chain.

    Environmental and Regulatory Demands: Our Responsibility Does Not End at the Factory Gate

    HCl gas deserves serious consideration regarding emissions and environmental impact. In our region, continuous monitoring and scrubber-equipped vent stacks reign in fugitive emissions. Local inspectors hold us to aggressive targets, and we accepted early on that open roof vents and “controlled losses” won’t cut it. Continuous investment in abatement technologies, from caustic scrubbers to real-time gas sensors, keeps our footprint in line with law and conscience. A while ago, regulatory authorities tightened limits on trace byproducts, sending many competitors scrambling to upgrade. We anticipated the change and extended periodic third-party audits across all our process lines. This move secured supply contracts for years while others faced fines and forced closures. Regulatory compliance matters not just for staying in business, but for protecting everyone living near our sites—and for guaranteeing regulatory compatibility for our industrial clients, who face audits from every direction.

    Transportation to international customers also requires respect for changing hazardous materials protocols. Documentation, labeling, and cylinder construction must meet not only domestic but international standards, often requiring harmonization updates on short notice. Our compliance team manages these evolving rules, making sure every load passes customs and international safety reviews. The challenges will only get sharper as Green Chemistry initiatives encourage stricter control over all chlorinated compounds. We have begun investing in research to capture and convert excess process HCl for use in less polluting syntheses, closing the loop as much as feasible.

    Improvements and Innovation: Listening to Those Who Use the Product

    Feedback from large users and hands-on operators drives most improvements in our product line. Pharmaceutical clients want purity above all, reporting back the slightest trace of metal ion as a potential process killer. We revised several stages of our purification and gas drying after a client’s mass spec picked up repeating peaks from a legacy pipeline that had visually passed all inspection. The fix was simple physically: new piping and more aggressive bakeout, but catching it required the close technical relationship built over repeat shipments and transparent quality tracking.

    Over in the electronics sector, speed of delivery began to rival purity in importance. We rolled out “production on demand” scheduling, syncing our storage and purification cycles with customers’ biggest runs. This move slashed turnaround time and trimmed down gas-lot aging, preserving the intended freshness and pressure tolerances of each cylinder. Direct communication between our plant and their tool engineers keeps small issues from snowballing, whether it’s a routine question about residual gas levels or the need for a special high-integrity valve.

    We rarely see the same set of priorities in glass and pigment industries. There, reliability and low impurity levels matter most in final clarity or batch color harmony. Most pigment manufacturers, for example, run continuous feed reactors with little tolerance for interruptions. If a shipment slips out of spec or is late, their process stalls and costs climb. Our approach—inventory linked to real-time customer forecasts, and technical assistance for plug-and-play connection—keeps them competitive. We found that by listening to our users’ daily frustrations, we not only solved their issues but created a stronger, more robust operation for ourselves.

    Future Challenges and the Importance of Genuine Manufacturing Expertise

    Anyone can move chemicals around or relabel a drum. True value comes from understanding molecules from the reactor through to application, caring about what works and what can fail. The growth in semiconductor miniaturization and the pharmaceutical push for absolute traceability will raise the bar for HCl producers worldwide. Counterfeit or low-quality gas can look the part—until it derails a million-dollar process or exposes users to danger.

    Green chemistry and emissions control will shape future HCl production as well. We expect further tightening of end-to-end recycling standards and increased customer pressure for carbon footprint data. Our focus rests on integrating continuous process monitoring, finding routes to capture all fugitive emissions, and investing in R&D for cleaner synthesis and recycling models. The challenge: maintain world-class product quality while addressing these new realities. This isn’t just compliance—it’s responsible stewardship of a potent industrial chemical.

    Closing Thoughts from the Floor

    Walk our production line, and you see inspection teams hot-walking cylinders, operators testing with the same urgency at shift’s end as at the start, and a technical manager on the rail to chase down the root of an anomaly. We’ve stuck around in HCl anhydrous manufacture because we believe true quality rests on connection with users, not just passing audits or moving inventory. It means training new team members on the why, not just the what, and keeping the stubborn determination to solve the field’s real problems.

    Hydrogen chloride anhydrous earned its place as both a critical raw material and a technical challenge. Only by recognizing what makes it valuable — dryness, purity, reliability, traceability — and fighting for those qualities down to the smallest details, do we serve both our toughest clients and our own standards for pride in manufacturing. That’s the factory difference.