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Hydrobromic Acid

    • Product Name Hydrobromic Acid
    • Alias Hydrogen bromide
    • Einecs 233-113-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    568175

    Chemical Name Hydrobromic Acid
    Chemical Formula HBr
    Molar Mass 80.91 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Pungent
    Density 1.49 g/cm³ (48% solution at 20°C)
    Boiling Point 122°C (48% solution)
    Melting Point -11°C (48% solution)
    Ph <1 (concentrated solution)
    Solubility In Water Miscible

    As an accredited Hydrobromic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Hydrobromic Acid is packaged in a 2.5-liter amber glass bottle with a secure, chemical-resistant cap and prominent hazard labeling.
    Shipping Hydrobromic acid is shipped in tightly sealed, corrosion-resistant containers such as glass, polyethylene, or Teflon bottles. It should be properly labeled and packed upright, kept away from incompatible substances. During transport, it requires secondary containment and must comply with hazardous materials regulations due to its corrosive and toxic nature.
    Storage Hydrobromic acid should be stored in a tightly closed, corrosion-resistant container, typically made of glass or specific plastics like Teflon, in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible materials such as bases and oxidizers. Ensure secondary containment to prevent spills and label the container clearly. Always use appropriate personal protective equipment when handling.
    Application of Hydrobromic Acid

    Applications of Hydrobromic Acid in Industrial Manufacturing

    As a dedicated manufacturer of Hydrobromic Acid (HBr), we supply global B2B partners with specialized grades for diverse downstream sectors. Here, we detail specific industrial application fields, technical requirements, processing stages, and finished products associated with Hydrobromic Acid to support formulation, compliance, and end-use performance.

    1. Pharmaceutical Active Ingredient Synthesis

    Pharmaceutical companies widely apply Hydrobromic Acid when producing brominated intermediates for APIs, especially in sedative, anticonvulsant, and anesthetic classes. HBr acts as a selective brominating agent or mineral acid during the halogenation and quaternization of complex organic compounds such as alkaloids and aromatic rings. Strict validation is performed to ensure low residual halides and high-purity intermediates meeting pharmacopoeia monographs before final conversion to dosage forms.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • USP, EP, and JP Monographs for raw material purity
    • FDA 21 CFR 210/211 for drug substance processing
    • REACH Registration for substance use in Europe

    Typical usage ratio

    • 0.5–2.0 molar equivalents relative to substrate depending on selectivity required
    • Amount adjusted to substrate structure and reaction yield targets

    Downstream process integration

    • Hydrobromic Acid addition in controlled reactors after substrate charging and inertization
    • Bromination or acidolysis step prior to intermediate crystallization and filtration
    • Acid scavenging and neutralization post-reaction under validated conditions

    Final product types

    • Bromhexine hydrochloride API
    • Ondansetron intermediates
    • Quaternary ammonium halide pharmaceuticals
    • Sedative and antiepileptic drug ingredients

    2. Inorganic Bromide Production

    Producers of alkali and alkaline earth metal bromides employ Hydrobromic Acid to achieve precise stoichiometry and low-contaminant conversion, particularly for potassium, sodium, and calcium bromide manufacture. The reaction ensures minimal residual sulfate or chloride compared to alternative routes. Its use is essential for quality requirements in photographic, oilfield, and drilling applications due to the high solubility and purity of resultant salts.

    Industry compliance standards

    • ASTM E234 for bromide analysis
    • ISO 9001:2015 certified quality assurance systems
    • API Recommended Practice 13K (for Oilfield Chemicals)
    • Food Chemicals Codex (FCC) for food-grade bromides

    Typical usage ratio

    • 1:1 molar ratio with respective hydroxide or carbonate
    • Adjusted for conversion yield and purity requirements

    Downstream process integration

    • Direct reaction in glass-lined or corrosion-resistant reactors
    • Neutralization followed by evaporation and crystallization
    • Post-production purification and drying for high-purity grades

    Final product types

    • Potassium bromide (pharmaceutical, photographic grade)
    • Sodium bromide (oilfield brine, drilling fluids)
    • Calcium bromide (completion fluids)
    • Ammonium bromide (analytical reagents)

    3. Flame Retardant Synthesis for Polymers

    Chemical processors use Hydrobromic Acid as a key reactant in the manufacture of organic brominated flame retardants, notably TBBPA (Tetrabromobisphenol A), DBDPE, and other brominated diphenyl ethers. Controlled bromination reactions require precise addition rates and temperature control to achieve target substitution levels while minimizing side reactions. High assay and low-iron Hydrobromic Acid is favored to prevent catalyst poisoning or color body formation in the final product.

    Industry compliance standards

    • UL 94 Flammability Standard requirements for additive efficacy
    • ISO 14001:2015 (environmental)
    • EU REACH Annex XIV for restricted substances
    • RoHS Directive 2011/65/EU (for electronics)

    Typical usage ratio

    • 1.2–1.8 molar equivalents relative to the phenol or ether base structure
    • Ratio set by required bromination degree per final product specification

    Downstream process integration

    • Reaction initiated after phenol or ether substrate preparation
    • HBr dosing controlled via in-line monitors for temperature and concentration
    • Post-reaction gas scrubbing and residue recovery systems utilized

    Final product types

    • Tetrabromobisphenol A (TBBPA) for printed circuit boards
    • Decabromodiphenyl ether (DBDPE) for thermoplastics
    • Brominated epoxy resins
    • Brominated polystyrene additives

    4. Catalyst and Alkylation Agent Preparation

    Industrial chemical plants integrate Hydrobromic Acid in the manufacture of alkyl bromide compounds, particularly when producing key alkylating agents like methyl bromide, ethyl bromide, and n-butyl bromide. These intermediates play a critical role as reagents or catalysts in pharmaceutical, agrochemical, and specialty synthesis. Water content and acidity must be carefully managed to prevent side reactions or downstream contamination of finished catalysts or halogenated intermediates.

    Industry compliance standards

    • ISO 9001:2015 for process quality assurance
    • Hazardous Substances Regulations for transport and storage
    • Environmental Protection Agency (EPA) guidelines for air and water emissions
    • Responsible Care® initiative for chemical handling

    Typical usage ratio

    • Excess molar equivalents (1.0–2.5) relative to alcohol or hydrocarbon substrate
    • Amount tuned by desired conversion rate and process throughput

    Downstream process integration

    • HBr introduced after alcohol substrate loading in batch or continuous reactors
    • Temperature and agitation monitored to facilitate efficient halogen exchange
    • Fractional distillation separates alkyl bromide from aqueous phase residues

    Final product types

    • Methyl bromide (fumigant intermediates, catalyst manufacture)
    • Ethyl bromide (synthesis building blocks, pharmaceutical raw materials)
    • N-butyl bromide (agrochemical intermediates, alkylation catalysts)
    • Specialty alkyl bromides for fine chemicals

    5. Organic Synthesis — Agrochemical Intermediates

    Agrochemical producers extensively utilize Hydrobromic Acid in the bromination of aromatic and aliphatic substrates for the targeted synthesis of herbicide, insecticide, and fungicide intermediates. Reaction control is essential to constrain byproducts and optimize halogen placement, supporting high-yield downstream processes. Many global clients specify advanced HBr grades to maintain critical purity for multi-step crop protection molecule synthesis.

    Industry compliance standards

    • FAO/WHO Technical Specifications for Pesticide Ingredients
    • ISO 17025-certified laboratory quality testing
    • Globally Harmonized System (GHS) for classification and labeling
    • Compliance with national environmental and workplace safety regulations

    Typical usage ratio

    • Typically 0.8–1.5 equivalents, adjusted for substrate reactivity and crop protection yield objectives
    • Ratio varies with process scale and specificity of brominated intermediate

    Downstream process integration

    • Feedstock bromination conducted in closed-loop reactors after substrate activation
    • Reaction quenching, phase separation, and purification ensure intermediate quality
    • Onward integration into condensation or amination reactions for finished actives

    Final product types

    • Brominated aromatic intermediates for herbicides
    • Brominated aliphatic precursors for fungicides
    • Pesticide building blocks
    • Specialty crop protection molecules

    6. Hydrobromic Acid as a Reducing Agent in Chemical Processing

    Specialty chemical manufacturers rely on Hydrobromic Acid as a controlled reducing agent for the conversion of organic nitro compounds to amines and for certain deprotection or dealkylation steps. Its strong acidity and specific redox profile enable efficient reaction kinetics with minimal byproduct formation compared to alternative acids. Accurate metering and in-process monitoring are mandated to ensure reaction endpoint control and product quality for downstream specialty chemical and monomer supply chains.

    Industry compliance standards

    • ISO 14001:2015 for environmental management during redox processing
    • REACH compliance for safe use documentation
    • Occupational Safety and Health Administration (OSHA) guidelines
    • GHS labeling for on-site storage and handling

    Typical usage ratio

    • 1.0–2.0 equivalents, carefully titrated based on substrate electron density and desired product purity
    • Ratio determined by lab-scale reaction parameters before scale-up

    Downstream process integration

    • Reductive processing after intermediate isolation
    • Continuous or batchwise addition via corrosion-resistant dosing systems
    • End-of-reaction neutralization and wastewater treatment

    Final product types

    • Aromatic amines for dyes and pigments
    • Pharmaceutical dealkylation/hydrolysis products
    • Fluorescent monomers
    • Specialty resins and polymers
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    Certification & Compliance
    More Introduction

    Hydrobromic Acid from the Manufacturer’s View: What It Takes to Produce Real Quality

    Understanding Hydrobromic Acid: Beyond a Simple Commodity

    In our own factories, the production floors don't sleep. Among the many products coming off the lines, Hydrobromic Acid always demands hands-on attention and technical expertise. Sitting in the drum or tank, it's a clear, colorless liquid with a sharply pungent smell. Chemically, you've got HBr in aqueous solution, though what matters most in the daily work is focus on purity, concentration, and integrity. Every stage gets strict controls. The acid makes its place not just for a specific use, but for the expectations customers have grown to trust over years.

    The Models We Manufacture: Concentration Makes a Difference

    We routinely manufacture Hydrobromic Acid at concentrations of 48% and 62%. The choice of concentration reflects years of customer feedback and practical application demands. The 48% model remains the industry standard, easy to handle and delivering reliable performance for general applications. The 62% variant gets its orders for more demanding synthesis and specialty applications where higher reactivity yields a cleaner, more efficient reaction. We stick close to these two ranges because they work best for the main industries — but every batch is made to match the technical parameters essential in precise processes.

    How We Keep It Pure: Real-World Measures

    In this business, purity makes or breaks the product. Bromide salts, chlorine, sulfur compounds — these contaminants always try to sneak in during production. Our approach isn’t just about keeping an eye on the gauges. Every staff member, from batch maker to QA technician, works from a list of checkpoints. We draw samples mid-batch. Routine titrations and chromatographic analyses get done constantly, not just at batch end. In the early days, some would claim ninety-eight percent purity sufficed. These days, physical properties like color and pH get tested along with trace-metal analysis down to ppm levels. We keep iron and heavy metals tightly controlled, because even a few ppm will cause headaches for downstream fabrication.

    We don’t count on “average” results and never lean on batch blending to hit numbers. Customers using Hydrobromic Acid for high-purity organics, APIs, or electronic intermediates notice residues quickly. They call back if a process goes off. Our commitment gets tested every time these high-demand industries order from us again. Holding fast to our processes isn’t about ticking off a regulatory checklist, but about relationships built one shipment at a time.

    How Hydrobromic Acid Gets Used in the Real World

    Lab talk and textbook lists won't tell the whole story. In day-to-day operations, our Hydrobromic Acid heads straight to:

    These applications have real financial impact. Waste a tank or a batch, the loss is measured not in gallons but in days, dollars, and reputation. End users rely on us to solve processing problems ahead of time because starting with stable, high-purity acid heads off troubleshooting after it’s already in the line.

    Why Hydrobromic Acid Isn’t the Same as Other Acids

    People try to swap acids when they're in a pinch — not every chemist or operations manager knows immediately that Hydrobromic Acid plays a unique role nothing else steps into cleanly. The strong acid strength (pKa ≈ -9), higher than hydrochloric acid and many others, lets it drive substitution and addition reactions more efficiently. More importantly, it introduces bromide ions specifically, which is impossible with alternatives like HCl or HI without unwanted contaminants or secondary side reactions.

    Reliance on hydrochloric acid, for example, might result in incomplete reactions or lower yields where the process chemistry actually calls for the unique properties of bromide. Iodide-based processes often result in lower stability and higher cost, and HI is harder to handle and regulate for consistent commercial production.

    For processes that demand exact bromide content — such as making brominated intermediates, or whenever trace metals or halide ion ratios need watching — Hydrobromic Acid remains the responsible option. Trying to adapt another acid leads to lost time, material wastage, and often extra treatment or purification steps. This isn’t just a lab nuance: at scale, it’s about process reliability and total cost.

    Safe Storage and Real-World Distribution

    Years of experience have shown us that the real risks with Hydrobromic Acid don’t always show up in textbooks. The acid interacts with everything from warehouse concrete to metallic pumps. Improper packaging or transfer methods cause leaks or concentration loss, eating away safety and profit. We’ve moved away from generic HDPE drums whenever purity must remain above 99% for extended periods. Glass-lined steel tanks have proven their worth for both transport and plant storage, maintaining long-term stability.

    Distribution always means adapting to local climate, handling infrastructure, and regulatory frameworks. In some places, we work with local tank farms for bulk users. In others, prefilled carboys get shipped out in temperature-controlled containers. Regulatory paperwork slows things down, but a missed customs report or mislabeling can do far worse — create danger, product loss, or regulatory liabilities. Working with authorities isn’t optional, it’s as much part of chemical manufacturing as running production itself.

    Our logistics staff solve problems that don’t fit any script. A sudden humidity spike, port delay, or rainfall means checking seals and even batch retesting. We never send out shipments “just good enough” — we’ve seen too many disasters trace back to cutting corners on storage or paperwork.

    Environmental Issues and Our Approach to Waste Management

    Hydrobromic Acid has an environmental footprint driven by both production and disposal. Small leaks, vapor loss, or improper disposal can trigger large responses from inspectors and local communities. Over the years, the best controls have come from containment, monitored neutralization, and responsible employee training. Older designs dumped dilute acid; we now have neutralization tanks and in-line sensors logging pH and bromide levels every minute.

    We recover and recycle as much as possible. Aqueous waste streams get processed before discharge. Sludge and residue get treated via licensed hazardous waste contractors. What’s changed in recent years is tighter regulation, requiring not just logs, but automated systems that leave little room for operator error. Far from viewing this as a nuisance, clean handling cuts down on lost product, keeps local authorities cooperative, and boosts community trust. Reputations in chemical manufacturing live or die by the community’s willingness to accept you as a neighbor.

    Health and Occupational Safety: The View from the Production Floor

    Production workers face Hydrobromic Acid in its most unforgiving form. Without decent personal protective equipment, exposure burns, eye damage, and long-term health risks are real. Off-gassing in a poorly vented tank room can drop air quality quickly, even in modern facilities.

    Our crews work in acid-rated gloves, full face shields, and with continuous ventilation. We run regular training not just for “compliance,” but because nobody forgets their first careless burn. Experienced workers guide the new hands, often with their own stories painted in acid etchings on boots or floor tiles. We’ve seen far too many injuries in lackadaisical operations elsewhere — and the fallout is always human.

    There’s no substitute for culture that values safety. The rules don’t protect workers — discipline and group pride do. We’ve invested heavily in air quality monitors, local exhaust, and proper water wash-down facilities. These aren’t nice add-ons; they’re essential for operation. The best plants we know run on respect between coworkers, not a wall of outdated warning posters.

    Process Innovation: Making a Better Product

    Hydrobromic Acid manufacturing isn’t about pouring and waiting. Improved reaction design means water and bromine contact more efficiently, yielding higher-purity acid with fewer byproducts. We constantly review raw material selection: sourcing high-grade bromine makes life easier down the line, reducing filtration and post-treatment costs.

    Automation has changed how we handle batch processes. Real-time process analytics alert us to contamination before it travels downstream. Having digital records for every batch brings quicker traceability during an audit or customer inquiry. Modern vacuum distillation units prevent acid decomposition and minimize operator exposure.

    Investing in these systems costs more at first, but downtime in an acid plant quickly outweighs short-term savings. Running reliable equipment means we keep serving regular customers year after year instead of solving the same old quality complaints.

    Acid strength measurement, titration with silver nitrate, and mass balance calculations have all moved toward digital integration. This saves technician time and gives management tight control over yield and rework rates. We’ve reduced process upsets by more than half over the last decade, saving money that would otherwise have vanished into lost batches.

    Serving Different Markets: Customization and Bulk Needs

    Hydrobromic Acid doesn’t move by itself. Bulk orders for industrial users — such as brominated flame retardant manufacturers or metal cleaning operations — require flexibility in packing and delivery. From the factory, tanks sometimes head out on rail, sometimes by truck. Each delivery means choosing liners, valves, and seals to prevent cross-contamination with other materials.

    Smaller labs, or those working under good manufacturing practice (GMP), ask for certified lots with full traceability, detailed impurity profiles, and special documents for authorities. We meet these not just with a printout, but by keeping records open for audit. This level of transparency costs staff time, yet it allows for faster approvals and smooth transitions when supply chain changes crop up.

    Some customers demand special blends — lower concentrations for safer storage, or even acid prepared with deionized water for sensitive electronics work. Each new request means our plant managers sit down with production and QA to make sure every tweak keeps the product stable and clean.

    Challenges and Solutions in Hydrobromic Acid Production

    No production run ever follows the textbook entirely. Weather, power outages, raw material quality fluctuations, and equipment breakdowns all happen. It’s the manufacturer's job to solve these without letting product quality slip. Old-school plant managers know to smell, watch, and sample constantly, not just wait for instrumentation to sound alarms.

    Raw material pricing for bromine goes up and down with supply and geopolitical risks. We hedge this by working close with reliable suppliers, and never dropping quality just to hit a price. Customers have learned the difference between stable, consistent product and spot buys from resellers who skip corners in quality assurance.

    One recurring issue is wastewater management. Our installation of secondary neutralization and recycling systems has reduced both cost and community complaints. Investing in double-containment and advanced leak detection paid for itself the first time a line rupture was caught before it reached the drains.

    Training and operator knowledge transfer beat out technology alone. We lose experienced people to retirement and competition. For that reason, we’ve structured mentorship into the daily operations. This isn’t a classroom exercise; it’s the difference between a missed valve setting that ruins a tank and a quick catch that saves the lot. Real-world know-how, not just theoretical understanding, determines production reliability.

    The Difference the Manufacturer Makes: A Matter of Accountability

    Resellers and distributors hand off problems as soon as the truck leaves their dock. As the manufacturer, our name travels with every shipment. The feedback comes directly to us — not filtered through several middlemen. A phone call from a plant superintendent, a late-night email from a chemist in trouble with a process upset: these all land on our desks, and we answer them because we made the product.

    Our technical team supports troubleshooting in the customer’s process, not just with generic data sheets but with real troubleshooting advice. This involvement builds trust and long-term partnerships. The win: customers bring problems to us early, and together, batches, schedules, and safety get managed with far less waste.

    We never forget that every drum represents more than an order — it’s a line of trust built through consistent delivery, technical know-how, and honest handling of mistakes. That’s what sets real manufacturers apart in the Hydrobromic Acid market.

    A Focus on Longevity and Responsible Growth

    Chemical markets never stand still. More users now ask for sustainable sourcing, better emissions control, and transparent reporting practices. We’ve invested in emission scrubbing, process heat recovery, and renewable energy for auxiliary needs. New environmental targets drive us to stretch each improvement while keeping the core of our production reliable.

    We think of growth not just in volumes sold, but in the years we can continue to operate as a trusted local and global player. That means keeping the next generation of chemists and operators trained, safe, and proud to work in an industry that too often gets misunderstood outside its walls.

    In a product like Hydrobromic Acid, real quality always returns to the factory floor — where batch by batch, the lessons of the old hands and the demands of new technologies come together to serve industries that count on us for consistency, technical reliability, and straight answers.