|
HS Code |
598060 |
| chemical_name | Fumaroyl Chloride [Trans] |
| molecular_formula | C4H2Cl2O2 |
| molecular_weight | 169.97 g/mol |
| CAS_number | 3562-84-3 |
| appearance | Colorless to pale yellow liquid |
| boiling_point | 102-104°C at 20 mmHg |
| melting_point | 6-9°C |
| density | 1.421 g/mL at 25°C |
| solubility | Reacts with water |
| refractive_index | n20/D 1.529 |
As an accredited Fumaroyl Chloride [Trans] factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Fumaroyl Chloride [Trans], 100 grams, packaged in a sealed amber glass bottle with a tamper-evident cap and hazard labeling. |
| Shipping | Fumaroyl Chloride [Trans] is shipped in tightly sealed containers under dry, cool conditions, typically as a corrosive chemical (UN 3265). It should be kept away from moisture and incompatible substances, with appropriate hazard labeling. Shipping follows all regulatory guidelines for hazardous materials to ensure safety during transportation. |
| Storage | Fumaroyl Chloride [Trans] should be stored in a cool, dry, and well-ventilated area, away from moisture, heat, and incompatible substances such as strong bases and oxidizers. Keep the container tightly closed and protected from direct sunlight. Use corrosion-resistant containers, and store under an inert atmosphere if possible, as it hydrolyzes readily upon exposure to moisture, releasing toxic gases. |
Applications of Fumaroyl Chloride [Trans] in Industrial ManufacturingFumaroyl Chloride [Trans] serves as a critical intermediate in several specialized chemical industries. As a direct producer, we supply this material to manufacturing sectors with stringent requirements for reactivity, purity, and compliance. Our application overview explores actual downstream scenarios where our material provides distinct technical advantages in process efficiency, product integrity, and regulatory conformity. 1. Synthesis of Specialty Polyamide ResinsIn advanced polymer manufacturing, major formulators use this compound for producing aromatic and semi-aromatic polyamides, targeting applications such as high-temperature resistant fibers and engineered plastics. The compound introduces fumaric-based rigid structures into polymers, enhancing chemical resistance and thermal properties. Operators at resin plants dose it during controlled step-growth polymerization, typically reacting with diamines under dry, inert conditions. This pathway ensures compliance with safety standards, minimizes byproduct formation, and achieves molecular weight requirements suitable for automotive, electrical, and mechanical component production. Industry compliance standards
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2. Pharmaceutical Active Ingredient IntermediatesThe pharmaceutical industry utilizes this acyl chloride as a building block for synthesizing drug intermediates, specifically those incorporating fumaric or maleic acid derivatives for improved bioavailability. Custom synthesis groups employ the material in amide coupling reactions and esterifications under GMP conditions. Strict batch monitoring ensures residue limits and traceability. The reagent’s purity and minimal side product profile meet regulatory filings for APIs produced at multi-tonne scale, particularly for targeted oncology and antiviral drug classes. Industry compliance standards
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3. Production of Crosslinking Agents for CoatingsThe material is valued in coatings manufacturing for the synthesis of advanced crosslinkers, particularly those seeking rigid, UV-resistant networks. Producers of industrial coatings react it with polyols or diamines to develop multifunctional crosslinking agents, enhancing abrasion resistance and chemical stability of topcoats. Our manufacturing partners manage reaction exotherms, dosing, and moisture control to guarantee safe production and reproducible performance. Finished crosslinkers meet regulatory demands for automotive, aerospace, and industrial protective coatings requiring extended service lifetimes. Industry compliance standards
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4. Agrochemical Synthesis IntermediatesAgrochemical formulators use the compound at scale to prepare herbicide and fungicide intermediates based on bis-acyl derivatives. The reactivity facilitates selective functionalization, enabling high yields of actives with tailored isomeric ratios. Processing teams operate under closed-system handling, aligning with environmental and workplace safety mandates. Our technical service supports downstream adaptation to continuous or batchwise agrochemical manufacturing, optimizing throughput and impurity control. Industry compliance standards
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5. Production of Ester Plasticizers and ModifiersManufacturers of specialty ester plasticizers use this compound in esterification with linear or branched alcohols, creating additives with enhanced migration resistance and low volatility for PVC and engineering polymers. Reaction parameters require efficient HCl removal, precise temperature staging, and continuous in-line purity monitoring. The process produces esters suited for wire and cable insulation, automotive interiors, and construction film, with compliance to regional and global material safety protocols. Industry compliance standards
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Manufacturing chemicals requires a tight grasp of both material qualities and real-world performance in demanding conditions. Fumaroyl Chloride [Trans] stands out in our lineup not just for its reactive power as a diacid chloride but for its consistency in every batch we produce. As a manufacturer who oversees every kilogram from raw fumaric acid to the final bottles shipped, I see the compound up close – clear, sometimes faintly yellow, with a distinct pungency. Its chemical structure unlocks a level of reactivity commercial chemists seek for specialty polycondensation and organic synthesis.
Specs alone don’t tell its story. We produce Fumaroyl Chloride [Trans] in several purities, but most of our industrial partners request 98 percent and above, with moisture content kept well below half a percent. Particle size falls below detection because we deliver it in liquid form, packed air-tight to avoid hydrolysis. Most requests come for volumes ranging from drums of 25 kilograms up to intermediate bulk containers, and on rare occasion, a custom fill for development work in the field. Every batch must meet our solar-grade standard for clarity, ensuring trace byproducts sit lower than 0.5 percent, because trace impurities can derail flavor chemistry, advanced polymers, or pharmaceutical builds.
Daily production of Fumaroyl Chloride [Trans] feels like threading a needle in a hurricane. During conversion from fumaric acid, temperature swings or air moisture can spoil product inside the reactor before you know it. We fine-tune reactors with continuous monitoring, using real-time FTIR and moisture probes. One slip with the phosgene feed or poorly cleaned vessel, and you’re backflushing or tossing a batch that fails color specs or hydrolyzes. Other chemical makers sometimes struggle with batch-to-batch color drift or hidden impurities that show up only when downstream customers push the envelope—think new electronics materials, UV-resistant polyesters, high-end UV-cure coatings.
We’ve learned one basic truth: starting with pristine fumaric acid and running phosgenation dry, at tightly controlled temperatures, gives the best result. We avoid over-chlorination by controlling stoichiometry with feedback curves, not hope. Packing lines get flushed with nitrogen and dried in ovens before startup. Years ago, we saw customers’ analytic data pointed out trace maleoyl chloride in older lots—byproduct from isomerization—so we tuned our reactors, adjusted agitation, refined distillation, and cut maleic isomer down to an undetectable blip. Operations like this look simple on paper, but any gap in drying, vessel design, or crew training can set yield back more than a week, so we sweat the smallest details, running pilot lots before scaling up new procedures.
With dual acid chloride groups locked in the trans-configuration, this compound opens doors that other C4 diacyl chlorides can’t. High-end polyesters benefit most. We’ve watched formulators add minute quantities of our product to change the glass transition temperature, create UV-cured industrial adhesives, and produce flexible yet tough polymers for automotive trim. Pharmaceutical customers count on it for peptide coupling, linker synthesis, and as a building block for experimental antivirals. Flavor and fragrance chemists run it as a fleeting intermediate—never as a finished additive, but essential when forging pathways to more complex alkenyl and alkynyl acids. Some agricultural research still taps it for custom active ingredient scaffolds.
Our customers in coatings see tangible gains: Fumaroyl Chloride [Trans] gives thin films with higher photo-reactivity and energy absorption, extending lifetime of UV-cure products. Polyester producers integrate minute amounts for backbone modification, producing clear sheets with fine-tuned flexibility and less tendency to organize into brittle crystallites. Chemical engineers have told us they gain better control over crosslink densities and can run colder curing processes by using our product over isophthaloyl or phthaloyl chloride.
Not all diacid chlorides work the same. Customers sometimes ask if they can swap in maleoyl chloride or terephthaloyl chloride when Fumaroyl Chloride [Trans] supply tightens; the answer we see in production is “not if you want the same result.” Trans configuration stiffens the backbone in polyesters and blocks ring formation that can occur with cis-isomers. Maleoyl chloride, the cis isomer, brings down melting points and tends to react faster with nucleophiles, but synthesized polymers often fall short on clarity and toughness. Isophthaloyl and terephthaloyl chlorides, while stable and easier to handle, lack the same alkene character and bring more rigid aromaticity. Switching between these acids can make or break a new polymer or frustrate flavor engineers aiming for consistent yields and product performance.
In direct use, Fumaroyl Chloride [Trans] brings higher UV-resistance, less yellowing, and improved weathering compared to maleic-based polyesters. We’ve watched customer pilots prove that in solar panel encapsulation, Fumaroyl Chloride [Trans] derivatives outlive their maleic counterparts, which yellow faster under high-energy exposure. Compared to linear aliphatic diacid chlorides, ours imparts better solvent and heat resistance in final resins.
Every year, we process hundred-ton volumes, but a single off-spec batch can cost six figures in lost time, customer loyalty, and downstream impact. Analysts demand purity exceeding 98 percent for bulk orders and 99.5 percent for high-end electronics and pharmaceutical partners. Water content under 0.5 percent keeps reaction yields high. Heavy metal content must remain below detection, especially for pharma runs; we meet pharma-grade specs with ICP accreditation and traceability from feedstock through to container cleaning protocols. We run full GC, NMR, and HPLC on every batch and track COA trends alongside customer returns and field failures.
A recurring request from the field calls for longer shelf stability. No matter how dry we make it, exposure ruins entire orders if bottles or drums aren’t sealed airtight. We teach customer teams to double-check seals, purge transfer lines, and never use Teflon-lined gaskets—hydrogen chloride generated during storage degrades PTFE and spoils product. A few customers found that glass-lined reactors work far better than stainless, which can pit and shed trace iron into the product.
There’s no room for error handling Fumaroyl Chloride [Trans]. Phosgene residues or hydrolysis products can cause corrosive fumes, and we’ve learned to tune our fume hoods to capture every fraction. From drum filling to end-user transfer, staff wears full PPE, and neutralization systems stay ready before the first valve opens. Even a tiny leak, unnoticed at drum transfer, can trigger alarms or worse, so we stick to air-tight transfers, pressure-tested before shipment. Once, we lost an entire container because a shipper mishandled seals—customers lost both time and trust. Since then, every shipment has a tamper-evident seal, and our team writes a log of container conditions before and after departure.
Years back, one of our partners dealt with an accident due to improper venting. After investigating, both companies invested in custom vented closures that trap hydrochloric acid, protecting handlers and keeping product grade intact even during months at sea. We share those supply chain improvements with any new partner, believing that safe handling up front heads off downstream trouble.
Chemical manufacturing sits at the crossroads of commodity volatility and regulatory scrutiny. We source fumaric acid from regional plants running benzene-free routes, cutting off old hydrocarbon-sourced impurities before they ever see our reactors. Our feedstock arrives double-bagged, dry, and tested for trace metal content, so each reaction starts with minimum uncertainty.
Being a caretaker of both product and environment means tracking phosgene balance, capturing HCl offgas, and recycling solvents wherever possible. For every ton of Fumaroyl Chloride [Trans] produced, there’s a chain of environmental safeguards—gas scrubbing, solvent distillation, and careful off-site disposal contracts. Our new pilot-scale reactor runs continuous phosgenation with close-loop control. We also invest in CO2 capture at the front end and use heat recovery on the exothermic steps. These steps cost money, but pay back in waste reduction and improved batch quality.
Problems inevitably happen on the factory floor. The most common trouble involves hydrolysis or trace contaminant carryover. If storage drums see a temperature cycle or incautious transfer, even unopened packaging can draw in a whiff of moist air. We worked with packaging engineers to improve seals with multi-layer foil induction liners and anti-static layers. Sometimes a customer’s analytics team uncovers a faint yellow streak in what should be water-white liquid; we track these cases and compare to the plant’s daily records, checking vessel cleaning logs and recent maintenance windows. Usually, better cleaning and process discipline fix the root cause.
Scale-up brings its own headaches. Early pilot runs sometimes gave unintentional color, haze, or byproduct crescent peaks. Modern PLC-controlled reactors now run eligible feedback loops with dual pH and temperature checks every minute. We calibrate sensors every batch. Our in-house chemists collaborate with process engineers to tune reflux rates, stirrer speeds, and distillation cuts. There’s no substitute for having operators and supervisors comparing analytic data direct from the instrument bench, face-to-face with the same people who run the pumps and transfer lines.
No two customers handle Fumaroyl Chloride [Trans] the same way. Some high-end research labs demand sub-kilogram lots packed in glass ampules, triple-sealed and couriered overnight, while major plastics manufacturers pull pallet-scale drums into automated feeders. We’ve built dedicated filling rooms for customers working on battery films, since even fingerprint moisture on a transfer line can tweak conductivity and ruin a lot. Agricultural chemicals partners sometimes blend our product direct into one-pot syntheses, cutting reaction times by 30 percent compared to older staged acid chlorides.
Feedback pushes us to evolve. Pharmaceutical buyers run ever-more-stringent analytics, especially for genotoxicity. Every time one detects a new impurity, we close the loop, rerun pilot lots, and adjust procedures. Flavor producers tell us what impurity signatures show up in GC/MS, pushing us to incrementally improve cleaning and drying cycles. Some packaging engineers suggested improved vented closures two years ago, which cut customer complaints by half and stabilized trans-isomer ratios during bulk storage.
Behind every drum of Fumaroyl Chloride [Trans], there are operators in charge of everything from blending and packing to documenting every drum. I walk the plant floors every shift, and it’s clear who’s got a keen eye for moisture control or who can spot a line pressure drop before alarms ring out. Every employee who’s handled the product knows the sting of a missed step—a poorly dried line, a missed tightening of a valve, or a rush to clear a filter. We foster a culture where catching issues early matters as much as meeting batch quotas; blame-free reporting and quick responses catch problems at the source.
Training never stops. We run biannual refresher courses, not just on chemical handling, but on analytics and storage know-how too. Our teams regularly visit customers to trace problems, teach proper decanting, and swap stories on handling in difficult weather or remote conditions. More than once we’ve sent senior engineers to troubleshoot a customer’s process, bringing back insights for our own production lines. The trust built over years keeps lines running smoothly, minimizes downtime, and delivers a product that holds up even in the toughest chemistries.
Regulatory tides shape our work more every year. Specialty chemicals now face tighter restrictions on by-products, trace solvents, and waste effluent. Electronics and medical device firms hold us to global standards for traceability, residue control, and environmental impact. To meet those growing needs, we roll out new process technologies before regulations land. Reactors built for minimal solvent use, continuous offgas capture, and full batch traceability are no longer optional in our plant; they’re built into every new line.
Customers in solar, flavors, life science, and coatings keep pushing the envelope. Future development aims at purer grades and smarter packaging design. We are investing in analytics that go beyond HPLC and NMR, heading into mass spec and high-sensitivity elemental analysis. We track external research on low-phosgene alternatives, greener acid chlorides, and new polymer chemistries to keep our own R&D team fresh.
Industry-wide, demand for high-purity Fumaroyl Chloride [Trans] looks set to grow. Battery storage, green energy, flavor chemistry, and advanced medicine will keep chasing smaller impurities and higher consistency. We see ourselves as partners in delivering more than just a molecule—providing technical support, process knowledge, and continuous improvement that grows with each customer’s ambition.
In the rush for ever-cleaner, more reliable specialty chemicals, Fumaroyl Chloride [Trans] holds a place not for convenience but for performance nobody can replicate with lower-grade or poorly controlled substitutes. Factories run smoother, research projects finish on time, product lines hit targets, and safety stays front and center when you use the right grade, stored and handled the right way. As manufacturers, we answer to both technical excellence and the people who trust our work down the line—from operators and process engineers to the end-users who rely on quality in every bottle and drum shipped.