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Ethylenimine

    • Product Name Ethylenimine
    • Alias Aziridine
    • Einecs 202-468-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    749500

    Cas Number 151-56-4
    Molecular Formula C2H5N
    Molar Mass 43.07 g/mol
    Appearance Colorless liquid
    Density 0.832 g/cm3 (at 20°C)
    Melting Point -77°C
    Boiling Point 56-57°C
    Flash Point -21°C (closed cup)
    Solubility In Water Miscible
    Vapor Pressure 133 mmHg (at 20°C)

    As an accredited Ethylenimine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Ethylenimine, 500 mL, is packaged in a sealed amber glass bottle with a screw cap, labeled with hazard and safety information.
    Shipping Ethylenimine must be shipped in tightly sealed containers, protected from light, heat, and moisture, and clearly labeled as a toxic and flammable substance. Transportation follows strict hazardous materials regulations—typically in UN-approved, corrosion-resistant drums, with appropriate placarding, and documentation in compliance with international and local chemical shipping laws.
    Storage Ethylenimine should be stored in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible materials such as acids, oxidizers, and halogenated compounds. The storage container must be tightly sealed, made of appropriate materials like stainless steel, and kept under an inert atmosphere to prevent polymerization and decomposition. Proper labeling and secondary containment are essential for safety.
    Application of Ethylenimine

    Applications of Ethylenimine in Industrial Manufacturing

    Ethylenimine, known for its high reactivity and functional versatility, plays a fundamental role in multiple industrial sectors. Our direct manufacturing expertise ensures tight control over purity and consistency, meeting the stringent requirements of critical downstream applications. Below, we detail major industrial uses for ethylenimine with specific attention to regulatory standards, formulation rates, incorporation stages, and final goods.

    1. Synthesis of Polyethylenimine (PEI) for Water Treatment Chemicals

    Major global water treatment manufacturers incorporate ethylenimine to produce polyethylenimine, a polycationic polymer employed for heavy metal chelation, sludge dewatering, and microbial control. Compliance with environmental protection protocols remains essential throughout production, as regulatory agencies closely monitor chemical use in potable and industrial water treatment. We supply ethylenimine with trace impurity control for direct polymerization, supporting customers’ adherence to both international safety standards and application-specific technical requirements.

    Industry compliance standards

    • U.S. EPA Safe Drinking Water Act—CFR Title 40, Part 141
    • EU REACH Regulation No. 1907/2006 for chemical safety
    • China GB/T 5750 for potable water treatment agents
    • ISO 9001:2015 for supplier quality management in specialty chemicals

    Typical usage ratio

    • Polymerization batch formulas typically add ethylenimine at 5–15 wt% relative to expected final PEI mass, adjusted per target molecular weight and branching level.

    Downstream process integration

    • Ethylenimine is introduced in the polymerization reactor under inert atmosphere at temperatures of 40–60°C, using controlled initiators or catalysts for chain growth and branching control.

    Final product types

    • Polyethylenimine flocculants for municipal and industrial water clarification
    • Chelating agents for wastewater heavy metal removal
    • Sludge dewatering polymers

    2. Epoxy Resin Curing Agents for Electrical Insulation Materials

    Electrical insulation composite manufacturers use ethylenimine to synthesize modified amine curing agents, significantly enhancing resistance to heat aging and dielectric breakdown in demanding environments. Upstream quality and regulatory conformance remains critical due to downstream exposure in grids, transformers, and electrotechnical components deployed worldwide. We maintain strict batch documentation to ensure confidence in safety and compliance at every step.

    Industry compliance standards

    • IEC 60454 and 60216 for electrical insulating materials
    • UL 1446 for electrical insulation systems
    • RoHS Directive 2011/65/EU for hazardous substance restrictions
    • REACH SVHC control for amine derivatives

    Typical usage ratio

    • Final curing agent formulations typically contain ethylenimine derivatives at 2–10 wt% of total resin mass, depending on crosslinking density and service temperature performance.

    Downstream process integration

    • Chemical modification of ethylenimine takes place prior to blending with epoxy resins. The resulting amine hardeners are dosed into premix stations immediately before potting, casting, or lamination steps.

    Final product types

    • Cast resin insulators for switchgear and transformers
    • Laminated electrical insulation boards
    • High-voltage components for utilities infrastructure

    3. Paper Wet-Strength Resin Additives

    Paper mills integrate ethylenimine-based polymers to impart high wet-strength durability to specialty papers used in packaging, hygiene, and technical grades. The role of these cationic resins is vital in maintaining sheet integrity during end-use exposure to moisture. Regulatory authorities require careful assessment of residual monomers and migration, particularly for grades in contact with food or medical products.

    Industry compliance standards

    • BfR Recommendation XXXVI for paper and board in contact with food (Germany/EU)
    • U.S. FDA 21 CFR 176.170 for resinous and polymeric coatings in paper products
    • ISO 9001:2015 for process traceability in papermaking chemicals
    • EN 15593 for hygiene in packaging supply chain

    Typical usage ratio

    • Application levels range from 0.5–2% dry on dry fiber weight, depending on grade requirements, end-use moisture exposure, and conversion machinery.

    Downstream process integration

    • Wet-strength resin is prepared by in situ polymerization or by bringing in pre-polymerized solutions. Mills meter the resin solution directly into pulp slurry ahead of paper sheet forming sections.

    Final product types

    • Wet-strength packaging paper (corrugated, liquid containers)
    • Hygiene grades (napkins, hand towels)
    • Label and technical papers for industrial use

    4. Pharmaceutical Intermediate for Semi-Synthetic Antibiotics

    Ethylenimine serves as a critical intermediate for the N-alkylation of core β-lactam antibiotics, specifically in the synthesis pathways of drugs such as ampicillin and cephalexin. Pharmaceutical manufacturers require documentation on residual solvent, byproduct profiles, and compliance with international pharmacopoeias. Our production supports validated supply under pharmaceutical GMP, consistently satisfying cGMP and DMF requirements for regulated markets.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia Monograph 01/2013:0254 for ampicillin
    • U.S. FDA 21 CFR Parts 210/211 for finished pharmaceuticals
    • DMF (Drug Master File) compliance for global regulatory registration

    Typical usage ratio

    • Scale-up processes employ stoichiometric plus minimal excess (5–10% over molar requirement) to maximize alkylation yield and minimize downstream purification loads.

    Downstream process integration

    • Ethylenimine is charged to reactor vessels under closed conditions, reacting with acid or amide precursors through multi-step organic synthesis. Subsequent separation and purification yield the target semi-synthetic antibiotic.

    Final product types

    • Bulk pharmaceutical intermediates for β-lactam antibiotics
    • Final oral and parenteral antibiotic preparations after formulation
    • Veterinary β-lactam actives

    5. Rubber Chemical Modifier for Tire Performance Enhancement

    Major tire producers introduce ethylenimine-based compounds as specialty rubber modifiers to manage crosslink density, improve rolling resistance, and optimize dynamic performance in demanding automotive applications. Compliance aligns with tire industry safety and environmental protection benchmarks, while formulations require precise ratio adjustment based on compound design and tread composition.

    Industry compliance standards

    • ISO 9001:2015 for automotive and tire chemical quality control
    • UN ECE Regulation No. 117 for wet grip and rolling resistance
    • EU REACH Regulation No. 1907/2006 for tire chemical registration
    • U.S. TSCA (Toxic Substances Control Act) Section 8 compliance

    Typical usage ratio

    • Rubber compounds accept ethylenimine derivatives at 0.1–1.5 phr (parts per hundred rubber), with optimizations driven by specific end-use performance targets and compounding process efficiency.

    Downstream process integration

    • The modifier is added during bulk compounding, ahead of vulcanization. Integration occurs in Banbury mixers or inline continuous mixing systems, ensuring dispersion before curing.

    Final product types

    • Tread and sidewall compounds for PCR, TBR, and OTR tires
    • Technical rubber parts subject to high mechanical stress (beltings, seals)
    • Automotive vibration-damping components

    6. Textile Finishing for Antistatic and Soil-Release Treatments

    Producers of functional textiles employ ethylenimine-derived polymers in textile finishing formulations to impart durable antistatic characteristics and soil release capability on synthetic fibers. Regulatory pressure drives close scrutiny of chemical additives contacting skin or being subjected to consumer washing cycles. We maintain tight analytical controls supporting OEKO-TEX and other safety benchmarks relevant to global textile supply chains.

    Industry compliance standards

    • OEKO-TEX Standard 100 for textile chemical safety
    • EU REACH Annex XVII compliance for restricted substances
    • ISO 14001 for environmental management in textile finishing
    • ZDHC Manufacturing Restricted Substances List (MRSL)

    Typical usage ratio

    • Pad-finishing baths use ethylenimine polymer solutions at 1–5 g/L, adjusted for textile weight, fiber type, and targeted wash durability.

    Downstream process integration

    • After dyeing and rinsing, ethylenimine-derived polymers are applied in finishing baths during padding, followed by drying and curing at specified temperatures to anchor the treatment onto fiber surfaces.

    Final product types

    • Apparel with inherent antistatic and soil-release properties (workwear, uniforms)
    • Home textiles such as upholstery and carpeting
    • Technical fabrics for automotive and industrial filtration
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    Certification & Compliance
    More Introduction

    Ethylenimine: A Closer Look from Our Factory Floor

    Experience in Responsible Manufacturing

    Plant workers and chemists come across raw power and risk every day when they stand beside an Ethylenimine reactor. This isn’t a chemical you treat lightly—it demands respect, and every batch we produce becomes a real-world lesson in precision and safety. Having handled Ethylenimine for decades, our teams realize not only its capability as a building block but also the unique challenges it brings from the moment we charge the reactor to the time we tank the final product.

    Physical Traits and Onsite Testing

    Ethylenimine, or aziridine, stands out as a colorless liquid, volatile, and pungent. In the lab, it boils around 56°C. Storage requires careful mitigation of potential polymerization, so our lines and storage tanks get regular inspections. Flammable and toxic, yes—but that’s just one part of the story. Every technician values the substance’s high reactivity and recognizes the edge it offers for synthesis, from crosslinking agents to epoxy modifiers.

    As a chemical producer, quality isn’t an abstract promise. We track water content and purity through every batch, running each drum through gas chromatography before it leaves the facility. We know the pressure of batch-to-batch consistency, as a small deviation in impurity levels can disrupt our customers’ downstream synthesis. For us, it’s not just a specification on a sheet; it’s nights spent tweaking columns and fine-tuning the distillation cut-points.

    Why Ethylenimine Matters

    This tiny aziridine ring packs potential way beyond its modest appearance. Each year, we ship to fiber manufacturers, pharmaceutical labs, and specialty resin companies. A good share of the epoxy crosslinkers the world relies on start right here, where we carry out controlled, small-lot production that cares about employee health as much as downstream product quality.

    Ethylenimine acts as a monomer, bringing unique three-membered ring strain and reactivity. Our customers need that molecular strain—they want rapid ring opening, strong chemical linkages, and results that milder amines can’t touch. Since aziridine derivatives react aggressively with carboxylic acids, alcohols, or anhydrides, careful catalyst selection during our process helps us deliver a cleaner, more controlled chain-termination step. That means downstream users work with fewer side reactions and less venting during their own process.

    Comparing with Other Building Blocks

    As a manufacturer, we often get asked why not use ethylene oxide, propyleneimine, or one of the classic amines instead. The honest answer lies in the molecule itself. Ethylenimine offers stronger ring strain, which unlocks high reactivity toward nucleophiles. For epoxide formulators, switching to a simple amine gives up that efficiency in chain extension or curing. Ethylenimine-cured resins reach different hardness and flexibility. Textile crosslinking shows a jump in wet strength, with aziridine units offering bridging power that outperforms many alternatives.

    On the plant floor, we constantly compare processes, handling safety data, and batch purity between Ethylenimine and those other amines. Ethylene oxide may share volatility hazards, but it doesn’t build the same aminated polymers or crosslinkers—the ring chemistry leads production in two separate lanes. We’re candid about the tradeoffs: Ethylenimine storage requires tight protocols, and our teams train each incoming operator about both its hazard profile and its unique synthesis performance.

    Sustainable Handling and Worker Safety

    After decades managing Ethylenimine, we have learned that even a small release isn’t just an environmental risk but also an immediate health hazard. The skin and respiratory dangers stand front and center. That means more than following paperwork; it means maintaining triple-redundant containment, frequent air quality and leak detection, and ensuring every operator wears positive-pressure respirators. We’ve built our training modules around real-life incidents, making sure no batch is charged or drained unless controls check out.

    For the remote-control operators and floor sample runners, there’s never room for shortcuts with Ethylenimine. Frequent exposure tracking through health monitoring gives us data: for nearly ten years, strict handling has kept incident rates low enough that local regulators use our plant for best-practices seminars. We take pride in this, but our focus never shifts—we upgrade sensors, test extraction at every valve, and rotate handling personnel to avoid overexposure. Zero-incident records don’t happen by accident.

    Specs We Stand Behind

    After years refining our columns, we consistently reach above 99.5% purity through standard batches. Trace water gets knocked down to under 200 ppm, and we verify those numbers not just to meet a spec, but as a sign of pride. Other manufacturers sometimes gloss over the importance of minor impurities—We’ve seen poorly-controlled aziridine batches gum up entire downstream reactors, and one leaky drum can set off costly downtime. Our lab doors stay open to customer audits. Transparency isn’t just a buzzword we post online—any customer can walk our floor and compare logs, batch by batch.

    Barrels leave our gates sealed and traced back to real shift numbers and reactor logs. If a batch runs late, that’s fine—our shipping crew waits until QC signs off. If a shipment turns, we don’t tell logistics to “move faster;” we scrap the batch and retrain the crew. That’s one advantage of manufacturer-controlled output: no market pressure to push substandard resin or crosslinker onto a customer. Our competitors sometimes let logistics override quality, but our approach builds longer relationships with formulators who’d rather pay for reliability.

    Upstream Adjustments Translate to Downstream Value

    A pound of Ethylenimine sets off more chemical possibilities than most monomers we ship. Waterborne coatings labs demand strict impurity profiles—one batch with too much sodium or chloride, and the whole day’s run can turn out full of gels or off-color product. Working this closely with final users shows us which impurities matter most; we adjust our upstream conditions to keep those contaminants out.

    Specialty fiber companies also keep us on our toes. These firms call us with fine-detail questions about chain branching, off-gassing during their polymerizations, or the subtle traces of byproduct amines. We listen and change reactor protocols in response. That’s a benefit of not being tied to the batch-in, batch-out approach of larger commodity firms: nimble enough to modify feed, endpoints, and even storage chemistry to lock out issues before the shipment even loads.

    Challenges Unique to Chemical Manufacturing

    Making Ethylenimine safely at scale demands more than textbook chemistry. Market volatility, raw material quality swings, and environmental expectations all shape how we run our units. For example, higher cost acrylonitrile or variable hydrogen feedlines in winter force us to shift batch sizes or revise distillation schedules. Equipment maintenance on our jacketed reactors means we face more downtime in colder months—but we plan buffer stock and extra heating, not just to keep batch times steady, but to prevent runaway reactions or out-of-spec feeds.

    Those sorts of plant-level realities don’t show up in simple spec sheets. Our shift leads talk directly with engineering to decide which batches can flex composition parameters to meet a customer’s application—never a call to a distant sales office. If a pharmaceutical grade client needs a purer cut, engineering walks QC to the reactor and adjusts recycles and column cuts. If a resin-maker wants a tailored solvent blend, we consult with downstream partners, not just send out a data sheet. Each run through our plant becomes a real-time negotiation between science and production engineering.

    Environmental Practices and Community Relations

    Our plant neighbors a rural community, and we believe in showing our environmental controls, not just claiming them. Any batch release triggers a direct report to the community council. Odor controls, mobile gas monitors, and regular fence line air tests back up what we claim in our environmental filings. We let school science classes tour our labs because we know public trust springs from visible action, not just company statements about “sustainability” and “responsibility.”

    Process improvements matter to us because we don’t want to contribute to the historical stigma of chemical manufacturing. We’ve adopted tighter vapor recovery, moved away from older, leak-prone equipment, and now reclaim almost all of the byproduct amines and water. Having neighbors understand why our process looks the way it does matters as much to us as any inspector’s record. Local groundwater testing and yearly open-house forums let residents ask tough questions. That feedback filters right to the top and gets real responses in investment and plant policy.

    Why Experienced Handling Still Matters

    Producing Ethylenimine well isn’t just about meeting a purity number or regulatory filing. The learning curve stretches over years: new plant operators shadow veterans, and chemists spend months watching offgas monitors and polymerization lines before taking the helm. Responsibility sits heavy on those charged with reactor patrols. Even our leadership rotated through night shifts before they sat at boardroom tables.

    That kind of institutional experience breeds a culture that values transparency. We don’t try to hide batch hiccups or QC failures behind paperwork. Each challenge adds to our collective knowledge. Our safety meetings run with actual incident data—if a pump failed and caused a near-leak, everyone reviews what failed, not just the crew on duty. If a regulatory inspector highlights a gap, we call an all-staff huddle, revise protocols, and follow up with real-world drills, not just update the SOP manual.

    Our Roots and Forward Focus

    Old hands at the plant still remember when Ethylenimine shipped in steel drums with hand-written tags and basic inspection. The industry has come far, and we pride ourselves on adopting every proven improvement that history and research offer. These days, every shipment leaves with digital tracking, double locks, and tamper-proof seals. Real-time temperature and pressure monitoring spot any batch deviation before drums hit the shipping dock.

    On the research front, our team works closely with polymer scientists and application chemists to study how even minor formulation tweaks in Ethylenimine can open up new high-value uses. Water-resistant coatings, pharmaceutical intermediates, specialty surfactants—all see direct benefits from steady improvements in manufacturing quality. Our lab develops cleaner, more efficient catalysts, tracks impurity profiles, and adapts real-world data from downstream plants.

    These efforts make Ethylenimine production safer, cleaner, and more reliable than ever before. We don’t claim perfection, but our track record speaks to the dedication, knowledge, and real-world care our teams bring to every run. Every batch carries the mark of a hands-on process, shaped by human decisions, facing unpredictable realities, and always striving to give customers what they expect from a true hands-on manufacturer.