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Ethylene glycol monomethyl ether

    • Product Name Ethylene glycol monomethyl ether
    • Alias EGME
    • Einecs 203-483-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    372323

    Chemicalname Ethylene glycol monomethyl ether
    Casnumber 109-86-4
    Molecularformula C3H8O2
    Molecularweight 76.09 g/mol
    Appearance Colorless liquid
    Odor Sweet, ether-like
    Boilingpoint 124 °C
    Meltingpoint -85 °C
    Density 0.964 g/cm³ at 20°C
    Solubilityinwater Miscible
    Vaporpressure 6.3 mmHg at 20°C
    Flashpoint 43 °C (closed cup)
    Refractiveindex 1.400 at 20°C

    As an accredited Ethylene glycol monomethyl ether factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Ethylene glycol monomethyl ether is packaged in a 200-liter blue HDPE drum with a secure screw cap and clear hazard labeling.
    Shipping Ethylene glycol monomethyl ether should be shipped in tightly sealed, properly labeled containers, protected from physical damage. It must be transported in compliance with regulations for hazardous materials (UN 1188), typically as a flammable liquid (Class 3). Store away from incompatible substances, heat, and ignition sources during shipping.
    Storage Ethylene glycol monomethyl ether should be stored in a tightly closed, clearly labeled container, in a cool, dry, well-ventilated area away from heat, sparks, and open flames. Keep it away from incompatible materials such as strong oxidizers and acids. Storage areas should have spill containment, and containers must be protected from physical damage and checked regularly for leaks.
    Application of Ethylene glycol monomethyl ether

    Applications of Ethylene Glycol Monomethyl Ether in Industrial Manufacturing

    Ethylene glycol monomethyl ether (EGME) plays a vital role across multiple high-value industrial sectors. As a direct manufacturer, we supply EGME based on strict adherence to international compliance, with direct support for formulation and process integration. Below, we detail critical industrial segments utilizing EGME, providing data on compliance, usage levels, process steps, and end markets.

    1. Electronics Industry: Semiconductor and Photolithography Solvents

    Semiconductor plants use EGME extensively as a photoresist solvent, cleaner, and developer assistant in wafer fabrication lines. EGME’s high solvation power and controlled volatility enable precise stripping and cleaning for photolithography stages. Fabricators adjust its use based on target critical dimensions and defectivity requirements. Stringent environmental and occupational health controls dictate solvent selection and blend ratios to minimize residue and contamination. EGME forms part of engineered solvent blends for deposition processes and post-exposure residue removal, directly impacting device performance and line yield in advanced nodes.

    Industry compliance standards

    • SEMI S2 – Environmental, Health, and Safety Guideline for Semiconductor Manufacturing Equipment
    • OSHA 29 CFR 1910.1450 – Occupational Exposure to Hazardous Chemicals in Laboratories
    • IEC 62474 – Material Declaration for Products of and for the Electronics Industry
    • Cleanroom ISO 14644 standards for contamination control

    Typical usage ratio

    • 10–25 wt% as a photoresist stripper component
    • 15–35 wt% in custom cleaning blend, adjusted for process node and residue type
    • Lower-range usage for fine-line work; higher ratios for thick-film processes

    Downstream process integration

    • Stage: Applied in wet-bench and track equipment after photolithography
    • Direct addition to pre-formulated chemical baths or automated chemical delivery systems
    • Process: Used in wafer cleaning, stripping, and resist residue removal steps
    • Purity and water content monitored continuously during recirculation

    Final product types

    • CMOS wafers for logic chips
    • DRAM and NAND memory structures
    • Photolithographic masks
    • MEMS sensors for automotive and consumer electronics

    2. Paints and Coatings: Waterborne and High-Performance Systems

    Industrial paint and coatings formulators rely on EGME for its coalescing and solvent properties, particularly in waterborne paints for automotive, construction, and industrial equipment. It supports pigment dispersion, improves leveling, and helps regulate evaporation rates critical for film formation. Usage levels depend on system viscosity and desired drying time, often balanced against VOC regulations and indoor air quality mandates.

    Industry compliance standards

    • EU REACH Regulation (EC) No 1907/2006 – Restrictions on EGME for consumer paints
    • US EPA 40 CFR Part 59 – National Volatile Organic Compound Emission Standards for Consumer Products
    • GB 18582-2020 – Indoor Architectural Coatings National Standards (China)
    • ISO 11890-2 – Paints and Varnishes Determination of VOC Content

    Typical usage ratio

    • 2–8% by weight in waterborne paint formulations
    • Up to 20% in specialty industrial coatings, subject to local VOC caps
    • Level varies based on binder compatibility and finish requirements

    Downstream process integration

    • Added during pigment dispersion and millbase processing
    • Incorporated into letdown stage post-neutralization
    • Blended in with other coalescents and rheology modifiers
    • Monitored by in-process GC and viscosity tests

    Final product types

    • Automotive OEM and refinish paints
    • Industrial machine coatings
    • Architectural wall paints
    • Container and packaging coatings

    3. Specialty Inks: Flexographic and Gravure Printing Applications

    Manufacturers of packaging and publication inks choose EGME for its solvency and slow evaporation to maintain ink performance at press speeds up to 600 m/min. Used in flexographic and gravure systems, EGME enables deep color development and uniform ink transfer across a range of substrates including plastics and metallized films. Ratios must align with migration limits in food-contact applications and offset risk of ink set-off.

    Industry compliance standards

    • US FDA 21 CFR Parts 175–178 – Indirect Food Additives: Paper and Paperboard Components
    • Swiss Ordinance on Materials and Articles in Contact with Food (SR 817.023.21)
    • CEPE Guidance – Printing Inks for Food Contact Materials
    • EN 646 – Determination of Color Fastness of Paper and Board

    Typical usage ratio

    • 10–30% by weight in flexo & gravure ink bases
    • Lower end for labels and folding cartons; higher for flexible films
    • Level adjusted to substrate absorbency and printing speed

    Downstream process integration

    • Mixed during pigment wetting and resin dissolution stage
    • Final ratio set during pre-press ink balancing
    • Strict batch control and log for each print run
    • GC analysis for residual solvent on print samples

    Final product types

    • Flexible packaging films for snack and dairy
    • Printed paperboard food cartons
    • Beverage bottle labels
    • High-volume advertising inserts

    4. Chemical Synthesis: Intermediate for Pharma and Agrochemical Manufacturing

    Pharmaceutical and agrochemical producers utilize EGME as a polar reaction solvent in the synthesis of key active ingredients where its miscibility with organic and aqueous phases facilitates controlled reaction rates. EGME’s utility in heterocyclic synthesis, esterification, and nucleophilic substitution governs process output, influenced by reactor system design and purification protocols. Tightly managed impurity profiles must meet pharmacopeial or crop protection regulations at multiple production stages.

    Industry compliance standards

    • ICH Q7 – Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF – United States Pharmacopeia specifications for residual solvents
    • EU Regulation 1107/2009 – Plant Protection Product Authorization
    • ISO 9001:2015 – Quality management processes for chemical manufacturing

    Typical usage ratio

    • Solvent volumes: 1.2–3.5 L per mol reactant for pharma synthesis
    • Agrochemical processes: 5–15% solvent-to-reactant ratio by mass
    • Adjusted to achieve optimal reactant solubility and selectivity

    Downstream process integration

    • Added into jacketed reactors during charge-up phase
    • Removed post-reaction by solvent swap or distillation under reduced pressure
    • Residual analysis via GC/FID or LC-MS to validate removal
    • Recovery and recycling steps tracked for regulatory reporting

    Final product types

    • Active Pharmaceutical Ingredients (APIs)
    • Selective herbicides and fungicides
    • Pharmaceutical intermediates for further downstream use
    • Crop protection premixes and concentrates

    5. Battery Electrolyte Formulations: Lithium-Ion Cell Manufacturing

    EGME supports lithium-ion battery manufacturers as a co-solvent to improve electrolyte viscosity and enhance lithium salt solubility, particularly in high-energy cell types. Manufacturers use finely tuned ratios to maintain cycle stability and safety at wide temperature ranges. Process integration includes moisture-controlled blending rooms, with in-line Karl Fischer titration to monitor water content, ensuring consistent cell performance and shelf life.

    Industry compliance standards

    • IEC 62660-2 – Secondary Lithium-Ion Cells for Automotive Applications – Safety and abuse testing
    • UN/DOT 38.3 – Transport of Dangerous Goods for Li-ion cells and batteries
    • UL 2580 – Batteries for Use in Electric Vehicles
    • ISO 9001/ISO 14001 – Quality and Environmental Management in Battery Plants

    Typical usage ratio

    • 1–8% by volume in non-aqueous electrolyte compositions
    • Ratio varies based on cell chemistry (NMC, LFP, NCA) and operating temperature requirements
    • Lower use for high-rate discharge cells; higher for energy-dense, high-voltage types

    Downstream process integration

    • Introduced in anhydrous mixing units with lithium salt and base solvents
    • Continuous agitation to maintain homogeneity before electrolyte injection
    • Quality confirmation by Karl Fischer and GC-MS before cell filling
    • Strict exclusion from contact with cell assembly air

    Final product types

    • Lithium-ion battery cells for electric vehicles
    • Stationary grid storage batteries
    • Consumer electronics power cells
    • High-temperature industrial powerpacks
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    Certification & Compliance
    More Introduction

    Ethylene Glycol Monomethyl Ether: Bringing Formal Chemistry to Everyday Industry

    Our Experience in Producing Ethylene Glycol Monomethyl Ether

    Standing behind every drum of ethylene glycol monomethyl ether (EGME), we are reminded every day that chemistry shapes industrial growth in direct ways. We have produced EGME for decades, closely monitoring every fraction that leaves our reactors. Each batch reflects both the discipline of science and the practical realities of the trade. We began producing this solvent when few local manufacturers did, scaling capacity in sync with changes across coatings, electronics, pharmaceuticals, and inks.

    We have found that the reliability of EGME owes as much to the raw materials as it does to the equipment. For every ton we manufacture, safety and quality are tracked at each step, from raw ethylene oxide input to the finished solvent stored under temperature-controlled conditions. Our plant chemists monitor moisture levels very closely and maintain high purity, usually greater than 99.5%, which meets industry demands for solvent performance.

    This consistency comes from a hands-on process. Over the years, we learned that even minor fluctuations in temperature or pressure shift the distribution of byproducts. We devote more labor to washing, distillation, and purification than the textbooks suggest, since unreacted residues or subtle impurities in EGME can throw off downstream formulations.

    Specifications That Matter in Daily Use

    Every specification on our EGME leaves a mark on how it functions in your shop, plant, or laboratory. The clear, colorless nature of EGME is not a trivial point: customers in paints and ink industries use this quality to avoid unwanted shades or tints in final blends. Its low viscosity, about 1.7 centipoises at room temperature, allows for efficient mixing.

    The water miscibility of our product stands out—water will blend with EGME in all proportions, letting formulators in coatings or cleaning products build solutions that behave predictably under various environmental conditions. Boiling point (about 125°C) and flash point (close to 43°C) guide both storage and use, since these characteristics often direct which solvent is chosen for a line or job.

    Because purity shapes everything from evaporation rate to compatibility with other ingredients, our process aims for minimal aldehyde and acid content. Each batch is checked for water content, which we keep below 0.1%. In spectrophotometric and chromatographic tests, this translates into less byproduct or yellowing. There is no shortcut—experience teaches us to monitor all these parameters to avoid headaches for those who depend on our product.

    Our Role Supplying for Coatings, Electronics, and Pharmaceuticals

    Formulators in the coatings industry appreciate the solvency power of EGME. During annual shutdowns and audits, we speak directly with plant managers and chemists who need a solvent that dissipates quickly, leaves minimal residue, and blends with both water-based and solvent-based systems. Artists’ inks and specialty paints both benefit from the clean evaporation of EGME, which lets colors “pop” and dry to an even finish.

    The electronics industry presents its own set of challenges. EGME finds its way into precision cleaning solutions for electronic components, where residues are intolerable and microscopic contaminants interfere with performance. From circuit board assembly to delicate lens cleaning, every part per million makes a difference. We have been called on to custom-produce ultra-low water content EGME for semiconductor sites—one major client needed levels below 500 ppm—and meeting these needs taught us to refine both our analytical methods and our distillation technology.

    Pharmaceutical manufacturing relies on EGME’s ability to dissolve both polar and nonpolar substances. We hear from pharmacists and plant technicians who need solvents for active ingredient extractions, intermediates, or cleaning applications. The product must function without leaving behind impurities that could threaten batch safety or integrity. In recent years, pharmaceutical standards have only tightened. We upgraded filtration and handling abroad and regularly invest in GMP-aligned practices at home.

    Key Differences Between EGME and Other Glycol Ethers

    As a manufacturer, we can explain first-hand that all glycol ethers do not solve the same problems. A common question we field is how EGME stacks up against other options such as ethylene glycol monoethyl ether (EGEE) or ethylene glycol monobutyl ether (EGBE). The answer rests in the molecular structure and how that structure determines evaporation, solvency, toxicity, and miscibility.

    With its methyl group, EGME is lighter than EGEE, and this influences everything from drying time to vapor pressure. In fast-drying inks or coatings where quick surface set is needed, EGME gives better results. EGEE and EGBE, with their larger ethyl and butyl groups, bring slower evaporation and change the solvency balance. EGBE’s broader use for cleaning, especially in degreasers, reflects this. We always suggest our customers compare evaporation and compatibility profiles in their lab, since small differences in glycol ether structure can yield significant practical changes.

    Another often-overlooked point is regulatory acceptance and health considerations. EGME, while prized for its solvency, has stricter controls in workplaces compared to some heavier glycol ethers. We work with our customers to review local exposure limits, labeling requirements, and personal protective equipment recommendations. Our technical support teams explain detailed handling procedures and assist with compliance documentation to ensure that regulatory and safety standards are not just met but anticipated.

    Quality Control: Keeping Promises with Every Drum

    Manufacturers who take shortcuts usually find their product rejected at best and causing failures at worst. We have dedicated labs running titrations, chromatography, water determination, and contamination screens. For high-purity, conductive ink, or electronics applications, we deliver analysis sheets detailing each batch’s profile on request.

    Even after so many years, we train new employees on the "why" behind sampling and inspection. The learning curve never ends. For example, we once uncovered a trace impurity caused by a gasket leak during a routine GC/MS screen. The team isolated the batch and spent days cleaning equipment, rejecting suspect product, and upgrading the inspection schedule. Quality is not a marketing phrase for us—it is measured in actual time, labor, and money invested.

    We invite independent audits to keep us honest. Customers fly in from other countries to review our plant floors, labs, and dangerous goods handling. Many return for long-term contracts, since they know we do not hide behind exterior branding or sales offices. For every contract negotiated, we follow up with real people—not call scripts or third-party agents—if problems or questions arise.

    The Impact of Responsible Manufacturing on Environment and Safety

    Chemistry has influence beyond the immediate plant walls. From the beginning, we have taken the stance that we are caretakers in how EGME affects both people and the environment. The substance brings with it known health and safety issues, as all professionals in our field are aware. We train all staff to respect the potential—EGME can be absorbed through the skin, and long-term exposure limits have dropped globally. That shapes every part of our storage, handling, and shipping.

    We invested early in closed-system transfer pumps, vapor recovery, and backup containment. As regulations rose, our company's environmental officers drove process upgrades. Our systems are equipped to catch spills at every step, using sumps, double-sealed tanks, and dedicated fire-suppression for flammable liquids. We selected every valve and joint with both efficiency and safety in mind. Routine drills test our staff and our local community response team on emergency shutdown, first aid, and decontamination procedures.

    Waste minimization has real costs, but it has become a core focus. Much of our investment went into solvent reclaim and recycling units that strip and recover EGME from still bottoms and cleaning operations. This reduces the amount of solvent waste incinerated or sent to specialized disposal, and improving the recovery fraction means both better economics and reduced environmental risk. We collaborate with local regulators to report emissions, adopt new waste treatment technologies, and demonstrate transparent data on all outbound shipments.

    How Changing Chemical Markets Shift Demand

    The world market for glycol ethers is not static. Industries reinvent their formulas with every annual product release, regulation, or consumer trend. Demand for EGME now links directly to the fortunes of the electronics field, certain fast-drying coatings, and pharmaceutical production. Recent years have seen tighter workplace exposure standards in many countries, raising the bar for workplace controls.

    Our response as a manufacturer has meant both backward and forward integration. We have forged long-standing partnerships with upstream suppliers of ethylene oxide, and downstream relationships with major users, from national-scale paint firms to boutique ink producers. This helps us anticipate not just month-to-month shifts, but how underlying trends will shape demand in the next five or ten years.

    Price spikes in feedstock ripple through to finished cost. Geopolitical tensions or changes in port accessibility alter our shipping schedules. Some years, surges in electronics and electric vehicle growth generate tight supply, while regulatory shifts spark new questions for importers. Our team manages both logistics and supply allocations directly. We don’t rely on intermediaries for critical decisions—we ship, deliver, and problem-solve ourselves, adjusting tank inventories to buffer both expected and surprise disruptions.

    Supporting Customers Across the Spectrum

    We support a customer spectrum that ranges from megatons in multinational plants to single caged IBCs for a new research project. Many of our customers are repeat buyers who have relied on us for years, but we also welcome small-batch experimentation or new market entrants. No matter the scale, we bring technical advice, supply consistency, and practical troubleshooting to the table.

    We have sat across tables from procurement managers worried about spec drift, plant supervisors tracking a paint line shutdown to contaminated solvent, and researchers developing a new battery chemistry that depends on absolute purity. Our team works directly with yours to catch problems before they escalate. Recent consultations have included on-site training for safe handling, real-time support during plant commissioning, and joint lab efforts to qualify EGME in new synthesis pathways. The best outcomes come from openness—sharing full test reports, service records, and safety documents, not just product delivery.

    Over the years, our staff have built up not just professional knowledge, but also an understanding of the “unwritten rules” of practical manufacturing—what labs really need on an urgent delivery, how to clear customs on a short deadline, or what alternative supply looks like during a production bottleneck. These are not skills taught in chemistry textbooks. Staying connected to both the technical world and the world of real customers keeps us at the front of the business.

    The Move Toward Safer, More Sustainable Alternatives

    Markets continue to push for safer and greener solvent choices. EGME remains useful for many applications because nothing else, so far, matches its blend of solvency and volatility in some formulations. Yet, as manufacturers, we follow signals from both customers and safety agencies that the future will demand alternatives.

    We stay informed through regulatory bulletins and the innovation coming from research institutes in Europe, America, and Asia. Some customers now request glycol ethers with longer alkyl chains—where lower toxicity replaces the speed of evaporation as the critical criteria. Our technical experts help customers trial replacements in waterborne paints or electronics cleaning. In some cases, using a heavier glycol ether or a blend reduces workplace risks, but every switch involves tradeoffs. Performance, cost, shelf-life, and process compatibility all enter the calculations.

    We do not take “greener” to simply mean “different.” As new solvents, bio-based chemicals, or novel blends reach pilot stage, their entire health and environmental profiles need real testing and validation. Some of our long-term clients ask us to run head-to-head trials between EGME and new candidate chemicals, sharing neutral lab results and real-world process feedback. In transitioning markets, our role often shifts from being only a supplier to helping shape the next line-up of industry solvents.

    Building for Tomorrow: Our Commitment to the Chemistry Community

    As a chemical manufacturer, our daily work connects us to more than molecules and metrics. The reliability of EGME changes how a customer completes a contract, scales a product, or meets both technical and safety standards. Every day spent monitoring, testing, and adjusting makes our EGME a little more dependable for those who rely on it.

    We continue to learn and improve. With each technology breakthrough or regulatory update, the whole chemical community adapts. We invest in training, equipment, and transparent communication because old solutions rarely satisfy new challenges. Our long-term relationships with formulators, plant engineers, and regulators allow us to see change coming and respond thoughtfully.

    Practical chemistry stays grounded in real work and informed by real users. We welcome partnerships that stress test our approach, push for better safety, or challenge us to meet rising standards. Making EGME remains both a science and a craft—one shaped by feedback, oversight, and a respect for those who, like us, want every drum to deliver exactly what it promises.