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Ethyl Sulfuric Acid

    • Product Name Ethyl Sulfuric Acid
    • Alias Ethanesulfonic acid
    • Einecs 214-681-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    822001

    Chemical Name Ethyl Sulfuric Acid
    Iupac Name Ethyl hydrogen sulfate
    Molecular Formula C2H6SO4
    Molar Mass 126.13 g/mol
    Cas Number 127-68-4
    Appearance Colorless liquid or solid
    Solubility In Water Highly soluble
    Density 1.29 g/cm³
    Pka 1.73
    Odor Odorless
    Melting Point 14°C (57°F)

    As an accredited Ethyl Sulfuric Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Ethyl Sulfuric Acid is packaged in a 500 mL amber glass bottle with a secure, chemical-resistant cap and hazard labeling.
    Shipping Ethyl Sulfuric Acid should be shipped in tightly sealed, corrosion-resistant containers, protected from moisture and incompatible substances. Transport must comply with local, national, and international regulations for hazardous materials. Use secondary containment to prevent leaks, and clearly label all packages. Ensure proper documentation and emergency procedures are included during transit.
    Storage **Ethyl Sulfuric Acid** should be stored in a cool, dry, and well-ventilated area, away from direct sunlight and incompatible materials such as bases, oxidizers, and water. Use corrosion-resistant, tightly closed containers clearly labeled with hazard warnings. Regularly inspect storage areas for leaks or signs of deterioration, and ensure access to emergency spill containment and appropriate personal protective equipment (PPE).
    Application of Ethyl Sulfuric Acid

    Applications of Ethyl Sulfuric Acid in Industrial Manufacturing

    Ethyl Sulfuric Acid plays a critical role in various industrial sectors by participating directly in synthesis, catalytic processes, and intermediate reactions that are essential for producing high-quality finished products. Our commitment as a manufacturer is ensuring consistent purity, controlled reactivity, and reliability from batch to batch to meet the strict demands in each downstream segment where this intermediate is essential.

    1. Textile Dye Intermediate Synthesis

    In the textile and dye manufacturing sector, Ethyl Sulfuric Acid acts as a key sulfonating agent for the preparation of dye intermediates, such as ethylated sulfonic acid derivatives and specific azo dye components. These intermediates require finely controlled sulfonation to achieve proper dye purity, colorfastness, and compatibility with textile fibers. The raw material enters precisely during the sulfonation step after pre-treatment and before final coupling reactions, impacting the yield and shade properties of batch-produced dye lots. The application must align with textile and ecological compliance due to the presence of sulfur-containing substances throughout the process flow.

    Industry compliance standards

    • REACH Regulation (EC No 1907/2006) for chemical safety
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals – Manufacturing Restricted Substances List)
    • OEKO-TEX® Standard 100 for finished textile dyes
    • European Directive 2002/61/EC (azo dyes directive)

    Typical usage ratio

    • 5–15% wt relative to total reactant mass; the exact amount depends on the specific dye structure and required sulfonation level

    Downstream process integration

    • Introduced post-alkylation during the controlled sulfonation of aromatic amines or phenols to produce intermediate compounds; followed by neutralization and purification steps

    Final product types

    • Reactive dyes (cellulosic textiles)
    • Direct dyes
    • Acid dyes
    • Textile pigment intermediates

    2. Pharmaceutical Active Intermediate Preparation

    Ethyl Sulfuric Acid is utilized in pharmaceutical chemistry for the synthesis of active pharmaceutical ingredient (API) precursors, especially in the formation of organosulfur intermediates and protection or activation steps for alcohol groups. Its well-regulated introduction ensures precise modification of molecular functionality without undesired side reactions. Manufacturers apply it strictly under cGMP protocols, integrating it at stages requiring stable ethylation or sulfonation while upholding stringent traceability and impurity control necessary for drug synthesis.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for APIs
    • USP (United States Pharmacopeia) and Ph. Eur. (European Pharmacopoeia) specifications for reactant purity and residue limits
    • 21 CFR Part 211 (FDA cGMP for finished pharmaceuticals)
    • EMEA/CHMP/QWP/396951/2006 for starting materials in APIs

    Typical usage ratio

    • 0.5–2.5 molar equivalents based on substrate; quantity varies according to target substrate and desired conversion efficiency

    Downstream process integration

    • Applied during selective sulfonation of heterocyclic building blocks, functional group protection, or etherification steps after pre-purification and prior to API isolation

    Final product types

    • API intermediates for anti-infectives and antihypertensives
    • Regioselectively modified pharmaceutical excipients
    • Sulfonated drug precursor compounds

    3. Agrochemical Intermediate Manufacturing

    The agrochemical industry incorporates Ethyl Sulfuric Acid into multi-step syntheses for select herbicide and fungicide intermediate molecules. By introducing sulfate ester moieties at specific molecular positions, this raw material facilitates key activation and solubilization functions in downstream pesticide formulation. Batch records must document controlled feed rates and conversion yields, as the presence of unreacted acid can affect both crop safety and regulatory approval, especially in high-throughput production sites.

    Industry compliance standards

    • FAO/WHO JMPR (Joint Meeting on Pesticide Residues) guidelines
    • EPA 40 CFR Part 180 (tolerances for pesticide chemicals in food, USA)
    • ISO 25198:2021 (Industrial chemicals – Sampling and analysis of pesticide technical materials and formulation)
    • China GB 2763 (Maximum residue limits for pesticides in food)

    Typical usage ratio

    • 3–8% by weight, based on total reaction mix; adjustments made according to substrate reactivity and regulatory residue thresholds

    Downstream process integration

    • Dosed at the esterification or sulfonation phase for primary chemical transformation or solubilizing group introduction; followed by neutralization and downstream purification

    Final product types

    • Herbicide and fungicide intermediates (e.g., sulfonylurea herbicide building blocks)
    • Water-soluble agrochemical additives

    4. Electroplating Bath Additive Manufacturing

    Within the metal finishing sector, Ethyl Sulfuric Acid supports manufacturing of additives used to control brightness and leveling in electroplating baths, particularly for copper and nickel applications. Its main advantage lies in serving as a sulfate source while imparting controlled conductivity and grain refinement properties during deposition. Operators must manage precise dosing to balance solution pH, ionic strength, and minimize deposit brittleness, guided by in-process titration and analytical monitoring.

    Industry compliance standards

    • ASTM B567/B568 (electroplating coating thickness standards)
    • ISO 12686 (Electroplated coatings – qualification procedures)
    • RoHS Directive (2011/65/EU) for restricted substances in finished articles
    • REACH SVHC compliance for bath constituents

    Typical usage ratio

    • 0.2–1.5 g/L in plating baths; values determined by target deposit characteristics and substrate size

    Downstream process integration

    • Added as a concentrated solution during bath preparation or as a maintenance component to restore sulfate content and control additive profile during production cycles

    Final product types

    • Electroplated copper components (circuitry, connectors)
    • Electroplated nickel surfaces (decorative hardware, corrosion-resistant parts)
    • Metallic coatings for consumer electronics

    5. Pharmaceutical Tablet Coating Agent Synthesis

    Ethyl Sulfuric Acid operates as a reactant during the chemical modification of cellulose used in enteric and sustained-release tablet coatings. The reactivity enables introduction of sulfonate ester groups that confer stability and tailored solubility profiles in coating polymers, critical for API release characteristics and patient compliance. Manufacturers charge it into high-shear reactors where precise reaction temperature and pH are continually monitored to control the degree of substitution and minimize crosscontamination with process byproducts.

    Industry compliance standards

    • USP/NF for excipient quality requirements
    • Ph. Eur. General Monographs (Coating agents for tablets)
    • 21 CFR Part 172 – Food additives permitted for direct addition to food for human consumption (for excipient status)
    • FDA Inactive Ingredients Database (for use in solid oral dosage forms)

    Typical usage ratio

    • 0.8–2.0% by weight, calculated on dry cellulose mass; modified per target film thickness and dissolution profile requirements

    Downstream process integration

    • Charged during chemical derivatization and sulfonation of cellulose or starch-based polymers, followed by thorough washing, neutralization, and purification before final tablet coating formulation

    Final product types

    • Enteric-coated tablets
    • Sustained-release oral dosage forms
    • Modified-release pharmaceutical film coatings

    6. Polymer Catalyst Preparation for Advanced Resins

    Producers of specialty polymers employ Ethyl Sulfuric Acid as a catalytic initiator in the synthesis of sulfonated resins and copolymers, particularly for ion-exchange and high-performance engineering plastics. Its catalytic properties enable selective sulfonation, determining the ion conductivity and mechanical attributes essential for resin end-uses in automotive, water treatment, and electronics. Feed rates and acid strength must be precisely regulated to mitigate color formation, chain scission, and unwanted by-product formation, underpinned by continual quality control.

    Industry compliance standards

    • ISO 9001:2015 (Quality management for polymer and resin manufacturers)
    • IEC 62321 (standards for chemical analysis of electronic material polymers)
    • Automotive OEM chemical substance requirements (e.g., GADSL)
    • UL 94 (test for flammability of polymeric materials, for end-use applications)

    Typical usage ratio

    • 0.6–4% by weight, based on total monomer content; varies to achieve specific sulfonation degree or crosslinking density required by resin formulation

    Downstream process integration

    • Injected during polymerization or functionalization stage within reactor vessels, typically under inert atmosphere, for production of sulfonated aromatic and polyether resins, prior to pelletizing and final processing

    Final product types

    • Ion-exchange resins
    • Pefluorosulfonated engineering plastics
    • Functionalized high-barrier packaging materials
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    Certification & Compliance
    More Introduction

    Ethyl Sulfuric Acid: Direct from the Manufacturer’s Floor

    A Practical Look at Ethyl Sulfuric Acid in the Modern Chemical Industry

    Chemical manufacturing rewards hands-on experience and a deep understanding of process nuance. Ethyl sulfuric acid stands out on our production lines for its role bridging organic and inorganic chemistry in everyday industry. For decades, our teams have followed every batch run and drum shipment, learning what makes this compound tick in actual applications. From blending rooms to reactor vessels, the truth always shows up where chemistry turns raw feedstock into products that work and last.

    What We Make and How We Make It

    Ethyl sulfuric acid, with the molecular structure C2H5OSO3H, comes out of our reactors under strict controls from start to finish. We maintain specific molarities and residual sulfur dioxide levels by real-time monitoring and careful addition of ethanol to sulfuric acid under controlled cooling and agitation. Each batch receives in-line conductivity checks. Whenever we clock purity above 98.5% and moisture far below most grades seen in imports, we know quality is up to par.

    Volume buyers often look for material in standard concentrations around 70% or higher. For niche synthesis or lab-grade requests, we tighten tolerance on impurities like diethyl ether and limit chloride levels below even stringent electronics standards. Our in-house labs tip us off to patterns in impurity levels, letting us swap to a different-grade base acid or modify distillation schedules mid-run for consistent specification. Every finishing team here keeps an eye on the translucency – a subtle visual check that’s saved us from more than one off-spec batch heading outbound.

    How Ethyl Sulfuric Acid is Used Every Day

    End-users working in organic synthesis come to us mainly for the ethyl sulfate ester function. It finds purpose where direct sulfonation feels too aggressive for a delicate molecule but a mild, controllable transfer is essential. In fine chemical manufacturing, it enters as a sulfonating agent for custom surfactant backbones, pharmaceutical intermediates, dye precursors, and stabilizers for rare polymer formulations. Our batches have supported enzymatic studies in research labs, acted as catalysts in alcohol modifications, and enabled selective alkylation steps where more common acids risk product breakdown.

    Clients making surfactants or additives see actual process results in clearer solutions, stable pH curves, and higher purity yields compared to switching in older products like sodium ethyl sulfate. When someone requests guidance, our technical team relies on firsthand rerun data and direct customer feedback rather than legacy literature alone. Repeated encounters over the years have shaped our approach: not every use fits the textbook. In certain synthesis, a smaller-scale run shows subtle performance boosts because batch-to-batch consistency in byproducts matters more than theoretical reactivity.

    What Sets Ethyl Sulfuric Acid Apart

    Manufacturing puts us in a unique position. We see how minor differences in physical and chemical properties make real-world impacts on customers’ downstream processes. Let’s get specific. Ethyl sulfuric acid stands apart from bulk mineral acids for offering targeted reactivity, giving manufacturers a handle for introducing a sulfate group without risking over-sulfonation or hydrolysis. This higher level of control reduces neutralization byproducts and improves selectivity in multi-step organic synthesis, something users notice across core sectors from agrochemical intermediates to flavors and fragrances.

    In comparison to sodium ethyl sulfate and diethyl sulfate, our acid delivers a much sharper pKa and eases certain purification steps for sensitive products. Sodium ethyl sulfate, often available as a byproduct or in lower-quality imports, carries along stoichiometric sodium that can complicate downstream reactions. Diethyl sulfate, a strong ethylating agent, raises serious health and handling challenges and fits fewer safe synthetic routes. Ethyl sulfuric acid occupies a niche – reactive, sure, but balanced and workable for controlled transformations.

    Our operators no longer treat this acid as a “poor cousin” of more mainstream reagents. Each year brings a fresh batch of custom synthesis requests. Customers experimenting with renewable feedstocks, moving away from halogenated chemistry, or optimizing microreactor conditions increasingly reach for ethyl sulfuric acid. We respond with technical support, tracking actual yields and formation of trace impurities, and we adapt shipment packaging to address everything from drum static to warehouse climate swings. The upshot: those choosing ethyl sulfuric acid reduce worker exposure risks (thanks to milder volatility and fewer hazardous breakdown products) and often see a lower regulatory burden in final product labeling.

    Material Handling and Reliability

    In manufacturing, talk gets cheap unless it matches real logistics. Our production shifts know the importance of tight sealing, dry storage, and careful drum loading. In practical terms, ethyl sulfuric acid requires less extreme cooling and corrosion precautions compared to some chlorinated or phosphated acids. Operators still – and always – use gloves and splash-proof eyewear. Our refilling lines have evolved to incorporate dustless coupling, cleaned and checked for cross-contaminants every cycle. Techs track each vessel’s journey by batch number, keeping mishaps at bay and building a long paper trail our partners rely on for audits.

    One overlooked advantage seen at the plant level comes in waste treatment. We remember the headaches caused years ago by acids that broke down into troublesome volatiles. In contrast, ethyl sulfuric acid, when neutralized correctly, forms simple inorganic sulfates and ethyl alcohol – straightforward for disposal or further use. This cleaner breakdown reduces the headaches for end-stage handling and fits most common chemical plant water treatment procedures.

    Quality Control from Reactor to Loading Dock

    No product escapes our lines without in-depth scrutiny. Our in-process analytical labs run GC, HPLC, and titration for every lot. This is not marketing; it saves us pain down the road. At times, a single off-color hint or trace non-conforming peak led to an overnight batch rework. Field-reported issues, such as unexpected turbidity or polymerization during customer use, launch joint troubleshooting. We collect feedback directly from plant chemists and troubleshoot by reviewing our own instrumentation logs, not just paperwork.

    We’re open about variability. Ethyl sulfuric acid, sensitive to both residual water and tiny shifts in ethanol purity, demands vigilance. We’ve discovered that “good enough” ethanol grades used by competitors regularly underperform. Using only high-grade base inputs, we invest in extra purification and quality monitoring, even if it trims margins. Decades in this industry make clear: no time is saved by pushing out inconsistent product. Instead, every shipment comes with a guaranteed analysis set and, if a buyer points to trouble, we dive in headfirst, not hiding behind standard specs or generic disclaimers.

    Feedback Loops: The Benefits of Staying Direct

    There’s confidence on a line where the same staff have worked for years. Long-term manufacturing carries habits you don’t find in distribution or trading houses. Stories circulate about process tweaks that improved shelf-stability, tidied up barge transfer, or solved yet another blend compatibility hiccup for a regular customer. We keep records long after legal requirements end, learning from returns, slow movers, and even rare crystal formation during warehouse holds.

    These lessons carry the product forward. When a research customer calls with special-phase requirements or lower-odor threshold needs, we run pilot batches matched to their spec. If one shipper requests vapor-barrier drums due to ocean transport risks, we work with them on design and logistics. Our best product solutions originated not from reading technical sheets but through actual field failures and creative fixes in partnership with users. This feedback builds confidence both ways – our teams know why properties matter, and buyers trust our experience.

    Price, Value, and Supply Security

    Cost pressures roll through every chemical market. Cutting corners on specification, safety, or service to meet a low quote usually ends up as false savings. From a plant’s perspective, downtime caused by off-grade material or variation in acid reactivity costs much more than a small per-kilo price adjustment. Over the years, our buyers consistently report savings in overall plant operations after switching to direct-manufacture supply, citing steadier yields, less troubleshooting, and more predictable downstream product characteristics.

    No matter the market cycle, our scale ensures both stable supply and consistency. In shortages, we squeeze extra throughput using our fully integrated ethanol and sulfuric acid base stocks. When demand spikes, we absorb overtime and pull in additional production staff rather than issuing generic excuses or shipping mixed-source drums. This commitment to reliability lets R&D teams plan multi-year projects, assures purchasing departments of on-schedule deliveries, and gives technical teams a product they know inside out.

    Supporting Cleaner Chemistry and Innovation

    Ethyl sulfuric acid represents a subtle shift for the industry. More companies now seek cleaner, more controllable transformations. Our acid allows upgrades to “greener” processes, where better-selectivity sulfonation means less waste, simpler separation, and, in many cases, less hazardous labeling overall. Sectors like custom synthesis, high-value additives, and even research pilot lines rely on this acid to bridge legacy chemistry with new regulatory and consumer expectations.

    Small differences matter. For producers aiming for low-residue or high-purity markets, switching to an acid grade sourced direct from a manufacturing origin means the difference between flagged batches and regulatory wins. Our own evolving standards answer both these needs and the on-the-ground realities – adapting process steps, choosing reagents by long-term performance, and always ready for “what if” troubleshooting.

    Research collaborations have produced tailored forms for specific reaction systems: ultralow moisture for electronics and cleanroom applications, additional filtration for catalyst-sensitive end-uses, or unique packaging for reactive prototypes shipped overseas. These tweaks come from years of dialogue across the supply chain. Accountability shows in every report sent with a shipment; each includes traceable figures back to lab runs and logged batch histories.

    Comparing Ethyl Sulfuric Acid across the Market

    Ethyl sulfuric acid on the open market often turns up with significant variability. Imports or repackaged blends sometimes carry trace elements stemming from slipshod procedures, leftover mixed esters, or plainly under-dried drums. Feedback over the years has taught us these shortfalls show up too late – unwanted color, clogging, or process setbacks miles from source. We’ve developed sorting protocols and vendor relationships that close these gaps before material ever leaves our gate.

    From a manufacturer’s viewpoint, direct quality oversight, ongoing R&D, and technical support are crucial. Whenever customers experience fouling, low yields, or odor contamination with competitor acids, we dig into their process data and mimic it in our own labs for diagnosis. We even send mobile technical teams onsite during large-scale run-ups. This hands-on troubleshooting cannot be offered by intermediaries or brokers because it demands process-level commitment and the infrastructure to back it up.

    The Bigger Picture: Ethyl Sulfuric Acid in Industry Growth

    As regulations continue tightening and consumer demand grows for safer, greener, and more reliable chemical building blocks, products like ethyl sulfuric acid play a growing role in industry evolution. Fine chemical makers, advanced materials teams, and specialty formulators all look for reliable partners as much as reliable molecules. Consistency, honest support, and steady attention to both compliance and process performance never go out of style in chemical manufacturing.

    The lessons learned from thousands of successful (and a few not-so-successful) batches inform every process tweak, every customer recommendation. The acid itself evolves in purity, handling, and usability—reflecting input not only from our own floor chemists but also from research labs, plant techs, and the practical realities of global shipping and regulatory change.

    Building Forward: Commitment Grows with Each Batch

    Every drum, tanker, and kilo offered under our name tells the story of a direct, engaged approach to chemical manufacturing. For us, ethyl sulfuric acid is not simply one more reagent on a price sheet—it is the result of a history of doing and improving, learning directly from every use and every partner. Down-to-earth, open, and accountable, our manufacturing journey keeps us answering phones, tweaking batches, and pushing for better – on the factory floor, in the lab, and wherever chemistry moves next.