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Ethyl isovalerate

    • Product Name Ethyl isovalerate
    • Alias Ethyl 3-methylbutanoate
    • Einecs 203-299-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    274484

    Cas Number 108-64-5
    Molecular Formula C7H14O2
    Molecular Weight 130.19 g/mol
    Iupac Name Ethyl 3-methylbutanoate
    Appearance Colorless liquid
    Odor Fruity, apple-like
    Boiling Point 127-129°C
    Melting Point -90°C
    Density 0.867 g/cm³ at 20°C
    Flash Point 24°C
    Refractive Index 1.396 at 20°C
    Solubility In Water Insoluble
    Vapor Pressure 5 mmHg at 25°C

    As an accredited Ethyl isovalerate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250 mL amber glass bottle with secure screw cap, labeled 'Ethyl isovalerate', hazard symbols, lot number, and safety information.
    Shipping Ethyl isovalerate should be shipped in tightly sealed containers, away from sources of ignition, heat, and incompatible materials. It must be handled in accordance with local, national, and international regulations for flammable liquids. Ensure proper labeling and documentation, and use suitable cushioning and ventilation during transport to prevent leaks or spills.
    Storage Ethyl isovalerate should be stored in a cool, dry, well-ventilated area, away from heat sources, open flames, and direct sunlight. Keep the container tightly closed and away from incompatible substances such as strong oxidizers. Use only approved containers, preferably made from glass or compatible plastics. Avoid prolonged exposure to air and moisture to maintain the chemical’s stability and quality.
    Application of Ethyl isovalerate

    Applications of Ethyl Isovalerate in Industrial Manufacturing

    As a direct manufacturer of Ethyl isovalerate with extensive experience in supply chain integration and batch consistency, we focus on its real-world adoption in several established downstream industries. Our technical collaboration with customers in these sectors enables us to provide high-purity material and application guidance that aligns with recognized compliance, processing, and end-product requirements.

    1. Food and Beverage Flavor Compounding

    Ethyl isovalerate sees instrumental use in flavor formula development for applications such as fruit-flavored beverages, confectionery, and bakery products. Its distinct fruity aroma profile supports authentic note delivery in citrus and apple flavors, and supports mouthfeel in certain candies. Flavor houses generally introduce our material as a top-note enhancer during the batch flavor compounding stage, taking purity and organoleptic impact into account for every formula iteration. Manufacturing teams titrate addition levels based on matrix type, regional regulatory thresholds, and flavor intensity targets.

    Industry compliance standards

    • Food Chemicals Codex (FCC)
    • EU Regulation (EC) No 1334/2008 on flavorings
    • US FDA 21 CFR part 172.515 (synthetic flavoring substances and adjuvants)
    • JECFA specifications (FAO/WHO Expert Committee on Food Additives)

    Typical usage ratio

    • 0.5–12 ppm in finished beverage bases, depending on product category and local regulation
    • 10–60 ppm in jelly, confectionery, and bakery premixes—adjusted according to desired aroma profile and ingredient declaration requirements

    Downstream process integration

    • Addition during flavor batch blending or premix formulation prior to final product pasteurization or baking cycle
    • Dispersed into syrup or emulsion base components before dilution or direct-pack filling

    Final product types

    • Clear and cloudy soft drinks
    • Fruit-flavored jelly candies
    • Hard candy and confectionery base
    • Ready-mix cake and pastry products with fruit notes

    2. Fragrance Formulation for Fine and Functional Perfumes

    Formulators in the personal care industry value Ethyl isovalerate for its capacity to impart mature, fruity, green, and slightly creamy notes, often used to bridge volatile and mid-base accords in fragrance compositions. Professional perfumers incorporate this compound during the concentrate blending stage, weighing its impact on volatility, stability, and final olfactory character. The material’s threshold and tonality demand precise dosing to maintain formulation compliance and safety for skin contact applications.

    Industry compliance standards

    • International Fragrance Association (IFRA) Standards
    • Cosmetics Regulation (EC) No 1223/2009
    • IFRA Code of Practice (global)
    • US FDA Title 21 CFR 700.13 (cosmetic safety)

    Typical usage ratio

    • 0.01–0.2% (100–2000 ppm) of total fragrance concentrate—specific to product type and intended sensory effect
    • Levels adjusted for leave-on vs. rinse-off personal care applications and IFRA restrictions for end-use scenario

    Downstream process integration

    • Incorporated during perfume oil or base fragrance concentrate blending prior to ethanol dilution or fragrance compounding
    • Tested in small-scale pilot runs and subject to accelerated stability and allergen screening

    Final product types

    • Fine fragrance EDT/EDP bases
    • Personal care scents (shampoos, lotions, shower gels)
    • Liquid and powder detergents with green-fruity notes
    • Household air freshener bases

    3. Pharmaceutical and Nutraceutical Flavor Masking

    Oral dosage form design frequently addresses palatability challenges posed by bitter or unpleasant-tasting actives. Development teams in this sector use Ethyl isovalerate in masking systems, optimizing dosage for organoleptic compatibility and regulatory-mandated intake limits. R&D teams introduce it at the intermediate or final flavoring stage, often as part of flavor masking blends within liquid syrups, suspensions, and chewable dosage forms. Each lot is validated for heavy metal, solvent residue, and microbiological compliance ahead of incorporation into finished goods.

    Industry compliance standards

    • Ph. Eur. (European Pharmacopoeia) flavor additive monographs
    • US FDA Inactive Ingredient Database (IIG)
    • Good Manufacturing Practice (GMP) guidelines: ICH Q7
    • China Pharmacopoeia (ChP) food flavoring segments

    Typical usage ratio

    • 0.05–0.25 mg/mL for oral syrups, adjusted to meet adult and pediatric dosing requirements
    • 0.01–0.1% w/w in chewable tablets or granules, factoring in maximum allowable daily intake

    Downstream process integration

    • Added during late-stage suspension compounding or flavor blend integration after active matrix formation
    • Evaluated in pre-formulation for compatibility and stability under pharmaceutical process conditions

    Final product types

    • Oral pharmaceutical syrups and suspensions
    • Chewable multivitamin tablets
    • Pediatric rehydration powder sachets
    • Effervescent nutraceutical blends

    4. Tobacco and E-Cigarette E-Liquid Flavoring

    The tobacco industry applies Ethyl isovalerate to improve the fruity, mild back-note of both traditional and next-generation nicotine products. Tobacco blend designers utilize the compound to round out harshness and build complexity in e-liquid and cigarette flavor systems. Formulators attend closely to industry-specific traceability and carryover restrictions, especially for products catering to regulated markets with detailed substance disclosure requirements.

    Industry compliance standards

    • ISO 24198 (Guidelines for e-liquids)
    • TPD (EU Tobacco Products Directive, Article 20 and Annex II)
    • US FDA Premarket Tobacco Product Application (PMTA) ingredient assessment (for e-cigarettes and vapor liquids)
    • GB/T 31115 (China e-cigarette liquid standard)

    Typical usage ratio

    • 1–30 ppm in tobacco blend sheets—balanced against regulatory and brand profile targets
    • 10–50 ppm in e-liquid concentrates; dose reversed for high- and low-nicotine formulas and device wattage

    Downstream process integration

    • Blended into tobacco sauce or casing stage for reconstituted tobacco preparation
    • Integrated at the concentrate mixing phase for e-liquids, prior to PG/VG dilution and bottling

    Final product types

    • Cigarette and cigar flavor top-notes
    • E-liquid and e-juice for open- and closed-system vaporizers
    • Heated tobacco product sticks or capsules
    • Tobacco flavor reconstituted sheets

    5. Animal Feed Palatability Enhancers

    Feed manufacturers use Ethyl isovalerate in palatability systems for specialty pet foods and certain farm animal feeds, aiming to encourage intake and mask off-flavors linked to novel protein sources or mineral supplements. Integration in flavor premixes or direct spray applications during pelletizing enables consistent aroma transfer through feed processing. Addition levels respond to target species consumption behavior and compliance with national veterinary feed additive listing.

    Industry compliance standards

    • EU Register of Feed Additives (Regulation (EC) No 1831/2003)
    • AAFCO (Association of American Feed Control Officials) flavor agent guidelines
    • China GB/T 7300.101 (feed additive flavoring)
    • Good Manufacturing Practice for Feed Additives (FAMI-QS Code)

    Typical usage ratio

    • 10–100 ppm in compound feed formulas—adjusted for palatability threshold per animal species
    • 20–200 ppm in semi-moist and wet pet food palatability coatings

    Downstream process integration

    • Blended into the feed premix tank before extrusion or pelletizing
    • Spray coated onto cooled feed pellets or dry kibble in post-processing stages

    Final product types

    • Compounded farm animal feeds (swine, poultry, ruminant)
    • Canned and semi-moist pet food
    • Dry kibble with enhanced aroma
    • Specialty treats for feed intake trials
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    Certification & Compliance
    More Introduction

    Ethyl Isovalerate: Origin, Benefits, and Our Approach to Manufacturing

    Introduction to Ethyl Isovalerate

    For decades, industries working with flavors, fragrances, and solvents have placed trust in ethyl isovalerate for its nuanced performance and reliability. With a fruity, apple-like character and low toxicity, this ester finds its way into countless everyday products, from fine fragrances and cosmetic blends to food and beverage formulations. Unlike bulk commodity chemicals, materials such as ethyl isovalerate often come with high expectations for both purity and reproducibility. As a long-standing chemical manufacturer, we have seen the market's demands shift, both in scale and specification. In response, we refined our manufacturing processes, ensuring each batch supports our customers’ end-use requirements, from rigid food standards to the subtlety required by perfumers.

    A Close Look at Our Ethyl Isovalerate

    Ethyl isovalerate is structurally defined as the ethyl ester of isovaleric acid. That underlying simplicity allows for versatility, yet the effectiveness always comes down to purity. Our standard model for commercial production refers to material with a purity of at least 99%. Typically, the distilled fractions do not carry strong off-notes or residual acidity, due to controlled temperature parameters and precise distillation techniques. Because esterification reactions can generate side-products, routine in-process analysis is built into every batch—a practice that shortens reworks and avoids contamination.

    With a molecular formula of C7H14O2 and a characteristic fruit aroma, ethyl isovalerate balances volatility and tenacity. That balance grants formulators the flexibility to provide top and mid-note profiles in flavors and fragrances, something not always possible with similar short-chain esters.

    Manufacturing Practice and Distinctive Methods

    Chemical synthesis always presents a crossroads for compromises: speed, cost, purity, and scalability are locked together. In manufacturing ethyl isovalerate, the goal remains constant — minimize unreacted acid, remove excess ethanol, and meet the exacting specifications of each client. Starting from pharmacopeia-grade feedstocks, our team applies catalytic esterification at controlled temperatures. Aging equipment or low-grade reactants can easily throw off flavor or manifest as trace acidity. Each month, our audit team samples process lines to ensure corrosion hasn't led to heavy metal carryover, an issue that can evade standard production checks. Downstream, we integrate an extra cold-polishing step for batches bound for fragrance and flavor houses, which removes high-boiling tars and helps avoid cloudiness or color instability during storage.

    Conventional suppliers sometimes see less value in custom runs, focusing instead on large-volume, least-cost output. We stand apart by scaling batch volumes to customer demand, whether it's a full ISO tank for an industrial client or demijohns for artisanal perfumers. Our approach brings clear advantages — rapid turnarounds for NPD (new product development) clients and consistent, traceable batches for large-scale finished goods.

    Applications Across Industries

    Ethyl isovalerate’s core application lies in food and beverage, where it satisfies both regulatory and sensory hurdles. Many global soft drink and confectionery brands include it in their formulations to impart a smooth, ripe fruit note without introducing instability or bitterness. Based on our work with flavor chemists, the low threshold of detection allows for efficient dosing. That means a few parts per million can provide a fresh character without cloying sweetness.

    Perfumers value ethyl isovalerate for its agile performance across both top and middle accords. Combined with heavier fruity esters, it creates a long-lasting, natural impression. From fruit bouquets to fantasy blends, years working alongside formulators have demonstrated that quality-of-source noticeably impacts the dry-down of fine perfumes. Even small levels of branched acetates, leftover from crude manufacturing processes, can undermine the olfactory profile and introduce unwanted harshness. By tailoring fractionation cuts to remove these volatiles, we help ensure subtle, round top notes that persist without diffusive sharpness.

    Solvent applications shape yet another sector for ethyl isovalerate. From specialty ink production to resin and coating modification, the ester’s low water solubility and high solvency power make it suitable for selective solubilization. Unlike many common ester solvents, ethyl isovalerate brings low reactivity toward alkali and fine pigment dispersions. In our own line, feedback from long-term industrial users led us to reduce peroxide-forming impurities, lessening risk and extending the shelf life for sensitive formulations.

    Performance Compared to Other Esters

    Many esters share a similar role as carriers of fruit and floral notes, yet the slightly branched structure of ethyl isovalerate brings clear differences. Compared to ethyl butyrate, which gives a sharp pineapple note, isovalerate exhibits less raw intensity and more rounded, apple-peach nuance. In flavor trials, these variations are easy to detect in blind sensory panels — experienced tasters frequently describe ethyl isovalerate as less volatile, with a smoother, more natural mouthfeel.

    In industrial solvent blends, ethyl isovalerate separates itself from acetates such as ethyl acetate or isopropyl acetate. Despite similar evaporation rates, isovalerate esters do not embrittle coatings and often remain less aggressive toward plasticizers and elastomers. Across multiple customer-led reformulations, we have seen that the switch to this material can resolve embrittlement complaints and improve application smoothness in solvent-based adhesives and specialty paints.

    Compared with methyl isovalerate — a close cousin — ethyl isovalerate shows reduced volatility and greater persistence in both sensory profiles and industrial use. In practical experience, this translates to better retention in food and beverage products during pasteurization or extended storage, and higher aroma yield in perfumed articles exposed to air.

    Quality Control and Batch Tracking

    One problem the industry often faces involves batch-to-batch variability. With esters, even modest changes in reactant purity or minor deviations in reaction time can shift aroma notes or introduce instability on storage. Our quality assurance program tracks every input lot, storing spectral and chromatographic data for cross-checks over several years. Technicians conduct a detailed GC-MS scan for every batch, flagging minor unknowns for follow-up review. It is not rare for customers to ask about a subtle off-note detected in a formulation test. Experience has taught us that early and complete traceability accelerates troubleshooting and protects downstream processes.

    While certifications attract regulatory attention, the most useful guarantee often comes from consistent supply. In recent years, clients reported disruptions from overseas sources linked to unannounced changes in process solvents or reagents. Our process audit trails document exactly when, how, and why any change occurs. Customers relying on certifications for kosher, halal, or allergen-free status need that data, especially when formulating for sensitive or global markets.

    Supply Chain and Packaging Options

    Ethyl isovalerate’s stability and resistance to hydrolysis grant it a long shelf life — provided the packaging and seals maintain integrity. Over the years, we found that solvent-grade poly liners, high-density polyethylene drums, and fluorinated containers preserve the product best, preventing absorption or migration of volatiles. Based on input from both multinational flavor houses and boutique studios, we now offer container sizes spanning laboratory packs, kegs, and bulk ISO tanks, with dedicated lots sealed to avoid cross-contamination.

    Clients formulating high-impact flavors or perfumery accords in small volumes benefit from customized pack sizes and rapid dispatch, especially when validating or upscaling new launches. With major industrial customers, our logistics teams manage just-in-time supply programs to limit storage hazards and waste. On-site audits, remote sensor data on warehouse climate, and barcode tracking help us respond quickly should a recall or urgent supply shift become necessary.

    Safety, Environmental Responsibility, and Industry Shifts

    Safe handling of ethyl isovalerate starts with solid process design. Its low toxicity and rapid biodegradability make it less hazardous than many solvents. Our storage policies reflect practical safety margins, including local eyewash stations, spill containment, and comprehensive staff training. Although the chemical has a low environmental impact when managed responsibly, small leaks or waste can create persistent odors. Years ago, the shift to closed transfer systems in our facility reduced emissions and improved workplace comfort — a change prompted by direct feedback from our plant floor staff.

    Customers attending to green chemistry and traceability require more transparency than ever before. We started adopting compliance with international chemical inventories ahead of mandate deadlines. In response to requests, all outgoing shipments carry updated safety data and recyclability guidance for containers. Where possible, we work with downstream partners to establish returnable drum cycles or local reconditioning, limiting single-use waste. Insights from LCA (life cycle assessment) studies conducted with clients frequently steer us toward process improvements, ranging from energy recovery during distillation to lighter secondary packaging for export.

    Facing Volatility and Regulatory Pressures

    Production schedules for esters such as ethyl isovalerate can get thrown off by swings in feedstock prices or regulatory hurdles. During spikes in ethanol and isovaleric acid costs, we drew on long-term supply agreements and strategically stored raw materials, making sure to smooth out sudden price surges for frequent buyers. Historically, recurring changes in flavor and fragrance additive regulations in the US, Europe, and East Asia mean we always stay ahead with regular compliance reviews, not just for the raw material but also for possible impurity carryover.

    Through decades in the field, customer reports have made it clear that sourcing reliability often makes the real difference, not just technical data sheets or marketing brochures. Manufacturers in food and fragrance routinely experience supply gaps when regulatory limits shift or trade policies block imports. Since we control our entire synthesis chain, we can adapt rapidly to new regulatory guidance, from adjusting the use of catalysts to switching to bio-based ethanol if needed. For example, the increasing demand for non-GMO, natural-identical flavors led to production runs based on natural-source ethanol, accompanied by full chain-of-custody documentation.

    We keep a close watch on updated REACH, TSCA, and JECFA rulings regarding maximum residue limits and authorized uses. If an impurity profile gets flagged by a regulatory body, our teams collaborate with customers to analyze the affected batches, provide alternative lots, or adjust purification. Years of technical exchange have shown that open communication between producer and formulator quickly resolves crises that could take weeks or months if handled through layers of intermediaries.

    Collaboration with Customers

    Our process rarely ends with shipping drums from the loading dock. Formulators and technical buyers come back to discuss performance at commercial scale. We receive routine field data about how ethyl isovalerate behaves in new bases, direct feedback that leads us to tweak fractionation or purification steps. Often it’s subtle: a shift in top note balance or a minor haze developing in a beverage. By being available for batch-specific troubleshooting, our technical team builds lasting trust with customer R&D labs.

    Innovation often begins at the intersection of supplier and user experience. Several clients with unique project requirements have pushed us to trial alternative catalysts or modified temperature curves, always backing the process with analytical data and sensory review. Rapid prototyping in small-scale reactors accelerates time-to-market for challenging new flavor accords or targeted industrial coatings. Our willingness to experiment at small scale, then support rapid scale-up, means our clients can develop and launch differentiated products without taking on unnecessary risk or cost.

    Feedback cycles, both formal and informal, drive our improvement plans. Years of partnership have taught us where the bottlenecks and sticking points lie in real-world use. Being on hand to advise or tweak supply methods—sometimes with a fifty-liter pilot lot, sometimes with a full container load—ensures mutual growth and keeps product development moving forward.

    Adapting to Sustainability and Market Trends

    Global awareness around the environmental impact of chemical manufacturing keeps growing, especially among customers formulating for organic, clean-label, or vegan end markets. To meet this challenge, our plant engineers introduced closed-loop systems that recover and recycle heat from the esterification process, cutting both energy consumption and emissions. Sourcing bio-based raw materials became a core part of our procurement strategy, with annual reviews of supplier certification and traceability. Customers aiming for third-party environmental certifications rely on these documented practices for their own compliance audits.

    Recent shifts in consumer preference toward natural flavors sparked increased demand for fermentation-derived esters. While synthetic production remains the dominant approach, we have built pilot programs to support clients requiring natural labelling, leveraging our long-standing relationships with fermentation specialists. These efforts allow clients to launch ‘flavor from natural sources’ lines without abandoning the performance or batch-to-batch consistency they are used to from synthetic routes.

    In the field of technical solvents, increased scrutiny about workplace exposure and downstream emissions led to the development of low-odor, purified ethyl isovalerate grades. These meet stricter workplace safety limits and improve the work environment for users applying the material in enclosed settings. Regular dialogue with regulatory consultants and customer safety officers helps us anticipate new standards and innovate well before new rules take effect.

    Building Trust Through Experience and Shared Success

    Reliability and direct technical support set the difference between lasting supplier relationships and one-off purchases. Decades of hands-on experience manufacturing ethyl isovalerate give us a practical understanding of its behavior at every point—from raw material through processing, packaging, shipping, and application. We have weathered raw material crises, regulatory upheaval, and demand surges, always keeping direct lines of communication open with clients. That continuous improvement loop—listening, analyzing, adapting—keeps manufacturing responsive, accurate, and sustainable.

    With each batch we send out, we carry forward not just a product, but years of applied know-how and customer partnership. Through collaboration, transparency, and a commitment to meeting evolving needs, we support enterprise-scale and small-batch projects with the same dedication. Ethyl isovalerate stands as more than a molecule in a catalog; through careful manufacturing and transparent partnership, it earns its place in top-performing flavors, fragrances, and technical solutions worldwide.