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Ethyl isobutyrate

    • Product Name Ethyl isobutyrate
    • Alias Ethyl 2-methylpropanoate
    • Einecs 203-293-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    519888

    Cas Number 97-62-1
    Molecular Formula C6H12O2
    Molecular Weight 116.16 g/mol
    Appearance Colorless liquid
    Odor Fruity, characteristic odor
    Boiling Point 102-103 °C
    Melting Point -90 °C
    Density 0.867 g/cm3 at 20 °C
    Flash Point 17 °C (closed cup)
    Solubility In Water Insoluble (approx 0.15 g/L at 20 °C)
    Refractive Index 1.387-1.389 at 20 °C
    Vapor Pressure 30 mmHg at 25 °C

    As an accredited Ethyl isobutyrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Ethyl isobutyrate is packaged in a 500 mL amber glass bottle with a secure screw cap and hazard labeling.
    Shipping Ethyl isobutyrate is shipped in tightly sealed containers, typically drums or glass bottles, and stored in a cool, well-ventilated area. The chemical is flammable, so it must be kept away from heat, sparks, and open flames. Appropriate hazard labeling and transport regulations, such as UN 1175, must be followed during shipping.
    Storage Ethyl isobutyrate should be stored in a cool, dry, well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep the container tightly closed and protected from physical damage. Store separately from strong oxidizing agents, acids, and bases. Use approved containers made of compatible materials to prevent leaks or contamination, and ensure proper labeling for safety.
    Application of Ethyl isobutyrate

    Applications of Ethyl Isobutyrate in Industrial Manufacturing

    Ethyl isobutyrate is an established specialty ester valued for its distinct fruity aroma, stability, and compatibility across targeted industrial sectors. We supply material with fully traceable quality and batch consistency, optimized for use in downstream applications that demand regulatory compliance and precise formulation performance.

    1. Food Flavor Formulation

    As a key fruity flavoring agent, ethyl isobutyrate plays an essential role in formulating compounded flavors for beverages, confectionery, and dairy analogs. Its stable volatility profile and intense pineapple-like note allow fine-tuned flavor systems that must deliver sensory impact without masking base components. Flavorists leverage its blending power to engineer authentic taste profiles and consistent product experience under strict food safety requirements.

    Industry compliance standards

    • Codex Alimentarius (FAO/WHO) – General Standard for Food Additives (GSFA)
    • European Commission Regulation (EC) No 1334/2008 for flavorings
    • US FDA 21 CFR §172.515 (Flavoring substances and adjuvants)
    • Food Chemicals Codex (FCC) purity criteria

    Typical usage ratio

    • 0.5–35 ppm in beverages; 5–40 ppm in confectionery; 2–25 ppm in dairy flavors—formulators set final dosage based on base recipe, target flavor intensity, and regional regulations.

    Downstream process integration

    • Introduced during aqueous or oil-phase blending of compounded flavors; post-pasteurization addition in clear beverage production lines; mixing into melted confectionery mass prior to forming, or added to dairy emulsions before UHT treatment.

    Final product types

    • Carbonated soft drinks, fruit juices, hard candies, gummies, yogurt flavors, ice cream bases, bakery fillings

    2. Nicotine E-liquid Manufacturing

    Ethyl isobutyrate imparts clean, fruit-driven top notes in nicotine-containing e-liquids for vape applications. Its low reactivity and high organoleptic purity support clear, stable end formulations, directly affecting consumer acceptance in highly regulated markets. Liquid compounding departments rely on its compliance with inhalation safety standards and its ability to boost multi-layered flavor profiles.

    Industry compliance standards

    • ISO 8317 (Child-resistant packaging for e-liquid products)
    • EU Tobacco Products Directive 2014/40/EU flavorings restrictions
    • AFNOR XP D90-300-2 (France) – E-liquid composition and purity
    • US Food and Drug Administration (FDA) Deeming Regulation compliance for vape product ingredients

    Typical usage ratio

    • 0.01%–0.09% of e-liquid mass, with precise adjustment during bench validation to prevent overpowering other flavor ingredients and ensure compliance with regional flavoring limits.

    Downstream process integration

    • Used during the cold blending of PG/VG base systems after nicotine dilution step; compounded as part of finished e-liquid premixes before sterile filtration and fill/finish operations.

    Final product types

    • Fruit-flavored nicotine e-liquids, pod-based vape cartridges, open-system e-juice refills

    3. Pharmaceutical Syrup and Oral Suspension Flavors

    In oral pharmaceutical liquid preparations, ethyl isobutyrate serves as both a palatability enhancer and a masking agent for unpleasant active ingredients. Stringent impurity control and batch-to-batch uniformity are essential to pass pharmaceutical release testing, as flavor consistency critically impacts patient compliance in pediatric and geriatric formulations.

    Industry compliance standards

    • Ph. Eur. 10.0 (European Pharmacopoeia) general monographs on flavoring agents
    • USP-NF monographs relevant to excipients
    • ICH Q3C (R8) guidelines for residual solvents and excipient safety
    • GMP – EU Guidelines for Medicinal Products for Human Use, Annex 8

    Typical usage ratio

    • 5–30 ppm in oral liquids, typically established through taste panel trials and QbD studies to achieve optimal palatability without exceeding pharmacopoeial thresholds.

    Downstream process integration

    • Incorporated as a flavoring agent during final compounding of syrup or suspension bases; added post-filtration under GMP-controlled blending, followed by immediate packaging to prevent volatility losses.

    Final product types

    • Antitussive syrups, pediatric antibiotic suspensions, electrolyte oral solutions

    4. Fine Fragrance Compound Production

    Perfumers incorporate ethyl isobutyrate in the creation of modern fragrance accords, especially to recreate fresh tropical fruit top notes or functional consumer product scents. It provides unique volatility and aroma diffusion in both alcohol-based fine fragrances and functional scents for home care or personal care end products. Material transparency and impurity specification are critical to avoid unwanted olfactory notes and regulatory issues.

    Industry compliance standards

    • International Fragrance Association (IFRA) Standards for ingredient usage levels
    • EU Cosmetics Regulation (EC) No 1223/2009, Annex II–V for ingredient registration
    • REACH (EC) No 1907/2006 chemical registration for supply into the European Union
    • ISO 9235:2013 for definitions and purity requirements in fragrance raw materials

    Typical usage ratio

    • 0.01%–0.12% in perfume compounds; 0.003%–0.09% in home fragrance bases; dosage is set by olfactory trials and IFRA maximum exposure calculations for each end use.

    Downstream process integration

    • Added during the blending of top note fractions in concentrated perfume production; included in masterbatch creation for functional fragrance applications prior to alcohol dilution, compounding, and quality assessment via GC-MS and panel testing.

    Final product types

    • Fine fragrances (EDP/EDT), fabric refreshers, reed diffusers, scented candles, air fresheners

    5. Aromatic Solvent and Industrial Cleaning Agent Manufacturing

    In specialty industrial cleaning fluids and aromatic solvent blends, ethyl isobutyrate brings a characteristic fruity masking odor, allowing downstream manufacturers to reduce the perception of harsh chemical notes while maintaining solvent efficacy. This application requires chemical and workplace safety compliance, as well as tight control of evaporation rates and compatibility with other blend components.

    Industry compliance standards

    • OSHA Hazard Communication Standard (29 CFR 1910.1200) for labeling and SDS
    • Directive 2004/42/EC (EU VOC Solvents Emissions Directive)
    • NIOSH/ACGIH workplace exposure guideline adherence
    • ASTM D235-02 standard for mineral spirits and odorized solvents

    Typical usage ratio

    • 0.01%–0.3% by volume in industrial cleaning formulations—blenders adjust to match odor-masking impact and avoid excessive volatility in final use.

    Downstream process integration

    • Incorporated during bulk blending of multi-component solvent systems in closed mixing tanks, usually after the introduction of principal solvents and before inerting or packaging operations.

    Final product types

    • Odor-masked industrial degreasers, specialty cleaning solutions for electronics, solvent blends for laboratory and workshop use

    6. Animal Feed Flavor Enhancer Production

    Feed and premix manufacturers use ethyl isobutyrate as a high-impact palatability additive to improve voluntary feed intake in young livestock. It provides a detectable fruity aroma that masks undesirable base feed odors, supporting improved weight gain and feed conversion ratios. All use must conform to animal feed ingredient legislation and ensure absence of carry-over residues.

    Industry compliance standards

    • EU Regulation (EC) No 1831/2003 on feed additives
    • AAFCO feed ingredient definitions (US)
    • China GB 7300.101-2019 (feed additive safety and hygiene)
    • HACCP feed production certification

    Typical usage ratio

    • 0.3–6 ppm in complete feed mixes; dosage depends on animal species, age, and base feed profile as established by feed flavorist trials.

    Downstream process integration

    • Dry-mixing into vitamin-mineral premixes or liquid spraying onto pelleted feeds post-conditioning, immediately before cooling and packaging to retain aroma intensity.

    Final product types

    • Starter and grower feeds for piglets and calves, flavored mineral blocks, high-palatable specialty animal feeds
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    Certification & Compliance
    More Introduction

    Introducing Ethyl Isobutyrate: A Genuine Blend of Performance and Reliability

    Real-World Experience with Ethyl Isobutyrate

    Getting hands-on in chemical manufacturing means seeing every raw material with a critical eye. I've watched how a batch of Ethyl isobutyrate can transform the aroma profile in a flavor house, or lock in high-value characteristics in specialty coatings. This clear, colorless liquid carries a distinctive, fruity scent that stands out in both fragrance and flavor markets. Customers rely on us for consistent composition and narrow range of impurities. Every shipment from our tanks represents months of refining process parameters based on direct feedback from customers who pour, mix, distill, blend, and analyze dozens of batches each month. I can tell you that when a perfumer or food technologist calls us twice in a row, impressed by the vibrant, sweet character of the latest drum, this is direct proof of process control paying real dividends.

    How Ethyl Isobutyrate Fits: Key Specifications from the Plant Floor

    We work with a high-purity standard—no less than 99% by GC—because we know just a trace of the wrong impurity can alter a product profile. Moisture sits below 0.1%, which means bakers, confectioners, and beverage formulators don’t end up fighting haze or off-notes in their end products. Specific gravity and refractive index are tested daily. Our technicians don’t just hit checkboxes: they trust those numbers to predict performance in hundreds of flavors, due to how even small deviations can throw off solubility or shelf stability. Typical fragrance users talk of how low-acid residues and stable esters prevent unanticipated changes in perfume batches, where subtlety is everything. Long story short, we test more frequently than any regulatory framework requires, not to tick boxes but to make sure downstream users don’t hit surprises.

    Practical Uses—Drawing from Years on the Production Line

    Ethyl isobutyrate has found an enduring home in foods, beverages, and flavors. Any time you pull the cap off a pineapple soda and catch that juicy note, there’s a decent chance the backbone comes from a carefully weighed measure of our ester. Distillers rely on our product to fine-tune complex aromatic notes in both spirits and non-alcoholic drinks. Confectionery teams reach out, chasing those bright, tropical notes that keep finished sweets lively and consistent. Over the years, I’ve seen our product pressed directly into chewing gums, lollipops, and even dairy products like yogurts and flavored milks. Even when dosage sits at parts per million, the impact jumps out. And it goes well outside food. Paints and coatings sometimes make use of ethyl isobutyrate as a scenting agent, helping reduce or mask harsh base chemical odors. Household products and personal care lines pick it up to add a bright, natural top-note. It’s versatile enough that regulatory bodies across multiple regions have built clear monographs for its use.

    What stands out to me is the scale: from family-run candy works to global soft drink bottlers, the conversations always come back to traceability and consistency. When someone calls our line asking about a shipment, I know they want more than a generic solvent—they want a reliable, reproducible effect every time, whether their plant is in Europe, North America, or across the Pacific.

    What Sets Our Ethyl Isobutyrate Apart: Not All Esters Compare

    A lot of people look at esters and see only broad categories; they miss the little chemical quirks that separate winners from the rest. Ethyl isobutyrate’s unique fruity, pineapple-forward aroma outperforms related esters like ethyl butyrate or methyl isobutyrate, which might bring harsher, less natural notes. In our labs, we’ve compared the olfactory profiles side by side for global flavor houses. Ethyl butyrate, for all its utility, often comes across as too sweet or “candy-like,” missing the subtlety our clients seek for authentic fruit tones. Methyl isobutyrate, on the other hand, tends toward a sharper, solvent character—less forgiving in flavor blends and much harder to mask in fragrance applications.

    Chemical stability matters, especially during long-haul shipments or temperature swings. Some esters degrade or hydrolyze far faster, leading to shifting profiles and unpredictable end results. Our product, made in closed-system reactors, maintains aromatic sharpness whether shipped to a cold northern warehouse or a hot equatorial bottling line. Feedback loops from users lead us to adjust purification methods. We run additional distillations or upgrade column packing. That way, someone opening a container anywhere in the supply chain gets the same crisp result, batch after batch, year on year.

    Production, Purity, and Longevity—Built on Daily Practice

    Producing reliable ethyl isobutyrate takes more than an off-the-shelf recipe. Considerations begin with raw material sourcing. Every tank of butyric acid and ethanol must pass purity screens designed by our own R&D—no margin for risk. Reaction conditions, such as temperature control and acid catalyst dosing, are set based on decades of trial runs and process data. Cooling rates contribute as much to final flavor as distillation speed. Chemical plants never run on autopilot; operators watch every variable hour by hour. After esterification, purification steps target color, turbidity, and trace by-products, since even faint yellowing will make sensitive flavor buyers look elsewhere. Years ago, we learned the hard way just how seriously confectionery contracts treat color and clarity.

    Regular feedback from end users led us to reduce residuals far below what’s set in compendia like FCC or JECFA. More than once, a sharp-nosed flavorist caught trace sulfur notes, pushing us to find the tiniest leaks in the closed-loop distillation system. These adjustments might seem minor in the scheme of an industrial plant, but they make big differences for clients who live by their palate. Every time we update a process, it’s because a batch somewhere didn’t meet expectations—so we go back, find the problem, and lock in the improvement.

    Regulatory and Quality Considerations

    Long-term partners know that keeping up with shifting food safety, import, and transportation rules is as critical as the ester itself. Ethyl isobutyrate earns spots in foodstuffs, carries FEMA GRAS status in the United States, and sits in clear positive lists across Europe and Asia. We document every origin point, every purity test, and each production batch as standard practice. Auditors walk through at random; we treat every day as if they might show up. The real importance of documentation becomes obvious during a recall in a different product line—our traceability procedures stop confusion cold, keeping both us and our clients protected from regulatory trouble.

    Some buyers need more than flavor purity; they require allergen-free declarations, tailored packaging, or specific certifications, such as kosher or halal. These aren’t boxes for us: they reflect sustained dialogue with every major segment we serve, from drink mixers in Latin America to bakery giants in Europe. We field questions about new regulatory definitions and handle changes in food migration testing without skipping a beat. Losing track risks entire national contracts; long-term bonds rely on us doing the homework today, so others don’t pay for pains tomorrow.

    Packaging and Handling: Experience from the Loading Dock

    We choose drums, IBCs, or bulk tankers based on decades of real shipping data. Many fragrance buyers demand UN-approved containers to meet local transport laws. Our packing line trains for zero cross-contamination; one careless loadout easily totals a shipment for an exacting client. Storage guidance comes from the reality of field conditions, not textbook scenarios. Warehouse staff across climates ask about minimizing hydrolysis, maximizing aroma over time, and reducing air ingress in opened containers. We use our experience to strike a balance between cost, safety, and shelf life. More and more clients ask about recycling codes and container reuse—a change we noticed before most city ordinances even caught up.

    Drummed product enjoys a shelf life of at least 12 months in cool, dry conditions, but we encourage frequent lab re-analyses for older inventory. Some clients push for extended shelf life, others prefer just-in-time deliveries. Our job is keeping both happy by documenting batch performance over time, ready to troubleshoot the moment something seems off. Real use cases across continents feed back into how we pack, label, and move every batch. These details are not theoretical—they make the difference between a working production line and a costly plant shutdown.

    Supporting the Industry—Beyond Just Sell and Ship

    Being a manufacturer in a global industry means seeing trends before they show up in procurement data. We’ve identified shifts as beverage brands adjust formulations to lower sugar content, which impacts the baseline of high-fruitiness esters like ours. Confectionery trends have led more brands to “natural flavorings,” which sometimes asks for non-synthetic labeling. We answer by running side-by-side comparisons in pilot plants, documenting differences in aroma threshold, solubility in modern bases, and side-flavor masking. Sometimes, a food scientist will come to us with a puzzling interaction involving pH swings or acidulant choices; we jump in with bench-scale tests, logging exactly how ethyl isobutyrate behaves, so users get straight answers. Field results matter vastly more than theoretical specs, and practical support is only possible by ongoing collaborative work.

    Even in pandemic years, supply chain pressure forced changes in batch scheduling, feedstock selection, and transportation. We prioritized the most affected industries, supplied flexible pack sizes, and adjusted lead times to minimize disruption to critical lines like hospital nutrition and formulated hygiene products. If a new transport regulation hits, we change schedules or packaging within weeks. This flexibility didn’t come from a crisis-management manual—it’s the result of listening and adapting, day after day, for decades.

    Troubleshooting and Solutions: Hands-On Experience Shared

    Nothing substitutes for the long-term memory built from direct troubleshooting. I recall times when a distributor called about an uncharacteristic cloudiness, and a real investigation revealed issues upstream in a supplier’s tank cleaning—which we jumped to fix. Other times, batch quality flagged due to overlooked valve seals or unexpected tank heating. Each event spawned a root-cause review that resulted in process change, not just a written report. Years of tracking these events led us to overhaul tank lining inspections and demand tighter calibration on blending lines. The goal isn't theoretical perfection, but robust reliability, so field operators never deal with billing disputes or off-note product returns.

    Flavor creators lean on our direct data sets, whether for shelf-life extension, cross-country shipping, or product adaptation for new government labeling requirements. We don’t just reply with a data sheet; if an issue crops up, we tap into archived historical runs, look for pattern shifts, and send technical staff to the client if needed. Even small improvements—eliminating a minor contaminant, retuning an anti-static spray formulation, or tweaking shipment scheduling for summer heat—translates into years of repeat business based on trust, not just price. Many of our mid-level customers eventually grew into market leaders, and still stick with us because they remember the support that solved a minor, yet costly, issue in their early days.

    Environmental and Social Accountability: Manufacturing for Tomorrow

    Manufacturers have a front-row seat to both the benefits and the baggage of chemicals in daily life. Ethyl isobutyrate has a relatively simple life cycle compared to some high-volume solvents, but every year brings new challenges. We minimize emissions at source, not as a line item, but because our work happens in communities surrounded by real families. Switches to closed-loop loading and recovery units stemmed as much from neighbor pressure as from regulation. Water treatment and off-gas controls improved because our own staff didn’t want to answer for avoidable nuisance odors at home.

    Today’s buyers also ask about renewable feedstocks and carbon impacts. We’re following bio-based ethanol and butyric acid sources, piloting runs to match performance before scaling up. Measuring carbon footprints isn’t just a boardroom trend—it shows up in multinational ingredient shortlists, and we want to get it right. Setting up external audits allows us to catch oversights that might slip through internal review. Documentation and progress updates flow as naturally as lab reports at this point, and we respond openly about strengths and limitations.

    Safety sits at the foundation of every batch. We never cut on PPE or overlook operator safeguards, as every recordable incident means not just paperwork, but a coworker suffering for a process shortcut. Building sustainable workplaces ensures low attrition and steady experience growth—inevitable wins for both product quality and company morale.

    The Human Side of Global Supply Chains

    It’s easy to talk about esters, yields, and purity data. Far more of our daily effort focuses on people. Keep relationships close—raw material suppliers, haulers, flavor blenders, plant engineers—because every one plays a key role in getting ethyl isobutyrate into finished products safely and reliably. I know technicians on our lines who have caught process upsets before a single drum left the gate. Freight coordinators flag route changes in hurricane season, keeping customer lines running without delay. Our lab team fields midnight calls for emergency specifications so urgent shipping can proceed next day.

    Clients don’t stay with us for theoretical expertise—they stick because our teams answer their calls, admit problems quickly, and make things right. That’s real experience talking. We build trust by sending field-tested support, rapid samples for approval, and back that up with concrete corrective actions. Maybe other plants do it differently. This approach comes straight from hands-on practice over years, linked by a real sense of mutual dependency from process water to finished bottle.

    Ethyl Isobutyrate—Worth the Care and Investment

    To anyone using or evaluating ethyl isobutyrate, know that manufacturing quality here isn’t a trade secret—it’s mostly the result of everyday work, honest feedback, and always striving for better. Every drop not only passes through reactors and pipes, but through the collective scrutiny of clients, regulators, and experts. Choices made in plant rooms can enable someone halfway around the world to mix a better beverage, bake a more appealing sweet, or create an aroma that sells millions of bottles.

    We put forward our ethyl isobutyrate after long-running focus on repeatable results, suitability for multipurpose applications, and support that doesn’t quit at the sale. Those who use it gain not just a chemical, but a partnership grounded in real-world experience from the first batch to the last drum on the lot.