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Endrin Ketone

    • Product Name Endrin Ketone
    • Alias Ketone, Endrin
    • Einecs 205-049-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    205468

    Chemical Name Endrin Ketone
    Cas Number 53494-70-5
    Molecular Formula C12H8Cl6O
    Molecular Weight 386.92 g/mol
    Appearance White crystalline solid
    Melting Point 245-246°C
    Boiling Point Decomposes before boiling
    Solubility In Water Insoluble
    Density 1.75 g/cm³
    Synonyms 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalen-3-one
    Un Number 2761
    Storage Conditions Keep in tightly closed container, store in a cool, dry, well-ventilated area
    Stability Stable under recommended storage conditions
    Uses Metabolite of endrin, research chemical

    As an accredited Endrin Ketone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Endrin Ketone is packaged in a sealed 500g amber glass bottle with a secure screw cap, labeled with hazard warnings.
    Shipping Endrin Ketone should be shipped in tightly sealed containers, clearly labeled, and protected from physical damage. It must be kept away from incompatible substances and stored in a cool, dry, well-ventilated area during transport. Comply with all applicable local and international regulations for hazardous chemicals during shipping.
    Storage Endrin Ketone should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Keep it away from direct sunlight, heat, and sources of ignition. Storage should be within a secure chemical storage cabinet labeled for toxic and hazardous substances, and access should be restricted to trained personnel only.
    Application of Endrin Ketone

    Applications of Endrin Ketone in Industrial Manufacturing

    Our production of Endrin Ketone supports specialized sectors that demand consistent quality, traceable sourcing, and strict alignment with global standards. We serve selected downstream markets where Endrin Ketone’s characteristics meet industry-specific formulation and regulatory requirements.

    1. Restricted-Use Agricultural Insecticides

    Agricultural chemical producers utilize Endrin Ketone in the synthesis of legacy insecticide formulations for niche crop protection scenarios under controlled regulatory exemption or government contract, where technically justified. The material facilitates the synthesis of agrichemicals acting on hard-to-control pest populations resistant to alternative chemistries. Companies undertaking these projects work within legacy framework programs, guided by authorities mandating comprehensive stewardship, traceability, and operator protection protocols, with production limits strictly enforced.

    Industry compliance standards

    • Regulation (EC) No 1107/2009 (EU restrictions on PPPs)
    • US EPA Restricted Use Pesticide (RUP) Classification
    • FAO/WHO International Code of Conduct on Pesticide Management
    • Good Laboratory Practice (GLP) for active ingredient synthesis

    Typical usage ratio

    • Up to 0.2% by weight in technical concentrate grade; actual content is batch-specific and strictly controlled due to regulatory risk assessment; small upscaling batches only with clear governmental rationale

    Downstream process integration

    • Introduced as an intermediate during the upstream synthesis of end-use active ingredients for insecticidal formulations; final blending and post-processing handled within secured, segregated facilities to prevent cross-contamination

    Final product types

    • Niche technical insecticide concentrates for target-specific vector control operations
    • Institutional-use pest management formulations for agricultural research and containment

    2. Reference Material for Analytical Standards Producers

    Certified reference material manufacturers employ Endrin Ketone as an essential component in the preparation of analytical standards for method calibration and laboratory proficiency testing. Such standards assess instrument performance in trace environmental monitoring, residue analysis, and forensic applications. Controlled production and dedicated documentation ensure traceable supply and precise characterization, supporting national and international laboratory networks in maintaining method accuracy and regulatory reliability.

    Industry compliance standards

    • ISO 17034 (General requirements for the competence of reference material producers)
    • ISO/IEC 17025 (Testing and calibration laboratory competence)
    • US EPA Method 8270 (Semivolatile organic compounds by GC/MS)
    • EN 15662:2018 (GC-MS/MS multiresidue analysis in food)

    Typical usage ratio

    • Microgram to milligram scale dilutions (i.e., 1–100 ppm in solution); precise amount calibrated to match target analyte concentrations within the relevant regulatory detection thresholds for each analytical application

    Downstream process integration

    • Dissolved into certified solvent matrices as part of multi-analyte calibration mixes or single-component reference solutions, often under strictly controlled ISO class conditions

    Final product types

    • Analytical standard solutions for chromatography calibration
    • Proficiency test kits for regulatory laboratories
    • Quality control reference sets for instrument manufacturers

    3. Governmental Environmental Monitoring Reagents

    Regulatory bodies and contract laboratories use Endrin Ketone in standard solutions for calibration, verification, and method validation during environmental contaminant monitoring. Its unique chromatographic properties make it valuable for instrument tuning and detection limit verification. Supply is reserved for laboratory-only application, as commercial trade or field use of the raw material remains heavily restricted by international law.

    Industry compliance standards

    • US EPA SW-846 (Test Methods for Evaluating Solid Waste)
    • ISO 6468 (Water quality—Determination of organochlorine pesticides)
    • EN ISO 17025 (Analytical quality assurance in environmental labs)
    • National metrology institute (NMI) traceability protocols

    Typical usage ratio

    • Typically 0.1–10 mg/L in calibration solutions; exact concentration adjusted to instrument linearity, analyte extraction efficiency, and relevant regulatory guidance

    Downstream process integration

    • Added to solvent matrices in analytical laboratory settings at initial standard preparation stage, followed by aliquoting into instrument-specific calibration vials

    Final product types

    • Tuning mixes for GC-ECD, GC-MS, and GC-MS/MS
    • Internal calibration standards for wastewater, soil, and food residue analysis

    4. Chemical Toxicology Research Compounds

    Pharmaceutical and toxicology research centers procure Endrin Ketone as a test chemical for in vitro and in vivo toxicological profile investigation. Researchers rely on tightly controlled grade supplied with documented batch traceability for accurate exposure-effect experimentation. Application domains cover mechanistic studies of organochlorine impact on biological systems, metabolic pathway elucidation, and method development in academic and regulatory science. Laboratory utilization complies with stringent substance handling, personnel safety regulations, and authorized project controls.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals (Section 4: Health Effects)
    • Good Laboratory Practice (GLP) Certification
    • Institutional Review Board (IRB) or Ethics Committee Approvals for animal/human toxicological research
    • Local chemical hygiene plans (CHPs) and laboratory biosafety level requirements

    Typical usage ratio

    • Dose preparation varies from 0.001–10 mg/kg depending on study design, species, and experimental endpoints, with final concentration or mass precisely calculated per protocol and safety oversight

    Downstream process integration

    • Prepared as accurately weighed aliquots or stock solutions for direct administration, tissue exposure, or metabolic transformation assays, always under controlled access and disposal regimes

    Final product types

    • Protocol-specific test solutions
    • Exposure kits for controlled laboratory bioassays
    • Metabolite reference materials for toxicokinetic profiling
    Free Quote

    Competitive Endrin Ketone prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Endrin Ketone: A Closer Look from the Factory Floor

    What Sets Endrin Ketone Apart

    At our production facility, Endrin Ketone has been a mainstay for years, trusted by agricultural chemical formulators who require consistency and precision. Recognizing the shifts in international regulatory landscapes and tighter scrutiny around organochlorine compounds, we take extra care in how we craft and control the quality of every batch. Unlike general-purpose solvents or broad-spectrum intermediates, Endrin Ketone belongs to a very focused class of chemicals. Its formula—C12H8Cl6O—features a distinctive structure that gives it particular utility in synthesis and pest control research.

    Our personnel have extensive experience refining the process parameters to achieve narrow specification ranges. We keep the purity at or above 98% by GC, targeting impurities below 1%. Moisture control remains a critical step. Small increases can lead to unwanted by-products, so we continuously invest in analytics like Karl Fischer titration and headspace GC. Each kilogram is packaged to prevent moisture ingress—our plant teams learned early on that careless handling at this step creates headaches for everyone downstream.

    Understanding Real-World Usage

    Laboratories in national pesticide registration programs, academic toxicologists, and legacy crop protection researchers often reach out for Endrin Ketone since there aren’t many alternatives for comparative degradation studies. The compound shows up as a metabolite and indicator in soil, water, and sediment monitoring. Technicians rely on our exacting standards for trace-level detection and calibration—one minor contaminant will throw off the entire study, so consistency isn’t a suggestion; it’s a requirement.

    An example comes from large soil testing contracts we’ve supplied for in Southeast Asia. Weather conditions, temperature swings, and variable logistics mean shelf stability counts as much as purity. The stability profile of Endrin Ketone, under real transit and storage conditions, reflects years of optimization. Sorption to glassware or seals used to be a concern; now we specify containers based on trial outcomes, not guesses. The headaches faced by field operators can only be solved by anticipating these shortfalls at the manufacturing stage.

    How Our Production Approach Translates to Reliability

    Many products called ‘pesticide intermediates’ enter the market as side-streams from unrelated chemistries. That’s never been our strategy. Endrin Ketone production uses purpose-designed reactors with high-precision temperature and agitation, tailored to the degradation pathways unique to chlorinated cyclodienes. We learned early that skipping those precautions led to off-spec lots, so the investment pays dividends in fewer out-of-spec rejections and customer problems. Our raw materials come from vetted contributors, with every drum fingerprinted by batch—this speeds investigations if harmonization issues ever surface.

    Control at multiple checkpoints prevents dust, cross-contamination, or improper labeling. Documentation includes process logbooks, origin of precursors, test reports, and chain-of-custody records. Third parties audit us regularly—not just for ISO certifications but because accredited laboratories demand supporting quality evidence. On several occasions, we’ve supplied forensic data to researchers pinpointing deviations in global distribution chains.

    Differences that Matter in the Field

    Some manufacturers handle Endrin Ketone as an afterthought. We treat it like a premium specialty, with every kilogram reflecting decades of production learning. The difference shows up in application: analytical chemists request repeat orders by lot number. They remember our batches that do not require recalibration. Out-of-spec impurity levels, which occasionally sneak through large-batch reprocessing, have led to whole series of spiked samples being rerun elsewhere. Our batch histories reveal why stringent in-process assays save time further downstream.

    We don’t lean on filler terminology—our team drills down into what clients actually observe at the bench. Some imported Endrin Ketone has come saturated with hard-to-detect isomeric contaminants. These look similar but skew results just enough to bring confusion to labs performing regulatory compliance checks for persistent organic pollutants. Field scientists come back to us since our material avoids those inconsistencies. A few grams of well-controlled compound matter more than barrels of uncertain provenance.

    Looking Back: Origins and Process Improvements

    Early on, making Endrin Ketone involved a fair amount of trial and error with reaction conditions. We traded stories with other chemists who battled runaway polymerization or persistent emulsions. Introducing better scrubbing systems and staged addition protocols stopped thermal runaways and helped tame erratic by-product streams. Our experience in wastewater stewardship also improved; today, effluent leaving our plant meets government and downstream remediation thresholds every time, which keeps our license—as well as our conscience—intact.

    Process control software and better sensor integration became priorities after a problematic year, when we lost a whole campaign to underreported solvent loss. Since that setback, we now run mass balance cross-checks and revalidate all flow meters before every campaign, no exceptions. A lesson hard learned brings lasting change. It’s these granular decisions—holding a line on upstream quality or spending extra on corrosion-resistant alloys—that ensure our plant keeps running and our customers avoid unnecessary troubleshooting.

    Safety: Not Just a Paper Commitment

    The chemical industry’s past with Endrin-related compounds means tight controls take priority over volume. Staff rotation limits exposure risk and prevents complacency. Rather than hiring cheap and fast, our teams undergo regular protocol refreshers. Safety comes from a combination of discipline, careful design, and regular inspection. We treat waste streams as products needing management, not an afterthought tacked onto the end of a campaign. Every valve, vent line, and collection tank is logged and maintained.

    Over the years, audits from both regulators and contract partners pushed us to close any procedural gaps. We’ve responded with doubled PPE checks, better containment, and more frequent third-party hazard drills. No one forgets the stories from the era of loose controls; our site’s culture passes those lessons on to every new technician. If an inspector drops by, process documentation and environmental logs reflect ongoing diligence, not a cleanup before the visit. These routines translate into safer product deliveries out the gate.

    The Larger Context: Regulation and Industry Change

    Endrin Ketone isn’t a mass-market item. National governments and international organizations monitor it closely due to environmental persistence and toxicity links. Policies evolve—sometimes abruptly—in ways that confound end-users. Having navigated registration cycles and reached mutual recognition with public laboratories, we’ve taken it on ourselves to stay abreast of every new rule or compliance bulletin.

    Each order includes origin and traceability documents matching what customs and environmental inspectors expect. By keeping risk mitigation top of mind, we provide not only the product but the confidence to users that their material won’t fall short under tight review. Years ago, failing to align with new shipment restrictions meant delays and costly product recalls. This experience pushed us to establish regulatory liaisons and legal teams who monitor international shipment requirements daily.

    Perspective on Alternatives and Emerging Needs

    The industry sometimes pitches supposed replacements for Endrin Ketone in field and laboratory testing. Our outlook is cautious—most alternatives lack the track record for precision or present their own stewardship burdens. Customers consult us about comparative performance. Decades of experience guide our advice, not sales scripts. For research where exact legacy comparison is needed, switching intermediates introduces variables no one wants. The package insert may list a substitute, but field technicians are the first to spot drift in data reliability.

    Our production teams value transparency. If alternatives eventually match the performance and compliance profile required, we’ll say so. Until then, we keep our process unchanged and focus on supporting knowledge transfer to groups maintaining archives and conducting environmental fate studies. Building trust with the experts who request our material means admitting what is and isn’t possible.

    Continual Improvement: What We’ve Learned

    Walking through the plant, old logbooks carry margin notes—‘density slightly low, check batch temp’ or ‘trace yellowing during scale-up’—that hint at the countless tweaks applied. Those notations, handed down across staff generations, reflect a commitment to detail. Procedures that work in 10-liter glassware do not always translate to 10,000-liter reactors. Our operators, technicians, and engineers have built a knowledge base as solid as any formal training.

    We’ve invested in digital monitoring for every step, but it’s the people—experienced eyes on the vessel windows or ears trained to recognize pump irregularities—who catch anomalies screens miss. Fine-tuning filtration protocols, switching filter mediums, adjusting nitrogen blanketing rates, and running on-site microchromatography: these aren’t abstract pursuits. The team experiments, shares feedback with R&D, and updates central operating instructions. Every lesson finds practical application on the next campaign.

    Environmental Responsibility: Beyond Compliance

    Manufacturing chlorinated organics brings long-term stewardship obligations. Our effluent remains below discharge limits, checked by third-party labs, with data shared transparently. We run closed-loop solvent recovery and have steadily reduced liquid and solid waste over the last decade. Scrutinizing supplier sources, we keep hazardous feedstocks under tight usage quotas.

    Field operators in environmental monitoring and safety assessment groups appreciate knowing what goes into our batches, which isn’t always the case when material appears from less selective channels. Every transfer is tracked—no shortcutting. Our group considers product stewardship an ongoing relationship rather than a checkbox requirement.

    Supporting the Next Generation of Experts

    Requests for Endrin Ketone often come from early-career researchers tasked with legacy analyses for environmental baselines. Detailed spectral data, product certificates, and impurity profiles make their lives easier. Veteran researchers reach out for specific lot numbers to replicate results from decades back. Our engagement with the academic and regulatory community informs tweaks and batch-scale improvements as practice, not just policy.

    Technical liaisons cycle through customer queries—dissolution, recovery, spiked sample prep, long-term storage tips. Each exchange provides the feedback loop that continuously upgrades both standard practice and product. We attend symposia, listen to updates from pesticide toxicology experts, and study reports on global residue trends. Our feedback mechanisms go far beyond order fulfillment.

    Handling Tough Questions and Ongoing Challenges

    Increasingly, end-users challenge us on sustainability and the true costs of maintaining stock for substances with regulatory baggage. Our response isn’t rhetoric. We’ve decommissioned older, less sustainable lines, standardized best-available control technology, and hold honest conversations about the role of chlorinated intermediates in modern chemistry. For some, Endrin Ketone represents a necessary tool with no real substitute for specific applications. For others, it is a legacy chemical under review.

    Open communication helps bridge these perspectives. Having supported researchers and technical managers across continents, our responsibility grows beyond reliable supply. It includes clear product histories, honest stewardship, and participation in industry roundtables on safe phase-outs where feasible.

    What Consistent Quality Means

    No test run, calibration, or synthetic step works without a stable foundation. Endrin Ketone, manufactured with rigor and traceability, sets the baseline for a wide swath of regulatory and research activities. Over years, our commitment has proven itself in the lab, on field expeditions, and in policy discussions. Every drum, every sample, carries a history of attention to detail—multiple steps, checks, and improvements layered across batches.

    Choosing a supply partner in today’s market comes with risks. Transparency, regulatory alignment, and real technical expertise outweigh discounted sources or unvetted intermediaries. We keep our doors open to inspectors, customers, and technical partners for a reason. That openness ensures trust, accountability, and the continuity researchers and regulators need.

    Moving Forward with Endrin Ketone

    As regulations change and industry priorities evolve, suppliers like us must adapt without cutting corners. Advances in tox monitoring, new environmental screening techniques, and legacy remediation efforts depend on sound starting materials. Endrin Ketone remains relevant because, for key applications, it outperforms lookalikes in accuracy and reliability.

    We continue to invest in people and systems that make small differences count. Whether refining particle suspension, packaging for challenging terrain, or preparing documentation for international review, we know what stands behind each order. A track record of consistency, transparency, and genuine technical support keeps critical projects on course. Among the many tasks our team tackles, keeping Endrin Ketone trustworthy always sits at the top of the list.