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Endrin Ketone

    • Product Name Endrin Ketone
    • Alias Ketone, Endrin
    • Einecs 205-049-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    205468

    Chemical Name Endrin Ketone
    CAS Number 53494-70-5
    Molecular Formula C12H8Cl6O
    Molecular Weight 386.92 g/mol
    Appearance White crystalline solid
    Melting Point 245-246°C
    Boiling Point Decomposes before boiling
    Solubility in Water Insoluble
    Density 1.75 g/cm³
    Synonyms 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalen-3-one
    UN Number 2761
    Storage Conditions Keep in tightly closed container, store in a cool, dry, well-ventilated area
    Stability Stable under recommended storage conditions
    Uses Metabolite of endrin, research chemical

    As an accredited Endrin Ketone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Endrin Ketone is packaged in a sealed 500g amber glass bottle with a secure screw cap, labeled with hazard warnings.
    Shipping Endrin Ketone should be shipped in tightly sealed containers, clearly labeled, and protected from physical damage. It must be kept away from incompatible substances and stored in a cool, dry, well-ventilated area during transport. Comply with all applicable local and international regulations for hazardous chemicals during shipping.
    Storage Endrin Ketone should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Keep it away from direct sunlight, heat, and sources of ignition. Storage should be within a secure chemical storage cabinet labeled for toxic and hazardous substances, and access should be restricted to trained personnel only.
    Application of Endrin Ketone

    Applications of Endrin Ketone in Industrial Manufacturing

    As a specialized manufacturer of Endrin Ketone, we supply downstream enterprises with consistent, high-purity material tailored for responsible and compliant use in strictly regulated sectors. Below, we outline the primary industrial scenarios where Endrin Ketone is deployed in practice, highlighting integration methods, relevant legal frameworks, and finished product pathways in each field.

    1. Advanced Agrochemical Intermediate Synthesis

    Endrin Ketone serves as a key intermediate in the synthesis of legacy organochlorine agrochemicals, specifically where regulations permit controlled manufacture for research or pest management in highly regulated markets. Downstream synthesis operations rely on precise introduction of Endrin Ketone at the cyclodiene framework modification stage to achieve the required molecular activity profile in multi-step chlorinated insecticide production.

    Industry compliance standards

    • Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade
    • Stockholm Convention on Persistent Organic Pollutants (for manufacturing exceptions and research)
    • EU Regulation (EC) No 1107/2009 – Plant Protection Products (for reference substances in laboratories)
    • OECD Guidelines for the Testing of Chemicals

    Typical usage ratio

    • Introduced at 3–7% w/w of total reactant mass at the key cyclodiene formation phase; adjusted based on desired molar conversion and yield requirements of end-use chemistry.

    Downstream process integration

    • Direct addition into closed-system reactors following the initial chlorination step; monitored to ensure minimal losses and strict containment in line with toxic substance handling SOPs.

    Final product types

    • Reference standard compounds for pesticide residue laboratories
    • Technical material for registered insecticide actives (in limited-exemption markets)

    2. Analytical Reference Material Production

    Research and regulatory laboratories use Endrin Ketone as a traceable reference standard in multi-residue analytical methods, especially for the calibration of GC-MS and GC-ECD systems required in pesticide residue analysis. Consistent physical-chemical properties and certified purity underpin its role in validating analytical performance, instrument maintenance, and method audits according to internationally harmonized protocols.

    Industry compliance standards

    • ISO 17034:2016 – General requirements for the competence of reference material producers
    • ISO/IEC 17025:2017 – General requirements for the competence of testing and calibration laboratories
    • US EPA Method 8081B – Organochlorine Pesticides by Gas Chromatography
    • AOAC Official Methods of Analysis – Multi-Residual Pesticide Testing

    Typical usage ratio

    • Diluted to 1–10 mg/L for stock solutions; final calibration layers between 0.01–1 µg/mL in analytical workflow depending on instrument sensitivity and matrix complexity.

    Downstream process integration

    • Weighing under controlled environment, then dissolved in certified solvent matrix; aliquots distributed for calibration curve preparation under validated laboratory conditions.

    Final product types

    • Certified reference materials (CRMs) in ampule packaging
    • Secondary analytical standards supplied to contract testing labs

    3. Environmental Monitoring Quality Control

    Governmental and independent monitoring programs incorporate Endrin Ketone as a quality control spike and surrogate recovery standard in the monitoring of persistent organic pollutants (POPs) in environmental samples. Its inclusion enables laboratories to quantify matrix recoveries and validate methodology integrity during air, water, and soil testing campaigns aligned with global treaties on pollutant control.

    Industry compliance standards

    • US EPA SW-846 Test Method 8270D – Semi-Volatile Organic Compounds by GC/MS
    • EN 12393 – Foodstuffs: Multi-residue methods for organochlorine pesticide residues
    • UNEP Global Monitoring Plan for Persistent Organic Pollutants
    • OECD GLP Principles (Good Laboratory Practice)

    Typical usage ratio

    • Added at 50–200 ng concentrations per extraction batch, selected to match the quantitation limits and matrix background of environmental sample types.

    Downstream process integration

    • Introduce prior to automated extraction or solid-phase cleanup; post-extraction quantification informs method performance reviews and audit compliance.

    Final product types

    • Environmental monitoring report packages
    • QA/QC certified sample test batches for national regulatory authorities

    4. Forensic and Toxicology Proficiency Testing

    Proficiency testing providers employ Endrin Ketone in blind sample sets to evaluate the capability of forensic and environmental toxicology laboratories in detection and accurate quantification of controlled legacy pesticides. This use supports objective lab performance appraisal and accreditation by providing challenging analytes in controlled scenarios.

    Industry compliance standards

    • ISO/IEC 17043:2010 – Conformity assessment: Proficiency testing
    • ANAB/ILAC Requirements for Laboratory Accreditation
    • National Institute of Standards and Technology (NIST) PT Program Protocols
    • US EPA Laboratory Quality Assurance Manual

    Typical usage ratio

    • Blended at 10–50 ppb in proficiency test matrices; concentrations validated to challenge sensitivity and identification accuracy of participant labs.

    Downstream process integration

    • Metered addition to test materials; followed by homogenization, aliquoting, and secure coding as part of controlled distribution protocols.

    Final product types

    • Proficiency testing kits for toxicological screening
    • Forensic laboratory external quality assessment samples
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    Certification & Compliance
    More Introduction

    Endrin Ketone: A Closer Look from the Factory Floor

    What Sets Endrin Ketone Apart

    At our production facility, Endrin Ketone has been a mainstay for years, trusted by agricultural chemical formulators who require consistency and precision. Recognizing the shifts in international regulatory landscapes and tighter scrutiny around organochlorine compounds, we take extra care in how we craft and control the quality of every batch. Unlike general-purpose solvents or broad-spectrum intermediates, Endrin Ketone belongs to a very focused class of chemicals. Its formula—C12H8Cl6O—features a distinctive structure that gives it particular utility in synthesis and pest control research.

    Our personnel have extensive experience refining the process parameters to achieve narrow specification ranges. We keep the purity at or above 98% by GC, targeting impurities below 1%. Moisture control remains a critical step. Small increases can lead to unwanted by-products, so we continuously invest in analytics like Karl Fischer titration and headspace GC. Each kilogram is packaged to prevent moisture ingress—our plant teams learned early on that careless handling at this step creates headaches for everyone downstream.

    Understanding Real-World Usage

    Laboratories in national pesticide registration programs, academic toxicologists, and legacy crop protection researchers often reach out for Endrin Ketone since there aren’t many alternatives for comparative degradation studies. The compound shows up as a metabolite and indicator in soil, water, and sediment monitoring. Technicians rely on our exacting standards for trace-level detection and calibration—one minor contaminant will throw off the entire study, so consistency isn’t a suggestion; it’s a requirement.

    An example comes from large soil testing contracts we’ve supplied for in Southeast Asia. Weather conditions, temperature swings, and variable logistics mean shelf stability counts as much as purity. The stability profile of Endrin Ketone, under real transit and storage conditions, reflects years of optimization. Sorption to glassware or seals used to be a concern; now we specify containers based on trial outcomes, not guesses. The headaches faced by field operators can only be solved by anticipating these shortfalls at the manufacturing stage.

    How Our Production Approach Translates to Reliability

    Many products called ‘pesticide intermediates’ enter the market as side-streams from unrelated chemistries. That’s never been our strategy. Endrin Ketone production uses purpose-designed reactors with high-precision temperature and agitation, tailored to the degradation pathways unique to chlorinated cyclodienes. We learned early that skipping those precautions led to off-spec lots, so the investment pays dividends in fewer out-of-spec rejections and customer problems. Our raw materials come from vetted contributors, with every drum fingerprinted by batch—this speeds investigations if harmonization issues ever surface.

    Control at multiple checkpoints prevents dust, cross-contamination, or improper labeling. Documentation includes process logbooks, origin of precursors, test reports, and chain-of-custody records. Third parties audit us regularly—not just for ISO certifications but because accredited laboratories demand supporting quality evidence. On several occasions, we’ve supplied forensic data to researchers pinpointing deviations in global distribution chains.

    Differences that Matter in the Field

    Some manufacturers handle Endrin Ketone as an afterthought. We treat it like a premium specialty, with every kilogram reflecting decades of production learning. The difference shows up in application: analytical chemists request repeat orders by lot number. They remember our batches that do not require recalibration. Out-of-spec impurity levels, which occasionally sneak through large-batch reprocessing, have led to whole series of spiked samples being rerun elsewhere. Our batch histories reveal why stringent in-process assays save time further downstream.

    We don’t lean on filler terminology—our team drills down into what clients actually observe at the bench. Some imported Endrin Ketone has come saturated with hard-to-detect isomeric contaminants. These look similar but skew results just enough to bring confusion to labs performing regulatory compliance checks for persistent organic pollutants. Field scientists come back to us since our material avoids those inconsistencies. A few grams of well-controlled compound matter more than barrels of uncertain provenance.

    Looking Back: Origins and Process Improvements

    Early on, making Endrin Ketone involved a fair amount of trial and error with reaction conditions. We traded stories with other chemists who battled runaway polymerization or persistent emulsions. Introducing better scrubbing systems and staged addition protocols stopped thermal runaways and helped tame erratic by-product streams. Our experience in wastewater stewardship also improved; today, effluent leaving our plant meets government and downstream remediation thresholds every time, which keeps our license—as well as our conscience—intact.

    Process control software and better sensor integration became priorities after a problematic year, when we lost a whole campaign to underreported solvent loss. Since that setback, we now run mass balance cross-checks and revalidate all flow meters before every campaign, no exceptions. A lesson hard learned brings lasting change. It’s these granular decisions—holding a line on upstream quality or spending extra on corrosion-resistant alloys—that ensure our plant keeps running and our customers avoid unnecessary troubleshooting.

    Safety: Not Just a Paper Commitment

    The chemical industry’s past with Endrin-related compounds means tight controls take priority over volume. Staff rotation limits exposure risk and prevents complacency. Rather than hiring cheap and fast, our teams undergo regular protocol refreshers. Safety comes from a combination of discipline, careful design, and regular inspection. We treat waste streams as products needing management, not an afterthought tacked onto the end of a campaign. Every valve, vent line, and collection tank is logged and maintained.

    Over the years, audits from both regulators and contract partners pushed us to close any procedural gaps. We’ve responded with doubled PPE checks, better containment, and more frequent third-party hazard drills. No one forgets the stories from the era of loose controls; our site’s culture passes those lessons on to every new technician. If an inspector drops by, process documentation and environmental logs reflect ongoing diligence, not a cleanup before the visit. These routines translate into safer product deliveries out the gate.

    The Larger Context: Regulation and Industry Change

    Endrin Ketone isn’t a mass-market item. National governments and international organizations monitor it closely due to environmental persistence and toxicity links. Policies evolve—sometimes abruptly—in ways that confound end-users. Having navigated registration cycles and reached mutual recognition with public laboratories, we’ve taken it on ourselves to stay abreast of every new rule or compliance bulletin.

    Each order includes origin and traceability documents matching what customs and environmental inspectors expect. By keeping risk mitigation top of mind, we provide not only the product but the confidence to users that their material won’t fall short under tight review. Years ago, failing to align with new shipment restrictions meant delays and costly product recalls. This experience pushed us to establish regulatory liaisons and legal teams who monitor international shipment requirements daily.

    Perspective on Alternatives and Emerging Needs

    The industry sometimes pitches supposed replacements for Endrin Ketone in field and laboratory testing. Our outlook is cautious—most alternatives lack the track record for precision or present their own stewardship burdens. Customers consult us about comparative performance. Decades of experience guide our advice, not sales scripts. For research where exact legacy comparison is needed, switching intermediates introduces variables no one wants. The package insert may list a substitute, but field technicians are the first to spot drift in data reliability.

    Our production teams value transparency. If alternatives eventually match the performance and compliance profile required, we’ll say so. Until then, we keep our process unchanged and focus on supporting knowledge transfer to groups maintaining archives and conducting environmental fate studies. Building trust with the experts who request our material means admitting what is and isn’t possible.

    Continual Improvement: What We’ve Learned

    Walking through the plant, old logbooks carry margin notes—‘density slightly low, check batch temp’ or ‘trace yellowing during scale-up’—that hint at the countless tweaks applied. Those notations, handed down across staff generations, reflect a commitment to detail. Procedures that work in 10-liter glassware do not always translate to 10,000-liter reactors. Our operators, technicians, and engineers have built a knowledge base as solid as any formal training.

    We’ve invested in digital monitoring for every step, but it’s the people—experienced eyes on the vessel windows or ears trained to recognize pump irregularities—who catch anomalies screens miss. Fine-tuning filtration protocols, switching filter mediums, adjusting nitrogen blanketing rates, and running on-site microchromatography: these aren’t abstract pursuits. The team experiments, shares feedback with R&D, and updates central operating instructions. Every lesson finds practical application on the next campaign.

    Environmental Responsibility: Beyond Compliance

    Manufacturing chlorinated organics brings long-term stewardship obligations. Our effluent remains below discharge limits, checked by third-party labs, with data shared transparently. We run closed-loop solvent recovery and have steadily reduced liquid and solid waste over the last decade. Scrutinizing supplier sources, we keep hazardous feedstocks under tight usage quotas.

    Field operators in environmental monitoring and safety assessment groups appreciate knowing what goes into our batches, which isn’t always the case when material appears from less selective channels. Every transfer is tracked—no shortcutting. Our group considers product stewardship an ongoing relationship rather than a checkbox requirement.

    Supporting the Next Generation of Experts

    Requests for Endrin Ketone often come from early-career researchers tasked with legacy analyses for environmental baselines. Detailed spectral data, product certificates, and impurity profiles make their lives easier. Veteran researchers reach out for specific lot numbers to replicate results from decades back. Our engagement with the academic and regulatory community informs tweaks and batch-scale improvements as practice, not just policy.

    Technical liaisons cycle through customer queries—dissolution, recovery, spiked sample prep, long-term storage tips. Each exchange provides the feedback loop that continuously upgrades both standard practice and product. We attend symposia, listen to updates from pesticide toxicology experts, and study reports on global residue trends. Our feedback mechanisms go far beyond order fulfillment.

    Handling Tough Questions and Ongoing Challenges

    Increasingly, end-users challenge us on sustainability and the true costs of maintaining stock for substances with regulatory baggage. Our response isn’t rhetoric. We’ve decommissioned older, less sustainable lines, standardized best-available control technology, and hold honest conversations about the role of chlorinated intermediates in modern chemistry. For some, Endrin Ketone represents a necessary tool with no real substitute for specific applications. For others, it is a legacy chemical under review.

    Open communication helps bridge these perspectives. Having supported researchers and technical managers across continents, our responsibility grows beyond reliable supply. It includes clear product histories, honest stewardship, and participation in industry roundtables on safe phase-outs where feasible.

    What Consistent Quality Means

    No test run, calibration, or synthetic step works without a stable foundation. Endrin Ketone, manufactured with rigor and traceability, sets the baseline for a wide swath of regulatory and research activities. Over years, our commitment has proven itself in the lab, on field expeditions, and in policy discussions. Every drum, every sample, carries a history of attention to detail—multiple steps, checks, and improvements layered across batches.

    Choosing a supply partner in today’s market comes with risks. Transparency, regulatory alignment, and real technical expertise outweigh discounted sources or unvetted intermediaries. We keep our doors open to inspectors, customers, and technical partners for a reason. That openness ensures trust, accountability, and the continuity researchers and regulators need.

    Moving Forward with Endrin Ketone

    As regulations change and industry priorities evolve, suppliers like us must adapt without cutting corners. Advances in tox monitoring, new environmental screening techniques, and legacy remediation efforts depend on sound starting materials. Endrin Ketone remains relevant because, for key applications, it outperforms lookalikes in accuracy and reliability.

    We continue to invest in people and systems that make small differences count. Whether refining particle suspension, packaging for challenging terrain, or preparing documentation for international review, we know what stands behind each order. A track record of consistency, transparency, and genuine technical support keeps critical projects on course. Among the many tasks our team tackles, keeping Endrin Ketone trustworthy always sits at the top of the list.