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Dibutyl Ether

    • Product Name Dibutyl Ether
    • Alias Butyl ether
    • Einecs 203-956-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    345950

    Chemicalname Dibutyl Ether
    Molecularformula C8H18O
    Molarmass 130.23 g/mol
    Casnumber 142-96-1
    Appearance Colorless liquid
    Odor Ether-like odor
    Boilingpoint 141°C
    Meltingpoint -98°C
    Density 0.769 g/cm3 at 20°C
    Solubilityinwater Insoluble
    Flashpoint 32°C (closed cup)
    Vaporpressure 12 mmHg at 20°C

    As an accredited Dibutyl Ether factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Dibutyl Ether is packaged in a 500 mL amber glass bottle with a screw cap, clearly labeled with hazard warnings.
    Shipping Dibutyl Ether is shipped as a flammable liquid, typically in tightly sealed, appropriately labeled metal drums or chemical-resistant containers. It must be stored and transported away from heat sources and oxidizing agents, in compliance with hazardous material regulations. Proper ventilation, grounding, and spill containment measures are required to ensure safe handling during shipping.
    Storage Dibutyl ether should be stored in a cool, dry, and well-ventilated area away from heat, sparks, open flame, and sources of ignition. Use tightly sealed, chemically resistant containers, and keep away from oxidizing agents and acids. Regularly check containers for leaks. Store under nitrogen or another inert atmosphere to minimize peroxide formation. Properly label and ground all storage vessels.
    Application of Dibutyl Ether

    Applications of Dibutyl Ether in Industrial Manufacturing

    Dibutyl Ether serves as a reliable specialty solvent and process aid across several advanced chemical manufacturing sectors, contributing to high-value industrial processes. As a dedicated manufacturer, we supply uncompromising purity and batch consistency to support stringent downstream applications where Dibutyl Ether provides its irreplaceable performance advantages. Below, we detail its specific use cases with relevant compliance standards, formulation guidance, process steps, and finished product types.

    1. Lithium Metal Battery Electrolyte Production

    Battery cell manufacturers rely on high-purity Dibutyl Ether as a co-solvent in non-aqueous electrolyte formulations due to its beneficial volatility profile and compatibility with lithium salts. It improves the wetting and infiltration of porous separator membranes, enhancing the performance and safety of secondary lithium metal and lithium-sulfur cells used in electric vehicles and energy storage. Downstream cell assembly environments require solvents to meet both equipment compatibility and environmental control standards.

    Industry compliance standards

    • IEC 62660-2 requirements for lithium secondary cells
    • UN 38.3 transport safety test for lithium batteries
    • REACH Annex XVII solvent purity controls
    • ISO 9001:2015 and ISO/TS 16949 for automotive supplier quality

    Typical usage ratio

    • 5%–15% by volume in mixed carbonate/ether electrolyte solutions; formulation adjusted based on cell design and targeted conductivity-wetting balance

    Downstream process integration

    • Solvent charging step in closed-loop electrolyte mixing systems prior to moisture-sensitive electrolyte filling in battery cell lines

    Final product types

    • Lithium metal pouch cells for automotive OEMs
    • Lithium-sulfur large format batteries for grid storage
    • Specialized power cell modules for robotics and aviation

    2. Grignard Reagent Synthesis for Pharmaceutical Intermediates

    Organic synthesis operations leverage Dibutyl Ether in Grignard reagent manufacturing, where its low reactivity, high boiling point, and ability to stabilize organomagnesium complexes are critical. This solvent ensures precise control of exotherms and optimal reaction kinetics during the preparation of halogenated intermediates widely used in the pharmaceutical actives sector. The entire process strictly adheres to validated cGMP protocol and pharmacopeia standards for raw material handling and residue limits.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP–NF <467> Residual Solvents guidance
    • European Pharmacopoeia (Ph. Eur.) 2.4.24 solvent limits
    • FDA 21 CFR Part 211 Finished Pharmaceuticals GMP

    Typical usage ratio

    • Used as the primary anhydrous solvent: 85%–100% by volume in reaction vessel; residual trace amounts managed via validated drying and stripping steps

    Downstream process integration

    • Initial addition and charge solvent in Grignard reagent reactors, followed by in situ quenching to produce halide intermediates for onward active pharmaceutical ingredient (API) synthesis

    Final product types

    • Brominated and iodinated pharmaceutical intermediates
    • Key organomagnesium compounds for API building blocks
    • API-grade fine chemicals destined for regulated drug substance plants

    3. Catalyst Extraction in Polymer Manufacturing

    In advanced polyolefin and specialty polymer production, plant engineers use Dibutyl Ether for selective extraction of catalysts and residual organometallics from polymerization reactors. Its high solubility with common Ziegler–Natta and metallocene catalysts supports improved catalyst recovery and disposal, contributing to tighter control of residual metals and polymer purity. The process must document removal efficiency to meet industry and safety standards for polymer grade consistency and final product compliance.

    Industry compliance standards

    • FDA 21 CFR 177.1520 for polyolefin contact polymers
    • ISO 22000:2018 for food-contact packaging compliance (for downstream users)
    • ASTM D6248-98 for catalyst residue analysis in polymers
    • EU 10/2011 food-contact plastics regulation (for downstream packaging films)

    Typical usage ratio

    • 10%–25% by volume in extraction wash stages; concentration tuned to catalyst loading and throughput—higher usage for heavily loaded reactors or high contaminant removal specifications

    Downstream process integration

    • Post-polymerization treatment in batch or continuous extraction columns before devolatilization and pelletizing stages

    Final product types

    • Polypropylene pellets for injection molding
    • Low-residue polyethylene films for food packaging
    • Technical-grade thermoplastics for automotive and medical applications

    4. Solvent Dehydration in Laboratory and Industrial Scale Applications

    Specialty and contract manufacturers employ Dibutyl Ether for solvent dehydration and azeotropic distillation, removing trace moisture from sensitive organic solvents and intermediates. Owing to its azeotrope-forming ability, it supports robust water removal in both pilot plant and production-scale environments, thus protecting downstream process yields and preventing side-reactions in moisture-sensitive synthesis steps. These critical procedures help manufacturers preserve batch quality, with full traceability and quality documentation.

    Industry compliance standards

    • ISO 17025 requirements for analytical and drying process validation
    • Pharmacopeial monographs on acceptable residual moisture for solvents (USP 921/Ph. Eur. 2.5.12)
    • GMP Annex 1 for API manufacturing atmospheric control
    • Responsible Care protocols for solvent handling

    Typical usage ratio

    • 5%–18% by volume added to solvent charge during azeotropic distillation, typically determined based on initial moisture content and desired dryness endpoint (KF ≤ 0.05% w/w)

    Downstream process integration

    • Charged to distillation train as part of pre-reaction solvent conditioning steps, removed after water extraction phase before introduction to sensitive organometallic or condensation reactions

    Final product types

    • Ultra-dry organic solvents for specialty synthesis
    • High-purity intermediates for pharmaceutical and agrochemical processes
    • Precision laboratory reagents for analytical QC or R&D use

    5. Extraction Solvent in Natural Flavor and Fragrance Manufacture

    Dibutyl Ether has established value in natural product extraction—specifically for isolating essential oils, resins, and aroma compounds in the flavors and fragrance sector. Process engineers select this solvent due to its low miscibility with water and stability at elevated temperatures, enabling superior extraction efficiency and product recovery. Safe handling and regulatory due diligence are crucial, as manufacturers must meet food additive and IFRA safety assessments in addition to solvent residue specifications.

    Industry compliance standards

    • EU Regulation (EC) No 1334/2008 on flavorings and food ingredients
    • IFRA Guidelines for fragrance ingredient processing
    • ISO 9235 for natural aromatics
    • JECFA/FEMA GRAS status for solvent use (limited per chemical and application)

    Typical usage ratio

    • 12%–22% by volume relative to biomass charge in multi-step extraction; percentage adjusted for target aroma panel, resin solubility, and desired purity of concentrate

    Downstream process integration

    • Used as primary or secondary extraction solvent during batch or continuous solid-liquid extraction, followed by separation and distillation under reduced pressure for solvent recovery

    Final product types

    • Natural essential oil isolates for commercial perfumery
    • Concentrated natural flavorings for food and beverage
    • Oleoresin extracts for specialty aroma compounding
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    Competitive Dibutyl Ether prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Dibutyl Ether: Direct from the Chemical Manufacturer

    Rooted in Production, Shaped by Experience

    Every batch of Dibutyl Ether leaving our facility tells a story of deliberate process, rigorous oversight, and a firm belief that quality results from hands-on know-how. As a company deeply involved in the daily rhythm of synthesis, distillation, and product testing, we don’t just fill drums and ship orders. We take part in defining the character and consistency of Dibutyl Ether, from the first mixing vessel to the last seal on the container.

    The market classifies Dibutyl Ether under CAS Number 142-96-1. Chemists recognize it by its chemical formula C8H18O. We see it every day as a clear, mobile liquid with a distinctive, slightly sweet ether odor, one that speaks to our technicians as soon as they open the sampling port. It offers a lower density than water and is immiscible with it by nature. These features don’t just define its identity; they determine where it thrives as a process chemical.

    Most requests arrive referencing standard purity grades, typically 99% minimum, where water and peroxides stand as the main contaminants to eliminate. Our ongoing improvements focus on those details. Regular investment in solvent-drying stations, inert gas blanketing, and closed-loop distillation pays off in lower moisture levels and controlled peroxide formation, validated by in-house GC and Karl Fischer analysis. That’s the difference experience makes: every process parameter remains open to scrutiny, every batch receives custom attention, and our plant personnel bring in years of procedural continuity.

    Why Dibutyl Ether Matters

    Dibutyl Ether lives at the intersection of classic and advanced chemistry. As an organic solvent, it sits in a narrow band between more volatile diethyl ether and structurally heavier ethers like tetrahydrofuran or higher molecular weight glymes. In everyday manufacturing, this positions it well for lithium battery electrolyte processing, Grignard reaction media, extraction operations, and as a specialty solvent in certain pharmaceutical syntheses. Its low water solubility and moderate boiling point (around 142°C) grant it a balance between volatility and solvent strength.

    Clients in the lithium battery field depend on Dibutyl Ether’s ability to dissolve lithium salts while resisting moisture pick-up during cell assembly. We track the drift of battery technology closely, noting shifts in electrolyte composition. Our Dibutyl Ether delivers reliable moisture and impurity control, minimizing risks of hydrolysis and unwanted side reactions. For customers running Grignard or other organometallic systems, they ask—again and again—for the reassurance that only experience in stripping off trace metals and scavenging trace acidity brings. These are no longer theoretical refinements. They form the backbone of predictable reaction outcomes.

    In pharmaceutical synthesis, the solvent often fades behind headlines about active ingredients, but we know from years around reactors and centrifuges—an unpredictable side reaction or an incomplete work-up can trace directly to a contaminated or unstable solvent. Dibutyl Ether’s chemical stability, moderate solvency for non-polar and weakly polar organics, and low tendency for peroxide formation if handled right, have made it a strong player in processes that cannot absorb costly interruptions.

    Specifications and Their Place in Practical Use

    On paper, Dibutyl Ether typically ships with a purity specification of 99% minimum, water below 0.1%, and peroxides under 0.005%. Those aren’t just printed numbers to us—but targets verified against each drum and tank, with batch numbers recorded and full traceability in place. Our records show that even when customers call for “standard product,” the definition of standard can vary. Electronics, specialty polymers, and advanced surfactant synthesis often tighten those specs, calling for sub-ppm water and stringent ionic cleanness—requirements our team addresses with pre-activation, molecular sieving, and ultra-clean filling lines.

    Drums and Intermediate Bulk Containers each undergo pressure purging and nitrogen blanketing, not out of habit, but because we’ve walked customers’ job sites and seen the downstream effects of atmospheric exposure. The goal: deliver Dibutyl Ether that acts as a pure, predictable tool, not a variable that requires rework.

    Comparisons with Other Ethers

    Users choosing between Dibutyl Ether and its close relatives often cite volatility, toxicity, and solvation profile. In many cases, diethyl ether lures with low boiling and classic utility in extraction, but its flammability and tendency for peroxide buildup send some users searching for a safer alternative. Tetrahydrofuran offers more polar solvency, making it commercially valuable in polymer synthesis, though with its own unique hazards—autoxidation, higher cost, and more regulatory hurdles.

    Dibutyl Ether stakes out middle ground. It brings a much lower vapor pressure than diethyl ether (translating to safer handling and fewer emissions), plus a higher flash point, easing transportation constraints. The odor, though distinct, is manageable in well-ventilated industrial spaces. Its somewhat heavier molecule produces less aggressive solvency than tetrahydrofuran. For reactions needing a relatively inert, hydrophobic environment—chromatographic separations, certain hydride reductions, or alkylations—Dibutyl Ether often fits where other ethers either evaporate too quickly or interact too much with the starting materials.

    Pricing and sourcing remain industry realities—many downstream customers perform annual reviews, comparing budget, transport safety, workplace controls, and environmental exposure. Dibutyl Ether frequently earns its place because facilities with good handling systems report fewer incidents of solvent loss or degraded product. Its moderate boiling point suits simple recovery through distillation; spent solvent streams require less elaborate treatment than more persistent, higher boiling ethers. We notice fewer customer complaints about downstream impurity buildup, and plant operators see quicker turnaround when using Dibutyl Ether as a transfer or cleaning medium.

    How Manufacturing Practice Directly Impacts Product Strength

    Owning the entire manufacturing process means understanding where bottlenecks and risks appear. In handling Dibutyl Ether, we devote resources to continuous analytics. Peroxide management gets special attention. Over months and years, we’ve learned that storage under nitrogen, light exclusion, and regular batch clearing help prevent hazardous buildup. We track real-world feedback: no laboratory incident or factory delay stays buried in a report. Our plant engineers test the storage tanks for temperature fluctuations, material compatibility, and drum integrity—lessons learned from the occasional spill or leaking gasket, which doesn’t make for neat marketing copy, but does produce real risk reduction.

    Every change in raw material source or distillation column operation passes through a review by development chemists and operations managers. There’s no substitute for seeing the color shift in a sight glass, smelling a slightly off batch, or fielding a call from a trusted customer who notices a difference on their end. This hard-won feedback cycle means each lot of Dibutyl Ether evolves, gets a little better, and supports more complex applications.

    Shipping departments routinely examine container sealing, banding, and labeling. Small failures here cascade into bigger issues: spilled solvent, unscheduled maintenance, and lost time. It’s no secret in chemicals: product quality doesn’t just stem from reagent purity, but from every human hand and automated valve in the process.

    Improving Safety and Environmental Responsibility

    Safety protocols never gather dust in the real world of Dibutyl Ether manufacturing. Plant workers remind us daily that promises about safety mean little unless followed by real investment. We upgraded vented storage tanks, reinforced flameproof areas, and increased routine peroxide testing not for show, but as a response to industry events and near-misses. Local authorities visit, inspect, and often push for tighter controls—and we respond by staying ahead of regulatory changes.

    Workers rely on monitored air quality, prompt incident reporting, and access to proper fire suppression technology. Environmental releases bring hard questions to the production floor. As a hydrophobic solvent, Dibutyl Ether requires more than basic containment; spill response calls for dedicated equipment and environmental follow-up. That attention carries over to wastewater management and vapor abatement. We appreciate that widespread use of sustainable energy, best-in-class ventilation, and solvent recovery isn’t optional—it’s baked into responsible site operation.

    From an emissions standpoint, Dibutyl Ether measures relatively well against more volatile ethers. Reduced evaporative loss means less solvent makes its way into the environment. We build on this by maintaining vapor recovery units and encouraging solvent recycling programs within customers’ facilities.

    Product Applications: Details from Years on the Ground

    Ask a group of chemists where Dibutyl Ether finds its best use, and answers often center on its role as a solvent in laboratory synthesis. We’ve witnessed its journey from small-scale pilot plant to full commercial adoption, with steady expansion into new sectors.

    In lithium battery manufacture, the solvent stands out for its compatibility with common conductive salts and solid-state precursor materials. Customers building pilot lines in Asia and Europe now specify lower trace water and total halides than even five years ago, forcing us to dissect every fill, every line flush, every test protocol. The push for lighter, longer-life batteries hinges on every part per million—solvent included. Segments of electronics and semiconductor fabrication have also experimented with Dibutyl Ether as a rinse or intermediate carrier, tolerating less solvent residue and more precise purity than earlier users.

    In extractive industries, Dibutyl Ether’s balance of volatility (neither boiling off too quickly nor lingering as a residue) puts it to work in plant extraction processes, flavors and fragrances, and instances where a less reactive ether shows cost or safety benefit over more established solvents. The same moderate lipophilicity supports applications in pesticide formulation and pigment manufacturing that avoid more hazardous or regulatory-burdened options.

    Pharmaceutical projects tucked deep in workflow often call for custom solutions. Our batch records show that a surprising fraction of Dibutyl Ether leaves the plant labeled not as general product, but with custom shipment requirements—dry-ice chilled, double-sealed, or with enhanced tamper resistance. Teams developing API intermediates or scaling up new process routes count on us not just for purity, but for the working relationships needed to tweak process parameters on the fly.

    Addressing Industry Challenges and Solutions

    No chemical story runs without hurdles. The market for ethers faces upstream stressors—volatile feedstock prices, shipping constraints, and ongoing shifts in downstream demand. We see the rise of new competitors, some offering material at razor-thin margins. Our response roots in value rather than more paper-thin selling points: we offer support that runs from answering midnight calls about shipment delays to engaging directly with process engineers facing yield decline or residue issues.

    Customers ask—often bluntly—for proof that Dibutyl Ether matches their performance needs today and five years from now. Reliability rests partly on supply assurance (building redundant lines, qualifying alternate raw suppliers) and partly on honest technical support. Downtime, batch rejection, and rework are problems we share with our customers, standing in the same queue as they wait for results. Our technical staff has accompanied clients through root-cause analysis of yield loss, scaling hiccups, or material compatibility questions—gathering stories and data that flow back into our continuous improvement efforts.

    One growing challenge involves the push for reduced environmental footprint across solvents. Dibutyl Ether occupies a tricky spot: friendlier than some, but still flammable and an air-water contaminant if neglected. Part of our project work includes tracking solvent flows, offering solvent management consultation, and supporting solvent substitution evaluations. Some customers seek alternatives or process redesigns to minimize residuals; our role is to supply data, trial samples, and improvement strategies, not hold onto exclusive supply relationships at all costs.

    Traceability now matters more than ever. Digital batch tracking, documented cleaning schedules, and electronic certificates of analysis aren’t just compliance tools but essential for troubleshooting unexpected performance dips. Production staff undergo regular retraining—every time a new regulation lands or an incident somewhere in the industry prompts tighter risk review.

    Price pressure never lets up. Plant managers see invoices for energy, maintenance, procurement—and know that pennies per kilogram make or break operational budgets. By focusing on stability, predictable output, low turnaround time, and minimal transport problems, we help keep Dibutyl Ether a solvent of choice, not a line item at risk of substitution.

    Continuous Growth through Direct Manufacturing Experience

    Most office descriptions miss the pace and pressure of real chemical production. On the ground, every improvement to Dibutyl Ether process comes from practical experiment—from tuning column temperatures to trialing new filtration designs, not from theory alone. A big part of better product rests on deliberate, team-driven habit improvement: error logs, open safety culture, and willingness to admit and dig into a mistake. We’ve tracked more than a decade of incremental changes—adjusting heat input, upgrading flow meters, documenting peroxide formation under different conditions—and those cumulative lessons speak to the real-life, granular difference in each shipment that leaves the site.

    Research and development don’t live in isolation. We build new blends, alternative grades, and targeted additives in direct response to customer challenges and process bottlenecks. In recent years, battery and pharma clients demanded solvents cut to dry specifications we once thought unneeded; scale-up teams brought us feedback about reaction reproducibility and work-up ease, which now inform how we qualify every new supply lot.

    We avoid crowing about every success—real progress comes from quietly fixing problems before they filter out to customers. A line worker adjusting the reflux ratio, a QC analyst flagging slightly off color in an inbound raw material, a shipping manager double-checking load documentation—each becomes part of how Dibutyl Ether goes from raw feedstock to finished solvent, ready for critical use but always asking for one more improvement.

    The Difference Direct Manufacturing Makes

    Traders, distributors, and resellers know price points, but rarely see a batch change hands, walk the length of a filling line, or diagnose an out-of-spec scenario in real time. As a manufacturer, every liter of Dibutyl Ether carries the weight of our plant’s reputation. Customers have visited, walked our aisles, and commented on procedure, not just product. They audit our inspection records, sanitation procedures, and ask for proof of every claim—purity, safety, traceability, and sustained supply continuity.

    Decades of direct production shape our viewpoint. We watch shifts in regulatory frameworks, monitor industry health and safety advisories, and adapt. Certifications and regulatory compliance don’t result from back-office checklisting; our teams deal with them on the floor, living their implications.

    Each interaction, site experiment, and customer call forms a feedback cycle. Dibutyl Ether continues to evolve—not just as a chemical, but as a result of relentless, day-to-day efforts welded to care, skill, and the quiet pressure of getting things right for those who depend on us. Whether your needs grow with new markets or remain steady in established processes, direct-from-manufacturer solvent supply means more than a nameplate or a datasheet. It delivers the full story, not just the product.