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Di-Sec-Butylamine

    • Product Name Di-Sec-Butylamine
    • Alias DSBA
    • Einecs 202-854-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    840817

    Chemical_Name Di-sec-butylamine
    CAS_Number 13952-84-6
    Molecular_Formula C8H19N
    Molecular_Weight 129.24
    Appearance Colorless to pale yellow liquid
    Boiling_Point 126-128°C
    Density 0.766 g/mL at 25°C
    Flash_Point 24°C (closed cup)
    Solubility_in_Water Slightly soluble
    Refractive_Index 1.417-1.419 at 20°C

    As an accredited Di-Sec-Butylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Di-Sec-Butylamine is packaged in a 500 mL amber glass bottle with a secure screw cap, labeled with chemical details.
    Shipping Di-Sec-Butylamine should be shipped in tightly sealed containers, clearly labeled, and compliant with local and international regulations for hazardous chemicals. It must be kept away from heat, sparks, open flames, and incompatible materials. Ensure proper ventilation and secondary containment during transit to prevent leaks, spills, or exposure. Handle with appropriate safety precautions.
    Storage Di-Sec-Butylamine should be stored in a cool, dry, and well-ventilated area, away from heat, ignition sources, and incompatible materials such as acids, oxidizers, and halogens. Store in tightly sealed containers, clearly labeled, and protected from moisture. Ensure containers are made of compatible material to prevent chemical reaction. Access should be restricted to trained personnel using proper personal protective equipment.
    Application of Di-Sec-Butylamine

    Applications of Di-Sec-Butylamine in Industrial Manufacturing

    Di-Sec-Butylamine serves as a key intermediate in a range of chemical processes, particularly in agrochemical synthesis, pharmaceutical raw material production, corrosion inhibitor formulations, and rubber chemical manufacturing. As a direct manufacturer, we ensure that this material meets strict quality standards to support safe and efficient end-use production.

    1. Agrochemical Synthesis: Herbicide and Pesticide Intermediates

    Di-Sec-Butylamine forms a critical building block in the synthesis of selective herbicides and pesticide active ingredients, particularly phenoxyalkanoic acid derivatives such as 2,4-D and MCPA salts. Many leading agrochemical producers use it for neutralization and amination steps that require high specificity in reactivity and conversion yields. The purity of the amine has a direct impact on herbicide salt crystallinity and stability in formulated products. Quality assurance in this segment is managed through batch traceability and process audits as required by regulatory authorities.

    Industry compliance standards

    • EU Regulation (EC) No 1107/2009 on Plant Protection Products
    • US EPA guidelines for Agricultural Chemicals (CFR Title 40)
    • FAO/WHO Specification for pesticide technical materials
    • ISO 9001:2015 for agrochemical manufacturing quality management

    Typical usage ratio

    • Stoichiometric addition of 1–1.1 molar equivalents per mole of acid in salt formation
    • Ratio adjustments based on target pH and solubility parameters of the end product

    Downstream process integration

    • Adds during amination and neutralization steps in herbicide technical production
    • Used in closed-system reactors with real-time pH and temperature monitoring
    • Post-reaction crystalline purification for solid salt formation

    Final product types

    • 2,4-D (Di-Sec-Butylamine salt) water-soluble concentrates
    • MCPA (Di-Sec-Butylamine salt) EC formulations
    • Mixed amine salt herbicide blends

    2. Pharmaceutical Synthesis: Intermediate for Active Pharmaceutical Ingredients (API)

    Our material enters pharmaceutical ingredient manufacturing as a secondary amine nucleophile, facilitating amide and carbamate bond formation. Manufacturers employ it for specific condensation and alkylation stages while demanding precise impurity controls and batch reproducibility. Each lot receives comprehensive analytical support to ensure conformance with cGMP and pharmacopeial specifications, as trace amine levels significantly affect API safety profiles and regulatory submissions.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 211 (Drug CGMPs)
    • European Pharmacopoeia (monograph compliance as required per molecule)

    Typical usage ratio

    • Typically 0.95–1.2 molar equivalents per targeted carboxyl or alkyl halide group
    • Optimization based on target API yield and byproduct minimization strategies

    Downstream process integration

    • Incorporation at condensation or amination stages of API synthesis
    • Use in dry or aqueous phase depending on substrate solubility
    • Follow-up removal via distillation or extraction prior to API crystallization

    Final product types

    • Intermediates for antimalarial and cardiovascular APIs
    • Active moieties with secondary amine structural motifs
    • Final APIs for human and veterinary pharmaceuticals

    3. Corrosion Inhibitor Formulation for Industrial Cooling and Oilfield Applications

    In oil & gas and industrial water system engineering, Di-Sec-Butylamine serves as an organic corrosion inhibitor component, providing nitrogenous film-forming properties for protecting steel and ferrous alloys. Downstream blenders integrate this amine in proprietary synergist packages, carefully controlling dosage to balance inhibition effectiveness with eco-toxicity limits. Product stability relies on consistent amine quality and correctly sequenced addition in blending operations, with extensive documentation for REACH and OSHA compliance.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 pre-registration and dossier requirements
    • US OSHA Hazard Communication Standard 29 CFR 1910.1200
    • API RP 752 (for corrosion inhibitor use in oil and gas production)
    • EN ISO 12944 for surface protection of industrial equipment

    Typical usage ratio

    • 0.1–1.0% by total weight in final inhibitor blend for water systems
    • Up to 5% in oil-soluble inhibitor concentrations for pipeline applications

    Downstream process integration

    • Metered addition during aqueous or solvent blending of corrosion inhibitor packages
    • In-line dosing into recirculating water or hydrocarbon systems
    • Compatibility screening with other inhibitor and dispersant chemistries

    Final product types

    • Industrial closed-loop water treatment inhibitor packages
    • Oil & gas pipeline corrosion protection blends
    • Combination oxygen scavenger and filming amine products

    4. Rubber Chemical Synthesis: Accelerator and Vulcanization Additive

    Rubber compounding plants use Di-Sec-Butylamine for the synthesis of select accelerator intermediates and as an additive contributing to the vulcanization control of specialty elastomers. It acts in the production of sulfenamide and dithiocarbamate accelerators, where precise feeding and reaction temperature are critical for both yield and downstream physical properties of rubber goods. Quality control relies on amine purity assessment and trace metals screening, in line with industry norms for technical-grade additives.

    Industry compliance standards

    • ISO 9001:2015 for specialty chemical manufacturing in rubber industry
    • ASTM D4670 for rubber curing and vulcanization agent characterization
    • REACH compliance for production and application in rubber processing
    • Customer-adopted CSR standards for automotive and tire sectors

    Typical usage ratio

    • 0.5–2.5% based on total accelerator batch for sulfenamide synthesis
    • Adjustment subject to target accelerator type and downstream compounding formulas

    Downstream process integration

    • Direct reaction with sulfenyl chloride or carbamoyl chloride intermediates in closed reactors
    • Fed in liquid or aqueous phase according to manufacturer’s equipment
    • Further processed into powder or liquid accelerator masterbatches

    Final product types

    • Sulfenamide and dithiocarbamate rubber accelerators
    • Masterbatch rubber additives
    • Vulcanized technical rubber articles (automotive components, seals, hoses)

    5. Specialty Chemical Manufacturing: Custom Synthesis of Functional Intermediates

    Chemical plant operators request Di-Sec-Butylamine for custom-synthesized intermediates in performance coating resins, surfactant amides, and fine chemical crosslinkers. Applications typically require tight process controls and customized batch protocols, with facility-wide monitoring for VOC handling, trace contaminant minimization, and adherence to occupational health and safety procedures. Documentation covers both in-house GMP procedures and supply chain transparency for end-use sectors including electronics, adhesives, and surface coatings.

    Industry compliance standards

    • ISO 14001 Environmental Management Systems
    • US TSCA (Toxic Substances Control Act) New Chemical Notifications
    • GMP (Good Manufacturing Practices) for specialty chemicals
    • Industry-specific supplier qualification audits (e.g., IPC for electronics)

    Typical usage ratio

    • 0.1–2.0 molar equivalents, based on reaction selectivity and end-use application requirements
    • Adjusted according to product line specifications and QC sampling feedback

    Downstream process integration

    • Charged in early-stage amide or imide functionalization steps
    • Utilized under inert atmosphere or within nitrogen-purged batch reactors
    • Integrated into downstream purification via solvent extraction or membrane filtration

    Final product types

    • Epoxy resin hardeners and surface coating amines
    • Functional surfactant amides for emulsifier production
    • Crosslinking agents for specialty adhesives and electronic encapsulants
    Free Quote

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    Certification & Compliance
    More Introduction

    Introducing Di-Sec-Butylamine: Practical Insights from a Manufacturer’s Floor

    Getting to Know Di-Sec-Butylamine

    In our factory, day in and day out, we handle the production of countless essential chemicals. One that stands out in performance and reliability is Di-Sec-Butylamine, known by some chemists as 2-Butanamine, N-sec-butyl-. Quite a mouthful, but its significance is easy to grasp once you know where it’s used and how it behaves in the demanding settings of chemical manufacturing. We craft Di-Sec-Butylamine with a focus on purity and consistency because we know industrial clients expect strict standards. Product quality doesn't just happen—we measure, test, and double-check everything, batch after batch.

    What Sets Di-Sec-Butylamine Apart?

    I’ve seen plenty of alkylamines roll out from production, but Di-Sec-Butylamine brings a balance that appeals to several key industries. Its molecular structure, C8H19N, gives it properties suited for applications where a secondary amine is required. Unlike simple monoalkyl amines, Di-Sec-Butylamine offers increased steric hindrance and unique reactivity, stabilizing certain reactions and offering better control for chemists working to make intermediates for pharmaceuticals, agrochemicals, and rubber chemicals. That extra branching in its molecular structure—the two secondary butyl groups—lets it perform with a lower risk of side reactions compared to linear or primary amines.

    Why Chemists Trust This Material

    Over the years, our R&D and production teams have studied how our product holds up during complex syntheses. Chemists trust Di-Sec-Butylamine because it brings a cleaner reaction pathway and often fewer byproducts in multi-step reactions. Many colleagues share their feedback after large-scale syntheses: they experience less trouble with purification, which cuts time and waste.

    Our technical staff often speak directly with customers’ lab managers. The recurring message: Di-Sec-Butylamine stands up to repeated use, stores well under dry, cool conditions, and its characteristic amine odor allows easy detection of leaks—an important safety point. It has a boiling point high enough to remain liquid under standard processing conditions, yet it volatilizes predictably when heated, making recovery efficient in closed systems.

    Targeted Uses Across Diverse Industries

    Several industries rely on amines, but not all projects suit the same structure. We see Di-Sec-Butylamine go most frequently to three sectors. First, in pharmaceutical intermediate production, it functions as a building block for certain APIs and fine chemicals. The steric effects of its bulky groups lend selectivity when creating chiral centers—where precision makes all the difference in drug quality. In agriculture, it helps form effective herbicide products and fungicide intermediates, where the unique balance of reactivity and selectivity can mean more potent and stable active ingredients.

    Some of our clients come from specialty rubber manufacturing. Di-Sec-Butylamine acts as a vulcanization accelerator, improving processing times and final mechanical properties. It can also neutralize acidic catalyst residues that might otherwise degrade product performance. It’s not the generic solution—customers mold their formulations to leverage its structure for a tailored boost in rubber resilience and resistance.

    Model Variants and Production Consistency

    We’re known for offering a standard grade of Di-Sec-Butylamine with purity consistently above 98%. That specification is no accident. Years ago, we faced batches with too many unknowns, but upgrades to distillation and inline analytic controls solved those issues. As feedback rolled in from clients seeking even tighter tolerances, we responded by developing a high-purity variant, pushing further towards 99.5%. Our teams track solvent residues, water content, and secondary impurities by integrating modern GC and NMR QC protocols. Each drum or IBC that leaves the factory includes a certificate that reflects these tight controls, and our records reflect the actual batch data, not generic templates.

    Why Pure Inputs Matter Downstream

    Folks outside the plant sometimes underestimate what a difference even fractional impurities can make inside a bigger chemical process. Several pharmaceutical partners once faced bottlenecks caused by clogged reactors downstream, traced back to poorly refined amines from other sources. After switching to our Di-Sec-Butylamine, batch yields not only went up, but recurring cleaning cycles dropped. They reduced downtime, labor, and solvent usage. In rubber production, inconsistent amines can trigger unwanted side-reactions, yielding off-spec product that can cost a fortune in rework. We keep our lines clean to avoid contamination, and routine audits ensure our deliverables match our claims every month of the year.

    Safety, Packaging, and Shelf Life Considerations

    Packaging seems simple, but from factory experience, there is always new ground to cover. Our warehouse packs Di-Sec-Butylamine in steel drums with leak-proof liners. There’s no substitute for keeping the product under nitrogen to avoid oxidation and moisture uptake—one reason we always check seals before shipping. Over time, we noticed clients who stored the containers in humid or fluctuating temperatures saw a drop in purity. We started providing tips: keep containers sealed tightly, shaded from direct sunlight, and avoid storing near oxidizing agents or acids. While the product stores well, it should flow from the tank to usage lines without long delays, minimizing the risk of hydrolysis or absorption of atmospheric CO2.

    Differences from Other Amines: The Manufacturer’s Perspective

    The lab talk often turns to how Di-Sec-Butylamine differs from other secondary or tertiary amines. Compared to Dimethylamine or Diethylamine, Di-Sec-Butylamine presents a larger, more branched structure. This branching shifts both its physical characteristics—higher boiling point, greater hydrophobicity—and its chemical profile. The greater size means it sometimes demands more careful handling to achieve dissolution, particularly in polar solvents, but the advantages in selectivity during synthesis more than compensate. It is less volatile than simpler amines, which cuts down on workplace exposure risks. Our staff prefers working with it over some smaller, more noxious amines for this reason.

    Primary amines like n-Butylamine serve well as reactants in other processes, but when reactions call for a true secondary, Di-Sec-Butylamine’s unique structure keeps things predictable and clean. Some tertiary amines offer similar sterics, yet they lack the N-H bond crucial for hydrogen bonding or as a proton acceptor. If your synthesis needs a base that is both robust and not prone to overreacting, you will find Di-Sec-Butylamine can serve in roles too harsh or unforgiving for other amines.

    Handling and Worker Safety: Real Plant Experience

    Every operator values products that don’t create extra hazards. Our safety protocols include tailored PPE for handling amines. With Di-Sec-Butylamine, good ventilation in the storage and dispensing areas is enough to keep airborne concentrations to a minimum. During transfers, splash goggles and nitrile gloves are the standard, along with quick-drench showers in the rare case of spills. Our training sessions focus on early detection of leaks, thanks to its distinct aroma, but it does not exhibit the same rapid volatilization found with smaller amines, making time on job safer for personnel.

    Reducing Environmental Footprint—A Long-Term Goal

    Manufacturing inevitably produces waste, but our team spends considerable effort trying to minimize it. We recycle amine-containing wash waters in secondary processes, and residuals from distillation get neutralized and converted to less harmful effluents. The advantage of Di-Sec-Butylamine lies partly in its stability—many impurities or residues can be readily separated or treated prior to waste disposal. Environmental standards call for ever-lower emissions and waste loads, so by focusing on process-improvement and material purity, we’ve trimmed both direct releases and downstream impacts.

    Supporting Innovation for End Users

    Clients often approach us with new formulations and products in development that depend on consistent amine inputs. Our technical support staff regularly collaborates on pilot projects to see if Di-Sec-Butylamine can replace more hazardous or unreliable reagents. In one agricultural project, switching from a more toxic amine to our secondary butylamine let their team hit regulatory targets and ease workplace safety compliance. These discussions don’t just push volume—they teach us how minor molecular tweaks alter behavior in the real world. Such feedback loops let us refine both our manufacturing and our quality-control targets.

    Reliability Backed by Real-World Data

    We track feedback, not just sales. Every quality complaint, every positive remark, gets entered into our system so our technical team can spot patterns. More than once, long-term users identified subtle changes in reaction yields or final product color that traced back to minor changes in amine quality. Because we measure by actual lot performance, we know which production campaigns yield the best results and adjust upstream processes. This ongoing cycle of data gathering, adjustment, and customer outreach grounds our E-E-A-T credentials: we are in the business, not just moving material from one warehouse to another.

    Regulatory Focus and Traceability

    For manufacturers in Europe, the Americas, and Asia, batch traceability means more than paperwork. Our production logs connect raw material lots, process settings, and analytic data to every container shipped. Traceability ensures accountability, especially in FDA- or EMA-audited supply chains. We register and update chemical dossiers, providing up-to-date safety data and usage recommendations tailored to regional requirements. When regulations change, such as a shift in the maximum allowable impurity for agrochemicals, we adjust formulation and testing standards accordingly. Regular audits from both clients and regulators push us to maintain these standards, keeping both our customers and our team prepared for future scrutiny.

    Lessons Learned from Real-World Production Issues

    No plant runs without hiccups. A few years back, a minor equipment fault led to batches with slightly elevated water content. Several customers reported cloudy solutions, and we traced it in hours thanks to batch documentation and in-house analytics. We swapped to more robust dewatering units—lessons learned from the ground up. When a pharmaceutical partner flagged trace amide formation, we worked together to adjust process temperatures and keep side reactions down. These realities clarify why direct manufacturer relationships hold value: we have levers to pull to quickly fix issues, unlike resellers or traders who lack direct access to plant equipment.

    Investing in People and Expertise

    Manufacturing specialty chemicals depends as much on skilled people as on technology. Our production crew, many with years of frontline experience, understand the complexities behind every batch. Ongoing training keeps everyone up-to-date with current handling, analysis, and regulatory practices. Visitors often remark on the hands-on knowledge our operators bring—they spot oddities that automation would miss, preventing off-spec batches and catching improvement opportunities. Their feedback drives upgrades, process tweaks, and sometimes even inspires new derivative products.

    Looking Forward: Meeting New Demands

    Markets evolve alongside regulations and technical challenges. New applications for Di-Sec-Butylamine appear as clients stretch its functionality in formulations we hadn’t considered years ago. Fine chemical producers continue looking for more predictable reagents to support rapid synthesis and scaleup. As demand grows for high-purity, more environmentally friendly materials, we invest steadily in purification, solvent recovery, and waste minimization. Our next production line will double throughput but feature more efficient heat exchangers and better raw material handling to further cut emissions per ton produced. Every technical upgrade translates to better, more reliable product for our partners down the supply chain.

    Trust Built from Experience

    In the chemical industry, reputation forms the backbone of sustainable business. Di-Sec-Butylamine earns its place in our product line because it consistently satisfies the challenges set by tough users—whether it’s tighter process specs, tougher regulations, or the drive for better yields. Our experience as direct manufacturers shapes every decision, bridging the gap between plant floor realities and end-use demands. From safe handling to environmental compliance and technical troubleshooting, we see this product not just as a chemical, but as a link in the chain that supports varied, modern industry. That connection runs through every production log, client conversation, and innovation effort, ensuring that each batch delivers on real-world expectations.